Is Vyvanse generic available?

Key highlights

  • The generic version of Vyvanse is available for sale.
  • The drug patents for Vyvanse expired in 2023.
  • There are several alternatives to Vyvanse for the treatment of ADHD.

Vyvanse is an expensive ADHD medication that is manufactured by Takeda Pharmaceuticals. It was initially approved by the FDA in 2007 and the generic version of Vyvanse is available for sale.

What is Vyvanse?

Vyvanse is an extended-release central nervous system (CNS) stimulant that is classified as a Schedule II controlled substance. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of:

  • Attention deficit hyperactivity disorder (ADHD) in adult and pediatric patients 6 years of age and older
  • Moderate to severe binge eating disorder (BED) in adults

Vyvanse is not an approved weight loss drug. The use of other stimulant medications for weight loss has been associated with heart problems and other serious side effects. The safety and effectiveness of Vyvanse for the treatment of obesity have not been established.

The active ingredient in Vyvanse is lisdexamfetamine. Lisdexamfetamine is a prodrug, which is metabolized into L-lysine and dextroamphetamine once it is in the body. It is thought to work by stimulating the release of certain neurotransmitters such as dopamine and norepinephrine in the brain.

RELATED: What is Vyvanse?

Are there cheaper alternatives to Vyvanse?

There are other prescription medication alternatives to Vyvanse available for the treatment of ADHD. These medications have different strengths, dosages, and indications.

Drug nameApproved usesSide effectsGeneric available
Adderall (amphetamine/dextroamphetine)ADHD and narcolepsyLoss of appetite, headache, insomniaYes
Adderall XR (amphetamine/dextroamphetine)ADHD and narcolepsyLoss of appetite, headache, insomniaYes
Mydayis (amphetamine/dextroamphetine)ADHD and narcolepsyLoss of appetite, headache, insomniaYes
Concerta (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Ritalin (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Quillichew ER (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Qullivant XR (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Focalin XR (dexmethylphenidate)ADHDStomach pain, headache, insomniaYes
Xelstrym (dextroamphetamine)ADHDDecreased appetite, insomnia, headacheNo
Intuniv (guanfacine)ADHDDry mouth, drowsiness, headacheYes
Strattera (atomoxetine)ADHDHeadache, stomach pain, decreased appetiteYes
Kapvay (clonidine)ADHDDry mouth, drowsiness, headacheYes

What is the closest drug to Vyvanse?

Is there a generic Lisdexamfetamine?

Yes, there is currently a generic version of Vyvanse (lisdexamfetamine) available.

How much will Vyvanse generic cost once it’s available?

Generic drugs are typically much less expensive than brand-name medications. The price of generic Vyvanse ranges by pharmacy and is estimated to cost between $50-200 per month, depending on where you buy it.

When will generic Vyvanse become available?

As of 2023, the generic version of Vyvanse is available for sale in the United States.  Patients who are taking this medication can start saving on this medication by purchasing the generic version of the drug.

How do you take Vyvanse (lisdexamfetamine)?

Vyvanse is a capsule or chewable tablet that is typically taken once a day in the morning with or without food. If you cannot swallow the capsule, open it and mix the contents with yogurt, water, or orange juice. You should swallow the entire mixture right away without chewing.

Before taking this medication, you should tell your healthcare provider of all medical conditions you or your child have, including:

  • Heart problems, heart defects, or high blood pressure
  • Personal or family history of psychosis, mania, bipolar disorder, depression, or suicide
  • Circulation problems in fingers and toes (Raynaud’s phenomenon)
  • Are pregnant, plan on becoming pregnant, or are breastfeeding

You should avoid Vyvanse if you have an allergy to other amphetamine products, lisdexamfetamine, or any of the inactive ingredients in its formulation. You should also not take this medication if you are being treated with linezolid or have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days.

Vyvanse side effects

The most common side effects of Vyvanse include:

  • Loss of appetite
  • Trouble sleeping
  • Dry mouth
  • Stomach pain
  • Headache
  • Nausea
  • Irritability
  • Constipation
  • Diarrhea
  • Increased heart rate

Vyvanse can sometimes cause serious adverse reactions such as:

  • Severe hypersensitivity reactions
  • Serious heart problems, including stroke, heart attack, and sudden death
  • Mental health problems such as hallucinations and mania
  • Decreased circulation in your fingers and toes
  • Serotonin syndrome, especially if taken with antidepressants such as SSRIs (fluoxetine and sertraline) or SNRIs (duloxetine and atomoxetine)

Speak with your prescribing doctor about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Vyvanse. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or

RELATED: Vyvanse side effects and how to avoid them

How much does Vyvanse cost?

The estimated cost for a 1-month supply of brand name Vyvanse 30mg capsules without insurance is around $425. The generic version of Vyvanse is significantly cheaper, with savings of up to 80%.

Why is Vyvanse so expensive?

Brand-name drugs are always more expensive than generic drugs.  Vyvanse is so expensive because it is a brand-name medication. Fortunately for patients, there is a generic alternative available for sale that is significantly cheaper.

RELATED: Why is Vyvanse so expensive?

Medically reviewed

A medical professional has reviewed this article.

Jamie Winn, PharmD
Jamie Winn, PharmD

Jamie Winn, PharmD

Medical Writer & Reviewer

Jamie Winn, PharmD

Medical Writer & Reviewer

Dr. Jamie Winn received his Doctor of Pharmacy in 2002 from the University of South Carolina College of Pharmacy, Columbia, SC. Jamie is a medical reviewer for NiceRx.

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Sources (5)

  1. Prescriber's digital reference - lisdexamfetamine dimesylate - Drug Summary

  2. Medscape - lisdexamfetamine (Rx)

  3. Shire - highlights of prescribing information for Vyvanse

  4. - Vyvanse

  5. Healthline - all about Vyvanse

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.