Iclusig Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Iclusig cost savings if eligible

If you are eligible to receive your Iclusig prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Iclusig patient assistance?

To be eligible for the Iclusig patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Iclusig enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Iclusig patient assistance program?

Applying for the Iclusig patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Iclusig, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Iclusig assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Iclusig patient assistance program, we will also request your Iclusig medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx an Iclusig coupons provider?

NiceRx does not provide Iclusig coupons, discount cards, or copay cards. We do not offer printable Iclusig manufacturer coupons, Iclusig discounts, rebates, Iclusig savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Iclusig medication with NiceRx.

Can NiceRx help me get Iclusig if I have insurance?

NiceRx may be able to help you access Iclusig patient assistance if:

  • You have a high copay or coinsurance responsibility for Iclusig
  • Your insurance company will not pay for your Iclusig prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Iclusig cost without insurance?

Iclusig prices without insurance will vary by retailer. As a guide, Iclusig oral tablets 10 mg will typically cost around $19,650 for 30 tablets.

How much does Iclusig cost with insurance?

Your individual healthcare plan will determine the copay of Iclusig with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Iclusig?

Iclusig is an FDA (U.S. Food and Drug Administration) approved medication. It is classed as a BCR-ABL tyrosine kinase inhibitor (TKI) indicated for the treatment of adult patients with chronic phase CML, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy, or Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy.

What doses of Iclusig are available?

Iclusig is available in tablet form, in the following doses: 15 mg and 45 mg.

The recommended starting dose is 45 mg taken orally once daily with or without food. Modify or temporarily discontinue dosing for hematologic and non-hematologic toxicity.

Patients should not take two doses at the same time to make up for a missed dose. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Please read the medication guide and the full prescribing information for Iclusig and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Iclusig active ingredients

Iclusig contains the active ingredient ponatinib.

Iclusig side effects

The most common adverse reactions of Iclusig in clinical trials include:

  • Hypertension (high blood pressure)
  • Abdominal pain, constipation
  • Fatigue, headache
  • Dry skin, rash
  • Arthralgia
  • Nausea
  • Pyrexia
  • Vision problems, eye pain
  • Thrombocytopenia (reduced platelets) – unusual bleeding
  • Anemia, neutropenia, lymphopenia (low white blood cells), and leukopenia

In rare instances, Iclusig can cause more serious adverse effects. These can include:

  • Congestive heart failure – chest pain, shortness of breath
  • Pancreatitis – monitor serum lipase monthly
  • Hemorrhage
  • Fluid retention and edema – swelling, rapid weight gain
  • Cardiac arrhythmias
  • Tumor lysis syndrome is caused by a fast breakdown of cancer cells
  • Compromised wound healing and gastrointestinal perforation
  • Arterial occlusive events – a dose reduction to 15 mg should be considered for CP-CML patients
  • Neuropathy

Your doctor will assess the benefits of using Iclusig against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Iclusig to the FDA. Visit, or call 1-800-FDA-1088.

Iclusig drug interactions

Iclusig can interact with other medications. These include:

  • Strong CYP3A inhibitors
  • Avoid eating grapefruit or drinking grapefruit juice

This list is not exhaustive and other prescription drugs may interact with Iclusig.

Iclusig contraindications

You should not use Iclusig if you:

  • Are allergic to the active ingredient ponatinib
  • Are allergic to any of the other ingredients in Iclusig
  • Are pregnant or are planning to become pregnant – Fetal toxicity (use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose)
  • Are less than 18 years of age

Talk to your doctor before using Iclusig if you:

  • Are taking any of the medications that could interact with Iclusig
  • Have heart failure, high blood pressure, heart rhythm problems, long QT syndrome (in you or a family member)
  • Have had a stroke or have a history of blood clots in your blood vessels – Iclusig may cause heart or blood vessel problems that could lead to heart attack, stroke, or death
  • Have diabetes
  • Have high cholesterol
  • Have liver disease
  • Have lactose intolerance
  • Have pancreatitis
  • Are breastfeeding or are planning to breastfeed

Iclusig generic

Iclusig is the trademark brand name for ponatinib. A generic version of ponatinib is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Iclusig savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.