- Type 2 diabetes
$49 per month
- Adults and children 10 years or older with Type 2 diabetes mellitus
Drug facts and comparison
You should not use Ozempic if you:
You should talk to your doctor before using Ozempic if you:
You should not use Metformin if you:
You should talk to your doctor before using Metformin if you:
0.25mg once weekly
0.5mg once weekly
1mg once weekly
Once, twice or three times a day
2 mg/1.5 ml pre-filled Ozempic Pen costs $899 on average for 1.5 milliliters
14, 500 mg Metformin oral tablets will cost $11
Ozempic and Metformin are FDA-approved medications that are prescribed for diabetes management. They can be prescribed alone, combined with other medication, or used together for the treatment of type 2 diabetes. Clinical trials show Ozempic and Metformin are effective at reducing blood glucose and HbA1c levels. They both also cause similar gastrointestinal side effects. Let’s take a look at the similarities and differences between these two diabetes drugs.
Ozempic is a brand name diabetes medication manufactured by Novo Nordisk given to adults with Type 2 diabetes to:
Ozempic can help you lower your blood sugar levels when used alongside dietary and lifestyle changes. It causes you to secrete more insulin, helping to lower your blood sugar and reduce your risk of major cardiovascular events, like heart attacks and strokes, if you have cardiovascular disease.
You take Ozempic as a weekly injection. It is injected under your skin (subcutaneous injection), using a pre-filled pen. As it’s a non-insulin medication, your doctor may prescribe Ozempic alongside insulin. Make sure you always use your Ozempic as directed by your doctor.
The active ingredient in Ozempic is called semaglutide. It’s a non-insulin drug that can help lower your blood glucose levels by stimulating the cells in your pancreas that produce insulin (called beta cells).
When you take Ozempic, semaglutide molecules attach to beta cells in your pancreas at sites called glucagon-like peptide-1 (GLP-1) receptors. The semaglutide stimulates these receptors, which makes the beta cells produce more insulin, helping to lower your blood sugar after you’ve eaten.
Semaglutide also encourages the growth of more beta cells in your pancreas, allowing your pancreas to produce higher levels of insulin, reversing any declines in your body’s insulin production.
Other common brands of GLP-1 agonists are Trulicity (dulaglutide), Byetta (exenatide), Bydureon Bcise (exenatide extended-release), and Victoza (liraglutide).
The most common side effects of Ozempic include:
In rare instances, Ozempic can cause more serious side effects, including:
Ozempic can also interact with the following medications:
Talking with your doctor about all medications you take will allow them to pick up any drug interactions and help manage any possible side effects.
Don’t take Ozempic if you:
Talk to your doctor before taking Ozempic if you:
Metformin is a diabetes medication belonging to the drug class called biguanides. Metformin helps to reduce or control the amount of sugar in your blood. It can help with weight loss, while nearly all other diabetes drugs cause weight gain. It is especially useful for diabetic patients struggling with obesity.
Metformin is given to adults and children 10 years or older diagnosed with Type 2 diabetes mellitus to
Metformin is an oral medication taken as a liquid, a tablet, or an extended-release tablet.
The liquid form is usually taken with meals one or two times a day. The regular tablet is usually taken with meals two or three times a day. The extended-release tablet is usually taken once daily with the evening meal.
The tablets are available in four strengths
The recommended starting dose of Metformin hydrochloride tablets is 500 mg orally twice a day or 850 mg once a day, given with meals. Your healthcare provider will advise you on what dosing regime is suitable for you.
Metformin works in three ways:
Metformin is a very useful drug in that it reduces high blood sugar but does not cause hypoglycemia in patients with type 2 diabetes who are not taking insulin injections. It can do this because it does not increase your insulin production like many other diabetes medications.
The most common side effects of Metformin include:
In rare instances, Metformin can cause more serious side effects, including:
Metformin can also interact with the following medications:
Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have to your healthcare provider. Talking with your doctor will allow them to pick up any drug interactions with Metformin and help manage any possible side effects.
Don’t take Metformin if you:
Talk to your doctor before taking Metformin if you:
Read the full prescribing information for Metformin and Ozempic and always speak with your healthcare provider for medical advice about your medicine so they can monitor and evaluate your condition.