How to get Wegovy online in 2024: The Ultimate Guide

Wegovy injection (semaglutide) is an FDA-approved injectable GLP-1 medication approved for chronic weight management in adults who are overweight or have obesity. As the #1 prescribed medication for chronic weight loss in the United States, there is high demand for this medication due to its proven effectiveness, resulting in a shortage in the supply.

For those seeking an easy and hassle-free method to obtain Wegovy online, getting a prescription or filling it out online at home is possible. This guide outlines the necessary steps to purchase Wegovy conveniently from your home.

Step 1: Speak with an online healthcare provider

Start by scheduling an online consultation with a certified healthcare provider who specializes in weight management and can issue the prescription if medically appropriate, as Wegovy is a prescription medication. The healthcare provider can assess your eligibility for a prescription and discuss whether the medication is suitable for your weight control goals and health needs.

If you don’t have a regular healthcare provider, you can easily book one through a telehealth service such as the NiceRx medical weight loss program. These services offer quick appointment scheduling, often within 48 hours, making it convenient to connect with a licensed clinician who can prescribe Wegovy or compounded semaglutide (same active ingredient as Wegovy) for weight management.

Step 2: Meet with the healthcare provider online

To proceed with getting Wegovy online, the next step involves meeting with a certified healthcare provider via online consultation. During this consultation, you can discuss your weight loss goals and medical history with your provider. They will assess your health status and check whether you meet the criteria for Wegovy treatment.

Your provider may ask for certain details concerning your medical history before prescribing Wegovy to ensure that you are in good health and do not have any underlying conditions that could pose risks while taking Wegovy.

It’s essential to discuss the potential risks and side effects of Wegovy with your provider during the consultation. The most common side effects with an incidence of 5% or higher include abdominal pain, headache, nausea, vomiting, dyspepsia, etc. Anti-nausea medication is often prescribed alongside this medication. There are some serious adverse effects associated with Wegovy, such as pancreatitis, serious allergic reactions, increased heart rate, etc. Your doctor will help assess whether the benefits of Wegovy outweigh its potential risks for your health profile. You should seek immediate medical advice from your provider if you experience any adverse side effects.

Step 3: Get a Wegovy prescription for weight loss

The third step involves receiving a prescription from your provider. The provider will issue a prescription only if you are eligible to receive this medication based on your health history to ensure that it is safe to take the medication as prescribed. This medication should be used alongside a reduced calorie diet and increased physical activity.

Wegovy is available in 5 different strengths. Your provider will prescribe a low dose of Wegovy initially with 0.25 mg then escalate to the maintenance dose of 0.5 mg, 1 mg, 1.7 mg, or up to 2.4 mg. They will prescribe injections delivered through pre-filled syringes or single-dose pens to administer the doses based on your convenience.

Along with the prescription, your provider will explain how to administer the medication, what to do when you skip a dose, and possible side effects associated with the medication. Follow-up visits may be necessary to obtain new prescriptions as your dosage increases. These appointments allow your provider to optimize your treatment plan, ensuring you receive the maximum benefit from Wegovy while addressing any concerns or adjustments needed along the way.

Step 4: Get prior authorization from your insurance if needed

The fourth step in obtaining Wegovy is ensuring you have prior authorization from your insurance provider. Be sure to check with your insurance provider to see if you need prior authorization for Wegovy to be covered under insurance. Your healthcare provider’s office can assist you in obtaining this authorization by submitting the necessary documentation, including medical necessity and supporting clinical information for insurance coverage.

By obtaining prior authorization, you can smoothly integrate Wegovy into your weight loss journey while ensuring financial coverage for your treatment.

Step 5: Navigate challenges with Wegovy shortages

Novo Nordisk is putting lots of effort into increasing Wegovy production, now seeing 25,000 new U.S. patients start weekly. Despite this, demand still exceeds supply.

To manage your Wegovy prescription, contact your pharmacy well in advance for refills and be specific about your dose. If shortages persist, consult your healthcare provider about where to find Wegovy in stock or for alternative solutions.

Novo Nordisk has committed to resolving issues, operating manufacturing lines around the clock, and making significant investments in new facilities.

You can check the FDA report for Wegovy dose availability and shortage reasons.

Step 6: Buy Wegovy online or at a local pharmacy

The final step to getting Wegovy online is ensuring your prescription is filled by a reputable online pharmacy.

According to U.S. law, you can buy Wegovy online under the Federal Food, Drug, and Cosmetic Act only with a valid prescription. This prescription must be for a genuine medical need and must be issued by a medical professional that is licensed in your state.

Once you have had an online consultation with a certified medical professional and checked the coverage status, you can proceed to purchase the medication online.

There are many national pharmacies and local pharmacies that offer home delivery services. Check if the pharmacy provides this option for your added convenience. Additionally, it’s important to verify that the pharmacy has adequate stock of Wegovy before placing your order.

If Wegovy shortages persist, compounded semaglutide might be an alternative available from compounding pharmacies. However, FDA advises against using a compounded drug if it contains salt. If considering compounded semaglutide, consult your healthcare professional to discuss potential risks and benefits.

Some individuals might consider Ozempic as an alternative to Wegovy since both medications contain the active ingredient semaglutide. However, manufacturers advise against this interchangeability due to FDA approvals for distinct indications. Ozempic is approved for managing type 2 diabetes, while Wegovy is specifically approved for chronic weight control. Nonetheless, Ozempic is commonly prescribed off-label.

Speak with an online provider through NiceRx

You can contact an online provider at NiceRx. At NiceRx, our team of experts are dedicated to providing guidance and support for purchasing medications online, including compounded Semaglutide which contains the same active ingredient as Wegovy. Our telehealth services allow you to consult with healthcare professionals who can assist you throughout the process.

FAQs about getting Wegovy online

Is it legal to buy Wegovy online?

Yes, it is legal to buy Wegovy online, provided that the purchase is made with a valid prescription from a certified provider, issued for a legitimate medical purpose. According to US law, this prescription must be based on a medical evaluation of the patient by the prescribing practitioner or a covering practitioner.

Do you need a prescription for Wegovy?

Yes, you need a valid prescription to buy Wegovy, whether from a local pharmacy or online. Wegovy is a prescription-only drug, and the prescription must be issued by a valid medical professional in your state.

How do I get an online prescription for Wegovy for weight loss?

To obtain an online prescription for Wegovy for weight loss, start by scheduling an appointment with a certified physician who offers telehealth services. During your online consultation, discuss your weight loss goals and provide your medical history including any other prescription and over-the-counter medicines, vitamins, and herbal supplements you are currently taking to the physician. They will assess your eligibility criteria for Wegovy based on medical guidelines and evaluate whether it is suitable for your health condition. If the physician determines that Wegovy is appropriate for you, they will issue a prescription.

What are the requirements to qualify for a Wegovy prescription?

To qualify for a Wegovy prescription, adults must have obesity or be overweight with a body mass index (BMI) of 30 kg/m² or greater, or 27 kg/m² or greater with at least one associated weight related health condition such as high blood pressure, type 2 diabetes mellitus, or abnormal cholesterol levels. Additionally, adolescents aged 12 and above must have an initial BMI at the 95th percentile or greater for their age and sex. Both adults and adolescents should also be following a reduced-calorie diet and engaging in increased physical activity as part of their weight control efforts. These criteria ensure that Wegovy is prescribed appropriately to support effective weight loss and improve overall health outcomes.

What about Wegovy for people with heart disease?

On March 2024, Wegovy was approved for helping to reduce the risk of heart attack, stroke, and cardiovascular death in people with heart disease and overweight or obesity. This medication will help with your overall cardiovascular health.

How much does Wegovy cost?

The cost of wegovy can vary depending on factors such as insurance coverage, pharmacy pricing, and eligibility for savings programs. Without insurance, the list price for a one-month supply of Wegovy is approximately $1,349.02. However, many patients may pay significantly less through insurance plans or savings offers. You can check about insurance companies that provide insurance coverage and savings offers online.

Who should not use Wegovy?

Wegovy should not be used by individuals with certain medical conditions or risk factors. Specifically, do not use this weight loss drug if:

  • You or your family had a health condition related to the thyroid or endocrine system like medullary thyroid carcinoma and Multiple Endocrine Neoplasia syndrome type 2.
  • You have had a serious allergic reaction like swelling of your face, lips, tongue, or throat; fainting or feeling dizzy; problems breathing or swallowing to semaglutide or any of the ingredients in Wegovy.
  • You are pregnant or planning to become pregnant, as Wegovy may cause fetal harm. When pregnancy is recognized, discontinue the medication immediately.
  • For females and males of reproductive potential, discontinue Wegovy at least 2 months before a planned pregnancy due to the long half-life of semaglutide.

Will I lose weight with Wegovy?

Yes, you will start losing weight after taking Wegovy as it is an approved and potent weight loss medication. It has been shown to help individuals lose a significant amount of weight when used in conjunction with a reduced-calorie diet and increased physical activity. You can check your potential weight loss with Wegovy. Studies have demonstrated that semaglutide, the active ingredient in Wegovy, leads to significant weight loss, ranging from 9.6% to 17.4% of initial body weight. However, a new medication, tirzepatide, marketed under the brand name Mounjaro, has shown even greater efficacy, with clinical trials reporting weight loss of up to 20.9% of initial body weight.

What happens after I stop taking Wegovy?

After you stop taking Wegovy, you may regain weight. A study found that one year after stopping Wegovy and lifestyle changes, people regained about two-thirds of the weight they had lost, and their cardiometabolic health, such as blood pressure and cholesterol levels, also worsened.

Where can I find Wegovy in stock?

Are you struggling to find Wegovy in stock? You are not alone. This weight loss drug’s popularity has exceeded supply and has led to a shortage of Wegovy.

Although finding Wegovy will require a bit of work, it is still in stock at some pharmacies.

For a more comprehensive insight into Wegovy, its current availability, and alternative options, continue reading below.

What is Wegovy?

Wegovy (semaglutide) is a prescription medication indicated for people with obesity or overweight as an addition to lifestyle modifications in chronic weight management. It received approval from the Food and Drug Administration (FDA) in 2021. Administered as a once-weekly injection, it is available in five doses: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. Clinical studies revealed that participants lost an average of 14.9% of their weight over 68 weeks on semaglutide, compared to those on a placebo.

Semaglutide, the active ingredient in Wegovy, belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. These medications are recognized for their ability to aid in weight loss and improve blood sugar control. GLP-1 is a hormone that is naturally produced in the body and helps regulate appetite by signaling fullness after eating. By mimicking this hormone, GLP-1 receptor agonists like semaglutide trick the brain into feeling full even in the absence of food, thereby reducing food intake.

Wegovy is prescribed for adults who are classified as obese, with a body mass index (BMI) of 30 or higher, or overweight, with a BMI of 27 or higher, and have at least one weight-related condition such as high blood pressure, high cholesterol, or type 2 diabetes. It is also approved for use in adolescents aged 12 and older who have a BMI at the 95th percentile or higher for their age and sex.

However, Wegovy is not suitable for everyone. It should not be prescribed to patients with a family history of thyroid cancer or those who have had serious allergic reactions to semaglutide or any of its components.

Patients starting Wegovy are initially prescribed the lowest dose of 0.25 mg to minimize the occurrence of gastrointestinal side effects such as nausea, vomiting, or diarrhea. The dosage is gradually increased to the highest dose of 2.4 mg over a period of time, based on the patient’s tolerance and response to the medication.

While Wegovy can be highly effective in aiding weight loss, it is also important to be aware of serious side effects, which include but are not limited to the possibility of thyroid cancer, pancreatitis (inflammation of the pancreas), gallbladder problems (e.g., abdominal pain, clay-colored stools), allergic reactions, or kidney problems.

Wegovy represents a significant advancement in the management of chronic weight issues, offering a promising option for those struggling with obesity and weight-related conditions. However, like any medication, it must be used under the supervision of a healthcare professional to ensure safety and effectiveness. Regular monitoring and open communication with your healthcare provider are crucial to achieving the best possible outcomes while minimizing risks.

Why is Wegovy out of stock?

Due to remarkable results with reduction in body weight, Wegovy has gained popularity in patients that are seeking support with weight loss. It has been endorsed by celebrities such as Elon Musk and Oprah which has contributed to widespread awareness of its benefits.

Novo Nordisk, the only FDA-approved company to manufacture it, continues to commit to its production and distribution. But there is still an increasing amount of interest for it, therefore, overwhelming their ability to produce enough supplies. Therefore, patients are having a hard time finding the medication.

Novo Nordisk are limiting the supply of the three lower doses (0.25 mg, 0.5 mg, 1 mg) to US wholesalers for distribution to pharmacies to support patients. On the other hand, they do not foresee any interruptions with the higher maintenance doses (1.7 mg and 2.4mg).

At the time of publishing this article, Novo Nordisk reported that it was shipping all dosage strengths. However, the FDA has reported ongoing shortages of all dosage strengths with the exception of the 2.4 milligram dosage strength.

Prior to you and your healthcare provider planning to start weight loss treatment on Wegovy, make sure to check with local pharmacies or reputable online pharmacies to make sure you can purchase the medication at your prescribed dosage strengths.

Where can you get Wegovy?

Since Wegovy is a prescription-only medication, you need to be thoroughly assessed by a healthcare professional to determine if the medication is appropriate for you.

Schedule an appointment with your doctor and discuss the recommended approach. During this consultation, they will evaluate your medical history, current health status, and weight loss goals. The benefits, potential side effects, and how it fits into your overall plan should be explained to you too. Your conversation with them should cover any concerns you have and should have set realistic expectations.

It is also crucial to have a shared decision-making process with your healthcare provider before starting the medication, especially given the current supply shortage. This collaborative approach ensures that both you and your doctor are aligned on the best course of action.

After obtaining a prescription, your main options are to buy the medication from one of the large nationwide pharmacy chains, your local pharmacy or online pharmacies. Most pharmacy chains including Walgreens, Rite Aid, Walmart, Costco and CVS have Wegovy in stock, as well as many local pharmacies.

Where can I find Wegovy in stock?

As previously mentioned, the FDA has included Wegovy in the list of medications that are currently in shortage, making it challenging to find a pharmacy that has it in stock.

You will still be able to navigate the process of obtaining the medication more effectively by being proactive in exploring your options to enhance your chances of successfully starting and maintaining your treatment.

Here are some options you can try:

Ask your healthcare provider

You can try asking your healthcare provider if they know of any local or online pharmacies that have it. They might have experience with other patients trying to locate it and can help connect you to pharmacies with available stock.

Online pharmacies

Online pharmacies might have supplies and could even offer the convenience of home delivery. Some large companies that might have it include walgreens.com, cvs.com, and riteaid.com.

Be meticulous when choosing an online pharmacy: ensure they require a prescription, can provide a physical address and telephone number in the U.S., and have a licensed pharmacist available for queries. You can also check if their pharmacy license is listed in the database on the FDA’s BeSafeRx website.

Local pharmacies

Call your local pharmacies to inquire about availability. While smaller, independent pharmacies might be worth a try, you might have better luck with larger chains such as Walgreens, CVS, Walmart, or RiteAid.

Contacting them well before you need the medication can increase your chances of securing it. Some pharmacies may even offer delivery services, saving you the trip if the pharmacy is far from home.

Medical clinics

Some medical clinics have pharmacies that can fill prescriptions for their patients. You might be able to get it from these locations. If your healthcare provider or their clinic has a partner pharmacy, they might notify you when the medication becomes available.

Wegovy alternatives

Several alternatives can also lead to weight loss. It is essential to seek medical advice and discuss these options with your healthcare provider to determine which aligns best with your situation and goals. As with any medication, these alternatives have potential risks and side effects that should be explained to you before starting.

It is important to note that if you are already on Wegovy, you should not take these alternatives at the same time. Combined use of these medications can lead to unintended side effects and interactions that could be harmful.

Compounded Semaglutide (same active ingredient as Wegovy)

With the ongoing shortage of Wegovy, some compounding pharmacies may be able to prepare compounded semaglutide, provided it meets specific requirements in the Federal Food, Drug, and Cosmetic (FD&C) Act. However, patients and healthcare professionals should be aware that some compounding pharmacies may use salt forms of semaglutide (semaglutide sodium and semaglutide acetate), which differ from the active ingredient in Wegovy. Compounded versions are not approved by the FDA.

Zepbound (tirzepatide)

Zepbound was approved by the FDA for weight loss in November 2023 and belongs to the same drug class as Wegovy. It is a once-weekly injection with doses increased over 4-20 weeks. Studies have shown that patients reduced 5-18% of their weight over 72 weeks compared to those receiving a placebo. Zepbound can cause gastrointestinal side effects such as nausea, diarrhea, vomiting, constipation, and abdominal pain.

Saxenda (liraglutide)

Saxenda is another FDA-approved injection for weight management. Like Wegovy and Zepbound, Saxenda demonstrates significant weight reduction of about 5-10% in clinical trials. It is a daily injection that starts at 0.6 mg and is gradually increased over four weeks.

Contrave (bupropion-naltrexone)

Contrave is an oral medication containing two active ingredients that work synergistically to aid weight loss. Studies reveal a 5-10% reduction in patients over 56 weeks. If a reduction of at least 5% is not achieved after 12 weeks, Contrave should be discontinued.

Xenical and Alli (orlistat)

Orlistat is an oral medication available under two brand names, Xenical and Alli. Xenical (120 mg) requires a prescription, while Alli (60 mg) can be obtained over-the-counter. Orlistat works by preventing the absorption of fatty acids from food by inhibiting gastrointestinal and pancreatic lipases, resulting in a 2.4% reduction over four years.

Qsymia (phentermine-topiramate)

Phentermine is known to affect food intake, while topiramate, originally approved for seizure management and migraine prophylaxis, was observed to cause weight loss in patients. Qysmia, the combination of these two medications, is an oral medication designed as an adjunct to lifestyle modifications when managing obesity. It requires a more conservative prescribing approach as it is contraindicated for some groups such as pregnant women due to the teratogenic nature of topiramate.

Type 2 diabetes medications that are being prescribed off-label for weight loss

There are medications approved for type 2 diabetes that have shown to cause weight loss, leading to their off-label use. Prescribers started writing prescriptions for these medications to help patients lose weight instead of their intended use.

Mounjaro (tirzepatide)

Mounjaro contains the same active ingredient as Zepbound; however, it is only approved for type 2 diabetes mellitus in conjunction with exercise and healthy diet. Its use for weight loss is off-label, which is not recommended.

Ozempic (semaglutide)

Ozempic has the same active ingredient as Wegovy. It is also a once-weekly injection but they have different formulations, prescribing information, and dosing recommendations. Ozempic is approved for type 2 diabetes with its off-label use for weight loss. It is advised by Novo Nordisk that it is not interchangeable with Wegovy.

Trulicity (dulaglutide)

Trulicity is another injection indicated for type 2 diabetes. It works to decrease high blood sugar levels and even provide cardiovascular benefits to patients. Patients on this medication experience weight loss, but it is not approved for managing obesity.

When will Wegovy be back in stock?

The availability of Wegovy has been a persistent issue, even though there have been efforts to significantly increase production capacity. Despite these efforts, supply remains limited, and there is no specific date when Wegovy will be widely available again.

Novo Nordisk, the manufacturer of Wegovy, has acknowledged the supply constraints and indicated that patients may continue to face difficulties in obtaining the medication, particularly the lower doses (0.25 mg, 0.5 mg, 1 mg) through September 2024. While they are committed to ensuring that maintenance doses (1.7 mg and 2.4 mg) remain available to support patients already on Wegovy, the situation for new patients or those in the early stages of their treatment is more challenging.

The ongoing supply issues highlight the high demand for Wegovy and the challenges in meeting this demand swiftly. While the manufacturer is taking steps to improve production and distribution, the exact timeline for widespread availability remains uncertain. Patients and healthcare providers must work closely together to navigate this period, exploring alternative options and staying vigilant about new information regarding Wegovy’s availability.

In conclusion, while there is no definite answer as to when Wegovy will be back in full stock, staying proactive and informed can help manage the situation more effectively. Regular communication with healthcare providers and consistent monitoring of pharmacy stocks are key strategies in navigating this shortage. As production efforts ramp up, it is hoped that the supply will eventually meet the demand, allowing more patients to benefit from this effective weight loss treatment.

Get a Semaglutide prescription online through NiceRx

Losing weight is a journey best undertaken with medical supervision to ensure safety and effectiveness. With all the different available weight loss options for you, it is crucial to seek professional medical advice before starting any new treatment. One of the promising treatments is semaglutide which has shown significant success in aiding weight reduction. If you want to know more about this and your suitability for it, try NiceRx online platform to get a prescription.

This article is not intended to be taken as medical advice. Speak with your healthcare provider when considering options that are suitable for you as they are still the best resource for making a safe and informed decision about your treatment.

Xifaxan side effects and how to avoid them

Xifaxan® is an FDA (U.S. Food and Drug Administration) approved antibacterial medication manufactured by Salix Pharmaceuticals. It is used for the treatment or prevention of infections that are caused by bacteria only. Primarily for treating travellers’ diarrhea (TD) caused by Escherichia coli in patients of 12 years of age or older, irritable bowel syndrome with diarrhea (IBS-D) in adults, and reducing the recurrence risk of overt hepatic encephalopathy (HE) in adults.

While Xifaxan is generally safe and well-tolerated, there are some potential side effects that people should be aware of. The most common side effects of Xifaxan include headaches, swelling of the legs or abdomen due to fluid accumulation, nausea, extreme tiredness, and dizziness. Not everyone treated with Xifaxan will experience all of these side effects. It depends on the condition being treated. Less common, but serious side effects include rash, hives, itchiness, difficulty breathing or swallowing, hoarseness, watery or blood-stained diarrhea along with fever and stomach cramps, and swelling of the face, lips, tongue, throat, eyes, hands, or legs.

Learn more about the side effects of Xifaxan and what you can do to avoid them.

What is Xifaxan (rifaximin)?

Xifaxan is an antibacterial drug that contains rifaximin as an active ingredient. Rifaximin is a gut-selective, nonsystemic and oral antimicrobial agent. It acts only in the gastrointestinal tract and therefore causes minimal side effects compared to systemic antibiotics. It works by binding to the beta-subunit of bacterial DNA-dependent RNA polymerase. It prevents bacteria from synthesizing proteins and, in turn, inhibits bacterial growth.

Xifaxan dosage

It is available in tablet form in 200 mg and 550 mg strengths. It should be taken at the same time every day with or without food. Take Xifaxan exactly as directed by your doctor or pharmacist. Your doctor will recommend the optimal dose depending on the medical condition to be treated.

For the treatment of TD, 200 mg tablets are prescribed thrice a day for 3 days.

For the treatment of HE, 550 mg tablets are prescribed twice a day.

For the treatment of IBS, 550 mg tablets are prescribed thrice a day for 14 days.

What are the side effects of Xifaxan?

Most common side effects of Xifaxan:

  • Headaches
  • Swelling of legs or abdomen due to fluid retention
  • Nausea
  • Extreme tiredness
  • Dizziness.

Rare and serious side effects of Xifaxan: 

  • Hives
  • Rash
  • Itchiness
  • Difficulty breathing or swallowing
  • Hoarseness
  • Swelling of the face, lips, tongue, throat, eyes, hands, or legs
  • Watery or blood-stained diarrhea along with fever and stomach cramps

If you experience any of these serious side effects, stop taking Xifaxan and seek medical attention immediately.

You are encouraged to report the adverse effects of prescription drugs to the FDA by visiting www.fda.gov/medwatch or calling 1-800-332-1088.

Side effects of SIBO treatment with Xifaxan

SIBO (Small Intestinal Bacterial Overgrowth) is an abnormal condition characterized by excessive growth of bacteria in the small intestines. Xifaxan is not FDA-approved for SIBO treatment but is indicated for off-label use. Research has shown that Xifaxan can help manage SIBO. As Xifaxan acts only in the gastrointestinal tract, it causes fewer side effects including nausea, constipation, fatigue, gas formation, and headache.

It rarely affects liver functions, worsens diarrhea in some people, and can lead to gut infections by promoting the growth of Clostridium difficile.

How long do Xifaxan side effects last?

Xifaxan side effects are temporary and subside quickly within a day or two. Rarely, it causes overgrowth of C. difficile and puts you at risk for CDAD. While some side effects may require additional treatment. Speak to your doctor about what side effects you face, how long they last, and how to manage them at home.

What are the side effects of Xifaxan after stopping?

Xifaxan is considered a safe medication. There won’t be any side effects after stopping the use.

Xifaxan long-term side effects

According to the information available to date, Xifaxan has no long-term side effects unless you have lung disease.

Anxiety side effects

Anxiety can fill your brain with racing and unwanted thoughts, unnecessary worries, fears, irregular heartbeat, sleeplessness, and many more. Try to relax by practicing nurturing habits like drawing, painting, socializing, walking barefoot on the grass, or taking a warm water bath.

Fatigue side effects

Fatigue can make you suffer from moodiness, tiredness, lack of interest, sleepiness, and many more. To overcome this, exercise regularly and do activities that make you feel happy and energized.

Xifaxan side effects with alcohol

Consuming alcohol while on Xifaxan treatment is neither hazardous nor safe. According to a study conducted by the American College of Gastroenterology, alcohol consumption can impact gut health and causes bloating, abdominal pain, gas, diarrhea, or constipation. So, it’s better to avoid alcohol during this treatment.

Foods to avoid while taking Xifaxan

There is no strong evidence on the foods to avoid while on Xifaxan, but patients with IBS are advised to avoid:

  • Dairy products
  • Insoluble fiber foods (certain fruits and vegetables, and whole grains)
  • Deep-fried foods
  • Caffeinated drinks
  • Processed foods
  • Gluten or wheat
  • Garlic, onions, broccoli, and cauliflower
  • Alcohol
  • Chocolates or sugar-free sweeteners

Patients with TD are advised to avoid:

  • Raw leafy vegetables (spinach, lettuce, and cabbage)
  • Unpeeled or unwashed vegetables or fruits
  • Undercooked meats

You can replace the above foods with eggs or well-cooked meat, fish, almond milk, grains (oats, rice, corn, quinoa), cheeses (cheddar, feta, brie), vegetables (tomatoes, potatoes, cucumbers, zucchini), tofu, pumpkin seeds, sesame seeds, sunflower seeds, and fruits (bananas, blueberries, kiwi, strawberries).

You can consult a registered dietitian or nutritionist if you want to get a personalized diet menu based on your condition.

Xifaxan drug interactions

Xifaxan can interact with other medications including:

  • P-glycoprotein inhibitors+ Xifaxan

This combination increases the systemic exposure of rifaximin.

  • Warfarin + Xifaxan

This combination alters blood clotting times. So, warfarin dose adjustment is required.

  • CYP3A4 Substrates + Xifaxan

A study discovered that Rifaximin induces CYP3A4, an important enzyme found in the liver and intestines. This combination may deactivate the drug. However, in patients with normal liver function, optimal doses of Xifaxan do not induce CYP3A4. But its effect in patients with compromised liver function is still unknown.

This list is not exhaustive and other prescription drugs may also interact with Xifaxan. Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins or nutritional supplements, and herbal products.

Xifaxan warnings & precautions:

You should not use Xifaxan if you:

  • Are allergic to the active ingredient rifaximin
  • Are allergic to any of the Xifaxan ingredients
  • Have travelers’ diarrhea that is not caused by E. coli or strongly suspected bacterial infection. If prescribed in this condition, it may not benefit the patient and increases the risk of developing drug-resistant bacteria.
  • Have Clostridium difficile-associated diarrhea (CDAD). CDAD has been reported following the use of antibacterial agents. These agents alter the normal flora of the colon, leading to the overgrowth of C. difficile and increasing mortality. These infections are unresponsive to antimicrobial therapy. So a history of CDAD should therefore be carefully evaluated in patients with diarrhea even after antibiotic use.

Use with caution:

  • In patients with severe hepatic impairment
  • During concomitant administration with P-glycoprotein inhibitors

Talk to your doctor before using Xifaxan if you: 

  • Have a fever or blood-stained stools
  • Have or ever had liver disease
  • Are a pregnant or planning to conceive or breastfeeding
  • Are taking or have ever taken prescription or OTC medications, vitamin or nutritional supplements, or herbal products

You should always check with your doctor or pharmacist before taking any medication, including Xifaxan, to make sure it is safe for you.

How to avoid Xifaxan side effects?

The best way to avoid side effects is to take Xifaxan as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or lesser doses than prescribed.

If you experience any unusual side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the Xifaxan side effects.

Inform your doctor if your diarrhea persists or worsens 24 to 48 hours after taking Xifaxan. Your doctor will discontinue Xifaxan and choose other antibiotics. Adapt the below activities to avoid Xifaxan side effects:

1. Stick to the recommended dose

Take Xifaxan exactly as recommended by your doctor. Do not take more or lesser doses than prescribed.

2. Monitor yourself

Like all medicines, Xifaxan also has some side effects. So, keep an eye on the signs and symptoms of any side effects you may face during Xifaxan treatment. Consult your doctor right away if any unusual symptoms occur and get the necessary medical attention.

3. Follow a healthy lifestyle

Xifaxan can cause a variety of side effects. So, have a healthy diet and lifestyle to better manage the side effects at home. A healthy lifestyle can also help you recover faster.

4. Avoid alcohol consumption

Alcohol can cause gut problems like constipation or diarrhea, gas, bloating, and abdominal pain. So try to avoid alcohol or limit consumption.

5. Get your liver tested regularly

Xifaxan may interfere with normal liver functioning. So go for liver examination at specific intervals of time to ensure you are on safe treatment with Xifaxan.

6. Know the signs and symptoms of Xifaxan side effects

The most common signs and symptoms of Xifaxan side effects include but are not limited to headaches, peripheral edema, nausea, fatigue, ascites, and dizziness. If you experience any of these symptoms, consult your doctor for medical advice.

7. Tell your doctor about all medications you are taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter medicines, vitamins, and herbal supplements, as they can interact with Xifaxan.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your treatment progression. Your doctor will monitor your condition and may adjust the dose of Xifaxan as needed.

How does Wegovy work for weight loss?

Approximately 70% of adults in the United States are considered overweight or obese. Obesity is a serious health issue associated with complications such as cardiovascular disease, stroke, diabetes, and death. It is also linked to an increased risk of certain types of cancer. Diet and exercise are the first steps in losing weight and getting healthy. If diet and exercise aren’t enough, your doctor may prescribe a medication such as Wegovy (semaglutide) to help with weight management. Keep reading to find out more about Wegovy and how it works to help you lose weight.

What is Wegovy (semaglutide)?

Wegovy is a glucagon-like peptide-1 or GLP-1 receptor agonist that is manufactured by Novo Nordisk. It is approved by the U.S. Food and Drug Administration (FDA) along with a reduced calorie diet and increased physical activity for chronic weight management in adults with a body mass index (BMI) of:

  • 30 kg/m^2 or greater (obesity)
  • 27 kg/m^2 or greater (overweight) with at least 1 weight-related condition such as high blood pressure, type 2 diabetes (T2DM), or high cholesterol

It is also used in pediatric patients 12 years of age and older with a BMI at the 95th percentile or greater for their age and sex, which is considered obese.

The active ingredient in Wegovy is semaglutide. Semaglutide is available in other versions used to manage blood glucose levels in patients with T2DM. It is marketed as a subcutaneous injection under the brand name Ozempic and as an oral tablet under the brand name Rybelsus. Ozempic and Rybelsus are not FDA-approved as weight loss drugs.

How does Wegovy work for weight loss?

Wegovy is a brand-name weight loss medication that belongs to the class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists. It stimulates your pancreas to release insulin while preventing the release of glucagon. These 2 hormones work together to regulate your blood sugar levels. Insulin is released in response to food and helps your body absorb sugar to use for energy. Glucagon is released when your blood sugar is low signaling to your liver to break down and secrete stored sugars into your bloodstream.

So how does it work for weight loss? In addition to increasing the production of insulin, GLP-1 also targets areas of your brain that help regulate appetite after eating. Wegovy injections also slow down have fast the food you eat leaves your stomach, which makes you feel full (satiety) for longer. By helping you feel full and satisfied after a meal, it can lead to reduced cravings and food intake. Wegovy works best when it is used along with lifestyle changes including a healthy diet and regular exercise.

How effective is Wegovy for weight loss?

The safety and efficacy of Wegovy have been demonstrated in several clinical trials. It found that when used along with diet and exercise:

  • 83% of adult patients using Wegovy lost 5% or more body weight, compared to 31% taking a placebo
  • 66% of adult patients using Wegovy lost 10% or more body weight, compared to 12% taking a placebo
  • 48% of adult patients using Wegovy lost 15% or more body weight, compared to 5% taking a placebo

How much weight can you lose with Wegovy?

In a clinical study of almost 2,000 adults with obesity or excess weight that lasted 68 weeks, those taking Wegovy lost more weight when compared to placebo. The average starting weight in each group was around 232 pounds. Adults taking Wegovy lost an average of 35 pounds or around 15% of their body weight. Those taking placebo lost an average of 6 pounds or around 2.5% of their body weight.

How fast do you lose weight with Wegovy? 

You may start to see a decrease in your appetite and some weight loss within the first 4 weeks of Wegovy treatment but its full effects can take several months or longer. In one clinical study, some people were switched to placebo after 20 weeks while others stayed on Wegovy. Between weeks 20 to 68, Wegovy patients continued to lose weight while those on placebo saw weight gain.

What are some side effects of Wegovy?

The most common side effects of Wegovy seen in clinical trials when compared to placebo include:

  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Abdominal pain
  • Headache
  • Fatigue
  • Bloating
  • Heartburn
  • Acid reflux
  • Gas
  • Burping
  • Common cold symptoms
  • Increased heart rate

Wegovy can sometimes cause serious side effects such as:

  • Serious, life-threatening allergic reactions (hives, swelling of the tongue or throat, and trouble breathing)
  • Pancreatitis (inflammation of your pancreas)
  • Acute gallbladder disease including gallstones
  • Increased risk of thyroid cancer or thyroid tumors
  • Hypoglycemia (low blood sugar levels), especially if used along with other diabetes drugs such as an insulin secretagogue or insulin
  • Diabetic retinopathy complications
  • Acute kidney injury and worsening of chronic renal failure
  • Increased risk of suicidal thoughts and behaviors

Speak with your healthcare provider about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Wegovy. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

How do you take Wegovy?

  • Read the Prescribing Information, Instructions for Use, and Medication Guide that comes with Wegovy.
  • Use this medication exactly as your doctor prescribes it to you. Do not change your dose or stop taking Wegovy without discussing it with them first.
  • Your doctor should demonstrate how to use Wegovy before you give your first dose.
  • Wegovy is injected under the skin of your abdomen, thigh, or upper arm. You should not inject this medication into a muscle or vein. Rotate your injection site with each Wegovy injection.
  • Wegovy is injected once a week on the same day each week. You can inject this medication at any time of the day. You can change the day of the week you use Wegovy as long as the last dose was given at least 2 days before.

What should you tell your doctor before starting Wegovy?

Before beginning Wegovy treatment, tell your doctor about all your medical conditions, including:

  • Kidney or pancreas problems
  • Type 2 diabetes and a history of diabetic retinopathy
  • Current or history of depression, suicidal thoughts, or mental health issues
  • Personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Are pregnant, plan to become pregnant, or are breastfeeding 

Does Wegovy cause hair loss?

According to the manufacturer, hair loss was seen in 3% of obese or overweight adults taking Wegovy for chronic weight management. It was seen in 1% of adults taking placebo in the same study.

What foods can you eat while on Wegovy?

To get the best results from a weight loss program, medications such as Wegovy should be taken along with a healthy diet and regular exercise. This means avoiding foods processed foods that are high in sugar, cholesterol, trans fats, and saturated fats. Instead, you should make healthy food choices that can include:

  • Lean meats that are high in protein such as turkey, chicken, tuna, lentils, and chickpeas
  • Fresh fruits and vegetables
  • Whole grains such as whole-wheat pasta, quinoa, and brown rice

How often can you take Wegovy?

Wegovy is given as a subcutaneous injection (under the skin) in your stomach, thigh, or upper arm once a week. It should be given on the same day of the week each week.

Buy compounded semaglutide near me and save money

While it may not be possible to buy compounded semaglutide from your local pharmacy, licensed compounding pharmacies can supply compounded semaglutide by mail order with a prescription from a licensed U.S. healthcare provider.

Semaglutide is the active ingredient in Ozempic and Wegovy, two popular GLP-1 medications manufactured by Novo Nordisk. Learn more about compounded semaglutide and how to safely buy this medication online and receive it at your doorstep, if approved for a prescription.

What is compounded semaglutide?

Compounded semaglutide are customized versions of the medication made by a compounding pharmacy personally for each patient. It contains the same active ingredient as the brand name GLP-1 drugs, Ozempic and Wegovy. When a medication is in shortage, compound pharmacies may be able to prepare a compounded version of the medication if they meet certain requirements in the Federal Food, Drug, and Cosmetic (FD&C) Act. As of April 2024, several strengths of Wegovy are listed on FDA’s Drug Shortages list.

Ozempic is an FDA-approved medication for the treatment of type 2 diabetes in adults, and Wegovy is an FDA-approved chronic weight management medication that was recently approved for reducing the risk of heart attacks, strokes and cardiovascular-related death in adults who have heart disease and are overweight or have obesity. Other similar GLP-1 medications include Zepbound and Mounjaro, which contain the active ingredient tirzepatide.

Compounding is a practice in which licensed compounding pharmacies combine, mix, or alter a drug’s ingredients to create a medication customized for an individual patient’s needs.

Semaglutide belongs to a class of prescription drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists, which mimics the GLP-1 hormone that releases the gastrointestinal tract when eating and causes the body to produce more insulin, which reduces blood sugar levels. GLP-1 drugs also interact with the parts of the brain that help to reduce appetite and cause the feeling of fullness. Semaglutide is effective for the promotion of weight loss and lowering blood sugar levels in patients who are overweight or have obesity.

Is it safe to get semaglutide from a compounding pharmacy?

The FDA (U.S. Food and Drug Administration) warns that some products sold as “compounded semaglutide” may not contain the same active ingredient as the FDA-approved brand name products, and may contain the salt formulation of the drug, which is considered unsafe.

Products containing the salt form, such as semaglutide acetate or semaglutide sodium, are not FDA approved, have not undergone clinical trials, and have not been proven to be safe and effective. It is highly advisable not to use these products.

When buying this product, always ensure that it is in the base form and does not contain a salt form of the drug.

Is compounded semaglutide the same as Ozempic?

Compounded semaglutide treatment contains the same active ingredient as the brand names, Ozempic and Wegovy. While it is identical to the brand name (e.g. it comes in a vial instead of a prefilled pen), it is intended to act in your body the same way and provide the same benefits.

One benefit of compounded medications is that you will pay a significantly lower price, up to 75% lower than the brand name cost.

What is the dosing for compound semaglutide?

The dosing for compound semaglutide varies by the formulation provided by the compounding pharmacy, and the healthcare provider that prescribes the medication.

As an example, this is the dosing plan that a patient may expect when starting to take compound semaglutide injectable medication:

  • Month 1 (weeks 1-4): 10 units (0.25mg) per week
  • Month 2 (weeks 5-8): 20 units (0.5mg) per week
  • Month 3 (weeks 9-12): 40 units (1mg) per week
  • Month 4 (weeks 13+): 70 units (1.75mg) per week and maintain at this dose

Where do you inject compounded semaglutide?

Compounded semaglutide is administered subcutaneously (under the skin). Pinch the injection site and alternate injection sites between either side of the stomach (abdomen), back of the arm, or thigh. Inject approximately two inches from the belly button on either side.

How to get compounded semaglutide for weight loss

The NiceRx Weight Loss Program helps eligible patients receive a prescription online from a licensed U.S. clinician for compounded semaglutide (same active ingredient as Ozempic and Wegeovy) and compounded tirzepatide (same active ingredient as Mounjaro and Zepbound) at an affordable price.

If approved for a prescription, the medication is shipped directly to your home from a licensed U.S. compounding pharmacy.

The bottom line

Compounded semaglutide and tirzepatide are effective weight loss medications. These compounded medications are effective alternatives to the costly brand name drugs that many people cannot afford, especially without adequate insurance coverage.

You should avoid products that contain the salt form of the medication which are known to be potentially unsafe as the salt form of the drug is not FDA-approved and has not been studied in clinical trials.

If you are considering buying compounded semaglutide or tirzepatide, NiceRx can help you obtain a prescription (if appropriate) and supply the medication from a licensed U.S. compounding pharmacy.

When will Zepbound be available at U.S. pharmacies?

The release of Zepbound has been highly anticipated since the launch of the breakthrough type 2 diabetes medication Mounjaro, manufactured by the same U.S. pharmaceutical company, Eli Lilly and Company. Mounjaro and Zepbound have the same active ingredient, tirzepatide, while Zepbound was recently approved by the FDA (U.S. Food and Drug Administration) in 2023 as a chronic weight management prescription medication.

Zepbound is currently available in pharmacies throughout the United States. Learn more about Zepbound benefits, where to buy it, and money-saving options.

Zepbound benefits

Zepbound (tirzepatide) is an innovative injectable prescription medicine used along with diet and exercise for weight loss in adults with obesity and and at least one weight-related health condition.

Zepbound has not been studied in patients with a history of pancreatitis, or with severe gastrointestinal disease, including severe gastroparesis. Discussing your medical history with your healthcare providers is important, as these may be reasons to avoid the medication.

Following the U.S. Food and Drug Administration (FDA) approval on Nov. 8, 2023 , people with obesity can purchase Zepbound in the following six doses: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg, through a valid prescription that can be filled at a mail-order pharmacy or retail pharmacy.

In clinical trials, tirzepatide has proven to be more effective for weight loss compared to similar medications such as Ozempic and Wegovy.

Zepbound combines glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) to help regulate blood sugar levels that effectively promote weight loss.

Along with a reduced calorie diet and increased physical activity, Zepbound is FDA approved for weight loss and chronic weight management in:

  • adults who have obesity, which is defined as a BMI (body mass index) of 30 or more, or;
  • adults who are overweight, which is defined as a BMI of 27 or more in addition to at least one weight-related medical problems, such as high cholesterol, high blood pressure, obstructive sleep apnea, cardiovascular disease, or type 2 diabetes

Common side effects of Zepbound include nausea, vomiting, constipation, stomach (abdominal pain), injection site reactions, and stomach (abdominal) pain, although clinical trials have shown that these side effects will likely subdue with continued use once the body gets used to using the medication. Stop using Zepbound if you experience any serious allergic reactions and seek medical advice promptly from a healthcare professional.

Clinical trials

The superior efficacy of this medication has been demonstrated in clinical trials compared with other similar medications. Evidence from a 36-week SURMOUNT-4 clinical trial showed that patients taking tirzepatide experienced an initial mean weight reduction of 20.9% from a mean body weight of 236.6 lbs.

The clinical trial also demonstrated the overall safety of tirzepatide as reported in previous trials, with the most common side effect reported as gastro-related including nausea and other stomach-related problems.

Zepbound availability at U.S. pharmacies

Availability may change occasionally in different parts of the country as this medication is in high demand since it was FDA approved.

Is Zepbound available now?

Zepbound is available now for purchase at U.S. pharmacies with a prescription from a licensed U.S. healthcare provider.

Shortages

Shortages are expected with this newly FDA approved medication as has been the case with other new medications such as Mounjaro, Ozempic and Wegovy. “Unprecedented demand” is expected for Zepbound once it is launched.

Pharmacists, physicians, and patients have reported a strained supply of Zepbound, Lilly’s new weight-loss medication.

You can monitor the up to date list of medication shortages on the FDA Drug Shortages website.

How to save money on Zepbound

There are multiple options to save money on this weight loss drug. Check with your insurance company if they cover anti-obesity medications such as Zepbound and start exploring your options.

Savings cards

If you have commercial insurance coverage, you may be eligible for the Zepbound Savings Card and could possibly pay as low as $25.  The savings card is provided by the manufacturer, Eli Lilly.

Compounded tirzepatide

You can also consider buying compounded tirzepatide (the same active ingredient as Zepbound), available through the NiceRx Weight Loss Program.

The bottom line

As demonstrated in clinical trials, Zepbound is a superior weight loss medication in comparison to other medications on the market and is currently available at U.S. pharmacies, although shortages are expected due to strong demand from patients.

Stay updated with the latest availability of this medication. If you can’t purchase this medication due to shortages and the medication is on the FDA drug shortage list, consider purchasing the compounded version of tirzepatide or consult with healthcare professionals regarding alternative options that may be appropriate for you.

How to pay $25 using the Zepbound Savings Card: The Ultimate Guide

Zepbound (tirzepatide) is a prescription medication approved by the Food and Drug Administration (FDA) along with diet and exercise for weight loss and chronic weight management in adults with obesity or overweight with at least one other weight-related medical condition.

Obesity and overweight are serious medical conditions that affect millions of Americans and can be associated with some of the common causes of death such as diabetes, stroke, and heart disease.

The average retail list price for this medication is $1,050 per month without insurance coverage. With the Zepbound Savings Card program, eligible patients can pay as little as $25 for their prescription. Understanding the eligibility criteria and the application process is essential for taking advantage of these potential savings. However, not all patients, including those with government insurance, qualify for the savings card.

Who is eligible to get Zepbound for $25?

The Eli Lilly Zepbound Savings Card program is intended to significantly reduce the out-of-pocket costs for eligible patients with commercial drug insurance coverage.

Call your insurance company (the phone number on the back of your insurance card) or visit their website to find out if your commercial insurance plan covers Zepbound and ask them the following questions:

  • Does my insurance plan cover Zepbound?
  • If Zepbound is covered, how much will I pay? This will depend on your drug plan’s copay.
  • Does my doctor need to submit a prior authorization (PA) form?
  • What is my deductible (the out-of-pocket cost I need to pay before my insurance starts paying)?
  • Which pharmacies can I obtain the medication from?

Should your insurance provider deny coverage for this medication, appeal procedures are often available. Ask your insurance company about the appeal process. It may involve submitting additional documentation such as a letter of medical necessity for using Zepbound.

Commercial insurance with insurance coverage for Zepbound

Commercially insured patients with insurance coverage for Zepbound may pay as low as $25 for a 1-month or 3-month supply of Zepbound with the following limitations:

  • Maximum monthly savings of up to $150 for a 1-month prescription
  • Maximum monthly savings of up to $300 for a 2-month prescription
  • Maximum monthly savings of up to $450 for a 3-month prescription
  • Maximum annual savings of up to $1,800 per calendar year
  • Prescription can be filled up to 13 times per calendar year

Commercial insurance without insurance coverage for Zepbound

Commercially insured patients without insurance coverage for Zepbound may pay as low as $525 for a 1-month supply of Zepbound with the following limitations.

  • Maximum monthly savings of up to $563 for a 1-month prescription
  • Maximum annual savings of up to $7,319 per calendar year
  • Prescription can be filled up to 13 times per calendar year

Terms and conditions

  1. You have a prescription from a licensed U.S. prescriber according to the FDA-approved product labeling
  2. You are enrolled in a commercial drug insurance plan without coverage for Zepbound
  3. You are not enrolled in government insurance plans such as Medicare, Medicaid, Medicare Part D, Medicare Advantage, Medigap, VA, DoD, TRICARE/CHAMPUS, or any state drug assistance program
  4. You are a legal resident of the United States or Puerto Rico
  5. You are at least 18 years of age.

Once approved for the savings card, inform the pharmacist of your Savings Card when purchasing the medication. If eligible, the card’s benefits should be applied immediately, providing you with instant savings on the medication.

For those ineligible, exploring other financial assistance programs, alternative medications, or generic options, can potentially help you save money.

Who is not eligible for the Zepbound Savings Card

The Zepbound Savings Card is not available to:

  1. Individuals with government insurance: including Medicare, Medicaid, Medicare Part D, Medicare Advantage, Medigap, VA, DoD, TRICARE/CHAMPUS, or any state drug assistance program.
  2. Individuals without commercial drug insurance coverage
  3. Individuals residing in California or Massachusetts: due to state restrictions, this medication is not available to residents of California and Massachusetts.
  4. Individuals who are not residents of the United States or Puerto Rico
  5. Individuals without a valid prescription for an FDA-approved product labeling of Zepbound
  6. Individuals with an insurance plan that participates in an alternate funding program (“AFP”), for example, ImpaxRx, SHARx, Script Sourcing, etc. Eli Lilly may change the eligibility requirements and terms and conditions at any time, so it is advisable to check their website for the latest information.

Steps to access the Zepbound Savings Card

If you believe that you are eligible for the savings card, you can follow these steps:

  1. Go to the Zepbound Savings Card website
  2. Choose the type of health insurance plan you have
  3. Verify that you are eligible
  4. Download your savings card
  5. Go to a participating pharmacy with the Savings Card. Generally, Eli Lilly medicines are available from neighborhood pharmacies such as CVS, Walgreens, and specialty pharmacies.

If you encounter any issues or have questions during the application process, customer service representatives can assist and provide further guidance.

Alternative savings options

Even without the Zepbound Savings Card, there are other medication options to explore that may help reduce the cost of your weight loss drug.

Compounded tirzepatide for weight loss

Compounded tirzepatide has the same active ingredient as the brand-name prescription drug, Zepbound. Buy compounded tirzepatide by signing up for a NiceRx Weight Loss Program membership. A licensed provider will determine if this prescription drug is appropriate for you.

Alternative medications for weight loss

There are several alternative GLP-1 medications to consider. Speak with your healthcare professional to determine if any of these alternative options are appropriate for you:

Explore coverage for other insurance types

If you have government insurance that makes you ineligible for the Zepbound Savings Card, there may be other options for you to consider, depending on your insurance type.

I am enrolled in Medicaid

Coverage through Medicaid depends on the state you live in. Check your state’s Medicaid Preferred Drug List (PDL) to find out if Zepbound is covered.

I am enrolled in Medicare

Most Medicare plans do not cover anti-obesity medications such as Zepbound, except for some Medigap and Medicare Advantage plans. Contact your Medicare insurance provider’s customer service to check if Zepbound is covered.

I am enrolled in Veterans Affairs

Veterans Affairs may cover anti-obesity medications including Zepbound. Speak with your local Veterans Affairs provider to verify your coverage and options.

I am enrolled in government employee benefits

Speak with your insurance company if you are a city, state, federal municipality, or federal department government employee to determine your coverage options.

I am enrolled in TRICARE®

TRICARE® insurance may cover Zepbound and your healthcare provider can request a coverage review, which is the process that TRICARE® uses to determine if it will approve coverage. Speak with your TRICARE® provider or Military Treatment Facility regarding your options and coverage.

Prescription discount cards

Medication prices vary by pharmacy and you may find additional savings by using pharmacy comparison tools such as GoodRx or SingleCare which offer additional savings with prescription discount cards.

Common questions about Zepbound

Here are answers to some of the most common questions about Zepbound.

What is Zepbound?

Zepbound contains the active ingredient tirzepatide. It is an injectable prescription anti-obesity medication that is used for weight loss and should be used with a low-calorie diet and increased physical activity.

According to the manufacturer’s website, people taking Zepbound lost up to 48 lbs as evidenced in a 17-month clinical trial, with people who dieted, exercised and took the medication.

The Food and Drug Administration (FDA) has approved Zepbound along with diet and exercise for weight loss and weight management in adults with:

  • a BMI (body mass index) of 30 or more, or;
  • a BMI of 27 or more in addition to at least one weight-related condition, such as high cholesterol, high blood pressure, or type 2 diabetes

Who should not take Zepbound?

The manufacturer warns that Zepbound can cause tumors in the thyroid which includes thyroid cancer.

It is important to monitor possible symptoms while taking the medication. For example, a swelling or lump in the neck, shortness of breath, trouble swallowing, or hoarseness.

If you experience any of these symptoms while taking the medication, speak to your healthcare professional immediately.

  • Do not use this medication if you or any of your family have ever had a thyroid cancer that is called medullary thyroid carcinoma (MTC).
  • Do not use this medication if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • Do not use this medication if you have had a serious allergic reaction to this medication or any of the ingredients in this medication

What are Zepbound side effects?

Zepbound may cause serious side effects such as:

  • severe stomach problems
  • kidney problems (kidney failure)
  • inflammation of the pancreas (pancreatitis)
  • gallbladder problems
  • changes in vision in patients with diabetes type 2
  • low blood sugar (hypoglycemia)
  • depression
  • thoughts of suicide

Common side effects of this medication may include:

  • nausea
  • diarrhea
  • vomiting
  • stomach (abdominal) pain
  • constipation
  • indigestion
  • feeling tired
  • injection site reactions
  • belching
  • allergic reactions
  • heartburn
  • hair loss

If you experience any side effects or adverse reactions while using this medication, seek immediate medical advice from your healthcare provider.

What can I do if the Zepbound Savings Card is not working?

If your Zepbound Savings Card is not working:

  • look for instructions on the card or the paperwork that came with it
  • if online activation is available, visit the card activation website
  • follow the prompts

Alternatively, you can call the phone number listed on the card or the accompanying materials that you received with the savings card.

How much is Zepbound with the savings card?

The cost of Zepbound varies depending on your commercial insurance coverage and whether it covers Zepbound. If your commercial insurance covers Zepbound, you can pay as little as $25. If your commercial insurance does not cover Zepbound, you can pay as little as $525. Find out from your commercial insurance company if they cover this medication.

Is Zepbound covered by Medicare?

Most Medicare plans do not cover anti-obesity medications. However, some Medigap and Medicare Advantage plans cover anti-obesity medications such as Zepbound. Contact your Medicare insurance provider’s customer service to determine if Zepbound is covered.

The bottom line

Zepbound (tirzepatide) is an expensive drug without adequate insurance coverage. Fortunately, Eli Lilly offers eligible commercially insured patients effective options to reduce out-of-pocket expenses when using the Zepbound Savings Card. Savings cards and discount cards are effective ways to save money on expensive medications.

Even if you are ineligible for the Zepbound Savings Card, there are several other options to save money on your weight loss medication, including the compounded version of Zepbound that is available through the NiceRx Weight Loss Program.

Does Bydureon cause weight loss?

Bydureon BCise is a brand-name antidiabetic medication that is manufactured by AstraZeneca Pharmaceuticals. It is used to reduce blood sugar levels and improve HbA1c levels in certain patients with type 2 diabetes (T2DM).

Bydureon BCise is not approved as a weight loss medication but patients who take this medication may lose weight. Keep reading as we discuss Bydureon BCise and how much weight you can lose on this medication.

What is Bydureon BCise (exenatide)?

Bydureon BCise is a glucagon-like peptide-1 (GLP-1) receptor agonist that was initially approved by the United States Food and Drug Administration (FDA) in October 2017. It is an extended-release injectable suspension that is approved along with diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus (T2DM). It is not approved to treat type 1 diabetes mellitus (T1DM) or diabetic ketoacidosis. Bydureon BCise can be used alone or along with other antidiabetic medications such as sulfonylureas, thiazolidinediones, or metformin.

This medication should not be used as first-line treatment in T2DM patients who have uncontrolled blood glucose levels on diet and exercise. Bydureon BCise is an exenatide extended-release formulation. You should not use this medication with other products that contain exenatide, including Byetta.

GLP-1 agonists such as Bydureon Bcise are a type of incretin mimetic that works the same way as the GLP-1 hormone your body makes. Incretins help your body manage blood glucose levels and play a role in digestion. After binding to GLP-1 receptors in pancreatic beta cells, Bydureon BCise stimulates your pancreas to release insulin. It also decreases the release of glucagon, which is a hormone that increases your blood sugar and slows down how quickly your stomach moves food into your intestines.

Bydureon BCise is available as a 2 mg/0.85 ml extended-release injectable suspension in a single-dose autoinjector.

Does Bydureon BCise help with weight loss?

Bydureon BCise is approved to help manage blood glucose levels in patients with T2DM. There have not been any clinical studies on the use of Bydureon BCise as a weight loss medication, and it is not approved for this use. However, some patients taking Bydureon BCise have lost weight while on this medication. According to the package insert, clinical trials showed certain patients lost between almost 1kg (2.2 lbs) and 2.7kg (5.95 lbs). Patients also saw improvements in their systolic blood pressure, total cholesterol, LDL cholesterol, and triglycerides.

Bydureon BCise should be prescribed along with changes in your diet and exercise to help manage your T2DM. Any weight loss you may have could be due to your diet and exercise changes.

If you’re interested in taking a medication such as Bydureon BCise for weight loss, other GLP-1 agonists are approved for this use. Wegovy (semaglutide) and Saxenda (liraglutide) are both approved as weight loss drugs to treat obesity in certain people.

How do you use Bydureon BCise?

  • Use Bydureon BCise exactly as your doctor prescribes it to you. You should not change your dose or stop this medication without discussing it with them first.
  • Your doctor should demonstrate how to use Bydureon BCise before you give your first dose. Bydureon BCise can be injected subcutaneously (under the skin) in your stomach, thigh, or upper arm. Bydureon BCise should not be injected directly into your muscle or vein.
  • This medication is given once a week on the same day of each week. It can be administered at any time of the day with or without food. You can change the day of the week you administer Bydureon BCise if your last dose was given at least 3 days before.
  • Do not mix this medication and insulin in the same injection. You can administer them in the same area of the body as long as it is not right next to each other.
  • Rotate the injection site with each dose of Bydureon.

What should you do if you miss a dose of Bydureon BCise?

If you miss a dose of this medication, administer the missed dose immediately as long as there are at least 3 days until the next dose. If there are less than 3 days until your next dose, skip the missed dose and administer the next dose on its scheduled day. Two doses of Bydureon BCise should not be administered within 3 days of each other.

What should you tell your healthcare professional before starting Bydureon BCise?

Before taking Bydureon BCise, be sure your doctor is aware of all your medical conditions, including:

  • Kidney disease
  • Pancreas problems
  • Gastrointestinal problems
  • Personal or family history of medullary thyroid carcinoma, a type of thyroid cancer
  • Heart disease
  • Are pregnant, plan on becoming pregnant, or are breastfeeding

What are the most common side effects of Bydureon BCise?

The most common side effects seen in clinical trials include:

  • Injection site reactions such as nodules
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Constipation
  • Indigestion
  • Dizziness
  • Loss of appetite
  • Weight loss
  • Fatigue

Bydureon BCise can sometimes cause serious side effects such as:

  • Severe allergic reactions including anaphylaxis (hives, swelling of your tongue or throat, and trouble breathing)
  • Kidney problems or injury
  • Increased risk of thyroid tumors
  • Increased risk of multiple endocrine neoplasia syndrome type 2 (MEN 2), an endocrine system disorder
  • Hypoglycemia (low blood sugar), especially if taken with an insulin secretagogue or insulin
  • Major bleeding

Speak with your healthcare provider about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Bydureon BCise. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Which is better Ozempic (semaglutide) or Bydureon BCise (exenatide)?

Ozempic and Bydureon BCise are both GLP-1 receptor agonists that are used along with diet and exercise to manage glycemic control in adults with T2DM. They share some of the same side effects including constipation, diarrhea, vomiting, and nausea. They also share most of the same drug interactions including insulin or insulin secretagogues. Bydureon BCise also can interact with Coumadin (warfarin). They are both given as injections under the skin once a week. While Ozempic and Bydureon BCise have not been directly compared, Ozempic was compared to Bydureon before it was discontinued. In this clinical study, Ozempic lowered HbA1c levels by 1.4% while Bydureon lowered them by 0.9%. In the same study, Ozempic (62%) helped more patients reach their HbA1c goal of less than 7% than Bydureon (40%). Ozempic was also shown to help patients lose more weight than other diabetic medications. Patients taking Ozempic lost an average of 10.6 lbs (4.8 kg) while patients on Bydureon lost 4.4 lbs (2 kg).

What diabetes medication helps you lose weight?

While there are numerous diabetes medications that you may lose weight with while taking, there are only a few that are approved for weight management. Wegovy (semaglutide) and Saxenda (liraglutide) are both GLP-1 agonists that are FDA-approved for weight loss. Both medications are manufactured by the Danish pharmaceutical company NovoNordisk and are used along with diet and exercise.

Clinical trials with Saxenda showed an average weight loss of 8% for patients taking 3 mg daily for 68 weeks. Wegovy trials found significantly more weight loss. Patients given Wegovy 2.4 mg weekly lost an average of 15.8% of their body weight after 68 weeks.

There are also other GLP agonists being studied for this indication that doctors may use off-label to help you lose weight. Talk with them about the options available that might be right for you.

Why was Bydureon discontinued?

The original single-dose tray (SDT) formulation of Bydureon was discontinued on September 14, 2020, by AstraZeneca due to business reasons. It was not due to any safety or efficacy issues. It continues to produce Bydureon BCise, which contains the same dose of exenatide. It is available as an extended-release injectable suspension in a single-dose autoinjector.

How quickly does Bydureon BCise work?

Bydureon BCise will start lowering your blood sugar right after you inject your first dose. It takes time for it to build up in your body so it can take up to 10 weeks before you see Bydureon BCise’s full effects.

Does Trintellix cause weight gain?

More than 1 in 10 Americans take antidepressant drugs to treat depression. Like all medications, antidepressants such as Trintellix have side effects that can affect some, but not all people.

Weight gain is a possible side effect of many antidepressants. Weight change (weight gain or weight loss) is common in people with depression and other mood disorders even if they are not taking an antidepressant.

Keep reading as we discuss Trintellix and what effect it can have on your weight.

What is Trintellix (vortioxetine)?

Trintellix is an antidepressant medication that can be considered a serotonin modulator and stimulator. Trintellix was previously marketed under the brand name Brintellix but the manufacturer changed the name in 2016 after there was confusion between Brintellix and a prescription medication for the heart called Brilinta. Trintellix is FDA-approved to treat major depressive disorder (MDD) in adults.

The exact mechanism of action of Trintellix in the treatment of depression is not known but is thought to be due to its serotonergic activity and inhibition of the serotonin transporter, a mechanism similar to the selective serotonin reuptake inhibitors (SSRIs) such as Celexa (citalopram), Lexapro (escitalopram), Zoloft (sertraline), and Prozac (fluoxetine).

Trintellix is an oral tablet that is typically taken once a day. It is available in strengths of 5mg, 10mg, and 20 mg.

RELATED: What is Trintellix

Does Trintellix cause weight gain?

According to the drug manufacturer, Trintellix did not cause any significant change in body weight during short-term clinical studies or during a 6-month phase of a long-term study of patients who responded to Trintellix when compared to patients taking a placebo. However, since it has come out on the market, there have been reports of weight gain. It should be noted that it is unclear how often this occurs or if Trintellix was the cause of the weight gain.

If Trintellix is the cause, it may be due to Trintellix increasing your appetite or because it has altered your hormones or metabolism. Weight gain seems to be a rare occurrence with Trintellix, especially when compared to these other medications used to treat depressive symptoms due to mental health disorders, including:

  • Tricyclic antidepressants (TCAs) such as Elavil (amitriptyline), Tofranil (imipramine), and Sinequan (doxepin)
  • Monoamine oxidase inhibitors (MAOIs), such as Nardil (phenelzine)
  • Selective serotonin reuptake inhibitors (SSRIs) such as Zoloft (sertraline) and Paxil (paroxetine)
  • Atypical antidepressants such as Remeron (mirtazapine)

Other antidepressants that have been associated with less weight gain than those mentioned above, include Trintellix as well as:

  • Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as Cymbalta (duloxetine), Effexor (venlafaxine), Pristiq (desvenlafaxine), and Fetzima (levomilnacipran)
  • Wellbutrin (bupropion), an atypical antidepressant
  • Lexapro (citalopram), an SSRI
  • Serzone (nefazodone), an SSRI/antagonist
  • Viibryd (vilazodone), an SSRI/5HT-1A partial agonist

Just because you gain weight after starting an antidepressant, it does not mean it is an adverse effect of the medication. There are other factors that may contribute to you gaining weight after being prescribed an antidepressant such as Trintellix.

Depression itself can make gain weight by causing you to overeat, make poor diet choices, and keep you unmotivated to exercise. Depression can cause some people to have a decreased appetite, leading to weight loss. Starting an antidepressant can help improve your mood which can increase your appetite and result in weight gain.

Adults typically gain weight as they age, no matter what medications they are taking. Weight gain could also be due to bloating, constipation, or social eating.

What are the pros and cons of Trintellix?

If your prescribing physician has given you Trintellix to treat your depression, it is important to weigh the pros and cons of using this medication.

Pros

  • Trintellix is an oral tablet that you only have to take once a day
  • Is as effective and safe as SSRIs
  • May cause less sexual dysfunction and weight gain when compared to other medications for depression
  • Can be used when you have failed other antidepressants
  • May start to work faster than other typical antidepressants

Cons

  • Like other antidepressants, Trintellix may increase the risk of suicidal thoughts in patients under 24 years of age
  • It tends to cause nausea more frequently than other antidepressants
  • It can cause serotonin syndrome (agitation, rapid heartbeat, change in blood pressure, dizziness, fever, muscle stiffness, sweating, nausea, and vomiting) especially if it is combined with other medications or supplements that increase serotonin
  • Trintellix increases your risk of bleeding problems and low sodium (hyponatremia)
  • This medication may worsen mania symptoms or activate mania/hypomania if you have bipolar disorder

How do you take Trintellix?

Trintellix is an oral tablet that is typically taken once a day. You can take this medication with or without food. Make sure you take Trintellix exactly as your healthcare provider tells you to. Do not change your dose or stop taking this medication without talking with them first.

What should you tell your doctor before starting Trintellix?

Before taking Trintellix, be sure your doctor is aware of all your medical conditions, including:

  • History of seizures or convulsions
  • Bleeding disorder or are currently taking blood thinners such as Coumadin (warfarin)
  • Personal or family history of bipolar disorder, mania, or hypomania
  • Have low sodium levels
  • Glaucoma
  • Are pregnant or plan on becoming pregnant as Trintellix may harm your unborn baby
  • Are breastfeeding or plan to breastfeed

What are the most common side effects of Trintellix?

The most common side effects of Trintellix seen in clinical trials include:

  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Fatigue
  • Dizziness
  • Dry mouth
  • Gas
  • Abnormal dreams

Trintellix can sometimes cause serious side effects such as:

  • Serious hypersensitivity reactions, including anaphylaxis
  • Increased risk of suicidal thoughts and behaviors
  • Serotonin syndrome
  • Sexual side effects, including erectile dysfunction
  • Very low sodium levels

Speak with your healthcare provider about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Trintellix. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Trintellix side effects and how to avoid them

How much does Trintellix cost?

The estimated cost for #30 Trintellix 10mg tablets (30-day supply) is over $525 without insurance.

Why is Trintellix so expensive?

Brand-name medications such as Trintellix are typically more expensive because of the high costs to develop, market, and sell brand-new drugs. The drug companies that develop new medications will have a patent on them. This gives them the exclusive right to sell that medication. With no competition from generics, drug companies charge whatever the market will allow, maximizing their profits. The patents for Trintellix will expire in June 2027, which is the earliest date a generic pharmaceutical company will be able to apply for FDA authorization to sell a generic version of Trintellix.

RELATED: Why is Trintellix so expensive?

How long does it take Trintellix to work?

In short-term studies that lasted 6 to 8 weeks, patients started seeing the therapeutic effect of Trintellix in week 2 of treatment. The full effects of Trintellix are not typically seen until week 4 or later.

Does Trintellix make you retain water?

For some people who take Trintellix, it can cause them to have low sodium levels in their blood. Low sodium levels may be due to them retaining water and diluting the concentration of sodium. For those on Trintellix, it is typically due to fluid retention caused by the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Elderly patients over the age of 65 and those taking diuretics are at an increased risk of this side effect.

Dexilant and alcohol: can they be mixed together?

Alcohol can cause drug interactions when taken along with certain medications. Drinking alcohol can also worsen the condition you are treating.

Dexilant is a brand-name medication that decreases stomach acid in patients with GERD. The use of alcohol with Dexilant is generally not recommended.

Drinking alcohol may increase the amount of acid your stomach produces, which can worsen the symptoms of GERD. If you drink alcohol, talk to your healthcare professional about the amount that’s safe for you to have while you’re taking Dexilant.

Read on to find out about how Dexilant works and what can happen if you mix it with alcohol.

What is Dexilant (dexlansoprazole) used for?

Dexilant is a prescription medication that is manufactured by Takeda Pharmaceuticals. It is FDA-approved to:

  • Heal acid-related damage to the lining of your esophagus (erosive esophagitis)
  • Manage healed erosive esophagus and the relief of heartburn
  • Treat gastroesophageal reflux disease (GERD)

The active ingredient in Dexialnt is dexlansoprazole. It is the R-enantiomer of Prevacid (lansoprazole). Dexilant is classified as a proton pump inhibitor (PPI) and is used in adults and pediatric patients 12 years of age and older. It works by attaching to proteins in the cells of your stomach called H+/K+-ATPases that increase acid secretion. By attaching to these proteins, PPIs block them from working. This leads to a decreased amount of acid in your stomach, which can help prevent acid reflux and damage to your esophagus.

Dexilant is a delayed-release capsule that is typically taken once a day with or without food. Dexilant capsules should be swallowed whole. Its active ingredient is released in two phases at different pH values and with a time interval. This helps it inhibit acid secretion for a longer period when compared to other PPIs.

If you have trouble swallowing Dexilant capsules, you can open the capsule and sprinkle the intact granules on a tablespoonful of applesauce. You should then swallow the mixture immediately without chewing. Do not save the mixture to be taken at a later time.

If you miss a dose of Dexilant, take it as soon as you remember. If it is almost time for the next scheduled, skip the missed dose and take the next dose at its regular time. Do not take extra doses of Dexilant to make up for a missed dose.

RELATED: What is Dexilant

Can I drink alcohol while taking Dexilant?

There are no interactions between the use of Dexilant and alcohol. However, drinking alcohol may trigger acid reflux or worsen your symptoms. It is not known exactly how alcohol can cause or worsen GERD symptoms but it is thought it can:

  • Irritate and cause inflammation of your stomach
  • Cause your lower esophageal sphincter not to work properly
  • Cause increased urination

After ingestion, alcohol will irritate the lining of your stomach and cause inflammation. Long-term inflammation can cause cell death and permanent damage to your stomach and esophagus. This can cause an increased risk of gastritis or ulcers.

Drinking alcohol can also impair the muscle located at the junction of your esophagus and stomach called the lower esophageal sphincter (LES). By blocking its ability to close, it can allow stomach acid to flow back up into your esophagus, causing irritation and damage.

Alcohol is a diuretic, which makes you urinate more often. Increased urination can lead to dehydration, which can worsen symptoms of GERD.

While alcohol is thought to contribute to symptoms of GERD, it will affect people differently. If you already suffer from GERD, you should avoid drinking alcohol. Chronic alcohol consumption can lead to long-term complications, regardless if you have GERD or not. Contact your doctor for medical advice about the risks of drinking alcohol with your current medications and medical conditions.

What should you tell your doctor before starting Dexilant?

Before starting this medication, make sure your doctor is aware of your medical conditions, including:

  • Low magnesium, calcium, potassium, or sodium levels
  • Liver problems
  • Are taking a diuretic
  • Osteoporosis
  • Are pregnant, plan on becoming pregnant because based on animal data, Dexilant may cause adverse effects on bone growth and development of your unborn baby
  • Are breastfeeding as it is not known if Dexilant is found in breast milk

What are the side effects of Dexilant?

The most common side effects of Dexilant seen in clinical trials include:

  • Diarrhea
  • Stomach pain
  • Nausea
  • Upper respiratory tract infection
  • Vomiting
  • Gas
  • Headache
  • Constipation
  • Common cold symptoms
  • Weight gain

Dexilant can sometimes cause serious side effects such as:

  • Serious allergic reactions
  • Low vitamin B12 levels
  • Low magnesium levels (hypomagnesemia)
  • Stomach growths (polyps)
  • Increased risk of Clostridium difficile-associated diarrhea
  • Increased risk of bone fracture
  • Cutaneous and systemic lupus erythematosus (rash on the cheeks or other body parts, change in skin color, increased sensitivity to the sun, muscle or joint pain
  • Arrhythmia, bradycardia, or chest pain

Speak with your healthcare provider about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Dexilant. You should always seek medical advice for drug information or any questions about your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Dexilant side effects and how to avoid them

Does Dexilant cause weight gain?

Weight gain is not a common side effect of Dexilant, but it has been reported. It is more common in people who take it for a year or longer. It is not known why Dexilant may cause this interaction. You can offset any weight gain from Dexilant by making some lifestyle changes. Eating a healthy diet while getting regular exercise is the most effective way to maintain a healthy body weight while on Dexilant. Talk with your doctor about a diet and exercise plan that is right for you.

What does Dexilant interact with?

When taken with other medications, Dexilant can change how they work or increase the frequency and severity of side effects. You should ask your doctor if any of the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take may interact with this medication such as:

  • Antiretrovirals such as atazanavir, rilpivirine, or nelfinavir
  • Warfarin
  • Methotrexate
  • Digoxin
  • Tacrolimus
  • Ketoconazole
  • Itraconazole
  • St. John’s wort
  • Rifampin
  • Voriconazole

Can you drink coffee while taking Dexilant?

Caffeine, which is a major component of coffee, can be a possible trigger for heartburn in some people. It may trigger or worsen GERD symptoms because it can relax the lower esophageal sphincter. However, there are no well-designed studies that show the elimination of coffee or caffeine will improve your GERD symptoms or reduce complications. Most guidelines on managing GERD symptoms do not recommend eliminating caffeine from your diet.

How long does it take Dexilant to work?

Dexilant will start stopping acid production within a few hours of taking it. According to the package insert, clinical studies saw that 38% of patients taking Dexilant were heartburn-free after 3 days. However, as with all medications, your results can vary. Do not stop taking this medication if you do not see an improvement in symptoms. It may take up to 2 weeks before you see relief in your GERD symptoms. Contact your doctor if you have not seen symptom improvement after 2 weeks of Dexilant treatment.

Do you need to take Dexilant with food or without?

Dexilant can be taken with or without food. Dexilant capsules should be swallowed whole. If you cannot swallow the capsule whole, you can open it and pour its contents into a tablespoon of applesauce. You should then swallow the mixture without chewing. Do not save the mixture for future use.

Dexilant vs Prilosec (omeprazole)

Prilosec (omeprazole) and Dexilant (dexlansoprazole) are both PPIs used to treat erosive esophagitis, gastroesophageal reflux disease (GERD), and heartburn. They use the same mechanism of action way to reduce your production of stomach acid. It typically takes omeprazole around 30 minutes to work while it takes Dexilant 1 to 2 hours. While they have not been directly compared, they are both effective at reducing the production of stomach acid. Because Dexilant is released at two different points in your digestive tract and several hours apart, Dexilant may block acid production for a longer period than omeprazole.

Dexilant can be taken with or without food. Omeprazole needs to be taken on an empty stomach, as food can significantly decrease your body’s absorption of this medication. Dexilant typically causes fewer stomach problems, such as diarrhea.

There is a cost difference between omeprazole and Dexilant. Omeprazole will cost around $65 for #30, 20mg capsules. For#30 of generic Dexilant 60mg capsules, it will cost around $225. However, you can save on brand-name drugs like Dexilant through NiceRx if eligible for assistance.

Does Latuda cause weight gain?

Mental illnesses such as schizophrenia and bipolar disorder are associated with weight gain. Several factors can contribute to this, including lack of physical activity, unhealthy diet, genetics, and antipsychotic drugs.

Excessive weight gain and obesity can lead to heart disease, type 2 diabetes, and reduced quality of life. Most antipsychotic medications cause weight gain. The antipsychotics that have the highest risk of weight gain are Zyprexa (olanzapine) and Clozaril (clozapine).

It also appears that children and adolescents are at a higher risk of antipsychotic-induced weight gain. Latuda is generally considered to be weight-neutral. It may actually cause weight loss when taken long-term.

Read on to find out about how Latuda works and if it can cause you to gain weight while taking it.

What is Latuda (lurasidone)?

Latuda is a prescription medication that is manufactured by Sunovion Pharmaceuticals Inc. It is FDA-approved to treat mental health disorders such as:

  • Schizophrenia
  • Depressive episodes associated with bipolar I disorder (bipolar depression) as monotherapy
  • Depressive episodes associated with bipolar I disorder (bipolar depression) in adults when combined with lithium or valproate

Latuda isn’t approved to treat major depressive disorder with mixed features (agitated depression), but it is sometimes used off-label for this purpose.

The active ingredient of Latuda is lurasidone. It is classified as an atypical antipsychotic. Some other examples of atypical antipsychotics include Abilify (aripiprazole), Geodon (ziprasidone), Seroquel (quetiapine), Saphris (asenapine), and Risperdal (risperidone). It is not known exactly how atypical antipsychotics such as Latuda work. It is thought that Latuda reduces the positive and negative symptoms of schizophrenia because of its antagonist activity at dopamine-D2 receptors and serotonin 5-HT2A receptors. It may also be partly due to its partial agonist activity at serotonin 5-HT1A receptors.

Latuda is available as an oral tablet in strengths of 20mg, 40mg, 60mg, 80mg, and 120mg. It is typically taken once a day with food (at least 350 calories). Taking Latuda with food significantly increases the absorption of this medication. Your doctor will determine your dose of Latuda. It may need to be adjusted if you have liver or kidney impairment or if you are taking certain medications that can affect Latuda’s absorption and metabolism.

RELATED: What is Latuda?

What should you tell your doctor before starting Latuda?

Before starting this medication, make sure your doctor is aware of your medical conditions, including:

  • Heart disease or stroke
  • High or low blood pressure
  • Personal or family history of diabetes, metabolic syndrome, or high blood sugar
  • History of high cholesterol or triglycerides
  • High prolactin levels
  • Low white blood cell count
  • Seizure disorder
  • Kidney or liver disease
  • Are pregnant, plan on becoming pregnant because it may cause extrapyramidal and/or withdrawal symptoms to your baby if given during the third trimester
  • Are breastfeeding because it is not known if Latuda is found in breast milk

What are the most common side effects of Latuda?

The most common adverse effects of Latuda seen in clinical trials when compared to placebo include:

  • Drowsiness
  • Akathisia (feeling restless or having the urge to move)
  • Tardive dyskinesia (a movement disorder)
  • Parkinsonism
  • Nausea
  • Vomiting
  • Dry mouth
  • Increase in body weight (pediatric patients 10-17 years of age)
  • Insomnia
  • Agitation and anxiety
  • Dizziness
  • Increased blood pressure or heart rate
  • Increased blood glucose levels
  • Changes in lipids and triglycerides
  • Increased prolactin levels

Latuda can sometimes cause serious side effects such as:

  • Serious hypersensitivity reactions
  • Increased risk of death in elderly patients with dementia-related psychosis
  • Increased risk of suicidal thoughts or behaviors (notify your doctor of any new or worsening depression or suicidal thoughts and behaviors)
  • Neuroleptic malignant syndrome, especially if taken with antidepressants
  • Low white blood cell count

Speak with your healthcare provider about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Latuda. You should always seek medical advice for drug information or any questions about your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Latuda side effects and how to avoid them

Does Latuda cause weight gain?

People with schizophrenia, schizoaffective disorder, and bipolar disorder are at an increased risk of obesity when compared to the general population. Treatment of schizophrenia and bipolar disorder with Latuda is generally associated with a lower risk of weight gain than other antipsychotics. Short-term use of Latuda is known to have a minimal effect on body weight along with other antipsychotics such as Abilify (aripiprazole) and Geodon (ziprasidone).

A retrospective analysis of electronic health records looked at the long-term effect of Latuda on body weight. It showed that patients taking Latuda lost an average of 1.7 lbs (0.77 kg) after 12 months of treatment. The study also showed that patients who switched to Latuda from other antipsychotics that were at higher risk for weight gain lost an average of 3.7 lbs (1.68 kg).

So while short-term studies found that people taking Latuda may gain a small amount of weight, those who take it for at least a year typically see a small amount of weight loss.

Does Latuda affect your metabolism?

Like most other antipsychotic drugs, Latuda may cause metabolic changes and weight gain, especially in adolescents or if used short-term. It is typically less likely to cause weight gain than other antipsychotic medications. Latuda is also associated with minimal metabolic and weight change when used for at least a year.

Does Latuda or Abilify cause more weight gain?

A common side effect of most antipsychotics is weight gain. Atypical antipsychotics such as Latuda and Abilify are considered weight-neutral when compared to other antipsychotics. A 2021 retrospective study of over 15,000 adults being treated for schizophrenia looked at the effect of Latuda, Abilify, and other antipsychotics on body weight. It showed that Latuda was associated with the smallest proportion of patients with clinically relevant weight gain and the greatest proportion with clinically relevant weight loss.

Can you lose weight while on Latuda?

When used for at least 12 months, Latuda has been associated with a small amount of weight loss in patients with schizophrenia or bipolar disorder. Patients who switched to Latuda from a second-generation antipsychotic with medium to high risk for weight gain saw a greater amount of weight loss.

Will you lose weight after stopping Latuda?

If you have experienced weight gain with antipsychotics such as Latuda, you may have a significant but small reduction in weight after the discontinuation of treatment.

What medications does Latuda interact with?

When taken with other medications, Latuda can change how they work or increase the frequency and severity of side effects. You should ask your doctor if any of the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take may interact with this medication, such as:

  • Moderate CYP3A4 inhibitors such as diltiazem, atazanavir, erythromycin, fluconazole, and verapamil
  • Strong CYP3A4 inhibitors such as ketoconazole, clarithromycin, ritonavir, and voriconazole
  • Moderate CYP3A4 inducers such as efavirenz, etravirine, modafinil, and nafcillin
  • Strong CYP3A4 inducers such as rifampin, avasimibe, St. John’s wort, phenytoin, carbamazepine

How long does it take Latuda to work?

In the treatment of schizophrenia, it can take several weeks before you start to notice a significant improvement in symptoms. In the first 1 to 2 weeks, you should start to see improvements in symptoms such as hallucinations, disorganized thinking, delusions, motivation, and desire to be around other people. It can take 2 to 3 months before you see the full benefits of Latuda therapy.

Is Linzess generic available?

Linzess (linaclotide) is an expensive brand-name drug that currently has no generic version available. There are deals in place with its manufacturer for Mylan, Teva, and Sandoz to make generic versions of Linzess starting in 2029 and 2030.

Learn more about the earliest possible date for generic Linzess and options to save money on this medication.

What is Linzess (linaclotide)?

Linzess is a prescription medication that is manufactured through a partnership between Allergan and Ironwood Pharmaceuticals, Inc. It was initially approved by the United States Food and Drug Administration (FDA) in 2012 to treat:

Linzess is classified as a guanylate cyclase-C agonist (GC-C agonist). It binds to the GC-C receptor within the intestinal epithelium, which increases the fluid in your intestines. This moves food and waste through your gastrointestinal (GI) transit to increase bowel movements and relieve chronic constipation. In animal studies, Linzess also reduced stomach pain.

RELATED: What is Linzess?

What dosage forms and strengths of Linzess are available?

Linzess is available as an oral capsule in strengths of 72 mcg, 145 mcg, and 290 mcg.

RELATED: Linzess dosage

Are there cheaper alternatives to Linzess?

There are other FDA-approved prescription medications your healthcare provider can prescribe for you if you cannot take Linzess. These medications have different strengths, dosages, and indications.

Drug nameApproved usesSide effectsGeneric available
Trulance (plecanatide)IBS-C, chronic idiopathic constipationDiarrhea, stomach pain, gas
Amitiza (lubiprostone)IBS-C, chronic idiopathic constipation, opioid-induced constipationNausea, diarrhea, headacheYes
Ibsrela (tenapanor)IBS-CDiarrhea, gas, dizziness
Motegrity (prucalopride)Chronic idiopathic constipationHeadache, stomach pain, diarrheaf

RELATED: Linzess alternatives: which other medications can I take?

What drug is comparable to Linzess?

If Linzess does not work for you, Trulance (plecanatide) is another medication that belongs to the same drug class as Linzess. If you can’t take Linzess because you had serious adverse effects such as an allergic reaction, you should not take Trulance as you could have the same reaction. Trulance is an oral tablet you typically take once a day to treat IBS-C and CIC. It is contraindicated in patients under 6 years of age and should be avoided in patients under 18 years of age. Trulance’s main side effect is diarrhea. Like Linzess, there is no generic drug alternative available for it. The cost of Trulance without insurance is around $575, which is comparable to Linzess. Talk with your healthcare professional to find out if Trulance could be the right medication for you.

Is there a generic version of Linzess (linaclotide)?

No, there is currently no generic available for Linzess.

Allergan and Ironwood Pharmaceuticals have agreed to license generic versions of Linzess starting in 2029. Teva has a license to market generic Linzess in strengths of 145 mcg and 290 mcg in the United States starting March 31, 2029. Their agreement does not include the 72 mcg strength. Sandoz also reached a settlement to market its generic version of the 145 mcg and 290 mcg strengths in the U.S. starting in February of 2030. Mylan can begin producing its generic version in strengths of 145 mcg and 290 mcg in the U.S. starting February 5, 2030, and 72 mcg starting August 5, 2030. These are all subject to approval by the FDA.

When will the patent for Linzess expire?

The patent for Linzess will expire on August 11, 2031. However, the manufacturer has agreed with multiple generic companies to start producing generic Linzess starting March 31, 2029.

How do you take Linzess?

  • Take Linzess exactly as your healthcare provider prescribes it to you. Do not change your dose or stop taking this medication without discussing it with them first.
  • Linzess is typically taken once a day on an empty stomach, at least 30 minutes before the first meal of the day.
  • If you miss a dose of Linzess, skip the missed dose and take your next dose at the scheduled time. Do not take extra doses or 2 doses at the same time to make up for a missed dose.
  • You should swallow the Linzess capsule whole without crushing or chewing them. If you have problems swallowing Linzess capsules whole, you can open the capsule and sprinkle the beads over room-temperature applesauce. You can also mix Linzess beads with bottled water. You should swallow the mixture completely without chewing. You need to wait at least 30 minutes before eating if you take Linzess mixed with applesauce or water.

What should you tell your doctor before starting Linzess?

You should not take Linzess if you have had an allergic reaction to lubiprostone or any of the inactive ingredients in its formulation. You should also avoid this medication if you have a GI obstruction. Make sure your doctor is also aware if you are pregnant, plan on becoming pregnant, or are breastfeeding.

Linzess side effects

The most common side effects of Linzess seen in clinical trials include:

  • Diarrhea
  • Abdominal pain
  • Flatulence (gas)
  • Bloating
  • Headache
  • Vomiting
  • Upper respiratory tract infection
  • Sinusitis

Linzess can sometimes cause serious side effects such as:

  • Severe hypersensitivity reactions, including hives, swelling of your throat or tongue, and shortness of breath
  • Severe diarrhea, which can lead to serious dehydration

Speak with your prescribing doctor about the possible drug interactions with any other prescription drugs, over-the-counter products, supplements and vitamins you are taking. These are not all of the possible side effects of Linzess. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Linzess side effects and how to avoid them

Is Linzess dangerous?

Linzess is typically well tolerated and safe when taken as prescribed. However, it can cause some serious adverse effects. The use of Linzess in animal studies led to severe dehydration and death in some babies. For that reason, Linzess should be avoided in children 2 years of age and younger. Linzess can also cause severe diarrhea, which can lead to life-threatening dehydration. You should be sure to drink plenty of fluids while taking Linzess to help reduce your risk of dehydration. Stop using this medication and seek immediate medical attention if you develop abdominal pain, severe diarrhea, fainting, or bright red or black tar stool.

What is the price of Linzess?

Linzess is an expensive medication that has no generic version available. If you have prescription drug insurance, the cost of Linzess may vary depending on the coverage provided by your healthcare plan. To find out what you may need to pay, your insurance provider or pharmacist should be able to calculate your copay with your current insurance. The average retail price of Linzess without insurance is over $580.

How much does Linzess cost at Walmart?

The average 12-month retail price of Linzess at Walmart is $557 without insurance.

Why is Linzess so expensive?

With no generic available, Linzess has no competition to help lower the price. Once approved by the FDA, generic drugs typically cost about 80% to 85% less than their branded drugs.

RELATED: Why is Linzess so expensive?

Is Linzess covered by insurance?

According to the pharmaceutical manufacturer, 82% of patients are not required to take an OTC medication before receiving Linzess. It is considered a preferred or covered brand in 10 out of 10 top commercial insurance plans and 7 out of 7 top Medicare Part D plans.

Is Linzess available over the counter?

No, Linzess is not available over the counter and will require a prescription from your doctor. There are several laxatives that you can get over the counter before seeing your doctor if you have constipation, including Miralax (polyethylene glycol), Dulcolax (bisacodyl), and Senokot (senna).

Is Jardiance generic available?

Jardiance is an oral diabetes medication manufactured by Boehringer Ingelheim Pharmaceuticals, Inc. that was approved by the United States Food and Drug Administration (FDA) in 2014. It is classified as a sodium-glucose co-transporter 2 (SGLT-2) inhibitor. SGLT-2 inhibitors are sometimes referred to as “flozins” or “gliflozins” because of the common ending in the generic names of this class.

Currently, there is currently no generic version of Jardiance available. It is not known when the first generic version of Jardiance will become available but based on the patents and regulatory protections it appears that the earliest date for generic entry will be Feb. 24, 2025. Learn more about the earliest potential release date for generic Jardiance and options to save money on this medication.

What is Jardiance (empagliflozin)?

Jardiance is an SGLT-2 inhibitor that is FDA-approved to:

  • Reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure.
  • Reduce the risk of cardiovascular death from heart attack and stroke in adults with type 2 diabetes mellitus (T2DM) and cardiovascular disease.
  • Improve blood sugar levels along with diet and exercise in adults with T2DM

Jardiance should not be used if you have type 1 diabetes mellitus (T1DM) as it can increase your risk of diabetic ketoacidosis (increased ketones in your blood or urine). It should also be avoided if you have chronic kidney disease (CKD) and are on dialysis.

Jardiance works by inhibiting the transporter (SGLT-2) that is responsible for reabsorbing the majority of glucose filtered by your kidney. By inhibiting SGLT-2, Jardiance decreases the amount of glucose that is reabsorbed and increases the amount that is excreted out through your urine.

RELATED: What is Jardiance?

What dosage forms and strengths are available for Jardiance?

  • 10 mg tablet
  • 25 mg tablet

RELATED: Jardiance Dosage

Is there a cheaper alternative to Jardiance?

There are several other prescription medications you can take to help improve your glycemic control if you cannot take Jardiance. These medications have different strengths, dosages, and indications.

Drug nameApproved usesSide effectsGeneric available
Invokana (canagliflozin)Type 2 diabetesVaginal infections, UTIs, male genital infections
Invokamet (canagliflozin/metformin)Type 2 diabetesVaginal infections, diarrhea, nausea
Invokamet XR (canagliflozin/metformin)Type 2 diabetesVaginal infections, diarrhea, nausea
Farxiga (dapagliflozin)Type 2 diabetesVaginal infections, back pain, UTIs
Xigduo XR (dapagliflozin/metformin)Type 2 diabetesVaginal infections, diarrhea, UTIs
Qtern (dapagliflozin/saxagliptan)Type 2 diabetesUpper respiratory infection, UTIs, headache
Synjardy (empagliflozin/metformin)Type 2 diabetesUTIs, low vitamin B12 levels, increased cholesterol
Synjardy XR (empagliflozin/metformin)Type 2 diabetesUTIs, low vitamin B12 levels, increased cholesterol
Glyxambi (empagliflozin/linagliptin)Type 2 diabetesUTIs, respiratory tract infection, increased cholesterol
Steglatro (ertugliflozin)Type 2 diabetesVaginal infections, UTIs, male genital infections
Segluromet (ertugliflozin/metformin)Type 2 diabetesVaginal infections, UTIs, male genital infections
Steglujan (ertugliflozin/sitagliptin)Type 2 diabetesVaginal infections, UTIs, male genital infections
Glucophage (metformin)Type 2 diabetesNausea, vomiting, diarrheaYes
Victoza (liraglutide)Type 2 diabetesNausea, vomiting, diarrhea
Trulicity (dulaglutide)Type 2 diabetesNausea, diarrhea, increased liver enzymes
Adlyxin (lixisenatide)Type 2 diabetesNausea, vomiting, low blood sugar
Byetta (exenatide)Type 2 diabetesNausea, vomiting, injection site reaction
Bydureon BCise (exenatide)Type 2 diabetesNausea, headache, injection site reaction
Tanzeum (albiglutide)Type 2 diabetesNausea, vomiting, injection site reaction
Mounjaro (tirzepatide)Type 2 diabetesNausea, diarrhea, decreased appetite
Rybelsus (semaglutide)Type 2 diabetesNausea, vomiting, diarrhea

Is there a generic available for Jardiance?

No, currently there is no generic version of Jardiance available. However, you can save on brand-name drugs like Jardiance through NiceRx if eligible for assistance.

When will generic Jardiance become available?

The exact date when a generic of Jardiance will be released is not known. However, the drug patents for Jardiance are expected to expire in February 2025, which is the earliest a Jardiance generic could become available for sale. This may change due to patent challenges or generic licensing by the drug manufacturer.

How do you take Jardiance?

Jardiance is an oral diabetes medicine that is used with a proper diet and exercise program to control high blood sugar in people with T2DM. It is a tablet that is taken by mouth once in the morning each day, with or without food. Your doctor may adjust your dose based on your blood glucose levels. You should not change your dose or stop taking this medication without discussing it with them first. If you miss a dose of Jardiance, take it as soon as you remember. If it is almost time for your next dose, skip the dose you missed and go back to your regular schedule. Do not take extra doses of Jardiance to make up for a missed dose.

What should you tell your doctor before starting Jardiance?

You should not take this medication if you have a hypersensitivity to empagliflozin or any of the inactive ingredients in Jardiance or if you are on dialysis.

You should take Jardiance with caution if you have certain medical conditions, including:

  • Heart disease or low blood pressure (hypotension)
  • Kidney problems or decreased kidney function
  • Liver problems
  • History of infection of the penis or vagina
  • History of urinary tract infections
  • Scheduled surgery
  • Change in diet or amount of food you are eating
  • Problems with your pancreas or pancreatic surgery
  • Are a chronic alcohol drinker or you binge drink
  • Type 1 diabetes
  • Are currently pregnant or are planning on becoming pregnant as this medication may harm your unborn baby
  • Are  currently breastfeeding or planning to breastfeed

Jardiance side effects

The most common side effects of Jardiance seen in clinical trials include:

  • Urinary tract infections (UTIs)
  • Yeast infections
  • Upper respiratory tract infection
  • Increased cholesterol
  • Increased urination
  • Male genital yeast or fungal infections
  • Nausea
  • Weight loss
  • Joint pain
  • Dizziness or lightheadedness

Jardiance can sometimes cause serious side effects such as:

  • Serious allergic reactions including life-threatening anaphylaxis (hives, swelling of the throat or tongue, and trouble breathing)
  • Low blood sugar (hypoglycemia), especially if taken with a sulfonylurea
  • Kidney problems
  • Volume depletion, especially in patients with reduced kidney function, elderly patients, or patients on loop diuretics (water pills)

Speak with your healthcare professional about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Jardiance. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Jardiance side effects and how to avoid them

What is the average monthly cost of Jardiance?

The estimated cost for #30 (30-day supply) tablets of Jardiance 10mg is almost $700 without insurance.

How long does it take Jardiance to work?

According to the drug manufacturer, it can take up to 24 weeks before you see results with Jardiance, so it’s important to take it daily. As with all medications, your results may vary.

What is the difference between Jardiance and Invokana?

Jardiance and Invokana are both used along with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Jardiance is also approved to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus or heart failure. Both medications are classified as SGLT 2 inhibitors that are taken by mouth once a day. They both commonly cause side effects such as vaginal yeast infection, genital yeast infection in men, and increased cholesterol levels. While they have not been compared directly, both medications have been shown to be effective in lowering HbA1c levels, fasting and postprandial (after a meal) glucose levels, weight, and systolic blood pressure.

What drug is comparable to Jardiance?

There are a number of medications available to manage a diagnosis of type 2 diabetes mellitus if Jardiance is not the right medication for you. These medications should be used along with a diet and exercise program developed by your doctor or diabetes care team.

Some alternative oral medications that your doctor may prescribe include:

  • Invokana (canagliflozin), an oral tablet taken once a day
  • Farxiga (dapagliflozin), an oral tablet taken once a day
  • Steglatro (ertugliflozin), an oral tablet taken once a day
  • Glucophage (metformin), an oral tablet taken up to 3 times a day
  • Tradjenta (linagliptin), an oral tablet taken once a day

Is Advair generic available?

Advair (fluticasone/salmeterol) is a combination asthma medication that is manufactured by GlaxoSmithKline (GSK). This brand-name drug was initially approved by the United States Food and Drug Administration (FDA) in 2000.

Currently, there are a few drug manufacturers that make a generic version of Advair Diskus. Wixela Inhub was the first generic version of Advair Diskus that Mylan brought to the market in 2019. Since then, Hikma Pharmaceuticals and Teva Pharmaceuticals have released their own generic version of Advair Diskus.

Learn more about Advair Diskus, Wixella Inhub, and what alternative options are available for asthma patients to save money.

What is Advair?

Advair is a combination product that contains an inhaled corticosteroid (fluticasone propionate) and a long-acting beta-agonist or LABA (salmeterol xinafoate). The corticosteroid fluticasone propionate helps reduce inflammation in your lungs while the long-acting beta-agonist (LABA) salmeterol xinafoate relaxes the smooth muscle in your lungs to help open your airways so you can breathe easier. It is approved for the:

  • Treatment of asthma in patients aged 4 years of age and older
  • Maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, to improve breathing and reduce flare-ups

Advair should not be used to relieve sudden breathing problems. You should always carry a rescue inhaler with you to treat an asthma attack. If you do not have a rescue inhaler, call your doctor to have one prescribed for you.

What dosage forms and strengths of Advair and its generics are available?

Advair Diskus and its generic equivalents are available with a combination of 100 mcg, 250 mcg, or 500 mcg of fluticasone propionate and 50 mcg of salmeterol inhalation powder.

It is also available as an Advair HFA inhaler with a combination of 45 mcg, 115 mcg, or 230 mcg of fluticasone propionate and 21 mcg of salmeterol per actuation.

Are there cheaper alternatives to Advair?

There are other prescription medications your healthcare provider can prescribe for you cannot use Advair. These medications have different strengths, dosages, and indications.

Drug nameApproved usesSide effectsGeneric available
Wixela Inhub (salmeterol/fluticasone)Asthma, COPDRespiratory tract infection, headache, sore throat
Airduo RespiClick (salmeterol/fluticasone)Asthma, COPDRespiratory tract infection, headache, sore throat
Advair HFA (salmeterol/fluticasone)Asthma, COPDRespiratory tract infection, headache, sore throat
Symbicort (formoterol/budesoonide)Asthma, COPDRespiratory tract infection, common cold, headacheYes
Combivent Respimat (albuterol/ipratropium)Asthma, COPDBronchitis, respiratory tract infection, headache
Anoro Ellipta (umeclidinium/vilanterol)COPDSore throat, diarrhea
Breo Ellipta (vilanterol/fluticasoone)Asthma, COPDRespiratory tract infection, common cold, headache
Bevespi Aerosphere (glycopyrrolate/formoterol)COPDCough, UTI, joint pain
Breztri (budesonide/formoterol/glycopyrrolate)COPDRespiratory tract infection, pneumonia, thrush
Dulera (mometasone/formoterol)AsthmaCommon cold, headache, sinusitis
Trelegy Ellipta (umeclidinium/vilanterol/fluticasone)Asthma, COPDHeadache, common cold, respiratory tract infection
Utibron Neohaler (indacterol/glycopyrrolate)COPDCommon cold, hypertension, back pain
Stiolto Respimat (tiotropium/olodaterol)COPDCommon cold, cough, back pain

RELATED: Advair alternatives for asthma and COPD

Is there a generic version of Advair?

Yes, there are currently several FDA-approved generic versions of Advair that are on the market. The first generic was approved under the brand name Wixela. There are now generic versions made by Hikma and Teva Pharmaceuticals. Generic drugs have the same active ingredients as the brand-name version and are generally considered to be as safe and effective as the original drug. Generics tend to cost less than the original version.

Is Wixela Inhub as good as Advair?

As an FDA-approved generic of Advair Diskus, Wixela Inhub is just as effective and safe. The active ingredients in Wixela Inhub and Advair Diskus are identical and have been demonstrated in clinical studies to help improve lung function. Wixela Inhub is available with the same strengths as Advair Diskus.

The average cost of #1 brand-name Advair Diskus 250mcg/50mcg inhaler is around $470, while the average cost of #1 Wixela Inhub 250mcg/50mcg inhaler is around $215.

When will generic Advair become available?

Currently, several generic versions of Advair are available:

  • Manufacturer: Mylan (under the name Wixela Inhub)
    Approval date: January 30, 2019
  • Manufacturer: Hikma Pharmaceuticals
    Approval date: December 17, 2020
  • Manufacturer: Teva Pharmaceuticals
    Approval date: December 13, 2021

How do you take Advair (salmeterol/fluticasone)?

  • Use Advair exactly as your doctor prescribes it to you. Do not change your dose or stop this medication without talking to them first.
  • Use 1 inhalation of Advair Diskus twice a day at the same time every day, around 12 hours apart. Rinse your mouth with water without swallowing after each inhalation to reduce throat irritation and lower your risk of developing thrush (yeast infection) in your throat or mouth.
  • If you miss a dose, just skip that dose and take the next dose at its regular time. Do not take extra doses or 2 doses at 1 time to make up for a missed dose.

What should you tell your doctor before starting Advair?

You should not take Advair if you have had an allergic reaction to salmeterol, fluticasone, or any of the inactive ingredients in Advair’s formulation. Advair should also be used with caution if you have certain medical conditions. You should tell make sure your doctor of all medical conditions you have, including:

  • Heart problems, including high blood pressure
  • Seizures
  • Thyroid problems
  • Diabetes
  • Liver problems
  • Have weak bones (osteoporosis)
  • Have a weakened immune system
  • Eye problems such as glaucoma, cataracts, or other changes in vision
  • Have an allergy to milk proteins
  • Have an active viral, bacterial, or fungal infection
  • Have been exposed to chickenpox or measles

Advair side effects

The most common side effects of Advair seen in clinical trials include:

  • Upper respiratory tract infection
  • Sore throat
  • Headache
  • Hoarseness
  • Thrush
  • Stomach pain
  • Upset stomach
  • Cough
  • Nausea
  • Vomiting
  • Diarrhea
  • Sinus infection

Advair can sometimes cause serious side effects such as:

  • Severe hypersensitivity reactions, including hives, swelling of your throat or tongue, and shortness of breath
  • Worsening of infections, including a potentially fatal course of chickenpox or measles
  • Osteoporosis
  • Glaucoma and cataracts
  • Increased blood pressure
  • Increased risk of seizures
  • Thyroid dysfunction

Speak with your prescribing doctor about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Advair. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Advair side effects and how to avoid them

What is the difference between Advair and Symbicort?

Symbicort and Advair are both combination medications that treat asthma and the symptoms of COPD. They both have a corticosteroid combined with a long-acting beta2-adrenergic agonist. Symbicort has a corticosteroid called budesonide while Advair contains fluticasone. They also each use a different long-acting beta2-adrenergic agonist. Symbicort uses formoterol and Advair uses salmeterol.

Symbicort is available as a metered dose inhaler. Advair comes as an HFA inhaler that is similar to Symbicort. Advair is also available as a powder for inhalation using a Diskus inhaler that doesn’t have a propellant to deliver the medication. You have to breathe in quickly and deeply to ensure the medication gets to your lungs.

Symbicort and Advair HFA can both be used in patients who are 12 years of age or older, while Advair Diskus is used in patients who are 4 years of age or older. They have a lot of the same side effects and drug interactions.

Symbicort and Advair Diskus both have generics available but are still expensive. The average cost of #1 generic Symbicort 160mcg/4.5mg inhaler is around $300 while #1 generic Advair Diskus 250mcg/50mcg inhaler is around $215.

RELATED: Symbicort vs Advair

Is there a generic for Advair HFA?

No, there is not a generic version of Advair HFA available in the United States. It is not known when a generic will be available.

Is Ozempic generic available?

Ozempic is a diabetes medication manufactured by Novo Nordisk Inc that was approved by the United States Food and Drug Administration (FDA) in 2017. It is classified as a glucagon-like peptide 1 (GLP-1) receptor agonist.

As of January 2023, there is currently no generic version of Ozempic available. It is not known when the first generic version of Ozempic will become available but based on the patents and regulatory protections, it appears that the earliest date for generic entry will be December 5, 2031.

Learn more about the earliest potential release date for generic Ozempic and options to save money on this medication.

What is Ozempic?

Ozempic (semaglutide) is a GLP-1 receptor agonist that is approved:

  • Along with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus (T2DM)
  • To reduce the risk of serious adverse cardiovascular events such as stroke and heart attacks in adults with T2DM and known heart disease

The safety and effectiveness of Ozempic have not been established in patients with pancreatitis and other diabetic treatment should be considered. This medication should not be used for the treatment of type 1 diabetes mellitus (T1DM).

RELATED: What is Ozempic

What dosage forms and strengths of Ozempic are available?

  • 2mg/3ml in a single-patient-use pen that delivers 0.25mg or 0.5mg per injection
  • 2mg/1.5ml in a single-patient-use pen that delivers 0.25mg or 0.5mg per injection
  • 4mg/3ml in a single-patient-use pen that delivers 1mg per injection
  • 8mg/3ml in a single-patient-use pen that delivers 2mg per injection

RELATED: Ozempic dosage

Are there cheaper alternatives to Ozempic?

There are other prescription medications you can take for blood sugar control if Ozempic is not right for you. These medications have different strengths, dosages, and indications.

Drug nameApproved usesSide effectsGeneric available
Glucophage (metformin)Type 2 diabetesNausea, vomiting, diarrheaX
Victoza (liraglutide)Type 2 diabetesNausea, vomiting, diarrhea
Trulicity (dulaglutide)Type 2 diabetesNausea, diarrhea, increased liver enzymes
Adlyxin (lixisenatide)Type 2 diabetesNausea, vomiting, low blood sugar
Byetta (exenatide)Type 2 diabetesNausea, vomiting, injection site reaction
Bydureon BCise (exenatide)Type 2 diabetesNausea, headache, injection site reaction
Tanzeum (albiglutide)Type 2 diabetesNausea, vomiting, injection site reaction
Mounjaro (tirzepatide)Type 2 diabetesNausea, diarrhea, decreased appetite
Rybelsus (semaglutide)Type 2 diabetesNausea, vomiting, diarrhea
Wegovy (semaglutide)Chronic weight managementNausea, vomiting, diarrhea

How much will the generic cost once it’s available?

As there are no generic alternatives currently on the market, it is impossible to estimate the price of generic Ozempic. However, the drug price of generics are typically much less expensive than brand-name medications, so you should expect to save money on Ozempic once the generic alternative is available for sale. The cost of generic Ozempic will vary based on the health insurance plan and copay you may have.

When will generic Ozempic become available?

It is not known the exact date when the generic of Ozempic will be released. However, the drug patents for Ozempic are expected to expire in December of 2031, which is the earliest an Ozempic generic could become available for sale. This may change due to patent challenges or generic licensing by the manufacturer.

How do you take Ozempic (semaglutide)?

  • You should use Ozempic exactly as your healthcare provider prescribes it to you. You should not change your dose or stop taking this medication without discussing it with them first.
  • Your healthcare provider will show you how to use Ozempic before you administer your first dose.
  • Ozempic is usually injected under the skin (subcutaneously) of your stomach, thigh, or upper arm. You should not inject this medication directly into a muscle (intramuscularly) or vein (intravenously).
  • Ozempic is typically given once a week, on the same day each week, at any time of the day. You can change the day of the week you take Ozempic if your last dose was administered 2 or more days before. You can take this medication with or without food.
  • If you miss a dose of this medication, take it as soon as you remember as long as it is within 5 days after your missed dose. If it has been more than 5 days since the missed dose, skip the missed dose and take the next dose on its regularly scheduled day.
  • You should not mix Ozempic and insulin in the same injection. You can inject Ozempic and insulin in the same body area, but not right next to each other.
  • Rotate your injection site each time you administer Ozempic. Don’t use the same site with each injection.
  • You should regularly check your blood glucose levels while on this medication. Your doctor should tell you how often to check your blood glucose and what your target glucose levels should be.
  • Stay on your prescribed diet and exercise program while using this medication.
  • Make sure you can recognize and manage symptoms of low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia). Symptoms of low blood sugar include rapid heartbeat, shaking, sweating, nervousness, irritability, dizziness, and hunger. Symptoms of high blood sugar include increased thirst, dry mouth, frequent urination, blurred vision, unintentional weight loss, and recurrent infections.
  • Your healthcare provider will monitor your diabetic treatment with regular blood tests, including your blood sugar levels and your hemoglobin A1C.

What should you tell your doctor before starting Ozempic?

You should not take Ozempic if you personal or family history of medullary thyroid carcinoma (MTC) or an endocrine system condition called multiple endocrine neoplasia syndrome type 2 (MEN 2). You should also avoid this medication if you have had an allergic reaction to semaglutide or any of the inactive ingredients in Ozempic.

Ozempic should also be used with caution if you have certain medical conditions. You should tell make sure your doctor of all medical conditions you have, including:

  • Pancreas problems
  • Kidney disease
  • History of diabetic retinopathy
  • Are pregnant, plan on becoming pregnant, or are breastfeeding

Ozempic side effects

The most common side effects of Ozempic seen in clinical trials include:

  • Nausea
  • Vomiting
  • Low blood sugar, especially if taken with a sulfonylurea
  • Diarrhea
  • Constipation
  • Stomach pain
  • Gas
  • Upset stomach
  • Headache
  • Fatigue

Ozempic can sometimes cause serious side effects such as:

  • Serious allergic reactions
  • Pancreatitis
  • Increased risk of thyroid tumors, including a type of thyroid C-cell tumor called medullary thyroid carcinoma (MTC)
  • Diabetic retinopathy
  • Acute kidney injury and worsening of chronic kidney failure
  • Gallbladder problems including gallstones
  • Increased heart rate

Speak with your prescribing doctor about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Ozempic. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Ozempic side effects

How long does it take Ozempic to work?

You should start to see a decline in your blood sugar levels within the first week of starting Ozempic at your regular maintenance dose. It may take up to 8 weeks or longer before you see the full effects of this medication.

How much does Ozempic cost?

The estimated cost for #1 prefilled Ozempic pen of 2mg/1.5ml is around $1,000 without insurance.

Why is Ozempic so expensive?

Ozempic is so expensive because it is a brand-name medication with no generic alternative available. Brand-name drugs are always more expensive than generic drugs. In contrast, the FDA-approved generic version of Ozempic will be much cheaper once it becomes available.

Is the generic Ozempic used for weight loss?

The active ingredient of Ozempic is semaglutide. It is used as a weight loss medication in the treatment of obesity under the brand name Wegovy. Wegovy works well for weight management when used along with a low-calorie diet and exercise. It can be used for adults and children 12 years and older with a certain body mass index (BMI).

RELATED: Ozempic for weight loss

Compounded Semaglutide is available through NiceRx. It is the compounded version of Ozempic and Wegovy.

Is Vyvanse generic available?

Vyvanse is an expensive ADHD medication that is manufactured by Takeda Pharmaceuticals. It was initially approved by the FDA in 2007 and the generic version of Vyvanse is available for sale.

What is Vyvanse?

Vyvanse is an extended-release central nervous system (CNS) stimulant that is classified as a Schedule II controlled substance. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of:

  • Attention deficit hyperactivity disorder (ADHD) in adult and pediatric patients 6 years of age and older
  • Moderate to severe binge eating disorder (BED) in adults

Vyvanse is not an approved weight loss drug. The use of other stimulant medications for weight loss has been associated with heart problems and other serious side effects. The safety and effectiveness of Vyvanse for the treatment of obesity have not been established.

The active ingredient in Vyvanse is lisdexamfetamine. Lisdexamfetamine is a prodrug, which is metabolized into L-lysine and dextroamphetamine once it is in the body. It is thought to work by stimulating the release of certain neurotransmitters such as dopamine and norepinephrine in the brain.

RELATED: What is Vyvanse?

Are there cheaper alternatives to Vyvanse?

There are other prescription medication alternatives to Vyvanse available for the treatment of ADHD. These medications have different strengths, dosages, and indications.

Drug nameApproved usesSide effectsGeneric available
Adderall (amphetamine/dextroamphetine)ADHD and narcolepsyLoss of appetite, headache, insomniaYes
Adderall XR (amphetamine/dextroamphetine)ADHD and narcolepsyLoss of appetite, headache, insomniaYes
Mydayis (amphetamine/dextroamphetine)ADHD and narcolepsyLoss of appetite, headache, insomniaYes
Concerta (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Ritalin (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Quillichew ER (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Qullivant XR (methylphenidate)ADHD and narcolepsyDecreased appetite, insomnia, stomach painYes
Focalin XR (dexmethylphenidate)ADHDStomach pain, headache, insomniaYes
Xelstrym (dextroamphetamine)ADHDDecreased appetite, insomnia, headacheNo
Intuniv (guanfacine)ADHDDry mouth, drowsiness, headacheYes
Strattera (atomoxetine)ADHDHeadache, stomach pain, decreased appetiteYes
Kapvay (clonidine)ADHDDry mouth, drowsiness, headacheYes

What is the closest drug to Vyvanse?

Is there a generic Lisdexamfetamine?

Yes, there is currently a generic version of Vyvanse (lisdexamfetamine) available.

How much will Vyvanse generic cost once it’s available?

Generic drugs are typically much less expensive than brand-name medications. The price of generic Vyvanse ranges by pharmacy and is estimated to cost between $50-200 per month, depending on where you buy it.

When will generic Vyvanse become available?

As of 2023, the generic version of Vyvanse is available for sale in the United States.  Patients who are taking this medication can start saving on this medication by purchasing the generic version of the drug.

How do you take Vyvanse (lisdexamfetamine)?

Vyvanse is a capsule or chewable tablet that is typically taken once a day in the morning with or without food. If you cannot swallow the capsule, open it and mix the contents with yogurt, water, or orange juice. You should swallow the entire mixture right away without chewing.

Before taking this medication, you should tell your healthcare provider of all medical conditions you or your child have, including:

  • Heart problems, heart defects, or high blood pressure
  • Personal or family history of psychosis, mania, bipolar disorder, depression, or suicide
  • Circulation problems in fingers and toes (Raynaud’s phenomenon)
  • Are pregnant, plan on becoming pregnant, or are breastfeeding

You should avoid Vyvanse if you have an allergy to other amphetamine products, lisdexamfetamine, or any of the inactive ingredients in its formulation. You should also not take this medication if you are being treated with linezolid or have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days.

Vyvanse side effects

The most common side effects of Vyvanse include:

  • Loss of appetite
  • Trouble sleeping
  • Dry mouth
  • Stomach pain
  • Headache
  • Nausea
  • Irritability
  • Constipation
  • Diarrhea
  • Increased heart rate

Vyvanse can sometimes cause serious adverse reactions such as:

  • Severe hypersensitivity reactions
  • Serious heart problems, including stroke, heart attack, and sudden death
  • Mental health problems such as hallucinations and mania
  • Decreased circulation in your fingers and toes
  • Serotonin syndrome, especially if taken with antidepressants such as SSRIs (fluoxetine and sertraline) or SNRIs (duloxetine and atomoxetine)

Speak with your prescribing doctor about the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Vyvanse. You should always seek medical advice for any questions or concerns relating to your medical condition or treatment. You can report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Vyvanse side effects and how to avoid them

How much does Vyvanse cost?

The estimated cost for a 1-month supply of brand name Vyvanse 30mg capsules without insurance is around $425. The generic version of Vyvanse is significantly cheaper, with savings of up to 80%.

Why is Vyvanse so expensive?

Brand-name drugs are always more expensive than generic drugs.  Vyvanse is so expensive because it is a brand-name medication. Fortunately for patients, there is a generic alternative available for sale that is significantly cheaper.

RELATED: Why is Vyvanse so expensive?

What foods to avoid with Xarelto

Xarelto is an anticoagulant medication used to treat and reduce your risk of blood clots. It was initially approved by the FDA in 2011 and is manufactured by Janssen Pharmaceuticals, Inc. It is important to avoid foods such as grapefruit and other medications such as blood thinners that can increase your risk of bleeding while taking this medication.

Learn more about what foods you should avoid with Xarelto and which foods are beneficial to eat while using this medication.

What is Xarelto?

Xarelto is the brand name of the active ingredient rivaroxaban. It is a factor Xa inhibitor that is FDA-approved to:

  • Reduce your risk of stroke and blood clots if you have atrial fibrillation (Afib)
  • Treat deep vein thrombosis (DVT)
  • Treat pulmonary embolism (PE)
  • Reduce your risk of another DVT
  • Prevent DVT if you are undergoing knee or hip replacement surgery
  • Prevent venous thromboembolism (VTE)
  • Treat VTE and reduce the risk of recurrent VTE in pediatric patients from birth to less than 18 years
  • Prevent blood clots in pediatric patients 2 years and older with congenital heart disease after a type of open-heart surgery called the Fontan procedure

With Xarelto, you are not required to take regular blood tests, whereas other blood thinners such as warfarin may require frequent blood tests. A prothrombin time (PT) and international normalized ratio (INR) are performed regularly when a person is taking warfarin to make sure the clotting time is normal and the dose does not need to be adjusted.

How does Xarelto work?

Xarelto is an anticoagulant medication that works by blocking a protein involved in the blood clotting process called factor Xa. When this protein is blocked, blood clots are less likely to form in your body which reduces your risk of having a stroke or heart attack.

Xarelto is typically taken once or twice daily, depending on the condition being treated. You can take Xarelto with or without food. You should not stop taking this medicine unless instructed by your healthcare professional. Stopping this medication suddenly can increase your risk of heart-related problems such as heart attack or stroke.

What are the side effects of Xarelto?

The most common side effects of Xarelto include:

  • Bleeding
  • Bruising
  • Back pain
  • Stomach pain
  • Dizziness
  • Fatigue

Xarelto can sometimes cause more serious side effects such as:

  • Increased risk of heart attack or stroke if Xarelto is discontinued too soon
  • Serious allergic reactions
  • Serious, life-threatening bleeding
  • Bleeding around the spine which can leave you paralyzed, especially before spinal surgery, spinal taps, or epidurals

These are not all of the possible side effects of Xarelto. You should seek medical advice from your healthcare professional for any questions or concerns relating to your medical condition or treatment.

What foods should I avoid with Xarelto?

You should avoid eating grapefruit or drinking grapefruit juice while taking this medication. It may increase the concentration of Xarelto in your bloodstream and lead to a major bleed.

Xarelto is not known to have a food interaction with leafy green vegetables. Leafy green vegetables can contain high levels of vitamin K that affect other blood-thinning medications such as Coumadin/Jantoven (warfarin). The manufacturer of Xarelto claims you can enjoy a full variety of healthy food without any dietary restrictions.

What foods are good to eat while taking Xarelto?

There is no specific diet you have to be on while taking Xarelto, but eating a healthy and balanced diet is always important. You should try and eat a diet consisting of:

  • fresh fruits and vegetables
  • whole grains
  • lean protein
  • low-fat dairy

Having a healthy diet can help improve your overall health. It can lead to a decrease in your weight, blood pressure, and cholesterol. This can help reduce your risk of developing cardiovascular disease, stroke, and other serious medical conditions. If you have any questions about what to eat while taking Xarelto, talk to your doctor or dietitian. They can help create a diet plan that is right for you.

Can you eat leafy green vegetables while taking Xarelto?

Xarelto is not known to have a food interaction with leafy green vegetables. Leafy green vegetables can contain high levels of vitamin K that affect other blood-thinning medications such as Coumadin/Jantoven (warfarin). The manufacturer of Xarelto claims you can enjoy a full variety of healthy food without any dietary restrictions.

Do carrots affect blood thinners?

Carrots are low in vitamin K and unlikely to affect your INR levels. Carrots should be safe to eat while on blood thinners.

Can you drink orange juice while taking Xarelto?

If you are taking Xarelto, you should avoid eating grapefruit or drinking grapefruit juice. There are several fruits that have no vitamin K that should be safe to drink while on Xarelto. This includes citrus fruits and juices, including tangerines, oranges, and clementines.

Can you eat bananas on blood thinners?

There is no known food interaction between bananas and blood thinners. You should be able to eat bananas without having to adjust your dose of any blood thinner you are taking.

Do eggs affect blood thinners?

There are certain foods that are considered safe to eat while on blood thinners which include eggs. They should have no effect on your clotting time.

Who can take Xarelto?

Xarelto is an anticoagulant medication that is used to prevent blood clots in people with an irregular heartbeat (atrial fibrillation) who are at risk of developing a blood clot. It is also used in the treatment of deep vein thrombosis and pulmonary embolism.

Before taking this medication, make sure your doctor is aware of your medical conditions, especially if you have any of the following:

  • An active bleed or history of bleeding disorders
  • Liver or kidney disease
  • Antiphospholipid syndrome (APS)
  • Are pregnant, plan on becoming pregnant, or are breastfeeding
  • Have a known allergy to rivaroxaban or any inactive ingredients in Xarelto

What are some drug interactions with Xarelto?

When Xarelto is taken with other medications, it can change how they work or increase the frequency and severity of side effects. You should ask your healthcare professional if any of the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take may interact with this medication, including:

  • Anticoagulants such as Coumadin (warfarin), Eliquis (apixaban), Pradaxa (dabigatran), Plavix (clopidogrel), Savaysa (edoxaban) and heparin
  • Non-steroidal anti-inflammatory drugs (NSAIDs) such as Motrin (ibuprofen), Aleve (naproxen), and aspirin
  • Drugs that are metabolized by the liver such as Tegretol (carbamazepine), Nizoral (ketoconazole), St. John’s wort, and Norvir (ritonavir)

Can you drink alcohol while taking Xarelto?

It is not known whether alcohol interacts with Xarelto. Xarelto does thin your blood and large amounts of alcohol may cause you to bleed more. You should ask your doctor if it is safe for you to drink alcohol while taking Xarelto.

How long does it take Xarelto to start working?

Xarelto typically takes between 2 to 4 hours for it to reach its full effects and will leave your bloodstream in about 24 hours.

What if I miss a dose of Xarelto?

Xarelto is typically taken once or twice a day, at the same time each day. You can take this medication with or without food.

If you take this medication twice a day and miss a dose, take it immediately after you remember it on the same day. You can take 2 doses of Xarelto at the same time to make up for a missed dose. You will then take the next dose at its regular time.

If you take this medication once a day and miss a dose, take it immediately after you remember it on the same day. You will then take the next dose at its regular time.

Does Lantus need to be refrigerated?

Lantus is a brand-name type of insulin that needs to be stored in the refrigerator between 36°F to 46°F (2°C to 8°C) before its first use. Lantus is available as a vial, and a prefilled insulin pen that is manufactured by Sanofi-Aventis U.S. Learn more about the storage conditions for Lantus and how to store it before and after you start using this medication.

What is Lantus (insulin glargine)?

Lantus is a long-acting insulin that is FDA-approved, along with diet and exercise to improve blood glucose levels in adults with type 2 diabetes and adult and pediatric patients (6 years and older) with type 1 diabetes. Lantus is not approved for the treatment of diabetic ketoacidosis.

Lantus is used as a basal insulin when your body does not make enough natural insulin. It also helps reduce the need for short-acting insulins to keep your blood sugars within normal range. Natural or endogenous insulin promotes the storage and inhibits the breakdown of glucose, fat, and proteins. Insulin controls high blood sugar by increasing the uptake of glucose into your muscle and tissues. It also prevents your liver from producing more sugar.

You should talk to your healthcare professional for medical advice about the possible risks and benefits of Lantus before starting treatment.

Does Lantus need to be refrigerated?

Lantus refrigeration before and after first use

Before the first use of Lantus: Store your unopened Lantus vial and Lantus SoloStar pen in the refrigerator between 36°F to 46°F (2°C to 8°C) away from heat and light. Do not freeze Lantus. Store your SoloStar pen with the pen cap on when it is not in use. Unopened insulin vials and pens can be used until the expiration date on the carton if they have been properly stored in the refrigerator. Unopened vials and pens should be discarded after 28 days if they have been stored at room temperature.

After the first use of Lantus: After you have used Lantus for the first time, you can store the open vials in a refrigerator from 36°F to 46°F (2°C to 8°C) or at room temperature below 86°F (30°C) for up to 28 days. You should store your SoloStar pen at room temperature below 86°F (30°C). Do not put your SoloStar pen back in the refrigerator. Discard your Lantus vial or Solostar pen 28 days after its first use, even if it has insulin left in it.

Can Lantus stay out of the fridge?

After its first use, Lantus vials can be stored in a refrigerator from 36°F to 46°F (2°C to 8°C) or at room temperature below 86°F (30°C) for up to 28 days.

Lantus SoloStar pens should not be put back in the refrigerator and should be kept at room temperature below 86°F (30°C) after their first use. They can be kept at room temperature for up to 28 days.

Do not store your Lantus vial or SoloStar pen in your car. Similar to other antidiabetic medications like Levemir (insulin detemir), Toujeo SoloStar (insulin glargine), Basaglar (insulin glargine), and Apidra (insulin glulisine), Lantus is very sensitive to low and high temperatures.

Can Lantus be frozen?

You should not freeze your Lantus vial and Lantus SoloStar pen or store them directly next to the cooling element in your refrigerator. You should immediately discard your vial or SoloStar pen if it becomes frozen. Do not thaw it out and reuse it.

How do you dispose of your Lantus pen needle or syringe?

You should place your used pen needles and syringes in an FDA-approved sharps disposal container immediately after use. Do not dispose of your pen needles and syringes in your household trash. If you don’t have an FDA-approved sharps container, you can use a container that is made of heavy-duty plastic and can be closed tightly with a puncture-resistant lid. It should also be leak resistant and labeled properly to warn others that there is hazardous waste inside the container. When your sharps container is full, follow your local guidelines for the proper way to dispose of it.

For more specific information about safe sharps disposal in the state that you live in, go to: http://www.fda.gov/safesharpsdisposal.

What are the side effects of Lantus?

Some common side effects of Lantus include:

  • Common cold symptoms
  • Low blood sugar
  • Infection
  • Headache
  • Swelling (edema)
  • Injection site reactions
  • Weight gain
  • Rash
  • Itching

Rare but serious side effects of Lantus can include:

  • Serious allergic reactions (hives, swelling of the tongue or throat, shortness of breath, or trouble breathing)
  • Low potassium levels (hypokalemia)
  • Heart failure if used along with TZDs (thiazolidinediones)
  • Severely low blood sugar (hypoglycemia)

You should talk to your healthcare provider about the potential side effects of Lantus before starting treatment.

When should you not use Lantus?

Do not use Lantus if you have a known hypersensitivity reaction to insulin glargine or any inactive ingredients in this product. You should also not use Lantus if you currently have low blood sugar levels. You should let your doctor know if you are pregnant, plan on becoming pregnant, are breastfeeding, or if you have medical conditions such as hypokalemia (low potassium levels) or heart failure.

What are some drug interactions with Lantus?

Make sure your healthcare provider is aware of all the prescription medications, over-the-counter drugs, vitamins, and supplements as they may interact. Some interactions with Lantus include:

  • Antidiabetic medications, including short-acting insulins such as Novolin R (regular insulin), Humalog (insulin lispro), or Novolog (insulin apart)
  • Antiadrenergic medications such as beta-blockers and clonidine

What dosage forms and strengths of Lantus are available?

Lantus is available in a strength of 100 units/ml in a 10ml multi-dose vial or a 3ml single-patient-use SoloStar prefilled pen

What do I do if I miss a dose of Lantus?

It is important for you not to miss a dose of Lantus. Your doctor or diabetic care team should develop a plan for missed doses with you. If you do miss a dose, follow their plan. Do not take extra doses of Lantus to make up for a missed dose.

How do I take Lantus?

  • Use Lantus exactly how your doctor prescribes it to you. Do not change your dose or stop taking this medication without discussing it with them first.
  • Check your insulin dose and label each time you give an injection to reduce the risk of medication errors.
  • Do not reuse needles or syringes as it can increase your risk of not getting the correct dose of Lantus. Using new needles and syringes with each injection also reduces your risk of infection.
  • You can take this medication at any time of the day but it should be taken at the same time each day.
  • Do not use Lantus if the solution is cloudy or has any color to it.
  • You can inject Lantus under the skin of your thighs, upper arms, or stomach. Rotate your injection site with each dose to reduce the risk of skin reactions. Do not inject this medication into thickened skin or skin that has pits or lumps. You should also avoid skin that is damaged, scarred, tender, bruised, or scaly.
  • Lantus should not be used in an insulin pump or injected into your vein (intravenously).

Top 10 migraine foods to avoid

Migraines are not just bad headaches. They are headaches that can cause severe pulsing or throbbing pain that can last for days; with pain so severe, it affects your ability to perform normal daily activities. Migraines are one of the most common neurologic disorders worldwide, affecting an estimated 12% of the population. The American Migraine Foundation estimates that at least 39 million Americans are migraine sufferers, but because many go undiagnosed, the actual number may be higher. In the United States, women are around three times more likely than men to have migraines. Each year, almost 17% of women get migraine attacks compared to 6% of men.

Here we will look at what a migraine is, its symptoms, and what specific foods may trigger a migraine attack. We will also look at what foods you should eat and the treatments available to help treat symptoms and improve your quality of life.

What is a migraine?

A migraine is a common neurological disorder that can cause symptoms such as a throbbing, pulsing headache on one side of your head, as well as nausea, vomiting, and sensitivity to light. Your headache pain is typically due to the dilation of blood vessels in your brain. A migraine headache can worsen with lights, sounds, odors, and physical activity and can last from hours to several days.

There are several types of migraines, including:

  • Migraine with aura: Around 1 in 3 people with a migraine experience an aura. This warning sign (aura) is usually one that affects your sight, such as having a blind spot or seeing flashing lights.
  • Migraine without aura: This type is often called a common migraine or an episodic migraine. It is the most common type of migraine. It comes without warning and can last up to a few days.
  • Chronic migraine: A chronic migraine affects around 2 out of 100 people with episodic migraines. It is defined as having a migraine at least 15 days per month for at least three months. The symptoms are similar to those of a common migraine but may vary in intensity.
  • Silent migraine: This type will include the aura symptom without the head pain that typically follows it.
  • Hemiplegic migraine: You will typically experience a temporary weakness or paralysis on one side of your body as part of this rare type of migraine. You may or may not experience head pain with hemiplegic migraine.
  • Menstrual migraine: Hormonal changes that occur throughout a woman’s life are known to be a potential trigger for women who have migraines. Over 50% of women that suffer from migraines report that menstruation is a trigger for a migraine.
  • Migraine with brainstem aura: This type of migraine used to be called a basilar-type migraine. It is a rare type of migraine that includes neurological symptoms such as slurred speech, dizziness, and double vision, along with common migraine symptoms.
  • Ocular or retinal migraine: This rare type of migraine has symptoms that include visual changes such as seeing colors or flashing lights. It also usually involves the partial or total loss of vision in one eye. The loss of vision will typically last less than an hour and be followed by a migraine headache.
  • Status migrainosus: With this type of migraine, you will have head pain that lasts longer than 3 days. It can be caused by medications or medication withdrawal.
  • Abdominal migraine: While this type of migraine can occur in adults, it is more commonly seen in children. With an abdominal migraine, you will have symptoms such as stomach pain, nausea, and vomiting but will not have head pain. Children will typically stop getting abdominal migraines but will often develop migraine headaches as they get older.

What are some symptoms of a migraine?

Migraines, which can affect people of all ages, can progress through four phases: prodrome, aura, headache, and post-drome. You can have various symptoms based on which of the 4 phases that occur. Not everyone who suffers from migraines will go through all 4 phases.

Prodrome

This stage occurs 1 to 2 days before your migraine and can provide you with a warning that a migraine could be coming. It includes symptoms such as:

  • Irritability
  • Mood changes
  • Food cravings
  • Fatigue and frequent yawning
  • Nausea
  • Insomnia
  • Neck pain or muscle stiffness
  • Increased urination

Aura

A migraine aura typically occurs within an hour before your headache starts and can last up to 60 minutes. Symptoms include:

  • Visual disturbances such as seeing bright spots or flashing lights
  • Temporary vision loss
  • Numbness or tingling sensations
  • Speech changes or difficulty speaking
  • Ringing in your ears

Headache

A migraine headache can last up to 72 hours if not successfully treated. During this phase, you may experience:

  • Throbbing or pulsating pain, usually on one side of your head
  • Sensitivity to light, noise, and odors
  • Nausea
  • Vomiting
  • Stomach pain
  • Loss of appetite
  • Sweating or cold chills
  • Dizziness

Postdrome

Following a migraine attack, you may have symptoms such as:

  • Fatigue
  • Unable to concentrate
  • Confusion
  • Feel depressed
  • Euphoric mood

What are some medications used for migraines?

Several types of medications help reduce migraine symptoms. Some are used for migraine treatment, and some are used for migraine prevention. These can include:

  • Non-steroidal anti-inflammatory drugs (NSAIDs) such as Motrin (ibuprofen)
  • Ergot alkaloids such as Migranal (dihydroergotamine)
  • Triptans such as Imitrex (sumatriptan)
  • CGRP antagonists such as:
    • Nurtec ODT (rimegepant), which is used for the acute treatment of migraine attacks, with or without aura, in adults. It is also used as a preventive treatment for episodic migraines.
    • Ajovy (fremanezumab), which is used for the preventive treatment of episodic or chronic migraine in adults.
    • Emgality (galcanezumab), which is given to adults to prevent migraines and to treat episodic cluster headaches.
  • Tricyclic antidepressants such as Elavil (amitriptyline)
  • Serotonin and norepinephrine reuptake inhibitors (SNRIs) such as Cymbalta (duloxetine)
  • Beta-blockers such as Tenormin (atenolol)
  • Botox (botulinum toxin type A)

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What foods should I avoid with a migraine?

Several factors may trigger migraine attacks, including dehydration, stress, hormonal changes, certain foods, and lack of sleep. Few dietary triggers are scientifically proven but are usually self-reported by people with migraines. Some common food triggers that have been reported include:

  • Cured, fermented, or processed meats that contain nitrates and nitrites, such as hot dogs, bacon, ham, and fish.
  • Food additives and artificial sweeteners such as aspartame (diet sodas and sugar-free foods), monosodium glutamate (MSG, found in soy sauce and packaged foods such as canned soup), or preservatives.
  • Pickled foods such as pickles, olives, and sauerkraut.
  • Dairy products like aged cheese which includes blue cheese, brie, cheddar, feta, mozzarella, muenster, parmesan, and swiss that contain tyramine. Yogurt, sour cream, and buttermilk may also trigger headaches.
  • Certain alcoholic beverages, such as red wine, which contain sulfites. Other beverages include beer, Scotch, and whiskey. Alcohol is thought to be the most common trigger for migraines.
  • Products that contain caffeine, such as coffee, tea, energy drinks, and supplements.
  • Fresh fruits and juices such as citrus fruits, bananas, avocados, red plums, raspberries, papayas, and passion fruit.
  • Dried fruits such as figs, dates, and raisins.
  • Chocolate, which is considered the second most common trigger of migraines.
  • The majority of beans, which include lima, fava, navy, pinto, garbanzo, lentils, and peas.
  • Certain vegetables, such as onions, tomatoes, and garlic.

What foods are good to eat while having a migraine?

There are certain foods that may help with current migraine symptoms or prevent future migraines. You should seek medical advice from your healthcare provider to see if these changes in your diet might help, including:

  • Magnesium-rich foods, including tuna or dark leafy green vegetables such as spinach, kale, collards, or mustard greens.
  • Food that is rich in omega-3 fatty acids, which include salmon, mackerel, flax seeds, and almonds.
  • Increase how much water you drink, as dehydration is a trigger for migraines.
  • A study from 2014 found that powdered ginger was as effective in relieving head pain during a migraine attack as Imitrex (sumatriptan).
  • Eating smaller meals throughout the day may help avoid low blood sugar (hypoglycemia), which is a potential migraine trigger.
  • Dark chocolate and caffeine may help with your migraine, but they can also be a trigger for some people.

Although no dietary changes will completely prevent migraines, a well-balanced, healthy diet may help you manage symptoms and reduce your risk of triggering a migraine.

What is the best milk for migraine sufferers?

Almonds and cashews are high in magnesium, a mineral that the American Migraine Foundation says may help protect against migraines. It is thought that magnesium may help block the signals that produce migraine auras. It may also block the chemicals that transmit pain signals to your brain. Drinking almond or cashew milk can increase your magnesium levels and help reduce your incidence of migraine attacks.

Does Trulicity need to be refrigerated?

Trulicity is a brand-name prescription drug used to treat type 2 diabetes. It should be stored in the fridge between 36°F – 46°F (2°C – 8°C) before using the medication for the first time and can be stored at room temperature for up to 14 days. Trulicity is sensitive to high and low temperatures. Learn more about the storage conditions for Trulicity and how to store Trulicity before and after you start using it.

What is Trulicity (dulaglutide)?

Trulicity (dulaglutide) is a prescription drug used to treat type 2 diabetes, manufactured by Eli Lilly and Company. It is an FDA-approved non-insulin treatment for high blood glucose levels that comes in a single-dose pen or a prefilled syringe and is administered by injection.

It may also be given to reduce the risk of major adverse cardiovascular events (such as a stroke or heart attack) occurring in adults with type 2 diabetes who may be at a high risk of cardiovascular disease. or who already have cardiovascular disease.

Trulicity is a safe and effective diabetes medication when it is taken as directed by your healthcare provider. When Trulicity is taken weekly as directed by your healthcare provider, along with exercise and diet, this medication may help lower blood sugar levels in adults with type 2 diabetes.

The active ingredient in Trulicity is dulaglutide. Dulaglutide is in the drug class known as glucagon-like peptide-1 (GLP-1 receptor agonist). GLP-1 is a hormone released from the gut in response to food and helps to regulate glucose metabolism by stimulating insulin release from the pancreas and slowing gastric emptying.

Talk to your healthcare provider about the potential risks and benefits of Trulicity before starting treatment.

How does Trulicity work?

Trulicity works to help manage blood sugar levels in adults with type 2 diabetes. The medication also helps lower the risks of heart problems in people with heart disease and diabetes. Trulicity attaches to certain receptors on the cells of your pancreas, which tells the pancreas to release insulin when the body’s blood sugar level is high. Trulicity helps your pancreas release more insulin by attaching to the cells and lowers your blood sugar.

Trulicity also increases the time it takes for food to move through your stomach and keeps your blood sugar level from spiking after eating.

This medication will also block glucagon and lower your blood sugar. Glucagon is a hormone that tells your liver to break down sugar and release it into your blood.

Trulicity (Dulaglutide) vs Victoza (Liraglutide)

The AWARD-6 study compared once-weekly Trulicity with once-daily Victoza (Liraglutide) used by people with type 2 diabetes. The study suggests that both drugs are similar in terms of Hb A1c reduction, and people taking Victoza experienced slightly more weight loss. Nausea side effect rates were experienced similarly with both drugs.

Trulicity storage requirements

Trulicity storage conditions

BEFORE FIRST USE: Trulicity should be stored in the refrigerator (between 36°F to 46°F or 2°C to 8°C) until the first time you use it.

AFTER FIRST USE: After you have used Trulicity pen or Trulicity prefilled syringe for the first time, it can remain stored in the refrigerator or kept at room temperature (between 59°F to 86°F or 15°C to 30°C) for up to 14 days. This allowable 14-day room temperature exposure may be one single 14-day exposure, or it can be broken up into multiple exposures. There is no limit to the number of room temperature exposures as long as the total time does not exceed 14 days (336 hours).

It is important to note that Trulicity is sensitive to extreme temperatures. If the prefilled syringe or pen is exposed to temperatures higher than 86°F (30°C), it can go bad and no longer be safe.

Do not freeze Trulicity. Trulicity can become damaged if it is exposed to extreme temperatures. It should not be stored in a place that is too hot or too cold. Avoid storing Trulicity in the bathroom or near a sink, as it may be exposed to moisture.

It is important to follow the storage instructions provided by your healthcare provider or pharmacist. Do not use Trulicity if it has been left at room temperature for more than 14 days, frozen, or the expiration date has passed. You will need to use a new pen or prefilled syringe. If you have any questions about how to store Trulicity, you should contact your healthcare provider or pharmacist.

How long can Trulicity be refrigerated?

Trulicity can be stored in the refrigerator between 36°F – 46°F (2°C – 8°C) until its expiration date.

Can Trulicity stay out of the fridge?

After first use, Trulicity can be stored out of the fridge at room temperature (between 59°F – 86°F or 15°C – 30°C) for up to 14 days.

If Trulicity has been stored at room temperature for more than 14 days, it should be discarded.

Do not store your Trulicity pens or prefilled syringes in the car. Always keep Trulicity away from the light and away from heat. Similar to other diabetes medications like VictozaOzempic, and many other injectable drugs, Trulicity is sensitive to high and low temperatures.

What if I left Trulicity out of the fridge overnight or forgot to put Trulicity in the fridge?

If you left Trulicity out of the fridge overnight at room temperature, it could be returned to the fridge and used as usual. Trulicity can be left at room temperature for up to 14 days, so as long as you return it to the fridge in less than 14 days, you will be able to continue using it as long as the total time stored at room temperature does not exceed 14 days (336 hours).

What happens to Trulicity if it is not refrigerated?

According to the manufacturer, it is not recommended to use Trulicity if it is stored at room temperature for longer than 14 days (336 hours).

Can Trulicity be frozen?

Do not freeze Trulicity or store the pens or prefilled syringes directly next to the cooling element in your refrigerator. Do not take Trulicity if it is frozen.

Once frozen, the solution in Trulicity will break down and not regain its original efficacy. Trulicity is not safe for use after being frozen. Even if the solution has thawed, you should throw it away and get a new prefilled syringe or pen.

Does Trulicity expire?

Trulicity expires on the expiration (EXP) date printed on the label or carton. As well, it cannot be used after 14 days when stored at room temperature.

How do I travel with Trulicity?

If you need to take Trulicity with you when you are away from home, you can store it at room temperature for up to 14 days. However, it is important to protect the medication from light and heat during this time. If the Trulicity has been stored at room temperature for more than 14 days, it should be discarded.

How do I keep my Trulicity cold while traveling?

Store Trulicity at 36°F – 46°F or 2 – 8°C when transporting or traveling, where possible. The pen may be kept at room temperature (below 86°F or 30°C) for up to a total of 14 days. When traveling by air, place the pen in the carry-on baggage.

The manufacturer, Eli Lilly and Company, does not test, market, or sell coolers to keep Trulicity cold for long periods of time and does not recommend any of them. If a travel storage cooler is used, it is important to remember that Trulicity should not touch ice or frozen gel packs.

How to dispose of the Trulicity pen and prefilled syringe?

Put your Trulicity injection pen and needle in an FDA-cleared sharps container right away after use. Your Trulicity pen and needle should not be thrown away in the household trash.

A household container can be used if you don’t have a specific FDA-cleared sharps container. If you are using your own container, it should be created from heavy-duty plastic and can be securely closed in a stable upright, and leak-proof container. The lid should be tight and puncture-resistant, whereby sharps are not able to come back out. It should be labeled properly to warn people of hazardous materials inside the container.

When your container for sharps disposal is nearly full, you should follow the disposal guidelines in your community. There are no special instructions for disposing of the Trulicity pen or prefilled syringe.

What are the side effects of Trulicity?

The most common side effects of Trulicity are:

  • Nausea
  • Diarrhea
  • Vomiting
  • Stomach (abdominal) pain
  • Decreased appetite
  • Indigestion
  • Fatigue

Rare but serious side effects of Trulicity can include:

  • Low blood glucose (hypoglycemia)
  • Inflammation of your pancreas (pancreatitis)
  • Kidney injury
  • Serious allergic reactions
  • Severe stomach problems
  • Changes in vision
  • Gallbladder problems

You should talk to your doctor about the potential side effects of Trulicity before starting treatment.

When should you not use Trulicity?

Do not use Trulicity If:

  • You have Type 1 Diabetes
  • You or anyone in your family ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC)
  • You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • You are allergic to dulaglutide or other ingredients in Trulicity

Tell your physician about all of your medical conditions, including if you currently have or previously have had:

  • Kidney problems
  • Gallbladder problems
  • Pancreatitis
  • Liver problems
  • A history of alcoholism
  • Low blood sugar (hypoglycemia)
  • Any other medical conditions

Speak with your healthcare provider if:

  • You have other medical conditions, including problems with your pancreas, liver, kidneys, or stomach, or you have a history of diabetic retinopathy
  • You are taking any other diabetes medications, such as insulin or sulfonylureas
  • You are currently pregnant, or you are planning to become pregnant, or you are breastfeeding or  are planning to breastfeed
  • You are taking any other prescription drugs or over-the-counter medications, herbs or vitamins

What doses of Trulicity are available?

Trulicity is available as a pen and prefilled syringe in the doses 0.75 mg, 1.5 mg, 3 mg and 4.5 mg.

The recommended starting dose of Trulicity is a weekly dose of 0.75 mg injected subcutaneously, Increased to 1.5 mg once weekly for additional glycemic control.

If additional glycemic control is needed, the dose is increased in 1.5 mg increments after at least 4 weeks of taking the current dosage.

Your healthcare provider may want you to use one or more medications in addition to Trulicity, such as sulfonylurea, metformin, thiazolidinedione or insulin.

What do I do if I miss a dose?

If you have missed a dose of your Trulicity, inject the missed dose once you remember. If it is nearly time for your next dose, skip the dose you missed and inject the next dose at your regular time. Do not inject a dose that is double the amount of Trulicity to make up for a dose that was missed.

How to use Trulicity

Your healthcare provider can help you choose the best injection site for your body. It is recommended to use different spots in the injection site area every time you inject Trulicity. Suggested injection site areas are your upper arm, abdomen, or thigh.

What is the best time of day to inject Trulicity?

Trulicity is taken once weekly. On the day of the week that you usually take Trulicity, you can take your weekly dose at any time of the day, with or without food.

Should Trulicity be injected cold?

You can inject Trulicity cold, but it is more likely to sting if injected cold. you can allow Trulicity to warm up to room temperature for at least 30 minutes before injecting it, which will be more pleasant than injecting it cold.

Foods to avoid with Trulicity

It is recommended to avoid foods and drinks that are high-fat, sugary, and calorie-dense.

You should also limit the amount of alcohol you drink, as it may cause hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) for those with diabetes.

RELATED: What foods to avoid with Trulicity

Linzess alternatives: which other medications can I take?

Linzess (linaclotide) is the brand name of a prescription medication manufactured by AbbVie and Ironwood Pharmaceuticals. It is used to treat constipation, but it is not a laxative. Most often, it’s prescribed to treat IBS-C (irritable bowel syndrome with constipation) and chronic idiopathic constipation (CIC).

Linzess is an expensive brand-name medication with several alternatives available. Learn more about what Linzess is, how it works, its side effects, and its alternatives.

What is Linzess?

Linzess belongs to a group of prescription drugs called guanylate cyclase-C agonists. The active ingredient in Linzess is called linaclotide. Linaclotide is not easily absorbed in your body which is a positive result as the drug is able to reach your bowels where it is able to do its work, instead of being absorbed and dispersed within your body.

When linaclotide reaches your bowels, it binds to the cells in the walls of your gut to stimulate bowel movements. Once there, it increases the amount of water and other fluids that pass from your body into your bowels, softening your stools. It does this by increasing the secretion of chloride and water. It also decreases the activity of sensory cells in your bowels, reducing any pain felt.

If someone is constipated, they find it difficult to pass a stool. Their stools may be hard and dry, and they may feel bloated and in pain. This can lead to the development of hemorrhoids, anal fissures, and fecal impaction. Chronic constipation is constipation that lasts several weeks or longer. Irritable bowel syndrome (IBS) is a group of conditions that can cause abdominal pain and bowel problems, including constipation. You should not use linaclotide if you have a blockage in your intestines.

RELATED: What is Linzess

What are the side effects of Linzess?

Linzess can cause adverse reactions. The most common side effects tend to be mild and restricted to the bowels, as the medication is not absorbed easily into your blood. From clinical trial data, typical side effects can include:

  • Gastrointestinal side effects such as diarrhea, bloating (abdominal distension), cramping, stomach pain, flatulence, dizziness
  • Infection side effects such as sinusitis and upper respiratory tract infection

Less common side effects of Linzess include:

  • Viral gastroenteritis
  • Allergic reactions e.g. hives
  • Severe diarrhea
  • Severe stomach pain
  • Weight loss or weight gain

Although diarrhea is a common adverse effect of Linzess, it should pass. If it lasts for more than seven days, and you feel lightheaded, dizzy, or faint (signs of dehydration), or if your diarrhea is severe, stop taking the medication and contact your physician. Diarrhea caused by Linzess can stop other medications from working properly, especially medicines with exact doses. If side effects persist, you may be offered an alternative drug such as Amitiza.

Prolonged diarrhea could stop birth control medication from working, so you should use other methods of contraception when taking Linzess. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

If you experience any serious side effects while taking this medication, you or your healthcare provider can send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-FDA-1088).

What doses of Linzess are available?

Linzess is available in capsule form in the following doses: 72 mcg, 145 mcg, and 290 mcg.

The recommended dosage in adults will depend on the condition being treated. Linzess is not recommended for pediatric patients younger than 18 years of age. You should take this medication on an empty stomach at least 30 minutes before your first meal of the day.

Do not chew or crush the capsule or the contents of the capsule. If you have problems swallowing capsules whole or have a nasogastric or gastrostomy tube, refer to the full prescribing information for how to open the capsule and how to take it with applesauce or water.

RELATED: Linzess Dosage

What happens if you stop taking Linzess?

Stopping treatment with Linzess may cause withdrawal symptoms, such as changes to bowel movements and the return of chronic constipation symptoms within one week.

Linzess drug interactions

Linzess can interact with other medications. These include:

  • Progestins – etonogestrel, levonorgestrel, norgestrel
  • NSAIDs – bromfenac, diclofenac, ibuprofen, naproxen
  • Proton pump inhibitors – esomeprazole, lansoprazole, omeprazole
  • Levothyroxine
  • Bisacodyl
  • Magnesium hydroxide

Linzess can interact with other medications. This can change how Linzess and other medications work and make side effects more likely. Tell your prescribing physician about all drugs you’re taking, including over-the-counter drugs, vitamins, and dietary supplements. In particular, tell them if you’re taking medicines that increase the risk of diarrhea, like laxatives, medicines for stomach ulcers, and NSAIDs.

Why is Linzess dangerous?

Linzess may cause severe diarrhea and lead to severe dehydration in a child (loss of a high amount of body salt and water). You should only take Linzess under the advice of a doctor. Do not take Linzess if you have a bowel blockage.

Why is Linzess so expensive?

Linzess is a brand-name medication currently not available in a generic form. Branded medications generally are more expensive, mostly due to the manufacturers who have researched, developed, and produced the drug re-couping their costs.

RELATED: Why is Linzess so expensive?

Are Amitiza and Linzess the same?

Amitiza and Linzess both treat constipation, but they are not the same. Amitiza is classed as a bicyclic fatty acid and prostaglandin E1 derivative and is taken twice a day. Linzess is classed as a guanylate cyclase C agonist and is taken once daily.

Linzess vs Amitiza

Amitiza is prescribed for chronic idiopathic constipation, opioid-induced constipation, and irritable bowel syndrome with constipation. It is available in a generic form and may cause diarrhea, headache, or nausea as side effects. Amitiza has only 1 drug interaction but more disease interactions than Linzess. You are advised to discuss which treatment is the most suitable for you with your healthcare provider.

Linzess vs Miralax

Miralax is prescribed for bowel preparation, acute constipation, and constipation. It is available in a lower-cost generic form. Miralax also has more side effects and drug interactions than Linzess.

What is a good alternative to Linzess?

FDA-approved alternatives to LInzess include:

  • Amitiza (lubiprostone), belongs to a drug class known as chloride channel activators. Amitiza is FDA-approved for the treatment of CIC in adults, opioid-induced constipation (OIC) in adults with chronic non-cancer pain, and IBS-C in women 18 years of age and older. Doses of Amitiza will depend on the condition you are being treated for. Common side effects of Amitiza include nausea, vomiting, diarrhea, gas, bloating, and indigestion. Those experiencing severe diarrhea, fainting, low blood pressure, or prolonged breathing problems should discontinue Amitiza and speak to their healthcare provider immediately. Amitiza is not recommended for use in people with GI obstruction
  • Lactulose, an osmotic laxative, is available in solution and powder form to be mixed with water before consumption. Lactulose is indicated for the treatment of chronic constipation. Common side effects of lactulose include nausea, vomiting, bloating, and gas. Speak to your doctor if you are intending to use lactulose if you are diabetic
  • Motegrity, a serotonin-4 (5-HT4) receptor agonist used for the treatment of CIC in adults. Side effects of Motegrity include abdominal pain, diarrhea, nausea, vomiting, bloating, gas, fatigue, headaches, and dizziness. Motegrity may also cause more serious side effects such as behavior and suicidal thoughts. Those experiencing this side effect should discontinue Motegrity and speak to their healthcare provider immediately. Motegrity is not recommended for use in people with intestinal obstruction or perforation
  • Trulance (plecanatide), is also a guanylate cyclase-C agonist. Trulance is similar to LInzess in terms of the side effects and allergic reactions it causes. Those experiencing severe diarrhea should speak to their healthcare provider immediately. Trulance is also used for the treatment of CIC or IBS-C in adults. It is not recommended for use in children under 18 years of age and is also contraindicated in children younger than 6 years old due to it causing severe dehydration. Trulance is also not recommended for use in patients with gastrointestinal (GI)obstruction
  • Zelnorm (tegaserod), is also a serotonin-4 (5-HT4) receptor agonist for the treatment of IBS-C in adult women under 65 years of age. Side effects of Zelnorm include diarrhea, nausea, indigestion, dizziness, headaches, and anemia
  • Stimulant laxatives such as Dulcolax (bisacodyl)
  • Saline laxatives such as magnesium
  • Bulk-forming laxatives such as psyllium
  • Stool softeners such as Colace. These draw water into the stool, making them softer and easier to pass

Is there a generic alternative to Linzess?

A generic version of Linzess is not currently available.

Is lactulose better than Linzess?

Lactulose is a cheaper alternative, with fewer side effects than Linzess. Lactulose is available as a liquid, powder for reconstitution, or as a syrup. Lactulose does have more drug interaction and disease interactions than Linzess. You are advised to speak to your doctor for medical advice about your medical condition before starting any new treatments for constipation.

Is there an over-the-counter drug similar to Linzess?

Over-the-counter drugs similar to Linzess include:

  • Stool softeners
  • Saline laxatives such as magnesium
  • Osmotic laxatives such as Miralax
  • Stimulant laxatives such as Dulcolax (bisacodyl)
  • Bulk-forming laxatives such as psyllium
  • Probiotics
  • Peppermint oil

Natural alternatives to Linzess

Lifestyle and dietary changes are natural remedies that may help relieve constipation and IBS symptoms and may be used with prescription drugs to aid your digestive system. Make sure you drink plenty of water and have fiber in your diet to help with the prevention of constipation. Exercise, for example, walking after a meal, can also help with bowel motility.

Speak to a registered dietitian or doctor of gastroenterology for medical advice about dietary changes that may help constipation.

What are some natural food sources of fiber?

Fiber is available in fruit sources such as apples, berries, and pears. Vegetables also contain fiber supplements, these include foods such as avocado, artichokes, nuts, wholegrain, and seeds.

What are the home remedies for IBS constipation?

Some remedies that help with constipation and improve your quality of life include exercise, reducing dairy intake, drinking plenty of water, relaxing, eating a healthy, well-balanced diet, and using laxatives carefully.

Trulicity alternatives: which other diabetes medications can I take?

Trulicity is the brand name for a prescription drug used in combination with diet and exercise to treat type 2 diabetes in adults. It is not indicated to treat patients with type 1 diabetes mellitus or diabetic ketoacidosis. Trulicity is a glucagon-like peptide 1 (GLP-1) receptor agonist that helps reduce your blood glucose levels. The active ingredient in Trulicity is dulaglutide which stimulates insulin secretion and reduces glucagon release, depending on your blood sugar level.

Trulicity is an expensive brand-name medication with several alternatives available. Learn more about what Trulicity is, how it works, its side effects, and its alternatives.

What is Trulicity?

Trulicity is a glucagon-like peptide 1 (GLP-1) receptor agonist. GLP-1 is a hormone that binds and activates GLP-1 receptors. Activating these receptors lowers blood sugar by stimulating insulin secretion and reducing glucagon release. These are done in a glucose-dependent manner, meaning if your blood sugar is high, your body will secrete more insulin and less glucagon. Trulicity can also delay the time it takes food to empty out of your stomach after eating. This helps reduce the rate glucose circulates in your bloodstream.

RELATED: What is Trulicity

What are the reasons for taking Trulicity?

Trulicity is a GLP-1 receptor agonist that is FDA-approved (Food and Drug Administration) to:

  • Improve blood glucose control when used along with exercise and diet in adults with type 2 diabetes
  • Reduce the risk of serious cardiovascular events (heart attack) in adults with type 2 diabetes mellitus who have known cardiovascular disease or multiple cardiovascular risk factors, including high cholesterol, high blood pressure, and smoking

Trulicity is not a weight loss drug, but those taking Trulicity may lose weight as a side effect and may be prescribed dulaglutide off-label for weight loss if they are suffering from obesity or are overweight.

Side effects of Trulicity

The most common side effects of Trulicity reported include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Decreased appetite
  • Weight loss

Some possible serious side effects of Trulicity include:

  • Increased risk of thyroid tumors
  • Pancreatitis
  • Diabetic retinopathy complications
  • Severe gastrointestinal reactions
  • Hypoglycemia when used along with insulin secretagogues or insulin
  • Acute kidney injury
  • Increased heart rate
  • Acute gallbladder disease
  • Hypersensitivity reactions

You can report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Does Trulicity cause nightmares?

Trulicity has been seen to cause nightmares as a side effect, especially for males, between the ages of 50 and 59 that have been taking Trulicity for less than 1 month. Trulicity was also seen to cause abnormal dreams, especially in females, over the age of 60 who had been taking Trulicity for between 1 to 6 months.

What are the most commonly prescribed doses of Trulicity?

  • 0.75 mg/0.5 ml single-dose pen
  • 1.5 mg/0.5 ml single-dose pen
  • 3 mg/0.5 ml single-dose pen
  • 4.5 mg/0.5 ml single-dose pen

RELATED: Trulicity Dosage

How to take Trulicity

  • Inject Trulicity under the skin of your stomach (abdomen),  upper arm, or thigh. Do not inject Trulicity into a muscle or vein
  • Use Trulicity once a week on the same day each week at any time of day. You could change the day you give the injection if your last dose was given at least 3 days before
  • If you miss a weekly dose of Trulicity, take the missed dose immediately if there are at least 3 days until your next scheduled dose. If there are less than 3 days until your next dose, wait and take the next dose on your regularly scheduled day
  • You can take Trulicity with or without food
  • Do not mix Trulicity and insulin in the same injection
  • You may give an injection of Trulicity and insulin in the same area of the body, but not right next to one another
  • Rotate your injection site with each weekly injection
  • Discuss with your doctor how to recognize and treat hypoglycemia (low blood sugar), and hyperglycemia (high blood sugar)
  • Store Trulicity in its original carton in the refrigerator at 36°F to 46°F away from light. You can keep each single-dose pen at room temperature for up to 14 days. Do not freeze Trulicity or use it if it’s been frozen

RELATED: Does Trulicity need to be refrigerated?

Trulicity contraindications

Trulicity is contraindicated in patients with:

  • A personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Serious allergic reaction to dulaglutide or any of the product components

Trulicity warnings

  • Trulicity may cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC)
  • Inflammation of the pancreas (pancreatitis) has been reported in clinical studies. Discontinue Trulicity immediately if pancreatitis is suspected and do not restart it if pancreatitis is confirmed
  • Increased risk of diabetic retinopathy complications. If you have a history of diabetic retinopathy, you should be monitored for the progression of this condition
  • Your risk of hypoglycemia is increased if Trulicity is used along with an insulin secretagogue (sulfonylurea) or insulin. A lower dose of the secretagogue or insulin may be necessary
  • Increased risk of acute kidney injury. Your renal function should be monitored if you have renal impairment and severe adverse gastrointestinal reactions
  • Serious hypersensitivity reactions (anaphylaxis, angioedema) have been reported with Trulicity. If this reaction occurs, discontinue using Trulicity immediately and seek medical advice
  • Increased risk of acute gallbladder disease
  • Trulicity use may be associated with severe gastrointestinal adverse reactions. Trulicity is not recommended in patients with severe gastrointestinal disease
  • Tell your doctor if you are pregnant or breastfeeding. Trulicity should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known if this medication is present in breast milk

Trulicity drug interactions

When Trulicity is taken with other medications, they may interact and change how those medications work. They may also make some side effects more likely and severe. Make sure your doctor is aware of all prescription and over-the-counter medications, including supplements you are taking. Some common drug interactions of Trulicity include:

  • Increased risk of hypoglycemia if Trulicity is used in combination with insulin secretagogues (sulfonylureas) or insulin
  • Trulicity may delay gastric emptying so it can impact the absorption of oral medications taken along with it. Trulicity should be used with caution in patients with gastroparesis

What are the benefits of using Trulicity?

Trulicity is a once-weekly easy-to-use injectable medicine for the treatment of adults with type 2 diabetes to help improve blood sugar control to reduce the risk of cardiovascular problems such as heart attack, stroke, or death in people with heart disease or other cardiovascular risk factors. Trulicity has the added benefit of causing weight loss, which is especially beneficial in patients with obesity.

Trulicity alternatives

There are many other alternative types of diabetes medications your healthcare provider may prescribe if Trulicity is not for you. These will vary in the side effects they cause and how much they cost. FDA-approved alternatives include:

What medication is the same as Trulicity?

While there are no medications that are exactly the same as Trulicity, there are several other medications that are in the same class of drugs known as GLP-1 agonists, including Ozempic, Victoza, Byetta, and Rybelsus.

Is there a cheaper alternative to Trulicity?

There are many alternative treatments for diabetes. However, which treatment is best for you will need to be discussed with your doctor. Metformin is the preferred drug of the first choice in most cases of diabetes. It also just so happens to be an inexpensive alternative to Trulicty.

Is there a generic alternative for Trulicity?

Currently, a generic version of Trulicity is not available, with the earliest date a generic version may become available from 2027 to 2029 when the patent for Trulicity expires.

Foods to avoid with Trulicity

While there are no foods known to interact with Trulicity, which needs to be avoided, some foods may make the side effects of Trulicity worse. If you experience any bothersome side effects after eating, try avoiding that food to see if your symptoms improve.

In general, it is recommended to eat a healthy diet when taking Trulicity or any other medication for diabetes. A healthy diet includes foods from all food groups and limits foods high in sugar, fat, and calories. Speak to your healthcare provider about what types of foods are best for you.

It is recommended to avoid foods and drinks that are high-fat, sugary, and calorie-dense, for example, alcohol, fast food, processed food, soda, cake, cookies, pastries, chips, and healthy snacks such as granola bars that are actually high in sugar.

RELATED: What foods to avoid with Trulicity

Ozempic vs Trulicity

Trulicity (semaglutide) and Ozempic (semaglutide) both belong to the same drug class, glucagon-like peptide-1 (GLP-1) agonists. They are both given as a weekly subcutaneous injection under the skin. Trulicity and Ozempic are both indicated to help improve blood glucose control in adults with type 2 diabetes and lower the risk of cardiovascular events in those with type 2 diabetes and heart disease. They both cause similar side effects as well.

The active ingredients they contain are the most important difference between Ozempic and Trulicity. Ozempic contains a GLP-1 receptor agonist called semaglutide, whilst Trulicity contains a GLP-1 receptor agonist called dulaglutide. Semaglutide and dulaglutide do work in similar ways, but they are not identical, and you may respond to them differently.

The doses prescribed for each drug also vary. Ozempic pens can be prescribed in 0.25 mg, 0.5 mg, and 1 mg doses, whereas Trulicity pens can be prescribed in larger 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg doses. Ozempic is typically taken in smaller doses, as independent research has shown it to be more effective than Trulicity.

RELATED: Ozempic vs Trulicity

Which one is better Trulicity or Ozempic?

Both Ozempic and Trulicity are proven and effective treatments for type 2 diabetes. However, in the SUSTAIN 7 clinical trial that compared the two medications, Ozempic was found to be more effective than Trulicity. The study was conducted on 1,201 patients with type 2 diabetes from 194 hospitals in 16 countries. Over the 40-week trial, Ozempic lowered blood glucose levels further than Trulicity on average and caused more weight loss. No noteworthy differences in side effects were found between Ozempic and Trulicity.

Although Ozempic was found to be more effective than Trulicity, it is important to note that people respond to medications differently. This means some people will get better results from Trulicity and some from Ozempic.

Natural alternatives to Trulicity

According to a 2021 study, tea, berberine, curcumin, wheat, cinnamon, soybean, gardenia, and resveratrol may all boost GLP-1 levels in your body naturally and work as natural alternatives to Trulicity.

You shouldn’t stop using prescription drugs in favor of natural alternatives without speaking with your healthcare provider first. Natural alternatives aren’t generally as effective as prescription diabetes drugs.

Is Trulicity safe with caffeine?

No direct interactions have been found between Trulicity and caffeine. Speak to your doctor if you are concerned about caffeine consumption while using Trulicity.

Creon alternatives: which other EPI medications can I take?

Creon is an FDA-approved brand-name medication manufactured by Abbott Laboratories. It is classified as a pancreatic enzyme replacement therapy (PERT) and is used to help digest food by breaking down fats, starches, and proteins in your food.

Creon is an expensive brand-name medication with several alternatives available, including medications with lower-cost generic alternatives. Learn more about what Creon is, how it works, its side effects, and its alternatives.

What is Creon?

Creon is a pancreatic enzyme product containing a combination of porcine-derived lipases, proteases, and amylases as active ingredients. It can treat conditions such as cystic fibrosis, chronic pancreatitis, pancreatectomy, and pancreatic cancer, where your pancreas does not produce or release enough enzymes.

Creon releases high levels of lipase, amylase, and protease into the duodenum following activation by its alkaline pH. This facilitates the breakdown of fats into glycerol and free fatty acids, starches into dextrins and sugars, and proteins into amino acids and peptides. The effectiveness of Creon depends on several factors, such as the dose, your gastrointestinal pH, and the microsphere size of the medication.

RELATED: What is Creon

What are the most common side effects of Creon?

The most common possible side effects of Creon include:

  • Abdominal pain
  • Cramping
  • Headache
  • Hyperglycemia, or hypoglycemia
  • Bloating, flatulence
  • Vomiting
  • Frequent bowel movements, constipation
  • Dizziness
  • Cough, sore throat
  • Weight loss

Some serious side effects of Creon include:

  • Fibrosing colonopathy (scarring of your colon)
  • Worsening of a long-term pancreas problem
  • Increase in uric acid levels
  • Viral infection
  • Allergic reactions (hives, face swelling, throat tightness, trouble breathing)

If you experience any of these serious side effects, stop taking Creon and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the most commonly prescribed doses of Creon?

  • Delayed-Release Capsule – 3,000/units of lipase; 9,500/U of protease; and 15,000/U of amylase
  • Delayed-Release Capsules: 6,000/units of lipase; 19,000/U of protease; and 30,000/U of amylase
  • Delayed-Release Capsules: 12,000/units of lipase; 38,000/U of protease; and 60,000/U of amylase
  • Delayed-Release Capsules: 24,000/units of lipase; 76,000/U of protease; and 120,000/U of amylase
  • Delayed-Release Capsules: 36,000/units of lipase; 114,000/U of protease; and 180,000/U of amylase

RELATED: Creon Dosage

How to take Creon

  • Take Creon exactly as your healthcare provider tells you. Do not take more Creon capsules in a given day than the number your healthcare provider tells you to take (total daily dose). Your doctor may change your dose based on your body weight or the amount of fatty foods you eat.
  • You should not switch Creon with other pancreatic enzyme products without talking to your doctor.
  • Take Creon with a  snack or meal. If you eat a lot of snacks or meals, make sure you don’t exceed your total daily dose.
  • Do not chew or crush Creon capsules or their contents. Do not hold the capsule or its contents in your mouth. This can irritate your mouth or change how Creon works in your body.
  • For infants or patients unable to swallow capsules whole, the contents can be sprinkled on soft acidic foods like applesauce at room temperature. The mixture should be swallowed immediately without chewing it. Follow with water or juice to be sure there is no Creon left in the mouth.
  • If you miss a dose of Creon, the next dose should be taken with your next snack or meal as directed. Do not double your dose or take extra Creon to make up for the missed dose.
  • Read the Instructions for Use and Medication Guide that comes with your Creon prescription.
  • Store Creon at room temperature between 59°F to 77°F (15°C to 25°C). You may store Creon between 77°F to 104°F (25°C to 40°C) for up to 30 days. Keep Creon in its original container in a dry place. Keep the bottle tightly closed between uses to protect it from moisture.

How long does Creon last?

The enzymes within Creon should be active for up to one hour. You will need to take another dose of Creon if you eat after more than 1 hour after taking Creon.

What happens if you stop taking Creon?

If you do not take your Creon capsules with each meal, your symptoms may become worse. If you discontinue taking Creon for a long time, you will not have enough pancreatic enzymes to digest the food and absorb the vital nutrients, vitamins (vitamins A, D, E, and K), or the calories available, leading to potential weight loss. This is known as malabsorption.

Foods to avoid when taking Creon

You may need to make changes to your diet when taking Creon. Foods high in fat, protein, and carbohydrates may be difficult to digest and can make your symptoms worse. You should avoid:

  • Foods rich in fiber, such as lentils, barley, and brown rice
  • Fried food
  • Processed meats
  • Alcohol
  • Large meals – avoid large meals, instead eat 3 to 5 small meals each day

Speak to your healthcare provider or dietitian about which foods you should or shouldn’t eat while using Creon. They will be able to help you create a healthy balanced diet plan that meets your dietary needs.

RELATED: What foods to avoid when taking Creon

Creon alternatives

What are the best pancreatic enzymes to take?

Creon is a pancreatic enzyme supplement containing a combination of lipase, amylase, and protease. There are other pancreatic enzyme products that your healthcare professional can prescribe if Creon is not the right medication for you. The U.S. Food and Drug Administration has approved the following pancreatic enzyme supplements:

  • Pancreaze (pancrelipase)
  • Viokase (pancrelipase)
  • Ultresa (pancrelipase)
  • Zenpep (pancrelipase)
  • Pertzye (pancrelipase)

Are Creon and Zenpep the same?

Zenpep, in comparison to Creon, is similar in terms of its effectiveness and safety for the treatment of adults and adolescents with cystic fibrosis-associated exocrine pancreatic insufficiency.

Zenpep contains a mixture of digestive enzymes (including proteases, lipases, and amylases) obtained from pig pancreases. It is used to help those patients with exocrine pancreatic insufficiency digest food and the fats, proteins, and sugars in the food.

Natural substitutes for Creon

Natural substitutes to Creon therapy for exocrine pancreatic insufficiency involve maintaining a healthy diet. As discussed previously, there are certain foods you should avoid. You should also make sure you drink plenty of fluids, eat small, healthy meals more often, use dietary supplements, avoid a high-fiber diet, and avoid drinking alcohol.

Why is Creon so expensive?

Creon is a brand-name medication currently not available in a generic form. Branded medications generally are more expensive, mostly due to the manufacturers who have researched, developed, and produced the drug re-couping their costs.

Is there a generic for Creon?

Creon is only available as a brand-name medication and is not currently available in a generic version. (A generic version or generic drug is a copy of the brand-name medication that contains the same active ingredient as the brand-name medication).

Cheaper alternatives to Creon

Cheaper branded alternatives are available to Creon. These include Viokace, which is around half the price to that of Creon, and Pancreaze and Pertzye, which are around 80 % cheaper than Creon. Exactly how much you pay for your medication will depend on where you buy it from and the quantity you buy.

Over-the-counter Creon vegetarian alternatives

Over-the-counter enzyme products from plant sources are available. Hi-Vegi-Lip is a vegetable-based product that is claimed to contain digestive enzymes.

It is important to understand that over-the-counter natural alternatives do not follow the same standards and guidelines required by the FDA for prescription drugs. These over-the-counter products may not necessarily contain the active ingredients or treat the condition they claim to. Always speak to your healthcare provider for medical advice before starting any treatments for a medical condition.

Diabetes drug for weight loss: does it work?

Obesity is a disease within the adult population in the United States that has increased to almost 42% of the population. The highest rates of almost 50% are found in non-Hispanic Black adults and around 46% in Hispanic adults. People with obesity have been shown to be at an increased risk of other serious weight-related comorbidities such as certain types of cancer, cardiovascular disease, heart disease, strokes, hypertension (high blood pressure), metabolic disorders, and an increased risk of developing diabetes. Obesity increases blood glucose levels due to insulin resistance. Obesity has also been seen to affect the quality of life and negatively impact mental health.

Certain diabetes medications have been shown to help improve blood sugar control and cause weight loss. Here we will take a look at some of the treatments available for diabetes and how they help with weight loss.

Which diabetes drug is FDA-approved for weight loss?

Wegovy (semaglutide) and Saxenda (liraglutide), both manufactured by Novo Nordisk, are the only two brand-name diabetes drugs FDA-approved for weight management in the U.S. They both belong to the class of weight loss medications called glucagon-like peptide 1 receptor agonists (GLP-1).

Wegovy is a prescription drug approved for weight loss in adults 18 years of age and over with a body mass index (BMI) of 30 or above, or a BMI of 27 plus an associated medical condition such as high cholesterol or high blood pressure.

Saxenda is used in adults and children 12 years of age and older, along with diet and exercise for chronic weight management.

What diabetes drugs help with weight loss?

Treatments for diabetes may belong to different classes of drugs and may not all share the same mechanism of action or side effects. Certain diabetes drugs, but not all, may cause weight loss.

Treatments for diabetes that cause weight loss as a side effect include:

While some of these treatments are now FDA-approved for weight loss, others, such as metformin, are not. Metformin may be used off-label (prescribed outside of its intended FDA-approved purpose) for weight management in people without type 2 diabetes.

Once a week injections for diabetes and weight loss

The only medications available as once-a-week injections for diabetes are the GLP-1 class of medications. All GLP-1 drugs can cause weight loss. However, not all GLP-1 agonists are FDA-approved for weight loss in the U.S. GLP-1 weekly injections include:

  • Wegovy (semaglutide) – the only FDA-approved (Food and Drug Administration) weekly injection for weight management in the U.S.
  • Trulicity (dulaglutide) – used in combination with diet and exercise to treat type 2 diabetes in adults
  • Ozempic (semaglutide) – used with diet and exercise in adults to treat type 2 diabetes
  • Bydureon Bcise (exenatide) – used to help control blood sugar levels in patients with type 2 diabetes
  • Tanzeum (albiglutide) – used in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • Byetta (exenatide) – also used in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • Mounjaro (tirzepatide) a once-weekly glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, the only FDA-approved dual-action GIP and GLP-1 receptor agonist for the treatment of diabetes

RELATED: GLP-1 medications: do they work for weight loss?

What is the best diabetes drug for weight loss in 2022?

Currently, the best and only FDA-approved diabetic drugs for weight loss are Wegovy and Saxenda. There is however another treatment, not currently available for weight loss but under review, called Mounjaro (tirzepatide). Obese or overweight non-diabetic individuals who took Mounjaro lost around 20% of their body weight at the highest doses.

New diabetes drug for weight loss

The US Food and Drug Administration approved tirzepatide to treat type 2 diabetes in May 2022, to Eli Lilly & Co. under the brand name Mounjaro. Mounjaro is a new drug approved as a therapy to reduce glucose in patients with type 2 diabetes.

Patients participating in the SURMOUNT-1 clinical trial on a dose of 15mg of tirzepatide were seen to experience a 22.5% reduction in their body weight. Based on these findings, the FDA granted tirzepatide a “fast track” review as a treatment for obesity. Lilly will use data from the SURMOUNT-1 and ongoing SURMOUNT-2 trial to investigate the use of tirzepatide in patients being treated for type 2 diabetes who also have obesity or excess weight.

Diabetes drug for weight loss semaglutide

Semaglutide is available under the brand names Ozempic, Rybelsus and Wegovy. It is classed as a GLP-1 agonist antidiabetic medication for the treatment of type 2 diabetes and for the long-term management of obesity.

Wegovy (semaglutide) and Saxenda (liraglutide) are the only two brand-name GLP-1 receptor agonists, both manufactured by Novo Nordisk that are currently FDA-approved (Food and Drug Administration) for weight management in the U.S.

Is Ozempic for weight loss?

No. The U.S. Food and Drug Administration has approved Ozempic in combination with diet and exercise to help control blood sugar levels in patients with type 2 diabetes.

The active ingredient semaglutide in Ozempic causes your pancreas to produce more insulin, helping to control blood sugar levels and also to reduce the release of glucagon, a hormone that would normally increase your blood sugar levels. This combined effect of semaglutide can cause weight loss. Ozempic is not FDA-approved for weight loss, but Wegovy, which also contains semaglutide is FDA-approved for weight loss in the U.S.

RELATED: Ozempic for weight loss

How much weight will I lose on Ozempic?

As previously stated, Ozempic is not approved in the U.S. for weight loss. However, weight loss is a side effect experienced when using Ozempic in combination with diet and exercise for the treatment of type 2 diabetes. Weight loss has the benefit of reducing the potential for developing other medical conditions such as high blood pressure, heart disease, and stroke.

People who will see the greatest weight reductions are those supported by a healthcare professional. By making lifestyle changes such as changes to diet and increasing exercise, the benefits of using Ozempic are greatly increased. Most people will lose around 5% of their body weight, with around a third losing 10% or more.

Ozempic side effects

The most common side effects of Ozempic in clinical trials compared to placebo include nausea, vomiting, stomach (abdominal) pain, constipation, diarrhea, and weight loss. More serious side effects of Ozempic include risk factors such as thyroid tumors, including cancerous tumors, diabetic retinopathy, gallbladder problems, kidney problems, including kidney disease and failure, severe allergic reactions to the medication that can cause itching, rashes, swelling, and difficulty breathing, inflammation of your pancreas (pancreatitis), changes in your vision, and very low blood sugar levels (hypoglycemia).

These are not all the side effects Ozempic may cause. You will find more details in the patient leaflet that comes with your medication. If you have any concerns about the side effects of Ozempic, talk to your physician or pharmacist for medical advice.

Why is Ozempic so hard to get?

Unfortunately, Ozempic has recently gained media attention as celebrities, and TikTok influencers have posted online describing using Ozempic to lose weight quickly. Ozempic has become the subject of some controversy as it has gone viral on social media as a miracle treatment for weight loss, even for non-diabetics. This surge of demand has caused shortages of the medication, creating serious issues in supply for individuals who require Ozempic to manage their diabetes.

The medical advice is that you should not take Ozempic unless prescribed by a doctor who can supervise your diabetes management and monitor your diabetes care. People who are prescribed Ozempic but stop using it are seen to regain any weight that was lost, especially if lifestyle changes were not made. If you are considering or are concerned about obtaining Ozempic speak to your healthcare provider for safe medical advice.

To address drug shortages with Ozempic, Mounjaro and other popular GLP-1 medications, NiceRx also offers Compounded Semaglutide injections and Compounded Tirzepatide injections.

Diabetes drug FAQs

Can diabetes cause rapid weight loss?

Yes. People with diabetes may have inadequate levels of insulin, preventing the body from getting glucose from the blood into cells to use as energy. This can cause the body to start burning fat and muscle to provide energy. This can cause a decrease in your overall body weight.

How can I stop weight loss from diabetes?

The safest way to prevent weight loss from diabetes is to gain weight by following a healthy balanced diet. This will ensure that calorie and nutrient intake will be sufficient. Eating fatty and other high-calorie foods will not give healthy weight gain.

How much weight do you lose when you are diabetic?

The weight loss experienced will vary from person to person, depending on your starting weight, your condition, and the treatments you are using. Losing around 5% of body weight can be beneficial to your health, and obese patients are more likely to reverse their diabetes if they lose more weight.

Why is losing weight a problem for diabetes?

Weight loss in diabetes is most often positive, but weight loss may mask an underlying health issue. Always discuss any weight loss with your doctor to ensure it is safe and not due to other medical conditions.

How much weight should I lose?

You should aim to lose 1 to 2 pounds a week through a reduced-calorie diet and regular physical activity.

How does weight loss affect diabetes?

Losing weight will give you more energy and reduce your risk of other serious medical conditions such as heart disease and stroke, as well as help to control your blood sugar levels and your diabetes. Losing weight in diabetes may even cause remission of your diabetes.

Why do people with diabetes lose weight?

With diabetes, the sugar in your blood may not enter the cells in your body that need it for energy. Because of this, your body burns fat and muscle for energy instead, resulting in what may seem to be unexplained weight loss.

What are the signs of diabetes?

The most common types of diabetes are Type 1 and Type 2 diabetes. Common signs of diabetes include urinating frequently, feeling thirsty, tiredness, losing weight, thrush and genital itching, problems with your eyesight, and increased hunger. If you experience these symptoms, speak to your doctor for medical advice.

RELATED: Early signs of diabetes

What is the best way to lose weight with diabetes?

The healthiest and safest way to lose weight with diabetes is to discuss a healthy eating plan with a dietitian. There are a number of diet plans you can discuss which may be of benefit to you. These include a low-carb diet or the Mediterranean diet plan. Having a long-term healthy eating plan in combination with exercise is the best way to lose weight and maintain a healthy body weight.

How can I change my diet to prevent weight loss from diabetes?

If you have diabetes or prediabetes, see a dietitian or diabetes educator to develop a healthy diet plan. The American Diabetes Association also offers advice and suggests meal planning. Healthy food options include:

  • Nonstarchy vegetables, such as spinach, carrots, and tomatoes
  • Tuna, lean pork, or chicken for protein
  • Whole-grain foods, such as brown rice, or starchy vegetable, such as green peas
  • Nuts or avocados
  • Fruit
  • Dairy
  • Unsweetened tea or coffee
  • Healthier carbohydrates
  • Less salt
  • Less alcohol

Making simple changes to your diet will not only help prevent weight loss but will also ensure you get all the essential vitamins, minerals, and supplements you require to maintain a more balanced and healthy lifestyle.

RELATED: What foods to avoid with diabetes

GLP-1 medications: do they work for weight loss?

Obesity, a chronic disease within the adult population in the United States, has increased to almost 42% of the population. The highest rates of almost 50% are found in non-Hispanic Black adults and around 46% in Hispanic adults. People with obesity have been shown to be at an increased risk of other serious weight-related comorbidities such as certain types of cancer, heart disease, strokes, hypertension (high blood pressure), metabolic disorders, and an increased risk of developing diabetes. Obesity has also been seen to affect the quality of life and negatively impact mental health.

Certain type 2 diabetes medications have been shown to help improve blood sugar control and cause weight loss. This class of weight loss medications is called glucagon-like peptide 1 receptor agonists (GLP-1). Wegovy (semaglutide) and Saxenda are (liraglutide) the only two brand-name GLP-1 receptor agonists, both manufactured by Novo Nordisk that are FDA-approved (Food and Drug Administration) for weight management in the U.S.

Here we will look at these GLP-1 drugs in more detail and answer some of the more commonly asked questions.

Do GLP-1 drugs work for weight loss?

GLP-1 incretin hormones help lower your blood glucose levels when you digest food in three ways. They:

  • Stimulate your body to produce more insulin to help lower blood sugar levels
  • Prevent the release of glucagon
  • Slow down how quickly food from the stomach moves into the small intestine, causing you to feel fuller for longer and to eat less

GLP_1 drugs are more active when you have eaten and are less active when you stop. This helps to prevent blood glucose levels from falling too low and causing hypoglycemia. GLP-1s have added benefits in that they also reduce the risk of heart diseases, such as heart failure and stroke, and improve blood pressure and cholesterol levels.

What are the GLP-1 medications?

Medications for diabetes and insulin help to reduce blood sugars but may also cause weight gain. All GLP-1 drugs can cause weight loss. However, not all are FDA-approved for weight loss, specifically in the U.S. GLP-1 medications include:

  • Trulicity (dulaglutide) – used in combination with diet and exercise to treat type 2 diabetes in adults
  • Saxenda (liraglutide) – FDA-approved for weight management in the U.S. and can lead to a weight loss of between 10 to 16 pounds
  • Victoza (liraglutide) – FDA-approved for use with a healthy diet and exercise to lower blood sugar levels in patients 10 years of age and older with type 2 diabetes. It is also used to reduce heart attacks and stroke in type 2 diabetic patients with heart disease
  • Ozempic (semaglutide) – used with diet and exercise in adults to treat type 2 diabetes
  • Rybelsus (semaglutide) – used with diet and exercise to lower blood sugar levels in adults with type 2 diabetes mellitus
  • Wegovy (semaglutide) – FDA-approved (Food and Drug Administration) for weight management in the U.S.
  • Bydureon Bcise (exenatide) – used to help control blood sugar levels in patients with type 2 diabetes
  • Tanzeum (albiglutide) – used in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • Byetta (exenatide) – also used in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • Mounjaro (tirzepatide) a once-weekly glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, the only FDA-approved dual-action GIP and GLP-1 receptor agonist for the treatment of diabetes
  • Compounded Semaglutide
  • Compounded Tirzepatide

Which GLP-1 works best for weight loss?

In clinical trials, liraglutide was compared with semaglutide in adult patients without diabetes with a body mass index (BMI) of 30 or more.

It was found that liraglutide 3.0 mg daily caused a mean weight loss of around 8% at week 52 of the trial, while semaglutide 0.2 mg, 0.3 mg, and 0.4 mg caused an average weight reduction of between 11 to 14%. The average weight loss in the trial was slightly above 2% in the placebo group.

The weight loss seen when using semaglutide is greater than when using other classes of antiobesity medications:

  • Orlistat (6%)
  • Lorcaserin (6%)
  • Phentermine-topiramate (8%-10%)
  • Naltrexone-bupropion (5%)

5% to 10% of initial weight is defined as significant weight loss. This is the point at which an improvement in risk factors for cardiovascular disease is seen.

Once-weekly use of semaglutide also helps to improve compliance and quality of life, compared to once-daily administration. This has been seen when using GLP-1 agonists for the management of weight loss as well as for other long-term diseases.

What is the recommended dosage of GLP-1 for weight loss?

Liraglutide was originally approved by the FDA in 2015 as the first GLP-1 agonist for chronic weight management in obese or overweight adults. This was subsequently updated in Dec 2020 to include liraglutide for the treatment of obesity in adolescents between 12 to 17 years of age

The starting dose of liraglutide is 0.6 mg once each day for 1 week and increased weekly to a maintenance dose of 3 mg once each day. Liraglutide is administered as a subcutaneous injection daily. It is long-acting with a half-life (the time it takes for half of the active drug to be eliminated from your body) of between 12 to 15 hours.

Wegovy (once-weekly semaglutide) was FDA-approved in June 2021 for chronic weight management in obese or overweight adults. The initial starting dose of semaglutide is 0.25 mg once weekly, also administered as a subcutaneous injection. The dose of semaglutide is increased every 4 weeks to a maintenance dose of 2.4 mg.12 Semaglutide has a half-life of around 1 week, which means it may be administered once a week.

You are advised to read the prescribing information provided with your medication for the complete drug information.

How long does it take to lose weight on GLP-1?

GLP-1s are most effective for weight loss when used in combination with lifestyle changes such as changes to diet, an increase in physical activity, improved sleep quality, and emotional health.

Those following these lifestyle interventions while using GLP-1 medications will lose at least 5% of their body weight within 3 months and a reduction in body fat percentage. At 6 months, patients may lose at least 10% of body weight.

What are the side effects of GLP-1?

GLP-1 drugs are generally administered as an injection, and side effects may occur. The more common side effects you experience with GLP-1 drugs will often improve as you use the treatment. Some of the more common side effects in clinical trials compared to placebo include:

  • Gastrointestinal side effects such as nausea, vomiting, constipation, or diarrhea
  • Abdominal pain
  • Headache, dizziness
  • Fatigue
  • Dyspepsia, abdominal distension, eructation
  • Hypoglycemia (low blood sugar) in patients with type 2 diabetes
  • Flatulence, gastroenteritis, and gastroesophageal reflux disease (heartburn)

Hypoglycemia (low blood sugar levels), a more serious side effect of GLP-1 drugs, may also occur. The risk of this increases if you also take other drugs known to reduce blood sugar levels at the same time, such as insulin or sulfonylureas.

While the majority of patients take these medications without any serious complications, they do carry a black box warning concerning the possible increased risk of medullary thyroid carcinoma. This comes from animal studies and was not replicated during placebo-controlled clinical trials. In rare instances, GLP-1 drugs can cause more serious side effects. These can include:

  • Acute pancreatitis
  • Acute gallbladder disease
  • Acute kidney injury – monitor renal function when initiating or escalating doses if severe adverse gastrointestinal reactions occur
  • Hypersensitivity
  • Diabetic retinopathy complications in patients with type 2 diabetes
  • Heart rate increase
  • Suicidal behavior and ideation

Your doctor will assess the benefits of using GLP-1 medications against your risk of adverse effects. You are encouraged to report adverse events or adverse reactions to GLP-1 drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

GLP-1 FAQs

Can I take Ozempic for weight loss if I’m not diabetic?

No. Ozempic is currently only FDA-approved for the treatment of type 2 diabetes mellitus to help improve the control of blood sugar levels and to reduce the risk of cardiovascular problems in patients with Type 2 diabetes and cardiovascular disease.

RELATED: Ozempic for weight loss

Can you drink alcohol while on GLP-1?

In more recent years, alcohol-related behavior has been linked to gut-brain peptides, which are known to control appetite and food intake. These gut-brain peptides include peptide glucagon-like peptide-1 (GLP-1). Interestingly, it has been shown in trials that GLP-1 inhibitors increase alcohol consumption, and GLP-1 receptor agonists reduce alcohol consumption in patients with type-2 diabetes mellitus. These studies raise the question that GLP-1 receptor agonists need to be tested further as potential treatments for those with alcohol addiction as well as other addictive disorders.

The general advice currently, however, is to avoid drinking alcohol while using GLP-1 treatments, as drinking alcohol increases the risk of side effects such as hypoglycemia. This may not always be a realistic target, and as such, you are advised to discuss your alcohol consumption with your healthcare provider if you are using GLP-1 medications.

What naturally increases GLP-1?

Glucagon-like peptide-1 is a gastrointestinal hormone released by L cells in the body in direct response to food intake, with the release of GLP-1 in the body being mainly stimulated by glucose and fatty acids. Excessive intake of sugar and fat can cause the development of obesity and diabetes.

Food factors that release GLP-1, such as dietary peptides and non-nutrients, are seen as desirable to improve glucose tolerance. Studies in humans and animals have shown that proteins/peptides in the diet will help to stimulate the secretion of GLP-1 and that dietary amino acids, peptides, and phytochemicals (quercetin), can all stimulate GLP-1 secretion.

These food factors improve the breakdown of glucose and increase the secretion of GLP-1. Some of these dietary peptides also reduce the activity of plasma peptidase, which inactivates GLP-1. Using food factors that will help to release or stimulate GLP-1 activity may potentially be a way to prevent and treat obesity and diabetes.

Can non-diabetics take GLP-1?

The US Food and Drug Administration has currently approved 6 drugs for the long-term treatment of obesity in the U.S. These include lorcaserin, naltrexone/bupropion, phentermine/topiramate, orlistat, and the glucagon-like peptide-1 analogues liraglutide, and semaglutide.

GLP-1 agonists increase insulin secretion and block the release of glucagon only when glucose levels increase in the body and can be used in non-diabetic patients suffering from obesity without causing low blood sugar levels.

Liraglutide and semaglutide are approved in combination with a reduced-calorie diet and increased physical activity for chronic weight management under the brand names Saxenda and Wegovy.

Who should not take GLP-1?

GLP-1 drugs are not recommended if you are allergic to the active ingredients semaglutide or liraglutide if anyone in your family has had a type of thyroid cancer called medullary thyroid carcinoma (MTC), if you have an endocrine system condition called multiple endocrine neoplasia syndrome type 2 (MEN 2), if you have pancreatitis, type 1 diabetes, or are under 18 years of age.

Do you have to take GLP-1 forever?

GLP-1 are intended for long-term use, and it is important you take them for as long as your doctor advises you to do so. Do not stop using this medication without medical advice, and discuss any side effects you may experience with your healthcare provider when taking this treatment.

Is GLP-1 an appetite suppressant?

GLP-1 is not an appetite suppressant as such. GLP-1 treatments delay gastric emptying and promote the feeling of fullness and satiety and therefore reduce food intake, appetite and food cravings. These combinations of effects lead to weight loss through a reduction in food consumption and energy intake.

Is GLP-1 the same as insulin?

Unlike other treatments for type 2 diabetes, Ozempic (semaglutide) and Victoza (liraglutide) are not types of insulin. They are human hormones that act on different parts of your body. Semaglutide and liraglutide encourage your pancreas to produce more insulin, helping to lower your blood sugar after you’ve eaten. They also appear to increase the growth of the cells in your pancreas that produce insulin (beta-cells).

Can you take GLP-1 receptor agonists while you are pregnant or breastfeeding?

Animal reproduction studies have shown there may be potential risks to the fetus if these medications are used during pregnancy. You should stop taking these drugs as soon as you find out you’re pregnant or at least 2 months before a planned pregnancy.

It is not known if these medications are found in breast milk. You should discuss the risks of using these medications during lactation with your healthcare provider.

Is the GLP-1 injection painful?

GLP-1 injections may be painful. To help prevent this, the injections are given in parts of the body containing fewer pain receptors. This would normally be areas such as the upper arm, thigh, or abdomen. You are also advised to rotate injection sites and not to inject in the same area of skin each time. This will help to prevent side effects such as lipohypertrophy (skin thickening under the skin).

Do you need a prescription for GLP-1?

Yes. Talk to your healthcare provider about your diabetes care options and if you need a GLP-1 prescription. Diabetes and obesity are challenging, long-term medical conditions, and you will need professional support and advice from your healthcare provider.

What is the difference between Victoza and other GLP-1s?

The main points to remember are that Victoza is used as an adjunct to improved diet and exercise to help manage high blood sugar levels in people aged 10 years of age and older with type 2 diabetes and also to reduce the risk of certain heart problems in adults with type 2 diabetes and heart disease. Victoza is not FDA-approved as a weight loss drug. Also, Victoza is administered subcutaneously once daily and not once weekly.

What is the difference between Victoza and Ozempic?

Both Ozempic and Victoza are given as subcutaneous injections under your skin. The main difference between the two is how often you use them. Ozempic is injected once weekly, while Victoza is injected once daily.

Ozempic is considered better than Victoza at reducing HbA1C and weight. However, Ozempic also causes more stomach-related side effects than Victoza.

RELATED: Ozempic vs Victoza

Quviviq side effects and how to avoid them

Quviviq is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Idorsia Pharmaceuticals Ltd. Quviviq is an orexin receptor antagonist used for the treatment of adult patients with insomnia and with difficulties with sleep onset or sleep maintenance. While Quviviq is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Quviviq include headaches and tiredness. Less common but more serious side effects can include worsening suicidal thoughts and behavior.

Learn more about the side effects of Quviviq and what you can do to avoid them.

What is Quviviq (daridorexant)?

Quviviq contains daridorexant, a sedative-hypnotic as the active ingredient. Daridorexant is a dual orexin receptor antagonist. It works by blocking the action of the neuropeptide orexin, a chemical produced by the brain that promotes wakefulness. This allows people to fall asleep quicker, stay asleep for longer, and to improve functioning during the day.

Is Quviviq addictive?

Quviviq may cause addiction, especially if you have a substance use disorder. Discuss your treatment plan with your doctor to ensure you take this medication safely.

Is Quviviq a narcotic?

Quviviq is not a narcotic. It belongs to a class of drugs called dual orexin receptor antagonists (DORAs). However, Quviviq is a federally controlled substance as it can be abused and lead to addiction.

Is Quviviq safe?

Quviviq may affect your ability to drive safely and think clearly. Speak to your doctor to discuss the side effects of Quviviq and how to take it safely.

What is the safest sleeping pill for the elderly?

First-line treatment in the elderly is nonbenzodiazepines (such as zolpidem and zaleplon). These are safer than older treatments such as antihistamines, tricyclic antidepressants, and benzodiazepines.

Quviviq dosage

Quviviq is available in tablet form in the following doses: 25 mg and 50 mg.

The recommended dosage is 25 mg to 50 mg at night, taken 30 minutes before going to bed, with at least 7 hours remaining to planned awakening. The maximum recommended dosage is 25 mg once per night if you have hepatic impairment. Quviviq is not recommended if you have severe hepatic impairment.

Please read the full prescribing information and medication guide for the complete drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How many days does it take for Quviviq to work?

Quviviq normally works within 30 minutes of taking it but may take longer if you take it with or after food.

Quviviq side effects

The most common side effects of Quviviq in clinical trials compared to placebo include:

  • Headache
  • Somnolence (daytime sleepiness)
  • Fatigue

In rare instances, Quviviq can cause more serious side effects. These can include:

  • CNS-depressant effects – daytime impairment, motor coordination including morning impairment. Caution is advised with next-day driving
  • Worsening depression and suicidal thoughts
  • Sleep paralysis, hypnagogic/hypnopompic hallucinations, and cataplexy-like symptoms
  • Complex sleep behaviors – sleepwalking, sleep-driving, and engaging in other activities while not fully awake
  • Compromised respiratory function

If you experience any of these serious side effects, stop taking Quviviq and seek medical attention immediately. You are encouraged to report the adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Quviviq cause weight gain?

Weight gain or weight loss are not reported side effects of Quviviq. Speak to your doctor if you experience changes in weight while using Quviviq.

Quviviq drug interactions

Quviviq can interact with other medications, including:

  • Moderate or strong CYP3A4 inhibitors
  • Moderate or strong CYP3A4 inducers
  • Azole antifungals (such as itraconazole, ketoconazole)
  • Certain HIV protease inhibitors (such as indinavir)
  • Rifampin
  • Opioid pain or cough relievers (codeine, hydrocodone), alcohol, marijuana
  • Other drugs for sleep or anxiety (alprazolam, zolpidem)
  • Muscle relaxants (carisoprodol, cyclobenzaprine)
  • Antihistamines (cetirizine, diphenhydramine) – may increase the risk of side effects such as shallow breathing, severe drowsiness, or dizziness

This list is not exhaustive, and other prescription drugs may interact with Quviviq. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Quviviq warnings & precautions

You should not use Quviviq if you:

  • Are allergic to the active ingredient daridorexant
  • Are allergic to any of the other ingredients in Quviviq
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Quviviq if you:

  • Are taking any of the medications that could interact with Quviviq
  • Have a sleep disorder (narcolepsy)
  • Have any sleep problems such as sleep apnea
  • Have chronic obstructive pulmonary disease (COPD)
  • Have a history of a sudden onset of muscle weakness
  • Have depression, or thoughts of suicide
  • Have a history of substance addiction
  • Have liver problems
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Quviviq, to make sure it is safe for you.

Quviviq vs zolpidem

At doses two or three times the maximum recommended dose, Quviviq has similar patient ratings to zolpidem (30 mg) and suvorexant (150 mg).

How to avoid Quviviq side effects

The best way to avoid side effects is to take Quviviq as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Quviviq that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Quviviq. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol or other CNS depressants while taking Quviviq, as it can increase your risk of drowsiness and daytime sleepiness.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Quviviq.

7. Know the signs and symptoms of Quviviq side effects

Signs and symptoms of side effects include headaches and fatigue. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Quviviq.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Quviviq as needed.

Kerendia side effects and how to avoid them

Kerendia is an FDA-approved brand-name medication manufactured by Bayer Pharmaceuticals, Inc. It is classified as a non-steroidal mineralocorticoid receptor antagonist (MRA) and is used to reduce the risk of sustained eGFR decline, end-stage kidney failure, cardiovascular death, heart attack, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease (CKD) associated with type 2 diabetes. While Kerendia is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Kerendia include low blood pressure. Less common but more serious side effects can include low potassium levels.

Learn more about the side effects of Kerendia and what you can do to avoid them.

Is Kerendia a diuretic?

Finerenone, the active ingredient in Kerendia, blocks mineralocorticoid receptors, making it a potassium-sparing diuretic.

Does Kerendia lower blood pressure?

Kerendia causes hypotension as a common side effect.

Kerendia dosage

Kerendia is available in tablet form in the following doses: 10 mg and 20 mg.

The manufacturer recommends a starting dose is 10 mg or 20 mg once per day based on the estimated glomerular filtration rate (eGFR) and serum potassium thresholds. Increase the dose after 4 weeks to the target dose of 20 mg once per day, based on eGFR and serum potassium thresholds.

If you are unable to swallow your tablet, you may crush it and mix it with water or other soft foods such as applesauce. After crushing and mixing the tablet, you should take your dose of Kerendia right away

If you forget to take a dose of Kerendia, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the normally scheduled time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

When is the best time to take Kerendia?

Take Kerendia with or without food once daily, as directed by your doctor.

Kerendia side effects

The most common side effects of Kerendia in clinical trials compared to placebo include:

  • Hypotension (low blood pressure)
  • Hyponatremia

In rare instances, Kerendia can cause more serious side effects. These can include:

  • Hyperkalemia – patients with decreased kidney function and higher baseline blood potassium levels are at increased risk, monitor serum potassium levels, and adjust the dose as needed

If you experience any of these serious side effects, stop taking Kerendia and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Kerendia drug interactions

Kerendia can interact with other medications, including:

  • Strong CYP3A4 inhibitors – concomitant use is contraindicated
  • Grapefruit or grapefruit Juice
  • Moderate or weak CYP3A4 inhibitors
  • Strong or moderate CYP3A4 Inducers
  • Consult with a physician before using potassium supplements or salt substitutes containing potassium

Before taking Kerendia, be sure to tell your healthcare provider about all of the medications you are taking to ensure they are safe to take at the same time.

Kerendia warnings & precautions

You should not use Kerendia if you:

  • Are allergic to the active ingredient finerenone
  • Have had an allergic reaction to any of the other ingredients in Kerendia
  • Are currently pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Kerendia if you:

  • Are taking any of the medications that could interact with Kerendia
  • Have adrenal insufficiency
  • Have renal impairment

You should always check with your doctor or pharmacist before taking any medication, including Kerendia, to ensure it is safe for you.

How to avoid Kerendia side effects

The best way to avoid side effects is to take Kerendia as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Kerendia that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Kerendia. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Kerendia.

6. Know the signs and symptoms of Kerendia side effects

Signs and symptoms of side effects include low blood pressure. If you experience these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Kerendia.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Kerendia as needed.

Mydayis side effects and how to avoid them

Mydayis is an FDA-approved brand-name medication manufactured by Shire, LLC. It is classified as a central nervous system (CNS) stimulant and is used to treat symptoms of attention deficit hyperactivity disorder (ADHD). The combination of amphetamine and dextroamphetamine is also sometimes used to treat narcolepsy. While Mydayis is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Mydayis include abdominal pain and loss of appetite. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Mydayis and what you can do to avoid them.

What is Mydayis?

Mydayis (amphetamine/dextroamphetamine) is a long-acting stimulant medication whose active ingredients consist of mixed amphetamine salts. It is approved by the U.S. Food and Drug Administration (FDA) to treat:

  • Attention Deficit Hyperactivity Disorder (ADHD) in patients 13 years and older.

Amphetamine products such as Mydayis are non-catecholamine sympathomimetic amines that work in the treatment of ADHD by increasing the release of the neurotransmitters dopamine and norepinephrine in your brain. The increase of these chemicals in the brain is thought to help increase your ability to pay attention, stay focused, and control your impulsivity and hyperactive behaviors. Amphetamines also trigger the release of epinephrine, serotonin, and histamine. It is not known if this contributes to relieving symptoms of ADHD.

How does Mydayis make you feel?

Mydayis may cause insomnia, loss of appetite, weight loss, nausea, irritability, dry mouth, anxiety, diarrhea, and an increased heart rate.

Mydayis dosage

Mydayis is available as extended-release capsules in the following doses: 12.5mg, 25mg, 37.5mg, and 50mg.

Mydayis is typically taken once daily in the morning right after waking up. You can take Mydayis with or without food, but you should take it the same way each time. You should swallow the Mydayis capsules whole. If you have difficulties swallowing, you can open up the capsule and sprinkle it over a spoonful of applesauce. The mixture should then be swallowed immediately without chewing. Do not store the Mydayis and applesauce mixture for later use.

If you miss a dose of Mydayis, skip the missed dose and take your dose the next morning at your regular time. Do not take Mydayis later in the day to make up for a missed dose. Your doctor may periodically stop your Mydayis treatment to check your ADHD symptoms.

If you think you or your child has taken too much Mydayis, contact your doctor or go to the nearest emergency room immediately. Symptoms of too much Mydayis include restlessness, tics (muscle twitches), rapid breathing, confusion, hallucinations, and muscle weakness.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Mydayis side effects

The most common possible side effects of Mydayis in clinical trials compared to placebo include:

  • Trouble sleeping
  • Abdominal pain
  • Loss of appetite
  • Weight loss
  • Nausea
  • Irritability
  • Dry mouth
  • Increased heart rate
  • Increased blood pressure
  • Anxiety

Mydayis can cause more serious long-term side effects, including:

  • Life-threatening allergic reactions, including angioedema, and trouble breathing
  • Serious heart problems such as chest pain and shortness of breath
  • New psychotic symptoms
  • Changes in sexual desire
  • Prolonged erections (in males)
  • Sudden death has occurred with the use of CNS stimulants such as Mydayis in pediatric patients with structural heart defects or other serious heart problems. Stroke, heart attack, and sudden death have also been reported in adults. Mydayis should be avoided in patients with structural heart abnormalities and other serious heart problems.
  • An increase in blood pressure and heart rate
  • Mental health issues such as psychosis or manic symptoms
  • Circulation problems, especially in the fingers and toes
  • Reduced seizure threshold
  • Mydayis use has a high potential for abuse and dependence

If you experience any of these serious side effects, stop taking Mydayis and seek medical attention immediately. You are encouraged to report adverse reactions of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Mydayis cause withdrawal symptoms?

Mydayis may cause withdrawal symptoms if stopped suddenly. Speak to your doctor if you experience side effects such as fatigue, anxiety, headaches, or depression.

Can Mydayis cause serotonin syndrome?

There is an increased risk of serotonin syndrome with Mydayis, especially if taken with other serotonergic drugs such as SSRIs and SNRIs. If this occurs, Mydayis should be discontinued, and you should seek immediate medical assistance.

Mydayis drug interactions

When Mydayis is taken with other drugs, it may change the way they work and may increase the frequency and severity of side effects. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take, including:

  • Antidepressants such as SSRIs (paroxetine), SNRIs, and MAOIs (tranylcypromine)
  • Omeprazole, esomeprazole, cimetidine, and other stomach medicines
  • Migraine medications such as triptans
  • Selegiline
  • Haloperidol
  • Fentanyl
  • Tramadol
  • Phenytoin
  • St. John’s wort

Before taking Mydayis, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Mydayis contraindications

Don’t take Mydayis if:

  • Known hypersensitivity to amphetamine formulations or any other ingredients in Mydayis.
  • Use of a monoamine oxidase inhibitor (MAOI) within the previous 14 days.

Talk to your doctor before taking Mydayis if you:

  • Heart problems, including defects or hypertension (high blood pressure)
  • Personal or family history of mental illness, including bipolar disorder, psychosis, depression, or suicidal thoughts or behaviors
  • Raynaud’s phenomenon (circulation problems in your fingers or toes)
  • History of seizures
  • Kidney disease
  • Thyroid disease
  • Glaucoma
  • Are pregnant, plan on becoming pregnant
  • Are breastfeeding, or are planning to breastfeed – Mydayis passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Mydayis, to make sure it is safe for you.

Is Mydayis better than Adderall?

Mydayis and Adderall are both Schedule II controlled substances and are both liable for drug abuse. They are both central nervous system stimulant medications for the treatment of ADHD. Mydayis will work for up to 16 hours, while Adderall will only last up to 12 hours.

Which is better Vyvanse or Mydayis?

Vyvanse and Mydayis are extended-release medications taken once daily to treat ADHD in adults. They are both FDA-approved for ADHD treatment in children; Mydayis for adolescents 13 years of age and older and Vyvanse for children 6 years of age and older.

While Vyvanse only contains 1 active ingredient, Mydayis is a combination of 4 ingredients. Because Vyvanse needs to be metabolized to work, its abuse potential is less than Mydayis. It also has fewer drug interactions. Mydayis and Vyvanse have not been compared directly in clinical studies, but individual studies have shown them to be effective in treating ADHD in adults and children.

How to avoid Mydayis side effects

The best way to avoid side effects is to take Mydayis as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Mydayis that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Mydayis. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Mydayis as it can increase your risk of side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Mydayis.

7. Know the signs and symptoms of Mydayis side effects

Signs and symptoms of side effects include abdominal pain and loss of appetite. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Mydayis may cause weight loss. If you experience this side effect while taking Mydayis, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Mydayis.

10. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Mydayis as needed.

Namzaric side effects and how to avoid them

Namzaric is a brand-name medication manufactured by Forest Laboratories, LLC. It is classified as a cholinesterase inhibitor and is used to treat dementia in people with moderate to severe Alzheimer’s disease. While Namzaric is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Namzaric include nausea and loss of appetite. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Namzaric and what you can do to avoid them.

What is Namzaric?

Namzaric is prescribed to treat moderate to severe dementia in adults who have Alzheimer’s disease. There’s no cure for Alzheimer’s disease, although medications can help slow the deterioration in brain function it causes. Namzaric can help prolong thinking, memory, and other areas of brain function if you have moderate to severe dementia.

How does Namzaric work?

Namzaric has two active ingredients, memantine hydrochloride and donepezil hydrochloride. Memantine hydrochloride helps your brain cells to send signals to each other. As Alzheimer’s causes protein plaques to build up in your brain, it makes it harder for your neurons to pass signals to each other. Memantine helps by stimulating the areas of your brain cells that receive signals, called receptors. This makes it easier for your brain cells to receive and send signals and helps preserve brain function. Memantine specifically targets receptors involved in learning and memory.

Donepezil hydrochloride (an acetylcholinesterase inhibitor) has a range of positive effects on your brain. Like memantine, it stimulates certain brain cell receptors, helping your brain cells send and receive signals. It also increases the number of certain neurotransmitters in your brain, chemicals that help your neurons send signals. Donepezil does this by blocking the enzymes that break down acetylcholine. This stops the enzymes from working and causes concentrations of acetylcholine to rise.

How does Namzaric help Alzheimer’s?

Namzaric may help to improve your memory and ability to perform daily tasks.

How effective is Namzaric?

Namzaric temporarily gives relief from the symptoms of Alzheimer’s. Namzaric does not prevent the cause of Alzheimer’s.

Namzaric dosage

Namzaric is available in capsule form in the following doses: 14 mg memantine hydrochloride extended-release capsule and 10 mg donepezil hydrochloride, and 28 mg memantine hydrochloride extended-release capsules and 10 mg donepezil hydrochloride

Namzaric comes as an oral capsule, taken once a day in the evening. Namzaric may be taken with or without food. If you are unable to swallow the capsules, you may sprinkle the contents on applesauce. If you miss a dose of Namzaric, you may skip the missed dose and take your next dose at the usual time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

When is the best time to take Namzaric?

Take Namzaric orally with or without food once daily just before bedtime.

Namzaric side effects

The most common possible side effects of Namzaric include:

  • Headaches
  • Diarrhea
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Dizziness
  • Loss of appetite (anorexia)
  • Bruising more easily

In some rarer instances, Namzaric can cause more serious side effects, including:

  • Severe allergic reactions – hives, swelling of your face or hands, mouth, lips, or throat, chest tightness, and trouble breathing
  • Stomach/intestinal bleeding such as black/bloody, tarry stools, vomiting blood or vomit that looks like coffee grounds, stomach pain, difficulty urinating
  • Muscle problems if you’re given anesthesia
  • A slow heart rate and fainting
  • An increase in stomach acid can lead to bleeding and ulcers
  • Seizures
  • Problems passing urine
  • A worsening of existing lung problems, like asthma

If you experience any of these serious side effects, stop taking Namzaric and seek medical attention immediately. You are encouraged to report the adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Can Namzaric cause confusion?

Overdose symptoms may cause confusion as well as severe dizziness, weakness, difficulty walking, fast or slow heart rate, sweating, agitation, unusual thoughts or behavior, hallucinations, shallow breathing, seizures, or fainting.

Does Namzaric cause withdrawal symptoms?

Do not stop using Nazmaric suddenly as this may make your condition worse.

Namzaric drug interactions

Namzaric can interact with other medications, including:

  • Any other Alzheimer’s disease medications
  • Any medications taken for heart conditions, like quinidine or beta-blockers
  • Any painkillers, like aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen
  • Any oral anticoagulants (blood thinners)
  • Anticonvulsants such as phenobarbital
  • Any barbiturates usually used to help you sleep
  • Any antifungal medications, like ketoconazole or itraconazole
  • Carbonic anhydrase inhibitors such as acetazolamide, methazolamide
  • Amantadine, taken to treat dyskinesia
  • Rifampin, used to treat tuberculosis
  • Carbamazepine or phenytoin, taken to treat epilepsy
  • Cimetidine or ranitidine, taken to treat heartburn and peptic ulcers
  • Dextromethorphan, used in cough medicines

Before taking Namzaric, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Namzaric warnings & precautions

Do not take Namzaric if you:

  • Are allergic to the active ingredients memantine hydrochloride or donepezil hydrochloride
  • Are allergic to any of the other ingredients in Namzaric
  • Are allergic to medications that contain piperidines
  • Are under 18 years of age

Talk to your doctor before taking Namzaric if you:

  • Are taking any of the medications that could interact with Namzaric
  • Have any heart problems (heart failure, slow heartbeat, QT prolongation in the EKG)
  • Have asthma or another lung problem
  • Have any kidney problems
  • Have any liver problems
  • Have any bladder problems
  • Have a stomach ulcer
  • Are planning to have a surgical, dental, or other medical procedure where anesthesia may be used
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Namzaric, to make sure it is safe for you.

How much does Namzaric cost?

Namzaric prices will vary depending on the amount you buy and where you buy it from. A pack of 28 10 mg-14 mg Namzaric capsules will cost between $510 to $550. Please note that this price is just a guide.

How to avoid Namzaric side effects

The best way to avoid side effects is to take Namzaric as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Namzaric that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Namzaric. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Namzaric as it can increase your risk of side effects such as dizziness.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Namzaric.

7. Know the signs and symptoms of Namzaric side effects

Signs and symptoms of side effects include nausea and loss of appetite. If you experience these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Namzaric may cause loss of appetite and weight loss. If you experience this side effect while taking Namzaric, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Namzaric.

10. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Namzaric as needed.

Neupro side effects and how to avoid them

Neupro is a brand-name medication manufactured by UCB, Inc. It is classified as a non-ergoline dopamine agonist and is used for the treatment of Parkinson’s Disease. While Neupro is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Neupro include problems with sleep. Less common but more serious side effects can consist of severe allergic reactions.

Learn more about the side effects of Neupro and what you can do to avoid them.

What is Neupro (rotigotine)?

Neupro contains the prescription medicine rotigotine, classed as a non-ergoline dopamine agonist. Rotigotine has a similar effect to dopamine, which is found naturally in your body.

Neupro patches are used for the treatment of:

  • Parkinson’s disease – a disease of the nervous system that can get worse over time. Symptoms of Parkinson’s include muscle stiffness, shaky or slow movement, with poor muscle control. It is thought to be linked to reduced amounts of dopamine in the brain.
  • Restless legs syndrome – symptoms are a twitching sensation in the leg muscles when sitting or lying down, once again linked to low levels of dopamine in the brain.

What does Neupro do for Parkinson’s?

Rotigotine is classed as a non-ergoline dopamine agonist. Dopamine agonists work by imitating the action of dopamine in the brain by binding to dopamine receptors that help to control the body’s ability to move properly.

Exactly how rotigotine works in the body for the treatment of Parkinson’s disease or restless legs syndrome is not fully understood. However, it is thought to be linked to rotigotine’s capacity to stimulate the dopamine receptors in the brain.

Is Neupro patch a narcotic?

Neupro is not a narcotic or a controlled substance. It is a dopamine agonist that works by stimulating dopamine receptors in your brain.

Neupro dosage

Neupro is available as a transdermal system patch: 1 mg/24 hrs, 2 mg/24 hrs, 3 mg/24 hrs, 4 mg/24 hrs, 6 mg/24 hrs, and 8 mg/24 hrs of rotigotine.

Neupro transdermal patches should be applied to clean, dry, hairless, and free of skin irritation patches of skin, where it will not be rubbed by tight clothing, on your stomach, thigh, hip, shoulder, or upper arm. The patch should be replaced with a new one every 24 hours. The new patch should be placed in a different place on your body. The same area of skin should not be used twice within 14 days.

Store patches at room temperature, away from moisture, heat, and direct light when showering or bathing. Apply a new patch if it falls off. If you miss a dose, apply a new patch as soon as you remember and replace the next patch at your usual time the next day, even if 24 hours have not passed.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

When is the best time to apply a Neupro patch?

Neupro patches may be applied at any time at the same time each day.

How quickly does Neupro work?

Neupro may take up to over 24 hours for your body to absorb the drug fully after your first dose.

Does Neupro cause withdrawal symptoms?

Suddenly stopping Neupro may cause withdrawal symptoms such as depression, anxiety, confusion, muscle stiffness, and fever.

Neupro side effects

The most common possible side effects of Neupro include:

  • Application site reactions
  • Nausea, vomiting
  • Headache, dizziness, problems with vision, feeling drowsy
  • Loss of appetite
  • Insomnia (sleep disorder where you have trouble sleeping)
  • Daytime sleepiness
  • Increased sweating
  • Rapid weight gain
  • Swollen hands or feet due to fluid retention

In rare instances, Neupro can cause more serious side effects. These can include:

  • Severe skin reaction that will not go away
  • Neupro contains sulfite, which can cause severe allergic reactions. Symptoms include chest pain, swelling of the lips or tongue, or trouble breathing or swallowing
  • Increased sexual urges, urges to spend money and binge eating
  • New or worsening mental status
  • Symptomatic postural and/or orthostatic hypotension
  • Increased heart rate
  • Feeling lightheaded or faint
  • Extreme drowsiness, suddenly falling asleep
  • Dyskinesia (problems controlling your muscles)

If you experience any of these serious side effects, stop taking Neupro and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Neupro drug interactions

Neupro can interact with other medications, including:

  • Dopamine antagonists, such as antipsychotics or metoclopramide
  • Tricyclic antidepressants – amisulpride, imipramine, trimipramine
  • Anesthetics – ketamine
  • Opioid pain relievers – propoxyphene
  • Treatment for narcolepsy ( sudden falling asleep) – sodium oxybate
  • Treatment for anxiety or muscle spasms – alprazolam, diazepam, lorazepam
  • Antidepressants – amitryptiline, citalopram, fluoxetine, paroxetine, venlafaxine
  • Treatment for muscle spasms – baclofen
  • Anti-convulsants – carbemazepine, phenobarbital, phenytoin
  • Treatments for mental health – clozapine, haloperidol, promazine
  • St. Johns wort – a herbal mental health treatment
  • Treatment for sleeping problems – zolpidem

Before taking Neupro, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Neupro warnings & precautions

You should not use Neupro if you:

  • Are allergic to the active ingredient rotigotine
  • Are allergic to any of the other ingredients in Neupro
  • Are breastfeeding or are planning to breastfeed – It is unknown if this drug passes into breast milk

Talk to your doctor before using Neupro if you:

  • Are taking any of the medications that could interact with Neupro
  • Have asthma
  • Have high or low blood pressure
  • Have any heart problems
  • Have kidney disease
  • Have mental health problems such as bipolar disorder, schizophrenia, or psychosis
  • Are wearing heating pads, electric blankets, saunas, heated water beds, and direct sunlight (this may increase the absorption of this medication into your body)
  • Are receiving magnetic resonance imaging or cardioversion
  • Have any sleeping disorders
  • Are pregnant or are planning to become pregnant

You should always check with your doctor or pharmacist before taking any medication, including Neupro, to ensure it is safe for you.

How much does Neupro cost?

Neupro prices will vary depending on where you buy it and how much you buy. As a guide, Neupro extended-release (1 mg/24 hr) transdermal film usually costs $750 for 30 films.

How to avoid Neupro side effects

The best way to avoid side effects is to take Neupro as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Neupro recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Neupro. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Neupro, as it can increase your risk of drowsiness.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Neupro.

7. Know the signs and symptoms of Neupro side effects

Signs and symptoms of side effects include drowsiness and problems with sleep. If you experience these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Neupro may cause fluid retention and weight gain. If you experience this side effect while taking Neupro, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Neupro.

10. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Neupro as needed.

Olumiant side effects and how to avoid them

Olumiant is an FDA (Food and Drug Administration) approved brand-name medication manufactured by Eli Lilly and Company. It is classified as a Janus kinase inhibitor used to treat rheumatoid arthritis. While Olumiant is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Olumiant include nausea. Less common but more serious side effects can include an increase in the risk of infections.

Learn more about the side effects of Olumiant and what you can do to avoid them.

What is Olumiant (baricitinib)?

Olumiant contains the prescription medicine baricitinib. Olumiant is used to reduce the symptoms of severe rheumatoid arthritis, such as pain, stiffness, and joint swelling. It helps to reduce joint and bone damage from getting worse. Olumiant may also be used for the treatment of severe alopecia areata in adults. Olumiant is used where other medication has been tried and failed, or you can not tolerate the side effects of the other medication. Using Olumiant in combination with other JAK inhibitors, biological disease-modifying antirheumatic drugs (DMARDs), or immunosuppressants such as azathioprine and cyclosporine is not advised.

Baricitinib blocks the action of Janus kinase (JAK). JAKs are enzymes in cells that help to transmit signals that influence the formation of the components of blood cells and their function as immune cells. The signals originate on the cell membrane surface due to interactions between cytokine and growth-factor receptors. Within this signaling system, JAKs normally chemically activate STATs (signal transducers and activators of transcription), which control the activity of the cells. Baricitinib prevents JAKs from activating the STATs. The actual importance of this blocking of the JAK enzyme’s action in relation to baricitinib’s medicinal action is not fully understood.

Baricitinib affects your immune system, and you may be more prone to getting infections. Your doctor may want to check you do not have any infections, such as tuberculosis, before starting your treatment.

Olumiant dosage

Olumiant is available in tablet form in the following doses: 1 mg, 2 mg, and 4 mg.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How quickly does Olumiant work?

Olumiant may show improvements in symptoms within 7 days but may take up to 12 weeks.

Olumiant side effects

The most common possible side effects of Olumiant include:

  • Nausea
  • Symptoms of a cold – stuffy nose, sneezing, sore throat, cold sores

In rare instances, Olumiant can cause more serious side effects. These can include:

  • Serious infections (due to a reduced white blood cell count) such as tuberculosis, shingles (herpes zoster), and other bacterial, viral, or fungal infections
  • Anemia (low red blood cell count)
  • Increased cholesterol levels
  • Serious life-threatening allergic reactions such as hives, trouble breathing; swelling of your face, lips, tongue, or throat
  • Increased risk of lymphoma and other cancers, including skin cancers
  • Fevers, chills, sweating
  • Muscle pains, tiredness
  • Skin sores
  • Diarrhea, stomach pain, weight loss
  • Urinary tract infection – increased urination, pain or burning when urinating
  • Shortness of breath, coughing up pink or red mucus
  • Symptoms of a blood clot in the lungs (pulmonary embolism) – chest pain, coughing up blood, wheezing
  • Symptoms of a blood clot in your leg (deep vein thrombosis) – swelling or redness in the arm or leg
  • Sign of tear in stomach or intestines (gastrointestinal perforation) – change in bowel habits, ongoing stomach pain

If you experience any of these serious side effects, stop taking Olumiant and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does baricitinib affect the liver?

Baricitinib may increase liver enzymes and can be a sign of liver damage. Those already having liver problems, such as hepatitis B may be at an increased risk of this side effect.

Does Olumiant cause weight gain?

Weight gain is not a side effect caused by Olumiant.

Does Olumiant cause high cholesterol?

Yes, Oluminant may cause an increase in triglycerides, LDL cholesterol, and HDL cholesterol.

Is Olumiant a hazardous drug?

Olumiant tablets are not known to be hazardous. Tablets that are crushed to powder are also not known to be hazardous.

Olumiant drug interactions

Olumiant can interact with other medications, including:

  • Treatment of auto-immune diseases such as rheumatoid arthritis, Crohn’s disease, ulcerative colitis – abatacept, belatacept, etanercept
  • Corticosteroids – betamethasone, cortisone, fludrocortisone, prednisolone
  • Treatment for mood disorders such as schizophrenia – clozapine
  • Immunosuppressants – cyclosporine, voclosporin
  • Treatment for multiple sclerosis – fingolimod, ozanimod, siponimod
  • Vaccines – BCG, measles, mumps, influenza, smallpox, typhoid, yellow fever, zoster
  • DMARDs (disease-modifying antirheumatic drugs) for rheumatoid arthritis – leflunomide, teriflunomide
  • Treatments for cancer – nilotinib, ribociclib
  • Strong OAT3 inhibitors (such as probenecid)

Before taking Olumiant, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Olumiant warnings & precautions

You should not use Olumiant if you:

  • Are allergic to the active ingredient baricitinib
  • Are allergic to any of the other ingredients in Olumiant
  • Have any kind of infection
  • Are breastfeeding or are planning to breastfeed – It is not known if Olumiant passes into breast milk

Talk to your doctor before using Olumiant if you:

  • Are taking any of the medications that could interact with Olumiant
  • Have or have had a chronic infection
  • Are pregnant or are planning to become pregnant
  • Have recently received or plan to receive a live vaccine
  • Have liver or kidney disease
  • Have hepatitis B or C
  • Have any stomach or intestinal problems such as diverticulitis or an ulcer
  • Have a tear or hole in your stomach or intestines
  • Have a blood clot
  • Have cancer
  • Have low white or red blood cell counts
  • Are scheduled to receive any vaccine

You should always check with your doctor or pharmacist before taking any medication, including Olumiant, to make sure it is safe for you.

How to avoid Olumiant side effects

The best way to avoid side effects is to take Olumiant as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Olumiant recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Olumiant. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid alcohol consumption to less than 14 units a week to reduce the risk of liver damage.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Olumiant.

7. Know the signs and symptoms of Olumiant side effects

Signs and symptoms of side effects include flu-like symptoms. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Olumiant.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Olumiant as needed.

Tresiba side effects and how to avoid them

Tresiba is an FDA-approved brand-name medication manufactured by Novo Nordisk Pharmaceuticals, Inc. It is classified as a long-acting insulin used to help manage blood sugar levels in patients with diabetes. While Tresiba is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Tresiba include injection site reactions. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Tresiba and what you can do to avoid them.

What is Tresiba (insulin degludec)?

Tresiba contains insulin degludec, a once-daily, long-acting type of insulin indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus. It helps lower high blood sugar by maintaining balanced blood glucose levels. Tresiba may be prescribed to patients with Type 1 diabetes or Type 2 diabetes, but it is not recommended for patients with diabetic ketoacidosis.

Tresiba dosage

Tresiba is available as a 3 mL single-use FlexTouch prefilled pen, 10 mL multiple dose vials, and 3 mL single-use Tresiba FlexTouch prefilled pens.

Inject Tresiba under your skin (subcutaneous) in your upper arm, abdomen, or thigh. Rotate injection sites to reduce the risk of lipodystrophy. Administer subcutaneously once daily at any time of day. Your insulin dose may need to change because of a change in the level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness. If you miss a dose, use the missed dose as soon as you remember. Then continue your regular dosing schedule, allowing at least 8 hours to pass between doses. Do not use two doses at one time.

Refrigerate unopened Tresiba and use until the expiration date, or store at room temperature and use within 8 weeks. Refrigerate or store opened Tresiba at room temperature and use within 8 weeks.

Please read the full prescribing information for the complete drug information, and always speak with your healthcare provider for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Is it better to take Tresiba in the morning or at night?

Adults may use Tresiba at any time of the day. Children should be given Tresiba at the same time every day.

Tresiba side effects

The most common possible side effects of Tresiba include:

  • Hypoglycemia
  • Allergic reactions
  • Injection site reactions
  • Lipodystrophy
  • Pruritus, rash, edema, and weight gain

More serious long-term side effects of Tresiba include

  • Hyperglycemia (high blood sugar), or hypoglycemia (low blood sugar levels)
  • Serious allergic reactions – trouble breathing, fast heartbeat, swelling of your face, lips, tongue, or throat
  • Severe hypoglycemia that may be life-threatening
  • Severe life-threatening hypersensitivity reactions
  • Hypokalemia (low potassium levels) – leg cramps, irregular heartbeats, increased thirst or urination, tiredness, muscle weakness, shakiness, or limp feeling
  • Fluid retention and heart failure with concomitant use of thiazolidinediones

If you experience any of these serious side effects, stop taking Tresiba and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Tresiba cause hair loss?

Hair loss is not a side effect of Tresiba. Speak to your doctor if you experience hair loss while using Tresiba.

Does Tresiba cause weight gain?

Yes. Tresiba can cause weight gain. Weight loss is not a side effect of Tresiba. Speak to your doctor for medical advice if you lose weight while taking Tresiba.

Does Tresiba cause anxiety?

Tresiba may cause hypoglycemia, a symptom of which can be anxiety. Speak to your doctor if you experience this side effect.

Does Tresiba cause heart failure?

Tresiba can cause heart failure if taken with thiazolidinediones (such as pioglitazone and rosiglitazone). Speak to your healthcare provider for medical advice if you are using both treatments.

Does Tresiba affect your kidneys?

Tresiba may cause hypoglycemia (low blood sugar levels), the risk of which is increased if you have kidney problems. Your doctor may need to change your dose if you have either of these problems.

Does Tresiba cause stomach pain?

Stomach pain is not a side effect of using Tresiba.

Tresiba drug interactions

Tresiba can interact with other medications, including:

  • Drugs that affect glucose metabolism
  • Anti-adrenergic drugs such as  beta-blockers, clonidine, guanethidine, and reserpine
  • Other diabetes medications

Before taking Tresiba, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Tresiba warnings & precautions

You should not use Tresiba if you:

  • Are allergic to the active ingredient insulin degludec
  • Are allergic to any of the other ingredients in Tresiba
  • Are having an episode of hypoglycemia
  • Drink alcohol or use prescription or over-the-counter medicines that contain alcohol

Talk to your doctor before using Tresiba if you:

  • Are taking any of the medications that could interact with Tresiba
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Tresiba, to make sure it is safe for you.

Tresiba vs Lantus

Tresiba and Lantus are both long-acting insulins available in similar forms with similar side effects. The only real difference is in how long they work in the body. Tresiba will work for up to 42 hours, while Lantus will work for up to 24 hours.

How to avoid Tresiba side effects

The best way to avoid side effects is to take Tresiba as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Tresiba that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Tresiba. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Tresiba as it can increase your risk of hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Tresiba.

7. Know the signs and symptoms of Tresiba side effects

Signs and symptoms of side effects include hypoglycemia, allergic reactions, and weight gain. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Tresiba.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Tresiba as needed.

Toujeo side effects and how to avoid them

Toujeo Solostar is an FDA-approved brand-name medication manufactured by Sanofi-Aventis. It is classified as a long-acting type of insulin used to reduce high blood sugar levels in adults and pediatric patients 6 years of age and older with diabetes mellitus. While Toujeo is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Toujeo include injection site reactions. Less common but more serious side effects can include allergic reactions.

Learn more about the side effects of Toujeo and what you can do to avoid them.

What is Toujeo (insulin glargine)?

Toujeo SoloStar (insulin glargine) is a long-acting insulin used along with diet and exercise to help treat hyperglycemia (high blood glucose levels) in adults with both type 1 and type 2 diabetes mellitus (T2DM) and type 1 diabetes mellitus (T1DM) in children 6 years of age and older. Toujeo SoloStar is not approved to treat diabetic ketoacidosis.

Toujeo SoloStar (insulin glargine) is a biological medication similar to naturally made (endogenous) insulin. The main activity of insulin, including Toujeo, is to regulate glucose metabolism. It does this by stimulating the uptake of glucose into skeletal muscle and adipose tissue (fat). Toujeo SoloStar also prevents glucose production in your liver.

More information on what is Toujeo

Toujeo dosage

Toujeo is available as 300 units of insulin glargine per milliliter in 1.5 mL Toujeo SoloStar prefilled insulin pens and 3 mL Toujeo Max SoloStar prefilled pens.

  • Toujeo SoloStar is typically given as an injection under the skin (subcutaneous) of your thighs, upper arms, or stomach area once daily. It can be given at any time of the day but should be given at the same time every day. Do not reuse needles. Use a new needle with each Toujeo SoloStar injection. Reusing needles can lead to a serious infection or cause you to get the wrong insulin dose.
  • Dispose of your used pen needles in a sharps container or a hard plastic container with a secure lid. Do not throw used needles away in your household trash.
  • Rotate your injection site with each dose of Toujeo SoloStar. You can use the same area of the body but not the same spot.
  • You should not use Toujeo SoloStar in an insulin pump or inject Toujeo SoloStar intravenously (in your vein). Do not mix Toujeo SoloStar with other insulin products.
  • You can use your Toujeo SoloStar pen for up to 56 days after its first use. New Toujeo pens can be stored in the refrigerator between 36°F and 46°F (2°C and 8°C) until their expiration date. Do not freeze Toujeo SoloStar or use it if it has been frozen. After the first time you use your Toujeo SoloStar pen, you can keep it at room temperature up to 86°F (30°C) away from direct heat and light. Do not put your pen back in the refrigerator after it has been out. Your new or used Toujeo SoloStar pen should be stored with the pen cap on.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What is the best time to take Toujeo?

Toujeo may be used at any time of the day or night but at the same time every day.

How much Toujeo is too much?

There is no maximum recommended dosage for Toujeo. But the maximum dose per injection is 80 units of insulin.

Is Toujeo a good insulin?

Toujeo offers consistent blood sugar levels, which reduces the risk of low blood sugar. Those using Toujeo are 60 % less likely to have severe hypoglycemia than those using Lantus.

Toujeo side effects

The most common possible side effects of Toujeo include:

  • Low blood sugar (hypoglycemia)
  • Injection site reactions
  • Pruritis (itching)
  • Skin rash
  • Weight gain
  • Painful or difficult urination
  • Edema
  • Lipodystrophy (pitted or thickened skin)

Toujeo can cause more serious side effects, including:

  • The risk of life-threatening severe hypoglycemia is increased with changes to your daily dose of insulin, diet, or amount of physical activity. You are also at an increased risk if you add additional diabetic medications such as short-acting insulins. Make sure you are familiar with the symptoms of hypoglycemia, which include tremors, nervousness, fast heartbeat, sweating, blurred vision, confusion, drowsiness, and extreme hunger.
  • Increased risk of low potassium levels (hypokalemia)
  • Increased risk of fluid retention and heart failure when this medication is used along with thiazolidinediones (TZDs) such as Actos (pioglitazone)
  • Serious allergic reactions, including hives, angioedema, trouble breathing, and shortness of breath

If you experience any of these serious side effects, stop taking Toujeo and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Toujeo cause weight loss or weight gain?

Toujeo may cause weight gain, a common side effect of Toujeo.

Can Toujeo cause heart failure?

Toujeo can cause heart failure if taken with thiazolidinediones (TZDs). Speak to your healthcare provider for medical advice if you are using both treatments.

Does Toujeo cause joint pain?

No, joint pain is not a side effect of Toujeo.

Can Toujeo cause a yeast infection?

No. Yeast infections are not a known side effect of Toujeo.

Toujeo drug interactions

When Toujeo SoloStar is taken with other medications, it can change the way they work or increase the frequency and severity of side effects. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take, including:

  • Other diabetic medications, such as metformin
  • Beta-blockers
  • Diuretics
  • Corticosteroids
  • Atypical antipsychotics

Toujeo contraindications

Don’t take Toujeo if:

  • Hypersensitivity to Toujeo SoloStar or any of its inactive ingredients.
  • Are having an active episode of hypoglycemia (low blood sugar level) or diabetic ketoacidosis.

Talk to your doctor before taking Toujeo if you:

  • Have liver or kidney problems
  • Heart failure or other heart problems
  • Are taking thiazolidinediones (TZDs)
  • Are pregnant, plan on becoming pregnant, or are breastfeeding

You should always check with your doctor or pharmacist before taking any medication, including Toujeo, to make sure it is safe for you.

How to avoid Toujeo side effects

The best way to avoid side effects is to take Toujeo as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Toujeo recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Toujeo. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Toujeo, as it can increase your risk of hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Toujeo.

7. Know the signs and symptoms of Toujeo side effects

Signs and symptoms of side effects include hypoglycemia. If you experience any of the symptoms of hypoglycemia, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Toujeo.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Toujeo as needed.

Spiriva side effects and how to avoid them

Spiriva is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Boehringer Ingelheim Pharmaceuticals, Inc. It is classified as a long-acting muscarinic antagonist (LAMA) and is used to treat chronic obstructive pulmonary disease (COPD). While Spiriva is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Spiriva include upper respiratory tract infections. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Spiriva and what you can do to avoid them.

What is Spiriva (tiotropium)?

Spiriva is an anticholinergic bronchodilator indicated for:

  • The long-term, once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD) and for reducing COPD exacerbations. (COPD includes chronic bronchitis and emphysema)
  • The long-term, once-daily, maintenance treatment of asthma in patients 12 years of age and older. Spiriva Respimat is indicated for the relief of acute bronchospasm.

Spiriva dosage

Spiriva is available in capsule form containing 18 mcg of tiotropium powder for oral inhalation using a Handihaler device. Do not swallow the Spiriva capsules. Use two inhalations of the tiotropium powder once daily.

Spiriva is also available as Spiriva Respimat in an inhalation spray form in doses of 1.25 mcg or 2.5 mcg tiotropium per actuation.

Spiriva Respimat or Spiriva Handihaler devices are not rescue medicines and should not be used for treating sudden breathing problems or for sudden asthma symptoms.

Please read the prescribing information and the medication guide for the complete drug information. Always speak with a healthcare professional for medical advice or any changes to your dose so they can monitor and evaluate your condition. Store this medicine at room temperature away from moisture and heat, and do not freeze.

Spiriva side effects

The most common possible side effects of Spiriva include:

  • Pharyngitis
  • Bronchitis
  • Headache
  • Upper respiratory tract infection, dry mouth, sinus infection, sinusitis, cough, sore throat
  • Non-specific chest pain
  • Urinary tract infection, painful urination
  • Indigestion
  • Constipation
  • Increased heart rate

In rare instances, Spiriva can cause more serious long-term side effects. These can include:

  • Immediate hypersensitivity reactions – angioedema, hives, bronchospasm, or anaphylaxis
  • Paradoxical bronchospasm which may be life-threatening – coughing, difficulty breathing, shortness of breath
  • Worsening of narrow-angle glaucoma
  • Blurred vision, eye pain or redness, seeing halos around lights
  • Worsening of urinary retention
  • Eye pain, swelling, redness, vision changes, blurred vision

If you experience any of these serious side effects, stop taking Spiriva and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Spiriva cause anxiety?

Anxiety is not a side effect associated with using Spiriva. Speak to your doctor for medical advice if you experience this side effect.

Does Spiriva cause weight gain?

Weight gain is not a side effect of using Spiriva to treat asthma or COPD. Speak to your doctor if you have concerns while using Spiriva.

Does Spiriva cause coughing?

Yes. Common side effects of Spiriva include sore throat, dry mouth, coughing, and sinus infection.

Spiriva drug interactions

Spiriva can interact with other medications, including:

  • Anticholinergics
  • Bronchodilators
  • Treatments for depression, anxiety, mood disorders, or mental illness
  • Treatments for Parkinson’s disease
  • Treatments for stomach problems, motion sickness, or irritable bowel syndrome
  • Treatments for an overactive bladder

Before taking Spiriva, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Spiriva contraindications

Don’t take Spiriva if:

  • Are allergic to the active ingredient tiotropium bromide, ipratropium, or atropine
  • Have had an allergic reaction to any of the other ingredients in Spiriva
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Spiriva if you:

  • Have an allergy to milk proteins
  • Are taking any of the medications that could interact with Spiriva
  • Have moderate to severe renal impairment
  • Have narrow-angle glaucoma
  • Have a milk allergy
  • Have an enlarged prostate or urination problems
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Spiriva, to make sure it is safe for you.

How to avoid Spiriva side effects

The best way to avoid side effects is to take Spiriva as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Spiriva that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Spiriva. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your healthcare provider if you experience any problems with your feet while taking Spiriva.

6. Know the signs and symptoms of Spiriva side effects

Signs and symptoms of side effects include upper respiratory tract infections and thrush. If you experience these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Spiriva.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Spiriva as needed.

Taltz side effects and how to avoid them

Taltz is a brand-name medication manufactured by Eli Lilly and Company. It is classified as a monoclonal antibody used to treat certain autoimmune diseases such as psoriasis. While Taltz is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Taltz include injection site reactions. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Taltz and what you can do to avoid them.

What is Taltz (ixekizumab)?

Taltz is a medication prescribed to adults and children to help treat the following autoimmune diseases:

  • Active psoriatic arthritis in adults (Taltz can be used alone or with another medicine called methotrexate)
  • Moderate-to-severe plaque psoriasis in adults and children over six years old who are candidates for systemic therapy or phototherapy
  • Active ankylosing spondylitis in adults
  • Active non-radiographic axial spondyloarthritis with signs of inflammation in adults

Unfortunately, there are no permanent cures for the above autoimmune diseases. They can, however, be managed with medications that help reduce their symptoms, like Taltz. Taltz helps to reduce the amount of inflammation your immune system causes. This can ease the symptoms of your disease.

The active ingredient in Taltz is called ixekizumab. It helps to reduce the amount of inflammation your immune system triggers. Ixekizumab works by blocking the action of a substance in your body called interleukin. This substance is produced by your immune system to trigger inflammation. Ixekizumab binds with interleukin, stopping it from working, and reducing how much inflammation your immune system can cause.

Taltz dosage

Taltz is available in injection form as an 80 mg/mL solution in a single-dose prefilled autoinjector or prefilled syringe.

You inject Taltz under your skin (subcutaneous injection), usually in your thighs, stomach, or the back of your arm. It comes in an autoinjector and a prefilled syringe that you can inject yourself, or it can be injected by a caregiver in your home.

You are advised to read the medication guide and prescribing information provided with this medicine for the drug information and patient information and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How long do you stay on Taltz?

You will continue using Taltz for as long as your doctor recommends you to do so.

Can you drink alcohol while on Taltz?

Alcohol does not interact with Taltz but may cause a flare-up of conditions such as ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis.

Taltz side effects

The most common possible side effects of Taltz include:

  • Injection site reactions, like itching, bruising, rashes, and pain
  • Nausea, stomach pain
  • An increased risk of upper respiratory tract infections
  • Flu-like symptoms such as stuffy nose, sneezing, sore throat
  • An increased risk of fungal infections

Sometimes Taltz can cause long-term, more serious side effects. These are rarer but could include:

  • An increased risk of developing a serious infection, like tuberculosis or thrush, as Taltz can reduce your immune system’s ability to fight infections
  • Serious allergic reactions such as hives, skin rash, swelling of the face, tongue, or throat, severe dizziness, chest tightness, trouble breathing
  • A risk of developing an inflammatory bowel disease like Crohn’s disease or ulcerative colitis, or a risk of these diseases getting worse if you already have them

If you experience any of these serious side effects, stop taking Taltz and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Taltz cause weight loss or weight gain?

Taltz is not known to cause changes in weight. Serious infections and inflammatory bowel disease may, however cause weight loss.

Does Taltz cause hair loss?

Hair loss is not a side effect of using Taltz treatment. However, plaque psoriasis affecting your scalp can cause hair loss.

Does Taltz affect the eyes?

Taltz can cause conjunctivitis as a rare side effect. It is important to be aware that children using Taltz for the treatment of plaque psoriasis experience conjunctivitis more than adults.

Does Taltz cause depression?

Depression is not a side effect of Taltz but is common in those suffering from psoriasis or psoriatic arthritis.

Does Taltz cause fatigue?

Fatigue is not a common side effect of using Taltz. If you experience this symptom, speak to your doctor for medical advice.

How long do Taltz side effects last?

Mild side effects of Taltz may go away in a few days to a couple of weeks but speak to your doctor if side effects become troublesome.

Why does Taltz hurt so bad?

Taltz may cause injection site reactions such as redness or pain.

Taltz drug interactions

Taltz can interact with other medications, including:

  • Any other medications you’re taking for your condition
  • Any medications that affect the way your liver enzymes work
  • Any antibiotics or other medications you’re taking to treat a bacterial infection
  • Any medications you’re taking to treat a fungal infection
  • Live vaccines

Before taking Taltz, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Taltz warnings & precautions

Don’t take Taltz if you:

  • Are allergic to the active ingredient ixekizumab
  • Are allergic to any of the other ingredients in Taltz
  • Are under 18 years of age to treat psoriatic arthritis, ankylosing spondylitis, or non-radiographic axial spondyloarthritis

Talk to your doctor before taking Taltz if you:

  • Have tuberculosis or have recently been in contact with someone with tuberculosis
  • Are currently being treated for an infection or have an infection
  • Have Crohn’s disease or ulcerative colitis
  • Have recently had a vaccine, or are due to have a vaccine
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding – It is not known if ixekizumab passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Taltz, to make sure it is safe for you.

How to avoid Taltz side effects

The best way to avoid side effects is to take Taltz as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Taltz that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Taltz. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Taltz.

6. Know the signs and symptoms of Taltz side effects

Signs and symptoms of side effects include upper respiratory tract infections. If you experience any of these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Taltz.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Taltz as needed.

Savella side effects and how to avoid them

Savella is an FDA-approved brand-name medication manufactured by Forest Pharmaceuticals, Inc. It is classified as a serotonin–norepinephrine reuptake inhibitor (SNRI) and is used for the treatment of fibromyalgia. While Savella is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Savella include an increased heart rate. Less common but more serious side effects can include suicidal thoughts and behavior.

Learn more about the side effects of Savella and what you can do to avoid them.

What is Savella?

Savella is a medication prescribed to adults to help them manage the symptoms of a pain condition called fibromyalgia. Fibromyalgia is a condition where you feel widespread pain across your body and/or feel more sensitive to pain and pressure. You may also experience numbness, tingling, muscle spasms, and increased sensitivity to light, temperature, and noise.

Although there’s no cure for fibromyalgia, you can manage your condition with medications like Savella. You take Savella as a tablet that should be swallowed with water. It can help to reduce the pain you feel, which can then lead to an improvement of your other symptoms which are related to the pain.

The active ingredient in Savella is called milnacipran. It’s a type of drug known as a serotonin–norepinephrine reuptake inhibitor (SNRI). These drugs are usually used to treat depression, but Savella isn’t an antidepressant. It has a similar action to SNRI antidepressants, as it alters your brain chemistry, but in Savella’s case, this has been shown to help treat fibromyalgia.

Milnacipran works by increasing the levels of two natural chemicals (neurotransmitters) in your brain called serotonin and norepinephrine. Your brain produces these chemicals, and they help regulate your brain activity by allowing signals to pass through your brain cells.

Serotonin and norepinephrine are continually produced and broken down in your brain. But milnacipran slows how quickly they’re broken down, causing their levels to rise. This increase in serotonin and norepinephrine levels has been shown to reduce fibromyalgia pain.

Does Savella give you energy?

As well as relieving fibromyalgia pain, Savella helps reduce fatigue, a common symptom in people suffering from fibromyalgia.

Does Savella help with depression and anxiety?

Savella is not for the treatment of depression but works like other medicines used to treat depression and other psychiatric disorders.

Savella dosage

Savella is available in tablet form in the following doses: 12.5 mg, 25 mg, 50 mg, and 100 mg.

Read the medication guide and prescribing information provided with this medicine for the complete drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What time of day is best to take Savella?

Take Savella early each day at 2 a.m. and 5 a.m. with food.

Savella side effects

The most common side effects caused by Savella in clinical trials compared to placebo include:

  • Headaches
  • Dizziness
  • Drowsiness
  • A dry mouth
  • Constipation
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Trouble sleeping (insomnia)
  • Hot flushes
  • Increased sweating
  • Heart palpitations
  • An increased heart rate
  • High blood pressure (hypertension)

In rare instances, Savella can cause long-term serious side effects, including:

  • Worsening of suicidal thoughts and suicide, particularly in young adults
  • Manic episodes – these cause an increase in energy, racing thoughts, rapid speech, and impulsive behavior
  • Severe allergic reactions to the medication
  • Serotonin syndrome – a potentially life-threatening condition caused by high levels of serotonin
  • A dangerous increase in blood pressure
  • A dangerous increase in heart rate
  • Liver problems that can reduce your liver function
  • Seizures (convulsions)
  • Difficulties urinating and difficulties ejaculating in men
  • Problems with your vision, including eye pain and changes in your vision
  • Low blood salt levels, particularly in elderly patients
  • An increased risk of bleeding, particularly if taken with drugs that stop your blood clotting. These include warfarin (Coumadin or Jantoven), nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, or aspirin

You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Savella cause fibromyalgia?

No, Savella is prescribed to help you manage fibromyalgia.

Does Savella cause weight loss or weight gain?

Savella does not cause weight gain or weight loss.

How long do Savella’s side effects last?

Savella has a half-life of around 8 hours and takes several weeks to be eliminated from your body. Side effects may last until this happens.

Does Savella cause withdrawal symptoms?

Suddenly stopping treatment with Savella may cause withdrawal symptoms such as mood swings, tiredness, and changes in sleep. Talk to your doctor about stopping treatment with Savella.

Savella drug interactions

Savella can interact with other medications, including:

  • Monoamine oxidase inhibitor (MAOI) antidepressants – linezolid, metaxalone, methylene blue, phenelzine, rasagiline, and selegiline
  • Any other antidepressants, like tricyclic antidepressants, SSRIs, other SNRIs, or lithium
  • Any other medications that can affect your serotonin or norepinephrine levels
  • Any other medications are taken to treat mental states and conditions, like mood and thought disorders, anxiety, or psychotic disorders
  • Any medications that can reduce blood clotting, like warfarin (Coumadin or Jantoven), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
  • Opioid pain medications, like fentanyl or tramadol
  • Blood thinners
  • An herbal supplement called St. John’s Wort

Before taking Savella, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Savella warnings & precautions

Savella isn’t suitable for everyone. Don’t take Savella if you:

  • Are allergic to the active ingredient milnacipran, or any of the other ingredients in Savella
  • Are taking a Monoamine Oxidase Inhibitor (MAOI). You shouldn’t take Savella if you’ve taken an MAOI in the last 14 days, and avoid taking an MAOI for five days after you last take Savella
  • Are under 18 years of age

Talk to your doctor before taking Savella if you:

  • Are taking any of the medications that could interact with Savella
  • Have, or have had, depression, suicidal thoughts, or have ever tried to commit suicide
  • Have, or have any family history, of mania or bipolar disorder
  • Have ever had seizures (convulsions)
  • Have any heart problems
  • Have high blood pressure
  • Have any kidney problems
  • Have liver disease
  • Have a personal or family history of glaucoma
  • Have low blood sodium levels
  • Have, or have had, any bleeding problems
  • Drink alcohol
  • Are pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Savella, to make sure it is safe for you.

How to avoid Savella side effects

The best way to avoid side effects is to take Savella as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Savella that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Savella. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Savella as it can increase your risk of side effects such as drowsiness, suicidal thoughts, and liver problems.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Savella.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Savella.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Savella as needed.

Rytary side effects and how to avoid them

Rytary is an FDA (Food and Drug Administration) approved brand-name medication manufactured by Amneal Pharmaceuticals used to treat Parkinson’s disease. While Rytary is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Rytary include muscle stiffness. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Rytary and what you can do to avoid them.

What is Rytary used for?

Rytary is a prescription medication used to treat the symptoms of:

  • Parkinson’s disease
  • Parkinsonism caused by carbon monoxide or manganese poisoning
  • Parkinsonism caused by viral infections of your brain (post-encephalitic parkinsonism)

Parkinson’s disease is a long-term degenerative condition that affects your brain and is caused by the death and loss of brain cells. It’s thought that cells are killed by a build-up of harmful proteins in your brain. Cells are usually lost in an area of your brain called your substantia nigra that produces a chemical called dopamine. This loss of dopamine makes it harder for your brain to coordinate your body movements.

The symptoms of Parkinson’s disease usually come on slowly. The first signs are typically movement problems, like moving slowly, rigid muscles, and shaking. Over time these problems can become more pronounced and lead to tremors, difficulties walking, and problems with speech. Other symptoms of Parkinson’s disease include problems with thinking, mood swings, anger, and emotional outbursts. Depression, anxiety, and other mental health issues are common. As the disease progresses, it often causes dementia – severe thinking and memory problems.

Parkinsonism is the name for the group of movement symptoms of Parkinson’s disease causes. As well as being brought on by Parkinson’s disease, they can be caused by exposure to toxins like manganese or carbon monoxide. Parkinsonism can also be caused by viral infections that produce swelling that damages the substantia nigra (post-encephalitic parkinsonism).

What does Rytary do for Parkinson’s?

Parkinson’s disease can’t be cured, but you can manage the movement symptoms of Parkinson’s and parkinsonism with medications like Rytary. You take Rytary as a capsule that you swallow. It helps to increase levels of dopamine in your brain, relieving or slowing the worsening of movement symptoms.

Rytary has two active ingredients called carbidopa-levodopa. They both help to increase levels of dopamine in your brain. Levodopa is an amino acid, but once it’s taken into your body, it’s converted in your brain cells into dopamine. Carbidopa is a type of medicine called an ‘amino acid decarboxylase inhibitor. This means it’s a drug that slows down how fast amino acids, like levodopa, are broken down in your body. This allows more levodopa to make it through your blood-brain barrier, increasing the amount of dopamine. You can think of levodopa as the ingredient that has the initial effect (increasing dopamine), and carbidopa is the ingredient that boosts the effect of levodopa.

Rytary dosage

Rytary is available as extended-release capsules of carbidopa and levodopa in doses of 23.75 mg/95 mg, 36.25 mg/145 mg, 48.75 mg/195 mg, and 61.25 mg/245 mg.

Take your first dose of the day around 1 to 2 hours before food. Swallow Rytary capsules whole three times a day. If you are unable to swallow the capsules, open them and sprinkle the contents onto a small amount of applesauce. Swallow the mixture right away.

Avoid taking Rytary with a high-fat meal, as this can slow down how quickly it works. Do not take Rytary with iron supplements or multivitamins with minerals containing iron, as this can reduce the amount of carbidopa/levodopa absorbed by your body.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How much is too much Rytary?

The maximum recommended daily dose of Rytary is 612.5 mg/2450 mg.

Rytary side effects

The most common possible side effects of Rytary include:

  • Headaches
  • Dizziness
  • Drowsiness
  • A dry mouth
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Constipation
  • Problems falling asleep (insomnia)
  • Abnormal dreams
  • Muscle stiffness
  • Difficulties with voluntary movements (dyskinesia)
  • Anxiety
  • Falls in blood pressure after standing up (orthostatic hypotension)

In rare instances, Rytary can cause more serious side effects, including:

  • Severe allergic reactions including rash, itching, swelling of the face, tongue, or throat, severe dizziness, trouble breathing
  • Daytime sleepiness
  • Falling asleep during daily activities
  • Reduced blood flow to your heart (cardiovascular ischemic events)
  • An increased risk of developing peptic ulcers (ulcers in your digestive system)
  • An increased risk of developing the eye problem glaucoma
  • An increased risk of developing a type of skin cancer called melanoma
  • Hallucinations and periods of psychosis (a loss of connection with reality)
  • An increase in compulsive behaviors
  • Confusion and worsening of symptoms caused by reducing your dose or when you stop taking Rytary

If you experience any of these serious side effects, stop taking Rytary and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Rytary?

Long-term serious side effects of Rytary include anxiety, extreme sleepiness, dyskinesia, and psychosis.

Does Rytary cause weight loss?

Weight loss is not a side effect reported with the use of Rytary. Rytary may cause problems with your digestion, leading to a loss of appetite and weight loss.

Does Rytary cause anxiety?

Anxiety is a side effect of using Rytary. Speak to your doctor if you experience this side effect.

Does Rytary cause hallucinations?

Rytary commonly causes low blood pressure which can result in dizziness, lightheadedness, and hallucinations.

Rytary drug interactions

Rytary can interact with other medications including:

  • Nonselective monoamine oxidase inhibitors (MAO inhibitors) such as rasagiline, safinamide, and selegiline, usually taken as antidepressants (may cause high blood pressure)
  • Any other medications taken for mental health problems
  • Any other medications for Parkinson’s disease
  • Any other medications that contain levodopa
  • Medications used to treat any movement disorders
  • Medications taken to treat low iron
  • Phenytoin used to treat fits (convulsions)
  • Isoniazid a antituberculosis agent
  • Metoclopramide a prokinetic agent
  • Anticholinergic medicines; like orphenadrine, trihexyphenidyl, benztropine, or procyclidine

Before taking Rytary, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Rytary warnings & precautions

Don’t take Rytary if you:

  • Are allergic to the active ingredients levodopa and carbidopa
  • Are allergic to any of the other ingredients in Rytary
  • Are taking, or have recently taken, a type of medication called a nonselective monoamine oxidase inhibitor (MAOI), like phenelzine and tranylcypromine, usually taken as an antidepressant
  • Have ever had skin cancer
  • Have ever had an eye condition called narrow-angle glaucoma
  • Are under 18 years of age

Talk to your doctor before taking Rytary if you:

  • Have blood disorders
  • Have breathing problems
  • Have glaucoma
  • Have heart or blood vessel problems such as an irregular heartbeat, heart attack, or angina
  • Have ever had any heart, liver, kidney, or hormonal problems
  • Have any mental health problems
  • Have epilepsy or have a history of fits (convulsions)
  • Have ever had a peptic ulcer
  • Have problems with sleepiness or falling asleep in the daytime
  • Are planning to have surgery
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

Rytary can cause side effects like sleepiness and dizziness that can impair your ability to drive, operate machinery, or perform other dangerous tasks.

Is Rytary better than Sinemet?

The effects of Rytary last longer than they do for Sinemet (immediate release) and Sinemet CR (controlled release). Rytary is, therefore, better at helping to control Parkinson’s symptoms.

How to avoid Rytary side effects

The best way to avoid side effects is to take Rytary as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Rytary that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Rytary. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Rytary as it can increase your risk of side effects such as sleepiness and impaired cognitive function.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Rytary.

7. Know the signs and symptoms of Rytary side effects

Signs and symptoms of side effects include sleepiness and daytime drowsiness. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Rytary.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Rytary as needed.

Repatha side effects and how to avoid them

Repatha is an FDA-approved medication manufactured by Amgen. It is classified as a PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor and is used to reduce cholesterol levels. While Repatha is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Repatha include upper respiratory tract infections. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Repatha and what you can do to avoid them.

What is Repatha (evolocumab)?

Repatha is approved to:

  • Treat adults with primary hyperlipidemia (high cholesterol), including those with heterozygous familial hypercholesterolemia (HeFH), alongside a healthy diet and may be used with other LDL-lowering treatments
  • Reduce the risk of cardiovascular problems (such as heart attack and stroke) in adults with heart disease
  • Treat adults and children aged 13 to 17 years with homozygous familial hypercholesterolemia (HoFH) with a healthy diet and other LDL-lowering treatments to lower cholesterol levels

Repatha works by blocking PCSK9, which means more receptors are available to remove LDL-C (low-density lipoprotein cholesterol) from the blood. This results in lower LDL cholesterol levels. LDL-C is sometimes described as bad cholesterol because it collects in the walls of the arteries leading to your heart. HDL (high-density lipoprotein cholesterol) is known as good cholesterol because it takes cholesterol away from the heart. Lowering LDL-C cholesterol reduces your risk of cardiovascular disease and reduction in blood cholesterol.

Repatha dosage

Repatha comes in liquid form in prefilled syringes that are given as a subcutaneous injection under the skin in your upper arm, thigh, or abdomen area.

Repatha can also be used as a SureClick autoinjector and as the Pushtronex system, which is a single-use, on-body infusor with prefilled cartridges.

You are advised to read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Repatha side effects

The most common possible side effects of Repatha compared to placebo include:

  • High blood sugar
  • Urinary tract infection (UTI)
  • Upper respiratory tract infection
  • Nasopharyngitis
  • Painful back
  • Muscle pain
  • Injection site reactions
  • Influenza (flu)
  • Hypertension (high blood pressure)

Repatha can cause more serious side effects, including:

  • Serious allergic reactions to the medication – rash, itching skin, trouble breathing or swallowing, hives, large, hive-like swelling on the face, eyelids, lips, tongue, throat
  • Diabetes – high blood sugar levels (a common but serious side effect)

If you experience any of these serious side effects, stop taking Repatha and seek medical attention immediately. You are encouraged to report the adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Repatha cause hair loss?

Hair loss is not a side effect reported by those using Repatha in clinical trials.

Does Repatha cause fatigue?

Fatigue is not a common side effect of Repatha. Fatigue caused by Repatha can be a symptom of serious side effects such as diabetes or high blood sugar levels.

Can Repatha cause heart problems?

Repatha can cause an increase in blood pressure. You will need to have your blood pressure checked when starting and during treatment with Repatha.

Does Repatha affect the liver?

Repatha does not cause liver-related side effects.

Does Repatha cause weight gain?

Weight gain is not a side effect reported in studies on Repatha.

Does Repatha cause back pain?

Repatha may cause flu or flu-like symptoms, one of which may include back pain.

Do Repatha’s side effects go away?

Mild side effects of Repatha go away within a few days or weeks. Speak to your doctor if you experience more serious side effects that last longer.

Does Repatha have the same side effects as statins?

Repatha belongs to a different class of drugs than statins. It has a different mechanism of action and will also have different side effects.

Repatha warnings & precautions

Repatha isn’t suitable for everyone. Don’t take Repatha if you:

  • Are allergic to the active ingredient evolocumab
  • Are allergic to any of the other ingredients in Repatha
  • Are under 18 years of age to treat cardiovascular disease
  • Are under 18 years of age to treat primary hyperlipidemia
  • Are under 13 years to treat homozygous familial hypercholesterolemia

Talk to your doctor before taking Repatha if you:

  • Have any liver problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are allergic to latex or rubber, as the needle cover of the prefilled syringe and the prefilled autoinjector contain rubber derived from latex

How to avoid Repatha side effects

The best way to avoid side effects is to take Repatha as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Repatha that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Repatha. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Repatha.

6. Know the signs and symptoms of Repatha side effects

Signs and symptoms of side effects include upper respiratory tract infections. If you experience these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Repatha.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Repatha as needed.

Money-Making States

It goes without saying how vital the healthcare industry is to the U.S. Despite how easy it is to buy affordable medication online, going to hospitals for check-ups and emergencies is crucial for your long-term health.

Not only is the healthcare industry important for the well-being of U.S. citizens, but it’s also a lucrative business for investors. That’s why we wanted to find out which states earn the most money through their hospitals. We’ve looked at the individual hospitals earning the most through net patient revenue, the states with the most for-profit hospitals, and the states who earn the most through their hospitals.

Hospitals Making the Most Money

We’ve looked at the net patient revenue of individual hospitals to find out which hospitals make the most money.

Hospitals making the most money

 

1. New York-Presbyterian/Weill Cornell Medical Center

$5.73bn net patient revenue

The hospital making the most money is the New York Presbyterian/Weill Cornell Medical Center, which made just over $5.73 billion from patient revenue in 2021. The Weill Cornell Medical Center is one of eight campuses that make up the New York Presbyterian. This specific campus specializes in epilepsy, Alzheimer’s disease, and stroke.

2. Tisch Hospital

$5.67bn net patient revenue

In second place is Tisch Hospital which is part of NYU Langone Health. Tisch Hospital made $5.6 billion from patient revenue in 2021 and is ranked as the best hospital in New York, and the third best in the U.S.

3. Cleveland Clinic Main Campus

$5.24b net patient revenue 

Completing our top three is Cleveland Clinic Main Campus which earned $5.24 billion in 2021. Cleveland Clinic is considered one of the best hospitals in the U.S. and was even the first hospital in America to perform a face transplant. Cleveland Clinic has also made a number of medical breakthroughs, including coronary artery bypass surgery.

States with the Highest Percentage of For-Profit Hospitals

For-profit hospitals are hospitals owned by at least one investor, and we wanted to find out which states in the U.S. have the highest percentage of these.

States with the highest percentage for-profit hospitals

 

 

1. Nevada – 54.3% of for-profit hospitals 

Nevada is the state with the most for-profit hospitals. 54.3% of the hospitals in Nevada are for-profit, compared to 32.6% which are non-profit, and just 13% which are controlled by the state or local government. 

2. Texas – 51.8% for-profit hospitals 

Texas is in second place with 51.8% of hospitals being investor-owned. Texas also has the second lowest number of non-profit hospitals at 29.3%. Only Wyoming has less at 17.9%. 18.9% of the hospitals in Texas are owned by the state or local government, which is the highest among our top three.

3. Florida – 48.1% for-profit hospitals

Completing our top three is Florida, with 48.1% of hospitals owned by investors. 29.3% of hospitals in Florida are non-profit, and just 9.8% of hospitals are owned by the state or local government which is the second lowest figure in our top ten.

States with the Most For-Profit Hospitals

We wanted to find out which states have the highest total of for-profit hospitals.

States with the most for-profit hospitals

 

1. Texas – 271 for-profit hospitals

Texas takes the top spot with 271 for-profit hospitals. Texas’ total is almost 170 more than any other state, as well as the highest total hospitals with 523. 153 non-profit hospitals and 99 state/local government hospitals make up the remaining 252 hospitals in Texas.

2. Florida – 103 for-profit hospitals

Despite having just the third-highest percentage of for-profit hospitals, Florida clinches second place with the second-highest total. 103 of Florida’s 214 hospitals are for-profit, with 90 non-profit hospitals, and 21 owned by the government/state. 

3. California – 81 for-profit hospitals

Completing our top three is California with 81 for-profit hospitals. Just 22.9% of California’s hospitals are for-profit, which ranks 18th in our previous list. The majority of California’s hospitals are actually non-profit, with a total of 205 which is the highest out of any state in the U.S.

States with the Highest Patient Revenue

We’ve looked at the gross patient revenue across all hospitals in each state to find out which state makes the most.

States with the highest potential revenue

 

1. California – $568 billion gross patient revenue 

California takes the top spot here with gross patient revenue of almost $569 billion. California’s total patient revenue is $150 billion more than any other state. California tops the list in each category, with more staffed beds, total discharges, and patient days than any other state.

2. Texas – $411 billion gross patient revenue

Texas takes second place with gross patient revenue of $411 billion. Texas also has almost 60,000 staffed beds, as well as 2.6 million discharges. Only one Texas hospital made the top 10 list of hospitals making the most money, and that was the University of Texas MD Anderson Cancer Center which had a net patient revenue of $3.6 billion.

3. Florida – $401 billion gross patient revenue

Florida completes our top three with gross patient revenue of $401 billion. Like Texas, just one hospital in Florida made the top 10 hospitals making the most money. That was AdventHealth Orlando which earned $4 billion from patient revenue. Despite having fewer staffed beds than fourth-placed New York, Florida had more patient days and discharges.

Methodology

To find out the hospitals making the most money, we used Definitive Healthcare.

We then used KFF to find out the percentage and totals of for-profit hospitals in each state.

Finally, we used American Hospital Directory to find out the states with the highest patient revenue.

Multaq side effects and how to avoid them

Multaq is an FDA-approved medication manufactured by Sanofi-Aventis. It is classified as an antiarrhythmic and is used to prevent or treat certain types of atrial fibrillation (AFib) in adults. While Multaq is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Multaq include loss of appetite and stomach pain. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Multaq and what you can do to avoid them.

What is Multaq (dronedarone)?

Multaq is an antiarrhythmic medication used to maintain a normal heart rhythm and reduce hospitalization in patients with paroxysmal or persistent atrial fibrillation (AF) or atrial flutter. This medication should not be used if you have permanent atrial fibrillation because of the increased risk of serious side effects.

Does Multaq stop AFIB?

The exact mechanism of action of Multaq is not known. It is thought to work by blocking potassium channels in your heart to help reduce its electrical activity. This helps you stay in a normal sinus rhythm and prevents you from going into AFib.

Multaq dosage

Multaq is available as 400 mg film-coated tablets. Multaq is typically taken twice daily, once with your morning meal and once with your evening meal. If you miss a dose of Multaq, skip it and take your next dose at its normal time. Do not take 2 doses at once to make up for a missed dose.

Monitor for symptoms of heart failure while on Multaq. Your doctor may pause or discontinue this medication if you have signs of severe heart failure. Your doctor should take blood tests to ensure your potassium and magnesium levels are normal while you are on Multaq. Multaq can affect your heart rhythm and cause QT prolongation. QT prolongation can sometimes cause a fast or irregular heartbeat.

You are advised to read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How long does Multaq stay in your system?

Multaq has a half-life of 13-19 hours, this is the time it takes for half of the Multaq to leave your body. It normally takes around 5 half-lives for this drug to completely leave your body.

Can you ever get off Multaq?

Yes, but you should speak to your doctor before stopping this medication. Stopping Multaq suddenly may worsen your Afib.

Is there an alternative to Multaq?

Your doctor can prescribe other medications if Multaq is not right for you. They will vary by factors such as side effects and cost. Some alternative FDA-approved treatment options include:

Multaq side effects

The most common side effects of Multaq seen in clinical trials when compared to placebo include:

  • Nausea
  • Vomiting
  • Loss of appetite
  • Weakness
  • Stomach pain
  • Bradycardia (slow heartbeat)
  • Unusual tiredness
  • Indigestion
  • Skin reactions such as rash and itching

Multaq can sometimes cause more serious side effects, including:

  • Serious, life-threatening allergic reactions (hives, swelling of the face or throat, and shortness of breath)
  • Increased risk of death, stroke, or hospitalization
  • Ventricular tachycardia
  • Lung problems such as a dry cough or shortness of breath
  • Liver injury such as abdominal pain, jaundice (yellowing of the skin or eyes), and dark urine
  • Low magnesium or potassium levels

Contact your healthcare professional for medical advice about any possible side effects you experience while taking Multaq. You can report your adverse reactions to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What are the long-term side effects of Multaq?

Long-term side effects include a slowed heartbeat, inflammation of the lungs, low potassium and magnesium levels, changes in kidney function, and life-threatening liver failure.

What are Multaq’s side effects in the elderly?

Side effects of Multaq on the elderly include a slowed heartbeat, inflammation of the lungs, low potassium and magnesium levels, changes in kidney function, and life-threatening liver failure.

Does Multaq cause hair loss?

Hair loss is a side effect of taking Multaq, especially in females over the age of 60 that have been taking Multaq for 1 to 6 months.

Does Multaq cause weight gain?

Multaq does not commonly cause weight gain. If you notice unexplained weight gain, swelling, or shortness of breath, contact your doctor immediately, as those could be symptoms of heart failure.

Multaq drug interactions

When Multaq is taken with other medications, it may change how Multaq works or increase the frequency and severity of side effects. You should ask your doctor if any of the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take may cause drug interactions with Multaq, including:

  • Antiarrhythmics such as amiodarone
  • Antifungals such as itraconazole, ketoconazole, or voriconazole
  • Antibiotics such as clarithromycin or telithromycin
  • HIV medications such as ritonavir
  • Potassium-depleting diuretics
  • Beta-blockers such as atenolol
  • Phenothiazines such as chlorpromazine
  • Tricyclic antidepressants such as amitriptyline
  • Nefazodone
  • Cyclosporine
  • St. John’s wort
  • Digoxin
  • Grapefruit juice
  • Warfarin

Multaq and Eliquis interaction

Dronedarone may increase apixaban blood levels, resulting in an increased risk of bleeding. You may need to monitor and adjust the dose of Multaq more frequently if this is the case.

Multaq contraindications

You should not use Multaq if you have an allergy to dronedarone or any inactive ingredients in this product. You should also avoid this medication if you have any of the following:

  • Heart failure
  • Atrioventricular (AV) block or sick sinus syndrome unless you have a pacemaker
  • Low heart rate
  • Using other medications or supplements that prolong the QT interval
  • Severe liver disease

Talk to your doctor before taking Multaq if you:

  • Have heart problems such as heart failure or arrhythmias
  • Have liver problems
  • Are taking medications that affect your heart rate or rhythm
  • Are pregnant, or plan on becoming pregnant. Women who are able to become pregnant should use birth control
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Multaq, to make sure it is safe for you.

How to avoid Multaq side effects

The best way to avoid side effects is to take Multaq as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Multaq as recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Multaq. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Multaq, as it can increase your risk of side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Multaq.

7. Know the signs and symptoms of Multaq side effects

Signs and symptoms of side effects include loss of appetite and stomach pains. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Multaq.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Multaq as needed.

Prolia side effects and how to avoid them

Prolia is an FDA-approved brand-name medication manufactured by Amgen Inc. and is used to treat osteoporosis and bone loss. While Prolia is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Prolia include bone and joint pain. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Prolia and what you can do to avoid them.

What is Prolia (denosumab)?

Prolia is used specifically to treat:

  • Postmenopausal osteoporosis in women who have a high risk of bone fractures
  • Osteoporosis in men who have an increased risk of bone fractures
  • Bone loss in women who are receiving adjuvant aromatase inhibitor hormone therapy for breast cancer
  • Bone loss in men who are receiving androgen deprivation therapy (ADT) for prostate cancer

Prolia is not recommended to treat osteopenia. Osteopenia is a condition where your bones are not as strong as normal but not as weak as they would be if you had osteoporosis.

The active ingredient in Prolia is called denosumab. It helps counter bone loss and osteoporosis by reducing the rate at which your body loses bone tissue. Your body continually replaces old bone tissue with new bone tissue. Part of this process of bone turnover involves a protein called RANKL that helps produce a type of cell that breaks down bone. Denosumab works by blocking RANKL, stopping it from producing the cells that break down bone. This reduces the rate at which your body removes bone tissue, causing the bone mass to increase over time.

Prolia dosage

Prolia is available in solution form in the following doses: prefilled syringes containing 60 mg in 1 mL or single-use vials containing 60 mg in 1 mL.

Prolia is given by a healthcare professional as a subcutaneous injection every 6 months in the upper arm, upper thigh, or abdomen. Patients are advised to take calcium 1000 mg each day and 400 IU of vitamin D each day.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Prolia side effects

The most common possible side effects of Prolia in clinical trials include the following:

  • Arm and leg pain
  • Back pain
  • Bone pain and joint pain
  • Muscle pain
  • Hair loss
  • Constipation, abdominal pain, flatulence
  • Skin rashes and eczema
  • skin problems such as dryness, peeling, redness, itching, small bumps/patches, or blisters
  • Urinary tract infection
  • Frequent and painful urination
  • Blood in the urine

Prolia can cause more serious side effects, including:

  • Serious allergic reactions: low blood pressure, shortness of breath, tightness in your throat, swelling in your face and throat, itchiness, rash
  • Skin infections
  • Other serious infections
  • Jaw pain and jaw bone damage (osteonecrosis of the jaw)
  • Low calcium levels in the blood. Prolia is recommended in combination with calcium and vitamin D supplements.
  • Unusual fractures of the thigh bone

If you experience any of these serious side effects, stop taking Prolia and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is the best and safest treatment for osteoporosis in 2022?

Bisphosphonates such as Reclast, Fosamax, and Actonel (risedronate) are the first choice for osteoporosis treatment. Fosamax is taken as a once-weekly pill. Actonel is taken as a once-weekly or monthly pill. Reclast is given intravenously.

Switching from Fosamax to Prolia

Prolia is a monoclonal antibody that works with your immune system to prevent bone loss. Bisphosphonates (such as Fosamax) help increase the thickness of bone and prevent the breakdown of bone and has a different mechanism of action to Prolia. Discuss switching from Fosamax to Prolia with your doctor.

Which is safer Fosamax or Prolia?

Prolia and Fosamax have similar side effects. Like Fosamax, Prolia can cause osteonecrosis of the jaw and atypical fractures, and which of these two treatments is safest for you will depend on your medical condition and any other medicines you are taking. Speak to your doctor for medical advice.

Is taking Prolia worth the risk?

The National Women’s Health Network recommends that Prolia only be used as a treatment option in post-menopausal women suffering from severe osteoporosis or when other osteoporosis medications have not worked. Prolia has an extensive list of side effects. However, not all the side effects of Prolia from long-term use are known, and it is not clear if the benefits of using Prolia outweigh its risks.

Is Reclast Better than Prolia?

In studies, Prolia was seen to have a greater increase in spine bone mineral density/BMD (a measure of bone health) at 1 year than Reclast, but not significantly. Reclast also had a greater incidence of causing mild flu-like symptoms. Prolia is a relatively new medication, and patient numbers for the study were relatively low. Further studies are needed to investigate the efficacy of Prolia.

Is there a natural alternative to Prolia?

Alternative treatments for osteoporosis will depend on your age, sex, and the severity of your condition. Natural alternatives to Prolia include vitamin D supplements, dietary changes (such as avoiding fizzy drinks and caffeine), reducing stress, and a simple exercise plan.

Prolia drug interactions

Prolia can interact with other medications, including:

  • Medications that contain the same active ingredient as Prolia (denosumab), like Xgeva
  • Corticosteroids, like prednisone or dexamethasone

Before taking Prolia, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Prolia warnings & precautions

Don’t take Prolia if you:

  • Are allergic to the active ingredient denosumab
  • Are allergic to any of the other ingredients in Prolia (these are listed in the leaflet which comes with the medication)
  • Have low calcium levels in your blood (hypocalcemia)
  • Are under 18 years of age

Talk to your physician before taking Prolia if you:

  • Have low blood calcium levels (hypocalcemia)
  • Have had thyroid/parathyroid problems
  • Have stomach or intestinal problems
  • Have cancer
  • Have ever had severe kidney problems, kidney failure, or have been on dialysis
  • Have poor dental health or any problems with your teeth or mouth, like gum disease
  • Have had recent or planned dental procedures
  • Are a smoker (this can increase the risk of dental problems)
  • Have an allergy to latex (the cover of the pre-filled syringe contains a derivative of latex)
  • Are pregnant or trying to become pregnant. If you can become pregnant, you should use an effective form of birth control
  • Are breastfeeding or plan to breastfeed

You should always check with your healthcare provider before taking any medication, including Prolia, to make sure it is safe for you. Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Prolia.

How to avoid Prolia side effects

The best way to avoid side effects is to take Prolia as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Prolia that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Prolia. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Prolia.

6. Know the signs and symptoms of Prolia side effects

Signs and symptoms of side effects include joint and muscle pain. If you experience these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Prolia.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Prolia as needed.

Revlimid side effects and how to avoid them

Revlimid is an FDA (Food and Drug Administration) approved medication manufactured by Celgene Corporation, used to treat different types of cancer. While Revlimid is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Revlimid include joint and muscle pain. Less common but more serious side effects can include allergic reactions.

Learn more about the side effects of Revlimid and what you can do to avoid them.

What is Revlimid (lenalidomide)?

Revlimid is a medicine prescribed to adults to treat certain types of cancers that can affect your blood, including:

  • Multiple myeloma – alongside the medicine dexamethasone or as a maintenance treatment after a stem cell transplant
  • Myelodysplastic syndromes (MDS)
  • Mantle cell lymphoma (MCL) – when the disease has come back or worsens after other treatments
  • Follicular lymphoma – alongside the medicine rituximab
  • Marginal zone lymphomas– alongside the medicine rituximab

The active ingredient in Revlimid is called lenalidomide. Lenalidomide works in three main ways to minimize the symptoms of your condition. These include:

  • Blocking the development of cancerous blood cells by causing them to self-terminate
  • Stimulating your immune system to attack cancerous cells
  • Stopping blood vessels from developing inside cancerous tumors, starving the tumors of the oxygen and nutrients they need to grow

These three actions help to limit the number of cancerous cells you have in your body and how fast any tumors grow. This can provide relief from your symptoms and slow the progression of your cancer.

Is Revlimid a chemo?

Revlimid is not a chemo, it is a cancer treatment for myeloma and blood disorders called myelodysplastic syndromes.

How effective is Revlimid in treating multiple myeloma?

Revlimid does not improve survival rates overall in the population, but those who have received a stem cell transplant do live longer when using Revlimid.

Can Revlimid cure cancer?

Cancer can not be cured, but treatment with Revlimid can help control the symptoms and improve your quality of life.

Revlimid dosage

Revlimid is available in capsule form in doses of 2.5 mg, 5 mg, 10 mg, 15 mg, 20 mg, and 25 mg.

You are advised to read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How long does Revlimid stay in your system?

Revlimid will stay in your system for up to 4 weeks after your last dose.

How long can you take Revlimid?

Revlimid can be taken on days 1 to 21 of a 28-day cycle for up to 12 cycles.

What happens when you stop taking Revlimid?

Stopping taking Revlimid may worsen and increase the symptoms of your condition.

Revlimid side effects

The most common side effects of Revlimid in clinical trials include:

  • Headaches
  • Nose bleeds
  • Skin rashes, itching, dry skin
  • Nausea
  • Shortness of breath
  • Abdominal pain, loss of appetite
  • Diarrhea
  • Constipation
  • Tiredness or weakness
  • Coughs, a sore throat, dry mouth, and other symptoms of a cold
  • Upper respiratory tract infections
  • Bronchitis
  • Fever
  • Inflammation of your stomach and intestine (“stomach flu”)
  • Muscle cramps and muscle spasms
  • Joint pain, back pain
  • Swelling of your arms, hands, legs, feet, and skin
  • Shaking or trembling (tremors)
  • Sleep problems (insomnia)

Revlimid can cause more serious side effects, including:

  • Life-threatening allergic reactions to the medication
  • Birth defects or death of an unborn baby
  • Severe liver problems, including liver failure and death. Symptoms include yellowing of your skin or the white of. your eyes
  • Severe skin reactions that can be fatal
  • Tumor lysis syndrome (TLS) caused by the fast breakdown of cancer cells, which can cause kidney failure, an abnormal heart rhythm, seizures, and sometimes death
  • Low white blood cells (neutropenia) and low platelets (thrombocytopenia)
  • Worsening of your tumor (tumor flare reaction)
  • Thyroid problems
  • An increased risk of blood clots in the lung (pulmonary embolism), arm, or leg (deep vein thrombosis). Symptoms include shortness of breath, chest pain, or arm or leg swelling
  • An increased risk of early death in people who have mantle cell lymphoma (MCL)
  • An increased risk of death in people who have chronic lymphocytic leukemia (CLL) caused by heart problems like atrial fibrillation, heart attack, or heart failure
  • An increased risk of new cancers developing in people who take Revlimid with melphalan or a blood stem cell transplant

If you experience any of these serious side effects, stop taking Revlimid and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Revlimid affect your eyes?

Revlimid may cause eye problems such as blurred vision and cataracts.

Does Revlimid cause hair loss?

Hair loss is not a side effect of taking Revlimid but may be due to the condition you are being treated for. Speak to your doctor for medical advice if you are concerned about hair loss.

Revlimid drug interactions

Revlimid can interact with other medications, including:

  • Digoxin, taken to treat various heart conditions
  • Blood thinners (anticoagulants), such as warfarin
  • Erythropoietin stimulating agents, taken to stimulate your bone marrow to make red blood cells
  • Any hormone therapies that contain estrogen

Before taking Revlimid, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Revlimid warnings & precautions

Revlimid isn’t suitable for everyone. It can cause birth defects or the death of an unborn baby, so it mustn’t be taken by women who are pregnant or planning to become pregnant. Don’t try to become pregnant for at least four weeks before starting Revlimid, while taking it, or at least for four weeks after you’ve finished taking it. Carry out pregnancy tests on a regular basis to ensure you are not pregnant.

Revlimid can also pass into human semen. Men taking Revlimid should always use an effective form of birth control, such as condoms when having sex with a woman who is or who could become pregnant.

It is not known if Revlimid can pass into breast milk. Don’t breastfeed while taking Revlimid.

Don’t take Revlimid if:

  • Are allergic to the active ingredient lenalidomide
  • Are allergic to any of the other ingredients in Revlimid
  • Are under 18 years of age

Talk to your doctor before taking Revlimid if you:

  • Are taking any of the medications that could interact with Revlimid
  • Have any liver problems
  • Have any kidney problems or are on dialysis
  • Have any thyroid problems
  • Have had a serious skin rash caused by a thalidomide treatment
  • Are lactose intolerant
  • Are aged over 75

You should always check with your doctor or pharmacist before taking any medication, including Revlimid, to ensure it is safe.

How to avoid Revlimid side effects

The best way to avoid side effects is to take Revlimid as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Revlimid that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Revlimid. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Revlimid, as it can increase your risk of side effects. Speak to a healthcare professional about alcohol consumption while taking Revlimid.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Revlimid.

7. Know the signs and symptoms of Revlimid side effects

Signs and symptoms of side effects include abdominal pain and loss of appetite. If you experience these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Weight loss or weight gain are not side effects reported with the use of Revlimid. Speak to your doctor if you experience a change in your weight while using this treatment.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Revlimid.

10. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Revlimid as needed.

Movantik side effects and how to avoid them

Movantik is a brand-name medication manufactured by AstraZeneca. It is classified as a peripheral opioid receptor antagonist and is used for the treatment of opioid-induced constipation side effects of opioids. While Movantik is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Movantik include nausea and vomiting. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Movantik and what you can do to avoid them.

What is Movantik (naloxegol)?

Movantik is a medication prescribed to adults who have constipation caused by taking opioid painkillers to improve bowel movement. It’s formulated specifically for adults who take opioids for chronic non-cancer pain.

If your doctor prescribes you opioid medication, they may also prescribe Movantik at the same time. The medication is designed to stop opioids from affecting your bowels and giving you constipation. You take Movantik as a tablet with water.

Opioid medications cause constipation by attaching to the surface of cells in your bowels at locations called mu-receptors. This stimulates the mu-receptors, causing reactions in your bowel cells that remove fluid and slow the passage of waste through your bowels. This hardens your stools and makes it harder for your body to expel them.

Movantik helps to counter this. When you take Movantik, the active ingredient naloxegol (a PEGylated derivative of naloxone) binds with the mu-receptors instead of the opioids. This blocks the mu-receptors and stops the opioids from stimulating them and affecting your bowels.

Is Movantik a laxative?

Movantik is an opioid receptor antagonist used to treat the constipating side effects of opioids.

Can Movantik help with regular constipation?

Movantik is a medication prescribed to adults who have constipation caused by taking opioid painkillers. It’s formulated specifically for adults who take opioids for chronic non-cancer pain.

Movantik dosage

Movantik is available in tablet form in the following doses: 12.5 mg and 25 mg

Take Movantik on an empty stomach at least 1 hour before your first meal or 2 hours after the meal. If you are unable to swallow the tablet whole, crush the tablet and take it orally or via a nasogastric tube. Discontinue treatment with Movantik if opioid pain medication is discontinued. Take 25 mg once daily but reduce to 12.5 mg once daily if you are unable to tolerate 25 mg. Store Movantik at room temperature, away from moisture and light.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Can you take Movantik every day?

Take Movantik 25 mg once daily in the morning. Reduce the dosage to 12.5 mg once daily if you are unable to tolerate 25mg.

When is the best time to take Movantik?

Take Movantik orally once daily in the morning on an empty stomach 1 hour before or 2 hours after a meal.

What happens if you take Movantik with food?

Taking Movantik with food may increase its absorption into your bloodstream.

What happens when you stop taking Movantik?

You will stop taking Movantik if you stop receiving treatment with opioids. If you have constipation after stopping opioids, you will need to use an alternative treatment as Movantik will not be suitable. Stopping treatment with an opioid may also cause opioid withdrawal symptoms.

Movantik side effects

The most common possible side effects of Movantik include:

  • Headaches
  • Stomach pain
  • Flatulence
  • Nausea
  • Vomiting
  • Diarrhea

Movantik can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • Symptoms of opioid withdrawal include sweating, chills, worsening abdominal pain, diarrhea, irritability, and anxiety resulting in hospitalization
  • Severe stomach pain and/or diarrhea
  • Gastrointestinal perforations in the wall of your stomach or intestines

If you experience any of these serious side effects, stop taking Movantik and seek medical attention immediately. You are encouraged to report adverse reactions to prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Movantik cause weight gain?

Weight gain is a side effect experienced when taking Movantik. This is more common in females over the age of 60 that have been using Movantik for over 1 month.

Movantik drug interactions

Movantik can interact with other medications, including:

  • Azole antifungals such as ketoconazole, itraconazole
  • Boceprevir, indinavir, nelfinavir, ritonavir, tipranavir
  • Antibiotics such as clarithromycin
  • Methadone as therapy for pain
  • Moderate CYP3A4 inhibitors such as diltiazem, erythromycin, or verapamil
  • Strong CYP3A4 inducers such as rifampin, carbamazepine, and St. John’s Wort

Before taking Movantik, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Movantik contraindications

Don’t take Movantik if:

  • Are allergic to the active ingredient naloxegol
  • Are allergic to any of the other ingredients in Movantik
  • Have, or have ever had, a blockage in your bowels (intestinal obstruction)

Talk to your doctor before taking Movantik if you:

  • Regularly take laxatives
  • Have any stomach or bowel problems, like diverticulitis, colitis, or cancer
  • Have recently had surgery on your stomach or bowels
  • Have intestinal ulcers or tumors, Crohn’s, or diverticulitis
  • Have kidney disease
  • Have any liver problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is unknown if this medication passes into breast milk

You should also avoid eating grapefruit or drinking grapefruit juice when you take Movantik. Always check with your doctor or pharmacist before taking any medication, including Movantik, to ensure it is safe.

How to avoid Movantik side effects

The best way to avoid side effects is to take Movantik as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Movantik as recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Movantik. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Movantik. Movantik is taken when opioid treatments cause constipation. Alcohol will have a combined sedative effect when taken with opioids.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Movantik.

7. Know the signs and symptoms of Movantik side effects

Signs and symptoms of side effects include stomach pain and flatulence. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Movantik.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Movantik as needed.

Lialda side effects and how to avoid them

Lialda is an FDA (Food and Drug Administration) approved brand-name medication manufactured by Shire US Inc., used to treat ulcerative colitis. While Lialda is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Lialda include abdominal pain. Less common but more serious side effects can include kidney and liver problems.

Learn more about the side effects of Lialda and what you can do to avoid them.

What is Lialda (mesalamine)?

Lialda is a medicine prescribed to adults with a bowel disease called ulcerative colitis. It’s used to eliminate symptoms (remission), and to stop symptoms from coming back (maintenance of remission). Ulcerative colitis is an inflammatory disease that affects your bowels (your colon and your large intestine). It causes the lining of your bowels to become inflamed, disrupting how they work and causing damage. Small tears may develop that can bleed and form ulcers.

This inflammation and damage cause symptoms like abdominal (stomach) pain, feeling sick, diarrhea, fever, weight loss, and anemia. These can affect your quality of life, particularly if the symptoms become severe. Over time, ulcerative colitis can lead to inflammation of the liver (hepatitis) and even colon cancer.

There’s no cure for ulcerative colitis, but you can manage the disease with medication like Lialda. Lialda comes as a tablet that you swallow. It reduces inflammation in your bowels, helping to eliminate symptoms and stopping them from coming back.

Lialda active ingredients

The active ingredient in Lialda is called mesalamine. It helps to reduce inflammation in your body. Mesalazine works by blocking enzymes in your bowels, called cyclooxygenase and lipoxygenase. These enzymes produce a natural chemical called prostaglandin that triggers inflammation. By stopping these enzymes from working, less prostaglandin is produced, and less inflammation is triggered.

Lialda dosage

Lialda is available in tablet form containing 1.2g of mesalamine. The standard recommended dose of Lialda is typically two to four 1.2 g tablets once daily with food for up to 8 weeks.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What happens when you stop using Lialda?

Stopping treatment with Lialda does not cause side effects. However, symptoms of ulcerative colitis may become worse.

Is Lialda safe for long-term use?

Lialda can be taken long-term. Your doctor will, however, check to see how well your kidneys are working during treatment.

When is the best time to take Lialda?

Lialda should be taken with food once daily for up to 8 weeks.

Lialda side effects

The most common possible side effects of Lialda include the following:

  • Headaches
  • Gastrointestinal side effects – stomach pain, flatulence, colitis, diarrhea, constipation, nausea, vomiting, rectal polyp
  • Upper respiratory tract infection
  • Flu-like symptoms such as rhinitis, colds, and sore throat
  • Abnormal results from liver tests (that will show up in blood tests)

Lialda can cause more serious side effects, including:

  • Severe allergic reactions to the medication – swelling, trouble breathing, or chest pain
  • Mesalamine-induced acute intolerance syndrome that may be hard to distinguish from a severe ulcerative colitis flare-up
  • Stevens-Johnson syndrome – blistering and peeling of the skin
  • Abdominal pain, cramping, bloody diarrhea
  • Kidney problems, including inflammation of the kidneys (nephritis), kidney failure and kidney stones
  • Liver problems, including inflammation of the liver (hepatitis) and liver failure. Symptoms include loss of appetite, upper stomach pain, easy bruising or bleeding, jaundice, dark urine, clay-colored stools
  • Pancreatitis
  • Rises in blood pressure
  • Cardiac disorders such as pericarditis and myocarditis

If you experience any of these serious side effects, stop taking Lialda and seek medical attention immediately.

You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Lialda cause hair loss?

Hair loss is not a common side effect of Lialda. Be aware that ulcerative colitis, a condition for which you may be taking Lialda, can also cause hair loss.

Does Lialda cause weight gain?

Weight gain is not a side effect of taking Lialda. Weight gain and weight loss are, however, symptoms of ulcerative colitis.

Does Lialda cause fatigue?

Long-term use of Lialda may cause kidney problems, symptoms of which include fatigue and low energy.

Does Lialda affect the kidneys?

Lialda may cause inflammation of the kidneys with long-term use. Your doctor will monitor you for this side effect while taking Lialda.

How long do Lialda side effects last?

Most side effects of Lialda will last a few days or weeks. Side effects such as liver or kidney problems may last longer. Speak to your doctor for medical advice if you experience these long-term side effects.

Lialda drug interactions

Lialda can interact with other medications, including:

  • Azathioprine, taken to treat various immune system disorders
  • Antacids, taken to reduce stomach acidity and reduce heartburn, like Tums, Nexium, or Prilosec
  • Non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or naproxen

Before taking Lialda, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Lialda warnings & precautions

Don’t take Lialda if:

  • Are allergic to the active ingredient mesalamine, aspirin, sulfasalazine, or salicylates
  • Are allergic to any of the other ingredients in Lialda
  • Are allergic to any salicylates or aminosalicylates, like aspirin
  • Are under 18 years of age

Talk to your doctor before taking Lialda if you:

  • Are taking any of the medications that could interact with Lialda
  • Have a skin condition such as eczema.
  • Have, or have had kidney disease
  • Have, or have had any liver problems or liver disease
  • Have, or have had, a blockage in your digestive tract
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age

You should always check with your doctor or pharmacist before taking any medication, including Lialda, to ensure it is safe.

How to avoid Lialda side effects

The best way to avoid side effects is to take Lialda as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Lialda as recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Lialda. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Lialda as it can increase your risk of symptoms of ulcerative colitis.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Lialda.

7. Know the signs and symptoms of Lialda side effects

Signs and symptoms of side effects include stomach pains and flatulence. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Lialda.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Lialda as needed.

Lyrica side effects and how to avoid them

Lyrica is a brand-name FDA (U.S. Food and Drug Administration) approved medication manufactured by Pfizer Inc. It is classed as an anti-epileptic drug (anticonvulsant) and neuropathic pain agent and is used for the treatment of nerve pain as well as epilepsy. While Lyrica is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Lyrica include nausea and headaches. Less common but more serious side effects can include an increase in suicidal thoughts and behavior.

Learn more about the side effects of Lyrica and what you can do to avoid them.

What is Lyrica?

Lyrica is approved by the FDA to treat:

  • Epilepsy that causes partial-onset seizures (Lyrica is usually used alongside other anti-epilepsy treatments)
  • Fibromyalgia – widespread chronic pain
  • Neuropathic pain (nerve pain) caused by a spinal cord injury
  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN) caused by shingles

Lyrica is not recommended for the management of fibromyalgia or as adjunctive therapy for adult patients with partial-onset seizures. Lyrica contains pregabalin as the active ingredient. Pregabalin is chemically and structurally similar to gabapentin, with antiepileptic, analgesic, and anxiolytic properties.

Lyrica dosage

Lyrica is available in capsule form, in the following doses: 25mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, and 300 mg, and in oral solution form, in the following doses: 20 mg/ mL.

Your recommended and maximum daily dosage will be based on the condition you are being treated for. If you forget to take a dose of Lyrica, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.

Read the full prescribing information and medication guide for the full drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Lyrica side effects

The most common side effects of Lyrica include:

  • Headache
  • Fatigue
  • Constipation
  • Nausea
  • Blurred vision, dry mouth, and weight gain

More serious side effects of pregabalin, include:

  • Unusual bleeding or bruising
  • Muscle pain, tenderness, weakness, swelling of hands, ankles, or feet
  • Angioedema – may be associated with life-threatening respiratory compromise requiring emergency treatment
  • Serious allergic reactions such as hives, trouble breathing, fast or slow, shallow breathing, or swelling of the face, lips, or throat
  • Worsening symptoms of suicidal thoughts or behavior
  • Peripheral edema
  • Dizziness and somnolence
  • Increased seizure frequency may occur in patients with seizure disorders if treatment is rapidly discontinued

If you experience any of these serious side effects, stop taking Lyrica and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Lyrica have sexual side effects?

Lyrica can cause some sexual side effects. These include both a reduced and an increased interest in sex, not being able to get or maintain an erection (erectile dysfunction), delayed ejaculation, and an inability to achieve climax.

These sexual side effects aren’t experienced by the majority of people who take Lyrica, but you could get one or more of them. Talk to your physician if you’re worried about sexual side effects and if you experience them while taking Lyrica.

Does Lyrica cause weight gain?

One side effect of Lyrica is that it can cause weight gain in some people who take it. Most people won’t gain weight, though, as this side effect happens in around one in 10 of those who take Lyrica. Talk to your physician if you’re concerned about weight gain.

Can pregabalin damage your heart?

Patients prescribed Lyrica for diabetic neuropathy experience an increased risk for myocardial infarction, heart failure, peripheral vascular disease, deep vein thrombosis, stroke, and pulmonary embolism.

Lyrica drug interactions

Lyrica can interact with other medications, including:

  • Other treatments that may also cause drowsiness, sedation, or breathing problems – opioids, or cough relievers such as codeine, hydrocodone, alcohol, marijuana (cannabis)
  • Antidepressants, drugs for sleep or anxiety – alprazolam, lorazepam, and zolpidem
  • Muscle relaxants – carisoprodol, cyclobenzaprine
  • Antihistamines – cetirizine, diphenhydramine

Before taking Lyrica, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

How does Lyrica affect the elderly?

Elderly patients over the age of 65 are at an increased risk of side effects such as dizziness, confusion, blurred vision, and kidney problems.

Is Lyrica an opioid?

Lyrica is not an opioid or a narcotic. Lyrica can become habit-forming and is a Schedule V drug but has less potential to do so than most pain medicines, and this is unlikely if you use it as prescribed. Talk to your physician if you’re concerned about withdrawal symptoms or Lyrica becoming habit-forming.

Is pregabalin an effective painkiller?

Oral pregabalin plays an important role in pain relief in people with moderate or severe neuropathic pain after shingles or diabetes.

Lyrica warnings & precautions

Don’t take Lyrica if you:

  • Are allergic to the active ingredient pregabalin
  • Have had an allergic reaction to any of the other ingredients in Lyrica
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – Lyrica passes into breast milk

Talk to your doctor before using Lyrica if you:

  • Are taking any of the medications that could interact with Lyrica
  • Have chronic obstructive pulmonary disease (COPD)
  • Have a mood disorder, depression, or suicidal thoughts
  • Have heart problems (especially congestive heart failure)
  • Have a bleeding disorder, or low levels of platelets in your blood
  • Have kidney disease
  • Have diabetes (unless you are taking pregabalin to treat diabetic neuropathy)
  • Have a drug or alcohol addiction

You should always check with your doctor or pharmacist before taking any medication, including Lyrica, to ensure it is safe.

How to avoid Lyrica side effects

The best way to avoid side effects is to take Lyrica as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Lyrica as recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Lyrica. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Lyrica, as it can increase your risk of sleepiness, dizziness, and reduced concentration.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your caregiver if you experience any problems with your feet while taking Lyrica.

7. Know the signs and symptoms of Lyrica side effects

Signs and symptoms of side effects include blurred vision, dry mouth, and weight gain. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Lyrica.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Lyrica as needed.

Levemir side effects and how to avoid them

Levemir is a brand-name FDA (Food and Drug Administration) approved medication manufactured by Novo Nordisk Inc. It is classified as a long-lasting insulin and is used to treat diabetes. While Levemir is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Levemir include injection site reactions. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Levemir and what you can do to avoid them.

What is Levemir?

Levemir is a prescription medication used to lower high blood sugar levels (hyperglycemia) in adults and children with type 1 diabetes and type 2 diabetes mellitus. It’s a type of insulin that works in the same way as the insulin your body produces. A key difference, however, is the fact it’s long-lasting.

The active ingredient in Levemir is called insulin detemir, a type of synthetic (man-made) insulin that works in the same way as the insulin your body makes naturally. The only key difference is that insulin detemir has been designed to be longer acting than natural insulin, so it works over a longer time period.

When you inject Levemir under your skin, the insulin detemir is released into your bloodstream. It travels around your body in your blood and helps your cells absorb sugar. It can be active for up to 24 hours, so it can cover your insulin needs over the course of a full day.

Levemir dosage

Levemir is available in injection form as 3 mL Levemir FlexTouch prefilled insulin pens and 10 mL multiple dose vials.

Levemir is taken by injecting it under your skin (subcutaneous injection) into the thigh, upper arm, or abdomen using either a syringe or a pre-filled FlexTouch self-injecting pen. You typically inject Levemir once every 24 hours at the same time each day. Allow Levemir to reach room temperature before injecting a dose.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Levemir side effects

The most common possible side effects of Levemir in clinical trials include:

  • Injection site reactions such as itching, rashes, skin thickening, or pits forming in your skin (lipodystrophy)
  • Weight gain
  • Allergic reactions that can cause swelling of your face, tongue, or throat
  • Difficult or painful urination
  • Swelling (edema) of your hands and feet

Levemir can cause more serious side effects, including:

  • Serious allergic reactions to the medication that may be life-threatening and can cause anaphylaxis – skin rash, trouble breathing, fast heartbeats, feeling faint, or swollen face, tongue, or throat
  • Your blood sugar falls too low to dangerous levels (severe hypoglycemia). Keep a glucagon kit, glucose tablets, or fruit juice available in case of severe low blood sugar
  • Hypokalemia (low potassium level)

If you experience any of these serious side effects, stop taking Levemir and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Levemir affect the kidneys?

Levemir should not affect the kidneys, but kidney problems are common in those with diabetes.

Does Levemir cause hair loss?

Levemir is not associated with hair loss, but insulin resistance, which is associated with diabetes, may cause hair loss.

Does Levemir cause weight gain?

Levemir can cause weight gain, a common side effect of all types of insulin. Levemir causes weight increases in those with type 1 or type 2 diabetes but less than other long-acting insulins.

Does Levemir cause mood swings?

No, Levemir does not cause mood swings. Levemir may cause severe low blood sugar and result in changes in mood, such as anxiety.

Levemir drug interactions

Levemir can interact with other medications, including:

  • Antibiotics such as cinoxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin
  • Thiazolidinedione medications (TZDs) such as pioglitazone and rosiglitazone, taken to treat diabetes
  • Any other diabetes medications – metformin, glipizide, or other insulin products
  • Angiotensin II receptor blockers such as candesartan, losartan, and valsartan
  • Angiotensin-converting enzymes (ACE) inhibitors such as captopril, enalapril, and perindopril
  • Antidepressants, including monoamine oxidase inhibitors and selective serotonin reuptake inhibitors – phenelzine, selegiline, and sertraline
  • Beta 2-stimulants taken to treat asthma – salmeterol, formoterol
  • Beta-blockers taken to treat high blood pressure – propranolol, sotalol
  • Diuretics taken to make you lose water and salt, usually to treat high blood pressure – bumetanide, furosemide
  • Estrogen containing drugs, including birth control and hormone replacements
  • Fenofibrate taken to lower blood triglyceride levels
  • Thyroid hormones taken to treat thyroid gland disorders – levothyroxine, liothyronine

Before taking Levemir, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

What is the best time of day to take Levemir?

Take Levemir once daily with dinner or at bedtime, or twice a day in the morning, and then with dinner, at bedtime, or 12 hours after your morning dose.

Why do you take Levemir at night?

Levemir is a long-acting insulin that reduces fasting blood glucose levels more effectively with less nighttime hypoglycemia compared to other insulins.

Is Levemir safe during pregnancy?

Animal studies show an increased risk of fetal damage. The importance of this is not fully understood in humans. Further testing is needed to investigate the effects of Levemir during pregnancy.

Levemir warnings & precautions

Don’t take Levemir if you:

  • Are allergic to the active ingredient insulin detemir
  • Are allergic to any of the other ingredients in Levemir
  • Have diabetic ketoacidosis – a condition where high blood sugar causes high levels of ketones to build up in your body

Talk to your doctor before taking Levemir if you:

  • Are taking any of the medications that could interact with Levemir
  • Have heart failure
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – This medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Levemir, to ensure it is safe for you.

How to avoid Levemir side effects

The best way to avoid side effects is to take Levemir as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Levemir as recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Levemir. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Levemir, as it can increase your risk of hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Levemir.

7. Know the signs and symptoms of Levemir side effects

Signs and symptoms of side effects include injection site reactions and allergic reactions. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Levemir.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Levemir as needed.

Janumet XR side effects and how to avoid them

Janumet XR is a brand-name FDA (Food and Drug Administration) approved diabetes medication manufactured by Merck Sharp & Dohme Corp. It is used to help manage high blood sugar levels (hyperglycemia) in adults with type 2 diabetes mellitus. Janumet XR should be used alongside exercise and changes to your diet. While Janumet XR is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Janumet XR include upper respiratory infections. Less common but more serious side effects can include pancreatitis.

Learn more about the side effects of Janumet XR and what you can do to avoid them.

What is Janumet XR?

Janumet XR contains two active ingredients, called sitagliptin and metformin hydrochloride. These active ingredients reduce the amount of sugar released into your blood and increase the insulin produced by your pancreas. Janumet XR helps you lower your blood glucose levels.

Sitagliptin belongs to the drug class known as dipeptidyl peptidase-4/DPP-4 inhibitors, which increases the amount of insulin you produce after you’ve eaten. When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP that make your pancreas secrete insulin. As you continue to digest your food, these digestive hormones are broken down by an enzyme called DPP-4. This allows your levels of insulin to fall again. If you take Janumet XR, sitagliptin stops the DPP-4 enzyme from breaking down these digestive hormones. This keeps the hormones active for longer and makes you produce more insulin.

Metformin is classed as a biguanide and reduces how much sugar your liver releases into your blood. As your digestive system breaks down food, your liver releases sugar into your blood. If you take Janumet XR, metformin slows down the process that causes your liver to do this, lowering the amount of sugar released.

Janumet XR dosage

Janumet XR is available in extended-release tablet form in the following doses: Sitagliptin 100 mg/metformin HCl 1000 mg, sitagliptin 50 mg/metformin HCl 500 mg, and sitagliptin 50 mg/metformin HCl 1000 mg.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Janumet XR side effects

The most common possible side effects caused by Janumet XR in clinical trials include:

  • Headaches
  • Diarrhea
  • Nausea, vomiting
  • Back pain
  • Upset stomach
  • Loss of appetite
  • Abdominal pain
  • Upper respiratory tract infections, sore throat
  • Hypoglycemia – symptoms of low blood sugar include sweating, shaking, increased heart rate, hunger, dizziness, blurred vision, or tingling in the hands and feet

In rare instances, Janumet XR can cause more serious side effects, including:

  • Severe allergic reactions to the medication – skin rash, hives, itching, severe dizziness, trouble breathing
  • Risk of lactic acidosis – build-up of lactic acid in your body. Symptoms of lactic acidosis include breathing difficulties, shortness of breath, irregular heartbeat, tiredness, sleepiness, muscle pain, and stomach pain
  • Severe joint pain (arthralgia)
  • Anemia
  • Unusual skin blisters
  • Inflammation of the pancreas (pancreatitis)
  • Bullous pemphigoid (a rare but potentially severe skin reaction)
  • Kidney failure

If you experience any of these serious side effects, stop taking Janumet XR and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Janumet XR cause pancreatic cancer?

Pancreatic cancer is not a side effect of Janumet XR. Pancreatitis (inflammation of the pancreas), however, has been reported in trials of Janumet XR and Janumet.

Does Janumet XR cause erectile dysfunction?

Erectile dysfunction is not a side effect of Janumet XR. Diabetes may, however, cause erectile dysfunction. Speak to your doctor if you experience this side effect.

Does Janumet XR cause hair loss?

Hair loss is not a side effect of Janumet XR. Diabetes may, however, cause hair loss. Speak to your doctor if you experience this side effect.

Does Janumet XR cause weight gain?

Janumet XR does not normally cause weight gain but may cause a slight weight loss.

Does Janumet XR cause constipation?

Janumet XR may cause constipation, stomach upset, and abdominal pain as common side effects.

Does Janumet XR cause kidney damage?

Janumet XR may cause kidney problems as a side effect. Speak to your doctor if you have kidney problems before starting treatment with Janumet XR.

How long do Janumet XR side effects last?

Side effects of Janumet XR may go away and not require medical attention. Speak to your doctor for medical advice if you have long-term side effects.

Janumet XR drug interactions

Janumet XR can interact with other medications, including carbonic anhydrase inhibitors (such as zonisamide, acetazolamide, or dichlorphenamide), cationic drugs (such as amiloride, digoxin, morphine, or vancomycin, diuretics, corticosteroids, estrogens, oral contraceptives, nicotinic acid, and calcium channel blocking drugs.

Before taking Janumet XR, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Janumet XR warnings & precautions

Janumet XR isn’t suitable for everyone. Don’t take Janumet XR if you:

  • Are allergic to the active ingredients sitagliptin or metformin
  • Are allergic to any of the other ingredients in Janumet XR
  • Have type 1 diabetes
  • Have reduced kidney function
  • Have diabetic ketoacidosis – a potentially life-threatening condition caused by diabetes where you break down body fat too quickly
  • Are under 18 years of age

Talk to your physician before taking Janumet XR if you:

  • Are taking any of the medications that could interact with Janumet XR (listed in the section above)
  • Have a history of pancreatitis
  • Have heart problems, including congestive heart failure
  • Have vitamin B12 deficiency
  • Have liver disease or other liver problems
  • Have kidney disease
  • Are going to get an injection of dye or contrast agents for an x-ray
  • Drink alcohol often or binge drink alcohol
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age

Is Janumet XR good for diabetes?

Janumet XR reduces blood sugar levels in adults with type 2 diabetes. Janumet XR may be taken alone or with other medications to help reduce high blood sugar levels.

What is the best time of day to take Janumet XR?

It is best to take Janumet XR with your evening meal.

Why take Janumet XR in the evening?

You are advised to take Janumet XR with your evening meal to help reduce your chance of having an upset stomach.

How to avoid Janumet XR side effects

The best way to avoid side effects is to take Janumet XR as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Janumet XR recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Janumet XR. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Janumet XR, as it can increase your risk of lactic acidosis.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Janumet XR.

7. Know the signs and symptoms of Janumet XR side effects

Signs and symptoms of side effects include loss of appetite and an upset stomach. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Janumet XR.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Janumet XR as needed.

Janumet side effects and how to avoid them

Janumet is a brand-name diabetes medication manufactured by Merck Sharp & Dohme Corp. It is used to help manage high blood sugar levels in adults who have type 2 diabetes mellitus. Janumet should be used alongside exercise and changes to your diet. While Janumet is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Janumet include upper respiratory infections. Less common but more serious side effects can include pancreatitis.

Learn more about the side effects of Janumet and what you can do to avoid them.

What is Janumet?

Janumet contains two active ingredients, called sitagliptin and metformin hydrochloride. These active ingredients reduce the amount of sugar released into your blood and increase the insulin produced by your pancreas. Janumet helps you lower your blood glucose levels.

Sitagliptin belongs to the drug class known as dipeptidyl peptidase-4/DPP-4 inhibitors, which increases the amount of insulin you produce after you’ve eaten. When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP that make your pancreas secrete insulin. As you continue to digest your food, these digestive hormones are broken down by an enzyme called DPP-4. This allows your levels of insulin to fall again. If you take Janumet, sitagliptin stops the DPP-4 enzyme from breaking down these digestive hormones. This keeps the hormones active for longer and makes you produce more insulin.

Metformin is classed as a biguanide and reduces how much sugar your liver releases into your blood. As your digestive system breaks down food, your liver releases sugar into your blood. If you take Janumet, metformin slows down the process that causes your liver to do this, lowering the amount of sugar released.

Janumet dosage

Janumet is available in tablet form in the following doses: Sitagliptin 50 mg/metformin 500 mg and sitagliptin 50 mg/metformin 1000 mg. It is also available as Janumet XR (extended-release) long-acting oral tablets.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Janumet side effects

The most common possible side effects caused by Janumet in clinical trials include the following:

  • Headaches
  • Diarrhea
  • Nausea, vomiting
  • Back pain
  • Upset stomach
  • Loss of appetite
  • Abdominal pain
  • Upper respiratory tract infections, sore throat
  • Hypoglycemia – symptoms of low blood sugar include sweating, shaking, increased heart rate, hunger, dizziness, blurred vision, or tingling in the hands and feet

In rare instances, Janumet can cause more serious side effects, including:

  • Severe allergic reactions to the medication – rash, hives, itching, severe dizziness, trouble breathing
  • Risk of lactic acidosis – build-up of lactic acid in your body. Symptoms of lactic acidosis include breathing difficulties, shortness of breath, irregular heartbeat, tiredness, sleepiness, muscle pain, and stomach pain
  • Severe joint pain (arthralgia)
  • Anemia
  • Unusual skin blisters
  • Inflammation of the pancreas (pancreatitis)
  • Bullous pemphigoid (a rare but potentially severe skin reaction)
  • Kidney failure

If you experience any of these serious side effects, stop taking Janumet and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Janumet cause pancreatic cancer?

Pancreatic cancer is not a side effect of Janumet. Pancreatitis (inflammation of the pancreas), however, has been reported in trials of Janumet and Janumet XR.

Does Janumet cause erectile dysfunction?

Erectile dysfunction is not a side effect of Janumet. Diabetes may, however, cause erectile dysfunction. Speak to your doctor if you experience this side effect.

Does Janumet cause hair loss?

Hair loss is not a side effect of Janumet. Diabetes may, however, cause hair loss. Speak to your doctor if you experience this side effect.

Does Janumet cause weight gain?

Janumet does not normally cause weight gain but may cause a slight weight loss.

Does Janumet cause constipation?

Janumet may cause constipation, stomach upset, and abdominal pain as common side effects.

Does Janumet cause kidney damage?

Janumet may cause kidney problems as a side effect. Speak to your doctor if you have kidney problems before starting treatment with Janumet.

How long do Janumet side effects last?

Side effects of Janumet may go away and not require medical attention. Speak to your doctor for medical advice if you have long-term side effects.

Janumet drug interactions

Janumet can interact with other medications, including carbonic anhydrase inhibitors (such as zonisamide, acetazolamide, or dichlorphenamide), cationic drugs (such as amiloride, digoxin, morphine, or vancomycin, diuretics, corticosteroids, estrogens, oral contraceptives, nicotinic acid, and calcium channel blocking drugs.

Before taking Janumet, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Janumet warnings & precautions

Janumet isn’t suitable for everyone. Don’t take Janumet if you:

  • Are allergic to the active ingredients sitagliptin or metformin
  • Are allergic to any of the other ingredients in Janumet
  • Have type 1 diabetes
  • Have reduced kidney function
  • Have diabetic ketoacidosis – a potentially life-threatening condition caused by diabetes where you break down body fat too quickly
  • Are under 18 years of age

Talk to your physician before taking Janumet if you:

  • Are taking any of the medications that could interact with Janumet (listed in the section above)
  • Have a history of pancreatitis
  • Have heart problems, including congestive heart failure
  • Have vitamin B12 deficiency
  • Have liver disease or other liver problems
  • Have kidney disease
  • Are going to get an injection of dye or contrast agents for an x-ray
  • Drink alcohol often or binge drink alcohol
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age

Is Janumet good for diabetes?

Janumet reduces blood sugar levels in adults with type 2 diabetes. Janumet may be taken alone or with other medications to help reduce high blood sugar levels.

How to avoid Janumet side effects

The best way to avoid side effects is to take Janumet as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Janumet as recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Janumet. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Janumet as it can increase your risk of lactic acidosis.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Janumet.

7. Know the signs and symptoms of Janumet side effects

Signs and symptoms of side effects include loss of appetite and an upset stomach. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Janumet.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Janumet as needed.

Lantus side effects and how to avoid them

Lantus is an FDA (U.S. Food and Drug Administration) approved brand-name medication manufactured by Sanofi-Aventis. It is classified as a long-acting insulin and is used for diabetes treatment. While Lantus is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Lantus include injection site reactions. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Lantus and what you can do to avoid them.

What is Lantus?

Lantus is prescribed to reduce high blood sugar levels (hyperglycemia) in adults and children aged 6 years and over with type 1 diabetes or adults with type 2 diabetes mellitus.

Lantus works in the same way as the insulin your body naturally produces. The medication helps your cells absorb sugar from your blood. As it is a slow-acting version of insulin. One injection can give you all the insulin you need over 24 hours. You inject Lantus under your skin subcutaneously using a syringe or a pre-filled injectable SoloStar pen.

The active ingredient in Lantus is called insulin glargine, a type of insulin that is man-made. Insulin glargine works in a similar way to the insulin your body makes naturally, except it’s been designed to be slower acting to work over a longer period.

When you inject Lantus under your skin, the insulin glargine is released into your bloodstream. It travels around your body and attaches to cells that need sugar. This causes your cells to release a substance that helps them absorb sugar from your blood. Insulin glargine can be active for up to 24 hours, so it can cover your insulin needs for up to a day.

Lantus dosage

Lantus is available in injection form in the following doses: 10 mL multiple-dose vials and 3 mL Lantus SoloStar prefilled insulin pens.

Individualize your insulin dose based on your diabetes, metabolic requirements, blood glucose results, and your glycemic control goal. Inject subcutaneously into the abdomen, thigh, or upper arm once daily at any time, at the same time each day. Rotate the injection site to reduce the risk of lipodystrophy and localized cutaneous amyloidosis.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Lantus side effects

The most common side effects of Lantus include:

  • Allergic reactions that can cause swelling of your face, tongue, or throat
  • Injection site reactions, like itching, rashes, skin thickening, or pits forming in your skin (lipodystrophy)
  • Hypoglycemia (carry glucagon to help increase your blood sugar if needed)
  • Edema (fluid retention)
  • Blurred vision
  • Painful or difficult urination
  • Weight gain

Lantus can cause more serious side effects, including:

  • Severe allergic reactions, including anaphylaxis that may be life-threatening – skin rash, trouble breathing, fast heartbeats, feeling faint, shakiness, or swelling in your face, tongue, or throat
  • Severe hypoglycemia
  • Heart failure, if you take Lantus with other medications called TZDs (thiazolidinediones)
  • Low potassium levels in your blood (hypokalemia)

If you experience any of these serious side effects, stop taking Lantus and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Lantus cause cancer?

Insulin increases the production and death of cells, increasing the risk of cancer developing. Long-term use of insulin increases your risk for prostate, breast, and colorectal cancers.

Does Lantus cause weight gain?

Lantus may cause weight gain. Speak to your healthcare provider for medical advice if you experience this side effect.

Does Lantus cause joint pain?

Lantus may cause joint pain as a side effect of using Lantus. Joint pain only occurs in adults using Lantus to treat type 2 diabetes. Joint pain is not seen in adults or children using Lantus for the treatment of type 1 diabetes.

Lantus drug interactions

Lantus can interact with other medications, including:

  • Thiazolidinedione medications
  • Any other diabetes medications, such as metformin or pioglitazone
  • Beta-blockers
  • Angiotensin-converting enzyme (ACE) inhibitors
  • Fibrates
  • Corticosteroids
  • Protease inhibitors
  • Diuretics
  • Clonidine, taken to treat a range of conditions, including high blood pressure, ADHD, drug withdrawal, menopausal flushing, and certain pain conditions
  • Guanethidine and reserpine, taken to treat high blood pressure

Before taking Lantus, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Lantus warnings & precautions

You should not use Lantus if you:

  • Are allergic to the active ingredient insulin glargine
  • Have a known hypersensitivity to any of the other ingredients in Lantus
  • Are under 6 years of age for type 1 diabetes
  • Are under 18 years of age for type 2 diabetes
  • Have diabetic ketoacidosis – a condition where high blood sugar causes high levels of ketones to build up in your body

Talk to your doctor before using Lantus if you:

  • Have any heart problems
  • Have any have liver or kidney disease
  • Have low levels of potassium in your blood
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age

You should always check with your doctor or pharmacist before taking any medication, including Lantus, to make sure it is safe for you.

Semglee vs Lantus

Semglee contains insulin glargine-yfgn, a different form of insulin glargine to Lantus. Semglee is biosimilar to Lantus, meaning there is no clinical difference between them. Semglee is as effective as Lantus in helping with blood sugar control but will also have the same side effects and contraindications.

Why is Lantus given at night?

Lantus is a long-acting insulin that reduces fasting blood glucose levels more effectively with less nighttime hypoglycemia compared to other insulins.

How to avoid Lantus side effects

The best way to avoid side effects is to take Lantus as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Lantus recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Lantus. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Lantus, as it can increase your risk of hypoglycemia (low blood sugar levels).

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Lantus.

7. Know the signs and symptoms of Lantus side effects

Signs and symptoms of side effects include allergic reactions. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Lantus.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Lantus as needed.

Genvoya side effects and how to avoid them

Genvoya is a brand-name medication manufactured by Gilead Sciences, Inc. for HIV treatment. While Genvoya is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Genvoya include nausea and vomiting. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Genvoya and what you can do to avoid them.

What is Genvoya prescribed for?

Genvoya is a medication taken to treat HIV-1 infection. It’s prescribed to adults and children over 12 years old who weigh at least 77 lbs (35kg). Genvoya reduces the amount of the HIV virus in your body (viral load). This can help your immune system to work better and can lower your chances of getting HIV complications, like other infections and cancer.

Genvoya contains a mix of four active ingredients; emtricitabine, tenofovir alafenamide, elvitegravir, and cobicistat. They work together to reduce the amount of the HIV virus in your body. The HIV virus copies itself by invading your cells and inserting itself into your DNA. It then takes advantage of your body’s natural DNA-copying process to make copies of itself. Emtricitabine, tenofovir alafenamide, and elvitegravir are antiretroviral therapy that stops this from happening.

Elvitegravir is a type of antiviral called an integrase inhibitor. It stops the HIV virus from inserting itself into your DNA. Emtricitabine and tenofovir alafenamide are antivirals called nucleoside reverse transcriptase inhibitors (NRTIs). They stop the virus from being copied when your DNA is copied. The fourth active ingredient, cobicistat, boosts the effects of elvitegravir. It stops enzymes in your liver from breaking down elvitegravir, keeping it working for longer.

Genvoya dosage

Genvoya is available in tablet form. Each tablet contains 150 mg elvitegravir, 150 mg cobicistat, 10 mg tenofovir alafenamide fumarate and 200 mg emtricitabine.

Take one tablet daily with food. Avoid antacids containing aluminum, magnesium, or calcium within 2 hours before taking Genvoya or 2 hours after you take Genvoya, as they can make it more difficult for your body to absorb cobicistat, elvitegravir, emtricitabine, and tenofovir.

If you forget to take a dose of Genvoya, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at your normal scheduled time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Genvoya side effects

The most common possible side effects of Genvoya in clinical trials include:

  • Nausea, vomiting
  • Stomach pain, gas, diarrhea
  • Headaches, dizziness
  • Tiredness
  • Skin rashes
  • Abnormal dreams

In rare instances, Genvoya can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • A potentially life-threatening condition called lactic acidosis caused by a build-up of lactic acid in your blood. Symptoms include muscle pain, trouble breathing, stomach pain, dizziness, or tiredness
  • Severe liver problems that can be fatal
  • A worsening of a hepatitis B infection if you have one
  • New or worsening kidney problems, including kidney disease or kidney failure
  • Changes in your immune system, including a strengthening of your immune system (immune reconstitution syndrome)
  • Changes in body fat and body fat distribution – often reduced fat around the legs, arms, and face, and increased fat around the back, neck, trunk, and breast
  • High cholesterol

If you experience any of these serious side effects, stop taking Genvoya and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Genvoya drug interactions

Genvoya can interact with other medications, including:

  • Alfuzosin hydrochloride
  • Carbamazepine, phenobarbital, phenytoin
  • Ergot-containing medicines, like dihydroergotamine mesylate or ergotamine tartrate
  • Other HIV medications, such as ritonavir
  • Cobicistat, elvitegravir, emtricitabine, lamivudine, or tenofovir
  • Lovastatin
  • Midazolam, when taken orally
  • Pimozide
  • Rifampin
  • Sildenafil, when used to treat pulmonary arterial hypertension
  • Simvastatin
  • Triazolam
  • Hormonal birth control such as pills, patches, or rings.
  • Herbal remedies used to treat depression and anxiety that contain St. John’s wort

Before taking Genvoya, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Genvoya contraindications

Genvoya isn’t suitable for everyone. Don’t take Genvoya if you:

  • Are allergic to the active ingredients elvitegravir, cobicistat, emtricitabine, tenofovir alafenamide
  • Are allergic to any of the other ingredients in Genvoya
  • Are under 12 years of age, or are over 12 years old but weigh less than 77lbs (35kg)

Talk to your doctor before taking Genvoya if you:

  • Are taking any of the medications that could interact with Genvoya
  • Have a hepatitis B or C infection
  • Have any liver problems
  • Have any kidney problems
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed – It is unknown if elvitegravir, cobicistat, or tenofovir alafenamide pass into breast milk
  • Are lactose intolerant

You should always check with your doctor or pharmacist before taking any medication, including Genvoya, to make sure it is safe for you.

Does Genvoya cause weight gain?

Weight gain is not a recognized side effect of Genvoya. Speak to your doctor for medical advice if you experience this side effect.

What happens if you stop taking Genvoya?

Patients with HIV and hepatitis B virus may have worsening hepatitis B (HBV), which can lead to liver failure when stopping Genvoya.

Does Genvoya cause liver damage?

Genvoya may cause liver problems such as lactic acidosis and an enlarged liver. Lactic acidosis is a buildup of lactic acid in your body that can lead to severe liver problems.

How to avoid Genvoya side effects

The best way to avoid side effects is to take Genvoya as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Genvoya recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Genvoya. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Genvoya.

6. Know the signs and symptoms of Genvoya side effects

Signs and symptoms of side effects include stomach pain, nausea, and vomiting. If you experience any of these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Genvoya.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Genvoya as needed.

Glyxambi side effects and how to avoid them

Glyxambi is a brand-name medication manufactured by Boehringer Ingelheim Pharmaceuticals, Inc., used to help manage blood sugar levels in patients with type 2 diabetes. While Glyxambi is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Glyxambi include upper respiratory tract infections. Less common but more serious side effects can include serious allergic reactions. Learn more about the side effects of Glyxambi and what you can do to avoid them.

What is Glyxambi?

Glyxambi is a diabetes medication used to reduce high blood sugar levels if you have type 2 diabetes. Type 2 diabetes mellitus is a condition where you have high blood sugar levels most of the time. Glyxambi encourages your pancreas to produce insulin for longer, helping you absorb more glucose from your blood. It also causes you to lose more sugar when you urinate. These two effects can help you maintain lower blood sugar levels.

Glyxambi contains empagliflozin, a sodium-glucose co-transporter inhibitor (SGLT2 inhibitor), and linagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4 inhibitor).

Empagliflozin increases the amount of sugar in your urine. An enzyme called SGLT2 reabsorbs sugar from your urine to allow your body to use as much of the sugar you eat as possible. But empagliflozin blocks the SGLT2 enzyme. This limits the amount of sugar you absorb from your urine and means you lose more when you urinate. Empagliflozin is also used to reduce the risk of death from heart attacks and stroke in people with type 2 diabetes and cardiovascular disease.

Linagliptin increases the amount of insulin you produce after you’ve eaten. When you digest food, you release digestive hormones that make your pancreas secrete insulin. As you continue to digest your food, these digestive hormones are broken down by an enzyme called DPP-4 to allow your levels of insulin to fall again. Linagliptin stops this from happening. It blocks the DPP-4 enzyme breaking down these digestive hormones, keeping them active for longer, making you produce more insulin.

Glyxambi dosage

Glyxambi is available in tablet form in the following doses: 10 mg empagliflozin/5 mg linagliptin and 25 mg empagliflozin/5 mg linagliptin.

Glyxambi is usually taken once a day, with or without food. If you forget to take Glyxambi, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.

You are advised to read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Glyxambi side effects

The most common side effects caused by Glyxambi include the following:

  • Cough, sore throat
  • Inflamed nose or throat
  • Upper respiratory tract infections
  • Itching, skin rash
  • Increased thirst and urination
  • Genital yeast infections
  • An increase in the blood enzyme amylase
  • An increase in the pancreas enzyme lipase

In rare instances, Glyxambi can cause more serious side effects, including:

  • Life-threatening allergic reactions – hives, itching, peeling skin, trouble swallowing, difficulty breathing, swelling of the face, lips, tongue or throat
  • Heart failure
  • Gallstones
  • Inflammation of the pancreas (pancreatitis)
  • Kidney problems
  • Serious urinary tract infections
  • Hypoglycemia – having too low blood sugar (symptoms of low blood sugar include lightheadedness, shakiness, and fainting)
  • Increased cholesterol
  • Diabetic ketoacidosis – a buildup of ketones in your blood (symptoms include nausea, vomiting, abdominal pain, confusion, lightheadedness, unusual tiredness, shortness of breath, and trouble breathing
  • Serious skin reactions that can cause blistering and shedding of skin
  • Bullous pemphigoid, skin reactions such as rash, urticaria
  • Necrotizing fasciitis – a rare but serious bacterial infection of the tissue under the skin
  • Fournier’s gangrene (an infection of the genital area)
  • Urosepsis
  • Severe joint pain (arthralgia)

If you experience any of these serious side effects, stop taking Glyxambi and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Glyxambi cause weight loss?

No. Weight loss or weight gain are not side effects of Glyxambi. Speak to your doctor if you experience this side effect when taking Glyxambi.

Does Glyxambi cause kidney damage?

Glyxambi may cause infections that spread to the kidneys causing kidney damage and kidney failure.

Glyxambi drug interactions

Glyxambi can interact with other medications. When this happens, it can change how Glyxambi and the other medications work and make some side effects more likely. Tell your prescribing physician about all drugs you’re taking, particularly:

  • Insulin secretagogues or any other medications, such as sulfonylureas that can lower your blood sugar
  • Any diuretics (water pills)
  • Rifampin, an antibiotic used to treat tuberculosis

Before taking Glyxambi, be sure to tell your doctor about all of the medications you are taking, including over-the-counter drugs and supplements, to ensure they are safe to take at the same time.

Glyxambi contraindications

Glyxambi isn’t suitable for everyone. Don’t take Glyxambi if you:

  • Are allergic to the active ingredients empagliflozin or linagliptin
  • Are allergic to any of the other ingredients in Glyxambi
  • Have type 1 diabetes
  • Have severe kidney problems or are on dialysis
  • Are under 18 years of age

Talk to your physician before taking Glyxambi if you:

  • Are taking any of the medications that could interact with Glyxambi
  • Have kidney disease or any other kidney problems
  • Have liver problems
  • Have hypotension (low blood pressure)
  • Have a history of pancreatitis
  • Have a history of genital yeast infections
  • Have a history of urinary tract infections or problems with urination
  • Are due to have surgery
  • Are eating less due to illness, surgery, or a change in your diet
  • Often drink alcohol or binge drink alcohol
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 75 years of age

You should always check with your doctor or pharmacist before taking any medication, including Glyxambi, to ensure it is safe for you.

Glyxambi vs Jardiance

Glyxambi contains a combination of empagliflozin and linagliptin. Jardiance contains empagliflozin only. While Glyxambi may be used to treat the same conditions as Jardiance, it may also be used to treat additional medical conditions. Glyxambi will, however, also cause certain side effects that Jardinace does not.

What are the benefits of Glyxambi?

Glyxambi is used in combination with diet and exercise to control high blood sugar in people with type 2 diabetes, helping to prevent kidney damage, loss of limbs, and sexual function problems.

Can you take Glyxambi and metformin together?

Empagliflozin and metformin are used in combination with a healthy diet and exercise to treat high blood sugar caused by type 2 diabetes.

How to avoid Glyxambi side effects

The best way to avoid side effects is to take Glyxambi as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Glyxambi that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Glyxambi. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

You may drink alcohol while taking Glyxambi, however, drinking more than 2 units of alcohol each day can increase your risk of low blood sugar levels.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Glyxambi.

7. Know the signs and symptoms of Glyxambi side effects

Signs and symptoms of side effects include upper respiratory tract infections. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Glyxambi.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Glyxambi as needed.

Daliresp side effects and how to avoid them

Daliresp is a brand-name medication manufactured by Forest Laboratories. It is classified as a PDE4 inhibitor used to treat lung diseases such as COPD. While Daliresp is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Daliresp include back pain and muscle spasms. Less common but more serious side effects can include suicidal thoughts and behavior.

Learn more about the side effects of Daliresp and what you can do to avoid them.

What is Daliresp (roflumilast)?

Daliresp is a prescription medication given to adults to treat severe chronic obstructive pulmonary disease (COPD). It is used to slow the progression of COPD and to decrease the number of flare-ups a patient has. The active ingredient in Daliresp is roflumilast, a phosphodiesterase-4 inhibitor (PDE4 inhibitor) that reduces inflammation in your lungs and airways, helping you to breathe more easily.

How does Daliresp help COPD?

Daliresp is FDA-approved as an add-on therapy to reduce the number of exacerbations in patients with severe COPD. It works by stopping your body from breaking down a substance called cyclic adenosine monophosphate (cAMP). This is a type of signaling molecule that can dampen down inflammation in your body. Roflumilast blocks an enzyme called phosphodiesterase-4 that breaks down cAMP. This stops the enzyme from working, causing levels of cAMP to rise and inflammation in your body to decrease. By reducing inflammation in your airways and lungs, roflumilast opens them up and lets you breathe in more air.

Does Daliresp help you breathe better?

Yes. Daliresp is used in adults with severe COPD to reduce the number of flare-ups or the worsening of COPD symptoms. Daliresp should not, however, be used to treat sudden breathing problems.

Daliresp dosage

Daliresp is available in tablet form in the following doses: 500 mcg. The recommended starting dose of Daliresp is typically one 500 mcg tablet per day, with or without food. Your doctor may increase your dose if needed over time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

When is the best time to take Daliresp?

Take Daliresp once each day, with or without food.

What happens if you stop taking Daliresp?

You are advised not to stop using Daliresp without speaking to your doctor first.

How long does it take for Daliresp to start working?

You may need to take Daliresp for several weeks before it starts to work. Speak to your doctor for medical advice if your symptoms do not improve using this medication.

Daliresp side effects

The most common side effects of Daliresp in clinical trials include the following:

  • Headaches
  • Dizziness
  • Back pain
  • Muscle spasms
  • Nausea
  • Diarrhea
  • Loss of appetite
  • Weight loss
  • Trouble sleeping
  • Flu-like symptoms

Sometimes, Daliresp can cause more serious side effects. When these occur, they can include:

  • Severe allergic reactions to the medication
  • An increased risk of mental health problems, including new or worsening anxiety and depression, and thoughts of suicide
  • Weight loss, which can become harmful if you lose too much weight

If you experience any of these serious side effects, stop taking Daliresp and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

How long do the side effects of Daliresp last?

In clinical trials, people who experienced diarrhea and nausea at the beginning of their treatment usually saw these side effects stop after around 4 weeks.

Daliresp drug interactions

Daliresp can interact with other medications, including:

  • Antiviral medications – ritonavir, atazanavir, indinavir, saquinavir, or nelfinavir
  • Antibiotics – rifampicin, clarithromycin, erythromycin, or telithromycin
  • Antifungal medications – ketoconazole and itraconazole
  • Anticonvulsant medications – carbamazepine, phenobarbital, or phenytoin
  • Birth control pills
  • CYP3A4 inhibitors or dual inhibitors that block CYP3A4 and CYP1A2 – fluvoxamine, enoxacin, cimetidine

Before taking Daliresp, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Daliresp and prednisone

You may use Daliresp with prednisone, but you may not need prednisolone if the Daliresp works properly.

Daliresp contraindications

Daliresp is not a bronchodilator and should not be used to treat sudden and severe onsets of symptoms. Use your rescue inhaler to treat sudden and severe symptoms.

Do not take Daliresp if you:

  • Are allergic to the active ingredient roflumilast
  • Are allergic to any of the other ingredients in Daliresp
  • Have moderate to severe liver problems (C to D on the Child-Pugh scale)
  • Are under 18 years of age

Talk to your doctor before taking Daliresp if you:

  • Are taking any of the medications that could interact with Daliresp
  • Have a history of mood disorder or other mental health problems, particularly depression and/or suicidal thoughts and behaviors
  • Have any problems with your liver
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Daliresp, to ensure it is safe for you.

How to avoid Daliresp side effects

The best way to avoid side effects is to take Daliresp as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Daliresp that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Daliresp. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Daliresp as it can increase your risk of ……

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Daliresp.

7. Know the signs and symptoms of Daliresp side effects

Signs and symptoms of side effects include back pain and muscle spasms. If you experience these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Daliresp may cause weight loss. If you experience this side effect while taking Daliresp, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Daliresp.

10. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Daliresp as needed.

Belsomra side effects and how to avoid them

Belsomra is an FDA-approved brand-name medication manufactured by Merck & Co., Inc. It is classified as a sedative-hypnotic and is used to treat insomnia in adults who have trouble falling asleep, remaining asleep, or both. While Belsomra is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Belsomra include unusual dreams. Less common but more serious side effects can include suicidal thoughts and behavior.

Learn more about the side effects of Belsomra and what you can do to avoid them.

What is Belsomra (suvorexant)?

Belsomra is an orexin receptor antagonist indicated for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance. Belsomra is a Schedule IV federally controlled substance because it can be abused or cause dependence.

Belsomra dosage

Belsomra is available in tablet form in the following doses: 5 mg, 10 mg, 15 mg, and 20 mg.

The recommended dose is 10 mg, no more than once per night. Use Belsomra within 30 minutes of going to bed, with at least 7 hours of sleep planned. The dose can be increased if the 10 mg dose is well tolerated but not effective. Do not exceed 20 mg once daily. The onset of action may be delayed if taken with or soon after a meal.

You are advised to read the medication guide provided with this medicine for the full prescribing and drug information, and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Belsomra side effects

The most common side effects of Belsomra in clinical studies compared to placebo include:

  • Somnolence and sleepiness
  • Dry mouth
  • Daytime drowsiness – do not drive, use machinery, or do anything that needs alertness the next day
  • Abnormal dreams

In rare instances, Belsomra can cause more serious side effects. These can include:

  • Behavioral changes
  • Worsening depression and suicidal thoughts
  • Sleep paralysis – hypnagogic/hypnopompic hallucinations and cataplexy-like symptoms
  • Complex sleep behaviors – sleep-driving, sleepwalking, preparing and eating food, or having sex while not fully awake. This risk increases with dose, with the use of CNS depressants, and with alcohol
  • Compromised respiratory function

Your doctor will assess the benefits of using Belsomra against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Belsomra to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the side effects of Belsomra in the elderly?

Elderly patients are at a greater risk of falls due to side effects such as drowsiness caused by Belsomra.

Does Belsomra cause weight gain?

Belsomra should not cause weight gain or weight loss. Speak to your doctor for medical advice if you experience changes in your weight while using this medication.

Does Belsomra cause memory loss?

Varying degrees of memory loss have been reported when using Belsomra. Speak to your doctor for medical advice if you experience this side effect.

Belsomra drug interactions

Belsomra can interact with other medications. These include:

  • CYP3A inhibitors – fluconazole, ketoconazole, itraconazole, posaconazole, clarithromycin, erythromycin, nefazodone, ritonavir, saquinavir, nelfinavir, indinavir, boceprevir, telaprevir, telithromycin, fosamprenavir, grapefruit juice, imatinib, diltiazem, verapamil
  • Strong CYP3A inducers – rifampin, carbamazepine, and phenytoin
  • Digoxin
  • Other CNS depressants such as benzodiazepines, opioids, tricyclic antidepressants, and alcohol
  • Sedatives such as zolpidem

This list is not exhaustive, and other prescription drugs may interact with Belsomra. Talk to your doctor, nurse or pharmacist before taking any prescription or over-the-counter drugs (including any herbal medicines or supplements).

Belsomra contraindications

You should not use Belsomra if you:

  • Are allergic to the active ingredient suvorexant
  • Have had an allergic reaction to any of the other ingredients in Belsomra
  • Have narcolepsy
  • Are pregnant or are planning to become pregnant
  • Have severe hepatic impairment

Talk to your doctor before using Belsomra if you:

  • Are taking any of the medications that could interact with Belsomra
  • Are breastfeeding or are planning to breastfeed – it is unknown if suvorexant passes into breast milk
  • Have liver disease
  • Have lung disease, or breathing problems (such as sleep apnea, chronic obstructive pulmonary disease – COPD)
  • Have mental health problems
  • Have a personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol)
  • Have muscle weakness disorder (cataplexy)
  • Are an older adult as you may be more sensitive to the side effects of this drug

How to avoid Belsomra side effects

The best way to avoid side effects is to take Belsomra as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Belsomra recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Belsomra. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Belsomra as it can increase your risk of serious side effects, such as central nervous system depression, and increase your risk of falling.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Belsomra.

7. Monitor your weight

Belsomra may cause an increase in suicidal thoughts and behavior. If you experience these side effects while taking Belsomra, get medical advice from your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Belsomra.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Belsomra as needed.

Plenity side effects and how to avoid them

Plenity is an FDA-approved (U.S. Food and Drug Administration) medication manufactured by Gelesis. It is classified as a weight loss medication and is used to help with weight management in overweight adults. While Plenity is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Plenity include constipation and abdominal pain.

Learn more about the side effects of Plenity and what you can do to avoid them.

What is Plenity?

Plenity is a weight loss aid and weight management tool used with a healthy diet and exercise to treat obese adults with excess weight or obesity with a body mass index (BMI) of 25 to 40 kg/㎡.

Plenity weight loss pills contain superabsorbent hydrogel particles made of naturally derived building blocks, which absorb water once in the stomach. The gel particles mix with foods, creating a larger volume with higher elasticity and thickness in the stomach and small intestine, promoting satiety and fullness. The hydrogel is partially broken down by enzymes in the large intestine, losing most of its absorption ability. The released water is reabsorbed, with the cellulosic material excreted in the feces.

In clinical studies, 59% of Plenity responders had an average weight loss of 10% of their body weight in six months. Plenity is safe for people with or without other conditions such as hypertension, type 2 diabetes, or dyslipidemia.

Plenity dosage

Plenity is a prescription-only capsule available in the following doses: 0.75 grams.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Plenity side effects

In clinical trials (Gelesis Loss of Weight), there was no overall difference in side effects between the treatment and placebo groups. The most common gastrointestinal side effects were:

  • Diarrhea
  • Bloating
  • Nausea
  • Infrequent bowel movements
  • Constipation
  • Abdominal pain
  • Flatulence

Your doctor will assess the benefits of using Plenity against your risk of adverse events Patients are encouraged to report negative side effects or adverse reactions of Plenity to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

If you experience any of these side effects, seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Plenity cause headaches?

Headaches are not a side effect reported when using Plenity. Speak to your doctor for medical advice if you experience this side effect.

Plenity drug interactions

Other drugs may interact with Plenity, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your healthcare provider about your medications, including any supplements you are taking. Before taking Plenity, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Plenity warnings & precautions

You should not use Plenity if you:

  • Are allergic to the active ingredients carboxymethyl cellulose and citric acid
  • Have had an allergic reaction to gelatin, titanium dioxide, or any of the other ingredients in Plenity
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Plenity if you:

  • Are taking any of the medications that could interact with Plenity
  • Have active gastroesophageal reflux, peptic ulcer, or heartburn
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Plenity, to make sure it is safe for you.

How to avoid Plenity side effects

The best way to avoid side effects is to take Plenity as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Plenity recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Plenity. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Plenity, as it can increase your risk of dizziness, depression, and impaired judgment.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Plenity.

7. Know the signs and symptoms of Plenity side effects

Signs and symptoms of side effects include constipation, bloating, and abdominal pain. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Plenity.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Plenity as needed.

Evenity side effects and how to avoid them

Evenity is a brand-name medication manufactured by Amgen Inc. It is classified as a monoclonal antibody and is used to treat osteoporosis. While Evenity is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Evenity include muscle spasms. Less common but more serious side effects can include allergic reactions.

Learn more about the side effects of Evenity and what you can do to avoid them.

What is Evenity (romosozumab)?

Evenity contains the prescription medicine romosozumab. It is used for the treatment of postmenopausal women with osteoporosis (a condition where bones are weaker and more fragile) who are at high risk of bone fracture, classed as:

  • A history of osteoporotic fracture
  • Having multiple risk factors for fracture
  • Patients who are not tolerant to or have not responded to other treatments for osteoporosis

Evenity may be used alone or in combination with other medicines. It belongs to a class of drugs known as monoclonal antibodies. These are man-made proteins that behave like naturally occurring antibodies within your immune system.

Evenity blocks the action of sclerostin in the body. Sclerostin helps to control the production of bone in your body. Evenity helps to increase the production of bone and to a lesser degree, reduces bone resorption (the breakdown of bone into minerals such as calcium, which are transferred into the blood).

Romosozumab-aqqg has been shown in animal studies to stimulate new bone formation on trabecular and cortical bone surfaces by stimulating osteoblastic activity (the formation of bone). This results in an increase in trabecular and cortical bone mass and helps to improve bone structure and strength.

Does Evenity grow bone?

Evenity is used to treat women with osteoporosis after menopause at a high risk of fractures. Evenity reduces the risk of fractures risk by building new bone.

Evenity dosage

Evenity is available in injection form in the following doses: 105 mg/1.17 mL solution in a single-use prefilled syringe.

Evenity is given as an injection under the skin (subcutaneous) of your stomach, upper thigh, or upper arm. It is usually given as 2 injections, once a month for 12 months. Evenity should only be used for 12 monthly doses, as after this, its effects begin to reduce. Evenity is part of a treatment program that includes calcium and vitamin D supplements.

You are advised to brush your teeth on a regular basis while receiving Evenity. Tell your dentist you are receiving this medicine if you need dental work. Read the medication guide provided with this medicine for the drug and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Evenity side effects

The most common side effects of Evenity compared to placebo include:

  • Joint pain
  • Muscle spasms
  • Neck pain
  • Headaches
  • Injection site reactions

In rare instances, Evenity can cause more serious side effects. These can include:

  • Low calcium levels – muscle contractions or spasms, numb or tingly feeling around mouth, fingers, or toes
  • Swollen or red gums, infected gums, or loose teeth
  • Unusual or new pain in your thigh, hip, or groin
  • Osteonecrosis of the Jaw
  • Heart attack – chest pain, shortness of breath, feeling light-headed, dizziness
  • Stroke – headache, numbness, or weakness in the face, arm, or legs, problems talking, changes in vision, or loss of balance
  • Serious allergic reactions – hives, difficulty breathing, swelling of the face or throat, sore throat, burning eyes, red or purple skin rash

You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Evenity cause weight gain?

No. Weight gain is not a side effect of Evenity. Some women may have peripheral edema (swelling of the legs, ankles, or arms due to a build-up of fluid).

Does Evenity cause hair loss?

No, hair loss is not a side effect of Evenity.

Does Evenity cause dental problems?

Evenity may cause severe jaw bone problems. Speak to your healthcare provider or dentist about good dental healthcare while using this medication.

Does Evenity cause muscle pain?

Evenity may cause lower calcium blood levels. Symptoms of low calcium include muscle spasms, twitches, or cramps, numbness or a tingling sensation in your fingers, toes, or around the mouth.

Evenity drug interactions

Evenity can interact with other medications, including:

  • Steroid treatment – beclomethasone, cortisone, fludrocortisone, prednisolone
  • Bisphosphonates used to prevent bone breakdown – alendronate, ibandronate, pamidronate, risedronate
  • Treatments for cancer – axitinib, cabozantinib, everolimus, lenalidomide, pomalidomide
  • Other monoclonal antibodies for the reduction of bone loss – denosumab
  • Etelcalcetide – classed as an oligopeptide for the treatment of hyperparathyroidism in patients receiving hemodialysis treatment

Before taking Evenity, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Evenity warnings & precautions

You should not use Evenity if you:

  • Are allergic to the active ingredient romosozumab-aqqg
  • Have had an allergic reaction to any of the other ingredients in Evenity
  • Have low levels of calcium in your blood (hypocalcemia)
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Evenity if you:

  • Are taking any of the medications that could interact with Evenity
  • Have cancer
  • Are receiving chemotherapy
  • Have blood vessel disorders
  • Have had a stroke, heart attack, or any other heart problems
  • Are receiving dialysis or have kidney disease
  • Have dental problems
  • Are taking steroids
  • Cannot take calcium and vitamin D supplements daily

You should always check with your doctor or pharmacist before taking any medication, including Evenity, to make sure it is safe for you.

Evenity vs Prolia

Evenity and Prolia are both biologics but with different mechanisms of action. Prolia slows the breakdown of bone, while Evenity rebuilds bone. Evenity increases bone mineral density and reduces the risk of fractures, while Prolia raises bone mass.

Is Evenity worth the risk?

Evenity may increase your risk for heart attack, stroke, and death due to cardiovascular problems. Your doctor will decide if Evenity is safe for you to use.

How to avoid Evenity side effects

The best way to avoid side effects is to take Evenity as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Evenity recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Evenity. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Evenity.

6. Know the signs and symptoms of Evenity side effects

Signs and symptoms of side effects include neck pain and muscle spasms. If you experience these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Evenity.

8. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Evenity as needed.

What this means for you

If you are at risk of osteoporosis and are postmenopause, Evenity can help you. Be sure to tell your healthcare provider your medical history to ensure Evenity is for you.

Forteo side effects and how to avoid them

Forteo is a brand-name medication that is manufactured by Eli Lilly and Company. It is classified as a parathyroid hormone (PTH) analog, which means it works like PTH your body makes naturally and is used to treat osteoporosis (bone loss). While Forteo is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Forteo include leg cramps and joint pain. Less common but more serious side effects can include severe allergic reactions.

Learn more about the side effects of Forteo and what you can do to avoid them.

What is Forteo (teriparatide)?

Forteo is a medication prescribed to adults to treat osteoporosis. Specifically, it’s given to:

  • Postmenopausal women with osteoporosis who have a high risk of bone fractures
  • Men with primary osteoporosis or hypogonadal osteoporosis who have a high risk of bone fractures
  • Men and women with osteoporosis caused by glucocorticoid medicines, like prednisone, who have a high risk of bone fractures

Osteoporosis can be treated with a range of medications, but most treatments only prevent you from losing more bone mass. Forteo can go a step further and help you rebuild lost bone. It can help increase your bone mineral density, giving you harder bones that are less likely to fracture.

The active ingredient in Forteo is called teriparatide. It’s a hormone your body naturally produces that promotes bone growth. When you take Forteo, the teriparatide it contains encourages your body to make more calcium and phosphate available for bone production. It also stimulates two types of cells, called osteoblasts and osteoclasts, that help produce new bone material increasing your bone density and strength.

Forteo dosage

Forteo is available in injection form in the following doses: 250 mcg/mL in single-use prefilled pens containing daily doses of 20 mcg.

Forteo is injected under your skin (subcutaneous injection) using a self-injecting, pre-filled Forteo delivery device. Your doctor may prescribe additional calcium and vitamin D supplements to help your bones get stronger.

You are advised to read the prescribing information and medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Forteo side effects

The most common side effects of Forteo include:

  • Injection site reactions
  • Nausea
  • Leg cramps
  • Joint pain

In rare instances, you could experience more serious long-term side effects. These can include:

  • Severe allergic reactions – chest pain, discomfort, tightness, trouble breathing, or heaviness
  • A fall in blood pressure (hypotension) when you change positions that can cause dizziness, lightheadedness, a fast heartbeat, and fainting
  • Increased risk of osteosarcoma (a type of bone cancer)
  • An increase in blood calcium levels (hypercalcemia) – nausea, vomiting, constipation, tiredness, and muscle weakness

If you experience any of these serious side effects, stop taking Forteo and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Forteo cause weight gain?

Weight gain or weight loss is not a side effect of using Forteo. Speak to your doctor if you experience this side effect.

Does Forteo cause hair loss?

Hair loss is not a side effect of Forteo. Speak to your doctor for medical advice if you experience this side effect.

Does Forteo cause cancer?

Bone cancer has been seen in animal studies with rats and rarely in humans. Speak to your doctor immediately if you experience bone pain, a tender lump or any other swelling under the skin.

Can Forteo cause kidney damage?

Forteo may cause an increase in calcium levels in the blood. High calcium loss through the kidneys may cause kidney stones.

How long do Forteo side effects last?

Common side effects such as dizziness or a fast heartbeat may continue for a few minutes to a couple of hours. This side effect may go away as your body adjusts to Forteo.

Forteo drug interactions

Forteo can interact with other medications, including:

  • Medications that contain digoxin which can change how Forteo and the other medications work

Before taking Forteo, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Forteo warnings & precautions

Don’t take Forteo if you:

  • Are allergic to the active ingredient teriparatide or any of the other ingredients in Forteo
  • Have already taken Forteo for over two years (you shouldn’t take Forteo for more than two years over your lifetime)
  • Are under 18 years of age

Talk to your doctor before you use Forteo if you:

  • Have a bone disease, like Paget’s disease
  • Have any type of bone cancer
  • Are a young adult and your bones are still growing
  • Have, or have had kidney stones
  • Have, or have had, too much calcium in your blood
  • Have had radiation therapy
  • Will have problems injecting yourself and don’t have someone who can help you
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Forteo, to make sure it is safe for you.

What happens when you stop taking Forteo?

Once treatment is stopped with Forteo, any gains in bone density will be lost. You may be prescribed treatments such as Fosamax after stopping treatment with Forteo from maintaining your bone mineral density.

How to avoid Forteo side effects

The best way to avoid side effects is to take Forteo as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Forteo that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Forteo. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is not likely to interact with teriparatide or parathyroid hormone. High alcohol consumption is, however, a known risk factor for osteoporosis. Moderate alcohol consumption is advised when being treated for osteoporosis.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience problems with your feet while taking Forteo.

7. Know the signs and symptoms of Forteo side effects

Signs and symptoms of side effects include leg cramps and joint pain. If you experience these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Forteo.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Forteo as needed.

Basaglar side effects and how to avoid them

Basaglar is a brand-name insulin product manufactured by Eli Lilly and Company. It is classified as a biological medication used to manage hyperglycemia (high blood sugar levels) in adults and pediatric patients aged 6 years and older. While Basaglar is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Basaglar include hypoglycemia and injection site reactions. Less common but more serious side effects can include life-threatening allergic reactions.

Learn more about the side effects of Basaglar and what you can do to avoid them.

What is Basaglar (insulin glargine)?

Basaglar KwikPen (insulin glargine) is an FDA (Food and Drug Administration)-approved long-acting type of insulin used with diet and exercise to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and adults with type 2 diabetes mellitus.

How does Basaglar KwikPen work?

Basaglar KwikPen (insulin glargine) is a biological medication that works similarly to human insulin (endogenous) made by your body. The main action of insulin, including the long-acting insulin Basaglar KwikPen, is to control blood glucose levels. It does this by promoting the uptake of glucose into muscle and adipose tissue (fat) and preventing glucose production in your liver. Insulin also inhibits the breakdown of fat (lipolysis) and protein (proteolysis).

Basaglar dosage

Basaglar is available in injection form as Basaglar KwikPen and Basaglar Tempo PenTM. Toujeo contains 3 times as much insulin per mL than the Basaglar brand.

Basaglar is given as a subcutaneous injection under the skin once daily at the same time. Do not inject Basaglar into a vein or a muscle, and do not inject into the same place two times in a row.

You are advised to read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Basaglar side effects

The most common possible side effects of Basaglar include:

  • Hypoglycemia (low blood sugar) – shakiness, fast heartbeat, hunger, headaches, confusion, lightheadedness, numbness, or tingling of tongue, lips, or fingers
  • Injection site reactions
  • Skin rash
  • Weight gain
  • Edema
  • Loss of fat tissue (lipodystrophy)

Basaglar KwikPen can sometimes cause serious side effects, including:

  • Life-threatening hypersensitivity reactions, including hives, angioedema, and trouble breathing
  • Hypokalemia (low potassium levels) – leg cramps, irregular heartbeats, increased thirst or urination, kidney problems, muscle weakness

If you experience any of these serious side effects, stop taking Basaglar and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Basaglar make you gain weight?

Yes, Basaglar may cause weight gain as a side effect. Speak to your doctor for medical advice if you experience this side effect.

Does Basaglar make you tired?

Basaglar may cause symptoms of low blood sugar, including dizziness, sweating, and tiredness.

Does Basaglar cause diarrhea?

Yes. You may experience diarrhea as a side effect when using Basaglar. Speak to your healthcare provider for medical advice if you experience this side effect.

Basaglar drug interactions

When Basaglar KwikPen is taken with other drugs, they may change Basaglar’s glucose-lowering effect or increase the frequency and severity of side effects. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take. Some major drug interactions with Basaglar KwikPen include:

  • Other diabetic medications
  • ACE inhibitors
  • Sulfonamide antibiotics
  • Atypical antipsychotics
  • Estrogens, progesterones, and oral contraceptives
  • Thyroid hormones
  • Beta-blockers
  • Diuretics
  • Corticosteroids
  • Monoamine oxidase inhibitors (MAOIs)
  • Glucagen (glucagon)

Is 20 units of Basaglar a lot?

No, A child weighing about 44 pounds (lbs) will use 8 to 20 units each day. One-third of this would be long-acting insulin (Basaglar), meaning the dosage of Basaglar would be 2 to 7 units once daily. Doses are based on body weight and will naturally be higher for adults.

Basaglar contraindications

Basaglar KwikPen should not be taken if you have had an allergic reaction to its active ingredient, its excipients, or other insulin glargine products. It is also contraindicated in patients who are having episodes of hypoglycemia (low blood sugar level) or diabetic ketoacidosis. Also:

  • Never share your Basaglar KwikPen, needles, or syringes
  • The risk of hypoglycemia, including severe hypoglycemia, is increased with changes to your insulin dose, insulin regimen, diet, or physical activity. Make sure you are familiar with the symptoms of hypoglycemia, such as tremors, nervousness, increased heartbeat, sweating, confusion, fatigue, and hunger
  • Severe allergic reactions have occurred with Basaglar KwikPen. Discontinue Basaglar KwikPen immediately and seek medical assistance if you have any signs of anaphylaxis
  • Increased risk of fluid retention, edema, and heart failure when Basaglar KwikPen is used with thiazolidinediones (TZDs) such as Actos (pioglitazone)
  • It is not known if Basaglar is safe to use during pregnancy or while breastfeeding

Basaglar vs Lantus side effects

Basaglar and Lantus both contain insulin glargine, a long-acting insulin used to help manage blood sugar levels in type 1 and type 2 diabetes. Both are given as once-daily injections under the skin. Basaglar is not considered to be biosimilar to Lantus due to different manufacturing processes, but the two drugs do have similar side effects.

How to avoid Basaglar side effects

The best way to avoid side effects is to take Basaglar as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Basaglar recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Basaglar. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Basaglar, as it can make managing your blood sugar levels more difficult, increasing the risk of hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Basaglar.

7. Know the signs and symptoms of Basaglar side effects

Signs and symptoms of side effects include hypoglycemia and injection site reactions. If you experience these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Basaglar may cause weight gain. If you experience this side effect while taking Basaglar, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Basaglar.

10. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Basaglar as needed.

Saxenda alternatives for weight loss

Saxenda is an FDA-approved (U.S. Food and Drug Administration) brand-name medication manufactured by Novo Nordisk Inc. It is classed as a glucagon-like peptide-1 receptor agonist and has been used to treat diabetes, and is FDA-approved for weight loss.

Learn more about Saxenda, what it’s used for, its side effects, interactions, the precautions you should take when using it, and the alternative treatments available.

What is Saxenda?

Saxenda contains liraglutide as the active ingredient. Liraglutide is similar to a naturally occurring hormone that controls digestion, insulin levels, and blood glucose levels. Saxenda is recommended alongside a reduced-calorie diet and an increase in exercise. It is used to help manage obesity in adult patients with a body mass index (BMI) of:

  • 30 kg/m2 or more, or
  • 27 kg/m2 or more with a weight-related condition such as high blood pressure, type 2 diabetes, high cholesterol, triglycerides, or a low HDL cholesterol level that is making plaque build-up in your arteries worse

Saxenda is not specifically for the treatment of type 1 or type 2 diabetes or weight loss. Saxenda is part of a treatment plan that will include diet, exercise, and weight management. GLP-1 is classed as a physiological regulator of appetite and calorie intake. This means it works by a method known as negative feedback.

RELATED: What is Saxenda

Is Saxenda an appetite suppressant?

Saxenda works by suppressing your appetite by increasing the feeling of being full and reducing the sense of hunger in your brain. This leads to a reduction in eating and consuming fewer calories and losing weight.

Does Saxenda help with diabetes?

Yes, when Saxenda is used in combination with diet and exercise, it has been shown to be effective in preventing the development of type 2 diabetes.

What are the side effects of Saxenda?

The most common side effects of Saxenda in clinical trials include:

  • Gastrointestinal side effects – indigestion, nausea, vomiting, abdominal pain, diarrhea, constipation
  • Injection site reactions
  • Fast heart rate
  • Tiredness
  • Headaches and dizziness

More serious side effects of Saxenda include:

  • Increased heart rate
  • Suicidal thoughts or sudden changes in behavior and mood
  • Severe nausea, vomiting, or diarrhea that will not stop
  • Hypoglycemia (very low blood sugar levels) – feeling very weak, shaking, confused, sweating, fainting, or seizures
  • Pain or difficulty urinating, swelling in ankles or feet, tiredness, and difficulty breathing
  • Trouble swallowing, lump, or swollen neck
  • Jaundice – yellowing of eyes or skin, darker stools, upper stomach pain spreading to the back
  • Increased risk of thyroid cancer or tumors
  • Pancreatitis (inflammation of the pancreas)

You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Saxenda dosage

Saxenda is available in injection form at 6 mg/mL and delivers the following doses: 0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg or 3 mg.

Liraglutide is classed as an acylated human glucagon-like peptide-1/GLP-1 receptor agonist. Liraglutide binds to and activates the GLP-1 receptor. Unlike naturally occurring GLP-1 in the body, which has a half-life of up to 2 minutes, liraglutide is stable against breakdown by enzymes in the body and has a half-life of 13 hours.

Saxenda is given as a subcutaneous injection under the skin. It can be given at any time of the day, with or without a meal. You should not inject it into the same place two times in a row.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: Saxenda Dosage

What medication is similar to Saxenda?

Medications similar to Saxenda include:

These medications contain active ingredients that belong to the same class of drugs (glucagon-like peptide-1 receptor agonist) as the active ingredient in Saxenda.

Natural alternative to Saxenda

Natural alternatives to Saxenda for weight loss that are safe and proven to be effective will involve changes to your lifestyle. This will include having a healthy diet and maintaining a good level of physical activity. Both of these will help with weight loss and are especially beneficial if you are suffering from obesity. Speak to your healthcare provider or a dietitian for advice on what foods to eat and which to avoid.

Supplements are another natural alternative that may have beneficial effects for the purposes of weight loss. This, however, needs further investigation as the results of using supplements to aid weight loss are not conclusive.

Wegovy vs Saxenda

Wegovy is also an FDA-approved weight loss medication manufactured by Novo Nordisk and is also a glucagon-like peptide-1 receptor agonist indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients.

The active ingredient in Wegovy, semaglutide, acts in the same way as GLP-1 incretin hormones. By stimulating the same receptors, it causes your body to release more insulin and less glucagon and digest food slower.

Wegovy is available in a prefilled injection form in the following doses: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, or 2.4 mg. Wegovy should be injected subcutaneously once weekly, on the same day each week, at any time of day, with or without meals, due to its 7-day elimination half-life.

As Wegovy and Saxenda belong to the same class of drugs, their side effects, drug interactions, and warnings and precautions are the same.

RELATED: Wegovy vs Saxenda

What is better than Saxenda for weight loss?

Wegovy injections have been found to be more effective for weight loss than Saxenda. A 2018 study carried out over a year compared weight loss with semaglutide injections, liraglutide injections, and placebo. Participants received daily doses of semaglutide, liraglutide, or a placebo injection. Semaglutide was given in daily doses rather than weekly doses in this trial. At week 52, the average weight loss with those given semaglutide injections was 11.2-13.8% of their starting body weight, whereas liraglutide participants lost around 7-8%.

Wegovy produces better weight loss and cardiovascular outcomes, but it is important to know that this shouldn’t be your only deciding factor when choosing between medications. The final decision on your treatment is down to your prescriber, alongside a discussion with you. Both medicines work in a very similar way within the body, but you should seek medical advice from your healthcare professional about which of these weight loss drugs would be best for you based on your medical conditions and your current medication, including any over-the-counter meds and supplements.

What is the difference between Saxenda and Victoza?

Saxenda and Victoza are both injectable medications containing liraglutide. Both are available in similar, pre-filled, multi-dose pens that deliver doses of 0.6 mg, 1.2 mg, and 1.8 mg. Saxenda is also available in pre-filled, multi-dose pens that deliver doses of 2.4 mg or 3 mg. The only difference between these two medications is the conditions they are approved to be used for by the FDA. Saxenda is used in combination with a reduced-calorie diet and increased physical activity for chronic weight management, while Victoza is used in combination with diet and exercise to improve glycemic control in patients 10 years of age and older with type 2 diabetes or to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes with cardiovascular disease.

RELATED: Saxenda vs Victoza

Is there a cheaper alternative to Saxenda?

Ozempic is the cheapest alternative to Saxenda. The average monthly cost for Ozempic is around $700, while the average monthly cost for Saxenda when you first start using it is around $1000 (your dose of Saxenda will increase as you use it, and so will your monthly cost). Currently, however, Ozempic is not FDA-approved for weight loss, but you may lose weight when using it to treat type 2 diabetes. Ozempic is under review to be used for weight loss in combination with exercise and diet.

RELATED: Saxenda vs Ozempic

How do you get Saxenda at an affordable price?

Saxenda prices without insurance will vary depending on how much you buy and where you buy it. The cost of Saxenda with insurance will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

Is there a generic version of Saxenda?

Unfortunately, Saxenda is only available as a brand-name medication. It’s not available in a generic form.

Saxenda drug interactions

Saxenda can interact with other medications. This can change how Saxenda and other medications work and make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Saxenda may interact with other medications, such as antibiotics, and other diabetic treatments, such as insulin or sulfonylureas, antivirals, diuretics, and corticosteroids.

Saxenda warnings & precautions

You should not use Saxenda if you:

  • Are allergic to the active ingredient liraglutide
  • Have had an allergic reaction to any of the other ingredients in Saxenda
  • Are using insulin or albiglutide, dulaglutide, or exenatide
  • Have multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Have a family history of medullary thyroid carcinoma
  • Have diabetic ketoacidosis
  • Are under 18 years of age

Talk to your doctor before using Saxenda if you:

  • Are taking any of the medications that could interact with Saxenda
  • Have kidney disease
  • Have liver disease
  • Have high cholesterol or triglycerides
  • Have heart problems
  • Have problems with your pancreas or gallbladder
  • Have depression or suicidal thoughts
  • Have stomach or digestion problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Saxenda, to make sure it is safe for you.

Is it safe to take Saxenda if I am pregnant?

Saxenda is not recommended for use during pregnancy, and if a patient is planning to become pregnant, treatment with Saxenda should be stopped because weight loss is of no benefit to a pregnant woman and may cause fetal harm.

Janumet alternatives for diabetes

Janumet and Janumet XR are brand-name diabetes medications manufactured by Merck Sharp & Dohme Corp. It is used to help manage blood sugar levels in adults who have type 2 diabetes mellitus. Janumet should be used alongside exercise and changes to your diet.

Here, we will take a look at what Janumet is, how it works, its side effects, and the alternative treatments available to Janumet for the treatment of type 2 diabetes.

How does Janumet work?

Janumet contains two active ingredients, called sitagliptin and metformin. These active ingredients reduce the amount of sugar released into your blood and increase the insulin produced by your pancreas. Janumet helps you lower your blood glucose levels.

Sitagliptin belongs to the drug class known as dipeptidyl peptidase-4/DPP-4 inhibitors, which increases the amount of insulin you produce after you’ve eaten. When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP that make your pancreas secrete insulin. As you continue to digest your food, these digestive hormones are broken down by an enzyme called DPP-4. This allows your levels of insulin to fall again. If you take Janumet, sitagliptin stops the DPP-4 enzyme from breaking down these digestive hormones. This keeps the hormones active for longer and makes you produce more insulin.

Metformin is classed as a biguanide and reduces how much sugar your liver releases into your blood. As your digestive system breaks down food, your liver releases sugar into your blood. If you take Janumet, metformin slows down the process that causes your liver to do this, lowering the amount of sugar released.

What are the side effects of Janumet?

The most common side effects caused by Janumet in clinical trials include:

  • Headaches
  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Upper respiratory infections
  • Hypoglycemia (low blood sugar)

In rare instances, Janumet can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • Lactic acidosis – a buildup of lactic acid in your body that can cause breathing difficulties, malaise, sleepiness, muscle pain, and stomach pain
  • Severe joint pain (arthralgia)
  • Inflammation of the pancreas (pancreatitis)
  • Kidney failure

If you experience any of these serious side effects, stop taking Janumet and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Janumet drug interactions

Janumet can interact with other medications, including carbonic anhydrase inhibitors (such as zonisamide, acetazolamide, or dichlorphenamide), cationic drugs (such as amiloride, digoxin, morphine, or vancomycin, diuretics, corticosteroids, estrogens, oral contraceptives, nicotinic acid, and calcium channel blocking drugs.

Before taking Janumet, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Janumet warnings & precautions

Janumet isn’t suitable for everyone. Don’t take Janumet if you:

  • Are allergic to the active ingredients sitagliptin or metformin
  • Are allergic to any of the other ingredients in Janumet (listed in the leaflet which comes with the medication)
  • Have type 1 diabetes (Janumet is for type 2 diabetes)
  • Have reduced kidney function
  • Have diabetic ketoacidosis – a potentially life-threatening condition caused by diabetes where you break down body fat too quickly
  • Are under 18 years of age

Talk to your physician before taking Janumet if you:

  • Are taking any of the medications that could interact with Janumet (listed in the section above)
  • Have a history of pancreatitis
  • Have heart problems, including congestive heart failure
  • Have liver disease
  • Have kidney disease
  • Are going to get an injection of dye or contrast agents for an x-ray
  • Drink alcohol often or binge drink alcohol
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age

Is there a cheaper alternative to Janumet?

Janumet prices will vary depending on how much you buy and where you buy your medication from. As a guide, a pack of 60 Janumet tablets will cost around $650. Alternative brand name medications containing similar classes of drugs include:

How much these cost and whether they are cheaper than Janumet will also depend on how much you buy and where you buy them from.

Generic (non-branded) medications are normally a cheaper alternative to branded medications such as Janumet. Examples of these include drugs such as metformin, glipizide, and glyburide. Again, how much you pay for these drugs will vary depending on how much you buy and where you buy it from.

Cheaper alternatives to Janumet may also include using natural alternatives. A healthy, well-balanced diet and exercise can help with weight loss and the management of blood sugar levels in patients with diabetes.

Supplements such as cinnamon have been shown to help with the management of Type 2 diabetes. Herbal or plant-based alternatives such as berberine or turmeric are also natural alternative treatments. Speak to your healthcare provider for medical advice before taking supplements to make sure they are safe to take.

Other alternatives to Janumet

What drug can be substituted for Januvia?

Alternatives to Januvia include medications such as Micronase (glyburide), Rybelsus (semaglutide), Jardiance (empagliflozin), Onglyza (saxagliptin), Nesina (alogliptin), and Janumet (sitagliptin/metformin). Your healthcare provider will decide which alternatives are suitable for you based on your medical condition.

Which is better Janumet or Januvia?

Januvia contains sitagliptin only, while Janumet contains sitagliptin and metformin. Januvia is only able to stimulate the body to produce more insulin, while Janumet is able to do this as well as reduce the amount of glucose produced by the liver and reduce the absorption of glucose back into the body.

Are Jardiance and Janumet the same thing?

No. Jardiance contains empagliflozin, which is classed as a sodium-glucose co-transporter 2 (SGLT2), as the active ingredient. Janumet contains sitagliptin and metformin.

Your kidneys normally help you recycle sugar back into your blood from your urine with the help of a protein called SGLT-2. Empagliflozin blocks this protein from working, reducing how much sugar your kidneys recycle. This makes you lose more sugar in your urine. This diuretic action of Jardiance can help to reduce blood pressure.

Jardiance is prescribed to adults with type 2 diabetes to reduce blood sugar levels when used alongside exercise and diet changes and to reduce risk factors such as death by cardiovascular/heart disease.

What’s the difference between Janumet and metformin?

Janumet contains the active ingredients sitagliptin and metformin. This gives Janumet the ability to not only work as metformin does but also allows it the additional function of sitagliptin. Metformin is only able to reduce how much sugar your liver releases into your blood, while Janumet is also able to increase the amount of insulin released from the pancreas and keep the insulin working longer.

Is there a Janumet generic?

Janumet is only available as a brand-name medication. It is not currently available in a generic form. Sitagliptin and metformin, the active ingredients in Janumet, are available separately as generic medications.

When will generic Janumet be available?

Generic Janumet will not be available until the patent for Janumet expires in May 2027. A patent gives the manufacturers of Janumet the exclusive right not to allow a competitor to make a cheaper version of Janumet.

What is Victoza?

Victoza is a glucagon-like peptide-1 (GLP-1) receptor agonist whose active ingredient is liraglutide. It was approved in 2010 by the U.S. Food and Drug Administration (FDA) along with a healthy diet and exercise to lower blood sugar levels in patients 10 years of age and older with type 2 diabetes. It is used to reduce heart attacks and stroke in type 2 diabetic patients with heart disease.

Advair alternatives for asthma and COPD

Advair is an FDA-approved brand-name medication manufactured by GSK (GlaxoSmithKline). It contains an anti-inflammatory medicine (fluticasone propionate) and a long-acting bronchodilator (salmeterol) and is used to prevent asthma attacks and flare-ups or worsening of chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis or emphysema.

Advair is an expensive brand-name medication with several alternatives available, including medications with lower-cost generic alternatives. Learn more about what Advair Diskus is, how it works, its side effects, and alternatives for Advair.

What is Advair (fluticasone/salmeterol)?

Advair is a prescription medication used for the maintenance treatment of asthma in adults and children 12 years of age and older. Advair HFA is a metered-dose inhaler that contains the fluticasone propionate/salmeterol combination. When inhaled, these ingredients work together to open up your lungs and airways. Fluticasone propionate is a type of corticosteroid. When you inhale Advair, molecules of fluticasone propionate attach to areas on the surface of the cells in your airways and lungs called glucocorticoid receptors. This stimulates the receptors, producing lower amounts of the substances that trigger inflammation and greater amounts of anti-inflammatory proteins. This helps to reduce inflammation throughout your lungs and airways.

Salmeterol is classed as a long-acting beta 2-adrenergic agonist (LABA). It attaches to areas outside of muscle tissue in your airways and lungs called beta-2 receptors. This stimulates the receptors, causing them to relax the muscle tissue, opening up your lungs and airways, and allowing you to breathe more easily.

What are the most common side effects of Advair?

The most common side effects of Advair in clinical trials include:

  • Headaches, dizziness, nausea, vomiting
  • Sore throat, hoarseness and changes to your voice
  • An increase in upper respiratory tract infections
  • Sinus and throat infections

More serious side effects of Advair include

  • A weakened immune system, makes you more vulnerable to infections, including serious infections like tuberculosis
  • Adrenal insufficiency
  • Life-threatening allergic reactions, such as hives, swelling in your face, mouth, and throat, can make it difficult to breathe and cause shortness of breath
  • A sudden worsening of your asthma symptoms, including asthma attacks (paradoxical bronchospasm)
  • Fungal infections (candida/thrush) in your mouth and throat – this is less likely if you rinse your mouth out with water after taking your Advair Diskus
  • Increased blood pressure
  • A fast and/or irregular heartbeat
  • A thinning and weakening of bones (osteoporosis)
  • An increased risk of eye problems, including glaucoma, cataracts, and blurred vision
  • An increased risk of developing pneumonia if you also have chronic obstructive pulmonary disease (COPD)
  • Slowed rates of growth in children

These aren’t all the possible side effects Advair can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to a healthcare professional. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Alternative to Advair Diskus

Alternatives to Advair Diskus inhalation powder include a range of alternative aerosol asthma inhalers and oral medications. Oral tablets include tablets such as Singulair (montelukast). Alternative inhalers include:

What inhaler is comparable to Advair?

Symbicort (budesonide/formoterol), Dulera (mometasone/formoterol), and Breo (fluticasone/vilanterol) are combination inhalers similar to Advair. These medications all contain an inhaled corticosteroid (ICS) and a long-acting beta-agonist (LABA).

What is the generic equivalent of Advair?

Wixela Inhub is the first approved generic version of Advair in the United States. It is a therapeutically equivalent medication to Advair Diskus that is manufactured by Mylan Pharmaceuticals.

RELATED: Wixela vs Advair

What are the problems with generic Advair?

A generic version of Advair Diskus has recently become available. It is marketed under the name Wixela Inhub. This generic version is similar to Advair. A generic drug must, by law, contain the same active ingredients as the branded version and work in the same way. In this case, the generic versions’ design and doses are different from Advair, meaning that those with a prescription for Advair must obtain a new prescription for the generic inhaler if they wish to switch to the generic.

What are the cheapest steroid inhalers?

Steroid inhalers will vary in cost depending on how many you buy and where you buy them from. The cheapest steroid inhaler, Breo Ellipta (budesonide/glycopyrrolate/formoterol fumarate) will cost around $180 for 1 inhaler of 28 blisters of 100 mcg/25 mcg. Arnuity Ellipta (fluticasone furoate) and Asmanex HFA (mometasone furoate) will cost around $260 for 1 inhaler. Qvar Redihaler (beclomethasone/dipropionate HFA) and Flovent HFA (fluticasone) will cost around $360 for 1 inhaler, and the most expensive, Symbicort (budesonide/formoterol) and Advair HFA (fluticasone propionate/salmeterol) will cost over $500 for 1 inhaler.

Natural alternatives to Advair

Natural alternatives for asthma treatment are sometimes used by patients to help protect themselves from the causes of asthma attacks. However, it is important to understand that natural alternative remedies are not as effective as using asthma medication.

  • Herbs and supplements may help with some of the symptoms of asthma, but research in this area is ongoing and not conclusive. Natural herbs may include ginkgo, dried ivy, black seed, choline, and French maritime pine bark extract. Some natural alternatives and over-the-counter treatments have been found to cause serious side effects
  • Magnesium and fish oil in combination with Vitamin C may reduce inflammation and reduce asthma symptoms
  • Caffeine, a natural bronchodilator
  • Reducing stress can reduce the symptoms of asthma. In children, this may involve breathing exercises and relaxation
  • Yoga and relaxation to help properly control breathing and reduce stress
  • Acupuncture – placing very thin needles at specific points on the body to ease the symptoms of asthma

Speak to your healthcare provider for medical advice before trying any new alternative treatments for asthma.

State of Emergency

Which US States have the Highest Number of Emergency Room Visits?

It has been reported that over 130 million Americans visit US emergency rooms each year. The ongoing effects of the COVID-19 pandemic have led to more and more state residents being treated in emergency rooms. Elderly people in particular have suffered from falling ill with the virus, which has caused a surge in hospital discharges.

Here at NiceRx, we felt it was important to address the increase in hospital visits in recent years within the US. The states that were hit the most by the COVID-19 virus tended to see a higher number of people visiting the emergency department, which has caused issues with waiting lists and resources.

In this report, we reveal the US states with the higher number of emergency room visits and the most common reasons for hospital discharges. We also explore which hospitals in the US had the most emergency room visits.

With emergency departments in high demand, we included expert tips on the injuries and illnesses which require emergency treatment and those that are less of a priority.

Before we commence the State of Emergency in the US, here at NiceRx, we work with your healthcare provider to help you access affordable medications directly from US pharmaceutical companies, including popular brand-name medications like Entresto.

States with the Most Emergency Room Visits

We will now explore the states with the highest number of emergency room visits. Our figures are based on medical data, which included all adults who are expected, payers. Most of the data is from 2020, and any states with no data available were removed.

 

States with the most emergency room visits

 

1. New York

ED Visits per 10,000 Residents: 2,283 visits

New York had the highest number of emergency room visits on our data set, with the figures collected from 2019. The state had a total of over 1.9 million visits in 2019, a total of 2,283 per 10,000 residents.

In New York state, over four million people make approximately seven million visits to hospital emergency departments that often do not result in a hospital stay. The primary reason for ED visits shows that many could have avoided a hospital stay, in a less costly or preventive care setting.

 

2. Mississippi

ED Visits per 10,000 Residents: 1,480 visits

Mississippi had the second-highest number of emergency room visits in 2020, with a total of 441,300 discharges. That’s a total of 1,480 visits per 10,000 residents.

Research revealed that rural Mississippians were more likely to use emergency rooms for COVID-19 visits than their urban counterparts, making up 64% of total ER visits in Mississippi during the 15-month period. It’s likely due to a lack of healthcare systems in the state’s remote areas.

3. Florida

ED Visits per 10,000 Residents: 1,293 visits

Florida had the third-highest number of emergency room visits in 2020, with a total of 2,742,700 discharges. That’s a total of 1,293 visits per 10,000 residents.

In 2020, it was found that the number of ER visits in Florida between March and April decreased by 42% compared to the previous year, according to the federal Centers for Disease Control and Prevention. However, the number of visits for infectious-disease screenings and exposures increased fourfold.

States with the Fewest Emergency Room Visits

We will now take a look at the states with the lowest emergency visit numbers in the US in the last quarter of 2020.  We found that the states with the lowest numbers were geographically diverse and tended to be smaller state populations.

 

States with the fewest emergency room visits

 

1. Hawaii

ED Visits per 10,000 Residents: 342 visits

Hawaii had by far the lowest emergency department visits out of all of our states. The data set, from 2016, showed that just 127,150 visits were recorded in quarter 4 of the year. That’s 342 visits per 10,000 Hawaii residents.

Just this year, it was reported that Mau’s private hospital had suffered from budget shortfalls, and the hospitals faced staff shortages. These issues have hampered hospital performance in the state, along with a series of cuts caused by the pandemic.

 

2. Maryland

ED Visits per 10,000 Residents: 554 visits

Maryland was the state with the second-lowest number of emergency department visits. The data from the last quarter of 2020 revealed that there were 334,450 emergency room visits, just 554 per 10,000 Maryland residents.

Maryland undertook an expanded testing and tracing scheme, increased hospital surge capacity, and ramped up its supply of PPE, as well as a robust contact tracing operation. The state managed to take early, aggressive measures to slow the spread of COVID-19.

 

3. New Jersey

ED Visits per 10,000 Residents: 556 visits

New Jersey was the state with the third lowest number of emergency department visits. The data from the last quarter of 2020 showed that there were a total of 493,750 discharges, just 556 visits per 10,000 New Jersey residents.

New Jersey’s Department of Health set the standard for the public to visit COVID-19 testing locations across the state, rather than visiting the emergency department. The state’s health commissioner relayed that emergency departments are only for those who need critical, life-saving care.

 

The Most Common Illnesses for Emergency Room Visits in the US

To further tackle the state of emergency in the US, we will now look into state-specific monthly emergency room patient stays related to COVID-19 and other conditions. This data is based on the December 2021 state inpatient databases (SID), however, some state data was collected for different dates (see the last table). Any states without relevant data were removed.

 

Most common illnesses for emergency room visits in the US

1. Maternal and Neonatal Conditions

Total Discharges: 519,500

The most common reason for patients visiting the emergency room in the last quarter of 2020 was for maternal and neonatal conditions, with a total of 519,500 discharges collected in December 2021.

The neonatal period is a vulnerable period of pediatric health. Emergencies typically occur during this period, although many emergency care visits are sometimes preventable with preventive hospital care in the newborn period. Patients visiting the ER with a non-emergency can lead to increased costs and loss of resources in healthcare.

 

2. Surgeries

Total Discharges: 412,800

Surgeries were the second most common reason for patients to visit the emergency room in the last quarter of 2020. In December 2021, there were a total of 412,800 hospital visits within the month.

The most common surgical emergencies which require an inpatient stay in the emergency room are acute appendicitis, bowel obstruction, gastrointestinal perforation, intestinal volvulus, acute mesenteric ischemia, peritonitis, and stercoral perforation.

 

3. COVID-19

Total Discharges: 197,500

The COVID-19 virus was the third most common illness for patients to visit the emergency room in the last quarter of 2020. There were a total of 197,500 monthly visits in the last quarter of 2020 in the US.

 

Most common illnesses for emergency rooms visits in the US

 

There was a significant decline in emergency room visits during the outbreak period of COVID-19. However, the number of emergency room visits remained stable during the pandemic and towards the end of 2021. Changes may have resulted from public fear of the virus and may be down to the delay of medical intervention.

 

Least common illnesses for emergency room visits in the US

 

We will now look at the least common illnesses for emergency room visits in the US within the last quarter of 2021.

1. Influenza

Total Discharges: 4,500

Influenza was the least common illness for emergency room visits in the US within the last quarter of 2021. There were a total of just 4,500 visits recorded in December 2021 across the US.

More commonly known as the flu, influenza has become one of the main drivers of increased winter mortality. Seasonal influenza epidemic periods have been associated with an increase in emergency department visits across the country.

 

2. Injuries

Total Discharges: 103,300

Injuries were the second least common cause of emergency room visits in the US within the last quarter of 2021. There were a total of just 103,300 visits recorded in December 2021 across the US.

 

3. Mental Health and Substance Use Disorders

Total Discharges: 116,300

Mental health and substance use disorders were the third least common reason for emergency room visits in the US during the last quarter of 2021. There were a total of just 116,300 visits recorded in December 2021.

Research revealed this year that emergency department psychiatric visit rates consistently increased, before and during the pandemic among young people and the middle age group.

US Hospitals with the Most Emergency Room Visits, Ranked

We will now explore which US hospitals had the most emergency room visits in 2021. We collected our data from Becker’s Hospital Review, where the figures were self-reported by individual hospitals.

 

US hospitals with the most emergency room visits

 

 

All US hospitals with the most emergency room visits

 

1. Parkland Health and Hospital System (Dallas)

Emergency Room Visits in 2021: 210,152*

Parkland Health and Hospital System in Dallas reported the most emergency room visits in 2021. In 2021, research revealed that hospitals in North Texas saw an expected rise in hospitalizations from the fast-spreading omicron variant of the COVID-19 virus.

In Dallas, Parkland Memorial Hospital reached a record single-day total of visits to the emergency room.

2. Lakeland (Fla.) Regional Health Medical Center

Emergency Room Visits in 2021:  190,581*

Lakeland Regional Health Medical Center in Florida had the second-highest number of emergency room visits in 2021. Lakeland Regional Health ranks as the second busiest emergency department in the nation. The hospital has the second busiest emergency department in the country, according to a report in 2022.

3. NYC Health + Hospitals/Lincoln (New York City)

Emergency Room Visits in 2021: 164,979

NYC Health + Hospitals/Lincoln had the third-highest number of emergency room visits in 2021. The hospital reported 164,979 emergency room visits in the year. Even as coronavirus cases surged in every borough, city Health Department statistics showed that residents of some neighborhoods in New York have been far more likely than others to seek hospital emergency care reporting flu-like symptoms.

 

US hospitals with the fewest emergency room visits

 

These US hospitals saw the fewest emergency room visits in 2021:

1. Denver Health Medical Center

Emergency Room Visits in 2021: 91,015

Denver Health Medical Center had the lowest number of emergency room visits in 2021, with a total of just 91,015 visits recorded. Denver is a city with a small population, which could indicate why there are a smaller number of emergency room visits.

 

2. New York-Presbyterian Queens (New York City)

Emergency Room Visits in 2021: 93,997

New York’s Presbyterian Queens hospital had the second-lowest number of emergency room visits in 2021, with a total of 93,997 visits recorded.

 

3. Luminis Health Anne Arundel Medical Center (Annapolis, Md.)

Emergency Room Visits in 2021: 95,314

Luminis Health Anne Arundel Medical Center in Annapolis, Maryland had the third-lowest number of emergency room visits in 2021. There were a total of 95,314 visits recorded. Luminis Health Anne Arundel Medical Center provides comprehensive emergency services for more than 100,000 area residents each year.

Top Tips for Injuries and Illnesses

With ER departments in high demand, at NiceRx, we wanted to share our expert tips on the injuries and illnesses which require emergency treatment and those that are less of a priority.

Sports Injuries

Sports injuries can be caused by a fall, a heavy blow or not warming up properly before exercising. They could also be caused by pushing yourself too hard or using equipment with poor technique.

Common minor injuries can be treated yourself by

  • Resting the affected part of the body for the first 48 to 72 hours to prevent further damage
  • Regularly applying an ice pack to the affected area during the first 48 to 72 hours, to reduce swelling
  • Using painkillers, such as paracetamol or ibuprofen, to relieve pain
  • If your symptoms are severe or do not improve within a few days or weeks, a doctor may be able to refer you for specialist treatment and support, such as physiotherapy.

Common Illnesses

Most people recover from minor illnesses by themselves and don’t need to be seen by a doctor. For instance, many minor illnesses, including colds and flu, are caused by a virus.

There are often things you can do to ease the symptoms whilst your body gets on with overcoming the virus. Rest and drink plenty of fluid along with paracetamol or ibuprofen to help with fever and aches. Pharmacists can also give you advice on treating minor illnesses.

Methodology

We started with HCUP’s state trends in emergency department visits by payer to find each US state’s number of emergency room visits. Any states without data available were removed. Some states had less recent data including Hawaii which only had data from 2016.

We used HCUP’s visualization of inpatient trends in covid-19 and other conditions to find each state’s number of discharges related to COVID-19 and other illnesses. Some states were removed which did not have relevant data. Some of the data was not collected in 2021, which shows in the data table.

We used Becker’s Hospital Review’s 30 hospitals with the most ER visits to find out which US hospitals had the most ER visits in 2021. The hospital reporting figures that were based on a fiscal year were marked with an asterisk.

Restasis alternatives: which other medications can I take?

Restasis is an FDA-approved (U.S. Food and Drug Administration) brand-name medication manufactured by Allergan, Inc. Restasis eye drops are used to treat chronic dry eye disease that may be caused by inflammation. It is a topical immunomodulator indicated to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca. Increased tear production is not seen in patients taking topical anti-inflammatory drugs or using punctual plugs.

The active ingredient of Restasis is cyclosporine. This substance belongs to a class of drugs that suppress the immune system, leading to an increase in natural tears.

We will look at what Restasis is, what it’s used for, its side effects, interactions, the precautions you should take when using it, and the alternative treatments available.

Restasis dosage

Restasis is available as an ophthalmic emulsion formulation containing cyclosporine 0.5mg/mL. It comes in two forms: single-use vials and Restasis multidose.

Instill one drop of Restasis twice a day in each eye, every 12 hours. Throw the single-use vial away after you use it as the vials don’t contain any preservatives.

Wait at least 15 minutes before using any artificial tears or any other eye drops. Do not touch the dropper on any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an eye infection. Also, to avoid potential eye injury and contamination, be careful not to touch the vial tip to your eye.

Do not use this medicine while wearing contact lenses. Contact lenses may be reinserted 15 minutes after administering Restasis eye drops. Store at room temperature, away from moisture and heat. Do not freeze, and keep the bottle tightly closed when not in use.

You are advised to read the medication guide provided with this medicine for drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Restasis?

The most common side effects of Restasis in clinical trials include the following:

  • Instillation site pain
  • Conjunctival hyperemia (inflammation of the conjunctiva)
  • Mild eye pain, redness
  • Ocular burning sensation
  • Eye irritation, eyelid inflammation (blepharitis)
  • Headache
  • Urinary tract infection
  • Blurred vision

If you experience any of these serious side effects, stop taking Restasis and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Restasis drug interactions

There is currently no data available for Restasis interactions with other medications. Tell your healthcare provider about all the medicines you take, including other eye medications, prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.

Restasis warnings & precautions

You should not use Cequa if you:

  • Are allergic to the active ingredient cyclosporine
  • Have had an allergic reaction to any of the other ingredients in Cequa
  • Are younger than 16 years old

Talk to your doctor before using Cequa if you:

  • Are taking any of the medications that could interact with Cequa
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Restasis, to make sure it is safe for you.

Alternatives to Restasis for dry eyes

Alternatives to Restasis for dry eyes include brand-name medications such as Cequa, Xiidra, and Systane and non-branded medications (generics) such as cyclosporine.

Restasis vs cyclosporine

Restasis eye drops are available in the U.S. as generic cyclosporine ophthalmic eye drops. The generic version was approved in February 2022 and is available as a 0.05% strength (the same as Restasis) in quantities of 30 or 60 single-dose vials. The generic version may be used for the same conditions as Restasis and is just as effective and safe.

Cequa vs Restasis

Cequa is a brand-name eye drop also used for the treatment of dry eye syndrome, a disease of the tears and ocular surface. Neither Cequa nor Restasis are steroid eye drops.

Cequa ophthalmic solution is manufactured by Sun Pharmaceutical Industries, Inc. It is classed as a calcineurin inhibitor immunosuppressant used to increase tear production in patients with keratoconjunctivitis sicca. The active ingredient of Cequa is also cyclosporine which suppresses the activation and function of T-lymphocytes, preventing cell death.

Cequa is available as a cyclosporine ophthalmic solution in preservative-free single-use vials, in doses of 0.9 mg/mL, and is used in the same way you would use Restasis. The side effects and contraindications for Cequa are similar to those for Restasis.

In terms of a cost comparison, Cequa ophthalmic solution 0.09% will cost around $560 for 60, and Restasis ophthalmic emulsion 0.05% will cost around $330 for 30 emulsions.

RELATED: Cequa vs Restasis

Xiidra vs Restasis

Xiidra is also a prescription drug used for the treatment of dry eye syndrome. Xiidra is an FDA-approved prescription eye drop manufactured by Novartis Pharmaceuticals Corporation. Xiidra contains lifitegrast a lymphocyte function-associated antigen-1 (LFA-1) antagonist used to treat the signs and symptoms of dry eye disease (DED) or blepharitis. Xiidra reduces the symptoms of eye dryness and may provide lasting symptom relief.

Xiidra is available as a 5% (50 mg/mL) ophthalmic solution and is used twice daily in the same way you would use Restasis. Side effects of Xiidra are similar to those of Restasis but with the added side effect of dysgeusia (an unusual taste in the mouth). As a guide, Xiidra ophthalmic solution 5% will cost around $590 for 60 mL.

RELATED: Xiidra vs Restasis

Are Restasis and Xiidra the same?

Restasis and Xiidra are not the same. Restasis contains cyclosporine, an immunosuppressive agent, and Xiidra contains lifitegrast, a lymphocyte function-associated antigen-1 antagonist. They have different mechanisms of action for the treatment of dry eye disease.

Is there an over-the-counter alternative to Restasis?

There are a number of over-the-counter alternatives to Restasis available for the treatment of dry eye disease. These include Systane, Artificial Tears, Refresh Tears, Tears Naturale, and HypoTears.

Is there a generic version of Restasis?

Restasis is the trademark brand name for cyclosporine manufactured by Allergan Inc. A generic version of cyclosporine is available. Generic drugs are generally cheaper than brand-name drugs.

What medication do you use to treat dry eye?

The medication you use to treat dry eye disease will depend on the cause. Artificial tears, available without a prescription, are the most common types of treatment for mild dry eye. More severe dry eye conditions may be treated with prescription medications such as Restasis or Cequa (cyclosporine), or Xiidra (lifitegrast). These treatments help to improve tear production by the eye itself.

Non-medication treatments may also be suggested, such as avoiding smoke, or air-conditioned rooms, using humidifiers to keep the air moist, limiting time spent in front of computer screens, using sunglasses, and ensuring you keep hydrated and getting enough sleep can all help with limiting dry eye problems.

Other alternatives, more radical treatment options may include tear duct plugs to stop tears from draining from your eyes or even surgery to help keep tears in your eyes. Speak to your doctor or ophthalmologist for advice as to the best treatment for you.

Creon side effects and how to avoid them

Creon is an FDA-approved brand-name medication manufactured by Abbott Laboratories. It is classified as a pancreatic enzyme replacement therapy (PERT) and is used to help improve digestion by breaking down fats, starches, and proteins in your food. While Creon is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Creon include gastrointestinal side effects. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Creon and what you can do to avoid them.

What is Creon?

Creon is a combination of porcine-derived lipases, proteases, and amylases as active ingredients. It can treat conditions such as cystic fibrosis, chronic pancreatitis, pancreatectomy, and pancreatic cancer, where your pancreas does not produce or release enough enzymes.

Creon releases high levels of lipase, amylase, and protease into the duodenum following activation by its alkaline pH. This facilitates the breakdown of fats into glycerol and free fatty acids, starches into dextrins and sugars, and proteins into amino acids and peptides. The effectiveness of Creon depends on several factors, such as the dose, your gastrointestinal pH, and the microsphere size of the medication.

RELATED: What is Creon

What does Creon do for the pancreas?

Creon replaces the 3 main pancreatic enzymes your pancreas would normally produce every time you eat.

How do you know if you need to take Creon?

If your pancreas doesn’t produce enough digestive enzymes, your body will be unable to break down the foods you eat, and you will not be able to absorb essential nutrients. This may cause malnutrition and symptoms such as diarrhea, gas, bloating, and cramping. Your doctor may carry out tests to check if you have sufficient enzymes produced by your pancreas if you have these symptoms.

What are the side effects of Creon?

The most common possible side effects of Creon include:

  • Abdominal pain
  • Headache
  • Hyperglycemia
  • Hypoglycemia
  • Bloating
  • Flatulence
  • Vomiting
  • Frequent bowel movements
  • Constipation
  • Dizziness
  • Cough
  • Sore throat
  • Weight loss

Some serious side effects of Creon include:

  • Fibrosing colonopathy (scarring of your colon)
  • Worsening of a long-term pancreas problem
  • Increase in uric acid levels
  • Viral infection
  • Allergic reactions (hives, face swelling, throat tightness, trouble breathing)

If you experience any of these serious side effects, stop taking Creon and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Do Creon’s side effects go away?

Some of the less serious side effects of Creon may pass as your body adjusts to this medication. Speak to your doctor if you have more serious long-term side effects that will not go away.

Does Creon cause weight loss?

Yes. Weight loss is a side effect of using Creon

Does Creon cause gas?

Common side effects of Creon include constipation, diarrhea, headache, stomach pain, bloating, gas, nausea, and vomiting.

Does Creon cause diarrhea?

Common side effects of Creon include constipation, diarrhea, headache, stomach pain, bloating, gas, nausea, and vomiting.

Does Creon cause fatigue?

Yes. Creon may cause fatigue. Speak to your doctor if this side effect continues long-term or worsens.

Creon dosage

Creon is available as a delayed-release capsule formulation in the following doses:

  • 6,000 USP lipase units; 19,000 USP units of protease; 30,000 USP units of amylase
  • 12,000 USP lipase units; 38,000 USP units of protease; 60,000 USP units of amylase
  • 24,000 USP lipase units; 76,000 USP units of protease; 120,000 USP units of amylase

Your dose will be based on your body weight or the amount of fatty food you eat. Do not switch Creon with other pancreatic enzyme products (such as Pancrease or Zenpep) without talking to your doctor. Take Creon capsules with a meal or snack, but make sure you don’t exceed your total daily dose.

If you cannot swallow capsules, open the capsule and sprinkle the contents on applesauce before consuming. Drink water or juice to be sure there is no Creon left in your mouth. If you forget to take Creon, skip the missed dose and take your next dose as scheduled. Do not double up your doses.

You are advised to read the medication guide provided with this medicine for drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: Creon Dosage

What happens if you take too much Creon?

Any excess Creon your body does not need passes through your bowel and is excreted.

Creon drug interactions

While no drug interactions of Creon have been identified, you should make sure your doctor is aware of all the medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Creon’s warnings & precautions

You should not use Creon if you:

  • Are allergic to pork or any pig products
  • Have known hypersensitivity to Creon or any of its inactive ingredients

Talk to your doctor before using Creon if you:

  • Have or have ever had fibrosing colonopathy
  • Have or have ever had any intestinal blockages
  • Have kidney disease
  • Have gout
  • Have high blood uric acid (hyperuricemia)
  • Have trouble swallowing capsules
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed – It is not known if Creon is excreted in breast milk

You should always check with your doctor or pharmacist before taking any medication, including Creon, to make sure it is safe for you.

Is Creon safe for pregnant women?

It is not known if pancrelipase causes fetal harm and should only be given to a pregnant woman if the benefits outweigh the risks.

What foods should be avoided when taking Creon?

You may need to make changes to your diet when taking Creon. Foods high in fat, protein, and carbohydrates may be difficult to digest and can make your symptoms worse. You should avoid:

  • Foods rich in fiber such as lentils, barley, and brown rice
  • Fried food
  • Processed meats
  • Alcohol
  • Large meals – avoid large meals, instead eat 3 to 5 small meals each day

Speak to your doctor or dietitian about which foods you should or shouldn’t eat while using Creon. They will be able to help you create a healthy balanced diet plan that meets your dietary needs.

How to avoid Creon side effects

The best way to avoid side effects is to take Creon as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Creon that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Creon. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can worsen side effects.

4. Avoid alcohol

Avoid drinking alcohol while taking Creon, as it can increase your risk of stress and make your condition worse. Speak to your healthcare provider about alcohol consumption while receiving treatment with Creon.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Creon.

7. Know the signs and symptoms of Creon’s side effects

Signs and symptoms of side effects include diarrhea, gas, and stomach pain. If you experience any of these symptoms long-term or if these side effects become worse, speak to your doctor for medical advice.

8. Monitor your weight

Creon may cause weight loss. If you experience this side effect while taking Creon, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Creon.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Creon as needed.

Cimzia side effects and how to avoid them

Cimzia is an FDA-approved brand-name medication manufactured by UCB, Inc. It is a biologic drug classed as a tumor necrosis factor blocker or anti-TNFs and is used to treat autoimmune diseases. While Cimzia is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Cimzia include upper respiratory tract infections. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Cimzia and what you can do to avoid them.

What is Cimzia (certolizumab pegol)?

Cimzia is used to treat a range of inflammatory autoimmune diseases in adults, including:

Cimzia works as a monoclonal antibody and, more specifically, as a TNF blocker, to treat inflammation. TNF alpha (tumor necrosis factor-alpha) is one of several antibodies produced by white blood cells and other parts of the immune system.

Once Cimzia is injected into your body, its active ingredient helps reduce inflammation. Your immune system releases a protein in your body to trigger inflammation called TNF-alpha (tumor necrosis factor-alpha). The active ingredient in Cimzia attaches to TNF-alpha and stops it from working. This limits the amount of inflammation your immune system can cause.

By reducing inflammation, Cimzia can provide relief from the symptoms of inflammatory diseases. It can also limit the damage caused by inflammatory diseases and can stop flare-ups from happening.

What are the most common side effects of Cimzia?

The most common possible side effects of Cimzia include:

  • Injection site reactions
  • Urinary tract infections
  • Upper respiratory infections
  • Abdominal pain
  • Sinus infection
  • Headache
  • Joint pain

Serious side effects include:

  • Suppression of the immune system
  • Increased risk of cancer, particularly lymphoma and skin cancer
  • New or worsening heart failure
  • New or worsening psoriasis
  • Eye disorders such as optic neuritis, uveitis, and retinal hemorrhage
  • Serious allergic reactions – hives, trouble breathing, swelling of your face, lips, tongue, or throat
  • Serious infections – fever, sore throat, cough, night sweats, shortness of breath, painful urination, unusual vaginal discharge, oral thrush
  • Lupus-like syndrome (pain and inflammation in the body)
  • Reactivation of a hepatitis B virus

If you experience any of these serious side effects, stop taking Cimzia and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

How long do Cimzia side effects last?

Cimzia’s side effects may last a few days to weeks. If side effects last longer or become more severe, speak with your doctor for medical advice.

Does Cimzia cause hair loss?

Hair loss is seen in some patients who have an immune system flare-up while being treated with Cimzia. Hair loss is a complete loss of hair on the head, known as alopecia totalis.

Does Cimzia affect your eyes?

Cimzia may cause eye problems such as optic neuritis, uveitis, and retinal hemorrhage.

Does Cimzia cause fatigue?

Cimzia may cause tiredness. For those taking Cimzia for rheumatoid arthritis, tiredness affected around 3% of people taking Cimzia with methotrexate.

Does Cimzia make cause weight gain?

No, Cimzia does not cause weight gain or weight loss. Speak to a healthcare professional if you experience any changes in weight while taking Cimzia.

What does Cimzia do to the body?

Cimzia helps to reduce symptoms such as joint swelling, pain, morning stiffness, and tiredness.

Cimzia dosage

Cimzia is available for injection as 200 mg lyophilized powder in a single-dose vial and 200 mg/mL solution in a single-dose prefilled syringe.

You take Cimzia by injecting it under your skin subcutaneously, either in a pre-filled syringe yourself or by injections administered by your healthcare provider. The dose of Cimzia and how many injections you need will be decided upon by your prescribing doctor based on your condition and medical history.

You are advised to read the medication guide provided with this medicine for drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cimzia drug interactions

Cimzia can interact with other medications, including:

  • Live vaccines
  • Anakinra
  • Abatacept
  • Rituximab
  • Cyclophosphamide

Other medical conditions may affect your treatment with Cimzia, so you should always seek medical advice from the healthcare professional prescribing your drugs. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

Cimzia warnings & precautions

Don’t take Cimzia if:

  • Are allergic to the active ingredient certolizumab pegol
  • Are allergic to any of the other ingredients in Cimzia
  • Are under 18 years of age

Talk to your doctor before taking Cimzia if you:

  • Have or have ever had congestive heart failure
  • Have or have ever had any kind of blood disorder
  • Have or have ever had any condition that affects your nervous system, like multiple sclerosis or Guillain-Barré syndrome
  • Often get infections, or have infections that keep coming back
  • Have or have ever had hepatitis B
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Cimzia, to ensure it is safe.

Is Cimzia a high-risk medication?

Cimzia may increase the risk for certain types of cancers. Children and young adults may also be at a higher risk of developing lymphoma (lymph node cancer).

Cimzia also has an increased risk of causing serious infections such as tuberculosis, invasive fungal infections, and bacterial sepsis, which may lead to hospitalization or death.

What are the risks of Cimzia?

Cimzia may cause problems with the nervous system, such as optic neuritis, multiple sclerosis, and peripheral neuropathy. Or it may make these conditions worse.

How to avoid Cimzia side effects

The best way to avoid side effects is to take Cimzia as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Cimzia that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Cimzia. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is safe to consume when you are taking Cimzia. However, Cimzia is often taken with methotrexate which, if taken with alcohol, may cause further liver damage.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Cimzia.

7. Know the signs and symptoms of Cimzia side effects

Signs and symptoms of side effects include urinary and respiratory infections. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Cimzia.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Cimzia as needed.

Invokana alternatives: which other medications can I take?

Invokana is an FDA-approved (U.S. Food and Drug Administration) medication manufactured by Janssen Pharmaceuticals, Inc. It’s usually prescribed with exercise and changes to diet to help manage blood sugar levels. Invokana helps with type 2 diabetes by increasing the amount of sugar that’s removed from your body in your urine. This helps to keep your blood sugar levels lower. Invokana is taken orally as a tablet swallowed with water.

With type 2 diabetes, a lack of insulin, or insulin that no longer works effectively, causes you to have too much sugar in your blood. Having high blood sugar can make you feel hungry, thirsty, and tired. But, over time, high blood sugar can have more serious consequences. It can cause a range of health problems, including heart attacks, heart disease, strokes, and kidney disease.

Learn more about Invokana alternatives, including cheaper alternatives that could help you save money.

What is Invokana?

The active ingredient in Invokana is called canagliflozin. It helps to lower your blood sugar by blocking a process in your body that reabsorbs sugar (glucose) from your urine. This increases the amount of sugar in your urine and causes you to lose more sugar than you would normally do when you urinate. Used alongside exercise and improvements in your diet, and sometimes other diabetes medications, canagliflozin can help you maintain a lower blood sugar level.

Is Invokana a generic drug?

Invokana is not a generic drug, it is the brand name for a medicine manufactured by Janssen Pharmaceuticals, Inc. The active ingredient in Invokana is called canagliflozin, which is prescribed with exercise and changes to diet to help manage your blood sugar levels.

Are Jardiance and Invokana the same?

Both Jardiance and Invokana are FDA-approved diabetes drugs belonging to the drug class known as sodium-glucose co-transporter 2 inhibitors (SGLT 2 inhibitors). They are both diabetes medicines prescribed with changes in diet and exercise to help manage blood glucose levels.

The active ingredient in Invokana is called canagliflozin, and the active ingredient in Jardiance is called empagliflozin. As Jardiance and Invokana belong to the same class of drugs, they both work in the same way. Both drugs are used to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and cardiovascular disease and to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure.

Jardiance also has similar side effects, drug interactions, and contraindications to Invokana. The extent to which each of these drugs affects an individual will depend on a number of factors, including the condition being treated, the age, sex, and other medications being taken.

Farxiga vs Invokana

Both Farxiga and Invokana are FDA-approved diabetes drugs belonging to the drug class known as sodium-glucose co-transporter 2 inhibitors (SGLT 2 inhibitors). They are both diabetes medicines prescribed with changes in diet and exercise to help manage blood glucose levels. The active ingredient in Farxiga is called dapagliflozin which works in the same way as canagliflozin in Invokana and empagliflozin in Jardiance.

Farxiga, like Jardiance, also has similar side effects, drug interactions, and contraindications to Invokana, and as with Jardiance and Invokana, the extent to which its side effects affect an individual will depend on the condition being treated, the age, sex, and other medications being taken.

Are Januvia and Invokana the same?

Januvia contains sitagliptin as the active ingredient. It is a dipeptidyl peptidase 4 inhibitor (DPP-4 inhibitor) also used to treat type 2 diabetes, by helping to lower blood sugar levels when used in combination with exercise and changes to your diet. However, because Januvia belongs to a different class of medication, it has a different mechanism of action than Invokana and is not the same.

Januvia treats type 2 diabetes by helping to lower your blood sugar levels. When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP. These hormones make your pancreas secrete insulin. As you continue to digest your food, the digestive hormones are broken down by an enzyme called DPP-4 to allow your levels of insulin to fall again.

Sitagliptin stops the DPP-4 enzyme from breaking down the digestive hormones. This keeps the hormones active for longer, making you produce more insulin, and lowering your blood sugar to normal levels.

Is weight loss a side effect of Invokana?

Invokana is not FDA-approved for weight loss, but it may help you lose weight as a side effect. On average Invokana helps patients lose 2 to 3 % in body weight. How much weight you lose may be influenced by your condition and other medication you may be using. You should speak to your doctor for medical advice if you are thinking about weight loss while using Invokana.

Can people who are diabetic take Invokana?

Invokana is an FDA-approved (U.S. Food and Drug Administration) medication prescribed with exercise and changes to diet to help manage blood sugar levels in patients with type 2 diabetes. Speak to your healthcare provider for more information about Invokana and being treated for diabetes.

Common side effects of Invokana

The most common side effects of Invokana in clinical trials include nausea, constipation, genital yeast infections, urinary tract infections, and hypoglycemia (low blood sugar). More serious side effects of Invokana include allergic reactions, kidney failure, serious urinary tract infections, Increased risk of bone fracture, and diabetic ketoacidosis, a potentially life-threatening condition where your body breaks down too much fat too quickly, causing you to produce high levels of blood acids called ketones.

Invokana drug interactions

Invokana can interact with a range of other medications. These include other antidiabetic drugs such as insulin or sulfonylureas, medications used to lower your blood pressure, anticonvulsants, treatments for HIV, rifampicin for the treatment of tuberculosis, cholestyramine used to reduce cholesterol levels, digoxin used to treat certain heart problems, blood thinners, and St John’s wort.

Invokana contraindications

You should not use Invokana if you are allergic to the active ingredient canagliflozin or to any of the other ingredients in Invokana, have type 1 diabetes, or are breastfeeding or are planning to breastfeed.

You should talk to your doctor before using Invokana if you have diabetic ketoacidosis (a diabetes complication that can cause rapid weight loss), have had a serious heart condition or a stroke, have severe liver or kidney problems, have had a lower limb amputation, are under 18 years of age, are pregnant or are trying to get pregnant, or are intolerant of some sugars.

Alternatives to Invokana

Natural alternatives to Invokana

Natural alternatives to Invokana may include non-prescription alternatives such as herbal or homeopathic supplements. It is important to be aware, however, that products sold or supplied as natural remedies for the treatment of diabetes will not have undergone the same rigorous testing prescription drugs have and may not be safe or effective when managing the symptoms of diabetes. Speak to a healthcare professional for medical advice about potential allergic reactions or drug interactions before using natural alternatives.

Changes in lifestyle, such as a low-carb diet, exercise, and weight loss, are the best natural way to help manage your diabetes. Speak to your doctor or dietitian for advice on creating your own personal diet plan.

Does Invokana have a generic alternative?

Effective generic alternatives to Invokana for the treatment of Type 2 diabetes include such drugs as metformin, glipizide, and glyburide. Generic alternatives are normally more cost-effective than branded versions of drugs.

 

Amitiza side effects and how to avoid them

Amitiza is an FDA-approved brand-name medication manufactured by Takeda Pharmaceuticals. It is classified as a laxative and is used for the treatment of chronic idiopathic constipation (CIC) in adults. It is also used to treat constipation from various other causes in adults. While Amitiza is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Amitiza include diarrhea and abdominal pain. Less common, but more serious side effects, can include low blood pressure.

Learn more about the side effects of Amitiza and what you can do to avoid them.

What is Amitiza (lubiprostone)?

Amitiza (lubiprostone) is a chloride channel activator that is used to increase fluid secretion in your intestines to soften your stool, increase gastrointestinal motility, and encourage spontaneous bowel movements (SBM). Amitiza is approved by the U.S. Food and Drug Administration (FDA) to treat the following conditions in adults:

  • Chronic idiopathic constipation (CIC)
  • Opioid-induced constipation (OIC) in patients taking opioid drugs for chronic non-cancer pain. The effectiveness of Amitiza in the treatment of OIC in patients taking Dolophine (methadone) has not been established
  • Irritable bowel syndrome with constipation (IBS-C) in women ≥18 years old

The safety and efficacy of Amitiza have not been established in pediatric patients under the age of 18.

Lubiprostone is a fatty acid derived from prostaglandin E1 that activates the CIC-2 chloride channels in your gastrointestinal epithelial cells. By activating the CIC-2 channels, lubiprostone increases the secretion of chloride-rich fluid in your intestines without affecting your serum electrolyte concentrations. Increasing fluid secretion helps improve GI motility and promote spontaneous bowel movements (SBM). In clinical studies, this reduced symptoms such as bloating, abdominal discomfort, and straining within 1 week.

Is Amitiza for chronic constipation?

Amitiza is for the treatment of chronic idiopathic constipation and constipation-predominant irritable bowel syndrome and postoperative ileus.

What are the benefits of Amitiza?

Amitiza helps to improve symptoms such as abdominal discomfort, bloating, stool texture, reducing strain, and the feeling of not completely relieving yourself.

How long does it take for Amitiza to work?

Around 60% of patients have a bowel movement within 24 hours of taking Amitiza and 80% have a bowel movement within 48 hours. This was at a significantly higher rate when compared to the placebo.

What are the most common side effects of Amitiza?

The most common possible side effects of Amitiza include the following:

  • Nausea
  • Diarrhea
  • Headache
  • Abdominal pain
  • Abdominal distension
  • Flatulence
  • Vomiting
  • Loose stools
  • Lightheadedness and dizziness
  • Fatigue
  • Dry mouth

Amitiza can cause serious adverse events, including:

  • Hypersensitivity reactions including hives, angioedema, and trouble breathing
  • Severe diarrhea
  • Low blood pressure and fainting
  • Shortness of breath
  • Chest tightness or pain

This is not a complete list of the possible side effects of Amitiza. Contact your healthcare provider for medical advice about any serious side effects you experience while taking Amitiza. You can report your side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Does Amitiza cause weight loss?

Weight loss or weight gain are not side effects of taking Amitiza. If you experience changes in weight while taking this medication, speak to your doctor for medical advice.

Does Amitiza cause hair loss?

Hair loss has been reported in females over the age of 60 who have been taking Amitiza for less than 1 month.

Does Amitiza make you tired?

Tiredness is a common side effect of Amitiza. Speak to your doctor if this side effect worsens.

Amitiza dosage

Amitiza is available as an oval, soft gelatin capsule containing 8 mcg or 24 mcg of lubiprostone with “SPI” printed on one side.

Take Amitiza exactly as your healthcare professional prescribes it to you. Do not change your dose or stop taking Amitiza without discussing it with them. Amitiza is typically taken twice daily. Taking Amitiza with food and water can help reduce the risk of nausea. You should swallow the Amitiza capsules whole. Do not break, crush, or chew Amitiza capsules. Store Amitiza at room temperature between 15°C-30°C (59°F-86°F) away from light and extreme temperatures.

You are advised to read the medication guide provided with this medicine for drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What is the maximum amount of Amitiza to be taken in a day?

The maximum dose is 48 mcg per day.

What should you do if you miss a dose of Amitiza?

If you forget to take a dose of Amitiza, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose and your normal scheduled time. Do not take extra doses to make up for a missed dose.

What time of day should Amitiza be taken?

Amitiza is taken either once in the morning and once in the evening or once daily. Your healthcare provider will tell you how to take it.

Amitiza drug interactions

When Amitiza is taken with other drugs, it may change the way they work or increase the frequency and severity of side effects. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take.

Amitiza warnings & precautions

Don’t take Amitiza if you:

  • Have had an allergic reaction to Amitiza or any of its inactive ingredients in the past
  • Have known bowel obstruction

Talk to your doctor before taking Amitiza if you:

  • Have liver disease
  • Have an abdominal obstruction or blockage
  • Have severe diarrhea
  • Are pregnant, plan on becoming pregnant
  • Are breastfeeding or plan to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Amitiza, to make sure it is safe for you.

Can I drink alcohol while taking Amitiza?

Alcohol consumption is safe in moderation and is not known to interact with Amitiza. Alcohol may, however, increase side effects such as nausea and dizziness.

How to avoid Amitiza side effects

The best way to avoid side effects is to take Amitiza as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Amitiza that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Amitiza. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Amitiza.

6. Know the signs and symptoms of Amitiza side effects

Signs and symptoms of side effects include diarrhea and flatulence. If you experience any of these symptoms, speak to your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Amitiza.

8. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Amitiza as needed.

Advair side effects and how to avoid them

Advair is an FDA-approved brand-name medication manufactured by GSK (GlaxoSmithKline). It contains an anti-inflammatory medicine (fluticasone propionate) and a long-acting bronchodilator (salmeterol). It is used to prevent asthma attacks and flare-ups or worsening of chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis or emphysema. While Advair is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Advair include sore throats and oral thrush. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Advair and what you can do to avoid them.

What is Advair (fluticasone/salmeterol)?

Advair is a prescription medication used to prevent the symptoms of asthma in adults and children 12 years of age and older. Advair contains the fluticasone propionate/salmeterol combination. When inhaled, these ingredients work together to open up your lungs and airways. Fluticasone propionate is a type of corticosteroid. When you inhale Advair, molecules of fluticasone propionate attach to areas on the surface of the cells in your airways and lungs called glucocorticoid receptors. This stimulates the receptors, making them produce lower amounts of the substances that trigger inflammation and greater amounts of anti-inflammatory proteins. This helps to reduce inflammation throughout your lungs and airways.

Salmeterol is a medication called a long-acting beta 2-adrenergic agonist (LABA). It attaches to areas on the outside of muscle tissue in your airways and lungs called beta-2 receptors. This stimulates the receptors, causing them to relax the muscle tissue, opening up your lungs and airways.

What are the most common side effects of Advair?

The most common side effects of Advair in clinical trials include the following:

  • Headaches
  • Dizziness
  • Nausea, vomiting
  • Sore throat
  • Throat irritation
  • Hoarseness and changes to your voice
  • An increase in upper respiratory chest infections

More serious side effects of Advair include

  • A weakened immune system, making you more vulnerable to infections, including serious infections like tuberculosis
  • Adrenal insufficiency
  • Life-threatening allergic reactions to the medication cause hives, and swelling in your face, mouth, and throat, which can make it difficult to breathe
  • A sudden worsening of your asthma symptoms, including asthma attacks (paradoxical bronchospasm)
  • Fungal infections (candida/thrush) in your mouth and throat – this is less likely if you rinse your mouth out with water after taking your Advair Diskus
  • Increased blood pressure
  • A fast and/or irregular heartbeat
  • A thinning and weakening of bones (osteoporosis)
  • An increased risk of eye problems, including glaucoma, cataracts, and blurred vision
  • An increased risk of developing pneumonia if you also have chronic obstructive pulmonary disease (COPD)
  • Slowed rates of growth in children

These aren’t all the possible side effects Advair can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to your physician or pharmacist. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the immediate side effects of Advair?

The more immediate side effects of Advair include dizziness, headaches, throat irritation, nausea, vomiting, coughing, oral thrush, muscle pain, or upper respiratory infections.

Does Advair have long-term effects?

Advair contains an inhaled corticosteroid, fluticasone, which can cause long-term side effects such as slow growth rate in children, the development of cataracts and glaucoma, weakening of bones, increasing the risk of fractures and osteoporosis, and reducing the function of adrenal glands.

Does Advair affect teeth?

Advair may affect tooth and gum care as it may increase your risk of dental decay and mouth sores, especially in children.

Does Advair cause anxiety?

Anxiety has been reported in rare cases with Advair HFA since the drug became available for use.

Does Advair cause weight gain?

Advair may cause weight gain in 1% to 3% of people who use Advair HFA. Speak to your doctor if you are concerned about weight gain as a side effect of Advair.

Does Advair affect heart rate?

Salmeterol may increase heart rate in some patients. Speak to your doctor if you experience this side effect.

What does Advair do to your lungs?

Advair helps to relieve symptoms such as coughing, wheezing, difficulty breathing, and shortness of breath by relaxing the airways in your lungs.

Advair dosage

Advair Diskus is available in an oral inhalation powder in the following doses: Fluticasone propionate (100, 250, or 500 mcg) and salmeterol (50 mcg) as an oral inhalation powder.

Advair HFA inhalation aerosol is available as 45 mcg fluticasone propionate/21 mcg salmeterol per actuation, 115 mcg fluticasone propionate/21 mcg salmeterol per actuation, and 230 mcg fluticasone propionate/21 mcg salmeterol per actuation.

Advair Diskus and Advair HFA are both used twice a day. The recommended starting dose is based on the severity of your asthma. Please read the prescribing information and drug information and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

How long does it take for Advair to take effect?

Advair may take up to a week before you see its full effects. Speak to your doctor if your condition becomes worse or does not improve.

Advair drug interactions

Advair can interact with other medications, including:

  • Any other medications taken to treat asthma or other breathing problems
  • Any other medications that contain steroids
  • Any other medications that contain a long-acting beta agonist (LABA)
  • Any medications taken for the treatment of water retention such as diuretics
  • MAOi inhibitors
  • Antidepressants
  • Any medications taken to treat bacterial, viral, or fungal infections, including an HIV infection, such as ketoconazole, itraconazole, ritonavir, nelfinavir, or cobicistat

Advair can interact with other medications. This can change how Advair Diskus and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Advair warnings & precautions

You should not use Advair if you:

  • Are allergic to the active ingredients fluticasone, salmeterol, or milk proteins
  • Have had a serious allergic reaction to any of the other ingredients in Advair
  • Have sudden breathing problems, like an asthma attack. Use a rescue inhaler to treat sudden breathing problems
  • Are under 12 years of age

Talk to your doctor before using Advair if you:

  • Are taking any of the medications that could interact with Advair
  • Have any problems with your immune system
  • Have any liver problems
  • Have any heart problems
  • Have diabetes
  • Have osteoporosis
  • Have high blood pressure
  • Have any thyroid problems
  • Have any eye problems, including cataracts or glaucoma
  • Have or have ever had any problems with your adrenal glands
  • Have an active infection
  • Have recently been around someone who has measles or chickenpox
  • Have or have ever had a seizure
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Advair, to make sure it is safe for you.

Is it possible to overdose on Advair?

Yes. Overdosing may lead to symptoms such as chest pain, fast or irregular heartbeat, shakiness, feeling weak, nausea, vomiting, headaches, and seizures.

Is it safe to drink alcohol when using Advair?

Alcohol is safe to consume in moderation when using Advair. Avoid smoking, however, as this will make your symptoms worse and your treatment less effective.

How to avoid Advair side effects

The best way to avoid side effects is to take Advair as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Advair that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Advair. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Advair.

6. Know the signs and symptoms of Advair side effects

Signs and symptoms of side effects include sore throats and oral thrush. If you experience any of these symptoms, speak to your doctor for medical advice.

7. Monitor your weight

Advair may cause weight gain. If you experience this side effect while taking Advair, get medical advice from your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Advair.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Advair as needed.

Viberzi side effects and how to avoid them

Viberzi is an FDA (Food and Drug Administration) approved medication manufactured by Allergan USA. It is classified as a mu-opioid receptor agonist and is used to treat irritable bowel syndrome where the main symptom is diarrhea (IBS-D). While Viberzi is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Viberzi include constipation and stomach pain. Less common but more serious side effects can include pancreatitis.

Learn more about the side effects of Viberzi and what you can do to avoid them.

What is Viberzi (eluxadoline)?

Viberzi is a mu and kappa opioid receptor agonist and a delta opioid receptor antagonist. When Viberzi acts on opioid receptors in the stomach and intestines, secretions from the stomach and pancreas are reduced. This slows down the movement of food and delays digestion. Activity at multiple opioid receptors treats the symptoms of IBS-D while reducing the likelihood of constipation.

How long does Viberzi stay in your system?

Viberzi has a half-life of around 4 to 6 hours, so it will stay in your bloodstream for 30 hours after your last dose.

Is Viberzi a narcotic?

No, Viberzi is not a narcotic. It does work on some of the same receptors as opioid pain medications, but it has a lower risk of abuse and dependence. Viberzi is a Schedule IV controlled substance that does carry the risk of dependence. But according to its manufacturer, Viberzi was designed to have a low risk for abuse and a low potential for dependence.

What should you not do with Viberzi?

Do not take medications that may cause constipation, such as Lotronex (alosetron), loperamide, anticholinergic medicines, or opioid pain medications, as these will increase the risk of side effects such as constipation and abdominal pain.

Can you take Viberzi long-term?

Viberzi may be taken for as long as your doctor recommends it to be taken. Symptoms of IBS-D may return if you discontinue treatment with Viberzi.

How long does Viberzi take to work?

Benefits of using Viberzi will be seen within the first week of treatment, with maximum benefits seen at 6 weeks.

Is Viberzi a stimulant?

Viberzi is not a stimulant. It belongs to a class of drugs known as mu-opioid receptor agonists.

What are the most common side effects of Viberzi?

The most common side effects of Viberzi in clinical trials include:

  • Constipation
  • Stomach pain
  • Nausea
  • Common cold symptoms
  • Bloating
  • Dizziness
  • Vomiting
  • Gas
  • Rash

Viberzi can cause serious side effects, including:

  • Life-threatening allergic reactions, including hives and trouble breathing
  • Pancreatitis
  • Severe constipation
  • Liver impairment

If you experience any of these serious side effects, stop taking Viberzi and seek medical attention immediately. You are recommended to report any side effects of prescription medications to the U.S. Food and Drug Administration (FDA). Go to www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Viberzi cause weight gain?

There is no change in weight that is associated with taking Viberzi. If you experience an unexplained change in your weight, notify your doctor.

Viberzi dosage

Viberzi is available as 75mg and 100 mg tablets. Take Viberzi exactly as your healthcare provider prescribes it to you twice daily with food. If you think you have taken too much Viberzi, call your healthcare provider or go to the nearest hospital emergency room right away. Store Viberzi at room temperature between 59°F to 86°F (15°C to 30°C).

You are advised to read the complete prescribing information, medication guide, and drug information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What should you do if you miss a dose of Viberzi?

If you forget to take a dose of Viberzi, take your next dose at your usual time. Do not take extra doses of Viberzi to make up for missed doses.

Viberzi drug interactions

When Viberzi is taken with other drugs, it may change how they work or increase the frequency and severity of side effects. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take, including:

  • Cyclosporine
  • Gemfibrozil
  • Rifampin
  • Eltrombopag
  • Rosuvastatin

Viberzi warnings & precautions

Don’t take Viberzi if you:

  • Have a known hypersensitivity to eluxadoline or any other ingredients in Viberzi
  • Don’t have a gallbladder or have a current or past blockage in their gallbladder
  • Have sphincter of Oddi disease or dysfunction
  • Have a history of alcohol addiction, alcohol abuse or drink more than 3 alcoholic beverages a day
  • Have inflammation of the pancreas (pancreatitis) or a blockage
  • Have severe liver impairment
  • Have chronic or severe constipation

Talk to your doctor before taking Viberzi if you:

  • Have new or worsening abdominal pain, nausea, or vomiting – Viberzi causes an increased risk of pancreatitis and sphincter of Oddi spasm
  • Have previously had serious allergic reactions, including anaphylaxis when taking Viberzi
  • Have liver problems
  • Are currently pregnant, or  are planning on becoming pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Viberzi, to make sure it is safe for you.

How to avoid Viberzi side effects

The best way to avoid side effects is to take Viberzi as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your healthcare provider. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Viberzi that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Viberzi. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Viberzi as it can increase your risk of pancreatitis (inflammation of the pancreas)

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Viberzi.

7. Know the signs and symptoms of Viberzi side effects

Signs and symptoms of side effects include constipation and stomach pain. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Viberzi should not cause weight gain or weight loss. If you experience any changes in weight while taking Viberzi, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Viberzi.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Viberzi as needed.

Motegrity side effects and how to avoid them

Motegrity is an FDA-approved brand-name medication manufactured by Takeda Pharmaceuticals, originally developed by Shire. It is classified as a serotonin receptor agonist and is used in adults for the treatment of chronic idiopathic constipation (CIC) and for the treatment of irritable bowel syndrome with constipation (IBS-C). While Motegrity is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Motegrity include abdominal pain, bloating, and diarrhea. Less common but more serious side effects can include changes in mood and depression.

Learn more about the side effects of Motegrity and what you can do to avoid them.

What can Motegrity be taken for?

It is a prescription medicine given to adults for the treatment of chronic idiopathic constipation (CIC) and for the treatment of irritable bowel syndrome with constipation (IBS-C). Chronic idiopathic constipation can be treated by making lifestyle changes, like eating more dietary fiber, increasing your water intake, and taking regular physical exercise. But often, this may prove insufficient, particularly with stubborn cases. If you have chronic idiopathic constipation, your doctor may have prescribed Motegrity to you.

The active ingredient in Motegrity is called prucalopride. It’s a type of drug called a serotonin receptor agonist that can speed up how quickly food moves through your digestive system, also known as motility. Muscles in your bowels rhythmically contract (tighten) and relax to move food through your bowels. This process is called peristalsis, and if it happens too slowly, it can cause constipation as the food in your bowels hardens over time. Motegrity can help to stop this from happening. Motegrity stimulates colonic peristalsis and bowel motility by causing acetylcholine release in gastrointestinal neurons.

When you take Motegrity, the active ingredient prucalopride is released into your bowels. It attaches to areas on the outside of the cells in your bowels called 5-HT4 serotonin receptors. This stimulates the receptors, making them produce a natural substance called acetylcholine. The acetylcholine makes your bowel muscle contract faster, speeding up peristalsis and motility.

What are the side effects of Motegrity?

The most common side effects of Motegrity in clinical trials compared to placebo include:

  • Headaches
  • Fatigue
  • Dizziness
  • Gastrointestinal disorders – flatulence (gas), bloating, abdominal pain, diarrhea
  • Nausea (feeling sick)
  • Vomiting (being sick)

More serious side effects of Motegrity include:

  • Severe allergic reactions – swelling of your tongue, mouth, or throat, trouble breathing
  • Mood problems, including depression and suicidal thoughts and actions
  • Ongoing or worsening depression

If you experience any of these serious side effects, stop taking Motegrity and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Motegrity?

Long-term side effects of Motegrity include changes in mood or behavior and suicidal thoughts and behavior. Speak to your doctor if you experience these side effects.

Does Motegrity cause hair loss?

Hair loss is not a side effect reported with Motegrity.

Do side effects of Motegrity go away?

Side effects reported in the first week of treatment, such as diarrhea or headaches, normally pass within a couple of days.

Does Motegrity cause weight gain?

Weight gain is not a side effect reported with Motegrity.

Does Motegrity cause loss of appetite?

Motegrity may cause a loss of appetite as a side effect.

What is the proper dosage of Motegrity?

Motegrity is available in 1mg or 2 mg tablets of prucalopride. Take Motegrity with or without food once daily to increase the speed at which food moves through your bowels, helping you have more frequent and regular bowel movements. The recommended adult dose is 2 mg once daily. Patients with severe renal impairment (creatinine clearance (CrCL) less than 30 mL/min) are recommended to take 1 mg once daily.

If you forget to take a dose of Motegrity, take it as soon as you remember, but skip the missed dose if it is nearly time for your next dose. Store Motegrity in its original container at room temperature, away from heat and moisture.

You are advised to read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Does Motegrity need to be taken with food?

Motegrity may be taken once a day, with or without food.

When is the best time of day to take Motegrity?

Motegrity may be taken at any time of the day. It should be taken once a day with or without food.

How long does Motegrity take to work?

Motegrity will take between 1 to 5 days to start working. This will vary from person to person and is only a guideline for when to expect it to work.

Motegrity drug interactions

Motegrity can interact with other medications, including:

  • Anticholinergics – atropine, cyclizine, procyclidine
  • Antimuscarinics – oxybutynin
  • ACE inhibitors – captopril
  • Antifungals – itraconazole, ketoconazole
  • Calcium channel blockers – nifedipine, verapamil
  • Other medications you’re taking to treat your constipation

Motegrity and can interact with other medications. This can change how Motegrity and other medications work and can make side effects more likely. Tell your prescribing physician about all drugs you’re taking, including vitamins and dietary supplements. In particular, tell them if you’re taking medicines that increase the risk of diarrhea, like laxatives, medicines for stomach ulcers, and NSAIDs.

Motegrity warnings & precautions

You should not use Motegrity if you:

  • Are allergic to the active ingredient prucalopride, or any of the other ingredients in Motegrity
  • Have a blockage in your stomach or bowels (intestinal obstruction)
  • Have an intestinal perforation
  • Have obstructive ileus
  • Have severe inflammatory conditions such as Crohn’s disease, ulcerative colitis, and toxic megacolon/megarectum
  • Are under 18 years of age

Talk to your doctor before using Motegrity if you:

  • Have or have ever had depression
  • Have or have ever had suicidal thoughts or tried to commit suicide
  • Have kidney disease or any other kidney problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – The ingredients in Motegrity may pass through breast milk

How to avoid Motegrity side effects

The best way to avoid side effects is to take Motegrity as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Motegrity that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Motegrity. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol does not affect the use of this medication but may cause the same side effects as Motegrity. Speak to your healthcare provider for further medical advice.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Motegrity.

7. Know the signs and symptoms of Motegrity side effects

Signs and symptoms of side effects include headaches, dizziness, and tiredness. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Motegrity does not cause weight gain or weight loss. If you experience changes in your weight while taking Motegrity, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Motegrity.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Motegrity as needed.

Norditropin side effects and how to avoid them

Norditropin is an FDA-approved medication manufactured by Novo Nordisk A/S. It is classified as a human growth hormone (HGH) and is used for growth failure. While Norditropin is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Norditropin include upper respiratory infections. Less common but more serious side effects can include hyperglycemia and serious allergic reactions.

Learn more about the side effects of Norditropin and what you can do to avoid them.

What is Norditropin (somatropin)?

Norditropin is a recombinant human growth hormone indicated for:

  • Treatment of children with growth failure due to growth hormone deficiency (GHD), short stature associated with Noonan syndrome, (idiopathic short stature) associated with Turner syndrome, and born small for gestational age (SGA) with no catch-up growth by 2 to 4 years of age
  • Treatment of adults with either adult onset or childhood-onset GHD

What are the side effects of Norditropin?

The most common side effects of Norditropin include:

  • Injection site reactions
  • Rashes and lipoatrophy
  • Upper respiratory infection
  • Headaches
  • Muscle pain
  • Joint Pain, back pain
  • Carpal tunnel syndrome
  • Abdominal pain
  • Edema
  • Decreased or difficult urination

In rare instances, Norditropin Flexpro can cause more serious side effects. These can include:

  • Acute critical illness
  • Prader-Willi Syndrome in children – check for signs of upper airway obstruction and sleep apnea before initiation of treatment
  • Neoplasm
  • Impaired glucose tolerance, new or worsening high blood sugar (hyperglycemia), and Diabetes Mellitus
  • Intracranial Hypertension (increased blood pressure)
  • Serious hypersensitivity reactions
  • Fluid Retention
  • Hypoadrenalism – glucocorticoid dose increases in those with known hypoadrenalism
  • Hypothyroidism
  • Slipped capital femoral epiphysis – evaluate children with the onset of a limp or hip/knee pain
  • Progression of preexisting scoliosis
  • Pancreatitis
  • Leukemia

If you experience any of these serious side effects, stop taking Norditropin and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Norditropin?

Long-term side effects of Norditropin include an increased risk of the growth of a tumor already present and the increased risk of a tumor returning in those who have previously been treated as children and have low growth hormones.

What are the side effects of stopping Norditropin?

Stopping Norditropin treatment results in a child being shorter than they would be at adulthood if they had continued treatment. These patients will have weaker bones, less muscle, and higher body fat and cholesterol. They will also have psychological symptoms such as increased tiredness, reduced energy, irritability, and depression.

Norditropin dosage

Norditropin is available as a prefilled pen in the following doses:

  • 5 mg/1.5 mL (orange)
  • 10 mg/1.5 mL (blue)
  • 15 mg/1.5 mL (green)
  • 30 mg/3 mL (purple)

Norditropin should be given as a subcutaneous injection:

  • Pediatric GHD: 0.024 to 0.034 mg/kg/day, 6 to 7 times a week
  • Noonan Syndrome: Up to 0.066 mg/kg/day
  • Turner Syndrome: Up to 0.067 mg/kg/day
  • SGA: Up to 0.067 mg/kg/day
  • Adult GHD: 0.004 mg/kg/day, increased as tolerated to not more than 0.016 mg/kg/day after approximately 6 weeks, or a starting dose of approximately 0.2 mg/day (range, 0.15 to 0.30 mg/day) increased gradually every 1 to 2 months by increments of approximately 0.1 to 0.2 mg/day

Injection sites should always be rotated to avoid lipoatrophy. Do not expose your pen to dust, dirt, liquid, or direct light.

Please see the instructions for use in the prescribing information and drug information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What is the maximum recommended dose of Norditropin?

Your treatment and dose prescribed to you will depend on whether you are an adult or a child, the condition you are being treated for, and in the case of children, your body weight. The usual maximum daily dose is 1.0 mg per day, but this will be decided by your doctor and may be adjusted depending on your response to treatment.

How often does Norditropin need to be taken?

Norditropin should be used daily, every evening, just before bedtime.

Norditropin drug interactions

Norditropin can interact with other medications, including:

  • Cytochrome P450-metabolized drugs
  • Oral estrogen
  • Insulin and/or oral/injectable hypoglycemic agents

Before taking Norditropin Flexpro, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Norditropin warnings & precautions

You should not use Norditropin if you:

  • Are allergic to the active ingredient somatropin
  • Have had an allergic reaction to any of the other ingredients in Norditropin
  • Are pregnant or are planning to become pregnant
  • Have had a recent acute critical illness – open heart surgery, abdominal surgery, multiple accidental trauma or acute respiratory failure
  • Are a child with Prader-Willi syndrome who is severely obese or has severe respiratory impairment (Norditropin causes breathing problems)
  • Have active cancer
  • Have active proliferative or severe non-proliferative Diabetic Retinopathy

Talk to your doctor before using Norditropin if you:

  • Are taking any of the medications that could interact with Norditropin
  • Are breastfeeding or are planning to breastfeed
  • Have diabetes
  • Have a pituitary gland disorder
  • Have abnormal curvature of the spine (scoliosis)
  • Have an underactive thyroid

You should always check with your doctor or pharmacist before taking any medication, including Norditropin, to make sure it is safe for you.

What are the side effects of taking growth hormones?

Using high levels of growth hormone can produce irreversible acromegaly if used over a long period of time. However, smaller doses can lead to blood clots, heart disease and diabetes.

What are the side effects of giving a child growth hormones?

Side effects experienced in children include problems at the injection site, headaches, and hip problems. Long-term side effects may include an increased risk of the growth of a tumor already present and the increased risk of a tumor returning in those who have previously been treated.

What is the difference between growth hormones and steroids?

The first thing to know is that anabolic steroid use is against the law under all conditions, and illegal steroid use may cause serious and irreversible negative health impacts. Growth hormone therapy, in contrast, is a well-documented medical practice offering benefits to patients with growth hormone deficiencies. Speak to your doctor to discuss the safe treatments available to you.

How long does it take to see results from Norditropin?

Initial results may take up to 6 months to be seen, with the greatest results seen in the first year of use.

Can Norditropin cause a loss of appetite?

Norditropin may cause loss of appetite as well as symptoms of hunger. Speak to your healthcare provider if you experience either of these side effects.

Can Norditropin cause weight loss?

Norditropin can cause weight loss, with an increase in the proportion of weight lost as fat and visceral fat.

Does Norditropin cause mood swings?

Norditropin may cause changes in mood, specifically an increase in symptoms of anxiety and depression.

Does Norditropin cause fatigue?

Yes, fatigue is a common side effect when taking Norditropin. Speak to your healthcare provider if this side effect becomes excessive or detrimental to you.

How to avoid Norditropin side effects

The best way to avoid side effects is to take Norditropin as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Norditropin that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Norditropin. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Norditropin as it can increase your risk of feeling tired or lethargic and lead to respiratory depression, seizures and even death.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Norditropin.

7. Know the signs and symptoms of Norditropin side effects

Signs and symptoms of side effects include upper respiratory infections. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Norditropin may cause weight loss. If you experience this side effect while taking Norditropin, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Norditropin.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Norditropin as needed.

Vemlidy side effects and how to avoid them

Vemlidy is a brand-name medication manufactured by Gilead Sciences, Inc. It is classified as a nucleoside reverse transcriptase inhibitor (NRTIs) and is used for the treatment of chronic hepatitis B infection. While Vemlidy is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Vemlidy include headaches and tiredness. Less common but more serious side effects can include kidney problems. Learn more about the side effects of Vemlidy and what you can do to avoid them.

What is Vemlidy (tenofovir alafenamide)?

Vemlidy is a medicine prescribed to treat chronic hepatitis B infection in adults with liver damage. It helps to stop the virus from multiplying and spreading through your liver cells. This can lower the amount of virus in your body and improve the condition of your liver.

Hepatitis B is an infection of your liver caused by the hepatitis B virus. You catch the virus from an infected person’s body fluids, most often from sharing intravenous needles or through sex. When you first get the infection (the acute phase), you can feel symptoms like abdominal pain, fever, nausea and vomiting, tiredness, a yellow tinge to your skin, and dark urine. It can take some time for you to feel any symptoms, sometimes 30 to 180 days after you’re infected. Some people may feel no symptoms at all.

Most people recover from the initial infection and clear the virus from their bodies. But around 10% of people don’t clear the virus and develop a long-term infection (chronic phase). If you have a chronic hepatitis B infection, you likely won’t feel any symptoms, but the virus can damage your liver over time. This damage can lead to compensated liver disease, where your liver becomes scarred but still retains some to most of its function. If the liver damage progresses, it can result in cirrhosis (damage that leads to liver failure) and can cause liver cancer.

The hepatitis B virus copies itself and spreads through the cells of your liver. If it copies itself faster than your immune system can kill it, the virus persists and spreads and can damage your liver. Vemlidy helps with this by preventing the virus from copying itself. The active ingredient tenofovir alafenamide interrupts a key stage of the replication process where the virus copies its genetic code inside your cells. This stops the virus from spreading and can improve your liver function.

What are the side effects of Vemlidy?

The most common possible side effects of Vemlidy include:

  • Headaches
  • A cough
  • Nausea
  • Fatigue
  • Stomach pain
  • Back pain, joint pain (arthralgia)
  • Increased fasted low-density lipoprotein (LDL) cholesterol

In rare instances, Vemlidy can cause more serious side effects, including:

  • Severe allergic reactions – symptoms include rash, itching, swelling of the face, tongue, or throat, severe dizziness, and trouble breathing
  • A potentially life-threatening condition called lactic acidosis caused by a build-up of lactic acid in your blood
  • Liver problems – upper stomach pain, unusual tiredness, loss of appetite, clay-colored stools, dark urine, yellowing of the skin or eyes
  • New or worsening kidney problems, including kidney failure
  • Fanconi syndrome (type of kidney disease)
  • A worsening of your hepatitis B infection

If you experience any of these serious side effects, stop taking Vemlidy and seek medical attention immediately. You are encouraged to report adverse reactions of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Vemlidy dosage

Vemlidy is available in 25 mg tablets. Before starting treatment with Vemlidy, your doctor will check you do not have an HIV-1 infection.

Take Vemlidy once daily with food, at the same time each day. Do not miss taking Vemlidy. If you forget to take a dose, take it as soon as you remember, but skip the missed dose if it is almost time for your next dose. If you are receiving dialysis treatment, take your daily dose after your dialysis.

Store Vemlidy tablets in their original container at room temperature, away from moisture and heat. You are advised to read the complete medication guide provided with this medicine for drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How long do you take Vemlidy?

You will usually take Vemlidy for at least 6 to 12 months, but treatment may last several years. Speak to your doctor about your treatment plan if you have any questions.

Vemlidy drug interactions

Vemlidy can interact with other medications, including:

  • Any medicines that have tenofovir alafenamide, tenofovir disoproxil fumarate, or adefovir dipivoxil in them
  • Any antibiotics that have rifabutin, rifampin, or rifapentine in them
  • Antiviral medicines used to treat HIV, like ritonavir, lopinavir, or atazanavir
  • Anticonvulsants used to treat epilepsy, like carbamazepine, oxcarbazepine, phenobarbital, or phenytoin
  • Antifungal medicines, like ketoconazole or itraconazole
  • Herbal remedies used to treat depression and anxiety that contain St. John’s wort

Before taking Vemlidy, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Vemlidy warnings & precautions

  • Are allergic to the active ingredient tenofovir alafenamide
  • Are allergic to any of the other ingredients in Vemlidy
  • Are under 18 years of age

Talk to your doctor before taking Vemlidy if you:

  • Are taking any of the medications that could interact with Vemlidy (see the section above)
  • Have HIV/AIDS
  • Have a chronic kidney disease called end-stage renal disease (ESRD)
  • Have any other kidney problems
  • Have any other liver problems
  • Have hepatitis C or D
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk
  • Are lactose intolerant

You should always check with your doctor or pharmacist before taking any medication, including Vemlidy, to make sure it is safe for you.

Is Vemlidy safe?

Vemlidy may cause serious side effects such as worsening of the hepatitis B virus infection. Your doctor will monitor you and carry out blood tests while you are taking this medication to make sure it is safe for you.

Does Vemlidy cause hair loss?

Hair loss as a side effect has been reported in African American women aged 40 to 61.

Will Vemlidy cure your liver?

Vemlidy is used to treat chronic hepatitis B virus (HBV) in adults and will reduce the amount of HBV in your body. It may improve your liver condition.

Can Vemlidy cure hepatitis B?

Vemlidy will reduce levels of hepatitis B virus, and vaccines can prevent hepatitis B, but there is no cure for hepatitis B.

Can Vemlidy be used during pregnancy?

Vemlidy should only be used during pregnancy if the benefits outweigh the risks. Discuss your treatment options with your doctor before you start using Vemlidy if you are pregnant.

What happens when you stop taking Vemlidy?

Stopping treatment with Vemlidy may cause severe acute exacerbations of hepatitis B. This could potentially be life-threatening in patients with advanced liver disease or cirrhosis.

How to avoid Vemlidy side effects

The best way to avoid side effects is to take Vemlidy as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Vemlidy that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Vemlidy. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can worsen side effects.

4. Avoid alcohol

Avoid drinking alcohol while taking Vemlidy, as it can increase your risk of liver damage.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Vemlidy.

7. Know the signs and symptoms of Vemlidy side effects

Signs and symptoms of side effects include headaches and tiredness. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Vemlidy may cause weight gain. If you experience this side effect while taking Vemlidy, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Vemlidy.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Vemlidy as needed.

Alternatives to Adderall for ADHD

Adderall is an FDA-approved (U.S. Food and Drug Administration) brand-name medication manufactured by Shire US Inc. Adderall is a stimulant medication used to treat ADHD (attention deficit hyperactivity disorder) in children (ages 6-12), adolescents (ages 13-17), and adults.

Stimulant drugs, when used for the treatment of ADHD can help manage ADHD symptoms, such as a short attention span, impulsive behavior, and high energy levels (hyperactivity). Adderall is also approved to treat narcolepsy, a sleep disorder with excessive daytime sleepiness and episodes of sleep attacks.

The active ingredients in Adderall are amphetamine and dextroamphetamine. Adderall can become physically addictive and cause withdrawal symptoms when ADHD treatment is stopped.

Here, we will look at what Adderall is, how it works, its side effects, drug interactions, and contraindications, as well as the alternatives available over the counter and from your doctor on prescription.

How does Adderall work?

Adderall and Adderall XR contain amphetamine and dextroamphetamine, which belong to a drug class called central nervous system (CNS) stimulants. CNS stimulants help increase focus and alertness and decrease impulsivity. Adderall and Adderall XR are Schedule II controlled substances. This means they have the potential for abuse and dependence.

For someone with ADHD, Adderall boosts the levels of certain brain chemicals (also known as neurotransmitters), like dopamine and norepinephrine, helping to improve cognitive function and reduce mental tiredness.

Adderall dosage

Adderall is available as an immediate-release tablet formulation in the following doses: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg. It is also available in the extended-release (long-acting) form (Adderall XR) of a capsule in the following doses: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg.

Your daily dose will be based on your age:

  • Children aged 6-17 years of age – 10 mg once daily in the morning
  • Adults – 20 mg once daily in the morning

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the alternatives to Adderall for ADHD?

What works just as well as Adderall?

Alternative prescription medications available for the treatment of ADHD include:

Alternatives to Adderall XR include:

  • Concerta (methylphenidate)
  • Dexedrine (amphetamine)
  • Evekeo (amphetamine)
  • Focalin XR (dexmethylphenidate)
  • Quillivant XR (methylphenidate)
  • Ritalin (methylphenidate)
  • Strattera (atomoxetine hydrochloride)

What are the natural Adderall alternatives?

Natural alternatives to Adderall include:

  • Citicoline – these supplements may help reduce the symptoms of ADHD. They may also help with nervous system disorders such as dementia and glaucoma. Citicoline is the same as a precursor to phospholipid, which helps the brain to work normally and may also help repair brain damage. Citicoline does not appear to have side effects, however, it does require further testing as an alternative for the treatment of ADHD
  • Methionine – this is an amino acid used to help produce chemicals in the brain. It has been used for the treatment of ADHD and the symptoms of depression. Methionine may, however, cause an increase in manic episodes and anxiety in adult patients with bipolar disorder
  • Vitamin B-6 is used in the body to make serotonin, a chemical that helps to manage your mood and feelings. Vitamin B6, when given with magnesium supplements to children with ADHD was seen to improve symptoms of ADHD, such as mental focus, aggressive behavior, and hyperactivity after 8 weeks of treatment. These symptoms of ADHD were seen to return after treatment with these supplements was discontinued
  • Gamma-aminobutyric acid (GABA), a chemical found in the brain that reduces hyperactivity and excitability as well as anxiety and stress. GABA may be used to treat adults and children with ADHD and some mental health problems
  • Gingko Biloba – This is a herbal supplement used to help improve blood flow and memory in older adults. Gingko Biloba has also been found to help improve symptoms of ADHD in children. Further testing is needed however to ascertain its full benefits
  • Pycnogenol – This is an antioxidant that may help improve circulation, reduce blood pressure, reduce oxidative stress and inflammation, causing a reduction in the symptoms of ADHD. Pycnogenol supplements have been found to reduce the symptoms of hyperactivity in children, improve focus, hand-eye coordination, and concentration over a 4-week period. It’s not known if these same benefits are seen in adults with ADHD
  • Combination supplements containing a mix of herbs such as Humulus, Aesculus, Oenanthe, Aconite, Gelsemium, GABA, and L-Tyrosine. This combination supplement may help people to remain calm without feeling irritable or anxious
  • Natural supplements to help improve focus and memory may also help those with ADHD, these include:
    • Fish oils containing omega-3 fatty acids
    • Flax seeds also providing omega-3 fatty acids and other nutrients
    • Rosemary and mint for the improvement of memory and alertness
    • Cocoa seed, an antioxidant that protects the brain
    • Sesame seeds rich in tyrosine, vitamin B-6, zinc, and magnesium, which also help maintain brain health
    • Saffron for the improvement of brain function
  • Supplements containing iron, magnesium, and zinc may help reduce the symptoms of ADHD in children. Children without a mineral deficiency may not benefit from taking extra supplements

Speak to your healthcare provider for further advice before trying an alternative or changing your ADHD medication.

What is similar to Adderall over the counter?

The best nootropics, herbs, supplements, or OTC stimulants for ADHD include Ginkgo Biloba, Alpha GPC/Citicoline, Omega-3 Fatty Acids, Magnesium, Pycnogenol, NALT (N-Acetyl-L-Tyrosine) or Tyrosine, Valerian Root, and L-theanine.

Nootropics are natural or man-made supplements or drugs used to improve cognitive function and relaxation, boost mood, and improve attention, memory, creativity, and motivation in healthy people.

What alternatives are there to Adderall while pregnant?

Alternatives to Adderall during pregnancy that have fewer side effects include low-dose stimulant drugs such as amphetamine or caffeine or a non-stimulant drug such as napsine or modafinil. Vyvanse and Ritalin are not proven to be safe during pregnancy but are also not known to be harmful. Women taking ADHD treatment during early pregnancy may be at greater risk of having a baby with birth defects compared to those women who did not use ADHD treatment.

What alternatives are there to Adderall on prescription?

Alternatives to Adderall, only available on prescription, include Dexedrine (d-amphetamine), Vyvanse (lisdexamfetamine), Ritalin and Concerta (methylphenidate), Kapvay (clonidine), Intuniv (guanfacine), and Strattera (atomoxetine).

What stimulant is closest to Adderall?

The closest stimulants to Adderall are Focalin (dexmethylphenidate), Dexedrine (dextroamphetamine), or Ritalin and Concerta (methylphenidate).

What should I do if I can’t find Adderall?

If you can not find Adderall, speak to your doctor about switching to an alternative. You should not stop taking Adderall without speaking to your doctor first for medical advice.

What is generic Adderall?

Generic drugs are essentially the same as the branded versions. The generic equivalent will contain the same active ingredients as the branded version. In this case, the generic names for Adderall are amphetamine and dextroamphetamine. Generic drugs are reviewed and approved by the FDA in the same way branded drugs are.

What are the best Adderall alternatives?

Modafinil may be more effective for the treatment of the symptoms of ADHD. It is important to note that not all patients will respond to medications in the same way. What is an effective treatment for one patient may not be the same for another. Always speak to your doctor to decide which treatment is the best option for you.

Adderall side effects

The most common side effects of Adderall in clinical trials include the following:

  • Loss of appetite, abdominal pain, diarrhea, constipation, weight loss
  • Insomnia, changes in mood, anxiety
  • Vomiting, nausea, headaches, dizziness, dry mouth
  • Fast heart rate
  • Asthenia
  • Urinary tract infections

More serious side effects of Adderall include

  • Serious cardiovascular events
  • Increase in blood pressure
  • Psychiatric adverse events – may cause treatment-emergent psychotic or manic symptoms in patients with no prior history or worsening of symptoms in patients already suffering from psychosis
  • Long-term suppression of growth
  • Seizures
  • Peripheral vasculopathy, including Raynaud’s phenomenon
  • Visual disturbance
  • May exacerbate tics

You are encouraged to report the adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Adderall drug interactions

Adderall can interact with other medications. These include:

  • MAOI antidepressants
  • Alkalinizing and acidifying agents
  • Adrenergic blockers
  • Antihistamines
  • Antihypertensives
  • Tricyclic antidepressants – norepinephrine, and meperidine

Adderall can interact with other prescription medications. This can change how Adderall and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Adderall warnings & precautions

You should not use Adderall if you:

  • Are allergic to the active ingredient methylphenidate
  • Are allergic to any of the other ingredients in Concerta
  • Have known structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, coronary artery disease, or other serious heart problems
  • Have used an MAO inhibitor in the past 14 days, such as isocarboxazid, rasagiline, selegiline, or tranylcypromine
  • Are younger than 3 years old
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Adderall if you:

  • Have had problems with drug or alcohol abuse
  • Have a history of depression, mental illness, bipolar disorder, or suicidal thoughts or actions
  • Have glaucoma
  • Have an overactive thyroid
  • Have severe agitation
  • Have high blood pressure, heart disease, or coronary artery disease
  • Have vascular disease
  • Have motor tics or Tourette’s syndrome
  • Suffer from seizures
  • Have liver or kidney disease
  • Blood circulation problems in your hands or feet
  • Are pregnant or are planning to become pregnant

You should always check with your doctor or pharmacist before taking any medication, including Adderall, to make sure it is safe for you.

Alternatives to Synthroid: which other medications can I take?

Synthroid is an FDA (U.S. Food and Drug Administration) approved brand-name medication manufactured by AbbVie, Inc. Synthroid is used to replace the hormone that would normally be produced by your thyroid gland.

Synthroid is a commonly used thyroid medication; however, it may not be suitable for everyone, or there may be those who want to manage their condition naturally. Here, we will look at what Synthroid is, how it works, and what alternatives are available.

What is Synthroid (levothyroxine)?

Symptoms of low thyroid hormone levels include tiredness, muscle aches, constipation, dry skin, weight gain, slow heartbeat, or sensitivity to cold. Synthroid contains levothyroxine sodium as the active ingredient and is used:

  • As thyroid hormone replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism (underactive thyroid)
  • Alongside surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer
  • For the suppression of thyroid-stimulating hormone (TSH), this helps with the treatment of certain types of thyroid cancers and goiters

Synthroid is not recommended for the suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients or for the treatment of hypothyroidism during the recovery phase of subacute thyroiditis. Synthroid is also not for the treatment of obesity or weight loss.

Synthroid dosage

Synthroid is available in tablet form, in the following doses: 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200, and 300 mcg.

Synthroid is taken once daily, on an empty stomach, half to one hour before breakfast. You should take Synthroid at least 4 hours before or after drugs that are known to affect its absorption. Your starting dose will depend on a number of factors, including your age, body weight, cardiovascular status, and other medications you take.

If you forget to take a dose of this medication, take it as soon as you remember. If it is near the time of your next dose, skip the missed dose and take your next dose at the normal time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Synthroid side effects

The most common side effects of Synthroid include:

  • Irregular heartbeats, palpitations, myocardial infarction
  • Dyspnea
  • Muscle spasms, muscle weakness
  • Headache
  • Anxiety, irritability
  • Trouble sleeping, tiredness
  • Increased appetite, weight loss
  • Diarrhea
  • Intolerance to heat
  • Menstrual changes
  • Skin rash
  • Chest pain, shortness of breath
  • Partial hair loss

Synthroid can cause more serious side effects. These can include:

  • Cardiac adverse reactions in the elderly and in patients with underlying cardiovascular disease
  • Acute adrenal crisis in patients with concomitant adrenal insufficiency
  • Hyperthyroidism or incomplete treatment of hypothyroidism
  • Worsening of diabetic control
  • Decreased bone mineral density

Your doctor will assess the benefits of using Synthroid against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Synthroid to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Synthroid drug interactions

Synthroid can interact with other medications, including:

  • Cholestyramine, colestipol, colesevelam
  • Antacids
  • Sucralfate
  • Simethicone, iron, sodium polystyrene sulfonate
  • Calcium supplements
  • Orlistat, lanthanum, sevelamer
  • Certain medicines used to treat high cholesterol

This list is not exhaustive, and other prescription drugs may interact with Synthroid. Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.

What are some other medications that can replace Synthroid?

  • Cytomel contains liothyronine, a synthetic thyroid hormone ingredient. Regular blood tests will need to be done when using Cytomel as liothyronine is absorbed quicker by the body than levothyroxine, causing an increased risk of side effects
  • Thyrolar contains liotrix, a combination of synthetic T4 and T3. Thyrolar may be used to help supplement thyroid hormones for the treatment of hypothyroidism
  • Levoxyl, Unithroid, and Tirosint are alternative branded versions of levothyroxine. These are FDA approved for the treatment of hypothyroidism and the suppression of TSH for thyroid cancers, euthyroid goiters, and other thyroid problems.

What are some natural thyroid alternatives to Synthroid?

  • Armour Thyroid is a dried thyroid extract from animal thyroid glands (porcine/pig). Armour thyroid contains thyroxine (T4) and triiodothyronine (T3) and is used to treat hypothyroidism and thyroid cancer. Armour Thyroid is not FDA-approved but may still be recommended as a treatment option. Hypothyroid patients report better results after using Armour Thyroid compared to using levothyroxine, despite an increased risk of side effects
  • Selenium is thought to play an essential part in thyroid functions. Low selenium levels are associated with thyroid diseases, such as hypothyroidism and ensuring levels of selenium are maintained at the correct level may help to reduce thyroid problems. Further clinical trials are required however, to assess how effective selenium is at reducing this risk
  • Low levels of vitamin B12 may be linked to problems with the thyroid gland, including autoimmune thyroid diseases, such as Hashimoto’s disease and hypothyroidism. vitamin B12 may help to maintain thyroid function
  • Vitamin D is taken with calcium to maintain the proper development of bones. Low Vitamin D levels have also been shown to be linked to thyroid disease and taking vitamin D may help to manage thyroid problems in those taking levothyroxine
  • Essential oils are thought to help manage the symptoms of hypothyroidism. These include lavender, peppermint, rosemary, sandalwood, and lemongrass. Clinical trials are required to confirm this
  • Herbal remedies may be used to maintain healthy thyroid hormone levels. Herbal remedies, however, are not FDA-approved and have not been tested in the same way as treatments your doctor may prescribe. Examples of herbal remedies include Bladderwrack, a type of seaweed containing iodine, minerals, and dietary fibers, and Ashwagandha root extract, which may have some benefits for thyroid hormone levels
  • A healthy, well-balanced diet containing fruits, vegetables, whole grains, and lean proteins can help to maintain a healthy endocrine system
  • Weight gain and a slow metabolic rate are common when you have hypothyroidism. Your doctor may recommend an increase in physical activity to help you manage your weight gain or obesity. Exercises such as swimming, walking, or jogging may be useful
  • Managing stress may help to regulate your thyroid hormone levels. Try yoga or meditation, and other relaxation methods to help reduce your stress

US Fertility Report

Which states have caught ‘baby fever’?

As the cost of living continues to rise, it is more important than ever for US residents to find affordable medication online – from Trintellix to Trulicity and everything in between!

During the COVID-19 pandemic, communities came together to support each other and this emphasized the value of family. Subsequently, it has inspired Americans to think about having children of their own. Having said this, the concept of fertility is complex and differs from one person to another.

Here at NiceRx, we were curious about all things fertility in the US – which state has the most fertility clinics? Who has the highest fertility rate? Where are people searching about it the most? Look no further as we have the answers!

States with the highest fertility rates

 

To kick off our fertility report we have ranked each US state based on who has the highest fertility rate using data from 2022. For the purpose of this list, ‘fertility rate’ is determined by the number of births per 1,000 women.

1. South Dakota – 73.6 Fertility Rate

In terms of the highest US fertility rate, South Dakota takes the top spot with 73.6 babies being born per 1,000 women. Based on the fact that this state is known for having one of the strongest economies and quality of life, it’s no surprise that the residents here are keen to increase the size of their families!

2. North Dakota – 72.2 Fertility Rate

With a low cost of living and a low crime rate, the state of North Dakota is characterized by features indicative of a child-friendly environment. Moreover, with a fertility rate of 72.2, it falls just short of its southern neighbors making it the second most fertile state in the US.

3. Alaska – 69.3 Fertility Rate

Since the implementation of Alaska’s ‘Permanent Fund Dividend’, which annually pays out money to every resident living in the state, they have seen an increase in their fertility rate. As of 2022, Alaska’s fertility rate stands at 69.3, which is the third highest in the US.

 

All states with the highest feritility rates

 

Sates with the most fertility clinics

 

We were also interested in finding out where the hotspots are in terms of fertility clinics. As a result, we have collated a list of the US states with the most fertility clinics, making it easy for you to see where your state stands in the rankings!

1. Hawaii – 3.73 fertility clinics per 1,000,000 residents

Despite not having the highest total number of fertility clinics when compared to other states, Hawaii takes the top spot in terms of the number of clinics per 1,000,000 residents. This finding suggests that this state perceives fertility as an important factor, thus they have a range of facilities to cater to this.

2. Vermont – 2.46 fertility clinics per 1,000,000 residents

Vermont comes in at number two with 2.46 fertility clinics per 1,000,000 residents. One of the common factors associated with infertility is age, and as a state with a large percentage of over 35-year-olds, it suggests that Vermont residents are among the demographic who are likely to seek fertility-related assistance.

3. North Dakota – 1.30 fertility clinics per 1,000,000 residents

In a similar fashion to the above list, North Dakota has also appeared in this ranking – with 1.30 fertility clinics per 1,000,000 residents. As it was previously revealed, this state has the second-highest fertility rate, and this could be a result of its abundance of fertility clinics.

 

All states with the most fertility clinics

 

States searching the most about fertility

 

As well as looking at which states are currently the most fertile, we also wanted to find out who is the most interested in learning about fertility. We did this by analyzing Google search data over the last 12 months and factoring in population differences.

1. North Dakota – 329 Searches per 100,000 Residents

Even though North Dakota has fewer overall Google searches than other states in this list, it takes the top spot in terms of the number of searches per 100,000 residents. Making an appearance in every top three list so far, it seems that the residents of North Dakota have a keen interest in anything fertility-related!

2. Mississippi – 322 Searches per 100,000 Residents

Despite not making the top ten list of states with the highest fertility rates, Mississippi does have the second most fertility-related searches. Residents here may not be having children at the same rate as other states, but they are actively researching different treatments and advice which demonstrates a potential interest in having children in the future.

3. Hawaii – 304 Searches per 100,000 Residents

Completing this top three list is Hawaii with 304 Google searches per 100,000 residents. As revealed earlier in this report, this state also has an abundance of fertility clinics which may explain why the residents here are keen to research this topic.

 

Most popular fertility search questions

As well as finding out which states in America are currently searching the most about fertility, it is also interesting to see what US residents are searching for when it comes to this topic.

Below is a list of the most popular fertility-based questions searched in the US between 2021-2022.

Methodology

We used 2022 data from World Population Review to find the fertility rate for each US state.

We used data from CDC to determine the number of fertility clinics in each US state as of 2022. By dividing the total number of fertility clinics by the population for each state and multiplying this number by 1,000,000 we were able to calculate the number of fertility clinics per 1,000,000 residents.

We used the Keywords Explorer feature on AhRefs to collect a range of fertility-related questions. We then used Google Keyword Planner to add up the total number of fertility question searches for each state between Oct 2021 and Sept 2022 as well as the population for each state. By dividing the total number of searches by the population for each state and multiplying this number by 100,000, we were able to calculate the number of searches per 100,000 residents.

Bydureon side effects and how to avoid them

Bydureon is an FDA-approved brand-name diabetes medication manufactured by AstraZeneca. It is classified as a glucagon-like peptide-1 agonist and is used to help control blood sugar levels in patients with type 2 diabetes. While Bydureon is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Bydureon include injection site reactions. Less common but more serious side effects can include thyroid tumors.

Learn more about the side effects of Bydureon and what you can do to avoid them.

What is Bydureon (exenatide)?

Bydureon is used to help control blood sugar levels in type 2 diabetes, a condition where the body is unable to produce enough insulin or does not respond to the insulin made as it normally would. This can lead to high blood sugar levels. Bydureon may be used alone or in combination with other medications, such as metformin or long-acting insulin. Bydureon may also be used for the treatment of Parkinson’s and also as a weight-loss therapy.

Exenatide, the active ingredient, is classed as an incretin mimetic and is used alongside diet and exercise in diabetes. Incretins such as glucagon-like-peptide-1 (GLP-1), improve insulin release that is dependent on blood glucose. Exenatide is a GLP-1 receptor agonist and has been shown in lab tests to attach to and stimulate the human GLP-1 receptor. This increases glucose-dependent insulin production from the pancreas as well as the release of insulin from pancreatic beta-cells. Exenatide also slows the time it takes for food to empty from the stomach. This combined action enables exenatide to help control blood glucose levels.

Bydureon BCise is not recommended to be used in people with type 1 diabetes.

What are the side effects of Bydureon Bcise?

The most common possible side effects of Bydureon include:

  • Nausea, vomiting
  • Gastrointestinal side effects – diarrhea, constipation, abdominal pain, and indigestion
  • Headache
  • Injection site reactions – with or without bumps (nodules)
  • Skin abscess (a bump within or below the surface of your skin)

More serious side effects of Bydureon include:

  • Unusual bleeding or bruising
  • Severe nausea and vomiting
  • Life-threatening allergic reactions – swelling in your neck or throat, difficulty breathing or swallowing
  • Pain in your upper stomach spreading to your back, fever, increased heart rate, yellow color to eyes or skin
  • Hypoglycemia (low blood sugar) – headache, dizziness, sweating, confusion or drowsiness, blurred vision, slurred speech, fast heartbeat, anxiety, and mood changes
  • Painful, difficult, or low urination, swelling in your feet or ankles, tiredness or shortness of breath

If you experience any of these serious side effects, stop taking Bydureon and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Bydureon drug interactions

Bydureon can interact with other medications, including:

  • Treatments for skin cancer
  • Treatments for HIV/AIDS
  • Diuretics, taken to treat high blood pressure
  • Steroid treatment
  • Treatment for hypertension
  • Anti-coagulants – warfarin
  • ACE (angiotensin-converting enzyme) inhibitors
  • Sulfonylureas – glyburide, gliclazide, glipizide
  • Antibiotics

Bydureon can interact with other medications. This can change how Bydureon and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Bydureon warnings & precautions

You should not use Bydureon if you:

  • Are allergic to the active ingredient exenatide
  • Have had an allergic reaction to any of the other ingredients in Bydureon
  • Have a personal or family history of thyroid cancer
  • Or your family members have ever had medullary thyroid carcinoma (MTC)
  • Have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Have a history of low platelets (thrombocytopenia) while using exenatide
  • Are younger than 18 years of age

Talk to your doctor before using Bydureon if you:

  • Are taking any of the medications that could interact with Bydureon
  • Have kidney disease, have had a kidney transplant, or any other kidney problems
  • Have slowed emptying of your stomach (gastroparesis)
  • Have pancreatitis
  • Have gall stones
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Bydureon, to make sure it is safe for you.

Bydureon dosage

Bydureon is available as an exenatide extended-release injectable suspension in the following forms:

  • 2 mg of exenatide in single-dose vials
  • Single-dose pens auto-injector containing 2 mg of exenatide

Bydureon BCise is given as an injection under your skin (subcutaneous) in the stomach, thighs, or upper arm area, usually once every 7 days. Bydureon can be used with or without food and given at any time of the day. If you forget to take Bydureon, take it as soon as you remember, but skip the missed dose if your next dose is due within 3 days. Do not double up your doses.

Low blood sugar can make you hungry, dizzy, or shaky. To treat hypoglycemia, eat or drink candy, raisins, or non-diet soda. Your healthcare provider may prescribe glucagon tablets or injections in case of severe hypoglycemia. Refrigerate Bydureon and use until the expiration date. Do not freeze Bydureon. Bydureon may also be stored at room temperature for up to 4 weeks.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How long can you stay on Bydureon?

Bydureon is used once every 7 days. After 10 weeks of once-weekly continued use, Bydureon will maintain a consistent level of medicine in your body.

What are the dangers of taking Bydureon?

Bydureon may cause serious side effects such as thyroid tumors. Speak to your doctor if you get any swelling in your neck, have problems swallowing, or have shortness of breath.

Does Bydureon cause lumps in your throat?

Bydureon may cause symptoms of a thyroid tumor. Symptoms may include a lump in your neck, difficulty swallowing, trouble breathing, and changes to your voice. Speak to your doctor for medical advice if you experience these side effects.

Does Bydureon cause weight gain?

No. Bydureon may cause you to have a decrease in your appetite, causing you to potentially lose weight.

Does Bydureon cause hair loss?

Hair loss is a side effect of using Bydureon. This is most common in females over the age of 60 who have been taking Bydureon for 1 – 6 months.

What happens when you stop taking Bydureon?

Bydureon does not cause withdrawal reactions when you stop treatment. However, blood sugar levels may rise over time once you stop using it.

Does Bydureon cause tingling or numbness?

Bydureon may cause tingling and numbness in your lips if you become hypoglycemic (low blood sugar levels). Other symptoms of hypoglycemia will include hunger, confusion, and feeling weak and shaky. Contact your doctor if you experience these symptoms, as you may need to have your dose of Bydureon adjusted.

Is Bydureon a blood thinner?

Bydureon is not a blood thinner; it is classed as a glucagon-like peptide-1 (GLP-1) agonist. Bydureon increases how much insulin your pancreas produces in your body, causing blood sugar levels to fall.

What is the difference between Bydureon and Byetta?

Bydureon and Byetta both contain exenatide. Byetta is a short-acting version of exenatide, and Bydureon is the extended-release form. Byetta is used to treat adults only with Type 2 diabetes, while Bydureon is used in adults and children 10 years of age and older.

Is it safe to take Bydureon if you have diabetes?

Bydureon is used in combination with changes to diet and exercise to help manage blood sugar levels in Type 2 diabetes in adults and children 10 years of age and older.

How to avoid Bydureon side effects

The best way to avoid side effects is to take Bydureon as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Bydureon that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Bydureon. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid excessive alcohol consumption while taking Bydureon. Alcohol can increase your chances of developing low blood sugar, and excessive alcohol consumption could increase the risk of side effects from using Bydureon. Speak to your healthcare provider for further guidance on alcohol consumption when using Bydureon.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Bydureon.

7. Know the signs and symptoms of Bydureon side effects

Signs and symptoms of side effects include nausea and vomiting. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Bydureon may cause weight loss due to a loss of appetite. If you experience this side effect while taking Bydureon, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Bydureon.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Bydureon as needed.

Afinitor side effects and how to avoid them

Afinitor is an FDA-approved brand-name medication manufactured by Novartis. It is classified as a kinase inhibitor and is used for cancer treatment. While Afinitor is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Afinitor include joint pain and tiredness. Less common but more serious side effects can include kidney failure.

Learn more about the side effects of Afinitor and what you can do to avoid them.

What is Afinitor (everolimus)?

Afinitor is a kinase inhibitor used to treat:

  • Postmenopausal women with advanced breast cancer in combination with exemestane after treatment with letrozole or anastrozole have failed
  • Adults with progressive neuroendocrine tumors of the pancreas and adults with progressive, well-differentiated, non-functional neuroendocrine tumors of gastrointestinal or lung origin that are unresectable, locally advanced, or metastatic
  • Adults with advanced renal cell carcinoma (kidney cancer), after treatment with sunitinib or sorafenib, have failed
  • Adults with renal angiomyolipoma and tuberous sclerosis complex (TSC) not requiring immediate surgery

Afinitor dosage

Afinitor is available in tablet form in the following doses: 2.5 mg, 5 mg, 7.5 mg, and 10 mg. It is also available as Afinitor Disperz for oral suspension in the following doses: 2 mg, 3 mg, and 5 mg.

Afinitor and Afinitor Disperz should not be used together to achieve the daily dose.

  • Breast cancer – 10 mg orally once daily
  • Non-functional neuroendocrine tumors – 10 mg orally once daily
  • Advanced renal cell carcinoma – 10 mg orally once daily
  • TSC-Associated Renal Angiomyolipoma – 10 mg orally once daily
  • TSC-Associated SEGA – 4.5 mg/m2 orally once daily
  • TSC-Associated Partial-Onset Seizures – 5 mg/m2 orally once daily

Modify the dose for patients with hepatic impairment or for patients taking drugs that inhibit or induce P-glycoprotein (P-gp) and CYP3A4.

If you forget to take your medicine, take it as soon as you remember. If more than 6 hours have passed since you took your last dose, skip the missed dose and take your next dose at the usual time. Store Afinitor in the original container at room temperature, away from light and moisture.

You are advised to read the medication guide provided with this medicine for drug information and patient information. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the most common side effects of Afinitor?

The most common side effects of Afinitor include the following:

  • Stomatitis – use dexamethasone alcohol-free mouthwash when starting treatment
  • Dry mouth, mouth sores, or mouth ulcers
  • Signs of infection – fever, chills, tiredness, joint pain, skin rash, dry skin
  • Nosebleeds
  • Edema
  • Abdominal pain, decreased appetite, weight loss, diarrhea, nausea
  • Asthenia
  • Cough, sore throat, headache
  • High blood sugar
  • High cholesterol and triglycerides

What are the long-term side effects of Afinitor?

Afinitor can cause more serious long-term side effects, including:

  • Lung problems, such as shortness of breath, trouble breathing, and chest pain
  • Non-Infectious pneumonitis
  • Life-threatening hypersensitivity reactions
  • Angioedema
  • Increased blood pressure
  • Kidney failure
  • Impaired wound healing
  • Metabolic disorders – monitor serum glucose and lipids before and during treatment
  • Myelosuppression
  • Decreased red blood cells, white blood cells, and platelets
  • May rarely cause serious liver disease in people who have hepatitis B virus. Symptoms of liver damage include dark urine, persistent nausea and vomiting, loss of appetite, abdominal pain, and yellow eyes and skin

If you experience any of these serious side effects, stop taking Afinitor and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Afinitor drug interactions

Afinitor can interact with other medications, including:

  • Other drugs that weaken the immune system – natalizumab, rituximab
  • ACE inhibitors – captopril, lisinopril
  • Azole antifungals – itraconazole, ketoconazole
  • Macrolide antibiotics – clarithromycin, erythromycin
  • St. John’s wort
  • Risk of infection or reduced immune response with vaccination. Avoid live vaccines and close contact with those who have received live vaccines
  • Grapefruit or drinking grapefruit juice

This list is not exhaustive, and other prescription drugs may interact with Afinitor Disperz. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Afinitor warnings & precautions

Don’t take Afinitor if you:

  • Are allergic to the active ingredient everolimus or to other rapamycin derivatives such as sirolimus and temsirolimus
  • Have had an allergic reaction to any of the other ingredients in Afinitor
  • Are pregnant or are planning to become pregnant – Embryo-fetal toxicity (can cause harm to an unborn baby). Female patients are advised to use birth control during treatment and for at least 8 weeks after the last dose

Talk to your doctor before using Afinitor if you:

  • Are taking any of the medications that could interact with Afinitor
  • Have any kidney problems
  • Have liver problems
  • Are breastfeeding or are planning to breastfeed – It’s not known if this drug passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Afinitor, to make sure it is safe for you.

What Foods should I avoid while taking Afinitor?

Grapefruit juice may increase blood levels of Afinitor. Do not drink grapefruit juice or eat grapefruits while receiving treatment with Afinitor.

What is my Life expectancy on Afinitor?

Afinitor treatment has not been shown to increase life expectancy.

Is Afinitor chemotherapy?

Afinitor is not a type of chemotherapy. Afinitor is classed as a mammalian target of rapamycin (mTOR) inhibitor and is a targeted therapy that works by specifically targeting and attacking cancer cells. Chemotherapy attacks fast-replicating cells in the body but may also attack healthy non-cancerous cells.

Does Afinitor cause hair loss?

Afinitor does not cause hair loss when taken by itself but may be a side effect when taken with exemestane to treat certain types of cancer.

Does Afinitor cause breast cancer?

Afinitor does not casue breast cancer. Afinitor is used to treat patients with advanced hormone receptor-positive, HER2-negative breast cancer, in combination with exemestane, in women who have tried other medications unsuccessfully.

Can Afinitor shrink tumors?

Afinitor does help to shrink tumors. The degree to which Afinitor can do this will depend on the type of cancer being treated.

How long can you stay on Afinitor?

Afinitor may be used as a long-term treatment. The average treatment time was around 6 months, but could be as long as 2 years.

Can you take Afinitor with erythromycin?

Afinitor must be used with caution in patients also using CYP3A4 and/or PgP inhibitors such as erythromycin. The dose of Afinitor may need to be reduced to 2.5 mg when used in combination with erythromycin.

How much does Afinitor cost?

Without insurance, Afinitor Disperz costs will vary depending on where you buy the medication, as prices will vary by retailer. As a guide, Afinitor Disperz oral tablets 2 mg will cost around $15,750 for 28 tablets.

How to avoid Afinitor side effects

The best way to avoid side effects is to take Afinitor as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Afinitor that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Afinitor. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is not known to affect Afinitor treatment but may worsen side effects of Afinitor such as mouth sores or nausea, and diarrhea. Speak to your doctor for advice on what is a safe amount of alcohol to drink while also taking Afinitor.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Afinitor.

7. Know the signs and symptoms of Afinitor side effects

Signs and symptoms of side effects include mouth sores, joint pain, and tiredness. If you experience any of these symptoms, speak to your doctor for medical advice.

8. Monitor your weight

Afinitor may cause weight loss. If you experience this side effect while taking Afinitor, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Afinitor.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Afinitor as needed.

Xiidra side effects and how to avoid them

Xiidra is an FDA-approved brand-name medication manufactured by Novartis and used to treat dry eye syndrome. While Xiidra is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Xiidra include eye irritation and blurred vision. Less common but more serious side effects can include serious allergic reactions.

Learn more about the side effects of Xiidra and what you can do to avoid them.

What is Xiidra (lifitegrast)?

Xiidra (lifitegrast ophthalmic solution) is a lymphocyte function-associated antigen-1 (LFA-1) antagonist used to treat the signs and symptoms of dry eye disease (DED) in adults. With dry eye disease, you do not make enough tears, causing discomfort, burning, pain in your eyes, or blurry vision.

Exactly how Xiidra works for dry eye disease is not known but is thought to work on your immune system by blocking a specific protein (LFA-1) from attaching to certain cells. This helps reduce inflammation and increase tear production in those with chronic dry eyes.

More information on What is Xiidra

What is the most common side effect of Xiidra?

The most common possible side effects of Xiidra include:

  • Eye irritation
  • Eye discomfort
  • Blurred vision or other changes in vision
  • Eye redness
  • Unusual taste sensation (dysgeusia)
  • Headache
  • Increased tear production
  • Sinus infection

Xiidra can cause more serious side effects, including:

  • Allergic reactions (hives, swelling of the face or throat, and difficulty breathing)

If you experience any of these serious side effects, stop taking Xiidra and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Xiidra?

Long-term side effects of Xiidra include blurry vision, headache, eye irritation, dysgeusia (change in taste), red eyes, sinusitis (sinus infection), and watery eyes.

Does Xiidra have any side effects for pregnant women?

There is no data on the use of Xiidra in pregnant women or if it is found in breast milk during lactation. Since it is poorly absorbed into the bloodstream, the unborn baby or breastfed infant will more than likely not be exposed to the medication. Discuss the risks and benefits of using Xiidra with your healthcare provider if you are pregnant, plan on becoming pregnant, or are breastfeeding.

How often should you take Xiidra?

Xiidra is available as a preservative-free ophthalmic solution in the following doses: 5% (50 mg/mL). Use Xiidra in the affected eye(s) twice daily as directed by your doctor. To apply the eye drops, wash your hands thoroughly first. Do not allow the tip of the single-use container to touch your eye to prevent the risk of infection.

Do not use Xiidra eye drops if you wear contact lenses, and wait at least 15 minutes after using the eye drops before putting in your contact lenses. You may continue to use artificial tears with Xiidra if you need to do so. If you forget to use Xiidra, use it as soon as possible. If it is almost time for your next dose, skip the missed dose, and use your next dose at the normal time. Your healthcare provider may prescribe Restasis (cyclosporine) with Xiidra to help treat your dry eye syndrome.

Store Xiidra at room temperature away from heat, light, or moisture, and keep Xiidra in its original foil pouch until you are ready to use it.

Please read the prescribing information and drug information, and always speak with your eye doctor for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Xiidra drug interactions

Xiidra and Restasis can interact with other prescription medications. This can change how Xiidra and Restasis, and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including over-the-counter (OTC), vitamins, and dietary supplements.

Who should not use Xiidra?

You should not use Xiidra if you:

  • Have known hypersensitivity to the active ingredient lifitegrast
  • Have had an allergic reaction to any of the other ingredients in Xiidra

Talk to your doctor before using Xiidra if you:

  • Are taking any of the medications that could interact with Xiidra
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known whether lifitegrast ophthalmic passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Xiidra, to make sure it is safe for you.

Can you just stop taking Xiidra?

Do not stop using Xiidra without speaking to your doctor first. If you stop using Xiidra, dryness in your eyes may come back.

How long can you stay on Xiidra?

You should continue to use Xiidra for as long as your doctor prescribes it, as long as you are not suffering from any serious side effects. It should be noted that the safety of using Xiidra 12 months or longer isn’t known.

Does Xiidra cause a bad taste?

In clinical studies of Xiidra, patients reported dysgeusia, which causes people to have a salty or metallic taste in the mouth. Talk to your healthcare provider about ways to reduce these side effects.

Does Xiidra cause hair loss?

No, Xiidra is not reported to cause hair loss.

Can Xiidra damage your eyes?

Xiidra is not known to damage your eyes. Blurred vision or eye discomfort may occur when you use Xiidra, but these side effects should not be permanent. If these symptoms do not go away or if your vision becomes worse, speak to your healthcare provider immediately for medical advice.

Do Xiidra side effects go away?

Side effects from using Xiidra normally go away as your body adjusts to the treatment. Also, your healthcare provider will be able to advise you on ways to stop or reduce these side effects.

How to avoid Xiidra side effects

The best way to avoid side effects is to take Xiidra as directed by your doctor. Follow your doctor’s instructions carefully, and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Xiidra that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Xiidra. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can worsen side effects.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Xiidra.

6. Know the signs and symptoms of Xiidra side effects

Signs and symptoms of side effects include eye irritation and discomfort. If you experience any of these symptoms, speak to your doctor for medical advice.

7. Monitor your weight

Xiidra has been reported to cause some weight gain in a very few number of people using it. If you experience weight gain while taking Xiidra, get medical advice from your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Xiidra.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Xiidra as needed.

Alternatives to Prolia

Prolia is an FDA-approved brand-name medication manufactured by Amgen Inc. used to treat bone loss and osteoporosis (a weakening of the bones). Prolia is used specifically to treat:

  • Postmenopausal osteoporosis in women who have a high risk of bone fractures
  • Osteoporosis in men who have a high risk of bone fractures
  • Bone loss in women who are receiving adjuvant aromatase inhibitor hormone therapy for breast cancer
  • Bone loss in men who are receiving androgen deprivation therapy (ADT) for prostate cancer

Prolia is not recommended to treat osteopenia. Osteopenia is a condition where your bones are not as strong as normal but also not as weak as they would be if you had osteoporosis.

Here, we will look at what Prolia is, how it works, its side effects, and some of the alternative treatments available.

How does Prolia work?

Bone is a living tissue that needs to be maintained by your body. Certain conditions can interfere with this and can affect the health of your bones. This can lead to bone loss, and a condition called osteoporosis. Osteoporosis is a weakening of your bones that makes them more likely to have hip and vertebral fractures. It’s caused by having low bone density or by losing too much bone mass.

The hormones estrogen and testosterone help keep your bones healthy. Menopause can cause estrogen levels to fall in women, as can certain hormone therapies. This can lead to bone loss and osteoporosis. Likewise, declines in testosterone in men, such as those caused by prostate cancer treatments, can also result in bone loss and osteoporosis.

The active ingredient in Prolia is called denosumab. It helps counter bone loss and osteoporosis by reducing the rate at which your body loses bone tissue. Your body continually replaces old bone tissue with new bone tissue. Part of this process of bone turnover involves a protein called RANKL that helps produce a type of cell that breaks down bone. Denosumab works by blocking RANKL, stopping it from producing the cells that break down bone. This reduces the rate at which your body removes bone tissue, causing the bone mass to increase over time.

What is the most common side effect of Prolia?

The most common possible side effects of Prolia in clinical trials include:

  • Arm and leg pain
  • Bone and joint pain
  • Muscle pain
  • Hair loss
  • Constipation
  • Skin rashes and eczema
  • Frequent and painful urination
  • Blood in the urine

Prolia can cause more serious side effects, including:

  • Allergic reactions
  • Skin infections
  • Other serious infections
  • Jaw bone damage (osteonecrosis of the jaw)
  • Low calcium levels in the blood. Prolia is recommended in combination with calcium and vitamin D supplements.
  • Unusual fractures of the thigh bone

You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Prolia warnings & precautions

Don’t take Prolia if you:

  • Are allergic to the active ingredient denosumab
  • Are allergic to any of the other ingredients in Prolia (these are listed in the leaflet which comes with the medication)
  • Have low calcium levels in your blood (hypocalcemia)
  • Are under 18 years of age

Talk to your physician before taking Prolia if you:

  • Have cancer
  • Have ever had severe kidney problems, kidney failure, or have been on dialysis
  • Have poor dental health or any problems with your teeth or mouth, like gum disease
  • Are going to have a tooth extracted
  • Are a smoker (this can increase the risk of dental problems)
  • Have an allergy to latex (the cover of the pre-filled syringe contains a derivative of latex)
  • Are pregnant or trying to become pregnant
  • Are breastfeeding or plan to breastfeed

You should always check with your healthcare provider before taking any medication, including Prolia, to make sure it is safe for you. Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Prolia.

Is taking Prolia worth the risk?

The National Women’s Health Network recommends that Prolia only be used as a treatment option in post-menopausal women suffering from severe osteoporosis or when other osteoporosis medications have not worked. Prolia has an extensive list of side effects. However, not all the side effects of Prolia from long-term use are known and it is not clear if the benefits of using Prolia outweigh its risks.

What drug is equal to Prolia?

There are other osteoporosis drugs available for the treatment and/or prevention of osteoporosis, such as Reclast (zoledronic acid), Boniva (ibandronate), Fosamax (alendronate), Evenity (romosozumab), Evista (raloxifene), Miacalcin (calcitonin), and Forteo (teriparatide) or Tymlos (abaloparatide), which are based on parathyroid hormone (PTH) and are often used to treat severe osteoporosis.

What is the safest drug for osteoporosis?

Bisphosphonates such as Reclast, Fosamax, and Actonel (risedronate) are the first choice for osteoporosis treatment. Fosamax is taken as a once-weekly pill. Actonel is taken as a once-weekly or monthly pill. Reclast is given intravenously.

Is Reclast Better than Prolia?

In studies, Prolia was seen to have a greater increase in spine bone mineral density/BMD (a measure of bone health) at 1 year than Reclast, but not significantly. Reclast also had a greater incidence of causing mild flu-like symptoms. Prolia is a relatively new medication, and patient numbers for the study were relatively low. Further studies are needed to investigate the efficacy of Prolia.

What is the difference between Actonel and Prolia?

Prolia and Actonel are both used for the treatment of osteoporosis in women at high risk of bone fracture after menopause. Actonel may also be used for the treatment or prevention of osteoporosis in men and for the treatment of Paget’s disease of bone. Prolia is classed as a monoclonal antibody, and Actonel is classed as a bisphosphonate.

Is Prolia a cancer drug?

Prolia is a targeted drug treatment and is used for the treatment of secondary bone cancer. Prolia also helps to strengthen bones for certain types of cancer. Prolia is also used to increase low bone mass in patients with prostate cancer or breast cancer who are at high risk of fractures.

Prolia Dosage

Prolia is available in solution form in the following doses: prefilled syringes containing 60 mg in 1 mL or single-use vials containing 60 mg in 1 mL.

Prolia is given by a healthcare professional as a subcutaneous injection every 6 months in the upper arm, upper thigh, or abdomen. Patients are advised to take calcium 1000 mg each day and at 400 IU of vitamin D each day.

Victoza alternatives: which other diabetes medications can I take?

Victoza is manufactured by Novo Nordisk. It has FDA approval to help control blood sugar levels in people with type 2 diabetes (adult-onset diabetes) and is usually prescribed when people can’t control their blood sugar through diet and exercise alone or if their diabetes medication isn’t effective.

Here, we will take a look at what Victoza is, what its used for, how it works, and what alternative treatments are available.

What is Victoza used for?

Victoza can be used instead of other diabetes medicine or alongside some diabetes medicines. Victoza (liraglutide) is used:

  • As an adjunct to a reduced-calorie diet and increased physical activity to improve glycemic control in patients 10 years of age and older with type 2 diabetes mellitus
  • To reduce the risk of serious adverse cardiovascular events in adults with type 2 diabetes mellitus and known heart disease

Victoza is not approved by the FDA to treat type 1 diabetes mellitus. Using Victoza may aid weight loss and help to reduce body weight. This may be especially useful in those patients also suffering from obesity.

RELATED: What is Victoza

How does Victoza work?

When you eat and digest food, sugar is released into your blood so it can be transported around your body. Your body absorbs the sugar out of your blood, returning your blood sugar to normal levels. People with diabetes struggle to control their blood sugar and often have high blood sugar levels (hyperglycemia). Over time this can cause a range of problems, including nerve damage and heart disease.

Victoza is classed as a glucagon-like peptide-1 (GLP-1) receptor agonist that binds and activates the GLP-1 receptor in your pancreas. GLP-1 is an essential hormone that helps manage blood glucose levels after you eat carbohydrates or fats. In type 2 diabetic patients, GLP-1 levels are decreased. By activating the GLP-1 receptor, Victoza increases the release of insulin from your pancreas, blocks the liver from making more sugar, and slows down the movement of food through your stomach.

What are the side effects of Victoza?

The most common side effects of Victoza in clinical trials include:

  • Injection site reactions
  • Nausea
  • Gastrointestinal side effects – diarrhea, constipation, abdominal pain
  • Low blood sugar (hypoglycemia)
  • Headaches
  • Anxiety
  • Tremors

More serious side effects of Victoza include

  • Inflammation of the pancreas (pancreatitis)
  • Kidney and gallbladder problems
  • Increased risk of thyroid tumors and thyroid cancer

Contact your healthcare provider for medical advice about any adverse effects you experience while taking Victoza. You can report your side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Victoza contraindications

You should not use Victoza if you:

  • Are allergic to the active ingredient liraglutide
  • Have had an allergic reaction to any of the other ingredients found in Victoza
  • Have type 1 diabetes or diabetic ketoacidosis

Talk to your doctor before using Victoza if you:

  • Have severe heart disease
  • Have severe liver disease
  • Have kidney failure, are on dialysis, or have any other kidney problems
  • Have a severe stomach or gut problem
  • Have inflammatory bowel disease
  • Symptoms of acute pancreatitis (like a persistent, severe stomach ache)
  • Have thyroid disease
  • Are pregnant, or are planning to become pregnant
  • Are breastfeeding, or are planning to breastfeed

Is there a cheaper version of Victoza?

Currently, there isn’t a cheaper branded version of Victoza, and Victoza is not available as a generic (generics are cheaper non-branded versions of branded medications). Alternative prescription drugs for Victoza, such as metformin, or glipizide, sulfonylureas such as glimepiride, or branded medication such as Jardiance, Invokana, or Byetta (exenatide) may be available cheaper than Victoza. How much these alternatives will cost will depend on how much you buy and the retailer you buy them from.

Another cheaper way to help manage diabetes is to change your lifestyle. Healthy eating and regular exercise help with weight loss and managing your diabetes, especially if you are overweight. Speak to your doctor for further information and medical advice.

Is Ozempic the same as Victoza?

Both are GLP-1 receptor agonist medications used to treat type 2 diabetes. They are given as an injection under the skin (subcutaneous injection) using a self-injecting pen device, and they work in the same way. Although Ozempic and Victoza are similar, there are key differences between them.

Ozempic contains a GLP-1 receptor agonist called semaglutide, whilst Victoza contains a GLP-1 receptor agonist called liraglutide. Semaglutide and liraglutide do work in similar ways, but they are not identical, and you may respond to them differently.

Ozempic can be used in adults 18 years of age and older, and Victoza can be used in adults and children 10 years of age and older.

The doses prescribed for each drug also vary. Ozempic pens can be prescribed in 0.25 mg, 0.5 mg, and 1 mg doses, whereas Victoza pens can be prescribed in pre-filled, multi-dose pens that deliver 0.6 mg, 1.2 mg, or 1.8 mg doses.

The frequency of Ozempic and Victoza dosing also differs. Ozempic is a weekly semaglutide injection, and Victoza is a daily liraglutide injection.

Are Trulicity and Victoza the same thing?

Victoza contains liraglutide, and Trulicity contains dulaglutide as the active ingredient, both of which are classed as incretin mimetics. Victoza and Trulicity are both given as injections under the skin to treat Type 2 diabetes mellitus in adults, along with diet and exercise.

Victoza can be used in patients as young as 10 years old and is also indicated to reduce heart attacks and stroke in adults with type 2 diabetes and heart disease. Victoza is given once a day, while Trulicity is given once a week. Both of these medications have very similar side effects and drug interactions.

Victoza and Trulicity have been directly compared in a clinical study with adult patients that have Type 2 diabetes. The patients in this study also took metformin along with Victoza or Trulicity for 26 weeks. It showed that both medications were equally effective in improving patients’ blood glucose levels.

RELATED: Victoza vs Trulicity

Which is better, Victoza or Saxenda?

Victoza and Saxenda are both injectable medications that contain liraglutide. There are differences in the conditions approved by the U.S. Food and Drug Administration (FDA) to treat and the doses used.

Victoza is indicated along with diet and exercise to treat type 2 diabetes in adults and children 10 years of age and older. It is approved to reduce the potential risk of heart attack and stroke in adults with type 2 diabetes and cardiovascular disease.

Saxenda is used with diet and exercise for long-term body weight management in adults with a body mass index (BMI) of more than 30 kg/m2 or a BMI higher than 27 kg/m2 in patients who also have high blood pressure and high cholesterol.

RELATED: Saxenda vs Victoza

Is Victoza gluten-free?

Victoza is classed as gluten-free. However, there have been reports of glucose intolerance to Victoza. Cases of glucose intolerance have been reported in patients over the age of 60. It is important to understand that there have only been 1 or 2 cases of glucose intolerance reported each year since 2013.

Is Victoza a generic drug?

Victoza is not a generic diabetes drug. It is the brand name for a drug containing liraglutide as the active ingredient. Currently, there is no generic alternative available for Victoza on the market.

How do I use Victoza?

You can use Victoza once a day at any time of the day, with or without food. Inject Victoza under the skin (subcutaneous) in your stomach, thigh, or upper arm. Rotate the injection site with each injection of Victoza to reduce your risk of cutaneous amyloidosis (lumps under your skin).

If you forget to take a dose of Victoza, skip it and take your next dose at the usual time. Do not take extra doses of Victoza. Call your doctor immediately for medical attention if you think you have taken too much Victoza.

Victoza can interact with other medications. This can change how Victoza and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including over-the-counter, vitamins, and dietary supplements.

What is the best substitute for Victoza?

There are many alternatives to Victoza for the treatment of Type 2 diabetes. These include medicines such as metformin, glipizide, Trulicity, Ozempic, Tradjenta, Invokana, Levemir, and many others. Which treatment is best for you will depend on you and the condition you are being treated for. Speak to your doctor about the alternative treatments available.

Can I get my Victoza for free?

Victoza is covered by most health plans, including Medicare and Medicaid. Check with your plan for more details.

How much does Victoza cost?

Victoza prices without insurance will vary depending on where you buy it, the number of injectable pens per pack, and the strength of the pens. For a pack of three injectable pens with 3ml doses, you can pay around $530.

Breztri side effects and how to avoid them

Breztri Aerosphere is an FDA-approved medication manufactured by AstraZeneca. It is used to treat COPD symptoms. While Breztri Aerosphere is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Breztri Aerosphere include upper respiratory tract infections. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Breztri Aerosphere and what you can do to avoid them.

What is Breztri Aerosphere?

Breztri Aerosphere is a combination of budesonide, an inhaled corticosteroid (ICS), glycopyrrolate, a long-acting anticholinergic (sometimes called a long-acting muscarinic antagonist (LAMA)), and formoterol fumarate, a long-acting beta2-agonist ((LABA) bronchodilator).

What is the Breztri Aerosphere used for?

Breztri Aerosphere is used for the maintenance treatment of COPD (chronic obstructive pulmonary disease). COPD is a chronic lung disease that includes chronic bronchitis, emphysema, or both. Breztri aerosphere will reduce the annual rate of moderate or severe COPD exacerbations.

Breztri Aerosphere is not for the treatment of asthma, sudden breathing problems, or acute bronchospasm. It is not a rescue inhaler. LABA medicines increase the risk of hospitalizations and death when used alone. Breztri Aerosphere contains an ICS, an anticholinergic, and a LABA. When an ICS and LABA are used together, there is not a significant risk of hospitalizations and deaths from asthma problems. Breztri Aerosphere can improve lung function and reduce the number of COPD flare-ups you have.

How does Breztri Aerosphere work?

Budesonide reduces irritation and swelling of airways in your lungs. Glycopyrrolate and formoterol help to relax muscles around airways in the lungs, opening them up and allowing you to breathe easier.

What are the side effects of Breztri Aerosphere?

The most common side effects of Breztri aerosphere in clinical trials include:

  • Upper respiratory tract infection, pneumonia
  • Back pain, muscle spasm
  • Oral thrush, cough, sinusitis
  • Flu-like symptoms, body aches
  • Unusual tiredness
  • Urinary tract infection
  • Diarrhea

More serious side effects of Breztri aerosphere include:

  • Potential worsening of infections such as existing tuberculosis, fungal, bacterial, viral, or parasitic infections, ocular herpes simplex
  • Risk of impaired adrenal function
  • Hypercorticism and adrenal suppression
  • Paradoxical bronchospasm
  • Glaucoma and cataracts, worsening of narrow-angle glaucoma, eye pain
  • Changes in vision such as seeing halos around lights, and blurred vision
  • Worsening of urinary retention
  • Hypokalemia – low levels of potassium may cause symptoms of muscle spasm, muscle weakness, or abnormal heart rhythm
  • Hyperglycemia (high blood sugar levels)
  • Effects on your heart – increased blood pressure, fast heart rate (palpitations), irregular heartbeat, or chest pain
  • Serious allergic reactions – rash, hives, swelling of your face, mouth, and tongue, breathing problems, and shortness of breath

You are encouraged to report possible side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Breztri Aerosphere dosage

Breztri aerosphere is available as an oral inhalation aerosol, in the following doses: Pressurized metered-dose inhaler containing a combination of budesonide (160 mcg), glycopyrrolate (9 mcg), and formoterol fumarate (4.8 mcg) per inhalation.

Please read the full prescribing information and patient information for patient safety information, and always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Breztri Aerosphere drug interactions

Breztri Aerosphere can interact with other medications including:

  • Strong cytochrome P450 3A4 inhibitors – ketoconazole, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole
  • Other adrenergic drugs
  • Diuretics
  • Xanthine derivatives or steroids
  • Monoamine oxidase inhibitors and tricyclic antidepressants
  • Beta-blockers
  • Anticholinergics such as ipratropium, or tiotropium
  • LABA drugs such as arformoterol, or salmeterol

Before taking Breztri Aerosphere, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Breztri Aerosphere warnings & precautions

You should not use Breztri aerosphere if you:

  • Are allergic to the active ingredient budesonide, glycopyrrolate, or formoterol fumarate
  • Have had an allergic reaction to any of the other ingredients in Breztri aerosphere

Talk to your doctor before using Breztri aerosphere if you:

  • Are taking any of the medications that could interact with Breztri aerosphere
  • Have hepatic impairment
  • Have renal impairment
  • Have heart problems or high blood pressure
  • Suffer from seizures
  • Have thyroid problems
  • Have diabetes
  • Have osteoporosis
  • Have problems with your immune system
  • Have eye problems such as glaucoma or cataracts
  • Have prostate or bladder problems, or problems passing urine
  • Have a viral, bacterial, parasitic, or fungal infection such as chicken pox or measles
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Breztri Aerosphere, to make sure it is safe for you.

Does Breztri Aerosphere cause weight gain?

Weight gain is not a side effect of using the Breztri Aerosphere. If you experience weight gain or weight loss during treatment with Breztri speak to your healthcare provider for medical advice.

Can you stop taking Breztri Aerosphere?

If you are considering stopping treatment with Breztri Aerosphere speak to your doctor first. Certain conditions such as asthma or allergies may flare up if you suddenly stop using Breztri Aerosphere.

If you have sudden worsening of breathing problems, or a serious allergic reaction to Breztri Aerosphere, stop using it immediately and call your healthcare provider for emergency medical advice.

Who should not take Breztri Aerosphere?

Do not use Breztri Aerosphere if you are allergic to any of the active ingredients (budesonide, glycopyrrolate, or formoterol fumarate), or if you have had an allergic reaction to any of the other ingredients in Breztri aerosphere in the past. Also, this medication is not FDA-approved to be used by patients younger than 18 years of age.

Does Breztri Aerosphere have a steroid?

Breztri Aerosphere contains budesonide, glycopyrrolate, and formoterol. Budesonide is classed as a corticosteroids, and reduces swelling and irritation of airways in your lungs.

How good is Breztri Aerosphere for COPD?

Long-term use of Breztri Aerosphere helps to prevent COPD flare-ups by more than 50%.

What does Breztri Aerosphere do to your body?

Breztri Aerosphere reduces irritation and swelling of airways in your lungs, and helps to relax muscles around airways in the lungs, opening them up and allowing you to breathe easier.

How to avoid Breztri Aerosphere side effects

The best way to avoid side effects is to take Breztri Aerosphere as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Breztri Aerosphere that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Breztri Aerosphere. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

You are advised to consume alcohol cautiously. Alcohol may interact with glycopyrrolate and cause increased drowsiness and dizziness. Speak to your healthcare provider about safe levels of alcohol consumption when using Breztri Aerosphere.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Breztri Aerosphere.

7. Know the signs and symptoms of Breztri Aerosphere side effects

Signs and symptoms of side effects of Breztri Aerosphere include oral thrush and upper respiratory tract infections. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Weight gain is not a side effect of using the Breztri Aerosphere. If you experience weight gain or weight loss during treatment with Breztri speak to your healthcare provider.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Breztri Aerosphere.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Breztri Aerosphere as needed.

Novolog side effects and how to avoid them

Novolog is an FDA-approved brand-name medication manufactured by Novo Nordisk. It is classified as a fast acting insulin analog and is used to improve the control of blood sugar levels in adults and children with Type 1 diabetes and Type 2 diabetes mellitus. While Novolog is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Novolog include injection site reactions. Less common, but more serious side effects, can include hypoglycemia.

Learn more about the side effects of Novolog and what you can do to avoid them.

What is Novolog (insulin aspart)?

NovoLog is a man-made insulin used to control high blood sugar levels (hyperglycemia) in people with diabetes. It can be prescribed to adults and children over two years old. NovoLog is a fast-acting type of insulin. It works in the same way as insulin produced by the pancreas in your body, by helping your cells to absorb sugar from your blood.

The active ingredient in NovoLog is called insulin aspart. When you inject NovoLog, insulin aspart can start lowering your blood sugar levels within 10 to 20 minutes. This can help to lower your blood sugar levels after you’ve eaten and allow you to maintain normal blood sugar levels.

Always check with your doctor or pharmacist before taking any medication, including Novolog, to make sure it is safe for you.

Novolog dosage

Novolog is available in the following dose: 100 units/mL (U-100), in the following formulations:

  • 10 mL vials
  • 3 mL PenFill cartridges for use in the 3 mL PenFill cartridge device
  • NovoLog FlexPen (insulin pen)
  • 3 mL NovoLog FlexTouch

Inject your insulin dose under your skin (subcutaneous injection) in your thighs, buttocks, or upper arms when you eat, usually twice a day. This can help lower your blood sugar to normal levels and can reduce the symptoms and complications of your diabetes.

Your healthcare provider may prescribe a glucagon kit just in case you develop severe hypoglycemia. Be aware that increased thirst or urination are signs of high blood sugar.

Store Novolog away from heat and light. Do not freeze and throw away insulin that has been frozen. Refrigerate Novolog and use until the expiration date or keep at room temperature and use it within 28 days.

You are advised to read the prescribing information and medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How soon should you eat after taking NovoLog?

You should eat a meal within 5 to 10 minutes after using NovoLog, to avoid low blood sugar. You should not use NovoLog if you are not going to eat right after you have injected Novolog.

What should you do if you forget to eat after taking NovoLog?

If you forget to eat after using Novolog you may become hypoglycemic, because your blood glucose level gets too low. When this happens you may feel tired, weak, confused, and irritable. To treat hypoglycemia quickly, eat or drink a source of sugar such as fruit juice, glucose tablets, raisins, or soda.

What are the common side effects of Novolog

The most common side effects of Novolog in clinical trials include:

  • Reactions at the injection site, like itching, rashes, skin thickening, or pits forming in your skin (lipodystrophy)
  • Localized cutaneous amyloidosis (skin with lumps) with repeated insulin injections
  • Weight gain
  • Swelling (edema) of your hands and feet
  • Low levels of potassium in your blood (hypokalemia)

More serious side effects of Novolog include

  • Severe life-threatening hypersensitivity reactions including anaphylaxis – swelling of the face or throat, shortness of breath, trouble breathing, or itchy skin rash
  • Severe hypoglycemia (low blood sugar) – increase how often blood glucose is monitored when there are changes to insulin dosage, other glucose-lowering drugs, changes in meal pattern, or physical activity in those with renal or hepatic impairment, and in patients with hypoglycemia unawareness. According to the American Diabetes Association symptoms of low blood sugar levels include anxiety, behavior similar to being drunk, blurred vision, cold sweats, confusion, depression, lightheadedness, drowsiness, hunger, fast heartbeat, headache, irritability, restless sleep, and tingling in the hands, feet, lips, or tongue
  • Hypokalemia (low potassium levels)
  • Fluid retention and heart failure when used with thiazolidinediones

These aren’t all the side effects Novolog can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to your physician or pharmacist.

What are the long-term side effects of Novolog?

Long-term use of Novolog may cause lipodystrophy at the injection site. Lipodystrophy includes the thickening or thinning of adipose tissue and can affect the absorption of insulin.

Novolog drug interactions

Novolog can interact with other medications. These include:

  • Monoamine oxidase inhibitors (MAOI), taken to treat depression
  • Beta-blockers, taken to treat high blood pressure
  • Angiotensin-converting enzyme (ACE) inhibitors, taken to treat high blood pressure and certain heart conditions
  • Contraceptive/birth control pills
  • Thiazide diuretics, taken to treat high blood pressure or excessive fluid retention
  • Glucocorticoids, such as cortisone, taken to treat inflammation
  • Thyroid hormones, taken to treat thyroid gland disorders
  • If you have heart failure, taking thiazolidinediones such as rosiglitazone and pioglitazone may make heart failure worse
  • Alcohol, or any medications that contain alcohol

Novolog can interact with other medications. This can change how Novolog and other medications work and can make side effects more likely. Tell your prescribing physician about all your prescription drugs, including vitamins and dietary supplements.

Novolog warnings & precautions

You should not use Novolog if you:

  • Are allergic to the active ingredient insulin aspart, or any other forms of insulin
  • Have had an allergic reaction to any of the other ingredients in NovoLog

Talk to your doctor before using Novolog if you:

  • Are taking any of the medications that could interact with NovoLog
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Novolog, to make sure it is safe for you.

Can you use Novolog when breastfeeding?

NovoLog use during breastfeeding is safe but dose adjustments may be needed in breastfeeding mothers. NovoLog is FDA-approved to be used in children for subcutaneous infusion by an insulin pump, and subcutaneous injection.

Does NovoLog make you lose weight?

No, NovoLog causes weight gain and fluid retention. Speak to your doctor if you are concerned about weight gain or any other side effects of insulin.

What is the treatment for low blood sugar (hypoglycemia)?

To treat symptoms of hypoglycemia quickly, eat or drink a source of fast-acting carbs such as fruit juice, glucose tablets or gel, raisins, honey, or regular soda.

What is the most common symptom of low blood sugar?

The most common symptoms of low blood sugar (hypoglycemia) are hunger, dizziness, shaking, feeling anxious, confusion and irritability.

What happens if I take too much NovoLog?

Taking an overdose of Novolog may cause hypoglycemia (low blood sugar) or hypokalemia (low potassium levels). Low blood sugar levels can be life-threatening.

How many units of NovoLog are in a pen?

Each Novolog pen contains 300 units of insulin aspart in a 3 ml solution for injection.

How to avoid Novolog side effects

The best way to avoid side effects is to take Novolog as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Novolog that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Novolog. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Novolog as it can increase your risk of hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Novolog.

7. Know the signs and symptoms of Novolog side effects

Signs and symptoms of side effects include injection site reactions. If you experience any of these symptoms speak to your healthcare provider for medical advice.

8. Monitor your weight

Novolog may cause weight gain. If you experience this side effect while taking Humalog, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Novolog.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Novolog as needed.

Breo Ellipta side effects and how to avoid them

Breo Ellipta is an FDA-approved brand-name medication manufactured by GSK. Breo Ellipta contains two active ingredients, fluticasone furoate, a steroid, and vilanterol, a long-acting bronchodilator (LABA), and is used for the treatment of COPD (chronic obstructive pulmonary disease) and for the treatment of asthma. While Breo Ellipta is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Breo Ellipta include oral thrush and bronchitis. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Breo Ellipta and what you can do to avoid them.

Why do people take Breo Ellipta (fluticasone/vilanterol)?

Breo Ellipta is used daily to open up your airways and make breathing easier, providing relief from the symptoms of COPD and asthma. It also helps to reduce the chances and severity of the sudden onset of severe symptoms, like asthma attacks.

Breo Ellipta is not recommended for use in people with acute bronchospasm or asthma that can be managed with ICS (inhaled corticosteroids) or inhaled short-acting beta2-agonist prescription drugs such as ProAir HFA, Proventil HFA, or Ventolin HFA that contain albuterol.

Breo Ellipta contains two active ingredients, fluticasone furoate, a steroid, and vilanterol, a long-acting bronchodilator (LABA). They work together to relieve COPD and reduce your chances of having an asthma attack. When taken regularly, Breo Ellipta can ease COPD and asthma symptoms, and reduce the number and severity of asthma attacks

What are the common side effects of Breo Ellipta?

The most common side effects of Breo Ellipta in clinical trials include:

  • Upper respiratory tract infections
  • Bronchitis
  • Influenza
  • Fever, headaches
  • Sinusitis, runny nose
  • A sore throat, throat pain, cough
  • Oral thrush (candidiasis) infections
  • Back pain, joint pain
  • Tiredness or muscle weakness
  • Increased risk for high blood pressure, altered heart rate, or irregular heartbeat

More serious side effects of Breo Ellipta include:

  • Severe life-threatening allergic reactions – hives, trouble breathing, swelling of your face, lips, tongue, and throat
  • Hypokalemia (low potassium level)
  • Osteoporosis
  • Pneumonia – fever, shortness of breath, cough or chest pain
  • High blood sugar – symptoms include frequent urination, increased thirst, overeating, poor wound healing, weight loss, infections
  • Sudden worsening of breathing problems (paradoxical bronchospasm)

These aren’t all the side effects Breo Ellipta can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to a healthcare professional.

Breo Ellipta dosage

Breo Ellipta is available as a Breo comes as a dry powder inhaler. The inhaler contains 2 foil blister strips of the powder formulation that is used for oral inhalation. One of the strips contains fluticasone furoate 100 or 200 mcg per blister and the other strip contains vilanterol 25 mcg per blister.

For the maintenance treatment of COPD use 1 inhalation of Breo Ellipta 100/25 once daily. For asthma use, 1 inhalation of Breo Ellipta 100/25 or 200/25 once daily. Breo Ellipta is a once-daily medication used to treat various respiratory issues, such as chronic bronchitis and emphysema. Breo is not a rescue inhaler and should not be used in cases of a sudden breathing problem. If you forget to take a dose, skip the missed dose and take your next dose at the usual time. Do not double your doses.

Is it safe to take Breo Ellipta and other medications?

Breo Ellipta can interact with other medications. These include:

  • Other medicines that contain a LABA (beta2-adrenergic agonist) – formoterol, salmeterol
  • Beta-blockers
  • Diuretics
  • Certain antifungals such as itraconazol, ketoconazole, and voriconazole
  • Monoamine oxidase inhibitors
  • Tricyclic antidepressants
  • CYP3A4 inhibitors such as clarithromycin, ritonavir, and grapefruit

Breo Ellipta can cause drug interactions with other medications. This can change how Breo Ellipta and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Breo Ellipta warnings & precautions

You should not use Breo Ellipta if you:

  • Are allergic to the active ingredients fluticasone furoate or vilanterol
  • Are allergic to any of the other ingredients in Breo Ellipta
  • Have a severe allergy to milk proteins
  • Are under 18 years of age

Talk to your doctor before starting to use Breo Ellipta if you:

  • Have any heart problems
  • Have any immune system problems
  • Have high blood pressure
  • Have a current viral, bacterial, fungal, or parasitic infection
  • Have been exposed to measles or chickenpox
  • Suffer from seizures
  • Have any thyroid problems
  • Have diabetes or high blood sugar
  • Have any liver problems
  • Have osteoporosis
  • Have any eye problems, like glaucoma, cataracts, or an increase in pressure in your eyes
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed – there is no knowledge of fluticasone furoate/vilanterol passes into breast milk

Please read the prescribing information and drug information provided with your medication and always speak with your healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Does Breo Ellipta cause weight gain?

Breo Ellipta may cause weight gain due to high cortisol levels caused by Breo Ellipta. If you are concerned about weight gain with Breo Ellipta talk to your doctor.

Does Breo Ellipta cause withdrawal symptoms?

Stopping treatment with Breo Ellipta may cause your symptoms to become worse. Speak to your healthcare professional first if you are considering stopping treatment with Breo Ellipta.

How long can you stay on Breo Ellipta?

You should continue to use Breo Ellipta unless your healthcare professional tells you otherwise. Breo Ellipta will continue to work as long as you continue to use it. Your doctor will choose an alternative medicine for you if needed.

Does Breo have a steroid in it?

Breo Ellipta contains fluticasone and vilanterol. Fluticasone is a steroid and vilanterol is a bronchodilator.

What does Breo Ellipta do to your lungs?

Breo Ellipta reduces swelling in your lungs helping you to breathe more easily. Vilanterol helps to relax muscles around your airways helping to open them up and allowing you to breathe easier.

Does Breo cause a decrease in bone mineral density?

Using steroid inhalers does increase the risk of osteoporosis and increases the risk of broken bones.

What is the difference between the side effects of Breo Ellipta and the side effects of other inhalers?

The side effects experienced when using an inhaler will vary depending on the active ingredients of the inhaler you are using. Speak to your healthcare professional to discuss your options, and to learn more about the potential side effects before you start using any inhalers.

How to avoid Breo Ellipta side effects

The best way to avoid side effects is to take Breo Ellipta as directed by your doctor. Follow your doctor’s instructions carefully and do not use more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Breo Ellipta that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Breo Ellipta. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol does not directly affect using a Breo Ellipta. However, alcohol may worsen the symptoms of asthma or COPD. Speak to your healthcare provider for medical advice around alcohol consumption when using Breo Ellipta.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Breo Ellipta.

7. Know the signs and symptoms of Breo Ellipta side effects

Signs and symptoms of side effects include oral thrush and upper respiratory tract infections. If you experience any of these symptoms speak to your doctor.

8. Monitor your weight

Breo Ellipta may cause weight loss or weight gain, depending on whether Breo Ellipta increases or decreases your cortisol levels (Breo Ellipta can do both). If you experience changes in your weight while taking Breo Ellipta, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Breo Ellipta.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Breo Ellipta as needed.

Humalog side effects and how to avoid them

Humalog is an FDA-approved brand-name diabetes medication manufactured by Eli Lilly. It is classified as a type of insulin used to treat diabetes. While Humalog is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Humalog include injection site reactions. Less common, but more serious side effects, can include hypoglycemia.

Learn more about the side effects of Humalog and what you can do to avoid them.

What is Humalog (insulin lispro)?

Humalog is a fast-acting insulin used to treat type 1 diabetes and type 2 diabetes mellitus. You inject Humalog under your skin or use it with an insulin pump just after you’ve eaten, to lower your blood sugar.

The active ingredient in Humalog is called insulin lispro, a rapid-acting insulin. It’s similar to normal human insulin, and works in the same way, but has been modified to be faster acting. When you inject or pump Humalog into your body, it enters your blood supply. It then increases the rate at which your liver, and your fat and muscle cells, absorb sugar from your blood.

Check with your doctor or pharmacist before taking any medication, including Humalog, to make sure it is safe for you.

What are the common side effects of Humalog?

The most common possible side effects of Humalog include:

  • Injection site reactions
  • Lipodystrophy
  • Weight gain
  • Edema
  • Pruritus
  • Rash

Humalog can cause more serious side effects, including:

  • Hypoglycemia (low blood sugar) – increase how often blood glucose is monitored when there are changes to insulin dosage, other glucose-lowering drugs, changes in meal pattern, or physical activity in those with renal or hepatic impairment, and in patients with hypoglycemia unawareness. According to the American Diabetes Association symptoms of low blood sugar levels include anxiety, behavior similar to being drunk, blurred vision, cold sweats, confusion, depression, lightheadedness, drowsiness, hunger, fast heartbeat, headache, irritability, restless sleep, and tingling in the hands, feet, lips, or tongue
  • Severe life-threatening allergic reactions – swelling of the face or throat, shortness of breath, trouble breathing, or itchy skin rash
  • Hypokalemia (low potassium levels)
  • Fluid retention and heart failure when used with thiazolidinediones

If you experience any of these serious side effects, stop taking Humalog and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Humalog?

Long-term use of Humalog may cause lipodystrophy at the injection site with repeated use. Lipodystrophy includes the thickening or thinning of adipose tissue and can affect the absorption of insulin.

Humalog dosage

Humalog is available as 10 mL vials, 3 mL prefilled pens, 3 mL Humalog KwikPen prefilled Pens, or 3 mL cartridges.

Humalog may be administered as a subcutaneous injection in your thighs, buttocks, or upper arms, as a continuous subcutaneous infusion, or intravenously. Your dose will be based on your condition and the method of administration.

You may experience hypoglycemia when using Humalog and feel hungry, irritable, dizzy, confused, or shaky. To treat hypoglycemia quickly, eat or drink a source of sugar such as fruit juice, glucose tablets, raisins, or soda. Your healthcare provider may prescribe a glucagon kit just in case you develop severe hypoglycemia. Be aware that increased thirst or urination are signs of high blood sugar.

Store Humalog away from heat and light. Do not freeze and throw away insulin that has been frozen. Refrigerate Humalog and use until the expiration date or keep at room temperature and use it within 28 days.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Humalog drug interactions

Humalog can interact with other medications including:

  • Antidiabetic agents
  • ACE inhibitors
  • Angiotensin II receptor-blocking agents
  • Monoamine oxidase inhibitors
  • Atypical antipsychotics
  • Corticosteroids
  • Estrogens
  • Beta-blockers
  • If you have heart failure, taking thiazolidinediones such as rosiglitazone and pioglitazone may make heart failure worse

Before taking Humalog, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Does Humalog cause hair loss?

Hair loss is a side effect of using Humalog, especially in 60+ females, who have been taking Humalog for 2 to 5 years.

Does Humalog cause heart problems?

Humalog can cause heart-related problems such as changes in your heart rhythm. Your heart may feel as though it is racing, fluttering, or skipping beats.

Humalog warnings & precautions

Don’t take Humalog if you:

  • Are allergic to the active ingredient insulin lispro
  • Are allergic to any of the other ingredients found in Humalog (listed in the leaflet which comes with the medication)
  • Think hypoglycemia is starting (a fall in blood sugar to low levels)

Talk to your doctor before using Humalog if you:

  • Often have hypoglycemia or have problems recognizing it’s happening
  • Have problems with your kidneys or liver
  • Have recently become ill
  • Are exercising more than usual
  • Are planning to travel or go on vacation (time differences can change when you eat and when you take your Humalog)
  • Have heart failure or other heart problems
  • Are breastfeeding or plan to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Humalog, to make sure it is safe for you.

How long does Humalog stay in your system?

Humalog begins to work within 15 minutes, reaches a peak around 1 to 2 hours after injection, and works for about 2 to 4 hours.

Is diarrhea a side effect of Humalog?

Yes. Humalog may cause diarrhea in some patients. Speak to your doctor if you often have diarrhea when using Humalog.

What are the side effects of not having enough insulin?

Not having enough insulin will cause your body to break down its stores of fat and muscle, leading to weight loss and diabetic ketoacidosis, a condition where the bloodstream becomes acidic, ketones build up and you become dehydrated.

What other insulin is there?

Other types of insulin include short-acting insulin, intermediate-acting insulin, mixed insulin, and long-acting insulin. Which insulin works best for you will depend on you as an individual and will be dependent on factors such as your age, weight, and your symptoms of diabetes. Speak to your doctor for further advice.

How to avoid Humalog side effects

The best way to avoid side effects is to take Humalog as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Humalog that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Humalog. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Humalog as it can increase your risk of hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Humalog.

7. Know the signs and symptoms of Humalog side effects

Signs and symptoms of side effects include feeling tired, and shortness of breath. If you experience any of these symptoms speak to your healthcare provider for medical advice.

8. Monitor your weight

Humalog may cause weight gain. If you experience this side effect while taking Humalog, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Humalog.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Humalog as needed.

Rituxan side effects and how to avoid them

Rituxan is a brand-name medication manufactured by Genentech. It is classified as a monoclonal antibody and is used to treat cancer. While Rituxan is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Rituxan include tiredness and muscle aches. Less common, but more serious side effects, can include kidney and heart problems.

Learn more about the side effects of Rituxan and what you can do to avoid them.

What is Rituxan (rituximab)?

Rituxan is a prescription medication used to treat some types of cancer and autoimmune diseases, including:

  • Non-Hodgkin’s lymphoma (NHL), in adults
  • Chronic lymphocytic leukemia (CLL), in adults
  • Rheumatoid arthritis, in adults
  • Granulomatosis with polyangiitis (GPA), in adults and children aged 2 and older
  • Microscopic Polyangiitis (MPA), in adults and children aged 2 and older
  • Moderate to severe pemphigus vulgaris in adults

If you have cancer that affects your white blood cells or have one of the inflammatory autoimmune diseases above, your doctor may have prescribed Rituxan to you. It is a medication that can reduce the buildup of cancerous and non-cancerous lymphocytes and reduces the amount of inflammation your lymphocyte cells can cause.

Rituxan side effects

The most common possible side effects of Rituxan include:

  • Tiredness
  • Body aches
  • Sore throat
  • Fever
  • Chills
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Muscle spasms
  • Temporary low blood pressure
  • A fall in red blood cell counts (anemia)
  • A fall in white blood cell counts
  • An increased risk of infections
  • Increased thirst or urination

Rituxan can cause more serious side effects, including:

  • Progressive multifocal leukoencephalopathy (PML) – a rare but serious brain infection that can cause severe disability and death in serious cases
  • Tumor lysis syndrome – a condition caused by the fast breakdown of tumor cells that can result in kidney damage and failure, and heart rhythm problems
  • Heart problems, including chest pain, irregular heartbeats, and heart attacks that can cause lasting damage and can be fatal
  • Kidney problems that can reduce kidney function and that can cause fatal kidney failure in severe cases
  • Severe allergic reactions to the medication that can cause dizziness, a rapid heartbeat, rashes, itching, and hives, as well as swelling in your face, mouth, and throat that can cause breathing difficulties and shortness of breath
  • Stomach and bowel problems that can be fatal in serious cases
  • Severe skin reactions including inside your mouth, that can result in peeling, blistering, sores, and ulcers
  • Reactivation of the hepatitis B virus if you have previously had a hepatitis B infection
  • Increased risk of contracting a serious infections
  • Upper respiratory tract infections

If you experience any of these serious side effects, stop taking Rituxan and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Rituxan?

Long-term side effects of Rituxan may include heart problems, serious kidney problems, serious infections, such as shingles, and reactivation of the hepatitis B virus.

How long do Rituxan side effects last?

Side effects from using Rituxan can occur at any time during and after Rituxan treatment, when the drug is in your system. Side effects could continue for up to 3 years in some cases, depending on the condition you are being treated for.

Rituxan dosage

Rituxan is available as a solution for infusion in the following doses. 100 mg/10 mL and 500 mg/50 mL in single-dose vials.

Rituxan is given to you as an infusion directly into a vein as an intravenous infusion by a doctor or other healthcare professional. Your first infusion will be administered slowly and you will be observed closely while you receive it. Your doctor will prescribe Rituxan to you based on how often you will need infusions and your medical history.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Rituxan drug interactions

Rituxan can interact with other medications including:

Before taking Rituxan, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Rituxan warnings & precautions

Don’t take Rituxan if:

  • Are allergic to the active ingredient rituximab
  • Are allergic to any of the other ingredients in Rituxan
  • Are pregnant or are planning to become pregnant – speak to your doctor about using birth control

Rituxan should not be given to children for conditions other than granulomatosis with polyangiitis (GPA) or microscopic Polyangiitis (MPA). It should also not be given to children under the age of 2 for GPA or MPA.

Talk to your doctor before taking Rituxan if you:

  • Are taking any of the medications that could interact with Rituxan
  • Have or have ever had any heart problems
  • Have any kidney problems
  • Have any lung problems
  • Have a weakened immune system
  • Currently have an infection
  • Have or have ever had a serious infection. This includes cytomegalovirus, parvovirus B19, herpes, chickenpox or shingles, or hepatitis A, B, or C
  • Have lung disease
  • Have recently had a vaccination or are due to have one
  • Are breastfeeding or are planning to breastfeed – It is not known if Rituxan passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Rituxan, to make sure it is safe for you.

Does Rituxan cause weight gain?

Weight gain may occur with Rituxan, but only in those who took it for Non-Hodgkin’s lymphoma.

What side effects occur with Rituxan during infusion?

Rituxan may cause life-threatening infusion-related reactions and need medical attention right away. Speak to your doctor immediately if you develop symptoms such as fever, shaking, itching, rash, trouble breathing, dizziness, feeling lightheaded, or fainting.

How long does it take to recover using Rituxan?

Rituximab reduces the number of B-cells in your body, helping to reduce inflammation, pain, and joint damage. Your symptoms will improve after around 8 to 16 weeks after you began treatment with Rituxan.

What does Rituxan do to your body?

The active ingredient in Rituxan is called rituximab. It is a type of antibody protein specifically designed to target white blood cells called lymphocytes. Lymphocyte white blood cells are involved in some cancers and are used by your immune system to trigger inflammation. Rituximab attaches to the surface of lymphocyte white blood cells and destroys them.

For cancers like non-Hodgkin’s lymphoma, rituximab can reduce the number of cancerous lymphocytes you have. For chronic lymphocytic leukemia, rituximab can prevent the harmful buildup of lymphocytes. In the case of autoimmune diseases, rituximab can cause a fall in your lymphocyte levels. This reduces the amount of inflammation your lymphocyte white blood cells can trigger.

How does Rituxan make you feel?

The most common side effects of Rituaxn includes fever, muscle aches, headaches, tiredness and chills. These are all signs of infection.

What is the difference between Rituxan and other chemo drugs?

Chemotherapy is a treatment using drugs to kill cancer cells that grow rapidly in your body. Chemotherapy can unfortunately harm healthy cells in your body, causing side effects, such as tiredness. Rituxan is not chemotherapy. Rituxan works by finding and attacking cells where the cancer begins.

What is the procedure for getting Rituxan?

Rituxan is a prescription drug only available when prescribed by your doctor. Rituxan is injected directly into your bloodstream as an intravenous infusion by a healthcare professional.

How to avoid Rituxan side effects

The best way to avoid side effects is to take Rituxan as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Rituxan that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Rituxan. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is safe to consume while you are using Rituxan but you are recommended to keep to the recommended guidelines for men and women.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Rituxan.

7. Know the signs and symptoms of Rituxan side effects

Signs and symptoms of side effects include tiredness and muscle aches. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Rituxan may cause weight gain or weight loss. If you experience this side effect while taking Rituxan, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Rituxan.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Rituxan as needed.

Xolair side effects and how to avoid them

Xolair is a brand-name medication manufactured by Genentech, Inc. It is classified as an anti-immunoglobulin E (IgE) antibody and is used to treat asthma symptoms, nasal polyps, and chronic hives. While Xolair is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Xolair include injection site reactions and infections. Less common, but more serious side effects, can include blood clots.

Learn more about the side effects of Xolair and what you can do to avoid them.

What is Xolair (omalizumab)?

Xolair (omalizumab) is an injectable biologic medication. It was approved in 2003 by the U.S. Food and Drug Administration (FDA) to treat asthma symptoms, nasal polyps, and chronic hives. Your first dose of Xolair is typically given in a healthcare setting such as your doctor’s office due to the risk of severe allergic reactions.

Xolair is an anti-immunoglobulin E (IgE) antibody. IgE plays an essential role in your immune system’s response to allergens. Xolair binds to IgE receptors in mast cells, preventing them from releasing histamine and other chemicals that are associated with your body’s allergic response as well as inflammation. Xolair can reduce the IgE levels in your blood by more than 90%, which helps reduce the symptoms of asthma and other conditions.

More information on what is Xolair and Xolair dosage

What does Xolair do?

Xolair (omalizumab) is an anti-IgE antibody indicated to treat:

  • Moderate to severe persistent asthma in patients 6 years of age and older for whom other asthma medications such as inhaled corticosteroids have not worked
  • Nasal polyps in adults who did not respond to nasal corticosteroids
  • Chronic spontaneous urticaria (CSU), which used to be called chronic idiopathic urticaria (CIU), in patients 12 years of age and older who still have symptoms after taking antihistamines

Xolair should not be used to treat acute asthma attacks, bronchospasm, or other allergic conditions besides CSU.

What are the most common side effects of Xolair?

The most common side effects of Xolair include:

  • Joint pain
  • Injection site reactions
  • Leg pain
  • Dizziness, headaches, tiredness
  • Sinus infections, sore throat, common cold symptoms
  • Fever
  • Nausea
  • Earache
  • Rash
  • Upper abdominal pain
  • Upper respiratory tract infections
  • Nose bleeds

Xolair can cause more serious side effects, including:

  • Life-threatening allergic reactions (hives, chest tightness, low blood pressure, shortness of breath, and trouble breathing
  • Increased risk of heart attack, blood clots, and chest pain
  • Increased risk of cancer
  • Bone fractures
  • Inflammation of the blood vessels
  • High risk of parasitic infections

If you experience any of these serious side effects, stop taking Xolair and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are Xolair’s long-term side effects?

Long-term side effects of Xolair may include an increased risk of cancer, osteoporosis, inflammation of blood vessels, and increased risk of heart attack, blood clots, and chest pain.

How long do Xolair side effects last?

Some side effects of Xolair may occur shortly after Xolair injection or within five days. How long the side effect last will depend on the side effect. Speak to your healthcare provider about any side effects you experience, especially those that are persistent.

Xolair dosage

Xolair is available in injection form in the following doses: 75 mg/0.5 mL and 150 mg/mL in a single-dose prefilled syringe, or 150 mg lyophilized powder in a single-dose vial.

You are advised to read the prescribing information and medication guide provided with this medicine for the full drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Xolair drug interactions

When Xolair is taken with other medications, it may change the way they work or increase the frequency and severity of side effects. No formal drug interaction studies have been performed with Xolair. However, you should discuss with your doctor whether any of the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take may interact with this medication.

Xolair warnings & precautions

Don’t take Xolair if you:

  • Are allergic to the active ingredient omalizumab
  • Are allergic to any of the other ingredients in Xolair (you can find these listed in the leaflet which comes with the medication)
  • Are allergic to latex (the needle cap of the syringe may contain latex)
  • Are under six years of age for the treatment of allergic asthma
  • Are under 12 years of age for the treatment of hives (chronic spontaneous urticaria)
  • Are using it to treat allergic conditions other than allergic asthma or hives (chronic spontaneous urticaria)

Talk to your doctor before taking Xolair if you:

  • Have a kidney or liver condition
  • Have an autoimmune disease
  • Have ever had a severe allergic reaction (anaphylaxis) brought on by other medication or by non-medical causes, like an insect bite or by food
  • Are pregnant or trying to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if Xolair passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Xolair, to make sure it is safe for you.

How effective is Xolair?

Xolair’s effectiveness is dose-dependent. Those using Xolair 300 mg had around 66% reduction in the severity of their itching and hives. Those using Xolair 150 mg saw almost a 50% reduction in the same symptoms.

How dangerous is Xolair?

Xolair may cause serious side effects such as breast cancer, prostate cancer, bone fracture, and parasitic infection.

Does Xolair cause hair loss?

Xolair may cause hair loss in around 2% of patients. Hair loss will last for a short period of about 3 to 4 months.

Does Xolair cause hives?

Xolair treatment may cause an allergic reaction, including anaphylaxis, symptoms of which may include a skin rash.

Does Xolair weaken your immune system?

Xolair does not weaken the immune system and is not linked to an increased risk of infection.

How long can you stay on Xolair?

Xolair treatment is recommended for 4 weeks for conditions such as chronic hives but most patients can tolerate longer treatments and will use Xolair as a long-term treatment.

Can Xolair cause weight gain?

Xolair does not cause weight gain or weight loss. Speak to your doctor if you have changes in your weight while taking Xolair.

What cancers are associated with Xolair?

Cancers most commonly associated with Xolair treatment include breast, prostate, melanoma, non-melanoma skin, and parotid cancer.

Can Xolair be used in children?

Xolair may be used in children 6 years of age and older, already being treated with high-dose steroid and beta-agonist inhalers whose symptoms are not well controlled.

What is the cost of Xolair?

Xolair prices will vary depending on where you buy it from and if you purchase the pre-filled syringes or the powder for subcutaneous injection. As a guide, you can expect to pay over $1,000 for a 150 mg pack of powder for injection.

Can Xolair cause heart problems?

Patients have experienced chest pain, heart attack, blood clots in the lungs, weakness on one side of the body, changes in vision, and slurred speech when using Xolair.

Can Xolair cause a risk of a heart attack?

Xolair may increase the risk of heart attack, blood clots, and chest pain.

How to avoid Xolair side effects

The best way to avoid side effects is to take Xolair as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Xolair that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Xolair. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Moderate alcohol consumption is safe when treated with Xolair, but alcohol may increase your risk of side effects such as headaches or nausea.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Xolair.

7. Know the signs and symptoms of Xolair side effects

Signs and symptoms of side effects of Xolair include upper respiratory infections. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Xolair.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Xolair as needed.

Trelegy side effects and how to avoid them

Trelegy Ellipta is an FDA-approved medication manufactured by GlaxoSmithKline (GSK). It is classified as an ICS, LABA, and anticholinergic bronchodilator and is used to treat asthma and COPD. While Trelegy Ellipta is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Trelegy Ellipta include sore throats and cough. Less common, but more serious side effects, can include glaucoma and cataracts.

Learn more about the side effects of Trelegy Ellipta and what you can do to avoid them.

What is Trelegy Ellipta?

Approval of Trelegy Ellipta is based on clinical trials showing it improved lung function, COPD exacerbations, and quality of life more than AstraZeneca’s long-established two-drug inhaler Symbicort.

Trelegy Ellipta is an inhaled medication prescribed to adults to reduce the daily symptoms and the likelihood of flare-ups of asthma and chronic obstructive pulmonary disease (COPD). It helps to reduce inflammation and relax your airways and lungs, opening them up and making it easier for you to breathe. Trelegy combines three active ingredients called fluticasone furoate, umeclidinium, and vilanterol. They work together to help you breathe more easily and to reduce your asthma and COPD symptoms.

Fluticasone furoate is an inhaled corticosteroid (ICS) that reduces inflammation in your airways and lungs. It works by attaching to the surface of cells in your airways and lungs at sites called glucocorticoid receptors. This stimulates the receptors, making the cells produce less of the substances that trigger inflammation and more of the substances that reduce inflammation.

Umeclidinium is an anticholinergic bronchodilator, also known as a long-acting muscarinic antagonist (LAMA), that relaxes the muscles in your airways and lungs. It works by attaching to muscarinic receptors on the surface of your muscle cells. This blocks the receptors, stopping them from being stimulated, causing your muscle tissue to relax, and opening up your airways and lungs.

Vilanterol is classed as a long-acting beta2-agonist (LABA). It also helps to relax the muscle tissue in your airways and lungs. It attaches to receptors on the surface of your muscle tissue called beta-adrenoreceptors, which stimulate the receptors, causing the muscle tissue to relax.

Does Trelegy heal your lungs?

Trelegy helps improve your lung function allowing you to breathe more easily by opening the airways in your lungs, keeping these airways open, and reducing inflammation.

What is the best time of day to take Trelegy?

You can use Trelegy Ellipta at any time of the day, as long as you use it at the same time every day. Use Trelegy only once each day in any 24 hours. If you forget to take a dose of Trelegy, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at your normal time.

Does Trelegy cure asthma?

Trelegy will not cure asthma. Trelegy is a long-term treatment for the management of the symptoms of COPD, chronic bronchitis, emphysema, and asthma in adults.

Is Trelegy an antibiotic?

Trelegy Ellipta is not an antibiotic. Trelegy’s active ingredients are fluticasone furoate, an inhaled corticosteroid, umeclidinium bromide, an anticholinergic bronchodilator, and vilanterol, a LABA.

Does Trelegy help you breathe better?

Trelegy will help you breathe better, improve how well your lungs function, and prevent further flare-ups in the future. Trelegy will not help if you have sudden breathing problems such as an asthma attack and should not be used as a rescue inhaler.

Can you still work with Trelegy?

Yes. Continue using Trelegy unless your doctor tells you to stop using it. Stopping treatment suddenly without medical advice may make your symptoms worse.

What is the name of the active ingredient in Trelegy?

Trelegy Ellipta contains fluticasone furoate, an inhaled corticosteroid, umeclidinium bromide, an anticholinergic bronchodilator, and vilanterol, a LABA, as the active ingredients.

How long does it take for Trelegy to work?

Trelegy will start to work immediately after the first dose but it will take a few weeks or longer for you to feel the full benefits.

What are the most common side effects of Trelegy Ellipta?

The most common possible side effects of Trelegy Ellipta include:

  • Headaches
  • Sore throat, cough
  • Stuffy or runny nose
  • Muscle and joint pain
  • Back pain
  • Abdominal pain
  • Nausea, vomiting
  • Dry mouth
  • Diarrhea, constipation
  • Painful and frequent urination
  • Urinary tract infections
  • Fungal infections (candida/thrush) in your mouth and throat – this is less likely if you rinse your mouth out with water after taking your Trelegy Ellipta
  • Increase in upper respiratory tract infections, like the common cold, the flu, and sinus infections
  • Bronchitis
  • Changes in taste

More serious side effects of Trelegy Ellipta include:

  • Life-threatening allergic reactions including hives, rashes, itching, swelling in your face, tongue, and throat, chest pain, and shortness of breath, trouble breathing
  • An increased risk of developing pneumonia if you also have chronic obstructive pulmonary disease (COPD)
  • A weakened immune system
  • Adrenal insufficiency
  • Sudden worsening of your asthma symptoms, including asthma attacks (paradoxical bronchospasm)
  • Increased blood pressure
  • Fast heart rate and/or irregular heartbeat
  • Osteoporosis (reduced bone mineral density)
  • An increased risk of eye problems, including eye pain, glaucoma, cataracts, and blurred vision
  • Slowed rates of growth in children

If you experience any of these serious side effects, stop taking Trelegy Ellipta and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Trelegy make you tired?

Trelegy Ellipta may cause wheezing and make you feel tired. Speak to your healthcare provider if these side effects become problematic.

Do Trelegy side effects go away?

Some of the side effects of Trelegy will go away as you adjust to your treatment. Speak to your doctor about ways to reduce your side effects.

Trelegy side effects weight gain

Trelegy Ellipta does not cause weight gain.

Does Trelegy cause eye problems?

Trelegy can cause glaucoma, worsening of glaucoma, blurred vision, and cataracts. You should have eye check-ups on a regular basis when using Trelegy.

Trelegy Ellipta dosage

Trelegy Ellipta is available as an inhalation powder containing 2 strips of powder for oral inhalation. One strip contains fluticasone furoate 100 mcg and the other strip contains umeclidinium/vilanterol 62.5 mcg/25 mcg.

Trelegy is for oral inhalation only. For the maintenance treatment of COPD, inhale 1 inhalation of Trelegy Ellipta once each day.

You are advised to read the prescribing information and medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Trelegy Ellipta drug interactions

Trelegy Ellipta can interact with other medications including:

  • Anticholinergic – tiotropium, ipratropium, or aclidinium
  • Long-acting beta agonists (LABA) – salmeterol, formoterol, arformoterol, olodaterol, or indacaterol
  • Other medications that contain steroids
  • Any medications taken to treat bacterial, viral, or fungal infections, including an HIV infection, such as ketoconazole, itraconazole, ritonavir, nelfinavir, or cobicistat

Before taking Trelegy Ellipta, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Trelegy Ellipta warnings & precautions

Don’t take Trelegy Ellipta if:

  • Are allergic to the active ingredient fluticasone furoate, umeclidinium, or vilanterol
  • Are allergic to any of the other ingredients in Trelegy Ellipta
  • Have a severe milk protein allergy
  • Are taking another medication that contains long-acting beta-agonists (LABA) or an anticholinergic active ingredient
  • Are under 18 years of age

Talk to your doctor before using Trelegy Ellipta if you:

  • Have any heart problems
  • Have any problems with your immune system
  • Have any liver problems
  • Have high blood pressure
  • Suffer from seizures
  • Have diabetes
  • Have any eye problems, including cataracts or glaucoma
  • Have osteoporosis
  • Have any thyroid problems
  • Have or have ever had any problems with your adrenal glands
  • Have an active infection
  • Have recently been around someone who has measles or chickenpox
  • Have a mild to moderate milk protein allergy
  • Have any prostate or bladder problems, or problems passing urine
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Trelegy Ellipta, to make sure it is safe for you.

How to avoid Trelegy Ellipta side effects

The best way to avoid side effects is to take Trelegy Ellipta as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Trelegy Ellipta that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Trelegy Ellipta. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

It is safe to drink alcohol in moderation if you have COPD and use Trelegy Ellipta. If your symptoms of COPD or asthma become worse speak to your healthcare provider for further medical advice.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Trelegy Ellipta.

7. Know the signs and symptoms of Trelegy Ellipta side effects

Signs and symptoms of side effects include upper respiratory tract infections. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Trelegy Ellipta.

9. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Trelegy Ellipta as needed.

Alternatives to Breo Ellipta: which other asthma medications can I take?

Breo Ellipta is an FDA (U.S. Food and Drug Administration) approved medication manufactured by GlaxoSmithKline (GSK). Breo Ellipta is for adults to manage exacerbations of chronic obstructive pulmonary disease and for the treatment of asthma. It’s inhaled directly into your lungs and airways using a Breo Ellipta inhaler.

Here, we will take a look at what Breo Ellipta is, and what alternatives there are available.

What is Breo Ellipta?

Breo Ellipta is used daily to open up your airways and make breathing easier, providing relief from the symptoms of COPD and asthma. It also helps to reduce the chances and severity of the sudden onset of severe symptoms, like asthma attacks.

Breo Ellipta is not recommended for use in people with acute bronchospasm or asthma that can be managed with ICS (inhaled corticosteroids) or inhaled short-acting beta2-agonist prescription drugs such as ProAir HFA, Proventil HFA, or Ventolin HFA that contain albuterol.

Breo Ellipta contains two active ingredients, fluticasone furoate, a steroid, and vilanterol, a long-acting bronchodilator (LABA). They work together to relieve COPD and reduce your chances of having an asthma attack. When taken regularly, Breo Ellipta can ease COPD and asthma symptoms, and reduce the number and severity of asthma attacks

Is there a cheaper alternative to Breo Ellipta?

Advair contains fluticasone propionate, an anti-inflammatory, and salmeterol, a long-acting bronchodilator that work together to improve lung function. Advair is available as Advair Diskus (a dry powder inhaled by mouth), or Advair HFA, metered dose inhaler, which has an inhalation aerosol inhaled by mouth. Advair is available as the brand name and as a generic, which may mean that it will be available cheaper.

Is there a generic substitute for Breo Ellipta?

No, currently there is no generic substitute for Breo Ellipta.

Which is better Symbicort or Breo Ellipta?

Symbicort and Breo Ellipta both contain a combination of active ingredients, an inhaled corticosteroid (ICS), and a long-acting beta-agonist. Breo contains vilanterol and fluticasone and Symbicort contains formoterol and budesonide. Breo Ellipta and Symbicort both show a similar amount of improvement in lung function in asthma patients. Breo however is used once each day and has better patient adherence than Symbicort, which is used as two inhalations twice a day.

Are Trelegy Ellipta and Breo Ellipta the same?

Breo Ellipta contains two medications, fluticasone, and vilanterol. Trelegy Ellipta contains three medications, fluticasone (ICS), vilanterol LABA), and umeclidinium, an anticholinergic drug. Trelegy Ellipta is used to relieve symptoms of moderate to severe COPD (chronic obstructive pulmonary disease). Trelegy Ellipta is more effective than Breo Ellipta and reduces flare-ups and improves lung function by 15% over 1 year compared to Breo.

What other alternatives are there to Breo Ellipta?

Other alternatives to Breo Ellipta include:

  • Flovent, which contains fluticasone propionate (an inhaled corticosteroid) as the active ingredient, for the long-term treatment of asthma in patients 4 years of age and older
  • Spiriva, which contains tiotropium bromide, a long-acting bronchodilator used for the management of COPD and asthma. Spiriva is used when problems with breathing occur to stop them from deteriorating, rather than stopping them from happening
  • Dulera, which contains mometasone and formoterol, which are also classed as an ICS and a LABA

Common side effects of Breo Ellipta

The most common side effects of Breo Ellipta in clinical trials include:

  • Upper respiratory tract infections, bronchitis
  • Influenza
  • Fever, headaches
  • Sinusitis
  • A sore throat, throat pain, cough
  • Oral thrush (candidiasis) infections
  • Back pain, joint pain
  • Increased risk for high blood pressure, altered heart rate, or changes in heart rhythm.

More serious possible side effects of Breo Ellipta include

  • Severe life-threatening allergic reactions
  • Worsening breathing difficulties
  • Pneumonia

These aren’t all the side effects Breo Ellipta or Symbicort can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to a healthcare professional.

What is the cost of Breo Ellipta?

Breo Ellipta prices vary by retailer and will depend on if you buy a 30 or 60-dose inhaler. As a guide, a 60-dose Breo Ellipta disk inhaler will cost around $480.

Breo Ellipta dosage

Breo Ellipta is available as a Breo comes as a dry powder inhaler. The inhaler contains 2 foil blister strips of powder formulation for oral inhalation. One strip contains fluticasone furoate 100 or 200 mcg per blister and the other contains vilanterol 25 mcg per blister.

For the maintenance treatment of COPD use 1 inhalation of Breo Ellipta 100/25 once daily. For asthma use, 1 inhalation of Breo Ellipta 100/25 or 200/25 once daily. Breo Ellipta is a once-daily medication used to treat various respiratory issues, such as chronic bronchitis and emphysema. Breo is not a rescue inhaler and should not be used in cases of a sudden breathing problem.

Breo Ellipta drug interactions

Breo Ellipta can interact with other medications. These include:

  • Other medicines that contain a LABA (beta2-adrenergic agonist)
  • Beta-blockers
  • Diuretics
  • Strong cytochrome P450 3A4 inhibitors, like ketoconazole
  • Monoamine oxidase inhibitors
  • Tricyclic antidepressants

Breo Ellipta can interact with other medications. This can change how Breo Ellipta and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Breo Ellipta contraindications

You should not use Breo Ellipta if you:

  • Are allergic to the active ingredients fluticasone furoate or vilanterol
  • Are allergic to any of the other ingredients in Breo Ellipta
  • Have a severe allergy to milk proteins
  • Are under 18 years of age

Talk to your doctor before using Breo Ellipta if you:

  • Have any heart problems
  • Have high blood pressure
  • Have any immune system problems
  • Have a current viral, bacterial, fungal, or parasitic infection
  • Have been exposed to measles or chickenpox
  • Suffer from seizures
  • Have any thyroid problems
  • Have diabetes or high blood sugar
  • Have any liver problems
  • Have osteoporosis
  • Have any eye problems, like glaucoma, cataracts, or increased pressure in your eye
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

Please read the prescribing information provided with your medication and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Similarly, speak to your doctor if you are using Breo Ellipta and plan to stop your treatment or are thinking about switching to an alternative treatment.

Does Farxiga cause weight loss?

Obesity and being overweight affect around 70% of adults in the U.S. and are closely linked to risk factors for diabetes. Losing 5% to 10% of body weight is seen to greatly reduce the risk of cardiovascular disease in adults. Here, we will take a look at Farxiga, how it helps with weight loss, and how some of the alternative treatments for diabetes compared with it.

What is Farxiga?

Farxiga is the brand name for an FDA-approved medication manufactured by AstraZeneca. It is classed as a sodium-glucose cotransporter 2 (SGLT 2 inhibitor) inhibitor and is used to reduce high blood sugar levels in people who have type 2 diabetes. It is also used in certain people to lower the risk of hospitalization for heart failure. Farxiga is approved to be used by people with type 2 diabetes for:

  • Improving blood sugar levels when used in combination with changes to diet and exercise
  • Reducing the risk of hospitalization for heart failure in people with heart disease or risk factors for heart disease

In individuals with heart failure with or without type 2 diabetes, Farxiga is approved for reducing the risk of hospitalization for heart failure or cardiovascular death in people with reduced ejection fraction. For those with chronic kidney disease that may worsen, Farxiga is approved for reduing  the risk of:

  • Lowered glomerular filtration rate (GFR)
  • Cardiovascular death
  • Hospitalization for heart failure
  • End-stage kidney disease

The active ingredient in Farxiga is called dapagliflozin. When absorbed into your bloodstream, dapagliflozin slows down the rate at which your kidneys absorb glucose from your blood. This causes your kidneys to release sugar into your urine. Your blood glucose levels then fall as you urinate. Farxiga can be used in combination with other medications for diabetes, including insulin, metformin, or sulfonylureas to lower blood sugar or hemoglobin A1c (HbA1c) levels. Farxiga is not approved for the treatment of type 1 diabetes and should not be used to treat diabetic ketoacidosis (DKA).

What are the common side effects of Farxiga?

The most common possible side effects of Farxiga in clinical trials include:

  • Dehydration, changes in urination, dizziness, back pain
  • Constipation
  • Weight loss

Farxiga can cause more serious side effects, including:

  • Low blood sugar (hypoglycemia)
  • More serious urinary tract infections (UTI)
  • Inflammation of the pancreas (pancreatitis)
  • Diabetic ketoacidosis
  • A rare bacterial infection that damages the tissue under the skin in the area between the anus and genitals (necrotizing fasciitis)
  • Unusual tiredness, nausea, vomiting, abdominal pain, trouble breathing
  • Ketoacidosis (increased ketones in your blood or urine)
  • Increase in your cholesterol levels

If you experience any of these serious side effects, you should stop taking Farxiga and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA (Food and Drug Administration). Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Farxiga cause weight loss?

Farxiga helps you to remove sugar from your body through your urine, preventing your body from absorbing it. This may lead to weight loss.

How rapid is weight loss with Farxiga?

Individuals taking Farxiga, 5 mg or 10 mg each day have been shown to lose around 6 pounds of body weight over 6 months. This was similar to those taking Farxiga in combination with metformin.

Farxiga vs Jardiance for weight loss

Jardiance belongs to the same class of drugs as Farxiga and has similar side effects to Farxiga such as urinary tract infections and genital yeast infections. Jardiance also has a diuretic effect, similar to Farxiga. Jardiance and Farxiga both help to get rid of fluid from the body at the same time as reducing blood sugar levels.

Both drugs are effective for the treatment of heart failure with reduced ejection fraction (the blood pumped out of your heart with each heartbeat) and high blood pressure. Jardiance reduces the risk of death in patients with high cardiovascular risk and Type 2 diabetes (as does Farxiga). Farxiga is also recommended for the reduction of the risk of kidney problems and the progress of kidney disease in patients with chronic renal disease (Jardiance is not).

Jardiance causes a similar level of weight loss in individuals as does Farxiga. Neither medication is however recommended for weight loss. Speak to your doctor for medical advice about weight loss when taking either Farxiga or Jardiance.

Which is better Invokana or Farxiga?

Farxiga and Invokana (canagliflozin) are diabetes drugs with many similar side effects. However, Farxiga has been reported to increase levels of LDL cholesterol, and to increase the risk of bladder cancer which Invokana does not. Farxiga may also cause further damage to kidneys in patients already suffering from moderate to severe kidney damage.

Farxiga and metformin weight loss

Metformin causes a relatively small amount of weight loss, due to its side effects, such as decreased appetite and diarrhea. Metformin is not approved for weight loss.

Farxiga for weight loss in non-diabetics

Farxiga is not FDA-approved as a weight-loss med, but weight loss can be a side effect of the drug. You are advised to speak to your doctor before taking Farxiga for weight loss.

Why take Farxiga in the morning?

Farxiga is available as 5 mg and 10 mg tablets. For Type 2 diabetes mellitus the recommended starting dose is 5 mg once daily, taken in the morning. The dose may be increased to 10 mg once daily if 5 mg is tolerated but require additional glycemic control.

For reducing the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and cardiovascular disease or multiple cardiovascular risk factors, the recommended dose is 10 mg once daily. For heart failure, the recommended dose is 10 mg once daily.

Before taking Farxiga, tell a healthcare professional about any other medical conditions you may have, all prescription drugs, over-the-counter, and other medications you take. Also tell them about any vitamins, herbs, and supplements you use.

Does Farxiga affect appetite?

Farxiga can cause low blood glucose levels in people with diabetes, especially if they are using it in combination with other medications such as insulin or sulfonylureas. Symptoms can include increased hunger, dizziness, confusion, and sweating. Increased hunger may cause an increase in weight due to an increase in the consumption of food.

Does Farxiga cause erectile dysfunction?

No, Farxiga does not cause erectile dysfunction.

Does Farxiga cause hair loss?

Hair loss is not a side effect of Farxiga, but hair loss and hair thinning may be caused by diabetes due to high blood sugar levels.

Does dapagliflozin cause heart failure?

No, dapagliflozin reduces the risk of heart failure or cardiovascular death in patients with heart failure and reduced ejection fraction and is used to treat type 2 diabetes, heart failure and chronic kidney disease.

Does Farxiga cause cancer?

No, patients using Farxiga are more likely to develop bladder cancer than those using an alternative drug for diabetes.

Farxiga warnings & precautions

Farxiga carries a list of warnings and precautions advising when you shouldn’t use it. Don’t take Farxiga if:

  • Are allergic to the active ingredient dapagliflozin
  • Are allergic to any of the other ingredients found in Farxiga (listed in the leaflet which comes with the medication)
  • Have diabetic ketoacidosis or a history of diabetic ketoacidosis
  • Have severe kidney issues or are on dialysis
  • Are pregnant or breastfeeding – It is unknown if this drug passes into breast milk
  • Are under 18 years of age

Talk to your doctor before taking Farxiga if you:

  • Have Type 1 diabetes
  • Have liver or kidney problems
  • Have heart disease
  • Are over 65 years of age
  • Are taking medication to lower your blood pressure or have a history of low blood pressure
  • Often get urinary tract infections

You should always check with your doctor or pharmacist before taking any medication, including Farxiga, to make sure it is safe for you.

Farxiga alternatives: which other diabetes medications can I take?

Farxiga is the brand name for an FDA-approved medication manufactured by AstraZeneca. It is classed as a sodium-glucose cotransporter (SGLT2) inhibitor and is used to reduce high blood sugar levels in people who have type 2 diabetes. It is also used in certain people to lower the risk of hospitalization for heart failure. It is approved to be used in people with type 2 diabetes for:

  • Improving blood sugar levels when being used in combination with changes to diet and exercise
  • Reducing the risk of hospitalization for heart failure in people with heart disease or risk factors for heart disease

In individuals with heart failure with or without type 2 diabetes, Farxiga is approved for reducing the risk of hospitalization for heart failure or cardiovascular death in people with reduced ejection fraction. For those with chronic kidney disease that could worsen, Farxiga is approved for reducing the risk of:

  • End-stage kidney disease
  • Lowered glomerular filtration rate (GFR)
  • Hospitalization for heart failure
  • Cardiovascular death

The active ingredient in Farxiga is called dapagliflozin. When absorbed into your bloodstream, dapagliflozin slows down the rate at which your kidneys absorb glucose from your blood. This causes your kidneys to release sugar into your urine. Your blood sugar levels then fall as you urinate. Farxiga can also be used in combination with some other diabetes medications, including insulin, metformin, or a sulfonylurea.

Farxiga is not approved to treat type 1 diabetes and should not be used to treat diabetic ketoacidosis (DKA).

What are the side effects of Farxiga?

The most common possible side effects of Farxiga in clinical trials include:

  • Dehydration, changes in urination, dizziness, back pain
  • Constipation
  • Weight loss

Farxiga can cause more serious side effects, including:

  • Low blood sugar (hypoglycemia)
  • More serious urinary tract infections (UTI)
  • Inflammation of the pancreas (pancreatitis)
  • Diabetic ketoacidosis
  • A rare bacterial infection that damages the tissue under the skin in the area between the anus and genitals (necrotizing fasciitis)
  • Unusual tiredness, nausea, vomiting, abdominal pain, trouble breathing
  • Ketoacidosis (increased ketones in your blood or urine)
  • Increase in your cholesterol levels

If you experience any of these serious side effects, you should stop taking Farxiga and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA (Food and Drug Administration). Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

RELATED: Farxiga side effects and how to avoid them

What are the cheaper alternatives to Farxiga?

Alternative treatment options are available to Farxiga, some of which may be cheaper and more cost-effective to use. Glipizide is a generic alternative costing significantly less than Farxiga. Glipizide belongs to the drug class known as sulfonylureas. It is a much older treatment for diabetes, associated with side effects such as hypoglycemia (low blood sugar level), and weight gain.

Metformin is another generic drug, and probably the most well-known treatment for diabetes other than insulin. Metformin is classed as a biguanide, is also cheaper than Farxiga, and does not cause side effects such as hypoglycemia and weight gain.

Natural alternatives to Farxiga

Natural alternatives to Farxiga may include non-prescription alternatives such as herbal or homeopathic supplements. It is important to be aware however that products sold or supplied as natural remedies for the treatment of diabetes will not have undergone the same rigorous testing prescription drugs have, and may not be safe or effective when managing the symptoms of diabetes. Speak to a healthcare professional for medical advice about potential allergic reactions or drug interactions before using natural alternatives.

Changes in lifestyle such as a low-carb diet, exercise, and weight loss are the best natural way to help manage your diabetes. Speak to your doctor or dietitian for advice on creating your own personal diet plan.

Farxiga vs Jardiance

Jardiance belongs to the same class of drugs as Farxiga and has similar side effects to Farxiga such as urinary tract infections and genital yeast infections. Jardiance also has a diuretic effect, similar to Farxiga. Jardiance and Farxiga both help to get rid of fluid from the body at the same time as reducing blood sugar levels.

Both drugs are effective for the treatment of heart failure with reduced ejection fraction (the blood pumped out of your heart with each heartbeat) and high blood pressure. Jardiance reduces the risk of death in patients with high cardiovascular risk and Type 2 diabetes (as does Farxiga). Farxiga is also recommended for the reduction of the risk of kidney problems and the progress of kidney disease in patients with chronic renal disease (Jardiance is not).

RELATED: Farxiga vs Jardiance

Can Jardiance and Farxiga be taken together?

Jardiance and Farxiga are not recommended to be used together. Both drugs belong to the same class of drugs and interactions were found between Farxiga and Jardiance when taken together.

Are Farxiga and Rybelsus the same?

No. Rybelsus belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 agonists may help with weight loss and Rybelsus helps to reduce cardiovascular risk, but is not recommended for the treatment of heart failure.

Which is better Januvia or Farxiga?

Januvia is classed as a dipeptidyl peptidase-4 (DPP-4) inhibitor. Januvia does not cause side effects involving the genitals or urinary organs, and does not cause low blood pressure when standing (orthostatic hypotension) which Farxiga does. Januvia is however expensive and is not recommended for the protection of the kidneys or heart.

Is there a generic version of Farxiga?

No. Currently there is no generic equivalent of Farxiga available in the U. S.

Is Farxiga the same as Trulicity?

No. Trulicity also belongs to the class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 agonists. Trulicity is injected once-weekly for the treatment of diabetes.

Which is better Invokana or Farxiga?

Farxiga and Invokana (canagliflozin) are diabetes drugs with many similar side effects. However, Farxiga has been reported to increase levels of LDL cholesterol, and to increase the risk of bladder cancer which Invokana does not. Farxiga may also cause further damage to kidneys in patients already suffering from moderate to severe kidney damage.

Can you stop taking Farxiga suddenly?

Do not stop taking Farxiga suddenly, without speaking to your healthcare provider first. Stopping treatment suddenly may cause your condition to become worse.

What is the safest drug for type 2 diabetes?

Most healthcare professional agrre that metformin is the safest drug available for type 2 diabetes. It has been used for many years, is safe and effective, and not too expensive. Metformin is recommended as the drug of choice for diabetes by the American Diabetes Association (ADA).

What is better Ozempic or Farxiga?

Ozempic is the brand name for a glucagon-like peptide-1 receptor agonist (GLP-1 agonists), that helps to promote the release of insulin and reduce the secretion of glucagon from the liver. Ozempic may cause reduced blood glucose levels, nausea, vomiting, and diarrhea as a common side effect. Ozempic is less expensive in comparison to Farxiga and may be more cost effective.

Which is better Farxiga or metformin?

Metformin is classed as a biguanide and a first line treatment for diabetes. Metformin is less expensive and more effective than Farxiga and is more suitable for use in women who are pregnant or breastfeeding. Metformin is not recommended to be used in patients who have advanced renal disease, or gastrointestinal side effects such as diarrhea. .

How long has Farxiga been on the market?

Farxiga was approved by the FDA in 2014 for use in adults with type 2 diabetes in combination with diet and exercise.

Is Farxiga an insulin?

Farxiga is a SGLT-2 inhibitor, a once-daily treatment that makes your kidneys get rid of excess glucose through your urine. Farxiga works independently of insulin.

Avastin side effects and how to avoid them

Avastin is an FDA-approved medication manufactured by Genentech, Inc., used to treat different types of cancers. While Avastin is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Avastin include headaches and back pain. Less common, but more serious side effects, can include high blood pressure.

Learn more about the side effects of Avastin and what you can do to avoid them.

What is Avastin (bevacizumab)?

Avastin is a cancer medication that’s prescribed to adults for the treatment of a range of cancers, including:

  • Metastatic colorectal cancer
  • Non-squamous non-small cell lung cancer
  • Recurrent glioblastoma
  • Metastatic renal cell carcinoma
  • Epithelial ovarian cancer
  • Fallopian tube cancer
  • Primary peritoneal cancer
  • Hepatocellular Carcinoma

What does Avastin do to your body?

The active ingredient in Avastin is called bevacizumab. It’s a type of biologic medication called a monoclonal antibody. This is a cancer-fighting protein designed to target and starve cancerous tumors of blood. When Avastin is given to you, the bevacizumab it contains is absorbed into the cancerous cells that make up your tumor(s). It then blocks a protein inside your cancerous cells called vascular endothelial growth factor A (VEGF-A).

VEGF-A is used by cancerous cells to create new blood vessels. This helps cancerous tumors create their own blood supply, which they need to receive the blood, and the oxygen and nutrients it contains, for the tumor to survive and grow. However, by blocking VEGF-A, bevacizumab stops your tumors(s) from creating their own blood supply, starving them of blood, oxygen, and nutrients. This makes it harder for the tumors to grow and makes them easier to kill with other cancer treatments, like chemotherapy.

Avastin dosage

Avastin is available in injection form in the following doses: 100 mg/4 mL or 400 mg/16 mL in single-dose vials.

Avastin is often prescribed alongside other cancer treatments, most often chemotherapy. The medication is given to you by intravenous infusion directly into a vein, usually at the same time as chemotherapy medications are administered by intravenous infusion. The amount of Avastin you require, how often you’ll need to take it, and what other treatments you’ll need will be decided upon by the prescribing doctor based on your cancer and your medical history.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Avastin?

The most common possible side effects of Avastin include:

  • Dry mouth, cough, sore throat, changes in your voice changes
  • Loss of appetite, diarrhea, vomiting, constipation
  • Mouth ulcers
  • Headaches
  • Watery eyes
  • Dry skin
  • Nosebleeds
  • Back pain
  • Changes in taste
  • An increased risk of bleeding
  • Inflammation of the nose
  • Inflammation of the skin
  • High blood pressure

Avastin can cause more serious side effects, including:

  • Dizziness, feeling light-headed, short of breath, sweating, chest pain, swelling in your face. These side effects may occur when you receive your injection
  • An increased risk of blood clots that can cause heart attacks, strokes, and pulmonary embolism
  • Heart failure – symptoms include swelling of your ankles and feet, tiredness, sudden weight gain
  • Posterior reversible encephalopathy syndrome (a brain condition)
  • Gastrointestinal perforations, tears, and holes in your digestive tract that can cause pain, bloody or tarry stools, vomit that looks like coffee grounds, constipation, and fever
  • Kidney problems that can reduce kidney function and that can cause fatal kidney failure in severe cases
  • The development of abnormal holes and passaged inside your body called fistula, which can be fatal in severe cases
  • Severe high blood pressure (hypertension)
  • Reduced white blood cells
  • Impaired healing of wounds and surgical procedures
  • Eye problems, including loss of vision
  • Severe allergic reactions including anaphylaxis
  • Damage to your ovaries if you’re a woman with ovaries, leading to ovarian failure in severe cases

If you experience any of these serious side effects, stop taking Avastin and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Are there any long-term side effects of Avastin?

Long-term side effects of Avastin include heart failure, hypertension, stroke, GI perforation, kidney problems, problems with wound healing, or early menopause. These side effects may continue even after you have stopped Avastin treatment.

How long do Avastin side effects last?

Avastin may remain in your system for around 4 months even after you have stopped using it. You may continue to experience certain side effects even after you have stopped treatment. Also, some side effects may reduce while you are still receiving treatment with Avastin. Speak to your doctor for medical advice if you are concerned.

Avastin drug interactions

Sometimes, medications can interact with each other. When this occurs, it can change how the medications work. Some side effects can also become more likely. Tell your prescribing doctor about all drugs you’re taking, including vitamins, and herbal and dietary supplements.

Avastin warnings & precautions

Avastin can harm an unborn baby. Talk to your doctor about taking Avastin if you’re pregnant or plan to become pregnant. Talk to your doctor about effective birth control if you want to take Avastin and you’re a woman who can become pregnant.

Don’t take Avastin if you:

  • Are allergic to the active ingredient bevacizumab
  • Are allergic to any of the other ingredients in Avastin
  • Are under the age of 18

Talk to your doctor before taking Avastin if you:

  • Are due to have surgery
  • Due to have any kind of immunization or vaccination
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Avastin, to make sure it is safe for you.

What is the life expectancy after using Avastin?

Avastin may increase life expectancy by around 4 months.

Does Avastin cause joint pain?

Joint pain may occur while being treated with Avastin. Joint stiffness and swelling may occur at the same time as joint pain.

Does Avastin cause colon cancer?

Avastin does not cause colon cancer. Avastin is actually used to treat many different types of cancer including colon cancer.

Why was Avastin taken off the market?

Avastin was taken off the market as its risks were found to outweigh its benefits. It can however be prescribed off-label by your doctor. Off-label means it is not approved by the FDA (Food and Drug Administration).

How do you feel after an Avastin infusion?

Avastin may cause life-threatening infusion-related reactions. Symptoms may include fever, chills, dizziness, feeling light-headed or faint, trouble breathing, itching, or rash.

What kind of cancer is Avastin used for?

Avastin is used to treat a range of cancers affecting different parts of the body. This includes the lungs, liver, kidney, colon, cervix, fallopian tubes, and ovaries.

How long can you stay on Avastin?

Treatment with Avastin will usually continue for as long as it is effective in controlling your cancer.

How to avoid Avastin side effects

The best way to avoid side effects is to take Avastin as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Avastin that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Avastin. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol does not affect Avastin but may affect other medications Avastin is used in combination with. You are advised to avoid drinking alcohol while taking Avastin as it can increase your risk of side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Avastin.

7. Know the signs and symptoms of Avastin side effects

Signs and symptoms of side effects include headaches, dizziness, and feeling faint. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Avastin may cause weight gain or weight loss. If you experience this side while taking Avastin, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Avastin.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Avastin as needed.

Wixela side effects and how to avoid them

Wixela Inhub is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Mylan Pharma. It contains two ingredients, fluticasone propionate an inhaled corticosteroid (ICS), and salmeterol xinafoate, a long-acting beta-agonist (LABA), also known as a bronchodilator. It is used to treat asthma and COPD. While Wixela is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Wixela include sore throats and thrush. Less common, but more serious side effects, can include high blood pressure and osteoporosis.

Learn more about the side effects of Wixela and what you can do to avoid them.

What is Wixela (fluticasone/salmeterol)?

Wixela Inhub is used:

  • For the maintenance treatment of asthma and to prevent symptoms such as wheezing in patients 4 years of age and older
  • To treat adults and children with asthma who are not well controlled with an asthma control medicine, such as an inhaled corticosteroid (ICS) and need both an ICS and a long-acting beta-2-adrenergic agonist (LABA) medicine
  • For the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both
  • To reduce exacerbations of COPD in patients with a history of exacerbations

Wixela Inhub does not work right away and should not be used to relieve intense flare-ups of shortness of breath, sudden asthma attacks, or bronchospasm. If an asthma attack occurs, use your quick-relief aerosol inhaler.

RELATED: What is Wixela Inhub

Wixela dosage

Wixela Inhub (fluticasone/salmeterol) is available as a dry powder inhaler (DPI) containing a combination of fluticasone propionate (100, 250, or 500 mcg) and salmeterol inhalation powder formulation for oral inhalation.

Wixela Inhub is used twice a day. The recommended starting dose is based on the severity of your asthma. You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: Wixela Inhub Dosage

What are the side effects of Wixela?

The most common side effects of Wixela Inhub in clinical trials include:

  • Headache
  • Upset stomach, vomiting
  • Sore throat, thrush (fungal infection of the throat)
  • Signs of a common cold

More serious side effects of Wixela Inhub include:

  • Worsening of existing infections
  • Allergic reactions – hives, swollen, blistered, or peeling skin with or without fever, wheezing, tight chest or throat, problems breathing, swallowing, or talking, unusual hoarseness, swelling of the mouth, face, lips, tongue, or throat
  • Upper respiratory tract infection, nasal sinus disorders
  • High blood sugar – confusion, feeling sleepy, increased thirst, increased urination, fruity smell to the breath
  • Signs of low potassium (hypokalemia) – muscle pain or weakness, muscle cramps, irregular heartbeat
  • High blood pressure or low blood pressure
  • Chest pain or pressure
  • Feeling anxious
  • Eye problems including glaucoma, cataracts, or other changes in vision
  • Seizures
  • Bone thinning or weakness (osteoporosis)
  • Insomnia
  • Tiredness
  • Vaginal itching or discharge
  • Weight gain
  • Red or white patches in the mouth or throat
  • Breathing problems – if you have trouble breathing, breathing that is worse, shortness of breath, wheezing or coughing after using Wixela Inhub use a rescue inhaler containing albuterol and get medical help right away

If you experience any of these serious side effects, stop taking Wixela and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Are there any long-term side effects of Wixela?

Long-term use of steroids may slow growth in children and young adults. You should use the lowest dose needed to manage your symptoms of asthma or COPD. Speak to your doctor for further medical advice.

Wixela drug interactions

Wixela can interact with other medications including:

  • Other long-acting beta-2 agonists
  • Antivirals – ritonavir, atazanavir, indinavir, saquinavir
  • Antifungals – ketoconazole, itraconazole
  • Antibiotics – clarithromycin, telithromycin
  • Tricyclic antidepressants, and monoamine oxidase inhibitors (MAOIs)
  • Beta-blockers
  • Diuretics

Before taking Wixela, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Wixela warnings & precautions

You should not use Wixela Inhub if you:

  • Are allergic to the active ingredients fluticasone propionate or salmeterol xinafolate
  • Have a known hypersensitivity to any of the other ingredients in Wixela Inhub
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Wixela Inhub if you:

  • Are taking any of the medications that could interact with Wixela Inhub
  • Are breastfeeding or are planning to breastfeed
  • Are using another drug similar to this one
  • Have diabetes
  • Have osteoporosis
  • Have an allergy to milk proteins
  • Have been in contact with anyone who has an infection such as chickenpox, measles, or flu

You should always check with your doctor or pharmacist before taking any medication, including Wixela, to make sure it is safe for you.

Who should not use Wixela?

Those with an allergy to the active and inactive ingredients, and anyone pregnant or planning to become pregnant should not use Wixela. Speak to your healthcare provider to discuss alternative treatments.

Can Wixela cause weight gain?

Yes, Wixela may cause some weight gain.

Does Wixela cause high blood pressure?

Wixela may increase your blood pressure. Monitor your blood pressure and speak to your doctor if your blood pressure is high.

Can Wixela be used long-term?

Salmeterol and fluticasone, the active ingredients in Wixela are designed to be used for long-term use. They are not to be used as rescue treatment. Discard your Wixela device safely if you have not used up all of your doses within one month of opening the foil package it is supplied in.

Does Wixela cause nausea?

Nausea is a common side effect of Wixela. Other common side effects include upper respiratory tract infection, bronchitis, thrush, throat irritation, coughing, changes in your voice, and hoarseness.

How long does it take for Wixela to work?

The effects of Wixela may take 1 week or more to be seen before you experience the maximum benefits of this treatment. Speak to your healthcare provider if your symptoms of asthma or COPD do not improve or get worse.

How to avoid Wixela side effects

The best way to avoid side effects is to take Wixela as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Wixela that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Wixela. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is not known to interact with the ingredients in Wixela. You are advised however to limit your alcohol consumption as it can increase your risk of side effects. Also, avoid smoking as this will make your symptoms of asthma or COPD worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Wixela.

7. Know the signs and symptoms of Wixela side effects

Signs and symptoms of side effects include sore throats, coughing, and thrush. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Wixela may cause weight gain. If you experience this side effect while taking Wixela, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Wixela.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Wixela as needed.

Foods to avoid while taking Cymbalta

Unless your healthcare provider instructs you to avoid certain foods, it is ok to stick to your regular diet while taking Cymbalta.

Cymbalta is the brand name for an FDA-approved (Food and Drug Administration) antidepressant medication. It’s prescribed to treat mental health disorders such as major depressive disorder in adults, as well as generalized anxiety disorder, fibromyalgia, diabetic peripheral neuropathic pain (chronic pain), and chronic musculoskeletal pain.

The active ingredient in Cymbalta is called duloxetine, a type of antidepressant called a serotonin-norepinephrine reuptake inhibitor (SNRI). Usually, any excess serotonin and norepinephrine is quickly re-absorbed by the neurons that create it. Duloxetine stops this happening (reuptake inhibition), causing concentrations of serotonin and norepinephrine to build up in the brain. These chemicals influence your thoughts, mood, and emotions, and increasing their levels is associated with a reduction in depression and anxiety.

Cymbalta also works as an analgesic, reducing the pain you feel. It likely does this by reducing the sensitivity of your nerves to pain and by blocking the way pain signals are sent around your body.

How do I know if Cymbalta is working?

Improvement in sleep, appetite, or energy may be seen within the first couple of weeks of treatment with Cymbalta. These improvements in symptoms are an early sign that the treatment is working. It may take up to 2 months to see an improvement in mood or a lack of interest in daily activities.

What are the side effects of Cymbalta?

The most common side effects of Cymbalta in clinical trials include:

  • Headaches
  • Drowsiness
  • Nausea
  • Dry mouth
  • Lack of appetite
  • Insomnia
  • Reduced sex drive, and problems orgasming

More serious side effects of Cymbalta include:

  • Increased risk of suicidal thoughts and behaviors
  • Sudden changes in mood or behavior – anxiety, trouble sleeping, irritable, aggressive, restless
  • Allergic reactions to the medication – hives, trouble breathing, swelling of your face, lips, mouth or throat, severe skin reactions, fever, skin rash, skin pain, sore throat, and burning eyes
  • High blood pressure
  • Liver failure

These aren’t all the side effects Cymbalta may cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about adverse effects, talk to your physician or pharmacist. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

What are the long-term side effects of Cymbalta?

Long-term side effects of Cymbalta are associated with what is known as discontinuation syndrome after the last dose of Cymbalta leaves the body. These symptoms can be life-threatening.

Cymbalta can cause withdrawal symptoms, suicidal thoughts and behaviors, especially in teenagers and young adults. Patients are advised to consult their doctor on how to taper down their dose safely before stopping treatment with Cymbalta.

Stopping treatment with Cymbalta suddenly may cause the re-emergence of symptoms such as confusion, dizziness, headaches, mood swings, increased thoughts of suicide, and general tiredness. Cymbalta withdrawal symptoms may also occur, these include seizures, nausea, vomiting, nightmares, muscles aches, and sexual dysfunction.

Long-term side effects may continue for weeks or months after stopping treatment with Cymbalta, regardless of whether Cymbalta has left your system or not.

What are Cymbalta side effects in females?

Side effects in females are the same as they are for males. Common side effects will include drowsiness, dry mouth, nausea, loss of appetite, and constipation. More serious side effects will include feeling light headed or faint, unusual bleeding, changes in vision, painful or difficult urination, liver problems, low blood sodium, and manic episodes.

Females may have symptoms of serotonin syndrome, such as hallucinations, agitation, sweating, fever, increased heart rate, loss of coordination, muscle twitching or stiffness, nausea, and vomiting.

Cymbalta warnings & precautions

Don’t take Cymbalta if you:

  • Are allergic to the active ingredient duloxetine
  • Are allergic to any of the other ingredients in Cymbalta (listed in the leaflet which comes with the medication)
  • Have liver disease
  • Have a severe kidney disease
  • Are under 18 years of age

Talk to a healthcare professional about your medical condition before taking Cymbalta if you:

  • Have previously had thoughts about harming yourself or committing suicide
  • Have kidney disease
  • Have ever had fits or seizures
  • Have ever experienced mania
  • Have bipolar disorder
  • Have any eye problems, including any kind of glaucoma
  • Have any bleeding disorders
  • Are at risk of having low sodium levels, for instance, if you’re taking diuretics
  • Are intolerant to some sugars
  • Are under 25 years of age
  • Are pregnant or trying to become pregnant
  • Are breastfeeding or plan to breastfeed

Can you drink caffeine with Cymbalta?

Consuming drinks high in caffeine such as coffee can increase your risk of developing serotonin syndrome. Symptoms would include hallucinations, agitation, sweating, fever, increased heart rate, loss of coordination, muscle twitching or stiffness, nausea, and vomiting.

What does Cymbalta do to your stomach?

Cymbalta may cause abdominal pain but this is not a common side effect. Pain in the stomach area could be a sign of liver problems.

Does Cymbalta cause weight gain?

Weight loss is more common with Cymbalta than weight gain in the first 8 to 9 weeks of Cymbalta treatment, with some weight gain possible after 8 months of treatment. Weight loss may be due to side effects such as nausea or loss of appetite. Speak to your healthcare provider for medical advice.

Can I have a glass of wine while taking Cymbalta?

Drinking alcohol is not advised while taking Cymbalta. Alcohol consumption may increase your risk of liver damage, worsen side effects and make Cymbalta less effective for the treatment of anxiety or depression.

Does Cymbalta affect appetite?

Decreased appetite and weight loss is commonly associated with serotonin and norepinephrine reuptake inhibitors such as Cymbalta due to gastrointestinal side effects.

Who should not take Cymbalta?

Do not take Cymbalta if you:

  • Have a heart problem
  • Are taking or have taken medicines for depression within the last 14 days
  • Have glaucoma
  • Have had a seizure, manic episodes, or bipolar disorder
  • Are allergic to the active ingredient duloxetine
  • Are allergic to any of the other ingredients in Cymbalta
  • Have liver disease
  • Have a severe kidney disease
  • Are under 18 years of age

How to lose weight while taking Cymbalta

Cymbalta has been seen to cause a small amount of weight loss in the first few weeks of treatment. Maintaining a healthy well balanced diet, rich in fruits and vegetable, and low in fatty foods high in salt or sugar, as well as physical activity such as exercise is the best way to lose weight while taking Cymbalta.

What should I avoid while taking Cymbalta?

You do not need to avoid any particular foods while taking Cymbalta. However, avoid MAO inhibitors such as isocarboxazid, metaxalone, moclobemide, phenelzine, rasagiline, and tranylcypromine during treatment with Cymbalta.

Is it best to take Cymbalta at night or morning?

Cymbalta may be taken at any time of day, as long as you take it at the same time each day.

What can I eat when taking Cymbalta?

You can continue with your diet as normal as there are no interactions of any food types with Cymbalta.

Cymbalta drug interactions

Cymbalta can interact with other medications. These include:

  • Other medications that can increase serotonin levels, like other SSRI and SNRI antidepressants, tramadol, tryptophan, or St John’s Wort
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Medicines that cause sleepiness, like strong painkillers, benzodiazepines, antipsychotics, phenobarbital, and antihistamines
  • NSAIDs (nonsteroidal anti-inflammatory drugs) such as aspirin, ibuprofen, or naproxen
  • Medicines that thin your blood or prevent it from clotting, like anticoagulants or antiplatelet agents such as warfarin

When Cymbalta is taken with other medicines, they may interact and change how those work. It may also increase the severity and frequency of certain side effects. Make sure your healthcare provider is aware of all the medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Does Januvia cause weight loss?

Januvia is the brand name for an FDA (U.S. Food and Drug Administration) approved medication manufactured by Merck. Januvia is a diabetes drug used to treat type 2 diabetes mellitus. It helps to lower blood sugar levels when used in combination with exercise and changes to your diet. Januvia may be used alone or in combination with other diabetes medications, such as metformin, glimepiride, glipizide, pioglitazone, or insulin.

If you have type 2 diabetes, your body may not produce enough insulin or may become resistant to the effects of insulin. This means less sugar is removed from your blood and your blood sugar levels stay too high. High blood sugar levels can cause a range of problems over time, including nerve damage, heart disease, strokes, and kidney failure. Januvia encourages your pancreas to produce insulin for longer after you’ve eaten, helping your body absorb more sugar out of your blood.

Obesity and being overweight are serious health conditions associated with diabetes, and losing 5 to 10% of your body weight will greatly reduce your risk of cardiovascular disease. Here, we will look at what effect Januvia has on your body weight.

Are there any side effects to Januvia?

The most common side effects of Januvia in clinical trials compared to placebo include:

  • Increase in upper respiratory infections and the common cold (stuffy or runny nose and sore throat)
  • Headaches
  • Hypoglycemia (low blood sugar levels)
  • Vomiting
  • Constipation

More serious side effects of Januvia include

  • Severe joint pain
  • Pancreatitis (inflammation of the pancreas)
  • Kidney disease, and kidney failure
  • Serious allergic reactions including anaphylaxis – symptoms include a low pulse, sudden drop in blood pressure, and shortness of breath

These aren’t all the side effects Januvia can cause. You can find more details in the patient leaflet that comes with your medication. Talk to your physician or pharmacist if you have any concerns about side effects. You are encouraged to report the side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Januvia drug interactions

Januvia can interact with other medications. These include:

  • Other medications that can lower blood sugar levels, like insulin or a sulfonylurea medicine
  • Digoxin – used to treat a range of heart conditions

Januvia can interact with other medications. This can change how Januvia and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Januvia contraindications

You should not use Januvia if you:

  • Are allergic to the active ingredient sitagliptin
  • Are allergic to any of the other ingredients in Januvia
  • Have type 1 diabetes
  • Are under 18 years of age

Talk to your doctor about your medical conditions before using Januvia if you:

  • Have a history of pancreatitis (inflammation of the pancreas)
  • Have a heart condition
  • Have kidney disease or any other renal/kidney problems
  • Are over 65 years of age
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Does Januvia cause weight loss?

Januvia does not cause weight gain or weight loss as a side effect.

Januvia and metformin for weight loss

Januvia may cause weight loss when taken in combination with metformin. It has been determined that patients that have taken Januvia had a small but otherwise insignificant reduction in body weight.

How much weight do you lose on Januvia?

Weight loss has not been reported as a side effect of Januvia. However, one clinical study in people with high cholesterol taking Januvia for the treatment of type 2 diabetes showed a reduction of around 18 lbs of body weight after 3 months of treatment.

Speak to your healthcare provider for medical advice if you are taking Januvia and want to lose weight. You may need to adjust your diet and lifestyle depending on what you need. You should consider speaking to a dietitian to develop a diet plan.

Can you lose weight while taking Januvia?

Weight loss is not a side effect of Januvia and has not been reported in clinical trials. Losing weight will have a beneficial effect on your general health if you are being treated for diabetes.

Does Januvia cause loss of appetite?

Loss of appetite is a common side effect when taking Januvia.

Which diabetes medicines cause weight loss?

Glucagon-like peptide 1 (GLP-1) agonists are a class of medication that are used to treat type 2 diabetes. These drugs help to reduce blood sugar levels and cause weight loss. These include Trulicity (dulaglutide), Ozempic (semaglutide), and Victoza (liraglutide). GLP-1 medications may cause a weight loss of around 10 to 16 pounds when using liraglutide. People using semaglutide and making changes to their lifestyle lose around 3 pounds, compared to 6 pounds in those who didn’t use the drug.

Sodium glucose cotransporter 2 (SGLT-2) inhibitors are another type of drug class that will reduce blood sugar levels and cause weight loss. These include Invokana, Steglatro, Farxiga and Jardiance.

Is it safe to drink alcohol with Januvia?

Both hypoglycemia and hyperglycemia may occur when consuming alcohol. Alcohol should be avoided if you are diabetic and have high levels of triglycerides, nerve damage, or pancreatitis. Blood glucose levels are not affected if your diabetes is under control and your alcohol consumption is moderate. Do not drink alcohol on an empty stomach or after exercise, as this could increase your risk of hypoglycemia.

What foods should be eaten when taking Januvia?

A general healthy well balanced diet should be maintained while taking Januvia for diabetes treatment. This should be high in fruits and vegetables and low in greasy fast food, high in salt or sugar.

How long does it take for Januvia to work?

Januvia works within 1 to 2 weeks to lower blood sugar. However, the full effect of Januvia will take a few months.

Does Januvia cause heart disease?

Common side effects of Januvia include headache and flu-like symptoms. More serious side effects of Januvia include lactic acidosis, heart failure and pancreatitis.

What type of diabetes does Januvia treat?

Januvia is a once-daily treatment used in combination with diet and exercise to lower blood sugar levels in patients with Type 2 diabetes. Januvia is not recommended for type 1 diabetes or for the treatment of patients with diabetic ketoacidosis.

How is Januvia different from metformin?

Januvia is a DPP-4 inhibitor (dipeptidyl peptidase-4) which increases the release of insulin from the pancreas. Metformin reduces the production of glucose by the liver. Each of these drugs works in a different way to reduce high blood sugar levels.

Biktarvy side effects and how to avoid them

Biktarvy is a brand-name medication manufactured by Gilead Sciences, Inc. (GSI), used to treat HIV (human immunodeficiency virus). While Biktarvy is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Biktarvy include stomach pain and loss of appetite. Less common, but more serious side effects, can include lactic acidosis.

Learn more about the side effects of Biktarvy and what you can do to avoid them.

What is Biktarvy?

Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) is a complete HIV treatment used to treat HIV infection in adults, and children with a weight of at least 55 pounds (25kg).

If you or your child have an HIV-1 infection, your doctor may have prescribed Biktarvy to treat it. Biktarvy can’t cure an HIV-1 infection, but it can help to reduce how much of the virus you or your child have in your body (viral load), limiting the damage it can do to your or your child’s immune system.

Biktarvy contains three active ingredients: bictegravir (BIC), emtricitabine (FTC), and tenofovir alafenamide (TAF). They are each an antiviral drug that can stop the spread of the HIV-1 virus through your T-cells.

When the HIV-1 virus invades your T-cells, it inserts itself into the DNA. The virus then takes advantage of the cell’s natural DNA copying process to reproduce itself. As more copies of the virus are made, eventually the T-cell dies, and the viruses spread to other T-cells, continuing the cycle. Biktarvy helps to stop this from happening.

Bictegravir, emtricitabine, and tenofovir alafenamide each interrupt a step in the DNA copying process that the HIV-1 virus exploits to copy itself. They do this by blocking different enzymes involved in the copying process. This makes it harder for the virus to multiply, limiting the amount of virus you have in your body (your viral load).

Biktarvy dosage

Biktarvy is available in tablet form in the following doses: 50 mg BIC, 200 mg FTC, and 25 mg TAF, and 30 mg BIC, 120 mg FTC, and 15 mg TAF.

You take Biktarvy as a tablet with or without food, usually once a day. If you take a supplement containing iron or calcium, take it at the same time as your Biktarvy. If you take antacids containing aluminum or magnesium, take these 2 hours before or 6 hours after you take Biktarvy. If you miss a dose of Biktarvy take it as soon as you remember, but do not take the missed dose if it is nearly time for your next dose. Store Biktarvy tablets at room temperature, away from heat and moisture.

If have had hepatitis B (HBV) in the past, it may become active after you stop using Biktarvy. You will need regular liver function tests while using Biktarvy and for a few months after stopping treatment.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Biktarvy?

The most common possible side effects of Biktarvy include:

  • Headaches
  • Nausea
  • Stomach pain
  • Loss of appetite
  • Tiredness
  • Diarrhea

Biktarvy can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • A worsening or reemergence of an existing hepatitis B virus infection if you have or previously have had one
  • New or worsening kidney problems, including kidney failure
  • Severe liver problems, including liver failure (yellowing of your skin or eyes, upper right-sided abdominal pain)
  • Too much lactic acid in your blood (lactic acidosis), can cause serious health problems and can be fatal. Symptoms include muscle pain, a numb feeling, stomach pain, trouble breathing,  dizziness, or feeling weak or tired
  • Strengthening of your immune system (immune reconstitution syndrome) – your immune system may fight infections that have been hidden in your body for a long time

If you experience any of these serious side effects, stop taking Biktarvy and seek medical attention immediately. You are recommended to report any negative side effects of this medication to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Biktarvy?

Long-term side effects may include liver damage, depression, or worsening kidney problems.

Biktarvy drug interactions

Biktarvy can interact with other medications. This can change how Biktarvy and the other medications work and can make some side effects more likely. Tell your prescribing doctor about all drugs you’re taking, including vitamins, antacids, and herbal and dietary supplements, particularly:

  • An antiarrhythmic agent called dofetilide, used to treat a range of heart rhythm and heart rate problems
  • Rifamycins such as rifampin, rifabutin, and rifapentine
  • St. John’s wort
  • Treatments for seizures such as carbamazepine, and phenytoin

Biktarvy warnings & precautions

Biktarvy should not be used to treat HIV-1 infection in children who weigh less than 55 pounds (25kg). Don’t take Biktarvy if you:

  • Are allergic to the active ingredients bictegravir, emtricitabine, or tenofovir alafenamide
  • Are allergic to any of the other ingredients in Biktarvy
  • Are allergic to any other form of tenofovir

Talk to your doctor before starting to take Biktarvy if you:

  • Are taking any of the medications that could interact with Biktarvy
  • Have or have ever had a hepatitis B infection
  • Have any liver problems
  • Have kidney diseases or any other kidney problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is unknown if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Biktarvy, to make sure it is safe for you.

How long does Biktarvy work for?

Bictegravir has a half-life of around 17 hours. FTC and TAF have half-lives of 40 and 150 hours each. The half-life is the time it takes for half of the medication to leave your body.

Does Biktarvy cause weight gain?

Weight gain has not been reported in clinical trials for Biktarvy.

Is Biktarvy a high-risk medication?

Biktarvy can cause drug interactions, lactic acidosis, and worsening of kidney problems, including kidney failure, and liver problems.

Do Biktarvy side effects go away?

Most of the milder side effects of Biktarvy go away and do not need further medical attention. However, the more serious side effects may require further medical attention.

How does Biktarvy make you feel?

Biktarvy may cause side effects such as diarrhea, nausea, vomiting, headaches, dizziness, tiredness, and muscle pain.

Is Biktarvy a stimulant?

Biktarvy is not a stimulant. It contains a combination of antiretroviral drugs. Emtricitabine and tenofovir alafenamide belong to a drug class known as NRTIs (nucleoside reverse transcriptase inhibitors). Bictegravir is classed as an HIV integrase inhibitor.

Does Biktarvy make you feel depressed?

Depression is a less common side effect of Biktarvy. Depression with suicidal thoughts is even less common. Speak to your doctor if you experience these side effects.

How to avoid Biktarvy side effects

The best way to avoid side effects is to take Biktarvy as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Biktarvy that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Biktarvy. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol does not interact with Biktarvy. However, those with HIV, taking Biktarvy or other antiviral medication, are advised not to drink alcohol.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Biktarvy.

7. Know the signs and symptoms of Biktarvy side effects

Signs and symptoms of side effects include stomach pain and loss of appetite. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Biktarvy.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Biktarvy as needed.

Prempro side effects and how to avoid them

Prempro is a brand-name medication manufactured by Wyeth Pharmaceuticals Inc. It is classified as a hormone replacement therapy and is used to treat the symptoms of menopause. While Prempro is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Prempro include breast pain and tenderness. Less common, but more serious side effects, can include blood clots.

Learn more about the side effects of Prempro and what you can do to avoid them.

What is Prempro?

Prempro is given to women who are going through menopause or who have been through menopause. It used to treat:

  • Moderate to severe night sweats, hot flashes, and hot flushes (vasomotor symptoms) caused by the menopause
  • Moderate to severe vaginal dryness, inflammation, and pain (vaginal atrophy) caused by the menopause
  • Thinning and weakening of your bones (osteoporosis) caused by the menopause

If you’re going through menopause, or have gone through it, and you have symptoms like hot flushes and flashes, vaginal atrophy, or you are at risk of osteoporosis, your doctor may have prescribed Prempro to you. Prempro is a hormone replacement therapy that replaces lost estrogen and progesterone, easing your symptoms and reducing your risk of osteoporosis.

How does Prempro work?

Prempro contains two types of active ingredients, conjugated estrogens, and medroxyprogesterone acetate (a progestin). Conjugated estrogens are a mixture of purified versions of the hormone estrogen and medroxyprogesterone acetate is a form of the hormone progesterone. You can think of Prempro as helping to top up the estrogen and progesterone your body has lost during menopause. This helps to ease your symptoms.

Prempro dosage

Prempro is available in tablet form containing conjugated estrogens (CE) and medroxyprogesterone acetate (MPA), in the following doses: 0.3 mg CE and 1.5 mg MPA, 0.45 mg CE and 1.5 mg MPA, 0.625 mg CE and 2.5 mg MPA, 0.625 mg CE and 5 mg MPA.

Take Prempro as tablets once a day at the same time each day. You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are Prempro side effects?

The most common side effects caused by Prempro include:

  • Headaches
  • Back pain
  • Nausea, vomiting
  • Stomach pain and bloating
  • Abdominal pain
  • Fluid retention
  • Hair loss
  • Breast pain
  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • An increase in vaginal yeast infections
  • Less common side effects – menorrhagia, hematuria, urinary incontinence, urinary tract infection, and vaginal dryness

In rare instances, Prempro can cause more serious side effects, such as:

  • Severe headaches
  • Severe allergic reactions
  • An increased risk of breast cancer, ovarian cancer, or endometrial cancer
  • Enlargement of benign tumors of the uterus (called fibroids)
  • An increased risk of heart attacks, strokes, deep vein thrombosis, and pulmonary embolism – symptoms include chest pains or pains in your legs, trouble breathing, shortness of breath, weakness, and fatigue
  • An increased risk of dementia and depression
  • An increased risk of gallbladder disease
  • High blood pressure
  • High blood sugar
  • Liver problems – jaundice (yellowing of the skin or eyes)
  • Pancreatitis (inflammation of the pancreas)

If you experience any of these serious side effects, stop taking Prempro and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Prempro?

Prempro can increase the risk of heart attacks, stroke, blood clots in the legs or lungs, breast cancer, or cancer of the ovaries in postmenopausal women. The risk of side effects will depend on the strength of the HRT taken and how long it has been used.

Prempro drug interactions

Prempro can interact with other medications. When this occurs, it can change how Prempro and the other medications work, as well as make some side effects more likely. It is important to tell your prescribing doctor about all drugs you’re taking, including vitamins, and herbal and dietary supplements, particularly:

  • Any other hormone therapy medications
  • Any antibiotics taken to treat bacterial infections, including rifampin, clarithromycin, or telithromycin
  • Any antifungal medications taken to treat fungal infections, including ketoconazole and itraconazole
  • Any anticonvulsant medications taken to reduce the chances of you having seizures, like carbamazepine, phenobarbital, or phenytoin
  • Any antiviral medications you take to treat an HIV infection, including ritonavir, atazanavir, indinavir, saquinavir, or nelfinavir
  • St. John’s wort
  • Grapefruit or grapefruit juice

Prempro warnings & precautions

Prempro isn’t suitable for everyone. Don’t take Prempro if you:

  • Are allergic to estrogen
  • Are allergic to the other active ingredient called medroxyprogesterone acetate
  • Are allergic to any of the other ingredients in Prempro
  • Have unusual vaginal bleeding
  • Have or have ever had breast cancer or uterine cancer
  • Have heart diseases such as heart attack or stroke
  • Have ever had a blood clot
  • Have any liver problems
  • Are pregnant, think you are pregnant or are planning to become pregnant – using this medicine while pregnant may harm your unborn baby
  • Are not a woman who has reached the menopause

Talk to your doctor before taking Prempro if you:

  • Are taking any of the medications that could interact with Prempro
  • Have vaginal bleeding of unknown cause
  • Have a family history of angioedema
  • Have high blood pressure
  • Have diabetes
  • Have an underactive thyroid
  • Have a high or low blood calcium level
  • Have gallbladder disease
  • Suffer from seizures or epilepsy
  • Have high cholesterol or triglyceride levels, or if you are overweight
  • Are breastfeeding or are planning to breastfeed
  • Are due to have surgery or will be on bed rest

You should always check with your doctor or pharmacist before taking any medication, including Prempro, to make sure it is safe for you.

Does taking Prempro make you gain weight?

There is no evidence that Prempro will cause you to gain weight, but weight gain may occur naturally during menopause, whether you are taking HRT or not.

How long can I take Prempro?

Treatment is normally for 2 to 3 years in most women to decrease symptoms of menopause.

Do Prempro side effects go away?

Some side effects of Prempro that do not need medical attention may go away within 3 months as your body adjusts to the treatment.

Does Prempro help with mood swings?

Hormone therapy helps most women with symptoms such as hot flashes, but will also help with mood, depression, and other emotional symptoms.

Can I take Prempro with ibuprofen?

Yes, as interactions were not found to occur between Prempro and ibuprofen.

Can I take Prempro if I’m pregnant?

Do not take Prempro if you are pregnant. Speak to your doctor immediately if you believe you are pregnant.

Does Prempro make you feel better?

Prempro will help manage symptoms of menopause, such as mood, weight gain, and hot flushes, but may cause more serious side effects, such as heart attacks and stroke.

How to avoid Prempro side effects

The best way to avoid side effects is to take Prempro as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Prempro that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Prempro. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Prempro as it can increase your risk of breast cancer.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Prempro.

7. Know the signs and symptoms of Prempro side effects

Signs and symptoms of side effects include stomach pain, unusual vaginal bleeding, and breast tenderness. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Prempro may cause weight gain or weight loss. If you experience this side effect while taking Prempro, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Prempro.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Prempro as needed.

Ofev side effects and how to avoid them

Ofev is a brand-name medication manufactured by Boehringer Ingelheim Pharmaceuticals, Inc. It is classified as a tyrosine kinase inhibitor and used to treat certain lung conditions. While Ofev is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Ofev include high blood pressure. Less common, but more serious side effects, can include stomach and liver problems.

Learn more about the side effects of Ofev and what you can do to avoid them.

What is Ofev (nintedanib)?

Ofev is a medication prescribed to adults to treat:

  • A lung disease called idiopathic pulmonary fibrosis (IPF)
  • A lung disease called systemic sclerosis-associated interstitial lung disease (SSc-ILD). Interstitial lung disease causes shortness of breath and breathing more difficult
  • Long-lasting interstitial lung diseases in which lung fibrosis continues to get worse

These lung conditions can not be permanently cured but can be managed with medications like Ofev. Ofev helps to maintain your lung function, slow your decline in lung function, and reduces the risk of complications of your disease. Ofev can help you live with your condition and improve your quality of life.

How does Ofev work?

The active ingredient in Ofev is called nintedanib. It’s a type of drug called a tyrosine kinase inhibitor. Nintedanib works by blocking the action of a group of enzymes in your cells called tyrosine kinases. These enzymes start and stop various processes inside your body. When used for lung conditions, blocking tyrosine kinases slows down how much collagen your fibroblast cells produce and blocks the production of other substances that promotes collagen formation.

Always check with your doctor or pharmacist before taking any medication, including Ofev, to make sure it is safe for you.

What side effects does Ofev have?

The most common possible side effects of Ofev include:

  • Headaches
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Weight loss
  • Abdominal pain
  • High blood pressure

In rare instances, Ofev can cause more serious side effects, including:

  • Heart attacks, or other heart problems. Symptoms may include chest pain or, pain in your neck, arms, back, or jaw
  • Strokes
  • Severe allergic reactions to the medication
  • Increased levels of liver enzymes
  • Liver problems that can reduce your liver function. Your healthcare provider will carry out blood tests before and during treatment
  • An increased risk of bleeding problems
  • Tears (perforations) in your stomach or intestines
  • Serious diarrhea and vomiting

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

How do I take Ofev?

Take Ofev orally with food twice daily. Your dosage will be based on the condition you are being treated for and how you respond to treatment. Swallow Ofev capsules whole. Do not crush, chew, or open the capsules. If you miss a dose of Ofev, skip the missed dose, and take your next dose at your scheduled time. Read the full prescribing Information and drug information provided with your medication before you start taking Ofev.

Ofev drug interactions

Ofev can interact with other medications including:

  • Azole antifungal treatments such as ketoconazole
  • Medications that increase bleeding such as clopidogrel
  • NSAIDs such as ibuprofen, or naproxen
  • Blood thinners such as warfarin
  • Antibiotics such as erythromycin or rifampicin
  • Anticonvulsants such as carbamazepine or phenytoin
  • Herbal supplements such as St John’s Wort

Before taking Ofev, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Ofev warnings & precautions

Ofev can cause birth defects and the death of your unborn baby. If you’re a woman who can become pregnant, you should have a pregnancy test before taking Ofev. You should use effective birth control while taking Ofev, and for up to three months after your last dose. If you become pregnant while taking Ofev, or think you’re pregnant, contact your doctor right away.

Don’t take Ofev if you:

  • Are allergic to the active ingredient nintedanib
  • Are allergic to peanuts or soya
  • Are allergic to any of the other ingredients in Ofev
  • Are pregnant or are planning to become pregnant
  • Are under 18 years of age

Talk to your doctor before taking Ofev if you:

  • Are taking any of the medications that could interact with Ofev
  • Have any heart problems
  • Have any liver problems
  • Have a history of blood clots
  • Have recently had abdominal surgery
  • Have a history of bleeding problems or have close family members with bleeding problems
  • Are a smoker
  • Are breastfeeding or are planning to breastfeed – It is not known if Ofev passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Ofev, to make sure it is safe for you.

How long does Ofev increase life expectancy?

Patients taking Ofev had life expectancy of around three times longer than those for patients taking a placebo

Do Ofev side effects go away?

Some side effects will go away during treatment as you get used to taking the medication. Read on for some more handy tips on how to reduce your side effects.

When do Ofev side effects start?

Side effects such as liver problems are often seen within the first 3 months of treatment, but can happen at any time during treatment. Certain individuals may be at higher risk of side effects such as liver damage.

What are the benefits of taking Ofev?

Ofev helps to treat lung conditions such as idiopathic pulmonary fibrosis (IPF), and interstitial lung disease). These conditions both cause scarring and make your lungs more rigid making it more difficult for you to breathe. Ofev will help to slow the worsening of this type of lung disease.

Does Ofev affect the eyes?

Ofev may cause jaundice in some patients and cause yellowing of your eyes. Tell your doctor immediately if you notice this side effect, as it will be due to problems with your liver function.

Does Ofev cause hair loss?

Some patients have reported hair loss while using this treatment. Speak to your healthcare provider for medical advice if you experience this side effect.

How to avoid Ofev side effects

The best way to avoid side effects is to take Ofev as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Ofev that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Ofev. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Ofev. Ofev and excessive alcohol consumption can both cause liver problems.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Ofev

7. Know the signs and symptoms of Ofev side effects

Signs and symptoms of side effects of Ofev include loss of appetite and stomach pain. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Ofev may cause weight loss. If you experience this side effect while taking Ofev, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Ofev.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Ofev as needed.

Zenpep side effects and how to avoid them

Zenpep is the brand name for an FDA-approved (U.S. Food and Drug Administration) medication manufactured by Eurand Pharmaceuticals, Inc. It is a pancreatic enzyme product for the treatment of exocrine pancreatic insufficiency (EPI) associated with cystic fibrosis (CF).

While Zenpep is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Zenpep include stomach pain and flatulence. Less common, but more serious side effects, can include allergic reactions.

Learn more about the side effects of Zenpep and what you can do to avoid them.

Why do I have to take Zenpep?

Cystic fibrosis is a genetic disorder that makes your body produce fluids, like mucus, sweat, and digestive juices that are too thick. Over time this disrupts and damages parts of your body, usually your lungs, liver and kidneys, pancreas, and digestive system. The disorder can interfere with food digestion by affecting your pancreas and causing a condition called exocrine pancreatic insufficiency. Your pancreas produces digestive enzymes, which are substances that help your digestive system break down food. Thick mucus in your pancreas can block these enzymes from entering your digestive system, making it harder for you to digest food.

EPI can cause gastrointestinal problems, such as stomach cramps, bloating, pain, flatulence, and diarrhea. Problems digesting food can also mean you don’t get the calories and the nutrition you need to be healthy. It can lead to weight loss and fatigue, as well as conditions caused by dietary deficiencies like anemia, bleeding disorders, or metabolic bone disease. Zenpep helps with EPI by improving your ability to digest food. The medication contains a mixture of digestive enzymes that can help top up the enzymes you’re lacking, allowing you to digest food normally.

The active ingredient in Zenpep is called pancrelipase. Pancrelipase is a mixture of three groups of digestive enzymes called amylases, lipases, and proteases. These enzymes are derived from the pancreas of pigs, but they are safe and effective for children and adults to use. Once in your digestive system, they help your body break down and absorb the proteins, carbohydrates, sugars, and fats in your food.

How often can I take Zenpep?

Zenpep is available in a delayed-release capsule dosage form, in the following doses:

  • 5,000 USP units of lipase, 17,000 USP units of protease, 27,000 USP units of amylase
  • 10,000 USP units of lipase, 34,000 USP units of protease, and 55,000 USP units of amylase
  • 15,000 USP units of lipase, 51,000 USP units of protease, and 82,000 USP units of amylase
  • 20,000 USP units of lipase, 68,000 USP units of protease, and 109,000 USP units of amylase

Zenpep is not interchangeable with any other pancrelipase product.

  • Infants (up to 12 months) – 2,000 to 4,000 lipase units per 120 mL of formula or per breast-feeding
  • Children older than 12 months and younger than 4 years – initiate with 1,000 lipase units/kg of body weight per meal up to a maximum of 2,500 lipase units/kg of body weight per meal, or less than 4,000 lipase units/g fat ingested per day
  • Children 4 years and older and adults – begin with 500 lipase units/kg of body weight per meal to a maximum of 2,500 lipase units/kg of body weight per meal, or less than 4,000 lipase units/g fat ingested per day

For those who cannot swallow capsules whole, open the capsule and mix with applesauce. Swallow the mixture immediately. Do not chew and do not mix capsules with infant formula or breast milk. If you miss a dose of Zenpep, do not take the missed dose. Go back to your normal dosing routine. Do not double your doses.

Please see the full prescribing information and medication guide and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Zenpep?

The most common possible side effects of Zenpep in clinical trials compared to placebo-controlled trials include:

  • Abdominal pain
  • Constipation
  • Flatulence
  • Headaches

More serious side effects of Zenpep include:

  • Worsening of gout
  • Joint pain
  • Allergic reactions – hives, trouble breathing, swelling of the face, lips, tongue, or throat
  • Fibrosing colonopathy – a rare bowel disorder
  • Difficult bowel movements
  • Severe stomach pain
  • Renal cyst

These aren’t all the side effects Zenpep can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to your physician or pharmacist. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

Do Zenpep side effects go away?

Some side effects of Zenpep that do not need medical attention may go away as your body adjusts to treatment.

How long does it take for Zenpep to work?

Zenpep can begin to work within 15 minutes of being taken.

What happens if you take Zenpep and you don’t need it?

Excess pancreatic enzymes not needed will pass through your body. One or two extra capsules than needed will not be a problem. Taking lots more than needed may cause itching around your anus.

What can I take instead of Zenpep?

Alternative treatments to Zenpep include Creon, Palcaps, Pancreaze, Pancrelipase, Pertzye, and Viokace. Speak to your healthcare provider if you are considering changing your treatment.

What happens if you take too much Zenpep?

Excess pancreatic enzymes not needed will pass through your body. One or two extra capsules than needed will not be a problem. Taking lots more than needed may cause itching around your anus.

Is Zenpep addictive?

Zenpep is not addictive and reports of withdrawal symptoms have been reported in very low numbers.

Does Zenpep cause weight gain?

Zenpep does not cause weight gain, in fact, it has actually been seen to cause a slight decrease in weight.

Zenpep drug interactions

Zenpep can interact with other medications. These include:

  • Calcium carbonate
  • Ferrous fumarate, ferrous gluconate, ferrous sulfate
  • Folic acid
  • Multivitamins with iron, multivitamins with iron and fluoride, and multivitamins with minerals
  • Sodium bicarbonate

Zenpep contraindications

You should not use Zenpep if you:

  • Are allergic to pork or any pig products
  • Are allergic to any of the other ingredients in Zenpep

Talk to your doctor before using Zenpep if you:

  • Have kidney disease, gout, or high blood uric acid levels (hyperuricemia)
  • Have ever had a blockage in your intestines
  • Have problems swallowing tablets
  • Have ever had scarring or thickening of your bowel wall (fibrosing colonopathy)
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

How to avoid Zenpep side effects

The best way to avoid side effects is to take Zenpep as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Zenpep that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Zenpep. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Interactions between alcohol and Zenpep have not been reported, however you should drink in moderation when taking Zenpep to reduce the risk of side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Zenpep.

7. Know the signs and symptoms of Zenpep side effects

Signs and symptoms of side effects include nausea, stomach pain, and flatulence. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Zenpep.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Zenpep as needed.

Nucala side effects and how to avoid them

Nucala is the brand name for an FDA-approved medication manufactured by GlaxoSmithKline (GSK) taken to reduce symptoms and prevent flare-ups of the following inflammatory autoimmune disorders:

  • Asthma in adults and children 6 years of age and over (Nucala is an add-on maintenance treatment for patients with severe eosinophilic asthma)
  • Eosinophilic granulomatosis with polyangiitis (EGPA) in adults
  • Hypereosinophilic syndrome (HES) in adults and children aged 12 years and over

While Nucala is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Nucala include injection site reactions. Less common, but more serious side effects, can include severe allergic reactions.

Learn more about the side effects of Nucala and what you can do to avoid them.

How do I take Nucala?

The medication is injected under your skin (subcutaneous injection) once every 4 weeks. The injection can be given by your doctor or another healthcare professional. It can also be administered at home using a prefilled syringe or prefilled autoinjector, either by yourself or by a caregiver. Nucala reduces how much inflammation you have in your body, easing your symptoms and making flare-ups of more severe symptoms less likely.

How does Nucala work?

The active ingredient in Nucala is called mepolizumab. Mepolizumab is a type of medicine called a humanized monoclonal antibody that has been designed to target the substance in your body that triggers inflammation.

Your immune system triggers inflammation in your tissues through a complex process with a number of steps. Mepolizumab works by blocking one of these steps. It attaches to and blocks a signaling molecule released by your white blood cells called interleukin. This stops interleukin from activating the next step in the inflammatory process and reduces how much inflammation you have in your body.

Inflammation in the body is an important part of how asthma develops, and eosinophils are one of the many cells in your body involved in inflammation. Blocking interleukin helps to reduce the production of eosinophils, reduce inflammation and help to treat asthma.

What are the most common side effects of Nucala?

The most common side effects caused by Nucala compared to placebo include:

  • Injection site reactions – pain, itching, a burning feeling, redness, and swelling
  • Urinary tract infections
  • Eczema
  • Headaches
  • Back pain
  • Tiredness

Serious side effects of Nucala

In rarer instances, Nucala can cause more serious side effects. These include:

  • Severe allergic reactions (hypersensitivity) to the medication which can trigger anaphylaxis. This can also cause rashes and hives to break out on your skin, as well as a fall in blood pressure, feeling lightheaded, and dizzy, and swelling of your face, mouth, and throat, breathing problems
  • Red or blistering skin rash and a burning or tingling sensation in your body
  • Reactivation of herpes zoster infection (shingles) if you have previously had the infection

These are not all the possible side effects of Nucala. Call your healthcare provider for medical advice about your side effects. Report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Nucala warnings and precautions

Nucala is not intended to relieve the sudden onset of asthma symptoms. If you experience a sudden onset of symptoms or have a severe asthma attack, use a rescue inhaler or other medicine you have been prescribed for sudden and severe symptoms.

Nucala should not be given to:

  • Adults under 18 years of age to treat eosinophilic granulomatosis with polyangiitis
  • Children under 12 years of age to treat hypereosinophilic syndrome
  • Children under 6 years of age to treat asthma
  • Treat sudden breathing problems

Nucala is not suitable for everyone. Do not take Nucala if you are allergic to the active ingredient mepolizumab or any of the other ingredients in Nucala.

Talk to your doctor about your medical conditions before taking Nucala if you:

  • Are taking any medications that contain steroids or corticosteroids for your asthma
  • Have a parasitic infection (roundworm or tapeworm)
  • Are over 65 years of age
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk

Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements. You are also advised to read the complete drug information provided to you with your medication.

Does Nucala cause weight gain?

Weight gain is not a side effect of Nucala that has been reported during clinical trials.

Does Nucala weaken the immune system?

Nucala reduces the number of eosinophils, a type of white blood cells in the body. White blood cells normally help the body fight infections, but a reduction in their number can increase the risk of developing infections.

How long do Nucala side effects last?

Nucala is injected every 4 weeks. In this regard you should expect any side effects of Nucala to last at least 4 weeks.

What are the long-term side effects of Nucala?

Patients using Nucala long-term developed bronchitis, lower respiratory tract infections, dyspnea, nasal congestion, pharyngitis, nasopharyngitis, and viral respiratory tract infection as long-term side effects.

Does Nucala cause shingles?

Nucala can cause the reactivation of herpes zoster infection (shingles) if you have previously had the infection.

Dioes Nucala cause hair loss?

Hair loss is not a side effect reported in clinical trials of Nucala.

How to avoid Nucala side effects

The best way to avoid side effects is to take Nucala as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Nucala that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Nucala. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Nucala as it can increase your risk of mild, moderate, and severe side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Nucala.

7. Know the signs and symptoms of Nucala side effects

Signs and symptoms of side effects include severe allergic reactions. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Nucala.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Nucala as needed.

Humira alternatives: which other medications can I take?

Humira is the brand name for a human monoclonal antibody, FDA-approved (Food and Drug Administration), and manufactured by Abbvie. It is classed as a Tumor Necrosis Factor (TNF) inhibitor and as a biologic drug. TNF is produced naturally in the body and has been shown to be linked to inflammation.

Humira blocks the effects of TNF preventing inflammation in autoimmune diseases such as ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, Crohn’s Disease, hidradenitis suppurativa, psoriatic arthritis, plaque psoriasis, uveitis, and polyarticular juvenile idiopathic arthritis. Treatment with TNF inhibitors can also suppress the normal action of the immune system and cause serious infections and lymphoma.

Here, we will look at alternative drugs to Humira as potential treatment options for these medical conditions.

What biologic is similar to Humira?

A biologic drug is produced from live organisms or their products for the diagnosis, prevention, or treatment of diseases. Biologic medications include antibodies, vaccines, and interleukins. Biosimilar drugs are biological drugs shown to be as safe, to work as well, and to work in the same way as their reference drug.

Biosimilars include Cimzia (certolizumab pegol), Enbrel (etanercept), Simponi (golimumab), Remicade (infliximab), and Cyltezo, an interchangeable biosimilar available as an alternative to Humira.

Speak to a healthcare professional for medical advice if you are considering changing your therapy from Humira to an alternative. Discontinuing Humira or any other biologic drug abruptly may cause withdrawal effects and your body developing antibodies against the prescription drug.

What is a good substitute for Humira?

Differences in the ability to manage inflammation, the method of administration, how often treatment is administered, and differences in side effects may make one alternative more suitable than another. These may include:

  • Methotrexate is a first line DMARD medication for people suffering from rheumatoid arthritis. Methotreaxate is taken for 3 to 4 months. If results are not seen after this time another DMARD, a biologic agent, or other classe of medication may be added. Methotrexate is much less expensive than biologic medications such as Humira. Methotrexate side effects include gastrointestinal disturbances, such as nausea, and vomiting, liver toxicity and suppression of the immune system. Side effects of methotrexate may be reduced by separating and taking the weekly dose over 2 or 3 doses. Those taking methotrexate will need blood tests every 3 months as a minimum. Methotrexate is not recommended for use in people with kidney problems
  • Remicade is a monoclonal antibody indicated for the treatment of psoriatic arthritis and Crohn’s Disease. Remicade is given as an intravenous infusion and is not self-administered. Remicade side effects include infusion reactions such as fever, and skin reactions. These side effects can occur at an increased risk if treatments are missed. Other common side effects of Remicade are similar to those of Humira. Remicade has the convenience of being given every 4 to 8 weeks
  • Orencia (abatacept) belongs to a class of drugs known as T-cell costimulation modulators which acts as a blocker of T-cells in your immune system. Orencia can be given as a flat-dose subcutaneous injection or as an intravenous infusion based on your body weight. A medical review of all other medications is needed before starting treatment with this medication as Orencia interacts with other medications. Orencia may be added to DMARDs to improve the management of rheumatoid arthritis. It should not be added to a treatment already using a TNF–inhibitor like Humira as it could cause serious infections. Other side effects of Orencia include upper respiratory tract infections, sinus infections, and bronchitis
  • Rituxan (rituximab) is also a monoclonal antibody medication and is classed as a B lymphocyte-depleting agent. B cells are thought to be related to the progression and development of rheumatoid arthritis. Rituxan is not recommended for use in people with severe active infections. Those treated with Rituxan will require prophylactic treatment against infections during treatment and up to 1 year after treatment has stopped. Rituxan is given as an IV infusion under medical supervision. Its side effects include infusion-related reactions, and reactivation of hepatitis B
  • Xeljanz belongs to a class of medications known as Janus Kinase Inhibitors which block the JAK enzyme that normally signals cytokines in the body, causing tissue and joint and inflammation. Xeljanz (tofacitinib) is a tablet that is taken twice each day. Patients lipid profiles, neutrophils and lymphocytes, and liver function are monitored during treatment, and changes to dosing will be based on results to these tests. Xeljanz may cause serious side effects such as sudden cardiovascular death and thrombosis in patients 50 years of age or older who have other cardiovascular risk factors. Other side effects of Xeljanz include upper respiratory tract infection, headaches, diarrhea, skin rash, nausea, vomiting, blood clots, reduced white blood cells, blood clots and risks of other cancers

What works better than Humira?

Alternatives to Humira include methotrexate, Orencia, Remicade, and Rituxan. How well these work for an individual will depend on the individual and the condition they are being treated for. Discuss your treatment plan with your doctor to decide which therapy is best for you.

Is Humira or methotrexate better?

Methotrexate is classed as a DMARD (Disease-modifying antirheumatic drug) and has often been used early in the treatment of rheumatoid arthritis. Methotrexate is normally taken as an oral tablet, while Humira is administered as a subcutaneous injection. Which of these two treatments works best will depend on the individual being treated and the condition they are being treated for. Speak to your doctor to discuss your options.

Natural alternatives to Humira

The key thing to be aware of is that natural supplements such as probiotics, or aloe have not been tested in the same way for safety or effectiveness as conventional drugs and are not approved by the FDA (Food and Drug Administration). Speak to your primary care doctor or healthcare provider for medical advice before using any of these supplements.

Humira generic alternative

Humira is not available in a generic version.

Amgevita vs Humira

Amjevita (adalimumab-atto), an anti-TNF-alpha monoclonal antibody is the first biosimilar product to Humira approved by the FDA. It is used to treat rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Crohn’s disease, ankylosing spondylitis, plaque psoriasis, and ulcerative colitis. Amjevita is however not approved to treat uveitis or hidradenitis suppurativa. Both Amjevita and Humira are administered as a subcutaneous injections.

Jakafi side effects and how to avoid them

Jakafi is a brand-name medication manufactured by Incyte Corporation. It is classified as a kinase inhibitor and used to treat adults with certain bone marrow disorders such as myelofibrosis or polycythemia vera. Jakafi is also used in pediatric patients 12 years of age and older with acute or chronic graft-versus-host disease (GVHD). While Jakafi is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Jakafi include neutropenia and thrombocytopenia. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Jakafi and what you can do to avoid them.

What cancer does Jakafi treat?

Jakafi (ruxolitinib) is classed as a Janus Associated Kinase (JAK) inhibitor approved by the U.S. Food and Drug Administration (FDA) for the treatment of:

  • Intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis in adults
  • Polycythemia vera in adults who do not respond or are intolerant to hydroxyurea
  • Steroid-refractory acute graft-versus-host disease in adult and pediatric patients 12 years of age and older
  • Chronic graft-versus-host disease (GVHD) after other therapies have failed in adult and pediatric patients 12 years of age and older

RELATED: What is Jakafi

Jakafi dosage

Jakafi is available in tablet form, in doses of 5 mg, 10 mg, 15 mg, 20mg, and 25 mg tablets.

You are advised to read the medication guide provided with your medicine for the drug information and prescribing information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: Jakafi Dosage

What are the side effects of Jakafi gvhd?

Some possible side effects of Jakafi in clinical trials include:

  • Anemia (low red blood cell count)
  • Neutropenia (low white blood cell count)
  • Thrombocytopenia (low platelet count)
  • Weight gain
  • Bruising
  • Dizziness
  • Headache
  • Tiredness
  • Diarrhea
  • High cholesterol levels

What other side effects does Jakafi have?

Jakafi can cause some serious side effects including:

  • Low blood cell counts
  • Infections – symptoms may include sore throat, cough, ear pain, sinus pain, pain with passing urine, mouth ulcers
  • Increased risk of certain cancers
  • Increased risk of blood clots
  • Major cardiovascular events including heart attack and stroke
  • Allergic reactions, including anaphylaxis

Contact your doctor for medical advice about any side effects you experience while taking Jakafi. You can report your side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What are the long-term side effects of Jakafi?

  • Jakafi can cause a reduction in platelets, red blood cells, and white blood cell counts. Stop treatment and call your doctor if you develop any unusual bleeding
  • Signs of an infection such as fever, night sweats, nausea, vomiting, or muscle aches. Contact your doctor if you develop a painful skin rash or blisters on the trunk of your body as these may be symptoms of shingles (herpes zoster)
  • Increased risk of non-melanoma skin cancer
  • Increase in cholesterol levels
  • Symptoms of myelofibrosis may become worse after 1 week of stopping Jakafi treatment
  • Increased risk of major cardiovascular events including myocardial infarction, cardiovascular death, and stroke. Call for emergency help if you have symptoms of a heart attack or stroke. Symptoms may include shortness of breath, chest pain, cold sweats, nausea, vomiting, feeling lightheaded, and slurred speech
  • Increased risk of blood clots
  • Increased risk of lymphoma or other cancers, especially in those who smoke, now or in the past

Jakafi drug interactions

When Jakafi is taken with other medicines, they may interact and change how those work. It may also increase the severity and frequency of certain side effects. Make sure your healthcare provider is aware of all the medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some possible drug interactions of Jakafi include:

  • Fluconazole – reduce your Jakafi dosage when taken with fluconazole at doses of less than or equal to 200 mg. Do not take Jakafi if you are taking more than 200mg of fluconazole
  • Jakafi should be reduced, temporarily interrupted, or stopped completely if taken with CYP3A4 inhibitors such as clarithromycin, ketoconazole, or grapefruit juice
  • Jakafi may need to be increased if taken with CYP3A4 inducers such as phenobarbital, phenytoin, or St. John’s Wort

Jakafi warnings & precautions

Don’t take Jakafi if you:

  • Are allergic to the active ingredient ruxolitinib
  • Are allergic to any of the other ingredients in Jakafi
  • Are under 18 years of age and are being treated for myelofibrosis or polycythemia vera
  • Are under 12 years of age and are being treated for acute graft-versus-host disease

Talk to your doctor before taking Jakafi if you:

  • Have an active infection
  • Have or have had hepatitis B
  • Have or have had tuberculosis, or have been in close contact with someone who has tuberculosis
  • Have any liver problems
  • Have kidney problems or are on dialysis
  • Have skin cancer
  • Have high cholesterol or triglycerides blood levels
  • Are pregnant or planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Jakafi, to make sure it is safe for you.

What are the side effects of stopping Jakafi?

Your condition may worsen if treatment with Jakfai is suddenly stopped. You may develop symptoms such as fever, unusual bleeding or bruising, trouble breathing, and dizziness. Your doctor may reduce your treatment slowly to prevent these side effects from occurring. You are advised to consult your healthcare provider for medical advice before stopping treatment with Jakafi and report any signs or symptoms of worsening side effects immediately.

Can Jakafi cause liver damage?

Jakafi may cause liver damage. Your healthcare provider will monitor you closely with blood tests during treatment with Jakafi.

What should you do in case of liver damage?

Be aware of the signs and symptoms of liver damage. This may include a loss of appetite, nausea, vomiting, and upper right-sided stomach pain. Speak to your healthcare provider for medical advice if you experience any of these side effects.

Does Jakafi cause memory problems?

Jakfai may cause side effects such as changes in your mood or behavior, difficulty thinking, confusion, memory loss, and changes in speech, vision, or walking. Contact your doctor right away if you experience any of these very serious side effects.

Is Jakafi chemotherapy?

Jakafi is not classed as chemotherapy. It is a treatment targeted at the production of blood cells.

How long can you take Jakafi?

Jakafi is for long-term treatment and you may take it for up to 6 months. If improvements are not seen after 6 months your doctor may decide to stop treating you with Jakafi.

What is severe neutropenia?

Severe neutropenia is a blood condition where you have very low white blood cells, known as neutrophils, in your blood. Neutrophils normally help to fight bacterial infections by engulfing and killing them. This is known as phagocytosis. Symptoms of severe neutropenia include fever, mouth ulcers, and inflammation of the sinuses, throat, and ears. Those with low levels of neutrophils may catch bacterial infections more easily which may be life-threatening.

How to avoid Jakafi side effects

The best way to avoid side effects is to take Jakafi as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Jakafi that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Jakafi. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Limit your alcohol intake while taking Jakafi as excessive consumption of alcohol could make the side effects of Jakafi worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Jakafi.

7. Know the signs and symptoms of Jakafi side effects

Signs and symptoms of side effects include headaches, tiredness, and dizziness. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Jakafi may cause weight gain., with some patients reporting an increase of 5 to 10% in body weight. If you experience this side effect while taking Jakafi, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Jakafi.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Jakafi as needed.

Cabenuva side effects and how to avoid them

Cabenuva is the brand name for an FDA-approved HIV treatment manufactured by ViiV Healthcare. It is a combination of rilpivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), and cabotegravir, a human immunodeficiency virus type-1 integrase strand transfer inhibitor (INSTI). It is used to treat patients 18 years of age and older with HIV-1 infection as a replacement for the current antiretroviral treatment in patients who are suppressed on an antiretroviral with no past history of failure of treatment and without resistance to rilpivirine or cabotegravir. While Cabenuva is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Cabenuva include injection site reactions and fatigue. Less common, but more serious side effects, can include depression and mood changes.

Learn more about the side effects of Cabenuva and what you can do to avoid them.

Cabenuva dosage

Cabenuva is available as an intramuscular injection kit that containing rilpivirine extended-release (long-acting) injectable suspension and cabotegravir extended-release injectable suspension in separate single-dose vials. It is available in the following doses:

  • Cabenuva 400 mg/600 mg containing 400 mg/2 mL cabotegravir, and 600 mg/2 mL rilpivirine
  • Cabenuva 600 mg/900 mg containing 600 mg/3 mL cabotegravir, and 900 mg/3 mL rilpivirine

How effective is Cabenuva?

Results show that after almost 1 year of treatment, around 92% of people using Cabenuva maintained an undetectable viral load compared to around 95% of people who carried on using their oral treatment. Cabenuva is considered a safe and well-tolerated treatment option.

What are the possible side effects of Cabenuva?

The most common possible side effects of Cabenuva include:

  • Injection site reactions
  • Fever
  • Tiredness, headache
  • Muscle or bone pain
  • Nausea
  • Problems sleeping
  • Feeling dizzy, lightheadedness
  • Rash

In rare instances, Cabenuva can cause more serious side effects.  These can include:

  • Allergic reactions – symptoms include fever, tiredness, muscle or joint pain, sores in the mouth, and swelling of the face, lips, mouth, or tongue
  • Post-injection reactions include trouble breathing, stomach cramping, sweating, numbing of the mouth, anxiety, feeling warm, feeling light-headed, or faint, and changes in blood pressure
  • Liver problems – those with hepatitis B may have changes in liver test results. Liver problems are also been seen in patients without any previous history of problems with their livers or any other risk factors. Contact your doctor immediately if you notice yellowing of the skin or your eyes, darker urine, lighter-colored stools, nausea, loss of appetite, vomiting, or pain and discomfort in the stomach area on the upper right side region
  • Mood changes, depression, anxiety, suicidal thoughts, or thoughts of self-harm

Your doctor will assess the benefits of using Cabenuva against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions to Cabenuva to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

How long do Cabenuva side effects last?

Cabenuva is a long-acting HIV medication that can work for up to 2 months, depending on your treatment plan. It has a half-life of 5 to 11 weeks (half-life is the time it takes for half of the drug to leave your system) but cabotegravir may remain in your body for up to 12 months after your last injection.

Injection-site reactions tend to be mild to moderate and resolve within 3 days, however other more serious side effects may take longer. Speak to your caregiver for medical advice if you are concerned about any of your side effects.

Cabenuva drug interactions

Cabenuva can interact with other medications including:

  • Dexamethasone (in more than 1 dose)
  • Methadone
  • St. John’s wort
  • Antibiotics – azithromycin, clarithromycin, erythromycin, rifabutin, rifampin, rifapentine
  • Seizure medicine – carbamazepine, oxcarbazepine, phenobarbital, phenytoin.

Before taking Cabenuva, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Cabenuva warnings & precautions

You should not use Cabenuva if you:

  • Are allergic to the active ingredients in the Cabenuva injection kit
  • Have previously had an allergic reaction to cabotegravir and/or rilpivirine
  • Are coadministered with drugs where significant decreases in cabotegravir
    and/or rilpivirine plasma concentrations may occur, which may result in
    loss of virologic response

Talk to your doctor before using Cabenuva if you:

  • Are taking any of the medications that could interact with Cabenuva
  • Have had an allergic reaction or a skin rash to drugs containing cabotegravir or rilpivirine in the past
  • Have liver problems, or hepatitis B infection now or in the past
  • Have mental health problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed. It is unknown if Cabenuva passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Cabenuva, to make sure it is safe for you.

Does Cabenuva cause weight gain?

Weight gain is a side effect of Cabenuva. On average, those who receive this drug gain around 2 to 3 pounds. Weight gain is not significant but if you are concerned talk to your doctor for medical advice.

How much does Cabenuva cost per month?

As a guide, Cabenuva intramuscular suspension, extended-release (200 mg-300 mg/mL) will typically cost around $4,150 for a supply of 4 milliliters.

Who should get Cabenuva?

Cabenuva is indicated for the treatment of HIV in individuals 12 years of age or older weighing a minimum of 77 pounds.

What is the best time to take Cabenuva?

Before using Cabenuva, you will have to take one Vocabria tablet and one Edurant tablet once a day for 28 days to assess your tolerability to these medicines.

The recommended dosing schedule is to initiate injections of Cabenuva (600 mg of cabotegravir and 900 mg of rilpivirine) on the last day of the oral lead-in and continue with injections of Cabenuva (400 mg of cabotegravir and 600 mg of rilpivirine) as monthly injections thereafter. A healthcare provider will inject Cabenuva as 2 injections (cabotegravir and rilpivirine), one into each side of your buttocks.

You are advised to read the complete medication guide provided with this medicine for the full drug information and patient information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What can happen with Cabenuva?

Cabenuva can cause common side effects such as injection site reactions (pain, tenderness, hardened mass or lump, swelling, redness, itching, bruising, and warmth), fever, fatigue, headaches, sleep problems, dizziness, and rashes. It can also cause more serious side effects such as allergic reactions and liver problems. Talk to your doctor if you have concerns about taking Cabenuva.

How to avoid Cabenuva side effects

The best way to avoid side effects is to take Cabenuva as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Cabenuva that has been recommended by your doctor. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Cabenuva. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

There are no known interactions between alcohol and Cabenuva, however you should limit your alcohol consumption as excessive intake of alcohol could make the side effects of Cabenuva worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Cabenuva.

7. Know the signs and symptoms of Cabenuva side effects

Signs and symptoms of side effects include liver problems and allergic reactions. If you experience any of these side effects speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Cabenuva.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Cabenuva as needed.

Metformin alternatives: which other diabetes medications can I take?

Metformin is approved by the FDA as a first-line treatment used as part of a treatment plan for diabetes management in people with Type 2 diabetes mellitus. Metformin can be used alone or in combination with other medications. It is also used for the prevention of prediabetes. Diabetic patients are more likely to suffer from other medical conditions like high cholesterol, heart disease, and high blood pressure.

Metformin may also be used for the treatment of polycystic ovary syndrome (PCOS), a condition that affects ovulation and may increase androgen production. Metformin is used in these patients to treat the associated insulin resistance. PCOS increases the risk of developing obesity, depression, infertility, and type 2 diabetes. Metformin has been used to help women with PCOS reduce waist size and help with weight loss. Metformin can also be used for the treatment of metabolic syndrome but is not recommended for the treatment of type 1 diabetes.

Here we will take a look at what metformin is, its benefits and side effects, and the alternatives available.

What are the benefits of metformin?

Metformin reduces blood glucose levels by reducing the production of glucose by the liver, reducing the absorption of glucose in the intestine, and increasing glucose used by adipose tissue and skeletal muscle. Metformin is generally safe and does not tend to cause very low blood sugar or hypoglycemia. Other advantages of metformin include its ability to cause a modest reduction in body weight, and the ease with which it may be used in combination with other medications for blood glucose control.

What are the possible side effects of metformin?

Metformin may not be suitable as a treatment option for everyone. Those who have previously had an allergic reaction of any kind to metformin and any other biguanide should avoid using it. Also, those suffering from severe renal impairment should avoid using metformin, and some patients may not be able to manage some of the gastrointestinal side effects causing them to become non-compliant with this medication. The extended-release form of metformin could help to reduce the undesirable side effects, but not enough to be able to use metformin on a regular basis.

The most common side effects of metformin in clinical trials include:

More serious side effects of metformin include:

  • Unusual muscle pain
  • Problems breathing
  • Dizziness, feeling faint
  • Feeling tired
  • Stomach pain
  • Vomiting
  • Slow or irregular heart rate
  • Lactic acidosis – symptoms include unusual muscle pain, difficulty breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired

What are other treatments for diabetes?

Metformin may not be suitable for all patients due to its side effects, or you may not have an adequate response to your metformin treatment. Luckily, there are many other treatments available for the treatment of Type 2 diabetes. These include:

  • Precose (acarbose) an alpha-glucosidase inhibitor. Precose blocks the formations of glucose and fructose from sucrose in the small intestine, and also helps to delay the absorption and digestion of carbohydrate. Precose is most effective when you consume a diet that is high in carbohydrates. Precose should be taken when starting your meal. Precose is available as a tablet in doses of 25mg, 50mg, and 100mg
  • Januvia (sitagliptin), Tradjenta (linagliptin), Onglyza (saxagliptin) – These are all classed as dipeptidyl peptidase 4 inhibitors (DPP-4 inhibitors). The hormone, glucagon-like peptide 1 (GLP-1) in the gastrointestinal tract facilitates the release of insulin. DPP-4 inhibitors will slow the breakdown of GLP-1 (which would otherwise breakdown quickly) enabling better control of glucose by allowing GLP-1 to act for longer. These drugs have a low risk of causing hypoglycemia. These drugs are taken as oral tablets once daily. They are each available in a range of strengths
  • Victoza (liraglutide), Ozempic (semaglutide), Trulicity (dulaglutide), Bydureon Bcise (exenatide), and Tanzeum (albiglutide) are classed as glucagon-like peptide-1 receptor agonists (GLP-1 RAs). These attach to the GLP-1 receptors to simulate GLP-1 in the gut and promote the release of insulin dependent on the presence of glucose. This class of medication slows gastric emptying and reduces your appetite by stopping a rapid increase in your blood glucose levels after a meal. GLP-1 RAs will help to reduce cardiovascular issues including heart failures, heart attacks, and stroke. GLP-1 RAs are administered as an injection and are available in a range of doses. Victoza injection is used once each day. Ozempic,, Bydureon Bcise, and Trulicity are also given as an injection but only once weekly. Doses of these medications are tirated upwards gradually so as to reduce gastrointestinal side effects such as nausea and diaarhea
  • Glucotrol XL (glipizide), Amaryl (glimepiride), and Micronase (glyburide) are classed as sulfonylureas. This class of drug stimulates beta-cells in the pancreas to release insulin. Prolonged use of sulfonylureas will also cause the liver to produce less glucose. Sulfonylureas are more likely to cause hypoglycemia than other treatments. These are typically available as oral medications in a variety of doses. Treament normally starts at low doses before breakfast, gradually increased to a higher dose, taken twice each day
  • Actos (pioglitazone), Avandia (rosiglitazone) are classed as thiazolidinediones. These attach to receptors in fat cells promoting them to mature and promoting fat to be deposited into peripheral tissues. Insulin sensitivity is also increased by decreasing fat complexes. Weight gain and an increase in fat mass is a common side effect. Thiazolidines are available orally, and taken once or twice each day

What are other alternatives to metformin?

Jardiance (empagliflozin), Invokana (canagliflozin), Farxiga (dapagliflozin) are classed as sodium glucose co-transporter 2 inhibitors (SGLT2). These are used in combination with diet and exercise to help control your blood sugar levels. These will help to remove excess glucose from your body in your urine.

Natural alternatives to metformin

Recommendations for the treatment of diabetics must include lifestyle and diet changes.  As well, the American Diabetes Association suggests:

  • A weight loss goal of 5%
  • Foods in your diet containing unsaturated fats like olive oil and fish
  • Reducing your consumption of saturated fats such as butter and bee
  • Reducing carbohydrate intake
  • Exercise

There are a number of products promoted as natural alternatives to medications such as metformin. These include products such as glucocil, berberine, and insulin. The key thing to be aware of is that these natural supplements have not been tested in the same way for safety or effectiveness as conventional drugs and are not approved by the FDA (Food and Drug Administration). Speak to your primary care professional or healthcare provider for medical advice before using any of these supplements.

Alternatives to metformin for PCOS

PCOS stands for Polycystic ovary syndrome, a condition where a woman may not be able to ovulate, have high androgen levels, or may have small cysts on her ovaries. Symptoms of PCOS may include missed or irregular menstrual periods, infertility, acne, excess hair growth, or weight gain. Insulin-sensitizing drugs are used to treat most women because they have a positive effect on insulin resistance, irregular menstrual periods, obesity, anovulation, and hirsutism.

Your healthcare provider might recommend:

  • Combination birth control pills containing estrogen and progestin. Controlling your hormone levels can reduce your risk for endometrial cancer, irregular bleeding, acne, and excess hair growth
  • Taking progestin can regulate periods and protect you from endometrial cancer
  • Clomiphene, an oral anti-estrogen taken at the start of your menstrual cycle
  • Letrozole (Femara) to stimulate the ovaries
  • Gonadotropins

Over-the-counter metformin alternatives

As stated previously, there are a number of products promoted as natural alternatives to medications such as metformin. These include products such as berberine, glucocil, and insulin. The key thing to be aware of is that these natural supplements have not been tested in the same way for safety or effectiveness as conventional drugs and are not approved by the FDA (Food and Drug Administration) for the treatment of Type 2 diabetes. Speak to your primary care doctor or healthcare provider for medical advice before using any of these supplements.

What alternatives are there to metformin due to diarrhea?

Alternatives to metformin for the treatment of Type 2 diabetes, that may have a reduced risk of causing diarreah include Prandin, Invokana, Jardiance, and Actos. This list is not exhaustive and other diabetes treatments may also be suitable. It is important to remember that as individuals we are all unique, and not all treatments will cause the same side effects to the same extent with everyone. Always speak to your healthcare provider to discuss which treatment is the best for you.

Is there a better drug for type 2 diabetes than metformin?

Insulin is still the most effective treatment available to reduce blood glucose levels, especially in comparison to oral medicines for type 2.

What is the safest diabetic medication for type 2 diabetes?

Metformin is considered to be the safest medication for Type 2 diabetes. Metformin has been used for many years, is safe and effective. Metformin is recommended as a first-line treatment for type 2 diabetes.

Switching from metformin to an alternative

Speak to your doctor or a healthcare professional if you are considering switching from metformin to an alternative diabetes drugs. Do not stop taking metformin without medical advice from your prescriber. Your doctor will discuss your options that are based on your blood tests and physical state. Suddenly stopping metformin could cause your blood sugar levels to increase rapidly and lead to hyperglycemia (high blood sugar).

You may need to switch to an alternative treatment from metformin if you have ongoing gastrointestinal side effects or kidney disease. Consider if you are prepared to inject meds, the side effects you may experience from other treatments, and how well your blood sugar levels are controlled currently. New treatments will require dose adjustments. Also, be aware that it could take some time to determine which treatment plan is right for you.

Symbicort alternatives: which other medications can I take?

Symbicort is the brand name for an FDA (Food and Drug Administration)-approved prescription drug containing 2 active ingredients, budesonide, an inhaled corticosteroid (ICS), and formoterol fumarate dihydrate, a long-acting beta-agonist (LABA) bronchodilator. Symbicort is indicated for asthma control and prevention in adults and children aged 5 and older. Symbicort is manufactured by AstraZeneca and has FDA approval for the treatment of adults with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

Symbicort reduces inflammation and opens the airways in your lungs, helping to reduce breathing problems. Symbicort is not a short-acting, rescue inhaler and should not be used to treat an acute asthma attack or COPD exacerbation. Here, we will take a look at what Symbicort is, how to use it, and the alternatives to Symbicort available on the market.

Symbicort dosage

Symbicort is available as a metered-dose inhaler in the following doses: 80 mcg/4.5 mcg per actuation, and 160 mcg/4.5 mcg per actuation.

Symbicort comes as a dry powder that is inhaled using an inhaler device called a Turbohaler. You usually take the medicine once a day to prevent symptoms from occurring. It can be taken as a preventative measure before an activity that causes you breathing problems.

Symbicort is a maintenance treatment and not a rescue treatment for asthma attacks or bronchospasm. Use only fast-acting aerosol inhalation medicine for an asthma attack such as albuterol. Seek medical attention if your breathing problems get worse, or if you think your medications are not working.

Rinse your mouth with water after each use of your Symbicort inhaler. This will reduce the chances of developing sore throats or oral thrush. If you miss a dose, skip the missed dose and take your next dose at the normally scheduled time. Do not double your doses.

Store your Symbicort Turbohaler at room temperature in an upright position, with the mouthpiece down. Keep away from heat or an open flame. Discard the canister once the counter reads 0 (zero), or if you have been using this particular Turbohaler for longer than 3 months.

Read the medication guide provided with this medicine for the full drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: What is Symbicort?, Symbicort dosage

How to take Symbicort

Symbicort comes in a metered-dose inhaler that needs to be primed before taking your first dose. To prime your Symbicort inhaler hold your inhaler in an upright position and shake for five seconds, remove the mouthpiece cover and press down on the top of your inhaler to release one spray. Repeat this process by shaking for another five seconds and releasing a second spray. After releasing two test sprays, your Symbicort inhaler is ready to use.

To take Symbicort, shake the Symbicort inhaler before each use. Remove the cap and check the mouthpiece is clean. Breathe out releasing as much air out of your lungs as possible. Place the upright mouthpiece in front of your mouth, and breathe in deeply through your mouth while pressing down on the top of the canister once. Hold your breath for 5 to 10 seconds, then breathe out slowly. Repeat this process after one to two minutes. Rinse your mouth out with water to prevent oral fungal infections. Do not swallow the water.

What is the best alternative to Symbicort?

Alternative brand-name medications may be more suitable for certain people, due to side effects from using Symbicort, difficulties using the inhaler device, or Symbicort not working as well as required to manage the symptoms of COPD. Alternatives for the treatment of asthma and COPD include:

RELATED: Symbicort vs AdvairTrelegy vs SymbicortBreo Ellipta vs SymbicortDulera vs Symbicort

What are cheaper alternatives to Symbicort?

How much Symbicort will cost will depend on how many Symbicort Turbohalers you buy and the retailer you buy them from. Cheaper alternatives to Symbicort include Advair, Dulera, and Breo. The generic version of Symbicort may be a cheaper option than the brand-name inhaler.

Are there generic alternatives to Symbicort?

The U.S. Food and Drug Administration (FDA) has approved the generic alternative Breyna, (budesonide and formoterol fumarate dihydrate inhalation aerosol) to Symbicort.

RELATED: Generic Symbicort Inhaler approved by FDA for asthma and COPD

What is the difference between Symbicort and Advair?

Symbicort and Advair are both combination inhalers. Symbicort contains the corticosteroid (steroid) budesonide. Advair contains the corticosteroid fluticasone. Symbicort contains the long-acting bronchodilator formoterol. Advair contains the long-acting bronchodilator salmeterol.

Both Symbicort and Advair are used as maintenance treatments for COPD, and they are both used to treat asthma. Symbicort is used in children 6 years of age and older. Advair is used in children 4 years of age and older. Symbicort is used as two inhalations twice each day. Advair is used as one inhalation twice a day. Symbicort is available as an inhalation aerosol. Advair comes as an inhalation aerosol and inhalation powder. Advair HFA is available as a metered-dose inhaler.

RELATED: Symbicort vs Advair

Natural alternatives to Symbicort?

Magnesium and fish oil have been evaluated with and without Vitamin C. Vitamin C and fish oil are thought to have an anti-inflammatory action that may reduce the symptoms of asthma.

Herbal alternatives thought to help improve symptoms of asthma include peppermint, ginger, and rosemary. Speak to your doctor for medical advice before switching to any of these natural alternatives.

What are the side effects of Symbicort?

The most common side effects of Symbicort (budesonide/formoterol) in clinical trials include:

  • Mild sore throat and coughing
  • Throat irritation
  • Thrush (fungal infections)
  • Nasal congestion
  • Inflammation of the sinuses (sinusitis)
  • Upper respiratory tract infections
  • Back pain
  • Headaches
  • Stomach discomfort
  • Trembling and shaking
  • Pneumonia

More serious side effects of Symbicort include

  • Disturbed sleep
  • Dizziness
  • Nausea
  • Unusual tiredness or weakness
  • Muscle cramps
  • Blurred vision
  • Cataracts, or glaucoma
  • Immune system problem (eg, Churg-Strauss syndrome)
  • Increased risk of bone loss (osteoporosis)
  • High blood sugar (hyperglycemia) – symptoms include increased thirst or urination
  • Decreases in blood potassium levels (hypokalemia)
  • Worsening of breathing problems
  • Serious side effects, including chest pain, fast/slow/irregular heartbeat, severe dizziness, fainting, seizures
  • Serious allergic reactions such as hives, difficulty breathing, shortness of breath, swelling of your face, lips, tongue, or throat

If you experience any of these serious side effects, stop taking Symbicort and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to your healthcare provider or the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

RELATED: Symbicort side effects and how to avoid them

Ozempic alternatives: which other diabetes medications can I take?

Ozempic is a prescription drug manufactured by Novo Nordisk Inc. It is used along with diet and exercise in adults to treat type 2 diabetes mellitus. Ozempic is a glucagon-like peptide 1/GLP-1 receptor agonist that helps with glycemic control by helping to lower blood sugar levels. The active ingredient in Ozempic is semaglutide which stimulates insulin secretion and lowers glucagon secretion, depending on your blood glucose level. Ozempic also lowers the risk of stroke, heart attack, or death in people with type 2 diabetes and cardiovascular disease.

Here, we will take a look at what Ozempic is, how to use it, and the alternatives to Ozempic available on the market.

How does Ozempic work?

Ozempic is a glucagon-like peptide 1 (GLP-1) receptor agonist. Glucagon-like peptide-1 (GLP-1) is a hormone that has multiple actions on glucose which is controlled by the GLP-1 receptors. By binding and activating these receptors, Ozempic lowers blood glucose by stimulating insulin secretion from the pancreas and reducing glucagon secretion. When your blood glucose is high, your body will release more insulin and less glucagon. Ozempic also slightly delays the time it takes your food to empty out of your stomach immediately after eating. This can help reduce the rate at which glucose circulates in your bloodstream.

What can you take instead of Ozempic?

  • Bydureon BCise (exenatide extended-release) – improves glycemic control in adults and children 10 years of age and older when used in combination with diet and exercise for type 2 diabetes
  • Byetta (exenatide) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes
  • Trulicity (dulaglutide) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes, and to reduce the risk of cardiovascular events in adults with type 2 diabetes and heart disease
  • Victoza (liraglutide) – Improves glycemic control in adults and children 10 years of age and older when used in combination with diet and exercise for type 2 diabetes, and reduces the risk of cardiovascular events in adults with type 2 diabetes and heart disease
  • Glucophage (metformin) – in combination with diet and exercise to improve glycemic control in adults and children 10 years of age and older with type 2 diabetes
  • Glucophage XR (metformin extended-release) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes
  • Invokana (canagliflozin) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes, reduce the risk of cardiovascular events in adults with type 2 diabetes and heart disease, reduce the risk of end-stage kidney disease in adults with type 2 diabetes and diabetic nephropathy
  • Jardiance (empagliflozin) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes, reduce the risk of cardiovascular death in adults with type 2 diabetes and heart disease, reduce the risk of cardiovascular death or hospitalization in adults with heart failure and reduced ejection fraction
  • Onglyza (saxagliptin) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes
  • Rybelsus (semaglutide) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes
  • Tradjenta (linagliptin) – in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes
  • Compounded Semaglutide
  • Compounded Tirzepatide

What is better, Trulicity or Ozempic?

Ozempic is proven superior to Trulicity in A1C control and reduction and for reducing weight in adults with type 2 diabetes. Ozempic is not approved for weight loss.

Trulicity is a diabetes drug approved for adults with type 2 diabetes with other risk factors for heart disease, such as smoking, high blood pressure, high cholesterol, and obesity.

RELATED: Ozempic vs Trulicity

Which is better, Wegovy vs Ozempic?

These two drugs contain the same active ingredient, but Wegovy contains a higher dose of semaglutide and was manufactured to treat weight reduction and obesity. Ozempic was manufactured to treat type 2 diabetes.

RELATED: Wegovy vs Ozempic

Which is better, Saxenda vs Ozempic?

The main difference between these two is that Ozempic is injected once weekly, and Saxenda must be used daily. Ozempic works for longer and doesn’t need to be used as often.

RELATED: Saxenda vs Ozempic

Is there an oral alternative to Ozempic?

Oral alternatives to Ozempic include:

  • Sulfonylureas such as Amaryl (glimepiride), Glucotrol (glipizide), Micronase (glyburide), Actos (pioglitazone)
  • Dipeptidyl peptidase-4 inhibitors – Nesina (alogliptin)
  • Antihyperglycemics – Prandin (repaglinide), Starlix (nateglinide)
  • Sodium-glucose co-transporter 2 inhibitors (SGLT2) – Steglatro (ertugliflozin)
  • Glucovance (metformin/glyburide)
  • Invokamet (metformin/canagliflozin)
  • Kazano (metformin/alogliptin)
  • Synjardy (metformin/empagliflozin)
  • Xigduo XR (metformin/dapagliflozin)

Are there cheaper alternatives to Ozempic?

How much you pay for Ozempic or an alternative treatment will depend on how much you buy and the retailer you buy it from. The average monthly cost for Ozempic is $730 per month, a pack of 4 Trulicity injectable pens, 0.75 mg/0.5 ml will cost around $2,000, and Wegovy subcutaneous solution (0.25 mg/0.5 mL) usually costs $1,400 for 2 milliliters. How expensive each treatment is will depend on your monthly usage.

Are there natural alternatives to Ozempic?

Over-the-counter drugs, vitamins, or supplements may be an option to help you manage your blood sugar levels. However, there is a possibility of interactions and effects on blood sugar, that may cause your blood sugar to get too high or too low. The American Diabetes Association advises consulting a healthcare provider before taking any supplements.

Changes to your diet and lifestyle may also help manage and control your blood sugar levels. Speak to your doctor or dietitian for medical advice to find out what the best diet plan is for you. Generally, a healthy well-balanced diet with plenty of fruit and vegetables is the way to go. Exercise is a great way to manage your weight and your blood sugar levels too. Remember to get enough sleep, and try to reduce your stress levels too.

Bear in mind, however, that none of these lifestyle changes can replace your medication. Always discuss your options with your healthcare provider, especially if you have any concerns about your medication.

What are the side effects of Ozempic?

The most common side effects of Ozempic include the following:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Constipation
  • Weight loss

Some serious side effects include:

  • Increased risk of thyroid tumors (thyroid cancer)
  • Pancreatitis
  • Diabetic retinopathy complications
  • Hypoglycemia (low blood sugar) when used with insulin secretagogues or insulin
  • Acute kidney injury
  • Gallbladder disease
  • Allergic reactions

Your doctor will assess the benefits of using Ozempic against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Nalfon to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is the best way to take Ozempic?

  • Ozempic is an injectable medication. Use Ozempic injections exactly as your healthcare provider prescribes it. Inject Ozempic under the skin as a subcutaneous injection into your stomach, thigh, or upper arm
  • Use Ozempic at any time of the day on the same day each week. You may change the day of the week you take this medication as long as your last dose was given 2 or more days before
  • If you miss a dose of Ozempic, take the missed dose as soon as you remember if it’s within 5 days of the missed dose. If more than 5 days have passed, skip the missed dose and take your next dose on the regularly scheduled day
  • Take Ozempic with or without food
  • Don’t mix insulin and Ozempic in the same injection. You may inject them both in the same area but not right next to each other
  • Rotate injection sites with each injection
  • Stay on your diet and exercise program while on Ozempic.
  • Discuss how to prevent, recognize and manage low blood sugar (hypoglycemia), and high blood sugar (hyperglycemia) with your healthcare professional
  • Do not share your Ozempic pen with other people to reduce your risk of infection
  • Store this medication in the refrigerator before its first use. After its first use, you can store it at a controlled room temperature or refrigerate it for 56 days. Keep the pen cap on when not in use. Ozempic should be stored away from heat, direct sunlight, and moisture
  • Your doctor may prescribe Ozempic to be used in addition to other diabetes medications, such as metformin or insulin

Other drugs may interact with Ozempic, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. You should read the full prescribing information and the medication guide provided with this medication and tell your healthcare provider about all of your medications including any supplements you are taking.

What is the generic for Ozempic?

Ozempic is the trademark brand name for semaglutide manufactured by Novo Nordisk. A generic version of Ozempic is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Ozempic savings through NiceRx.

Mounjaro weight loss: does it work?

Mounjaro is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist. It is FDA-approved (U.S. Food and Drug Administration) as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Mounjaro has not been studied in clinical trials with patients that have a history of pancreatitis.

What is Mounjaro (tirzepatide)?

Mounjaro (tirzepatide) is an injectable diabetes drug manufactured by Eli Lilly and Company. It is a new medication used along with diet and exercise to reduce blood sugar levels in adults with type 2 diabetes mellitus. Mounjaro is not indicated to treat type 1 diabetes mellitus or as a weight loss drug for the treatment of obesity.

How does Mounjaro work?

Mounjaro is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. GIP and GLP-1 are hormones called incretins that are involved in managing your blood glucose levels. Mounjaro is the first medication in its class that stimulates both GLP-1 and GIP receptors. This leads to increased insulin secretion by your pancreas and increased sensitivity to the released insulin. It also blocks your liver from producing sugar. This combined effect helps to reduce your blood sugar levels.

Can I take Mounjaro for weight loss?

Mounjaro is not approved as yet for weight loss by the FDA. However, Mounjaro does cause weight loss when used with diet and exercise to treat adults with type 2 diabetes.

Is Mounjaro approved for weight loss?

Mounjaro is not approved by the FDA as a weight loss drug but you may lose some weight if you use it in combination with diet and exercise to improve blood sugar for type 2 diabetes mellitus.

How does Mounjaro work for weight loss?

Mounjaro helps to decrease food intake and slow gastric emptying. This is how quickly food passes through your digestive tract. This helps you to feel fuller for longer and reduces your appetite. Studies show this action may occur in the brain.

Mounjaro stimulates glucose-dependent insulinotropic polypeptide (GIP) receptors and glucagon-like peptide-1 receptors. GIP decreases how much food you eat and increases how much energy you use resulting in weight loss. This may give better results when used with a GLP-1 receptor agonist. Weight loss improves how your body responds to insulin released from your pancreas, helping to further lower your blood sugar.

What is the best way to take Mounjaro to lose weight?

Mounjaro is injected under the skin once weekly. You may inject Mounjaro into your abdomen, thigh, or upper arm. Your starting dose is 2.5 mg, increased every 4 weeks by 2.5 mg to a maximum of 15 mg once weekly.

How much weight can I lose on Mounjaro?

Adults using Mounjaro lost 25 lbs over a 52-week period when used with or without other diabetes medications. Higher doses led to increased weight loss, but also caused an increase in gastrointestinal side effects. Mounjaro is not however approved as a weight loss drug at this time.

What are the alternative weight loss medications to Mounjaro?

Alternative glucose-lowering medications for body weight management include Wegovy, Rybelsus, Compounded Semaglutide injection, and Ozempic, all of which contain semaglutide. These medications are long-acting versions of older GLP-1 medications such as Victoza, Saxenda, and Trulicity.

RELATED: Mounjaro vs TresibaMounjaro vs BydureonMounjaro vs WegovyMounjaro vs TrulicityMounjaro vs Ozempic

Which is better for weight loss Ozempic or Mounjaro?

Mounjaro and Ozempic are both indicated along with diet and exercise to decrease high blood sugar in adults with type 2 diabetes. They are both given as once-weekly subcutaneous injections.

In clinical trials comparing Mounjaro to other diabetes treatments, patients taking the highest recommended dose of Mounjaro lowered their HbA1c levels by 0.5% more than Ozempic.

Patients taking Mounjaro also lost more weight than those taking other medications. They also had an average weight loss of 12 pounds more than patients taking Ozempic, 29 pounds more than those on Tresiba (insulin degludec), and 27 pounds more than Toujeo (insulin glargine) patients.

However, the manufacturer of Oxempic reported fewer digestive side effects and a higher overall tolerance when compared to Mounjaro.

There is currently no generic alternative available for either medication. Mounjaro has an average cost of almost $1200 for 1 carton of 2.5mg/0.5ml pens while Ozempic costs approximately $1000 for #1 prefilled pen of 2mg/1.5ml.

How long does it take Mounjaro to start working?

Mounjaro will start working after the first dose but can take up to several months until you see its full benefit. This is usually because your doctor will titrate your dose every 4 weeks until they find the right dose for you.

What is the cost of Mounjaro?

Mounjaro costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Mounjaro will typically cost around $975 for four weeks of treatment.

Compounded Tirzepatide is available through NiceRx. It is the compounded version of Mounjaro.

Understanding your dosage

Mounjaro is available in single-dose prefilled pens in strengths ranging from 2.5mg/0.5ml to 15mg/0.5ml single-dose prefilled pens.

To understand your dosage read the full prescribing information, instructions for use, and medication guide that comes with Mounjaro. Use Mounjaro exactly as your doctor prescribes it to you. Don’t change your dose or stop taking Mounjaro without discussing it with them.

Mounjaro is injected subcutaneously (under the skin) into your stomach, thigh, or upper arm once a week at any time of the day. It can be taken with or without food. You can change the day of the week you administer Mounjaro if the time between the doses is at least 72 hours (3 days). Rotate the injection site each week.

If you miss a dose of Mounjaro, take the missed dose immediately if it is within the first 4 days after missing the dose. If it has been more than 4 days, skip the missed dose and take your next dose on its scheduled day. Do NOT take 2 doses of Mounjaro within 3 days of each other.

You can inject insulin and Mounjaro in the same area of your body, just not right next to each other. Do not mix the medications together in the same injection.

Store Mounjaro in its original carton in the refrigerator between 36⁰F to 46⁰F (2⁰C to 8⁰C). Each single-dose pen can be stored up to 86⁰F (30⁰C) for 21 days. Do not freeze Mounjaro or use it if it has been frozen.

How do injection pens work?

Pens are preloaded with insulin. To use, twist on a new needle, dial your recommended dose, inject your insulin, and discard the used needle into a sharps container.

Potential side effects

The most common side effects of Mounjaro compared to placebo include:

  • Low blood sugar
  • Nausea
  • Diarrhea
  • Injection site reactions
  • Decreased appetite
  • Vomiting
  • Constipation
  • Indigestion
  • Abdominal pain

Mounjaro can cause serious side effects including:

  • Increased risk of thyroid cancer including thyroid c-cell tumors
  • Pancreatitis
  • Acute kidney injury
  • Diabetic retinopathy complications
  • Acute gallbladder disease

Contact your healthcare provider for medical advice about your medical condition or any side effects you experience while taking Mounjaro. You can report your side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Mounjaro side effects and how to avoid them

Foods to avoid with arthritis

Arthritis is the chronic inflammation of joints in your body. Symptoms include joint pain and bone damage. Osteoarthritis is the most common form. Psoriatic arthritis, rheumatoid arthritis, and gout are also inflammatory autoimmune diseases.

Due to the increased risk of other health conditions, people with osteoarthritis will benefit from following a healthy diet as it will help with weight loss. Here, we will take a look at the foods you should avoid and answer some commonly asked questions about arthritis.

12 foods to avoid with arthritis

  • Foods high in salt – processed meat, cheeses, canned soup. High levels of sodium in diets have been linked to an increased risk of rheumatoid arthritis
  • Foods high in sugar – soda, fructose-sweetened drinks, candy, cakes, ice cream, sweets
  • Red meat has been found to worsen the symptoms of rheumatoid arthritis and increases the risk of inflammatory arthritis
  • Processed foods such as fast food, fried food, and breakfast cereals are high in sugar, preservatives, and other inflammatory ingredients which can make your symptoms of arthritis worse. Diets high in processed food will also increase your risk of other health conditions such as obesity and heart disease, affecting your overall health
  • Foods containing gluten such as wheat, rye, and barley. A gluten-free diet may help to reduce symptoms of arthritis. Also, people with celiac disease are more likely to develop rheumatoid arthritis and vice versa. It has also been found that those with a gluten-free vegan diet reduced their symptoms of rheumatoid arthritis and inflammation
  • Alcohol consumption should be restricted or avoided completely as it can make symptoms of arthritis worse. Alcohol has been seen to worsen arthritis affecting the spinal cord, and increase the severity and number of gout attacks. Excessive alcohol consumption is also linked to an increase in the risk of osteoarthritis
  • Foods high in advanced glycation end products (AGEs). AGEs are produced from foods containing sugars, proteins, and fats. Those with inflammatory arthritis have high amounts of AGEs compared to people without arthritis, and the build-up of AGEs in bones and joints may cause inflammation and oxidative stress. Foods high in protein and fat that are fried, grilled, roasted, broiled, or seared contain the highest levels of AGEs. This includes food such as bacon, roast or fried chicken, and pan-fried or grilled steak. Margarine, mayonnaise, and french fries are also high in AGEs. AGEs tend to build up in tissues in the body, especially as we get older, and are also associated with diseases such as diabetes and rheumatoid arthritis. Reducing levels of AGE may help to reduce inflammation. Whole foods such as vegetables, fish, fruits, and legumes may help to reduce AGE levels in your body
  • Diets containing high levels of omega-6 fatty acids but low in omega-3 fats may increase inflammation in the body making the symptoms of rheumatoid arthritis and osteoarthritis worse. Reducing the consumption of corn, safflower, and vegetable oils high in omega-6 fats, and increasing fatty fish high in omega-3-rich may help to improve symptoms
  • Foods containing saturated fat such as butter, and cheese can also increase inflammation in the body and should be limited to 10% of your dietary intake
  • Trans fats should also be limited, because it reduces good cholesterol, and increases bad cholesterol, raising the level of inflammation
  • Nightshades are vegetables that contain a compound known as solanine. Removing these vegetables from your diet may help to improve your symptoms. These vegetables include tomatoes, chili peppers, potatoes, and eggplant
  • Foods high in purines – purine is converted to uric acid in the body. High levels of uric acid in the blood can cause a type of arthritis known as gout. Food high in purines include red meat, alcohol, cured meat such as bacon and ham, and certain seafood, such as scallops and mussels. A low-purine diet with medication may be recommended by a doctor to help prevent the symptoms of gout.

Can diet help arthritis?

What you eat will affect the levels of inflammation in your body. Some foods may cause inflammation while other foods are anti-inflammatory. Anti-inflammatory foods have been shown to reduce the levels of arthritis pain and its progress. Your body weight will also affect your levels of inflammation. Fat cells naturally produce cytokines, which also increase inflammation. By using your diet you can maintain a healthy weight, which will help reduce inflammation and pressure on bones and joints in your body.

Fruits and vegetables

The Arthritis Foundation recommends certain fruits and vegetables that may be of benefit to those with arthritis:

  • Onions, garlic, and leeks – contain an anti-inflammatory compound called quercetin as well as sulfur compounds that reduce cartilage damage
  • Green leafy vegetables – cabbage, broccoli, and spinach containing calcium and antioxidants
  • Orange and red vegetables such as sweet potatoes, squash, and carrots containing carotenoids
  • Citrus fruits, kiwi fruit, and strawberries – foods high in vitamin C helping to protect bone and cartilage

Anti-inflammatory diet

An anti-inflammatory diet can help you avoid symptoms of inflammation. An example of this is the Mediterranean diet. This diet contains foods such as olive oil, whole grains, fruits, and vegetables, lean meats, eggs, fish, nuts, and seeds. This diet also contains moderate amounts of dairy products but with limited amounts of alcohol, red meat, and sugar.

The Mediterranean diet can help to reduce inflammation and pain in those with osteoarthritis and help to protect against the risk of bone fracture. This diet may also help people lose weight as this diet is mostly plant-based. A 2018 study found men who followed this diet had a reduced risk of developing rheumatoid arthritis.

What foods help arthritis pain go away?

Certain foods will make arthritis pain and inflammation worse, while other foods may actually decrease inflammation and help reduce arthritis pain. Foods that may help reduce arthritis pain include:

  • Fatty fish, salmon, sardines, mackerel, and tuna containing omega-3 fatty acids and vitamin D
  • Dark leafy greens such as spinach, broccoli, kale, and collard greens
  • Olive oil
  • Nuts
  • Berries
  • Garlic and onions
  • Green tea

Are bananas good for arthritis?

Bananas are high in potassium and magnesium and can increase bone density. Magnesium may also help to relieve your arthritis symptoms. Bananas have an antioxidant, anti-inflammatory, and antimicrobial activity that helps to reduce inflammation and improve your body’s immune system.

Are eggs good for arthritis?

Eggs contain substances with anti-inflammatory activity. 2 eggs each week is recommended as part of a healthy balanced diet for most adults with arthritis.

What fruit is not good for arthritis?

Citrus fruits are considered by some to cause inflammation due to their acidity and are advised to avoid them.

What foods are bad for arthritis?

Foods known to increase inflammation and aggravate arthritis symptoms include fatty foods, sweets, foods high in carbohydrates, alcohol, advanced glycation end products (AGEs), foods containing gluten, and foods high in additives.

Are tomatoes bad for arthritis?

While there aren’t any studies to support a link between arthritis pain and most nightshades, tomatoes may be an exception. Tomatoes raise levels of uric acid and trigger gout, a type of arthritis that affects the joints in the toes, fingers, wrists, elbows, and knees.

What medication can I take for arthritis?

Medications for arthritis include Humira, Enbrel, Orencia, Rituxan, and Remicade. Speak to your healthcare provider for medical advice about treatments available.

Capsule vs tablet: what’s the difference?

There are two main choices of oral medication available: capsules and tablets.  Capsules and tablets work by delivering a medication or supplement through your digestive tract for a specific medical purpose.

Wondering which one is right for you? Although capsules and tablets work similarly, there are some differences between them. In some circumstances, one form may be more suitable for you.

Learn more about the advantages and disadvantages of tablets and capsules to help you make an informed decision.

What is a tablet?

A tablet is a small, round, solid piece of medication that is taken orally. Tablets are usually made of compressing powder and can come in different shapes and sizes.

Tablets are manufactured by compressing powdered ingredients together to manufacturer a solid tablet that is absorbed in the digestive tract.

There are three main methods for manufacturing tablets: direct compression, dry granulation, and wet granulation:

  1. Direct compression is the simplest and most common method. The ingredients are mixed and then compressed into tablets without adding any liquid binders.
  2. Dry granulation involves mixing the ingredients and then compressing them into a tablet. This method is often used when the ingredients do not flow well or if they are too fine to be directly compressed.
  3. Wet granulation involves mixing the ingredients with a binding agent, such as water, and then compressing them into a tablet. This method is often used when the ingredients do not flow well or if they are too fine to be directly compressed.

In most cases, tablets also contain inactive ingredients or excipients for binding all of the ingredients in the tablet together.

Tablets are primarily manufactured in three shapes: oblong, round, or disc-shaped. Oblong tablets are also referred to as caplets, which are easier to swallow.

Some tablets have a line across the middle of the pill, which makes the tablet easier to break in half.

As well, some tablets are manufactured with a special coating for preventing the medication from breaking down in the stomach,  which helps to ensure that the tablet will only dissolve after it has entered the small intestine.

There are four main types of tablet forms: chewable tablets, orally disintegrating tablets, sublingual tablets, and effervescent tablets.

Chewable tablets

Chewable tablets are intended to be chewed before being swallowed and absorbed rapidly in the stomach, resulting in a quick onset of action. They may come in various flavors.

Orally disintegrating tablets  (ODT)

Manufactured to dissolve rapidly on the tongue without water, going directly into the bloodstream and working the fastest.

Sublingual tablets

Placed under the tongue to dissolve and be rapidly absorbed into the bloodstream.

Effervescent tablets

Dissolved in water to form a solution or suspension and drunk orally. They come in various fruit flavors and may contain antacids or decongestants.

What is a capsule?

Capsules are medications that are enclosed in an outer shell that is absorbed in the digestive tract. The medication in the capsule is absorbed into the bloodstream and is distributed and metabolized similar to medication that is formulated in a tablet.

There are two common types of capsule forms: hard-shelled capsules and soft-gel capsules.

Hard-shelled capsules

Hard-shelled capsules are made of two pieces: the capsule shell, which is made of gelatin, and the cap, which is made of cellulose. The medication is typically in powder form and is placed into the capsule shell. The cap is then placed onto the shell to close it.

Soft-gel capsules

Soft-gel capsules are made of a soft, gelatinous outer shell and contain a liquid form of medication. The outer shell is made of gelatin and glycerin, and the inner portion contains the medication.

What are the key differences between capsules and tablets?

While both capsules and tablets are safe to take, there are various differences between them. Here is a breakdown of the key differences:

Composition

Capsules are typically made of gelatin or vegetarian-friendly alternatives and contain a powder or liquid form of medication.

Tablets are usually made of compressed powder.

Absorption

Capsules offer better protection against stomach acids so the medication is not degraded. Capsules are composed of two parts: an inner suspension and an outer shell. The inner suspension may be in liquid, semisolid, or powdered form while the outer shell is usually made of gelatin. Capsules can have a higher level of bioavailability that results in the medication entering your bloodstream, making capsules slightly more effective than tablets.

Tablets are compressed powders that may contain binders, fillers, disintegrates, and other inactive ingredients.

Taste

Capsules can mask the taste of the medication, while tablets may have a bitter taste. As a result, capsules are less likely to have an unpleasant taste or odor.

Shelf life

Capsules generally have a longer expiration than tablets.

Animal products

Gelatin, which is derived from animal products, is used to make soft-shell capsules, which may not be desirable for vegetarians. Capsules can also be made from vegetarian-friendly alternatives. Tablets do not generally contain gelatin.

Size

Capsules come in a limited variety of sizes. Tablets also come in a variety of sizes, but they can be easily broken in half if needed. As there is a limited amount of space in a capsule, larger formulations are sometimes more practical to be formulated in a tablet as they allow tablet manufacturers to pack more product into a smaller space than with capsules or other delivery systems.

Splitting

Capsules generally cannot be split. Tablets that are scored can be easily split in half.

Chewable

Capsules are not chewable. Tablets can be made into chewable form, but they may not taste as good as capsules.

Unpredictability

Capsules offer an element of unpredictability as the contents may not be evenly distributed. Tablets are generally more predictable as the active ingredient is evenly distributed throughout the tablet.

Irritation

Capsules may irritate the stomach lining and cause nausea. Tablets are less likely to irritate the stomach lining.

Accuracy of prescriptions

Tablets can be split so patients may not follow their prescribed dose. On the other hand, capsules cannot be split so the patient will need to take the entire pill as prescribed by their doctor.

Capsule vs tablet absorption

Capsules offer better protection against stomach acids so the medication is not degraded. Capsules are composed of two parts: an inner suspension and an outer shell. The inner suspension may be in liquid, semisolid, or powdered form while the outer shell is usually made of gelatin. Tablets are compressed powders that may contain binders, fillers, and other inactive ingredients. Consequently, tablets generally have better absorption than capsules.

Difference between capsule and caplet

A capsule is a two-piece enclosure, typically made of gelatin, that contains a powder or liquid form of medication. A caplet is a solid dosage form that resembles a capsule in shape but is usually coated to make it easier to swallow. Capsules are generally not coated and are meant to be swallowed whole. Caplets may be coated with an enteric coating, which protects the medication from being degraded by stomach acids. Capsules are not coated and may irritate the stomach lining.

What are the disadvantages of capsules?

  • Less stable and durable than tablets, and may be susceptible to environmental conditions, specifically humidity.
  • Shorter expiration date than tablets.
  • More expensive to manufacturer than tablets.
  • May contain animal ingredients such as gelatin which aren’t favorable for vegetarians.
  • Lower doses are available as the capsule size cannot accommodate larger formulations.

What are the disadvantages of tablets?

  • May have a bitter taste.
  • More likely to irritate the gastrointestinal tract.
  • Extended-release tablets may not be split so patients may not follow their prescribed dose.
  • Once in the body, they are slower acting than capsules and take longer to work in the body.
  • Unlikely to break down evenly in the system.

What are some tips for swallowing large pills?

Many people can find swallowing large pills uneasy.

Both capsules and tablets may present challenges with swallowing. Tablets are hard and stiff, and some types of tablets could be more challenging to swallow than others. As well, some capsules can be large and difficult to swallow, especially particularly soft gel capsules.

There are some recommended strategies that you can try to make it less challenging to swallow a capsule or tablet.

  • Drink from a bottle that has a narrow opening.
  • Lean forward slightly when swallowing the pill.
  • Add the pill to a food that is semi-liquid, for example, pudding or applesauce.

Tablets vs capsules: which is better?

It depends on your individual circumstances. The best form is the one that is most effective for the person who is taking the medication. While both capsules and tablets have a similar purpose, they have some differences as well.

Tablets come in a various forms and have a longer shelf life than capsules. They also contain higher doses of the active ingredients than capsules can accommodate. Tablets are slower acting than capsules, and in some cases, tablets may disintegrate unevenly in the body.

Capsules are faster acting than tablets, as the majority, if not all, of the drug is absorbed in the body once the capsule is taken. However, capsules generally expire more quickly than tablets, and cost more money.

If you are allergic to certain additives, require a vegan option that excludes capsules as an option for you, or have challenges swallowing large pills, speak with your doctor who will help you identify the best capsules or tablet for your needs.

If you still aren’t sure which one is better for you, speak to your healthcare for medical advice.

Foods to avoid with osteoporosis

Osteoporosis is thought to affect around one in three women and one in five men around the world. As we get older, our bones become more brittle, but a healthy well balanced nutritious diet can help maintain the strength of your bones and muscles. Strong bones need calcium and vitamin D. Calcium helps to strengthen your bones and teeth, while vitamin D will help your body absorb the calcium in your diet.

In this article, we will take a look at what osteoporosis is, what foods you should avoid, the foods you should eat, and other commonly asked questions about how a balanced diet can affect osteoporosis.

What is osteoporosis?

People diagnosed with osteoporosis will have low bone mass and bone tissue, and their bones will become weaker with an increased risk of fractures. Individuals may lose bone density as they age or during menopause, leading to an increased risk of osteoporosis. Your ethnicity will also play a part in the risk of you developing osteoporosis.

What foods should I avoid with osteoporosis?

  • Salt – salt is present in nearly all processed foods, whole grain bread, breakfast cereals, and fast foods. To reduce your salt intake limit food such as ham, deli turkey, hot dogs, reduced-calorie meals, canned soups, pizzas, burgers, and fries. It has been found that postmenopausal women on a high-salt diet lose more of their bone minerals. If you are unable to reduce your salt intake, eat potassium-rich foods, such as tomatoes, bananas, and orange juice. Potassium has been shown to help reduce calcium loss
  • Soda drinks – certain carbonated soft drinks such as cola contain phosphoric acid, which can increase the excretion of calcium in your urine. Also, most soft drinks are low in calcium levels. To prevent osteoporosis drink orange juice that contains calcium and vitamin D, fruit smoothies, or fat-free plain or chocolate milk. Also, heavy alcohol drinking can lead to bone loss. Make sure you limit your alcohol consumption
  • Caffeine – limit yourself to four cups of coffee a day if your level of calcium intake is not high, or if you have other risk factors for osteoporosis. Drink half or full-decaf coffee, iced tea, or hot tea. Tea is actually thought to help improve bone mineral density in older women, whether they add milk to their drinks or not. This may be due to the tea containing plant compounds that help to protect bone
  • Soy products such as tofu, and tempeh are high in bone-building protein, but will also contain compounds that reduce the absorption of calcium. Oxalates in soy bind with calcium making it unavailable to the body. Soy may cause problems with bone strength if your calcium intake is low. Make sure you get plenty of calcium in your diet to avoid this risk

What foods are good for osteoporosis?

Foods good for osteoporosis include:

  • Dairy products – low-fat and non-fat milk, yogurt, and cheese
  • Fish – canned sardines, salmon, mackerel, and tuna
  • Fruits and vegetables – collard greens, turnip greens, dark green leafy vegetables such as kale, okra, Chinese cabbage, dandelion greens, mustard greens, broccoli, spinach, beet greens, artichokes, plantains, potatoes, sweet potatoes, prunes, raisins, tomato products, papaya, oranges, orange juice, bananas, red peppers, green peppers, oranges, grapefruits, strawberries, brussels sprouts, papaya and pineapples
  • Fortified Foods – breakfast foods, soy milk, rice milk, cereals, snacks, and bread

Best calcium foods for osteoporosis

Some people may need to take calcium supplements to treat osteoporosis. Some people may get enough calcium through food sources. The list above is a comprehensive list of foods high in calcium.

Whats foods are good for healthy bones and muscles?

Strong bones require calcium and vitamin D. Calcium strengthens your bones and teeth, and vitamin D will help your body absorb the calcium more effectively.

The recommended amounts of calcium and vitamin D every day for adults up to the age 50 are 1 gram of calcium and 200 International Units (IU) of vitamin D each day. Older adults require 1.2 grams of calcium and 400 to 600 IU of Vitamin D daily. Vitamin D is found in fortified milk, saltwater fish, egg yolks, liver, supplements, and natural sunlight.

Calcium and vitamin D are both available in supplements, and in your diet naturally. Foods containing calcium and vitamin D include:

  • Yogurt
  • Milk
  • Salmon and tuna
  • Spinach
  • Fortified foods

Women are recommended to get around 46 grams of protein daily. Men should get about 56 grams daily. Protein helps to build muscle and muscle will help to burn fat. Foods containing protein include:

  • Lean meats such as steak, chicken, and lean cuts of red meat
  • Fish
  • Greek yogurt – one cup of plain Greek yogurt contains around 24 grams of protein. Adding fresh fruit and nuts will add flavor and keep the calories down
  • Eggs – the yolk contains calcium and protein
  • Nut butter – peanut butter and almond butter are packed full of protein

Is oatmeal good for osteoporosis?

Oats are considered to be the best whole grain to prevent osteoporosis. Combining minerals within oats is great for improving bone mineral density.

What foods make osteoporosis worse?

Ultra-processed foods, foods with added sugar, and high in salt are the worst foods for bone health and may increase your risk of osteoporosis.

Are bananas good for osteoporosis?

Foods high in potassium can help build good bone health. Bananas, tomatoes, papayas, and oranges, are all high in potassium content. Orange juice and raisins are also an option but contain high levels of sugar.

What foods are high sources of calcium?

Foods high in calcium include dairy products, fish (canned sardines, salmon, mackerel, and tuna), fruits and vegetables (such as collard greens, dark green leafy vegetables, okra, broccoli, sweet potatoes, papaya, bananas, and pineapples), and fortified foods (breakfast foods, soy milk, rice milk, cereals, snacks, and bread).

The recommended amounts of calcium and vitamin D every day for adults up to the age 50 are 1 gram of calcium and 200 International Units (IU) of vitamin D each day. Older adults require 1.2 grams of calcium and 400 to 600 IU of Vitamin D daily. Vitamin D is found in fortified milk, saltwater fish, egg yolks, liver, supplements, and natural sunlight.

Meat and other high protein foods

Older adults generally do not consume enough protein, and this may potentially be harmful to their bones, but high protein diets containing meat can be equally as harmful and also cause your body to lose calcium. Red meat in partcular can cause your bones to lose calcium. Limit red meat to twice a week. Also, avoid processed or cured meats.

The recommended daily protein intake is 0.8 grams per 2.2 pounds of body weight for men and women over the age of 19. Protein is available in a number of different food sources such as fish, chicken, fat-free plain yogurt, and eggs.

What foods block calcium absorption?

Foods high in salts (such as processed foods, whole grain bread, breakfast cereals, and fast foods), some soda drinks, caffeine, and soy products (such as tofu, and tempeh) reduce the absorption of calcium. Also, beans (legumes) high in calcium, magnesium, fiber, and other nutrients are also high in phytates. Phytates block your body’s ability to absorb calcium contained in the beans.

How do you stop taking Eliquis safely?

Eliquis is a brand-name medication manufactured by Bristol-Myers Squibb. It is an anticoagulant used to prevent blood clots from forming in the body.

Here we will take a look at what Eliquis is, how you take it, its side effects, drug interactions, precautions, and how to stop taking it safely.

What is Eliquis (apixaban)?

Eliquis is an anticoagulant, a type of drug that stops blood clotting (coagulation). The medication is used to prevent blood clots from forming in people who have:

  • Nonvalvular atrial fibrillation/AFiB (irregular heartbeat not caused by a heart valve problem) and who have other clotting risk factors
  • Had hip or knee replacement surgery

It’s also used to treat deep vein thrombosis (DVT’s) and pulmonary embolism, and to stop blood clots from reoccurring in blood vessels in these places.

Blood clotting is a normal process that happens when you’re injured. If you cut yourself, a clot forms to seal the cut to stop you from losing any more blood. But sometimes blood can clot inside your body where it shouldn’t, and this can cause problems. Clots can block the flow of blood, starving parts of the body of oxygen, and damaging tissues. Depending on where blood clots form, they can cause deep vein thrombosis, heart attacks, and strokes. Sometimes Eliquis is called a blood thinner, as it helps to lower the chances of blood clots forming.

The active ingredient in Eliquis is an anticoagulant called apixaban. As blood clots, it goes through a process of chemical reactions that turn it from a liquid into a thick gel. An enzyme called factor Xa is an important part of this process. Apixaban is a factor Xa inhibitor and attaches to factor Xa to stop it from working, reducing the likelihood of blood clots forming.

Eliquis dosage

Eliquis is available in tablet form, in the following doses: 2.5 mg and 5 mg.

The recommended dose of Eliquis is 5 mg orally twice daily. For elderly patients 80 years of age or older, weighing 60 kg or less, or having serum creatinine equal to or above 1.5 mg/dL, the recommended dose is 2.5 mg orally twice daily.

If you are unable to swallow the tablets whole, you may crush them and mix with water, apple juice, or applesauce and taken orally. Crushed tablets may also be mixed with 60 mL of water and given through a nasogastric tube.

If you take heparin, warfarin, Coumadin, or Jantoven, your doctor will give you instructions about how to switch to apixaban. You do not need to monitor your Vitamin K intake while taking Eliquis. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the normal time.

You are advised to read the prescribing information, and medication guide provided with this medicine for the full drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Common side effects of Eliquis

The most common possible side effects of Eliquis in clinical trials include:

  • Increased bleeding risk – anemia, increased bruising, bloody or brown urine or bloody or tarry stools, bleeding from your anus or vagina, vomiting blood or what appears to look like dark coffee grounds, unusual nosebleeds
  • Headache, dizziness, weakness, pain, swelling, or discomfort in a joint
  • Pinpoint red spots on your skin

Eliquis can cause more serious side effects, including:

  • Major bleeding
  • Joint pain
  • Life-threatening allergic reactions including anaphylactic allergic reactions. This is a medical emergency. Call your doctor right away if you develop a skin rash, itching, trouble breathing, chest pain, difficulty swallowing, or any swelling of your hands, face, or mouth
  • Thrombocytopenia (including platelet count decreases)
  • Hypotension
  • Epistaxis
  • Gastrointestinal hemorrhage (bleeding)
  • Abnormal liver function tests
  • Incision-site hematoma

If you experience any serious side effects, stop taking Eliquis and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Eliquis warnings & precautions

Don’t take Eliquis if you:

  • Are allergic to the active ingredient apixaban
  • Are allergic to any of the other ingredients found in Eliquis
  • Have artificial heart valves
  • Have antiphospholipid syndrome (APS), especially with positive triple antibody testing, and have a history of blood clots
  • Are under 18 years of age
  • Are bleeding excessively
  • Have an organ condition that increases the likelihood of serious internal bleeding, like a stomach ulcer

Talk to your doctor about your medical condition before taking Eliquis if you:

  • Have an increased risk of bleeding, such as a bleeding disorder or very high blood pressure
  • Are over 75 years of age
  • Weigh 60kg or less
  • Have a severe kidney disease or are on dialysis
  • Have a liver problem or a history of liver problems
  • Have antiphospholipid syndrome
  • Are lactose intolerant
  • Need to have surgery or another procedure that can cause bleeding
  • You are pregnant or breastfeeding

You should always check with your doctor or pharmacist before taking any medication, including Eliquis, to make sure it is safe for you.

Other warnings you should know about

  • Eliquis may need to be temporarily stopped a few days before surgery of any sort, including dental procedures
  • Speak to your doctor before you stop using this medicine. There may be a higher risk of stroke if you stop using this medicine suddenly.
  • Grapefruit juice may increase the amount of Eliquis in your body. Talk with your health care provider or pharmacist if grapefruit is part of your diet
  • Eliquis may increase the risk of blood clots in the epidural area or spine. The risk of this occurring increases if an epidural catheter has been previously placed in your back prior to treatment with Eliquis, if NSAIDs or anticoagulants are being taken, if you have previously had spinal punctures in the epidural area or any other issues with your spine, or if you have had surgery in the past on your spine. Symptoms may include a tingling sensation, feeling numb, or muscle weakness, specifically in your feet or legs.

Eliquis drug interactions

Eliquis can interact with other medications. These include:

  • An antifungal medicine
  • Antiviral medicines for HIV/AIDS
  • Nonsteroidal anti-inflammatory drugs
  • Pain medications
  • Medicines for high blood pressure or heart problems
  • Antithrombotics
  • Vitamin K antagonists
  • Antidepressants
  • Medicines to prevent epilepsy or seizures
  • Medicines to treat tuberculosis
  • St John’s Wort

Eliquis can interact with other medications. This can change how Eliquis works and can make side effects more likely. Tell your prescribing physician about all your drugs, including over-the-counter, vitamins and dietary supplements.

Can you stop taking Eliquis cold turkey?

Eliquis does not cause withdrawal symptoms when stopped suddenly. But stopping treatment with Eliquis suddenly may increase the risk of blood clots.

What happens when you stop taking Eliquis?

How fast blood clots in your body will return to what it was before you started taking Eliquis. This is normally within a few days. You may be at a higher risk of a heart attack, stroke, pulmonary embolism, or deep vein thrombosis.

How long does Eliquis stay in your system after stopping?

Eliquis will stay in your system for around 24 hours after you have stopped taking it.

Can stopping Eliquis cause a stroke?

Stopping treatment with Eliquis will increase your risk of a stroke if you were taking it for atrial fibrillation. Speak to your doctor for medical advice if you are considering stopping Eliquis.

How long do you need to stop Eliquis before surgery?

Treatment with Eliquis should be stopped one or two days before surgery or any dental procedure. Speak to your doctor for medical advice if you are thinking about stopping your Eliquis.

Does Eliquis cause depression or anxiety?

Eliquis is not associated with causing anxiety or depression.

How do you switch from Eliquis to aspirin?

Aspirin should not be taken with Eliquis, unless prescribed by a doctor. Speak to your doctor for advice on how to switch from Eliquis to aspirin safely.

How long does it take to stop Eliquis?

The effects of Eliquis on blood clotting begin to reduce within 24 hours of stopping treatment in most people.

What are the side effects of stopping Eliquis?

Eliquis does not cause withdrawal symptoms when stopped. But stopping treatment with Eliquis may increase the risk of blood clots. This is normally within a few days. You may be at a higher risk of a heart attack, stroke, pulmonary embolism, or deep vein thrombosis.

What should you do if you forget to take Eliquis?

If you miss a dose of Eliquis, take it as soon as you remember but if it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

What happens when you suddenly stop taking blood thinners?

Stopping blood thinners suddenly can increase the risk of blood clots.

Can you stop Eliquis for 3 days?

Eliquis can be stopped 2-3 days before surgery

Do you have to stop taking Eliquis if you get pregnant?

Anticoagulant treatments such as Eliquis, Pradaxa, and Xarelto are not recommended during pregnancy. Treatment with Eliquis may cause uterine bleeding.

Do you need to wean off of Eliquis?

No, you do not need to wean of Eliquis as it does not cause withdrawal symptoms if stopped suddenly. Stopping Eliquis treatment may however increase your risk of blood clots.

How do you get help if you’re addicted to Eliquis?

Eliquis is not addictive and does not cause withdrawal symptoms when stopped. Speak to your doctor for medical advice if you are planning to stop taking Eliquis,

Qsymia side effects and how to avoid them

Qsymia is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Vivus, Inc. It is used with a reduced-calorie diet and an increase in physical activity for chronic weight management in adults with a body mass index (BMI) of 30 kg/m2 or more (obese), or 27 kg/m2 or more (overweight) with at least one weight-related comorbidity such as hypertension (high blood pressure), type 2 diabetes mellitus, or dyslipidemia (high cholesterol). While Qsymia is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Qsymia include difficulty sleeping. Less common, but more serious side effects, can include suicidal thoughts or behavior.

Learn more about the side effects of Qsymia and what you can do to avoid them.

What is Qsymia (phentermine and topiramate)?

Qsymia contains phentermine, an appetite suppressant belonging to a class of drugs called sympathomimetic amines, and topiramate, an anticonvulsant. As Qsymia contains phentermine, a Schedule IV drug, it too is controlled under Schedule IV of the Controlled Substances Act. Qsymia is only available under a special program called the Qsymia REMS program.

Qsymia dosage

Qsymia is available in capsule form, in the following doses: phentermine/topiramate extended-release 3.75 mg/23 mg, 7.5 mg/46 mg, 11.25 mg/69 mg, or 15 mg/92 mg.

The recommended dose of Qsymia is 3.75 mg/23 mg daily for 14 days, then increased to 7.5 mg/46 mg daily. Weight loss should be checked after 12 weeks. If a patient has not lost a minimum of 3% of baseline body weight, stop treatment or reduce the dose as it is unlikely the patient will achieve and maintain clinically meaningful weight loss at this dose. If you miss a dose of Qsymia, skip the missed dose and take your next dose at the normal time. Do not double your dose to catch up.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Qsymia side effects

The most common side effects of Qsymia in clinical trials compared to placebo include:

  • Paraesthesia
  • Skin reactions
  • Back pain
  • Dizziness
  • Dysgeusia
  • Trouble sleeping
  • Drowsiness
  • Constipation
  • Dry mouth

In rare instances, Qsymia can cause more serious side effects. These can include:

  • Fetal Toxicity – females of reproductive potential should obtain a negative pregnancy test before treatment and monthly after that, and use effective contraception
  • Increase in heart rate
  • Suicidal thoughts or ideation
  • Acute myopia and secondary angle-closure glaucoma
  • Mood changes and sleep disorders
  • Cognitive impairment
  • Metabolic acidosis – loss of appetite, tiredness, thinking problems, irregular heartbeats
  • Elevated creatinine
  • Decreased sweating and increased body temperature
  • Sudden changes in vision such as decreased vision, blurred vision, eye pain/redness

Your doctor will assess the benefits of using Qsymia against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Qsymia to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Qsymia?

Qsymia may cause serious pulmonary hypertension, and heart valve problems. The risk of this occurring increases with long-term use and if used with other appetite suppressants.

Does Qsymia cause hair loss?

Topiramate, one of the active ingredients in Qsymia has been seen to cause hair loss. This is not a common side effect and has only been reported in 1% to 4% of children.

How much weight do you lose on Qsymia?

Patients lost on average 15 lbs after taking Qsymia for around 3 months. After using Qsymia for around 1 year, patients lost on average 24 lbs.

Do the side effects of Qsymia go away?

Some side effects may disappear on their own during treatment and may not need medical attention. This usually occurs as your body becomes used to Qsymia.

How does Qsymia make you feel?

Side effects of Qsymia may include tingling in your hands and feet, feeling dizzy, a change in taste in your mouth, difficulty sleeping, constipation, and dry mouth. Qsymia may also increase your heart rate.

Qsymia drug interactions

Qsymia can interact with other medications. These include:

  • Birth control pills
  • CNS depressants including alcohol
  • Non-potassium sparing diuretics
  • Valproic acid used to control seizures
  • Carbonic anhydrase inhibitors such as acetazolamide, methazolamide, or zonisamide

This list is not exhaustive and other drugs may interact with Qsymia. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Qsymia warnings & precautions

You should not use Qsymia if you:

  • Are allergic to the active ingredients phentermine or topiramate
  • Have had an allergic reaction to any of the other ingredients in Qsymia
  • Have glaucoma
  • Have thyroid problems (hyperthyroidism)
  • Have taken monoamine oxidase inhibitors (MAOIs) within 14 days
  • Have known hypersensitivity or idiosyncrasy to sympathomimetic amines
  • Are pregnant or are planning to become pregnant – may cause birth defects (cleft lip/cleft palate) or harm an unborn baby. Discuss the use of birth control with your doctor

Talk to your doctor before using Qsymia if you:

  • Are taking any of the medications that could interact with Qsymia
  • Have heart problems, or high blood pressure
  • Have heart disease, have had a heart attack or stroke
  • Have diabetes (weight loss may cause low blood sugar)
  • Have metabolic acidosis
  • Have osteomalacia, osteopenia, or osteoporosis
  • Have kidney disease, kidney stones, or dialysis
  • Have liver disease
  • Have depression, suicidal thoughts, or other mental health problems
  • Suffer from seizures
  • Are breastfeeding or are planning to breastfeed – This medication can pass into your breast milk

Other warnings you should know about

Stopping treatment with Qsymia suddenly can cause seizures. You are advised to speak to your healthcare provider before you stop taking Qsymia.

How to avoid Qsymia side effects

The best way to avoid side effects is to take Qsymia as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Qsymia that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Qsymia. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Qsymia as it can increase your risk of serious side effects, such as central nervous system depression, and an increase in your risk of falls.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Qsymia.

7. Know the signs and symptoms of Qsymia side effects

Signs and symptoms of side effects include difficulty sleeping and drowsiness. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Qsymia.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Qsymia as needed.

Esbriet side effects and how to avoid them

Esbriet is a brand-name medication manufactured by Genentech. It is classified as a transforming growth factor inhibitor and is used for the treatment of idiopathic pulmonary fibrosis (IPF). While Esbriet is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Esbriet include gastrointestinal side effects. Less common, but more serious side effects, can include liver problems.

Learn more about the side effects of Esbriet and what you can do to avoid them.

What is Esbriet used for?

Esbriet contains pirfenidone as the active ingredient and is used for the treatment of idiopathic pulmonary fibrosis (IPF), a lung disease. IPF is a condition where scar tissue is formed deep within the lungs. This scar tissue over time becomes thicker and more rigid making it more difficult for the lungs to work properly and harder for you to breathe. The lack of oxygen caused by this affects how other organs function in your body causing other medical complications. Exactly what causes IPF is not known, but the disease is progressive and can be life-threatening. Esbriet will slow the progression of the disease but will not cure IPF.

Pirfenidone belongs to a class of medications called pyridones. Pirfenidone’s mechanism of action is thought to be through reducing lung scarring, by reducing the production of growth factors and procollagens I and II. (Procollagens are used to produce collagen, a protein that usually adds strength and support to many body tissues). The exact mechanism of action for pirfenidone in treating IPF is not fully understood.

How often should Esbriet be taken?

Esbriet is available as tablets: 267 mg, and 801 mg, and as capsules: 267 mg.

Esbriet is started on a dose of one capsule or tablet a day on the first week of treatment. It is gradually increased weekly by one tablet or capsule a week until you are taking one capsule or tablet three times a day. Esbriet is taken with food.

Temporary dose reduction, interruption, or permanent discontinuation of treatment may be required for the management of adverse reactions. Your doctor will carry out blood tests and liver function tests before and during treatment.

If you forget to take a dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at the usual time.

You are advised to read the medication guide provided with this medicine for the complete drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Esbriet?

The most common side effects of Esbriet in clinical trials (incidence of ≥10%) include:

  • Nausea, vomiting, diarrhea, dyspepsia, heartburn (gastroesophageal reflux disease), indigestion, stomach pain, loss of appetite, weight loss
  • Tiredness, headaches, dizziness
  • Joint pain
  • Skin sensitivity to light, skin rash
  • Upper respiratory tract infection
  • Sinusitis, stuffy nose, sore throat, sneezing
  • Non-cardiac chest pain
  • Insomnia (trouble sleeping)
  • Photosensitivity reactions and sunburn – avoid sunlamps and tanning booths. Use sunscreen or sunblock (SPF 50) and wear protective clothing when going outdoors

Esbriet can cause more serious side effects, including:

  • Severe abdominal pains, vomiting, diarrhea
  • Pain or burning in the throat
  • Liver injury – yellow color to eyes or skin (jaundice), darker stools and dark urine, tiredness, easily bruised

If you experience any of these serious side effects, stop taking Esbriet and seek medical attention immediately. You are encouraged to report adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Esbriet cause shortness of breath?

Esbriet may cause serious allergic reactions. Symptoms may include swelling of the face, lips, or tongue, and difficulty in breathing. Speak to your healthcare provider immediately for medical advice if you have these side effects.

Does Esbriet cause joint pain?

Joint pain is a common side effect of Esbriet.

Esbriet drug interactions

Esbriet can interact with other medications including:

  • Treatment for irregular heartbeats – amiodarone
  • Antibiotic treatment – ciprofloxacin, enoxacin
  • Treatment for cancer – capmatinib, pexidartinib, rucaparib, vemurafenib
  • Antidepressants – fluvoxamine
  • Immunosuppressive medication – leflunomide, teriflunomide
  • Treatment for high cholesterol – lomitapide, mipomersen
  • Treatment for hypertension and chronic angina pectoris – mibefradil
  • Medication for Cushing’s disease – osilodrostat

Before taking Esbriet, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Esbriet warnings & precautions

Don’t take Esbriet if you:

  • Are allergic to the active ingredient pirfenidone
  • Have had an allergic reaction to any of the other ingredients in Esbriet

Talk to your doctor before taking Esbriet if you:

  • Are taking any of the medications that could interact with Esbriet
  • Have liver problems
  • Have kidney disease or are receiving dialysis treatment
  • Smoke
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if Esbriet passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Esbriet, to make sure it is safe for you.

What happens if you stop taking Esbriet?

Do not stop taking Esbriet without speaking to your doctor first. Stopping it suddenly could make your condition worse. If you stop taking Esbriet for more than 14 days, you will need to restart treatment with 1 capsule 3 times a day.

Does Esbriet cause memory loss?

Memory loss is a common side effect in those taking Esbriet. It is more common in males who are over 60 and have been taking Esbriet for between 1 to 6 months.

How long can you take Esbriet?

Esbriet is a long-term treatment. Your doctor will monitor your liver function while you are taking this medication and will decide if and when you need to stop using it.

Can you drink alcohol with Esbriet?

Alcohol is not known to interact with Esbriet and it is safe to consume in small amounts. You are advised to consume no more than the weekly units for men or women.

Which is better Esbriet or Ofev?

Which medication is better will depend on each individual and their condition as well as the side effects they experience. Generally, Ofev has a rating of 8.5 out of 10, compared to Esbriet’s 5.5 out of 10.

What is the duration of treatment with Esbriet?

Esbriet is a long-term treatment. Your doctor will monitor your liver function while you are taking this medication and will decide if and when you need to stop using it. In trials, Esbriet was used for an average of 62 weeks but treatment ranged from 2 to 118 weeks.

How to avoid Esbriet side effects

The best way to avoid side effects is to take Esbriet as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Esbriet that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Esbriet. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience problems with your feet while taking Esbriet.

6. Know the signs and symptoms of Esbriet side effects

Signs and symptoms of side effects include gastrointestinal disturbances. If you experience any of these symptoms speak to your doctor for medical advice.

7. Monitor your weight

Esbriet may cause weight loss. If you experience this side effect while taking Esbriet, get medical advice from your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Esbriet.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Esbriet as needed.

What type of pain medication is safe with Eliquis?

Eliquis is the brand name for an FDA-approved prescription drug manufactured by Bristol-Myers Squibb and Pfizer for adults 18 years and older. Eliquis is used to prevent blood clots from forming in the body.

Sometimes people taking Eliquis will also need to take pain relievers for other conditions, and with there being such a variety of painkillers available it’s not always clear what is safe to take. Here, we’ll take a look at what Eliquis is, and which pain relievers are safe to take with it.

What is Eliquis?

Blood clotting is a complex process that helps prevent excessive bleeding when a blood vessel is injured, but sometimes blood clots can form in your body when they are not needed. This can block the flow of blood and lead to strokes or heart attacks. Eliquis is a factor XA inhibitor that stops your blood from clotting. It is approved:

  • To reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (irregular heartbeat)
  • For the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients who have undergone hip or knee replacement surgery
  • For the prevention of venous thromboembolism (VTE), and for the reduction in the risk of recurrent DVT and PE following initial therapy

What type of pain medication is safe with Eliquis?

Acetaminophen (Tylenol) and natural supplements are safe and can be used for pain relief in combination with Eliquis.

What strong painkillers can I take with blood thinners?

Acetaminophen at its recommended dose is the safest pain killer you can take while taking an anticoagulant.

Which pain reliever is not a blood thinner?

Most pain relievers and anti-inflammatories contain blood-thinning agents and should be avoided. Tylenol (acetaminophen) is not a blood thinner and is a safe alternative.

Eliquis and other blood thinners such as Xarelto (rivaroxaban), Coumadin (warfarin), and clopidogrel are not recommended to be taken with nonsteroidal anti-inflammatory drugs (NSAIDs) or with certain antidepressants that may also be used for pain relief, such as selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs).

NSAIDs in combination with certain antidepressants should be avoided as these can increase the risk of bleeding by changing how platelets function.

What anti-inflammatory can I take with Eliquis?

You are advised to avoid anti-inflammatory drugs when taking Eliquis, due to an increase in the risk of bleeding. This will include prescription drugs and OTC pain relievers, as well as nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen.

Can you take extra strength Tylenol with Eliquis?

Tylenol is safe to take with Eliquis. No known drug interactions are known between Eliquis and Tylenol.

What pain relievers should not be taken with Eliquis?

NSAIDs should be avoided when taking Eliquis. Also, some over-the-counter combination medications should also be avoided due to an increased risk of bleeding. These include Advil Dual Action (acetaminophen/ibuprofen) and Excedrin (acetaminophen/aspirin/caffeine).

Can you take tramadol with Eliquis?

Yes, as no interactions have been found between Eliquis and tramadol.

Can you take Tylenol arthritis with Eliquis?

Tylenol is safe to take as a pain reliever with Eliquis, and there are no known interactions between the two. Tylenol does not act as a blood thinner and will not increase bleeding.

What can I take for arthritis pain while on Eliquis?

NSAIDs and Tylenol are both used to treat arthritis pain, headaches, or muscle pains. Tylenol, unlike NSAIDs, is known to be safe to take as a pain reliever with Eliquis.

Can I take ibuprofen with Eliquis?

You are recommended not to take aspirin or ibuprofen while using apixaban unless your doctor has advised you otherwise. Aspirin and ibuprofen may both increase your risk of bleeding when taken with Eliquis.

What is the best painkiller for people with high blood pressure?

Tylenol is most often the best pain reliever for people suffering from high blood pressure, as it will not increase your blood pressure. Alternatives such as nonsteroidal anti-inflammatory drugs such as ibuprofen or naproxen will increase your blood pressure.

Other medical conditions may also increase the risk of drug interactions with Eliquis. Speak to your doctor for medical advice before you start taking Eliquis.

Eliquis and NSAIDs

What are NSAIDs?

NSAIDs stands for non-steroidal anti-inflammatory drugs. These are medicines used to relieve pain and also to reduce inflammation (swelling), as well as to reduce high temperature. The most commonly used NSAIDs include ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac, celecoxib, mefenamic acid, etoricoxib, indomethacin, and aspirin. Aspirin at higher doses is used for pain relief, at lower doses, it may also be used as an antiplatelet or a blood thinner. NSAIDs are available as prescription drugs or over-the-counter (OTC).

What precautions must I take when combining Eliquis and NSAIDs?

NSAIDs can increase the risk of bleeding when taken with Eliquis. Be sure to speak to your doctor or pharmacist for medical advice before taking any OTC drugs during treatment with Eliquis. They will be able to make sure these meds are safe to be taken with Eliquis.

Eliquis and acetaminophen

Acetaminophen is more commonly known as Tylenol or paracetamol. There are no known interactions between Eliquis and acetaminophen. However, over-the-counter pain relievers may contain a combination of acetaminophen with another class of pain reliever such as an NSAID. Speak to a healthcare professional for medical advice about potential drug interactions with OTC treatments and supplements.

Eliquis and opioids

No drug interactions have been found between Eliquis and opioids. This does not however mean that no interactions may occur. Always consult your healthcare provider for advice about any new medications you are planning to take.

What are some of the side effects of Eliquis?

The most common side effects of Eliquis in clinical trials include:

  • Back pain
  • Bruising
  • Heavy menstrual bleeding
  • Nosebleeds
  • Bleeding gums

In rare instances, Eliquis can cause more serious side effects. These can include:

  • Increased risk of bleeding which can cause serious and life-threatening.
  • Spinal or epidural hematoma (bleeding around your spine)
  • Tarry stools
  • Vomiting blood or your vomit looks like coffee grounds
  • Allergic reaction (hives, chest pain, wheezing, trouble breathing, swelling of your face, lips)

Your doctor will assess the benefits of using Eliquis against your risk of side effects. Make sure to read the U.S. Full Prescribing Information, including the boxed warnings and the medication guide to learn more about this medication. You are encouraged to report negative side effects or adverse reactions to Eliquis to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 

How long does Myrbetriq stay in your system?

Myrbetriq (mirabegron) is the brand name for an FDA (U.S. Food and Drug Administration) approved prescription drug manufactured by Astellas Pharma US, Inc. It is classed as an adrenergic agonist and is used to treat overactive bladder (OAB) in adults. Myrbetriq is available as extended-release tablets and granules. Myrbetriq tablets and Myrbetriq granules are two different products and cannot be substituted on a milligram-per-milligram basis.

Here we will take a closer look at What Myrbetriq is, what it is used for, how it works, its side effects, and other commonly asked questions.

What is Myrbetriq used for?

Myrbetriq (mirabegron) is a beta-3 receptor agonist that is used alone or in combination with solifenacin succinate to relieve the symptoms of overactive bladder such as frequent or urgent urination and urinary incontinence. Myrbetriq is approved by the U.S. Food and Drug Administration (FDA) to treat the following conditions:

  • Overactive bladder (OAB) in adults with symptoms such as urinary incontinence, urgency, and urinary frequency. Myrbetriq can be used alone or along with the antimuscarinic medication Vesicare (solifenacin)
  • Neurogenic detrusor overactivity (NDO) in pediatric patients 3 years of age and older and weighing at least 35 kg

RELATED: What is Myrbetriq

How does Myrbetriq work?

The detrusor muscle in your bladder wall relaxes to let your bladder fill with urine and then contracts to squeeze the bladder and release the urine. With an overactive bladder, the bladder muscle contracts more frequently or uncontrollably. This decreases the amount of urine your bladder can hold and makes you feel like you need to urinate frequently. It can also cause urine leakage (incontinence).

Myrbetriq works by binding to beta-3 receptors on detrusor muscle cells. This causes the muscle to relax and allows more urine to be stored by the bladder. This helps decrease how often you urinate as well as prevents incontinence.

Before taking Myrbetriq

Before starting Myrbetriq, tell your healthcare provider if you have any of the following medical conditions:

  • Liver problems or impairment
  • Kidney problems or impairment
  • Uncontrolled high blood pressure
  • Are pregnant, plan on becoming pregnant, or are breast-feeding

What are Myrbetriq’s side effects?

The most common side effects of Myrbetriq include:

  • Hypertension (high blood pressure)
  • Nasopharyngitis (common cold)
  • Headache
  • Urinary tract infection (UTI)
  • Constipation
  • Dry mouth
  • Tachycardia (fast heart rate)
  • Diarrhea
  • Back pain
  • Fatigue
  • Dizziness

Myrbetriq can cause serious side effects including:

  • Life-threatening allergic reactions including hives, angioedema, and trouble breathing
  • Increased risk of urinary retention if you have a bladder outlet obstruction
  • Atrial fibrillation (AFib)

Contact your healthcare professional for medical advice about any side effects you experience while taking Myrbetriq. You can report your side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RELATED: Myrbetriq side effects and how to avoid themSide effects of Myrbetriq in the elderly

Do Myrbetriq side effects go away?

You will find that most of the side effects will go away within a few days to a couple of weeks of you stopping treatment with Myrebetriq. Your doctor will assess the benefits of using Myrbetriq against your risk of side effects. You are encouraged to report side effects or adverse events of Myrbetriq to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long-term side effects of Myrbetriq?

  • Myrbetriq can cause increases in blood pressure. Patients with hypertension should have their blood pressure periodically monitored. It is not recommended in patients with uncontrolled high blood pressure
  • Increased risk of urinary retention in patients with a bladder outlet obstruction (blockage) and those taking anticholinergic medications such as Vesicare (solifenacin)
  • Angioedema (swelling of the face, lips, throat, or tongue) has been reported with Myrbetriq

Myrbetriq drug interactions

When Myrbetriq is taken with other drugs, it may change the way the other drugs work. The other drugs may also change how Myrbetriq works. They may increase the frequency and severity of side effects as well. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take. Some major drug interactions with Myrbetriq include:

  • Medications metabolized by CYP2D6 including Rythmol (propafenone), Mellaril (thioridazine), Tambocor (flecainide), Norpramin (desipramine), and Lopressor (metoprolol)
  • Lanoxin (digoxin)
  • Coumadin (warfarin)

What is the correct dosage for Myrbetriq?

Myrbetriq is available as an extended-release tablet or oral granules. Myrbetriq tablets and Myrbetriq granules are not interchangeable and cannot be substituted on a milligram-per-milligram basis. Your dose may be adjusted if you have severe kidney or liver impairment.

  • No dose adjustment is needed for patients with mild or moderate renal impairment
  • In adult patients with severe renal impairment (eGFR 15-29ml/min/1.73 m^2 ), the daily dose of Myrbetriq should not exceed 25mg
  • Myrbetriq is not recommended for end-stage renal disease (ESRD) patients or those on dialysis
  • No dose adjustment is needed for patients with mild hepatic impairment (Child-Pugh Class A)
  • In adult patients with moderate hepatic impairment (Child-Pugh Class B), the daily dose of Myrbetriq should not exceed 25mg

RELATED: Myrbetriq Dosage

How long does Myrbetriq stay in your system?

Myrbetriq has a half-life of approximately 50 hours, so it will stay in your bloodstream for around 10.5 days after the last dose.

Do I have to take Myrbetriq every day?

Yes, even if you do not have symptoms. Do not wait until your symptoms of OAB are troublesome.

Can I take Myrbetriq every other day?

No. You must continue to take Myrbetriq once daily, every day.

Does Myrbetriq have withdrawal symptoms?

Myrbetriq does not have withdrawal symptoms.

What happens when you stop taking Myrbetriq?

Symptoms of an overactive bladder may come back or get worse if you stop taking this medication. Speak to your doctor for medical advice if you are considering stopping this medication.

Does Myrbetriq affect sleep?

There have been reports by patients of problems sleeping, confusion, anxiety, and hallucinations when taking Myrbetriq. However, these patients did have pre-existing medical conditions or were already taking other medications that may also cause these symptoms.

Does an overactive bladder ever go away?

No, an overactive bladder will not go away on its own. Without treatment the symptoms of OAB can get worse, bladder muscles can weaken and your pelvic floor tissue can become thinner.

Do you have to take Myrbetriq forever?

Myrbetriq treatment is normally long-term. If treatment becomes a problem with Myrbetriq or you no longer require treatment, speak to your doctor.

Can Myrbetriq be stopped suddenly?

Do not stop taking Myrbetriq suddenly without speaking with your doctor first. Symptoms of an overactive bladder may potentially come back or become worse.

How long does Myrbetriq take to work?

Myrbetriq will begin to work immediately but will take 4 to 8 weeks to reach its full benefits.

How long is the half-life of Myrbetriq?

The half-life is the time it takes for half of this drug to leave your system. The half-life in adults is 50 hours and the half-life in children is 26 to 31 hours.

How long until Myrbetriq is out of your system?

Myrbetriq will stay in your body for around 10 days after the last dose if you are an adult and 6 days if you are a child.

Does Myrbetriq cure cancer?

No. Myrbetriq is not associated with curing or causing cancer.

What is the best time of day to take Myrbetriq?

Take Myrbetriq once a day at the same time each day. It does not matter if you take it in the morning or evening.

Does Myrbetriq cause weight gain?

Myrbetriq can cause urinary retention which can lead to temporary weight gain. However, weight gain or weight loss are not side effects associated with Myrbetriq.

Can you take Myrbetriq while you are pregnant or breastfeeding?

There is no clinical data on the use of Myrbetriq in pregnant women to know if there is a risk for birth defects or miscarriage. There is also no data on whether Myrbetriq is found in breast milk or the effects it may have on the infant. It was found in rat milk during animal studies. You should always discuss the risks and benefits of any medication with your healthcare provider if you are pregnant, plan on becoming pregnant, or are breastfeeding.

How long does it take for Myrbetriq to get into your system?

Myrbetriq will start to work after 3 to 4 hours. It will however take 4 to 8 weeks for you to experience the full benefits of this medication.

How long does it take for the effects of Myrbetriq to wear off?

Myrbetriq will stay in your body for around 10 days after the last dose if you are an adult and 6 days if you are a child.

Myrbetriq alternatives

There are other overactive bladder medications that your healthcare provider can prescribe if Myrbetriq is not the right medication for you. Some alternative FDA-approved treatment options include:

RELATED: Comparing Myrbetriq alternatives: which other medications can I take?

How do I take Myrbetriq?

  • Read the full prescribing information including the boxed warning, drug Information leaflet, and medication guide that comes with Myrbetriq.
  • Take Myrbetriq exactly as your doctor prescribes it to you. Do not change your dose or stop taking Myrbetriq without discussing it with them.
  • Myrbetriq tablets are usually taken once a day. If you are taking Vesicare (solifenacin) with Myrbetriq, you should take them once a day at the same time.
  • You should swallow Myrbetriq tablets whole with water. You should not break, crush, or chew the tablet. Adult patients can take Myrbetriq with or without food. Pediatric patients should take Myrbetriq with food.
  • If you miss a dose of Myrbetriq, take it immediately. If it has been more than 12 hours since taking your last dose of Myrbetriq, skip the missed dose and take the next dose at its regular time.
  • Store Myrbetriq tablets in the original bottle at room temperature between 15°C-30°C (59°F-86°F).

Does Entresto improve ejection fraction?

Entresto (sacubitril/valsartan) is a prescription medication used to reduce the risk of cardiovascular death and hospitalization and improve the quality of life in adult patients with chronic heart failure. It is also used to treat pediatric heart failure patients, 1 year of age and older.

Here we will take a look at what heart failure and normal ejection fraction is, what Entresto is, what it’s used for, how to take it, how it works, its side effects, and some commonly asked questions about it.

What is a normal ejection fraction?

Ejection fraction is a measure of how much blood the left ventricle pumps out of the heart with each contraction. Normal ejection fraction according to the American Heart Association (AHA) is around 50% to 75%. If your left ventricle is not working normally a reduced amount of blood is pumped out of your heart.

If your ejection fraction is 50%, that means that half of the blood in your left ventricle is being pumped out with every contraction. Those suffering with heart failure will have ejection fraction of around 40% or less.

What happens in heart failure?

Heart failure (also known as congestive heart failure) happens when the heart is not able to pump blood around the body as it normally would, and usually occurs when the heart has become weak. This causes fluid to accumalate in the lungs causing symptoms such as difficulty breathing. Fluid build up may also cause swelling in the legs and feet. Heart failure is associated with many other diseases such as diabetes, coronary artery disease, hypertension, heart disease (cardiovascular disease), and aging.

The severity of your heart failure is often based on the New York Heart Association (NYHA) classification:

  • Class I – no symptoms observed
  • Class II – normal daily activities can be carried out without encountering problems but may become tired or out of breath when pushed
  • Class III – difficulty completing daily activities
  • Class IV – shortness of breath even when resting

What is Entresto used for?

Entresto (sacubitril/valsartan) is a prescription angiotensin receptor neprilysin inhibitor (ARNI) manufactured by Novartis Pharmaceuticals. Entresto is the first drug to directly treat patients with heart failure with preserved ejection fraction. It is approved by the U.S. Food and Drug Administration (FDA):

  • To reduce the risk of cardiovascular death and hospitalization for heart failure with reduced ejection fraction (HFrEF) in adult patients with chronic heart failure (New York Heart Association) NYHA Class II-IV). HFrEF is also sometimes known as systolic heart failure. Entresto is more beneficial in patients with below-normal left ventricular ejection fraction (LVEF)
  • For the treatment of symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients 1 year of age and older

How does Entresto work?

Entresto is an angiotensin receptor antagonist containing a combination of sacubitril and valsartan. Sacubitril enhances the natriuretic peptide system by neprilysin inhibition. By blocking the enzyme neprilysin, sacubitril prevents the breakdown of N-terminal pro-B-type natriuretic peptides (NT-proBNP) which helps lower blood pressure. This also causes an accumulation of the protein angiotensin II.

Entresto also blocks the renin-angiotensin-aldosterone system. Valsartan is an angiotensin II receptor blocker (ARB) that prevents angiotensin II from binding and causing vasoconstriction (narrowing of your blood vessels), and cardiac stimulation, among other blood pressure-raising effects. Valsartan is used along with sacubitril because it can block the effects of the accumulated angiotensin II.

This combined effect may help to improve heart function by reducing inflammation, cardiac fibrosis, and reducing cardiac remodeling.

What are the side effects of Entresto?

Some common side effects of sacubitril/valsartan in clinical trials include:

  • Hypotension
  • Hyperkalemia
  • Cough
  • Dizziness
  • Lightheadedness

Some serious side effects of Entresto include:

  • Angioedema
  • Worsening kidney disease or function, especially in those with congestive heart failure (CHF)
  • Angioedema (swelling of your face, lips, tongue, and throat) and hypotension (low blood pressure)
  • Allergic reactions – discontinue Entresto immediately and seek medical advice if you have symptoms such as hives, trouble breathing, or swelling of your face, lips, tongue, or throat
  • Increase in potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your healthcare provider

You can report any side effects you experience to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

How is Entresto used?

  • Take Entresto exactly as your healthcare provider prescribes it
  • Entresto’s usual starting dose is 49 mg/51 mg taken twice a day. Your doctor may start you on a lower starting dose or change your dose during treatment
  • If your child can’t swallow tablets, your pharmacist may be able to prepare Entresto as a liquid suspension at the recommended tablet dosage. Please note the suspension will also contain Ora-Sweet SF and Ora-Plus. Shake the suspension well before each use
  • If you miss a dose of Entresto, take it immediately. If it is close to your next dose, do not take the missed dose. Take the next dose at your regular time
  • If you take too much Entresto, call your healthcare provider right away or go to the nearest emergency room
  • Discontinue Entresto as soon as possible when pregnancy is detected
  • It is not known if Entresto passes into your breast milk. Consult your healthcare provider before breastfeeding
  • Read the prescribing information and the Instructions for Use and Medication Guide, including the Boxed Warning that comes with your Entresto prescription

When did the FDA approve Entresto?

Entresto was first approved by the FDA in 2015 based on the PARADIGM-HF trial. Entresto was shown to reduce the risk of hospitalization or cardiovascular death from worsening symptoms of heart failure by 20% after 2 years of treatment. These results showed an improvement in outcomes compared to patients taking the ACE inhibitor enalapril.

The American College of Cardiology, the Heart Failure Society of America, and the American Heart Association included Entresto in their guidelines as a Class 1 recommendation in 2016, based on the findings of the PARADIGM-HF trial.

How long does it take Entresto to improve heart function?

Entresto reaches steady plasma concentrations in the body in 3 days, but will take 3 months to show improvement in heart function, with maximum benefits seen around 12 months after initiating treatment.

How is ejection fraction of the heart measured?

Ejection fraction is measured using echocardiograms. Sound waves produce images of the blood being pumped through your heart and images of the heart itself.

What is the ejection fraction of a healthy heart?

A healthy heart will have an ejection fraction of about 50% to 75%, according to the American Heart Association. Borderline ejection fraction will be between 40% to 50%.

What is the best treatment for ejection fraction?

There are other medications to treat heart failure that your healthcare professional can prescribe if Entresto is not the right medication for you. Some FDA-approved alternative treatment options include:

  • Beta-blockers such as carvedilol, metoprolol, and bisoprolol can slow your heart rate and reduce high blood pressure
  • Angiotensin-converting enzymes (ACE inhibitors) help blood vessels relax and open
  • ARBs such as valsartan and losartan also cause blood vessels to relax and open
  • Neprilysin inhibitors increase the availability of natriuretic peptides helping to dilate blood vessels

Diuretics will help with some heart failure symptoms, but not necessarily improve your heart’s ejection fraction

Can the ejection fraction of the heart be improved?

Yes, the ejection fraction of the heart can be improved by treating heart failure, which will reduce symptoms of heart failure such as tiredness, and difficulty breathing.

How to improve ejection fraction naturally?

There are certain lifestyle changes you can make which will help improve your ejection fraction naturally. Being more active, eating healthy food , reducing your salt and sugar intake, watching your weight and reducing your stress can all help.

How long does it take for Entresto to improve ejection fraction?

Entresto is seen to improve ejection fraction by 5% in 6 months, with a 30% improvement seen at 12 months of treatment.

How much can ejection fraction improve?

Almost 50% of patients had a 5% increase in left ventricular ejection fraction and around 35% had 10% or more of an increase.

How long does Entresto extend life?

Patients with reduced ejection fraction taking Entresto have an expected extended life expectancy of 1.5 to 2 years compared to patients treated with enalapril.

Can ejection fraction improve after a stent?

Yes. Ejection fraction rates have dramatically reduced in patients undergoing medical procedures with stents fitted. Speak to your healthcare provider for medical advice about stents, what they are, and how they are fitted, and the benefits they have if you have heart failure.

Can ejection fraction improve in 3 months?

Ejection fraction will normally show improvement after 3 to 6 months of treatment with Entresto, with greatest improvement seen up to 12 months after starting treatment.

What drugs increase ejection fraction?

Other drugs are available to treat heart failure if Entresto is not right for you. Alternative treatment options include beta-blockers such as carvedilol, metoprolol, and bisoprolol, ACE inhibitors such enalapril, or ramipril, and ARBs such as valsartan and losartan. Diuretics will also help with some heart failure symptoms, but not necessarily heart ejection fraction.

Can Entresto cure heart failure?

Patients with chronic heart failure, will have reduced hospitalizations and death compared to patients taking other drugs for this condition.

Studies conducted using Entresto demonstrate a significant improvement in clinical outcomes such as LVEF, reduction of NT-proBNP, and left ventricular reverse remodeling.

This non randomized trial to evaluate changes in left ventricular ejection fraction (LVEF) in patients with heart failure and reduced LVEF with sacubitril/valsartan treatment included patients with acute and chronic heart failure. Data was also collected about any changes in the size of the left ventricular chamber, blood pressure, and biomarkers such as N-terminal pro-B-type natriuretic peptide (NT-proBNP), and kidney function based on serum creatinine level.

Does Entresto lower blood pressure?

Entresto (sacubitril/valsartan) is a prescription medication used to reduce the risk of cardiovascular death and hospitalization in adult patients with chronic heart failure. It is also used to treat heart failure in pediatric patients 1 year of age and older.

Here we will take a look at what Entresto is, what it’s used for, how to take it, how it works, its side effects, and some commonly asked questions about it.

What is Entresto used for?

Entresto (sacubitril/valsartan) is a prescription angiotensin receptor neprilysin inhibitor (ARNI) manufactured by Novartis Pharmaceuticals. It is approved by the U.S. Food and Drug Administration (FDA):

  • To reduce the risk of cardiovascular death and hospitalization for heart failure with reduced ejection fraction (HFrEF) in adult patients with chronic heart failure. It is more beneficial in patients with left ventricular ejection fraction (LVEF) that is below normal
  • For the treatment of symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients 1 year of age and older

How to take Entresto

  • Take Entresto exactly as your healthcare provider prescribes it
  • Entresto’s usual starting dose is 49 mg/51 mg taken twice a day. Your doctor may start you on a lower starting dose or change your dose during treatment
  • If your child can’t swallow tablets, your pharmacist may be able to prepare Entresto as a liquid suspension at the recommended tablet dosage. Please note the suspension will also contain Ora-Sweet SF and Ora-Plus. Shake the suspension well before each use
  • If you miss a dose of Entresto, take it immediately. If it is close to your next dose, do not take the missed dose. Take the next dose at your regular time
  • If you take too much Entresto, call your healthcare provider right away or go to the nearest emergency room
  • Discontinue Entresto as soon as possible when pregnancy is detected
  • It is not known if Entresto passes into your breast milk. Consult your healthcare provider before breastfeeding
  • Read the prescribing information and the Instructions for Use and Medication Guide, including the Boxed Warning that comes with your Entresto prescription

What are the side effects of Entresto?

Some common side effects of Entresto in clinical trials can include:

  • Hypotension
  • Hyperkalemia
  • Cough
  • Dizziness
  • Lightheadedness

Some serious side effects of Entresto include:

  • Angioedema
  • Worsening kidney function, especially in those with congestive heart failure (CHF)
  • Angioedema (swelling of your face, lips, tongue, and throat) and hypotension (low blood pressure)
  • Severe allergic reactions – discontinue Entresto immediately and seek medical advice if you have symptoms such as hives, trouble breathing, or swelling of your face, lips, tongue, or throat
  • Increase in potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your healthcare provider

You can report any side effects you experience to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Precautions with Entresto

Entresto is contraindicated if you have any of the following medical conditions:

  • Pregnancy – Entresto may harm or cause death to your unborn baby
  • Hypersensitivity to any of the active ingredients of Entresto
  • History of angioedema related to previous angiotensin-converting enzyme inhibitors (ACE inhibitors) or ARBs
  • Hereditary angioedema
  • Do not take Entresto within 36 hours of ACE inhibitors such as lisinopril or ramipril
  • Concomitant use with Tekturna (aliskiren) in patients with diabetes
  • Severe liver problems or liver disease

How quickly does Entresto lower blood pressure?

Entresto will take 30 minutes to 2 hours to reach peak levels, with steady plasma levels maintained after 3 days. When Entresto actually starts to work will however be different for each individual.

Can Entresto lower your blood pressure too much?

Overdose of Entresto will cause side effects such as hypotension, making you feel very lightheaded, dizzy, or tired.

What medications are similar to Entresto?

There are other medications to treat heart failure that your healthcare professional can prescribe if Entresto is not the right medication for you. Some FDA-approved alternative treatment options include:

  • Beta-blockers such as carvedilol, metoprolol, and bisoprolol can slow your heart rate and reduce high blood pressure
  • ACE inhibitors to help blood vessels relax and open
  • ARBs such as valsartan and losartan also cause blood vessels to relax and open
  • Neprilysin inhibitors increase the availability of natriuretic peptides helping to dilate blood vessels

Diuretics will help with some heart failure symptoms, but not necessarily improve your heart’s ejection fraction

What medications should not be taken with Entresto?

When Entresto is taken with other medications, they may interact and change how they work. It may also increase the severity of certain side effects or make them more likely to occur. Make sure your doctor is aware of all the medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some major drug interactions with Entresto include:

  • Aliskiren – avoid use if you have an eGFR < 60
  • Potassium-sparing diuretics (water pills) – can cause hyperkalemia (high potassium levels)
  • Non-steroidal anti-inflammatory drugs (NSAIDs) – meds such as ibuprofen can increase your risk of kidney problems
  • Lithium – may cause lithium toxicity

Does Entresto improve ejection fraction?

Yes. Improvements in ejection fraction are seen between 6 to 12 months of treatment with Entresto.

How long does Entresto extend life?

Patients with reduced ejection fraction taking Entresto have an expected extended life expectancy of 1.5 to 2 years compared to patients treated with enalapril.

What are the dangers of Entresto?

Entresto may cause side effects, some more serious than others. Side effects may include high blood potassium, low blood pressure, or severe kidney problems. Speak to your doctor for medical advice if you experience any side effects.

Can you take carvedilol and Entresto at the same time?

Yes. Carvedilol is classed as a beta-blocker and is commonly used in combination with Entresto.

Does Entresto lower heart rate?

No. Entresto may cause high potassium levels and cause side effects such as chest pain, irregular heartbeat, increased heart rate, nausea, vomiting, or diarrhea.

How long does it take for Entresto to work?

Entresto reaches steady plasma concentrations in the body in 3 days. When it actually starts to work will be different for each individual.

Will Entresto cause dizziness?

Dizziness is a common side effect of Entresto. Speak to your doctor for medical advice if you have this side effect.

Does Entresto make you tired?

Entresto may make you feel light-headed, or faint, or cause you to feel extreme tiredness. Speak to your healthcare provider for medical advice if you have this side effect.

How long does it take Entresto to work?

Entresto (sacubitril/valsartan) is a prescription medication used to reduce the risk of cardiovascular death and hospitalization in adult patients with chronic heart failure. It is also used to treat heart failure in pediatric patients 1 year of age and older.

Learn more about how long it takes for Entresto to work, what it’s used for, how to take it, its side effects, and some commonly asked questions about it.

What is Entresto?

Entresto (sacubitril/valsartan) is a prescription medication used to reduce the risk of cardiovascular death and hospitalization in adult patients with chronic heart failure. It is also used to treat heart failure in pediatric patients 1 year of age and older.

What is Entresto used for?

Entresto (sacubitril/valsartan) is a prescription angiotensin receptor neprilysin inhibitor (ARNI) manufactured by Novartis Pharmaceuticals. It is approved by the U.S. Food and Drug Administration (FDA):

  • To reduce the risk of cardiovascular death and hospitalization for heart failure with reduced ejection fraction (HFrEF) in adult patients with chronic heart failure. It is more beneficial in patients with left ventricular ejection fraction (LVEF) that is below normal
  • For the treatment of symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients 1 year of age and older

How to take Entresto

  • Take Entresto exactly as your healthcare provider prescribes it
  • Entresto’s usual starting dose is 49 mg/51 mg taken twice a day. Your doctor may start you on a lower starting dose or change your dose during treatment
  • If your child can’t swallow tablets, your pharmacist may be able to prepare Entresto as a liquid suspension at the recommended tablet dosage. Please note the suspension will also contain Ora-Sweet SF and Ora-Plus. Shake the suspension well before each use
  • If you miss a dose of Entresto, take it immediately. If it is close to your next dose, do not take the missed dose. Take the next dose at your regular time
  • If you take too much Entresto, call your healthcare provider right away or go to the nearest emergency room
  • Discontinue Entresto as soon as possible when pregnancy is detected
  • It is not known if Entresto passes into your breast milk. Consult your healthcare provider before breastfeeding
  • Read the prescribing information and the Instructions for Use and Medication Guide, including the Boxed Warning that comes with your Entresto prescription

Storage

  • Store bottles of Entresto oral suspension at room temperature between 68°F to 77°F (20°C to 25°C) for up to 15 days. Do not refrigerate Entresto oral suspension
  • Store Entresto tablets at room temperature between 68°F to 77°F (20°C to 25°C) away from moisture

How does Entresto work?

Entresto is a combination product that contains sacubitril and valsartan. Sacubitril acts as a neprilysin inhibitor. By blocking the enzyme neprilysin, sacubitril prevents the breakdown of natriuretic peptides which helps lower blood pressure. This also causes an accumulation of the protein angiotensin II.

Valsartan is an angiotensin II receptor blocker (ARB) that prevents angiotensin II from binding and causing vasoconstriction (narrowing of your blood vessels), and cardiac stimulation, among other blood pressure-raising effects. Valsartan is used along with sacubitril because it can block the effects of the accumulated angiotensin II.

What are the side effects of Entresto?

Some common side effects of Entresto in clinical trials can include:

  • Hypotension
  • Hyperkalemia
  • Cough
  • Dizziness
  • Lightheadedness

Some serious side effects of Entresto include:

  • Angioedema
  • Worsening kidney disease or function, especially in those with congestive heart failure (CHF)
  • Angioedema (swelling of your face, lips, tongue, and throat) and hypotension (low blood pressure)
  • Allergic reactions – discontinue Entresto immediately and seek medical advice if you have symptoms such as hives, trouble breathing, or swelling of your face, lips, tongue, or throat
  • Increase in potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your healthcare provider

You can report any side effects you experience to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What dosage is recommended for Entresto?

Entresto’s usual starting dose is 49 mg/51 mg taken twice a day. Your doctor may start you on a lower starting dose or change your dose during treatment. Your exact dose will be based on your age, weight, and the condition you are being treated for.

What happens if I take too much Entresto?

Overdose of Entresto will cause side effects such as hypotension, making you feel very lightheaded, dizzy, or tired.

Precautions with Entresto

Entresto is contraindicated if you have any of the following medical conditions:

  • Pregnancy
  • Hypersensitivity to any components of Entresto
  • History of angioedema related to previous angiotensin-converting enzyme inhibitors (ACE inhibitors) or ARBs
  • Hereditary angioedema
  • Do not take Entresto within 36 hours of ACE inhibitors such as lisinopril or ramipril
  • Concomitant use with Tekturna (aliskiren) in patients with diabetes
  • Severe liver disease

What other medications interact with Entresto?

When Entresto is taken with other medications, they may interact and change how they work. It may also increase the severity of certain side effects or make them more likely to occur. Make sure your doctor is aware of all the medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some major drug interactions with Entresto include:

  • Aliskiren – avoid use if you have an eGFR < 60
  • Potassium-sparing diuretics (water pills) – can cause hyperkalemia (high potassium levels)
  • Non-steroidal anti-inflammatory drugs (NSAIDs) – meds such as ibuprofen can increase your risk of kidney problems
  • Lithium – may cause lithium toxicity

What medications are similar to Entresto?

There are other medications to treat heart failure that your healthcare professional can prescribe if Entresto is not the right medication for you. Some FDA-approved alternative treatment options include:

  • Beta-blockers such as carvedilol, metoprolol, and bisoprolol can slow your heart rate and reduce high blood pressure
  • ACE inhibitors to help blood vessels relax and open
  • ARBs such as valsartan and losartan also cause blood vessels to relax and open
  • Neprilysin inhibitors increase the availability of natriuretic peptides helping to dilate blood vessels

Diuretics will help with some heart failure symptoms, but not necessarily improve your heart’s ejection fraction

How can I stay healthy while taking Entresto?

Exercise and a healthy balanced diet are recommended while taking Entresto.

What does the drug cost?

Entresto prices will vary depending on the amount you buy and where you buy it from. As a guide, a pack of 60, 24-26 mg Entresto tablets will cost between $620 and $700.

What time of day should Entresto be taken?

Entresto tablets should be taken with or without food in the morning and evening at the same time each day.

How long does Entresto stay in the body?

The active form of sacubitril is 50% eliminated from your body after about 12 hours. Valsartan is 50% eliminated from your body after about 10 hours of taking the Entresto tablet.

How long does it take Entresto to work?

Entresto reaches steady plasma concentrations in the body in 3 days. When it actually starts to work will however be different for each individual.

Can Entresto reverse heart failure?

Entresto has been shown to reduce the risk of cardiovascular death or hospitalization for heart failure by 20% after more than 2 years.

How long does it take Entresto to improve heart function?

Improvements in heart function are seen after 12 months of treatment with Entresto.

Does Entresto make you feel better?

Less than 40% of patients described feeling better while taking Entresto. Over 50% of patients reported a negative experience while using Entresto.

How long does Entresto extend life?

Patients with reduced ejection fraction taking Entresto have an expected extended life expectancy of 1.5 to 2 years compared to patients treated with enalapril.

How long does it take for Entresto to improve ejection fraction?

Improvements in ejection fraction are seen between 6 to 12 months of treatment with Entresto.

What are the dangers of Entresto?

Entresto may cause side effects, some more serious than others. Side effects may include high blood potassium, low blood pressure, or severe kidney problems. Speak to your doctor for medical advice if you experience any side effects.

Can Entresto be taken once a day?

Entresto is recommended to be taken twice daily.

What happens if you suddenly stop taking Entresto?

Do not suddenly stop taking Entresto unless your doctor tells you to. Stopping treatment may cause your condition to get worse.

Does Entresto make you tired?

Entresto may make you feel light-headed, faint, or cause you to feel extreme tiredness. Speak to your healthcare provider for medical advice if you have this side effect.

Does Entresto cause weight gain?

Entresto does not cause weight gain. If you have rapid weight changes it may be that your heart failure is getting worse. Speak to your doctor if you experience rapid weight gain while taking Entresto.

What foods to avoid with eczema

Eczema (atopic dermatitis) is an inflammatory skin condition most common in young children but also affecting adolescents and adults. What causes eczema in certain individuals is not fully understood, but it is thought to have a genetic link as well as being due to external environmental factors. Symptoms of eczema generally include itchy skin, irritation, itchy rashes, and blisters.

People who suffer from eczema also tend to suffer from food allergies, and your dermatologist may recommend avoiding certain foods. Not everyone will have the same allergies to the same food types so finding out which foods you may have an allergy to is important to reduce your flare-ups of eczema.

In this article, we will take a look at what foods you should avoid and what foods are good to eat if you have eczema, as well as some dietary tips to help you manage your symptoms of eczema.

What foods should you not eat during eczema?

The food you eat may not cause eczema but may make your symptoms of eczema worse, especially if you eat food that you have an allergy to. Foods you should avoid if you have eczema include:

  • Dairy products (such as cow’s milk)
  • Eggs
  • Nuts
  • Foods high in trans fats (such as processed food, and fast food)
  • Foods high in sugar (such as cakes, sweets, and sodas) can cause sudden increases in your insulin and cause inflammation

Foods to avoid with eczema in toddlers

The most common foods to be avoided in children with eczema are eggs, milk, and peanuts. These foods also commonly cause allergies in children. Allergies can also occur in other foods such as fish, shellfish, soya, strawberries, and other fruits.

Foods to avoid with eczema in adults

Flavonoid-containing foods are classed as anti-inflammatory foods and are actually recommended in diets with anti-inflammatory properties. However, not all foods will be suitable for everyone and certain flavonoid-containing foods may actually make the symptoms of eczema worse in adults. These include tomatoes, red peppers, berries, and citrus fruits.

Foods to avoid with eczema and psoriasis

Foods often mentioned when talking about psoriasis flare-ups include alcohol, processed food, dairy products, red meat, gluten, and citrus foods. While some of these foods are common to causing eczema flare-ups, some of these foods are actually recommended to prevent eczema flare-ups.

What foods trigger eczema flare-ups?

Peanuts, milk, wheat, fish, and eggs most commonly trigger eczema flare-ups.

What is good to eat for eczema?

You may consider foods with anti-inflammatory properties, such as olive oil, vegetables, and foods containing vitamin E and vitamin D. Probiotics are another addition you could make to your diet. This type of diet has not been proven to be helpful as yet.

Anti-inflammatory foods may help reduce your eczema symptoms. These may include:

  • Fruits
  • Vegetables
  • Whole grains
  • Fatty fish (such as salmon or herring)
  • Fish oil containing omega-3 fatty acids, or an omega-3 supplement
  • Foods containing quercetin, a plant-based flavonoid (a powerful antioxidant and antihistamine) – apples, blueberries, broccoli, kale, spinach
  • Foods containing probiotics (such as yogurt, miso soup, soft cheeses, kefir, and tempeh). These help to support your immune system and may help reduce allergic reactions

It is always important to remember that foods considered to be good to eat for eczema may still cause a flare-up in you if you have an allergy to that food.

Are there specific diet plans for eczema?

There isn’t one specific eczema diet plan that will be suitable for everyone, and each individual will have foods that may or may not make their eczema worse.

  • Mediterranean diet – This diet includes foods such as fruits, vegetables, healthy fats, and fish. It may also contain very small amounts of red meat, sweet desserts, and red wine (which contains quercetin)
  • Dyshidrotic diet: This is specifically for those with dyshidrotic eczema (tiny blisters on your hands and feet) a type of eczema where you have a nickel sensitivity. Touching certain metal objects such as jewelry may cause an eczema flare-up. (The American Academy of Dermatology recommends those who are sensitive to nickel should also avoid foods containing nickel). Food allergens may also cause flare-ups and nickel and cobalt may make the symptoms worse. Food containing nickel and cobalt include whole grains, oat, baking powder, chickpeas, and canned foods. Foods high in vitamin C (such as oranges, cauliflower, pineapple, and mango) can help reduce the absorption
  • Elimination diet (for those who don’t know what their triggers are). Here you make one dietary change at a time. Eczema can also be caused by other factors other than the food you eat, making the diagnosis of the cause more difficult. Begin by removing certain food groups or specific foods for 3 days at a time to see if this has an effect on your eczema flare-up

What is the best milk for eczema sufferers?

Older children with mild eczema occasionally find that their eczema is better with sheep’s or goat’s milk instead of cow’s milk. Almond and coconut milk have been found to actually worsen eczema flare-ups.

What foods help eczema go away?

Fruits and vegetables such as apples, broccoli, blueberries, spinach, and kale help improve eczema flare-ups.

Would eating gluten-free foods help?

Celiac disease and eczema are closely associated with one another. Treatment for celiac disease involves removing gluten from your diet. Individuals with celiac disease or sensitivity to gluten and eczema can see an improvement in eczema flare-ups if gluten is removed from their diets.

What is the best way to prevent eczema flare-ups?

Eczema flare-ups can be caused by a number of factors, not just the food you eat. You can prevent or minimize flare-ups by wearing protective gloves, especially when coming into contact with environmental factors that can trigger a flare-up, using a recommended moisturizer after bathing or trying to reduce your stress levels.

Over-the-counter topical creams and treatments can help to reduce your symptoms of eczema. Also, allergy testing will help you determine what may cause your flare-ups and help you decide the best treatment for your eczema.

To help manage your symptoms of eczema make sure you eat a healthy diet with fruits, vegetables, healthy fats, and protein. This may help prevent some or all of your flare-ups.

Talk to your doctor or dermatologist if you’re planning to become pregnant and you have a family history of eczema. They will be able to give you medical advice for preventive measures to reduce your child’s chances of developing eczema.

Cosentyx side effects and how to avoid them

Cosentyx is a brand-name medication manufactured by Novartis Pharmaceuticals Corporation. It is classed as a biologic medication (biologics are drugs made from living cells) and is used for the treatment of inflammatory autoimmune diseases. While Cosentyx is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Cosentyx include upper respiratory tract infections. Less common, but more serious side effects, can include more serious infections.

Learn more about the side effects of Cosentyx and what you can do to avoid them.

What is Cosentyx (secukinumab)?

Cosentyx is a medication prescribed to adults who have one or more of the inflammatory autoimmune diseases. You may use it on its own or in combination with the drug methotrexate for:

  • Moderate to severe plaque psoriasis
  • Active psoriatic arthritis
  • Active ankylosing spondylitis, and active non-radiographic axial spondyloarthritis

Cosentyx may also be used to treat children and adolescents aged 4 years and older with active enthesitis-related arthritis.

Plaque psoriasis is a skin condition caused by a speeding up of the lifecycle of skin cells, likely triggered by your immune system. It causes cells to build upon the surface of your skin, resulting in red patches covered in silvery scales. These patches can occur in a few places or they can cover large areas of your body.

Psoriatic arthritis is a joint condition that’s related to plaque psoriasis and happens most often in people who have plaque psoriasis. It’s caused by inflammation in your joints. It can make joints stiff, swollen, and painful, and it can cause damage as cartilage and bone are lost over time. Psoriatic arthritis can affect any joint, but it’s most common in the fingers and toes.

Ankylosing spondylitis is a form of arthritis caused by inflammation in the joints of your spine and sometimes in your shoulders and hips. It can result in stiffness, pain, damage, and deformation of the joints over time.

The active ingredient secukinumab is classed as a monoclonal antibody. It reduces the amount of inflammation your immune system can cause. Your immune system triggers inflammation by releasing molecules called cytokines. Secukinumab works by binding with these cytokines. This stops the cytokines from working, reducing the amount of inflammation they can trigger.

Cosentyx dosage

Cosentyx is available in injection form:

  • 150 mg/mL in a single-dose Sensoready pen or in a single-dose prefilled syringe
  • 75 mg/0.5 mL in a single-dose prefilled syringe
  • 150 mg, lyophilized powder in a single-dose vial for reconstitution

Costenyx is often prescribed after a first round of medication has proven ineffective. Cosentyx is given as an injection under your skin (a subcutaneous injection). It can be done by a doctor or nurse, or by yourself using a pre-filled syringe or a Sensoready pen.

You are advised to read the medication guide and prescribing information provided with this medicine for the drug information and patient information and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cosentyx side effects

The most common possible side effects of Cosentyx in clinical trials include:

  • Injection site irritation
  • Upper respiratory tract infections
  • Cold symptoms such as stuffy nose, sneezing, sore throat
  • Cold sores (oral herpes)
  • Diarrhea
  • A runny nose (rhinorrhea)

Cosentyx can cause more serious side effects, including:

  • Serious infections – signs of infection such include fever, sweats, muscle aches, skin sores, diarrhea, stomach pain, pain when you urinate
  • Skin redness and shedding of large areas of skin, which may be itchy or painful
  • Anaphylaxis and serious allergic reactions can occur – feeling faint, swelling of your face, mouth, tongue, or throat, shortness of breath, trouble breathing, chest tightness, skin rash or hives .

If you experience any of these serious side effects, stop taking Cosentyx and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Cosentyx drug interactions

Monitor patients when starting or stopping treatment with Cosentyx if also taking CYP450 substrates

Before taking Cosentyx, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Cosentyx warnings & precautions

Don’t take Cosentyx if you:

  • Are allergic to the active ingredient secukinumab
  • Are allergic to any of the other ingredients in Cosentyx
  • Have an infection your physician thinks is serious
  • Are under 18 years of age

Talk to your doctor before taking Cosentyx if you:

  • Have an infection
  • Have recently had a vaccination
  • Have long-term or repeating infections
  • Have tuberculosis
  • Have Crohn’s disease
  • Have ulcerative colitis
  • Are undergoing any other treatments for plaque psoriasis, such as taking another immunosuppressant or ultraviolet (UV) light phototherapy
  • Have a latex allergy (the injection device used for Cosentyx may contain latex)
  • Have recently received or are scheduled to receive live vaccines (such as smallpox, chickenpox, and measles, mumps, rubella (MMR) vaccine)
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Cosentyx, to make sure it is safe for you.

Does Cosentyx cause cancer?

No, Cosentyx is not associated with cancer.

Does Cosentyx cause weight gain?

No, Cosentyx does not cause weight loss or weight gain.

Does Cosentyx cause neurological side effects?

Cosentyx does not cause tiredness but fatigue is a side effect of methotrexate which you may take alongside Cosentyx. Fatigue may also be a symptom of psoriatic arthritis or another condition that Cosentyx is used to treat.

Does Cosentyx cause depression?

No. Cosentyx is not known to cause depression or changes in mood changes.

What are Cosentyx’s rare side effects?

Rarely, Cosentyx can cause inflammatory bowel disease. Cosentyx may cause severe flare-ups if you already have inflammatory bowel disease.

Does Cosentyx cause hair loss?

Cosentyx is not known to cause hair loss.

Is Cosentyx a high-risk medication?

Cosentyx may weaken your immune system, and increase your risk of infection.

What can you not do with Cosentyx?

Do not drink alcohol if you are using methotreaxte in combination with Cosentyx. Alcohol may cause liver damage and make the symptoms of the condition you are treating worse.

Who should not take Cosentyx?

Cosentyx is not recommended for children under the age of 18 years. Cosentyx is only available with a doctor’s prescription.

What is the maximum dosage for Cosentyx?

Your loading dose and maximum dose of Cosentyx will be based on the condition you are being treated for and your body weight. This will be decided by your doctor.

Are there any risks with Cosentyx?

Costenyx reduces how well your immune system is able to fight infections and may increase your chances of developing a serious infection.

How to avoid Cosentyx side effects

The best way to avoid side effects is to take Cosentyx as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Cosentyx that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Cosentyx. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Cosentyx as it can increase your risk of liver problems and make the symptoms of the condition you are treating worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Cosentyx.

7. Know the signs and symptoms of Cosentyx side effects

Signs and symptoms of side effects include upper respiratory infections. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Cosentyx.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Cosentyx as needed.

Entyvio side effects and how to avoid them

Entyvio is a brand-name medication manufactured by Takeda Pharmaceuticals U.S.A., Inc. It is classed as a monoclonal antibody and is used to treat active ulcerative colitis and Crohn’s disease. While Entyvio is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Entyvio include joint and back pain. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Entyvio and what you can do to avoid them.

What is Entyvio (vedolizumab)?

Entyvio is a medicine prescribed to adults to treat moderate to severe Crohn’s disease and ulcerative colitis. It’s usually prescribed when another medicine hasn’t worked well enough or wasn’t well tolerated. There’s no permanent cure for either condition, but they can be managed with medications like Entyvio. It can help reduce the severity of your symptoms and prevent flare-ups.

The active ingredient in Entyvio is called vedolizumab, which is a biologic. It is a type of drug called a monoclonal antibody that reduces inflammation in your gastrointestinal system. When you take Entyvio, vedolizumab is released into your gastrointestinal system. It attaches itself to areas on the surface of your gut cells called integrin receptors.

Usually, when integrin receptors are stimulated by other molecules in your body, they trigger inflammation, but when vedolizumab binds with the integrin receptors it stops other molecules from stimulating them. This reduces how much inflammation occurs in your gastrointestinal system.

Entyvio dosage

Entyvio is available as an injection: 300 mg vedolizumab in a single-dose vial. Entyvio is injected into a vein in your arm using an intravenous drip (intravenous infusion). A doctor or nurse usually does this for you. How often you have intravenous infusions will be decided upon by your doctor based on your condition and medical history.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the most common Entyvio side effects?

The most common side effects of Entyvio include:

  • Headaches
  • Itching
  • Nausea (feeling sick)
  • Tiredness
  • Joint pain
  • Back pain
  • Pain in your hands and feet, and fingers and toes
  • Fever
  • Common colds
  • Increased risk of infections of your nose and throat
  • Sore throat
  • Sinus infections
  • Bronchitis
  • Flu

Entyvio can cause more serious side effects, including:

  • Serious allergic reactions to the medication can cause hives, swelling of your face and throat, heart palpitations, trouble breathing, and shortness of breath
  • An increased risk of serious infections – tell your healthcare provider if you think you have an infection – symptoms may include fever, muscle aches, shortness of breath, runny nose, sore throat, skin sores, tiredness, or pain during urination
  • Liver problems – symptoms include tiredness, loss of appetite, upper right side stomach pain, dark urine, or yellowing of the skin and eyes (jaundice)
  • A rare but serious viral brain infection called progressive multifocal leukoencephalopathy (PML), particularly in people with an already weakened immune system

If you experience any of these serious side effects, stop taking Entyvio and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Entyvio drug interactions

Entyvio can interact with other medications including:

Other medical conditions may affect your treatment with Entyvio so you should always seek medical advice from the healthcare professional prescribing your drugs. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

Entyvio warnings & precautions

Don’t take Entyvio if:

  • Are allergic to the active ingredient vedolizumab
  • Are allergic to any of the other ingredients in Entyvio
  • Are under 18 years of age

Talk to your doctor before taking Entyvio if you:

  • Have tuberculosis (TB) or have been in close contact with someone who has tuberculosis
  • Currently have an infection
  • Have any liver problems
  • Have recently had a vaccine or due to having a vaccine
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – This drug passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Entyvio, to make sure it is safe for you.

When do Entyvio side effects start?

Side effects may appear almost immediately, in response to the infusion. Others may take several days, or weeks to appear. Entyvio will take up to 6 months to be completely cleared from your system and some side effects may continue to appear during this time.

Does Entyvio weaken your immune system?

Entyvio does not affect the whole of your immune system as it only works on your gut and not your whole body.

Is Entyvio a cure for ulcerative colitis?

Entyvio is not a cure for ulcerative colitis but will calm the inflammation. Your treatment and dose will be based on how severe your condition is.

Does Entyvio affect the brain?

Entyvio may cause progressive multifocal leukoencephalopathy (PML), a potentially life-threatening infection that affects your brain.

How long do Entyvio side effects last?

Entyvio will stay in your system for up to 6 months after your last dose, so side effects may continue during this time.

Are there Entyvio side effects that last forever?

Side effects may last for up to 6 months after the last dose of Entyvio. Mild side effects will go away on their own, or after a slight change to your dose.

Is weight gain a side effect of Entyvio?

No, weight gain is not a side effect of using Entyvio.

How long do you stay on Entyvio?

Entyvio is a long-term treatment if your doctor decides that Entyvio is safe for you. If your symptoms do not reduce after 14 weeks of treatment, your doctor may stop you from taking the drug.

Is it hard to digest the food you eat while on Entyvio?

Entyvio will not affect how the food you eat is digested but foods high in insoluble fibers, lactose, and sugars can all cause unpleasant symptoms of ulcerative colitis. Speak to your dietitian for advice on healthy food options if you are being treated for this condition.

Does Entyvio cause hair loss?

No, hair loss is not a known side effect of Entyvio, but hair loss is common in people with (IBD). Other medications used to treat IBD may also cause hair loss. Talk with your doctor if you have concerns associated with hair loss.

What are the long-term Entyvio side effects?

Entyvio may cause long-term side effects such as progressive multifocal leukoencephalopathy, joint pain, and liver problems. Talk to your doctor if you develop for medical advice if you develop any of these side effects.

Does Entyvio cause cancer?

Cancer is not a side effect of using Entyvio. Patients taking this medication do not have an increased likelihood of developing cancer.

What is the best way to keep Entyvio side effects at a minimum?

The best way to avoid side effects is to take Entyvio as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Entyvio that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Entyvio. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is not known to interact with Entyvio. But alcohol may make symptoms of inflammatory bowel disease worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet regularly for any cuts, sores, or redness. Tell your doctor if you experience any problems with your feet while taking Entyvio.

7. Know the signs and symptoms of Entyvio side effects

Signs and symptoms of side effects may include serious allergic reactions. If you experience any of these symptoms speak to your doctor for medical advice immediately.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Entyvio.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Entyvio as needed.

Dexilant side effects and how to avoid them

Dexilant is a brand-name medication manufactured by Takeda Pharmaceuticals. It is classed as a proton pump inhibitor (PPI) and is used to heal erosive esophagitis (EE), provide heartburn relief, and treat GERD in adults and children 12 years of age and older. While Dexilant is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Dexilant include stomach pain and diarrhea. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Dexilant and what you can do to avoid them.

What is Dexilant (dexlansoprazole)?

Dexilant is approved by the U.S. Food and Drug Administration (FDA) for:

  • Healing of erosive esophagitis (inflammation of the esophagus)
  • Maintaining healing of EE and relief of heartburn
  • Treating heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD)

Dexilant is a proton pump inhibitor that contains the active ingredient dexlansoprazole. It reduces stomach acid secretion by binding and inhibiting the hydrogen-potassium ATPase pump (gastric proton pump) found within the parietal cells of your stomach. This allows peptic ulcers to heal as well as reduces symptoms of gastroesophageal reflux disease (GERD).

More information on what is Dexilant

Dexilant dosage

Dexilant is available as delayed-release capsules in strengths of 30mg and 60mg.

  • Take Dexilant exactly as prescribed by your healthcare provider. Do not stop taking Dexilant without talking to your doctor first
  • Dexilant can be taken with or without food
  • Swallow Dexilant capsules whole. If you have trouble swallowing Dexilant capsules, you can open the capsules and sprinkle the contents on a tablespoon of applesauce. Be sure to swallow the applesauce mixture right away. Do not chew the mixture
  • If you miss a dose of Dexilant, take it immediately. However, if it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not use an extra dose to make up for the missed dose
  • If you take too much Dexilant, call your doctor immediately or go to the nearest hospital or emergency room
  • Dexliant is a pregnancy category B as there are no adequate and well-controlled studies with dexlansoprazole in pregnant women. Discuss the risks of taking Dexilant while pregnant with your healthcare provider
  • It is not known whether Dexilant is excreted in breast milk. It was found in rat milk during animal studies. Discuss with your healthcare provider if you should remain on Dexilant while breastfeeding
  • Read the Instructions for use and medication guide with drug information that comes with your Dexilant prescription
  • Store Dexilant at room temperature between 68°F to 77°F (20°C to 25°C)

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

More information on Dexilant Dosage

Dexilant side effects

The most common possible side effects of Dexilant include:

  • Diarrhea
  • Stomach pain
  • Nausea
  • Upper respiratory tract infections
  • Vomiting
  • Flatulence (gas)

Some serious side effects of Dexilant include:

  • Severe diarrhea that may be due to Clostridium difficile
  • Bone fracture
  • Low magnesium levels
  • Lupus erythematosus
  • Serious allergic reactions (rash, face swelling, throat tightness, difficulty breathing)

If you experience any of these serious side effects, stop taking Dexilant and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the side effects of Dexilant on the stomach?

Common side effects of Dexilant on the stomach include stomach pain, stomach cramps, diarrhea, and gas. These side effects are more common in children.

Dexilant long-term side effects

You should always check with your doctor or pharmacist before taking any medication, including Dexilant, to make sure it is safe for you. Long-term use of Dexilant may cause further complications.

  • Stomach cancer – Some symptoms of acid reflux and heartburn can be due to stomach cancer. Notify your doctor if your symptoms don’t resolve while taking Dexilant or come back quickly after stopping this medication
  • Clostridium difficile-associated diarrhea – Dexilant can cause an increased risk of Clostridium difficile-associated diarrhea
  • Bone Fracture – Long-term Dexilant therapy may cause an increased risk for osteoporosis-related fractures of the hip, wrist, or spine
  • Vitamin B12 deficiency and magnesium low levels – Decreased magnesium and vitamin B12 levels have been reported rarely with prolonged treatment with drugs like Dexilant
  • Long-term use of Dexilant may make it harder for your body to absorb vitamin B12
  • Dexilant can cause kidney problems – symptoms may include fever, rash, nausea, loss of appetite, joint pain, urinating less frequently, blood in your urine, weight gain
  • Cutaneous or systemic lupus erythematosus may occur or worsen in patients receiving Dexilant. Notify your healthcare provider if you have joint pain or a skin rash that gets worse when exposed to the sun

Is Dexilant hard on the kidneys?

Dexilant may cause acute interstitial nephritis. This is inflammation of the kidney that can cause acute kidney failure or chronic kidney disease.

Is Dexilant a safe drug?

Dexilant is not recommended for use in children 2 years of age and younger. Long-term use of Dexilant may make you more prone to bone fractures.

What happens when you stop taking Dexilant?

Your symptoms of heartburn may return if you stop taking Dexilant. Your doctor may reduce your dose slowly over a period of several weeks to stop this from happening.

What is a good substitute for Dexilant?

There are other medications to treat heart failure that your healthcare professional can prescribe if Dexilant is not the right medication for you. Some FDA-approved alternative treatment options include:

  • Prilosec (omeprazole)
  • Prevacid (lansoprazole)
  • Nexium (esomeprazole)

When is the best time to take Dexilant?

Dexilant is best taken orally once daily, with or without food.

What is the difference between Dexilant and Nexium?

Dexilant is used in people with erosive esophagitis or symptoms of (GERD). Nexium is used in people with GERD, erosive esophagitis, heartburn, Helicobacter pylori infections, and conditions such as Zollinger-Ellison syndrome. Both can be used in adults and children. Dexilant is recommended for use in children 12 to 17 years of age. Nexium is recommended for use in children aged 1 to 17 years of age. Dexilant contains dexlansoprazole, Nexium contains esomeprazole as the active ingredient. Both drugs are classed as proton pump inhibitors.

Dexilant drug interactions

Dexilant can interact with other medications including:

When Dexilant is taken with other medications, they may interact and change how they work. It may also increase the severity of certain side effects or make them more likely to occur. Make sure your doctor is aware of all the medications you take, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some major drug interactions with Dexilant include:

  • Atazanavir should not be taken with Dexilent because atazanavir concentrations may be decreased
  • Dexilant may interfere with the absorption of pH-dependent drugs such as ampicillin, digoxin, itraconazole, ketoconazole, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, and iron
  • Patients taking warfarin may require regular monitoring for increased bleeding times
  • Taking tacrolimus with Dexilant may increase tacrolimus blood concentrations
  • Dexilant may increase serum levels of methotrexate
  • St. John’s wort and rifampin can decrease the amount of Dexilant in your body
  • Dexilant may reduce the antiviral effect of some antiretroviral drugs such as rilpivirine, atazanavir, and nelfinavir

How to avoid Dexilant side effects

The best way to avoid side effects is to take Dexilant as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Dexilant that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Dexilant. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Dexilant as it can increase your risk of side effects and gastrointestinal problems. Alcohol may also worsen the medical condition you are treating, such as heartburn caused by GERD and stomach ulcers.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Dexilant.

7. Know the signs and symptoms of Dexilant side effects

Signs and symptoms of side effects include diarrhea and stomach pain. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Weight gain is not normally a side effect of Dexilant. If you experience changes in your weight while taking Dexilant, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Dexilant.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Dexilant as needed.

Stelara side effects and how to avoid them

Stelara is an FDA-approved medication manufactured by Janssen Biotech, Inc. It is classed as a biologic immunosuppressant used to treat inflammatory diseases. While Stelara is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Stelara include injection site reactions and infections. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Stelara and what you can do to avoid them.

What is Stelara (ustekinumab)?

Stelara is specifically an interleukin-12 and interleukin-23 inhibitor drug containing the active ingredient ustekinumab. It is used to treat inflammatory diseases such as:

  • Moderate to severely active Crohn’s disease in adults
  • Moderate to severely active ulcerative colitis in adults
  • Moderate to severe plaque psoriasis in adults and children 6 years of age and older who may benefit from systemic therapy or phototherapy
  • Active psoriatic arthritis in adults (alone or with the drug methotrexate)

Crohn’s disease is caused by inflammation of your gastrointestinal tract. Inflammation can occur along any part of your gastrointestinal tract. It can cause stomach pain, diarrhea, fever, weight loss, tiredness, and even anemia and arthritis.

Ulcerative colitis causes inflammation and ulcers to form in your colon and rectum (your large intestine). It can cause abdominal pain, diarrhea, fever, weight loss, and anemia.

Psoriasis is a chronic autoimmune disease that can also cause inflammation. Plaque psoriasis is a skin condition caused by the speeding up of the lifecycle of skin cells. Cells build up on the surface of your skin, resulting in red patches covered in white to silver scales. These patches can occur in a few spots or they can cover large areas of your body.

Psoriatic arthritis happens when psoriasis causes your joints to become inflamed. It can be painful, and it can cause swelling that can damage the joints over time and lead to deformation. Psoriatic arthritis can affect any joint, but it’s most common in the fingers and toes.

Stelara helps with these conditions by reducing the amount of inflammation your immune system can cause. This can provide relief from symptoms and reduce any damage chronic inflammatory diseases may cause.

The active ingredient ustekinumab is a monoclonal antibody, which means it’s a kind of protein that binds with other specific proteins in your body. Ustekinumab works by binding with proteins produced by your immune system called cytokines. These proteins help to trigger your body’s inflammatory response. By binding with them, ustekinumab stops them from working, reducing the amount of inflammation your immune system causes.

Always check with your doctor or pharmacist before taking any medication, including Stelara, to make sure it is safe for you.

Stelara dosage

Stelara is available as a subcutaneous Injection: 45 mg/0.5 mL or 90 mg/mL in a single-dose prefilled syringe, injection: 45 mg/0.5 mL in a single-dose vial, or as an intravenous Infusion: 130 mg/26 mL solution in a single-dose vial.

Inject Stelara by subcutaneous injection using either a pre-filled syringe or an injectable pen. It is important to use a new needle each time to prevent the risk of infection. You may get injection site reactions such as redness, bruising, or irritation after administration, but this will settle down after a few hours. Your pharmacist or other healthcare providers can teach you how to give injections at home.

If you use Stelara to treat Crohn’s Disease, you will receive your first dose as an hour-long intravenous infusion in a medical setting by a healthcare professional. Your next doses will all be subcutaneous injections.

You are advised to read the prescribing information and medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Stelara?

The most common possible side effects of Stelara include:

  • Tiredness
  • Headaches, dizziness
  • Injection site reactions – itching, pain, redness or discoloration of the skin
  • Nausea, vomiting
  • Upper respiratory infections – common cold, bronchitis, sore throats, or sinus infection
  • Urinary tract infections
  • Vaginal yeast infections
  • Joint pain

Stelara can cause more serious side effects, including:

  • A rare (sometimes fatal) condition called PRES (posterior reversible encephalopathy syndrome) – new or worsening headaches, seizures, vision problems, and confusion
  • Serious heart symptoms such as fast or irregular heartbeats, shortness of breath, sudden dizziness, feeling lightheaded, or faint
  • Suppression of the immune system
  • Serious allergic reactions – feeling faint, swelling of your face, tongue, or throat, a tight chest, or skin rash
  • Serious infections such as tuberculosis – symptoms include fever, night sweats, loss of appetite, weight loss, and constant tiredness

If you experience any of these serious side effects, stop taking Stelara and seek medical help immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Stelara cause weight gain?

No, Stelara shouldn’t cause weight gain. Weight gain isn’t a reported side effect in studies for this drug.

Are there side effects of stopping Stelara?

No, stopping to take Stelara shouldn’t cause side effects. However, the condition you’re taking Stelara to treat may return or worsen.

Does Stelara cause any changes in mood or anxiety?

You shouldn’t experience any changes in mood or anxiety while taking Stelara. These are not reported side effects in studies of people taking this drug.

Stelara drug interactions

Stelara can interact with other medications including:

  • Other immunosuppressant drugs
  • Other psoriasis or psoriatic arthritis treatments, including UV light therapy
  • Live vaccinations
  • CYP450 substrate medicines, like warfarin or cyclosporine

Before taking Stelara, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Stelara warnings & precautions

Don’t take Stelara if you:

  • Are allergic to the active ingredient ustekinumab
  • Are allergic to any of the other ingredients in Stelara
  • Are allergic to latex (the needle cover on the prefilled syringe contains latex)
  • Have an active infection
  • Are under 12 years of age

Talk to your doctor before taking Stelara if you:

  • Have ever had any type of cancer (malignancies) including skin cancer
  • Have recently had a live vaccine
  • Have had a recent infection
  • Have any new or changing lesions within psoriasis areas or on normal skin
  • Are currently having another treatment for psoriasis or psoriatic arthritis
  • Are currently having, or have had, injections to treat allergies
  • Are over 65 years of age
  • Are pregnant or trying to become pregnant
  • Are breastfeeding or plan to breastfeed – This drug may pass into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Stelara, to make sure it is safe for you.

How to avoid Stelara side effects

The best way to avoid side effects is to take Stelara as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Stelara that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Stelara. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

There are no known interactions between Stelara and alcohol. You are advised however to not consume alcohol excessively while using Stelara.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Stelara.

7. Know the signs and symptoms of Stelara side effects

Signs and symptoms of side effects include upper respiratory infections. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Stelara does not cause weight gain. If you experience changes in your weight while taking Stelara, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Stelara.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Stelara as needed.

Vimpat side effects and how to avoid them

Vimpat is a brand-name medication manufactured by UCB, Inc. It is classed as an anticonvulsant used to treat partial-onset seizures in adults and children aged four years and older. While Vimpat is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Vimpat include dizziness and drowsiness. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Vimpat and what you can do to avoid them.

What is Vimpat (lacosamide)?

The active ingredient in Vimpat is called lacosamide. It’s an antiepileptic drug (AED) that reduces your chances of having seizures. Lacosamide works by stopping certain circuits in your brain cells (neurons), called voltage-gated sodium channels, from activating in a repetitive way.

Lacosamide still allows your neurons to send signals, so doesn’t stop them from working and doesn’t affect your brain function. But it does stop neurons that have been active for long periods from sending repeating signals over and over, which is what is thought to trigger epilepsy. Rather than affecting your whole brain, you can think of Vimpat as targeting and calming those brain cells which are most likely to give you a seizure.

Always check with your doctor or pharmacist before taking any medication, including Vimpat, to make sure it is safe for you.

Vimpat dosage

Vimpat is available in tablet form in the following doses: 50 mg, 100 mg, 150 mg, and 200 mg tablets, 200 mg/20 mL single-dose vial for intravenous use, and 10 mg/mL oral solution.

You usually take Vimpat twice a day, in the morning and evening, to keep your seizures at bay. Vimpat can be taken as a tablet or oral solution that’s swallowed, or by injection into a vein (intravenous injection). Adults can take Vimpat in any of these ways, and this will be decided upon by your doctor. Children aged between four and 17 should only take Vimpat orally either as a tablet or an oral solution.

If you miss a dose of Vimpat take it as soon as you remember, but skip the missed dose if it is almost time for your next dose.

Read the complete medication guide provided with this medicine for the full drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Vimpat side effects

The most common side effects of lacosamide in clinical trials compared to placebo include:

  • Headaches
  • Dizziness
  • Drowsiness
  • Double vision
  • Nausea

Vimpat can cause more serious side effects, including:

  • An increased risk of suicidal thoughts and actions
  • Drug reaction with eosinophilia and systemic symptoms (DRESS) – serious allergic reaction symptoms include fever, dark urine, headache, hives, stomach pain, tender lymph glands in the neck, groin, or armpit, unusual tiredness, or yellowing of eyes or skin (jaundice)
  • Serious heart symptoms – fast or irregular heartbeats, fluttering in your chest, chest pain, shortness of breath, sudden dizziness, feeling lightheaded, or faint
  • Hypoesthesia
  • Cerebellar syndrome
  • New or worsening seizures
  • Dyskinesia

If you experience any of these serious side effects, stop taking Vimpat and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are the long term side effects of taking Vimpat?

Antiepileptic drugs such as Vimpat may increase the risk of suicidal thoughts and behavior. Patients may also experience forgetfulness, itching skin. lack of appetite, and a loss of interest or pleasure.

Is weight gain a side effect of Vimpat?

Weight gain is not a common side effect of Vimpat, but it may cause weight loss. Get medical advice from your doctor if you experience weight loss with Vimpat.

Side effects of Vimpat and Keppra

Common side effects of Vimpat and Keppra include dizziness, drowsiness, and tiredness. Other side effects of Vimpat only include blurred vision, nausea, vomiting, loss of balance, shakiness, and headaches. Other side effects of Keppra only include loss of appetite, stuffy nose, hostility, nervousness, and weakness.

Vimpat side effects in elderly

Certain side effects may be more common in the elderly. These may include dizziness, a loss of balance, drowsiness, blurred vision, nausea, feeling tired, or memory problems may occur. Speak to your doctor for medical advice if you have these side effects.

Vimpat drug interactions

Vimpat can interact with other medications including:

  • Any other medications to treat seizures or epilepsy
  • Any medications taken for heart conditions
  • Any medications that can affect your heartbeat – carbamazepine, lamotrigine, or pregabalin
  • Any medications taken to treat fungal infections – fluconazole, itraconazole, or ketoconazole
  • Treatments for HIV infections – ritonavir
  • Antibiotics – clarithromycin or rifampicin
  • St. John’s wort

Before taking Vimpat, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Vimpat warnings & precautions

Don’t take Vimpat if you:

  • Are allergic to the active ingredient lacosamide
  • Have a known hypersensitivity to any of the other ingredients in Vimpat
  • Have a heart problem called second- or third-degree AV block

Talk to your doctor before taking Vimpat if you:

  • Are taking any of the medications that could interact with Vimpat
  • Have or have had depression, other mood disorders, suicidal thoughts, or suicidal behaviors
  • Have any heart problem (such as heart failure or myocardial ischemia)
  • Have any liver problems
  • Have any kidney problems
  • Have phenylketonuria (PKU) – The oral solution contains aspartame (a source of phenylalanine), which can make this condition worse
  • Have ever abused prescription medications, alcohol, or illegal drugs
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is unknown if this drug passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Vimpat, to make sure it is safe for you.

Other warnings you should know about

Antiepileptic drugs like Vimpat can increase the risk of suicidal thoughts and actions in some people. Seek urgent medical attention if you feel, or someone you care for who is taking Vimpat, feels they are at risk of suicide.

Vimpat is a federally controlled substance because it can be abused and can lead to drug dependence. Keep your Vimpat in a safe place and protect it from theft. Never give or sell your Vimpat to anyone else, it may harm them and is against the law.

Vimpat can cause side effects, like dizziness, sleepiness, and blurred vision, that can affect your ability to drive, operate machinery, or perform other dangerous tasks. Avoid these activities when taking Vimpat until you’re confident it doesn’t give you side effects that put you or others in danger.

Vimpat should not be given to children under four years of age and should not be given through intravenous injection to children aged four to 17.

How to avoid Vimpat side effects

The best way to avoid side effects is to take Vimpat as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Vimpat that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Vimpat. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Vimpat as it can increase your risk of side effects such as dizziness, drowsiness, and confusion.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your caregiver if you experience any problems with your feet while taking Vimpat.

7. Know the signs and symptoms of Vimpat side effects

Signs and symptoms of side effects include dizziness and drowsiness. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Weight gain is not a common side effect of Vimpat, but it may cause weight loss. If you experience weight loss while taking Vimpat, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Vimpat.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Vimpat as needed.

Free pill identifier tools

Need help identifying prescription, over-the-counter (OTC), brand name, generic pills and capsules? You can quickly identify drugs by using a free pill identifier tool.

By using an online pill identifier tool, you can identify a pill by the imprint code, color, or shape of the pill.

Pill identifier tools, also known as pill identifier wizards, are online tools that allow you to identify a pill by its appearance. These tools can be very helpful if you’re not sure what kind of pill you have, or if you need to find more information about a pill you’ve been prescribed.

Best free pill identifier (pill finder) tools

There are several free pill identifier (pill finder) tools available online that include drug images, drug names (including the brand and generic names), strength (dose) and other useful information for reference. The most popular prescription pill identifiers are:

Can I take a picture of a pill and identify it?

You can use a mobile pill identifier app such as the Smart Pill Identifier to take a photo of the pill and identify it.

When will I need to use a pill identifier tool?

If you happened to find a stray pill in your medicine cabinet, or know someone who mixed up their pills by mistake, using an online pill identifier tool can help you find out exactly what is in the pill before taking the wrong pill by mistake.

How to identify a pill using a pill ID tool

You can identify a pill by using a pill identifier tool. There are a few different ways to use a pill identifier tool. The most common way is to search by the pill’s appearance, such as its shape, color, or imprint code. You can also search by the pill’s imprint code, which is a unique code that is printed on the pill.

If you’re not sure what kind of pill you have, or if you’re having trouble using an online pill identifier database, you can always ask your doctor or pharmacist for help. They should be able to tell you what the pill is and provide more information about it.

How to identify a prescription drug or over-the-counter (OTC) medication?

If you have a pill but are unsure if it is a prescription or over-the-counter (OTC) medication, you can try using a pill identifier tool, also commonly referred to as a pill finder or pill ID tool. Most pill identifier tools will allow you to search by the pill’s imprint code, which is a unique code that is printed on the pill. If the pill does not have an imprint code, you can try searching by the pill’s appearance, such as its shape, color, or markings.

If you’re still not sure what kind of pill you have, or if you’re having trouble using an online pill identifier database, you can always ask your doctor or pharmacist for help. They should be able to tell you what the pill is and provide more information about it.

What do numbers on the pills mean?

The numbers on pills refer to the pill’s imprint code. The imprint code is a unique code that is printed on the pill. It can be used to identify a pill, and it can also be used to find more information about the pill.

If you’re not sure what the numbers on your pill mean, you can try using a pill identifier tool. Most pill identifier tools will allow you to search by the pill’s imprint code. If you’re still not sure what the pill is, or if you’re having trouble using an online pill identifier database, you can always ask your doctor or pharmacist for help. They should be able to tell you what the pill is and provide more information about it.

How to find a pill imprint code

The pill imprint code is a unique code that is printed on the pill. It can be used to identify a pill, and it can also be used to find more information about the pill. Once a pharmaceutical manufacturer submits a pill’s imprint code to the FDA (U.S. Food and Drug Administration), the imprint code will be stored in a database that health care professionals are able to access.

If you’re not sure where to find the pill imprint code, you can try looking on the pill’s packaging. The pill imprint code is usually printed on the side of the package. If you can’t find the pill imprint code on the packaging, you can try using a pill identifier tool. Most pill identifier tools will allow you to search by the pill’s appearance, such as its shape, color, or markings.

Why do some pills that contain the same active ingredient have different imprints?

Some pills that contain the same active ingredient may have different imprints because they are made by different manufacturers. The pill’s imprint code is usually assigned by the manufacturer, so it can be used to identify which manufacturer made the pill.

If you’re not sure why two pills that contain the same active ingredient have different imprints, you can try using a pill identifier tool. Most pill identifier tools will allow you to search by the pill’s imprint code. If you’re still not sure what the pill is, or if you’re having trouble using an online pill identifier database, you can always ask your doctor or pharmacist for help. They should be able to tell you what the pill is and provide more information about it.

Can multiple drugs have the same imprint?

Yes, multiple drugs can have the same imprint. This is because the pill’s imprint code is assigned by the manufacturer, so it can be used to identify which manufacturer made the pill.

If you’re not sure why two pills that contain the same active ingredient have different imprints, you can try using a pill identifier tool. Most pill identifier tools will allow you to search by the pill’s imprint code.

What if my pill has a logo?

Some pills have a logo instead of an imprint code. The pill’s logo can be used to identify the pill, and it can also be used to find more information about the pill. To identify the pill, ignore the logo and use an online pill identification tool to search for the imprint code that is on the pill.

What does it mean if a pill has no imprint?

If a pill has no imprint, it may be a vitamin, dietary supplement, or herbal pill. These types of pills are not regulated by the FDA, so they do not have to have an imprint code.

Why do some tablets have a line in the middle?

Some tablets have a line in the middle so that they can be split into two equal doses. The pill may be split along the line, or it may be broken into two pieces.

Who can help me identify a pill?

If you’re not sure what the pill is, or if you’re having trouble using an online pill identifier database (pill wizard), you can always ask your doctor or pharmacist for help. They should be able to tell you what the pill is and provide more information about it.

How can I tell if a pill is fake?

It’s very difficult to visually determine if a pill is fake. Pfizer recommends checking for misspellings in the product name, comparing the medication appearance to what you previously received at the local pharmacy, and issues with the medication quality (for example, if the pill is cracked or has bubbled-up coating)..

Which prescription drugs are most commonly abused?

Many prescription drugs that have been approved by the FDA are commonly abused. The most common classes of prescription drugs that are abused, according to the National Institute on Drug Abuse:

  1. Opioids that are used to treat pain
  2. Central nervous system (CNS) depressants, including benzodiazepines (Valium, Xanax, Klonipin, and Ativan), that are used to treat anxiety and sleep disorders
  3. Stimulants, including amphetamine and dextroamphetamine (Adderall) or methylphenidate (Concerta, Ritalin, Methylin, Daytrana) used for the treatment of attention deficit disorder (ADHD) and narcolepsy (a sleep disorder).

These pills can be identified with a pill identifier tool by searching the imprint codes, pill colors or shapes. A major concern is the number of illegal drugs that are in circulation that contain fentanyl-like ingredients, which are highly toxic and associated with many known deaths that are reported after taking a single pill.

How long does Xarelto stay in your system?

Xarelto is the brand name for a prescription drug that contains rivaroxaban as the active ingredient. Rivaroxaban is classed as an anticoagulant and is used to reduce the risk of blood clots forming in the body. Reducing blood clots will help with the prevention of strokes, DVTs, and pulmonary embolisms.

If your doctor has prescribed Xarelto to you, you may want to know more about what it is and how it works. Here we’ll explain what Xarelto is, what it’s used for, how it works, its side effects, what happens when you stop taking it, drug interactions, and much more.

What is Xarelto?

Xarelto (rivaroxaban) is an FDA-approved anticoagulant therapy manufactured by Bayer and Janssen Pharmaceuticals, Inc. It is a blood thinner used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). Xarelto belongs to a class of medications called direct Factor Xa inhibitors which reduce the chance of blood clots happening and also reduce the risk of coronary heart disease and peripheral artery disease.

What is Xarelto used for?

Xarelto (rivaroxaban) is an FDA-approved medication manufactured by Janssen Pharmaceuticals and Bayer to:

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (irregular heartbeat)
  • Treat deep vein thrombosis (DVT), and pulmonary embolism (PE), and reduce the risk of recurrence of DVT and PE
  • Prophylaxis of DVT, which may lead to PE in patients undergoing hip replacement surgery or knee replacement surgery
  • Prophylaxis of venous thromboembolism (VTE) in acutely ill medical patients
  • Reduce the risk of major cardiovascular events in patients with coronary artery disease (CAD)
  • Reduce the risk of major thrombotic vascular events in patients with peripheral artery disease (PAD)
  • Treatment of VTE and reduction in the risk of recurrent VTE in pediatric patients from birth to less than 18 years
  • Thromboprophylaxis in pediatric patients 2 years and older with congenital heart disease after the Fontan procedure
  • Prevention of atherothrombotic events in adults who have acute coronary syndromes and increased cardiac biomarkers in co-administration with antiplatelet agents

How does Xarelto work?

Blood clotting is a complex process that helps prevent excessive bleeding events when a blood vessel is injured. Sometimes blood clots form in your body when they are not needed, which can block the flow of blood and lead to stroke or heart attack (myocardial infarction).

The active ingredient in Xarelto is called rivaroxaban. It’s an oral anticoagulant drug, or blood thinner, that reduces the likelihood of clots forming in your blood. Based on Xarelto’s pharmacology, its mechanism of action is the inhibition of a clotting factor in your blood called factor Xa, which plays an important part in the coagulation of blood. By blocking this enzyme, it reduces your risk of blood clots forming. Rivaroxaban essentially has anti-factor Xa activity.

How long does it take for Xarelto to get into your system?

Xarelto will take 2 to 4 hours to reach its maximum plasma concentration and its full blood-thinning pharmacodynamic effect.

How long does Xarelto stay in your system?

Xarelto has a half-life of 5 to 9 hours and will typically take around 25 to 45 hours to clear from your bloodstream.

What is the half-life of Xarelto?

Xarelto has a half-life of 5 to 9 hours in healthy subjects.

What is the half-life of Xarelto in elderly

Xarelto has a half-life of 5 to 9 hours in healthy subjects and 11 to 13 hours in the elderly. Rivaroxaban’s pharmacodynamic effect is closely related to its plasma concentration.

What is rivaroxaban half-life in renal failure?

The clearance of rivaroxaban is reduced in elderly people, mainly due to reduced renal function in the elderly. The half-life of rivaroxaban in people with reduced renal function is 11 to 13 hours.

How long does it take for Xarelto to leave your system?

Xarelto takes around 25 to 45 hours to leave your system completely.

How is Xarelto cleared from the body?

One-third of rivaroxaban is cleared from the body unchanged through the kidneys. The other two-thirds is broken down by the liver. No active metabolites of Xarelto remain in circulation in the body.

How long do blood thinners stay in your system?

This will depend on the blood thinner you have been taking. Blood thinners such as warfarin or clopidogrel may take a few days. Xarelto and Eliquis on the other hand will wear off in around 24 hours.

Can you take Xarelto if you have a stomach ulcer?

You are not advised to take this medication if you have a stomach ulcer as you will be at an increased risk of bleeding from the ulcer and Xarelto may increase this risk.

When should I stop Xarelto for surgery?

Your last dose of Xarelto should be taken one or two days before surgery or any dental procedure. Xarelto has a half-life of 5 to 9 hours and will take around 24 hours to clear out of your system. Speak to your healthcare provider for medical advice if you are thinking about stopping your Xarelto for any reason.

What happens if you stop using Xarelto?

If you discontinue treatment with Xarelto you will be at an increased risk of heart attacks, DVT, strokes, or pulmonary embolism after around 24 hours due to a reduction in its anticoagulant effect.

Can you stop Xarelto cold turkey?

Xarelto does not cause withdrawal symptoms as such but if you stop treatment too early, you are at an increased risk of cardiovascular problems, such as heart attack or stroke.

What are the withdrawal symptoms of Xarelto?

Xarelto has a half-life of 5 to 9 hours and will typically take around 25 to 45 hours to clear from your bloodstream. During this time you may experience certain withdrawal symptoms. These symptoms will depend on how long it has been since you stopped taking Xarelto and what you were taking Xarelto for.

  • Side effects 12 to14 hours after discontinuing Xarelto include headache, feeling tired, feeling sick (nausea), dizziness, feeling light-headed, a dry mouth, easily bruised, back pain, weak legs, heart palpitations, high blood pressure, and risk of stroke or blood clots
  • Side effects 24 to 72 hours after discontinuing Xarelto may include more emotional effects such as depression or anxiety, feelings of restlessness, suicidal thoughts and behavior, difficulty sleeping and insomnia, difficulty thinking, confusion, and trouble concentrating

The side effects of withdrawal from Xarelto will begin to reduce and disappear 3-5 days after discontinuing Xarelto, with most of the withdrawal symptoms stopping after 1 week. You may however still experience emotional problems and are advised to speak to your doctor for medical advice if these types of symptoms continue to occur.

Is Xarelto withdrawal common?

Xarelto may cause complications if suddenly stopped. Your doctor will gradually reduce your dose of Xarelto so as to avoid any troublesome withdrawal symptoms.

Withdrawal symptoms may begin 12 to 14 hours after discontinuing treatment with Xarelto and continue for up to 7 days. The type of withdrawal symptoms you experience may differ depending on how long it has been since you stopped taking your medication.

The nature and extent to which you experience withdrawal symptoms will be specific to you, as we all react differently to treatments. Your withdrawal symptoms may however be more common if you have taken Xarelto for a longer period of time.

What is the first sign of Xarelto withdrawal?

The first signs of Xarelto withdrawal will be symptoms such as headache, feeling tired, nausea, dizziness, feeling light-headedness, dry mouth, easily bruised, back pain, leg weakness, heart palpitations, high blood pressure, and a risk of stroke or blood clots. These withdrawal symptoms will occur in the first 12 to 14 hours.

After 24 to 72 hours you may begin to experience more emotional withdrawal symptoms such as depression or anxiety, restlessness, suicidal thoughts and behavior, difficulty sleeping, problems thinking, confusion, and trouble concentrating.

What are the most common side effects of Xarelto withdrawal?

The most common side effects of Xarelto withdrawal will include symptoms such as headache, tiredness, nausea, dizziness, feeling light-headed, dry mouth, easy bruising, back pain, leg weakness, heart palpitations, high blood pressure, stroke or blood clots, depression or anxiety, restlessness, suicidal thoughts and behavior, difficulty sleeping, confusion, and trouble concentrating.

Not everyone will experience all of these withdrawal symptoms, or to the same extent. Speak to your doctor if you continue to suffer from these symptoms after discontinuing Xarelto.

How long do you need to wait before taking Xarelto again?

How often you take Xarelto will be based on your medical condition. Xarelto can be taken once or twice daily. Speak to your doctor for medical advice.

What happens if you take Xarelto and are allergic to it?

Your doctor will decide if you should continue to take Xarelto if you have had an allergic reaction. If you have had a serious allergic reaction speak to your healthcare provider right away or call 911 for emergency help.

How does Xarelto affect the liver?

You are recommended to avoid using Xarelto if you have moderate or severe hepatic impairment or any hepatic disease linked to coagulopathy as bleeding risk factors can be increased.

What are the side effects of Xarelto?

Common side effects of rivaroxaban in clinical trials compared to placebo include:

  • Back pain
  • Bruising
  • Heavy menstrual bleeding
  • Nosebleeds
  • Tiredness
  • Headache
  • Muscle spasms

Serious side effects of Xarelto

  • Serious bleeding
  • Spinal or epidural hematoma (bleeding around your spine). Consider the pharmacokinetic profile of Xarelto and place the catheter when Xarelto’s anticoagulant effect is low
  • Tarry stools
  • Vomiting blood or your vomit appears like coffee grounds
  • Bruising that lasts longer than normal

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How long do Xarelto’s side effects last?

Side effects should pass after a couple of days to a few weeks. Speak to your doctor for medical advice if side effects continue after this time.

How long can you stay on Xarelto?

Your doctor will decide how long you stay on Xarelto. You should not stop taking Xarelto suddenly or without your doctor’s medical advice. Speak to your doctor if you are considering stopping your treatment with Xarelto.

What are the risks of long-term use of Xarelto?

Discuss your medical condition with your doctor before starting treatment with Xarelto, as treatment with Xarelto may worsen and be contraindicated in certain conditions.

  • Epidural or spinal hematomas can result in long-term or permanent paralysis
  • Stopping Xarelto too early increases your risk of heart-related problems, such as heart attack or stroke
  • Xarelto causes an increased risk of bleeding which can cause serious and life-threatening. A reversal agent of rivaroxaban is available
  • Xarelto should be used with caution in pregnant women due to the potential for pregnancy-related hemorrhage
  • Xarelto is not recommended for use in patients with prosthetic heart valves
  • Xarelto is not recommended for use in patients with Triple Positive Antiphospholipid Syndrome
  • Xarelto is not recommended for use in patients with moderate renal function or severe renal impairment (creatinine clearance <15 mL/min)
  • Do not remove an indwelling epidural or intrathecal catheter until 18hr to 26hr have elapsed after the last administration. Do not administer the next dose until 6 hr after removal of the catheter
  • Tell your healthcare professional if you are pregnant or breastfeeding

Does Xarelto have drug interactions similar to warfarin (Coumadin)?

Xarelto, Eliquis (apixaban), and Pradaxa (dabigatran) have fewer drug interactions than older vitamin k antagonist VKA) anticoagulants such as warfarin and low molecular weight heparin, and will not require regular blood testing for INR or prothrombin time. You will however have a higher risk of bleeding with concomitant use of certain other treatments that also increase your risk of bleeding:

  • Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) – aspirin, ibuprofen, naproxen
  • Other blood thinners – warfarin, heparin, clopidogrel, (Plavix) enoxaparin
  • Other platelet aggregation inhibitors
  • Selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • HIV protease inhibitors – ritonavir
  • Azole antifungals – ketoconazole
  • Antibiotics – erythromycin
  • Anticonvuslants – carbamazepine, phenytoin
  • St. John’s wort
  • P-gp and strong CYP3A4 inhibitors or inducers

Certain medications may potentially block the effects of Xarelto and effectively cause withdrawal symptoms. Tell your healthcare provider about all the medicines you take, especially anything new that you have started taking after you began treatment with Xarelto. Remember to include prescription drugs, over-the-counter medications, herbal supplements and vitamins.

How do I take Xarelto?

  • Xarelto is available in 2.5 mg, 10 mg, 15 mg, and 20 mg tablets
  • Take Xarelto exactly as prescribed by your healthcare provider. Do not change your daily dose of rivaroxaban or stop taking this medication unless instructed by your doctor
  • Oral bioavailability of rivaroxaban is 80 to 100% for the 10 mg dose. Xarelto is usually taken with an evening meal
  • Your dose of Xarelto will depend on your body weight or age and dose adjustments do not need to be made
  • Xarelto may need to be stopped for a few days before any surgery or medical or dental procedure. Your doctor will tell you when to stop taking Xarelto and when to start taking it again after your procedure
  • Xarelto is taken as an oral administration. If you have trouble swallowing pills, you can crush Xarelto tablets and mix them with soft foods to eat, like applesauce, immediately before use
  • If you miss a dose of Xarelto while taking it twice a day, take the missed pill as soon as you remember that you missed it, on the same day. You can only take 2 doses of this medication at the same time to make up for the missed dose. Take your next dose at your regularly scheduled time. If you are taking Xarelto once a day, take the missed dose as soon as you remember on the same day. Take your next dose at your regularly scheduled time
  • If you take too much Xarelto, you should visit the nearest hospital emergency room as soon as possible or call your doctor right away
  • Please read the full prescribing information, including the boxed warnings, and the medication guide
  • Xarelto tablets and suspension should be stored at room temperature away from heat, direct light, and moisture. Store the syringes and bottle upright in the original carton for Xarelto suspension. Do not freeze Xarelto suspension and discard it after the “Discard after” date that is written on the bottle

Is it better to take Xarelto in the morning or evening?

Xarelto is better taken once daily with your evening meal. Take your dose of Xarelto as soon as you can if you miss a dose.

Why is Xarelto taken at night?

Xarelto is taken in the evening to reduce your risk of a stroke.

How long does Eliquis stay in your system?

Eliquis is the brand name for a prescription drug that contains apixaban as the active ingredient. Apixaban is classed as an anticoagulant medication and is used to reduce the risk of blood clots forming in the body due to a variety of medical conditions in adults. Blood clots are semi-solid clumps of red blood cells, fibrin, platelets, and other proteins.

If your doctor has prescribed Eliquis to you, you may want to know more about what it is and how it works. Here we’ll explain what Eliquis is, what it’s used for, how it works, its side effects, drug interactions, and more.

What is Eliquis?

Eliquis is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Bristol-Myers Squibb and Pfizer for adults 18 years and older. The safety and efficacy of Eliquis in children and adolescents below age 18 have not been established.

RELATED: What is Eliquis?

What does it mean if you have a clot in your blood?

Blood clotting is a complex process that helps prevent excessive bleeding when a blood vessel is injured. Sometimes blood clots form in your body when they are not needed, which can block the flow of blood and lead to stroke or heart attack.

What is Eliquis used for?

Eliquis is a clotting factor inhibitor that stops your blood from clotting. It is approved to treat the following:

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib)
  • Prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients who have undergone hip or knee replacement surgery
  • Treatment for the prevention of venous thromboembolism (VTE), and for the reduction in the risk of recurrent DVT and PE following initial therapy

How does Eliquis work?

Blood clotting involves the coagulation cascade and platelet activation process that helps prevent excessive bleeding when a blood vessel is injured. Apixaban the active ingredient in Eliquis reduces the likelihood of clots forming in your blood. It works by blocking an enzyme in your blood called factor Xa, which plays an important part in the blood clotting process. By blocking this enzyme, it reduces your risk of blood clots forming.

How long does it take for Eliquis to get into your system?

Eliquis achieves maximum levels in your body within 3 to 4 hours of being taken orally. The effects of Eliquis on blood clotting factors are seen within a few hours.

How long does Eliquis stay in your system?

Eliquis has a half-life of around 12 hours and will remain in your system for around 24 hours after your last dose.

How long do other blood thinners stay in your system?

The amount of time other blood thinners stay in your system depends on the medication, and may range from hours to days. For example, the effects of blood thinning with Plavix (clopidogrel), aspirin and warfarin can last for days, while the effects of blood thinning with Xarelto (rivaroxaban) and Eliquis (apixaban) typically wear off in around one day.

How long does it take for Eliquis to leave your system?

Eliquis will take around 24 hours for its clotting effects to wear off and completely leave your system.

How long does it take for blood thinners to wear off?

This will depend on the blood thinner you have been taking. Blood thinners such as warfarin or clopidogrel may take a few days. Eliquis and Xarelto on the other hand will wear off in around 24 hours.

What is the difference between Eliquis and other blood thinners?

In comparison to warfarin, Eliquis causes less episodes of bleeding, does not require regular blood tests for the INR, has less drug interactions, and is not affected by the intake of vitamin K.

How is Eliquis cleared from the body?

Eliquis is cleared from the body through the liver, kidneys, intestine, and through metabolism.

Can you take Eliquis if you have a stomach ulcer?

You are not advised to take Eliquis if you have a stomach ulcer as you will be at an increased risk of bleeding from the ulcer and Eliquis may increase this risk.

When should I stop Eliquis?

Treatment with Eliquis should be stopped one or two days before surgery or any dental procedure. Speak to your doctor for medical advice if you are thinking about stopping your Eliquis.

What happens when you stop taking Eliquis?

If you discontinue treatment with Eliquis you will be at an increased risk of heart attacks, DVT, strokes, or pulmonary embolism after around 24 hours.

Can you stop Eliquis cold turkey?

Eliquis does not cause withdrawal symptoms but if you stop treatment too early, you are at an increased risk of cardiovascular problems, such as heart attack or stroke.

How long do you need to wait before taking Eliquis again?

Eliquis is taken twice daily (every 12 hours). Speak to your doctor for medical advice about how to take Eliquis.

What happens if you take Eliquis and are allergic to it?

Your doctor will decide if you should continue to take Eliquis if you have had an allergic reaction. If you have had a serious allergic reaction speak to your healthcare provider right away or call 911 for emergency help.

What are the side effects of Eliquis?

The most common side effects of Eliquis in clinical trials include:

  • Back pain
  • Bruising
  • Heavy menstrual bleeding
  • Nosebleeds
  • Bleeding gums

In rare instances, Eliquis can cause more serious side effects. These can include:

  • Major bleeding which can cause serious and life-threatening.
  • Spinal or epidural hematoma (bleeding around your spine)</li
  • Tarry stools
  • Vomiting blood or your vomit looks like coffee grounds
  • Red, pink, or brown urine, red or black stools
  • Allergic reaction (hives, chest pain, wheezing, trouble breathing, swelling of your face, lips)

Your doctor will assess the benefits of using Eliquis against your risk of side effects. Make sure to read the full prescribing information, including the boxed warnings and the medication guide to learn more about this medication.

Patients are encouraged to report negative side effects or adverse reactions of Eliquis to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

RELATED: Eliquis side effects and how to avoid them, Side effects of Eliquis in the elderly

How long do Eliquis’s side effects last?

Side effects should pass after a couple of days to a few weeks. Speak to your doctor for medical advice if side effects continue after this time.

What are the risks of long-term use of Eliquis?

Discuss your medical condition with your doctor before starting treatment with Eliquis, as treatment with Eliquis may worsen certain conditions such as if you:

  • Have active pathological bleeding
  • Are taking any of the medications that could interact with Eliquis
  • Are breastfeeding or are planning to breastfeed
  • Are pregnant or plan to become pregnant. Eliquis should be used with caution in pregnant women due to the potential for pregnancy-related hemorrhage.
  • Have an artificial heart valve
  • Have Triple Positive Antiphospholipid Syndrome.
  • Have an intrathecal catheter
  • Have kidney or liver problems
  • Have bleeding problems or any other medical condition that increases your bleeding risk

Does Eliquis have drug interactions similar to warfarin (Coumadin)?

Eliquis (apixaban), Xarelto (rivaroxaban), and Pradaxa (dabigatran) are low risk for drug interactions compared to older, high-risk anticoagulants such as warfarin. You will however have a higher risk of bleeding if you take certain other treatments that may also increase your risk of bleeding:

  • Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) – aspirin, ibuprofen, naproxen
  • Other blood thinners – warfarin, heparin, clopidogrel (Plavix)
  • Selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Azole antifungals – ketoconazole
  • Antibiotics – erythromycin
  • Anticonvuslants – carbamazepine, phenytoin
  • St. John’s wort

Tell your healthcare provider about all the medicines you take, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.

How do I take Eliquis?

Eliquis is available in tablet form, in the following doses: 2.5 mg and 5 mg tablets.

The recommended dose of Eliquis is 5 mg orally twice daily. For elderly patients 80 years of age or older, weighing 60 kg or less, or having serum creatinine equal to or above 1.5 mg/dL, the recommended dose is 2.5 mg orally twice daily.

If you are unable to swallow the tablets whole, you may crush them and mix them with water, apple juice, or applesauce and take them orally. Crushed tablets may also be mixed with 60 mL of water and given through a nasogastric tube.

If you take heparin, warfarin, Coumadin, or Jantoven, your doctor will give you instructions about how to switch to apixaban. You do not need to monitor your Vitamin K intake while taking Eliquis. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the normal time.

You are advised to read the medication guide provided with this medicine for the full drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Remicade side effects and how to avoid them

Remicade is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Janssen Biotech, Inc. It is classed as a tumor necrosis factor-alpha inhibitor and is used to treat inflammatory autoimmune diseases. While Remicade is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Remicade include an increased risk of infections. Less common, but more serious side effects, can include kidney or liver injury.

Learn more about the side effects of Remicade and what you can do to avoid them.

What is Remicade (infliximab)?

Remicade contains infliximab as the active ingredient. It is a biologic drug made from living organisms. Remicade is used alone or in combination with methotrexate to treat inflammatory autoimmune diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It can also be used to treat similar inflammatory conditions, such as Crohn’s disease, and ulcerative colitis.

Infliximab reduces the inflammation caused by some autoimmune and inflammatory diseases. Inflammation is a natural process your immune system uses to clear itself of infections. When your immune system detects infections, or when it accidentally attacks normal cells in your body, it releases a substance called TNF. TNF travels to the site of infection where it triggers inflammation.

Infliximab blocks this process. It binds with TNF, stopping it from working, and reducing your levels of inflammation. This can ease the symptoms of your disease, limit the damage they can cause, and reduce the severity and frequency of flare-ups.

Always check with your doctor or pharmacist before taking any medication, including Remicade, to make sure it is safe for you.

Remicade dosage

Remicade is available in lyophilized powder form, in the following doses: 100 mg in a 20 mL vial for intravenous infusion. The dose you receive will be based on your age, weight, and the condition you are being treated for.

You are advised to read the medication guide provided with this medicine for the complete drug information and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Remicade side effects

The most common side effects of Remicade include:

  • Stomach pain
  • Nausea
  • Headaches
  • Higher risk of infections, such as upper respiratory (sinus infections and sore throat) and viral infections

More serious side effects of Remicade include

  • Delayed allergic reactionsfever, hives, sore throat, shortness of breath, difficulty swallowing, headache, high or low blood pressure, joint or muscle pain, skin rash, or swelling in your face or hands
  • Infusion reactions
  • Reduced white blood cells
  • Heart problems and heart failure – new or worsening symptoms including shortness of breath, swelling of ankles and feet, unusual tiredness, lightheadedness, sudden weight gain
  • Liver problems and liver failure – upper right-sided abdominal pain, loss of appetite, yellowing of your skin or eyes (jaundice)
  • Nervous system disorders
  • Lupus-like syndrome – chest pain or discomfort that does not go away, trouble breathing, joint pain, rash that gets worse in the sun
  • Certain forms of cancer such as skin cancer
  • Increased risk of serious infections (such as TB, bacterial sepsis, or invasive fungal infections) – symptoms may include fever, tiredness, cough, flu-like symptoms, weight loss, red or painful skin, or open sores

If you experience any of these serious side effects, stop taking Remicade and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Remicade drug interactions

Remicade can interact with other medications including:

  • Any medications that affect your immune system
  • Other treatments for rheumatoid arthritis – anakinra, tocilizumab
  • Other treatments for autoimmune diseases – abatacept
  • Live vaccines (such as BCG)
  • Corticosteroids – betamethasone, cortisone, dexamethasone
  • Antisphychotics – clozapine
  • Immunosuppressants – fingolimod, ozanimod, siponimod

Before taking Remicade, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Remicade warnings & precautions

Don’t take Remicade if you:

  • Are allergic to the active ingredient infliximab
  • Are allergic to any of the other ingredients in Remicade
  • Are allergic to proteins that come from mice
  • Have had moderate to severe heart failure
  • Have tuberculosis (TB) or another serious infection like pneumonia or sepsis

Talk to your doctor before using Remicade if you:

  • Have been treated with Remicade before
  • Have any form of infection
  • Have ever lived in or traveled to regions where infections called histoplasmosis, coccidioidomycosis, or blastomycosis are common
  • Have any type of cancer or a risk for developing cancer, such as chronic obstructive pulmonary disease (COPD)
  • Have had phototherapy for psoriasis
  • Have ever had tuberculosis (TB) or been in close contact with someone who has
  • Are a carrier of hepatitis B virus or you have ever had it
  • Have had mild heart failure or any other heart problems
  • Have ever had lymphoma (a type of blood cancer)
  • Are a heavy smoker
  • Have or have ever had a condition that affects your nervous system, like multiple sclerosis or Guillain-Barre syndrome
  • Have any fistulae (abnormal skin openings)
  • Have recently had a vaccine, or are due to have one
  • Are scheduled to have an operation or dental procedure
  • Are under six years of age
  • Are over 65 years of age
  • Are pregnant or trying to become pregnant
  • Are breastfeeding or plan to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Remicade, to make sure it is safe for you.

Other warnings you should know about

Fatal hepatosplenic T-cell lymphoma (HSTCL) has been reported in people treated with TNF blockers. Almost all had previously received azathioprine or 6-mercaptopurine at the same time as a TNF-blocker. Most cases have been reported in patients with Crohn’s disease or ulcerative colitis, in adolescents or young adult males.

How to avoid Remicade side effects

The best way to avoid side effects is to take Remicade as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Remicade that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Remicade. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

There are no reported interactions between Remicade and alcohol. However, avoid drinking alcohol excessively while taking Remicade as it can increase your risk of side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Remicade.

7. Know the signs and symptoms of Remicade side effects

Signs and symptoms of side effects include stomach pain, nausea, and headaches. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Remicade may cause sudden weight gain due to heart failure. If you experience this side effect while taking Remicade, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Remicade.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Remicade as needed.

Caplyta side effects and how to avoid them

Caplyta is an FDA-approved medication manufactured by Intra-Cellular Therapies, Inc. It is classed as an atypical antipsychotic medication and an antidepressant and is used for the treatment of schizophrenia or depressive episodes associated with bipolar depression. Caplyta is not approved to treat bipolar disorder. While Caplyta is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Caplyta include weight gain and increased cholesterol levels. Less common, but more serious side effects, can include seizures and hypoglycemia.

Learn more about the side effects of Caplyta and what you can do to avoid them.

What is Caplyta (lumateperone)?

Caplyta is the brand name for the active ingredient lumateperone. The mechanism of action of lumateperone for the treatment of schizophrenia or bipolar depression is not fully understood. However, its effectiveness could be through a combination of blocking the activity at central serotonin 5-HT2A receptors and central dopamine D2 receptors.

In clinical trials, after one week of treatment with Caplyta, patients started to show improved Positive and Negative Syndrome Scale (PANSS) total scores. PANSS is a scale used to measure the severity of schizophrenia symptoms. Symptoms continue to improve the longer you take the drug.

Caplyta dosage

Caplyta is available in capsule form, in the following doses: 42mg.

The recommended dosage of Caplyta is 42 mg once daily, with food, to control the symptoms of schizophrenia. Dose titration is not required. Caplyta can be taken alone or in combination with lithium or valproate for bipolar depression.

Read the medication guide provided with this medicine for the complete drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Caplyta side effects

The most common possible side effects of Caplyta compared to placebo include:

  • Weight gain
  • Increase in cholesterol and triglyceride levels
  • Somnolence (sleepiness)
  • Sedation (drowsiness)
  • Dry mouth

Caplyta can cause more serious side effects, including:

  • Orthostatic hypotension and syncope – feeling lightheaded, dizzy, or faint when you stand up or get up from a lying down position
  • Tardive dyskinesia – uncontrolled muscle movements in your face such as chewing, lip-smacking, frowning, tongue movement, blinking, or eye movement
  • Tightness in your neck or throat, difficulty swallowing
  • Problems controlling your body temperature
  • Metabolic changes such as diabetes mellitus and hyperglycemia
  • Problems breathing or speaking
  • Seizures
  • High blood sugar – increased thirst and urination, dry mouth, fruity breath odor
  • Low white blood cell counts (agranulocytosis) – fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing
  • Neuroleptic malignant syndrome (NMS) – high fever, confusion, changes in your breathing, heart rate, and blood pressure, stiff muscles, and increased sweating

If you experience any of these serious side effects, stop taking Caplyta and seek medical attention immediately. You are encouraged to report adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Caplyta drug interactions

Caplyta can interact with other medications including:

  • CYP3A4 inducers – carbamazepine, phenytoin, rifampin, St. John’s wort
  • Moderate or strong CYP3A4 inhibitors –  fluvoxamine, verapamil, clarithromycin, grapefruit juice
  • UGT inhibitors – valproic acid, probenecid

Before taking Caplyta, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Caplyta warnings & precautions

Don’t take Caplyta if you:

  • Are allergic to the active ingredient lumateperone
  • Have had an allergic reaction to any of the other ingredients in Caplyta
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Caplyta if you:

  • Are taking any of the medications that could interact with Caplyta
  • Have difficulty swallowing
  • Have high cholesterol or triglycerides
  • Have diabetes
  • Have liver disease
  • Are pregnant or are planning to become pregnant –  babies exposed to Caplyta in the third trimester have had withdrawal symptoms and extrapyramidal symptoms after birth

You should always check with your doctor or pharmacist before taking any medication, including Caplyta, to make sure it is safe for you.

Other warnings you should know about

Caplyta has a boxed warning and older adults with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.

Increased risk of suicidal thoughts or behaviors in children and young adults – watch for new or worsening symptoms of depression, especially changes in mood, feelings, or thoughts.

How to avoid Caplyta side effects

The best way to avoid side effects is to take Caplyta as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Caplyta that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Caplyta. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Caplyta as it can increase your risk of side effects such as nausea, vomiting, and sleepiness.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Caplyta.

7. Know the signs and symptoms of Caplyta side effects

Signs and symptoms of side effects include drowsiness and dry mouth. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Caplyta may cause weight gain. If you experience this side effect while taking Caplyta, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Caplyta.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Caplyta as needed.

Restasis side effects and how to avoid them

Restasis is a brand-name medication manufactured by Allergan Inc. It is classed as a topical immunomodulator used to increase the production of tears in patients who have eye swelling. While Restasis is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Restasis include eye pain and problems with vision.

Learn more about the side effects of Restasis and what you can do to avoid them.

What is Restasis (cyclosporine)?

Restasis eye drops are used to treat chronic dry eye disease (dry eye syndrome) that may be caused by inflammation. It is a topical immunomodulator used to increase tear production in patients whose tear production is suppressed due to ocular inflammation (in the eyes and tear ducts) associated with keratoconjunctivitis sicca. Increased tear production was not seen in patients currently taking topical anti-inflammatory drugs or using punctual plugs. Restasis is not approved for the treatment of blepharitis (eyelid inflammation).

Restasis dosage

Restasis is available as cyclosporine ophthalmic emulsion, containing cyclosporine 0.5mg/mL. It comes in single-use vials and Restasis multidose which comes in a bottle that can be used multiple times.

Instill one drop of the ophthalmic emulsion twice a day in each eye, every 12 hours. The single-use vial has to be thrown away after you use it, as the vials don’t contain any preservatives.

Wait at least 15 minutes before using artificial tears, or any other eye drops. Do not touch the dropper on any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an eye infection. Also, to avoid potential eye injury and contamination, be careful not to touch the vial tip to your eye.

Do not use this medicine while wearing contact lenses. Contact lenses may be reinserted 15 minutes following the administration of Restasis eye drops. Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

If you miss a dose, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Use your next dose at the normal time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition. If you think you’ve taken too much of this drug, call your doctor or call the American Association of Poison Control Centers at 800-222-1222.

Restasis side effects

The most common possible side effects of Restasis include:

  • Ocular burning sensation
  • Eye redness
  • Itchy eyes
  • Discharge, watery eyes
  • Blurred vision
  • Eye pain, eye irritation, foreign body sensation

If you experience more serious side effects, stop taking Restasis and seek medical attention immediately. You are encouraged to report the adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Restasis drug interactions

Restasis can interact with other medications including:

  • Ophthalmic treatments for glaucoma – betaxolol, levobunolol, timolol
  • Steroid eye treatments – dexamethasone, prednisolone

Before taking Restasis, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Restasis warnings & precautions

Don’t take Restasis if you:

  • Are allergic to the active ingredient cyclosporine
  • Have had an allergic reaction to any of the other ingredients in Restasis

Talk to your doctor before using Restasis if you:

  • Are taking any of the medications that could interact with Restasis
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It’s not known if Restasis passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Restasis, to make sure it is safe for you.

How to avoid Restasis side effects

The best way to avoid side effects is to take Restasis as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Restasis that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

Dry eye syndrome is a common problem associated with type 1 and type 2 diabetes. High blood sugar can cause nerve damage in your eyes leading to decreased tear production. If you have diabetes, it is important to monitor your blood sugar levels closely while taking Restasis. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol is not known to interact with Restasis. However, drink alcohol in moderation as excessive alcohol consumption is known to cause health problems such as heart disease.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Restasis.

7. Know the signs and symptoms of Restasis side effects

Signs and symptoms of side effects include blurry vision and eye pain. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Restasis may cause weight gain. This is more common in females over the age of 60, that have been using Restasis for less than 1 month. If you experience weight gain while taking Restasis, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your eye doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Restasis.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Restasis as needed.

Rexulti side effects and how to avoid them

Rexulti is a brand-name medication manufactured by Otsuka America Pharmaceutical, Inc. It is classed as an atypical antipsychotic and is used in combination with other antidepressants for the treatment of mental illnesses such as major depressive disorder (MDD) and the symptoms of schizophrenia. While Rexulti is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Rexulti include constipation and diarrhea. Less common, but more serious side effects, can include seizures and allergic reactions.

Learn more about the side effects of Rexulti and what you can do to avoid them.

What is Rexulti (brexpiprazole)?

Rexulti is a medicine prescribed to adults who have major depressive disorder or schizophrenia. If you have major depressive disorder, Rexulti is often prescribed alongside your current antidepressant when that antidepressant isn’t effectively treating your depression.

The active ingredient in Rexulti is called brexpiprazole which reduces your symptoms of depression or schizophrenia by changing the levels of two neurotransmitters in your brain (serotonin and dopamine). Neurotransmitters allow chemical signals to pass between the cells in your brain (neurons) and help regulate brain functions such as thinking, emotion, mood, learning, motivation, reward, and many others.

Rexulti dosage

Rexulti is available in tablet form, in the following doses: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg.

Take Rexulti once daily with or without food. Your exact dosage will be based on your age and the condition you are being treated for. If you miss a dose, take it as soon as you remember. Skip the missed dose if it is almost time for your next dose.

You are advised to read the prescribing information and medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Rexulti side effects

The most common possible side effects of Rexulti include:

  • Weight gain
  • Indigestion
  • Constipation
  • Diarrhea
  • Tremors
  • Sedation
  • Tiredness
  • Restlessness/feeling like you need to move (akathisia)

Rexulti can cause more serious side effects, including:

  • An increased risk of suicidal thoughts and suicide, particularly in young adults
  • Considerable weight gain
  • Strokes, particularly in elderly people
  • Severe allergic reactions to the medication – rash, itching, swelling of the face, tongue, or throat, severe dizziness, trouble breathing
  • Neuroleptic Malignant Syndrome (NMS) – a rare but potentially fatal condition caused by a reaction to the medication
  • Tardive dyskinesia – uncontrolled body movements, often in your face and tongue
  • High blood sugar (hyperglycemia) – increased thirst and/or urination, dry mouth, fruity breath odor
  • High cholesterol and triglycerides – this may increase your risk of developing heart disease and diabetes
  • Low white blood cell counts
  • Low blood pressure (orthostatic hypotension)
  • Unusual urges and an increase in impulsive behaviors, including sexual urges, gambling, compulsive eating, and compulsive shopping
  • Seizures
  • Problems with swallowing, that can cause food or liquid to get into your lungs
  • Difficulty controlling body temperature that can lead to you overheating and getting dehydrated

If you experience any of these serious side effects, stop taking Rexulti and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Rexulti drug interactions

Rexulti can interact with other medications including:

  • Any other antidepressants – fluoxetine, paroxetine
  • Any other medications that can affect your serotonin or dopamine levels
  • Any other medications taken to treat mental states and conditions, like mood and thought disorders, anxiety, or psychotic disorders
  • An herbal supplement called St. John’s Wort

Before taking Rexulti, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Rexulti warnings & precautions

Don’t take Rexulti if:

  • Are allergic to the active ingredient brexpiprazole
  • Are allergic to any of the other ingredients in Rexulti
  • You are an older adult with dementia-related psychosis, due to an increased risk of death
  • Are under 18 years of age

Talk to your doctor before taking Rexulti if you:

  • Are taking any of the medications that could interact with Rexulti
  • Have previously had suicidal thoughts or have tried to commit suicide
  • Have a family history of diabetes
  • Have high levels of blood fats, like cholesterol or triglycerides
  • Have ever had seizures (convulsions)
  • Have high blood pressure
  • Have heart problems
  • Have, or have had a stroke
  • Have, or have had, a low white blood cell count
  • Are pregnant – Taking antipsychotic medication in the final 3 months of pregnancy may cause problems with breathing or feeding, extrapyramidal symptoms (uncontrolled movements), and withdrawal symptoms in the newborn
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Rexulti, to make sure it is safe for you.

Other warnings you should know about

Antidepressants can increase your risk of suicidal thoughts and suicide, especially in children and young adults, often during the first few months of treatment. Rexulti is not for use in children, but young adults taking it should be monitored for signs of sudden changes in behavior, mood, thoughts, or feelings. Seek urgent medical attention if you, or someone you care for notice worsening depression or other psychiatric conditions.

Stopping Rexulti suddenly can cause a condition called discontinuation syndrome. This can cause withdrawal-like side effects, some of which can be serious. Talk to your doctor if you want to stop taking Rexulti. They may decrease your dose slowly to avoid discontinuation syndrome.

Rexulti can cause drowsiness which can impair your ability to drive, use machinery, or perform other dangerous tasks. Don’t do so after taking Rexulti until you’re confident it doesn’t make you drowsy.

How to avoid Rexulti side effects

The best way to avoid side effects is to take Rexulti as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Rexulti that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Rexulti. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Rexulti as it can increase your risk of falling.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Rexulti.

7. Know the signs and symptoms of Rexulti side effects

Signs and symptoms of side effects include drowsiness and tiredness. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Rexulti may cause serious weight gain. If you experience this side effect while taking Rexulti, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Rexulti.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Rexulti as needed.

Kyleena side effects and how to avoid them

Kyleena is manufactured by Bayer. It is classed as a synthetic progestin hormone and is used for birth control. While Kyleena is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Kyleena include pelvic pain and ovarian cysts. Less common, but more serious side effects, can include life-threatening sepsis.

Learn more about the side effects of Kyleena and what you can do to avoid them.

What is Kyleena (levonorgestrel)?

There are two types of intrauterine devices available in the U.S. Copper IUDs (ParaGard) and hormonal IUDs (Mirena, Liletta, Skyla, and Kyleena). All of these devices are effective hormonal birth control methods. Kyleena is FDA-approved for birth control to prevent pregnancy for up to 3 to 6 years. Levonorgestrel is a synthetic progestin hormone and does not contain estrogen.

How exactly Kyleena and its release of levonorgestrel (LNG) within the uterus has a contraceptive effect is not fully understood. It is thought that Kyleena and similar LNG products have several methods of action. These include:

  • Thickening of the cervical mucus, which makes it more difficult for the sperm to pass into the uterus
  • Preventing sperm from maturing into sperm that are able to fertilize an egg
  • Making it more difficult for the sperm to survive in the uterus
  • To alter the lining of the uterus wall (endometrium)

Kyleena’s effects are completely reversible, and your fertility will rapidly return. You can become pregnant as soon as Kyleena is removed.

Kyleena dosage

Kyleena is a T-shaped plastic intrauterine device (IUD) inserted through the vagina and placed into the uterus. It will be inserted by a healthcare professional. The Kyleena hormonal IUD device releases levonorgestrel into the uterus, causing changes in your cervix and uterus. Kyleena may be used alone or with other medications. It is important to understand that Kyleena should not be used for emergency contraception. Your healthcare provider can help you decide which birth control options are best for you and if an IUD is right for you, and if so, which one is best for you. Kyleena does not protect against HIV or STIs (sexually transmitted infections).

This device can move out of place or come out by itself. If it comes out, contact your healthcare professional immediately for medical advice and use backup birth control such as condoms and spermicide to prevent pregnancy until you are advised otherwise.

Kyleena side effects

The most common side effects of Kyleena or adverse events include:

  • Pelvic pain
  • Ovarian cysts
  • Vulvovaginitis – inflammation or infection of the outer part of your vagina
  • Cramps or painful periods
  • Vaginal itching or infection
  • Missed, irregular menstrual periods (especially during the first 3 to 6 months), heavy bleeding, or changes in your bleeding patterns
  • Temporary pain, bleeding, or dizziness during IUD insertion
  • Stomach pain, nausea, vomiting, bloating
  • Migraine headaches
  • Depression, mood changes
  • Back pain
  • Breast pain or tenderness
  • Weight gain
  • Acne
  • Changes in hair growth
  • Loss of interest in sex
  • Puffiness in your face, hands, ankles, or feet

In rare instances, Kyleena can cause more serious side effects. These can include:

  • Severe infection or sepsis (a rare but life-threatening infection) can occur within the first few days
  • Pain during sexual intercourse
  • An ectopic pregnancy (pregnancy not in the uterus) – if this should occur remove the intrauterine system as leaving it in place can increase the risk of spontaneous abortion and preterm labor
  • Increased risk of intrauterine pregnancy
  • Perforation – the intrauterine device may go into the wall of the uterus or through the wall of the uterine cavity
  • Severe cramps or abdominal pain
  • Severely dizzy or lightheaded
  • Confusion, vision problems, sensitivity to light
  • Heavy vaginal bleeding, vaginal sores, unusual vaginal discharge
  • Pale skin, weakness, easily bruised or bleeding, fever, chills, or other signs of infection
  • Yellowing of the skin or eyes (jaundice)
  • Increased risk of blood clots, stroke, or heart attack. Symptoms may include sudden numbness or weakness, severe headache, or chest pain.

Your doctor will assess the benefits of using Kyleena against your risk of possible side effects. If you experience any of these serious side effects, stop taking Kyleena and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Kyleena drug interactions

Kyleena can interact with other medications which can affect your blood levels of levonorgestrel and make this form of birth control less effective. These include:

  • Antivirals – amprenavir, boceprevir, fosamprenavir, telaprevir
  • Anticancer treatment – brigatinib, dabrafenib, encorafenib, pexidartinib
  • Anticonvulsants – carbamazepine, phenobarbital, phenytoin, felbamate
  • Etretinate – for the treatment of severe psoriasis
  • St. Johns wort

This list is not exhaustive and other drugs may interact with Kyleena. Call your doctor for further medical advice. Before taking Kyleena, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Kyleena warnings & precautions

You should not use Kyleena if you:

  • Are allergic to the active ingredient levonorgestrel
  • Have had an allergic reaction to any of the other ingredients in Kyleena
  • Have abnormal vaginal bleeding
  • Have an untreated pelvic or genital infection
  • Have endometriosis or a serious pelvic infection called pelvic inflammatory disease (PID) after a pregnancy or abortion in the last 3 months
  • Have had PID in the past unless you have had a normal pregnancy after the infection went away
  • Have cervix, or uterine cancer
  • Have breast cancer or any other cancer sensitive to progestin, now or in the past
  • Have uterine fibroid tumors
  • Have liver problems such as liver disease or a liver tumor
  • Have a weak immune system due to conditions such as AIDS or leukemia
  • If you have another IUD device in place
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Kyleena if you:

  • Are taking any of the medications that could interact with Kyleena
  • Have or have ever had high blood pressure, heart problems, or a stroke
  • Have any bleeding problems
  • Suffer from migraines or headaches
  • Have a vaginal or pelvic infection, or have a sexually transmitted disease
  • Are breastfeeding or are planning to breastfeed – Kyleena is unlikely to affect the quality or amount of your breast milk or the health of your nursing baby. However, a small number of cases of a reduction in milk production have been reported

You should always check with your doctor or pharmacist before taking any medication, including Kyleena, to make sure it is safe for you.

Do I need to avoid alcohol with Kyleena?

Alcohol will not affect IUDs, implants, patches, the ring, or the effectiveness of the pill.

Is weight gain a side effect of Kyleena?

Kyleena can cause weight gain associated with water retention caused by progestin, rather than an increase in body fat percentage

Does Kyleena have emotional side effects?

Kyleena can cause depression and mood changes. Speak to your doctor for medical advice if you experience these side effects.

How long do Kyleena side effects last?

Side effects may last from a couple of weeks up to 6 months, depending on who you listen to or what you read. The general advice is to give the side effects time to pass. However, if you do have persistent troublesome side effects it is always best to speak to your healthcare provider.

What is the cost of Kyleena?

Kyleena prices without insurance will vary depending on where you buy it. As a guide, Kyleena intrauterine device 19.5 mg usually costs $1,050 for 1 device.

How to avoid Kyleena side effects

The best way to avoid side effects is to take Kyleena as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Kyleena that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Kyleena. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Kyleena.

6. Know the signs and symptoms of Kyleena side effects

Signs and symptoms of side effects include depression and changes in mood. If you experience any of these symptoms contact your doctor for medical advice.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Kyleena.

8. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Kyleena as needed.

Is Trulicity insulin?

Insulin is a hormone normally produced by your pancreas to help with glycemic control. If your pancreas doesn’t produce any insulin (Type 1 diabetes), or if your body is unable to use the insulin produced properly, (Type 2 diabetes) this can result in high blood glucose levels and serious problems for your health. Treatments for Type 2 diabetes either improve insulin secretion or improve the body’s use of the insulin produced.

Trulicity is a non-insulin medication used to treat people with Type 2 diabetes mellitus. In this article, we will take a closer look at what Trulicity is, how Trulicity works, how you take Trulicity, its side effects, and other useful information you should know when using it.

What is Trulicity?

Trulicity is the brand name for an FDA-approved diabetes medication manufactured by Eli Lilly and Company. It is used with diet and exercise to lower blood sugar levels in adults with type 2 diabetes. Trulicity contains dulaglutide as the active ingredient and belongs to a class of drugs known as GLP-1 receptor agonists (glucagon-like peptide 1).

RELATED: What is Trulicity

Is Trulicity the same as insulin?

Trulicity is not the same as insulin. Trulicity is the brand name for dulaglutide once-weekly injections.

What is Trulicity used for?

Trulicity is used in adults who have type 2 diabetes to:

  • Reduce high blood sugar levels, when used alongside exercise and diet changes
  • Reduce the risk of serious cardiovascular events, like strokes or heart attacks, in people with heart disease, or reduce the risk factors for heart problems. Examples of risk factors for an increased risk of cardiovascular disease include high cholesterol, being elderly, having high blood pressure, and smoking

Trulicity is not approved by the FDA for the treatment of type 1 diabetes, diabetic ketoacidosis, or weight loss. Currently, the only GLP-1 agonists approved for weight loss are Wegovy (semaglutide) and Saxenda (liraglutide).

How does Trulicity work?

If you have type 2 diabetes, you may not produce enough insulin, or you may even become resistant to insulin. If this happens, you will absorb less sugar from your blood, resulting in your blood glucose levels remaining too high.

The active ingredient dulaglutide in Trulicity is classed as a GLP-1 receptor agonist (glucagon-like peptide 1), which can lower your A1C levels. It is absorbed into your digestive system where it has two effects. It binds with areas on some of your cells called GLP1R receptors, This encourages your pancreas to make more insulin and allows other cells in your body to more effectively remove sugar from your blood. At the same time, dulaglutide also reduces how much sugar your pancreas secretes into your blood. The combination of these two processes can reduce your blood sugar levels.

What are the most commonly prescribed doses of Trulicity?

Trulicity is available in injection form, in the following doses: 0.75 mg/0.5 mL solution in a single-dose prefilled Trulicity pen, and 1.5 mg/0.5 mL solution in a single-dose prefilled Trulicity pen.

RELATED: Trulicity Doage

How do I take Trulicity?

Inject Trulicity as a subcutaneous injection in the abdomen, thigh, or upper arm as a weekly dose at any time of the day. Initiate treatment with Trulicity at 0.75 mg once weekly. Your dose of Trulicity can be increased to 1.5 mg once weekly for additional glycemic control.

If you miss a dose it should be taken as soon as you remember. If less than 3 days (72 hours) remain before your next scheduled dose, skip the missed dose and take your next dose on the regularly scheduled day.

Your healthcare provider may use Trulicity in combination with other diabetes medications such as metformin and empagliflozin. Please see the full drug information and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Trulicity?

The most common side effects of Trulicity in clinical trials compared to placebo include:

  • Injection-site reactions like swelling, pain, or itching
  • Nausea, vomiting
  • Gastrointestinal side effects include diarrhea, constipation, and abdominal pain
  • Reduced appetite

Do not take more Trulicity than recommended. Taking more than the recommended may lead to serious side effects. More serious side effects of Trulicity include:

  • Severe allergic reactions to the medication such as anaphylaxis or shortness of breath
  • Thyroid tumors and a type of thyroid cancer called medullary thyroid carcinoma
  • Inflammation of your pancreas (pancreatitis)
  • Kidney problems, including kidney failure
  • Increased heart rate
  • Hypoglycemia (low blood sugar) particularly when used with other medications like insulin or sulfonylurea
  • Severe stomach problems
  • Changes in your vision

If you do experience any serious side effects, stop taking Trulicity and seek medical attention immediately. You are encouraged to report negative adverse events of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

RELATED: Trulicity side effects and how to avoid them

What type of insulin is Trulicity?

Trulicity is not an insulin of any type. Trulicity belongs to a class of drugs called antidiabetics, glucagon-like peptide-1 agonists (GLP-1 agonists). Other GLP-1 agonist drugs include Ozempic (semaglutide), Byetta (exenatide), Bydureon Bcise (exenatide), and Victoza (liraglutide).

Does Trulicity replace insulin?

Trulicity does not replace insulin in people with diabetes whose pancreas does not produce insulin. Dulaglutide, the active ingredient in Trulicity works by stimulating insulin secretion from your pancreas. Trulicity is only used in people with Type 2 diabetes. Insulin is used to treat people with Type 1 or Type 2 diabetes.

How is Trulicity different from insulin?

Dulaglutide, the active ingredient in Trulicity works by stimulating insulin secretion from your pancreas and is only used in people with Type 2 diabetes. Insulin is used to treat people with Type 1 or Type 2 diabetes.

Is it possible to take too much Trulicity?

Yes, if you take too much Trulicity, your blood sugar level could drop to a low level causing hypoglycemia. Contact your healthcare provider immediately for medical advice if this should happen.

How does Trulicity work for weight loss?

Trulicity is designed to act in a similar manner to glucagon-like peptide 1 (GLP-1) in the body. Trulicity can be taken at any time of day, with or without food. Trulicity slows gastric emptying, which helps to reduce your appetite by making you feel fuller for longer.

RELATED: Trulicity for weight loss: does it work?

How long do you stay on Trulicity for?

You may need to take Trulicity for up to 5 weeks before you start to see it lower blood glucose levels. Full effects of Trulicity may not be seen for at least 3 to 6 months.

What are the dangers of taking Trulicity?

Trulicity can cause common side effects such as nausea, vomiting, diarrhea, abdominal pain, indigestion, and fatigue. It can also cause more serious side effects such as hypoglycemia and serious allergic reactions. It is also important to bear in mind that Trulicity may affect other medical conditions you have, such as kidney disease, thyroid tumors, and inflammation of your pancreas. Speak to your doctor for medical advice before initiating treatment with Trulicity.

What is the difference between Trulicity and other diabetes medications?

There are a vast array of medications for diabetes belonging to different classes of drug. Short and rapid-acting insulins (Humalog), biguanides (metformin), DPP-4 inhibitors (sitagliptin), and sulfonylureas (Glynase) are to name but a few. These are available as injections, liquids, and tablets for oral use. Trulicity is available in injection form for subcutaneous use. Speak to your doctor for medical advice as to which treatment is the best option for you.

RE:ATED: Trulicity vs metformin, Mounjaro vs Trulicity, Rybelsus vs Trulicity, Ozempic vs Trulicity

Can you take Trulicity and insulin together?

You may be at a higher risk of hypoglycemia or severe hypoglycemia if you take Trulicity with an insulin secretagogue (eg, sulfonylurea). Your healthcare provider will monitor you closely for this side effect.

Which medications can be taken with Trulicity?

Drug interactions may occur with Trulicity, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your healthcare provider about all of your medications including any supplements you are taking.

What warnings are there with Trulicity?

Discuss your medical history with your doctor before starting treatment with Trulicity, as treatment with Trulicity may have contraindications.

  • Trulicity may cause new or worsening kidney disease, including kidney failure. Be careful to not become dehydrated while using Trulicity as this could also cause kidney problems
  • You may have an allergic reaction to Trulicity. You will have to stop treatment if you have allergic reactions to Trulicity or any of its other ingredients. Tell your doctor if you have previously had an allergic reaction to medications such as Ozempic which belongs to the same class of drugs as Trulicity
  • Trulicity may make a condition known as diabetic retinopathy worse. Make sure you monitor yourself for any changes in your vision
  • Acute and chronic pancreatitis (inflammation of the pancreas) have been reported in clinical studies. Report any symptoms of pancreatitis, including persistent severe stomach pain which sometimes radiates to the back
  • Your risk of hypoglycemia (low blood sugar) is increased if Trulicity is used in combination with an insulin secretagogue (sulfonylurea) or insulin. Your dosage of other treatments may need to be adjusted
  • Trulicity may cause thyroid C-cell tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC). See the boxed warning for Trulicity and speak to your healthcare provider if you get swelling in your neck, hoarseness, difficulty swallowing, or shortness of breath. Tell your doctor if you have a family history of MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2
  • Tell your doctor if you are pregnant or breastfeeding. Trulicity shouldn’t be used during pregnancy and for at least two months before a planned pregnancy because it is not known if it may affect your unborn child

What is the difference between Trulicity and Victoza?

Trulicity (dulaglutide) or Victoza (liraglutide) are both possible treatment options if you have type 2 diabetes. They both belong to the same drug class, glucagon-like peptide-1 (GLP-1) agonists. They also are both given via an injection under the skin. Trulicity is given as a weekly injection while Victoza is injected once a day.

They are both used to help manage blood sugar levels in adults with type 2 diabetes and lower the risk of cardiovascular events in people with type 2 diabetes and heart disease. Victoza can also be used to manage blood sugar levels in children 10 years and older with type 2 diabetes.

RELATED: Victoza vs Trulicity

Medical Malpractice Uncovered

Which states have filed the most medical malpractice suits and what are the total costs?

Being involved in a serious and potentially fatal injury can be incredibly traumatic to a person’s mental wellbeing as well as their physical health. Now, imagine the ongoing stress and further suffering after receiving the incorrect treatment. Medical negligence is when an individual receives substandard care provided by a medical professional that has caused injury or caused an existing condition to worsen.

There are many ways that medical malpractice can occur, including misdiagnosis, poorly given treatment, or surgical mistakes. Unfortunately, it happens more commonly than you may think, and even in majorly developing cities that offer medical care for celebrities and the super-rich.

One of the most common cases of medical malpractice is when patients are prescribed the incorrect medication.

Right here in the US, many medical professionals have had to fork out millions of dollars to pay for medical malpractice reports filed by patients. It’s often the biggest threat facing doctors today, and it is a hugely debatable topic, because of the rising cost of medicine in the US. Some states were more prominent in just how many doctors were sued, and some lawsuits were a lot more costly to settle than others.

At NiceRx, we decided to explore which states have filed the most medical malpractice suits, and which have paid out the most against these suits. By looking at medical data over the last 10 years, we were able to explore this concept with a focus on modern-day medical malpractice.

The States That Filed the Most Medical Malpractice Reports

By delving into health data, we found that the states with the most medical malpractice reports filed in the last 10 years were geographically diverse. By considering each state’s population size, we were able to get an accurate result for the number of malpractice reports. Here are the states with the most medical malpractice reports:

Top 5 states that filed the most medical malpractice reports

 

1. New York

Reports Filed per 10,000 Residents: 19.03

The state of New York saw the highest number of lawsuits filed against doctors, nurses and healthcare professionals between 2012 and 2022. The state filed 15,951 medical malpractice reports over the 10-year period, a total of 19.03 reports per 10,000 residents.

All states have very specific deadlines for filing lawsuits, and in New York, a lawsuit for medical malpractice usually must be filed within two years and six months, but there are some instances which extend the standard lawsuit-filing deadline, for example, when the patient could not reasonably have learned that they had a viable medical malpractice case. In New York, the discovery rule is more limited than it is in other states.

2. Georgia

Reports Filed per 10,000 Residents: 8.06

Georgia has the second-highest number of medical malpractice reports between 2012 and 2022. Georgia residents filed 2,994 lawsuits for medical negligence during the 10-year period, a total of 8.06 reports per 10,000 residents.

The general statute of limitations for medical malpractice lawsuits in Georgia is two years. There are exceptions to the rule, however, that can affect the time a patient has to file his or her claim.

3. New Jersey

Reports Filed per 10,000 Residents: 6.84

New Jersey was the third highest state for its number of medical malpractice reports over the 10-year period, with a total of 6,078 reports filed by patients, a total of 6.84 reports per 10,000 residents.

New Jersey courts use what’s known as the “discovery rule” in medical malpractice cases. Under this rule, the filing deadline is two years after you discovered, or could reasonably have been expected to discover, that a doctor or other health care provider could be responsible for your harm.

The states that filed the most medical malpractice reports

 

The States That Filed the Least Medical Malpractice Reports

These states filed the least reports in the last 10 years, which does not necessarily mean that medical malpractice is a less common occurrence for these states. The laws regarding malpractice could be more complex and winning a lawsuit could be a lengthier process.

 

Top 5 states that filed the least medical malpractice reports

 

1. Wisconsin

Reports Filed per 10,000 Residents: 1.01

The state of Wisconsin has the lowest score for its medical malpractice lawsuits between 2012 and 2022, with just 588 reports filed during this time, a total of 1.01 reports filed per 10,000 residents. Wisconsin has a specific statute of limitations that states a patient injured by medical negligence has three years after the alleged negligence happened, to file a lawsuit in court.

2. Minnesota

Reports Filed per 10,000 Residents: 1.15

Minnesota had the second lowest score for its medical malpractice reports filed between 2012 and 2022, with 643 lawsuits counted during this period, a total of 1.15 reports filed per 10,000 residents.

In Minnesota, the standard deadline for filing a claim is four years from the date of the medical error. There is currently no cap on medical malpractice damages in Minnesota (including on compensation for things like pain and suffering), so an injured patient is free to recover for all financial losses that can be attributed to the defendant’s malpractice.

3. North Dakota

Reports Filed per 10,000 Residents: 1.32

North Dakota had the third lowest score for its medical malpractice reports filed during the year 10-year period, with 100 lawsuits filed during this period, a total of 1.32 reports filed per 10,000 residents.

North Dakota places a cap on the amount of compensation that is available to a plaintiff who has been successful in a medical malpractice lawsuit. There is a $500,000 cap on noneconomic damages in medical malpractice cases, which include compensation for things like pain and suffering, emotional distress, and the loss of enjoyment of life that result from the defendant’s medical malpractice.

The states that filed the least medical malpractice reports

 

The States with the Most Costly Medical Malpractice Reports

Now, we will move on to the US states with the priciest lawsuits filed against medical professionals for medical malpractice. We were able to find each state’s total costs during the period of 2012 – 2022.

 

Top 5 states with the most costly medical malpractice reports

 

1. Ohio

Total Cost of Medical Malpractice Lawsuits ($M): $853,310,000.00

The state of Ohio saw the most expensive lawsuits out of all the US states during the 10-year period. The total cost of medical malpractice lawsuits in Ohio cost the medical industry over $853.3 million. Ohio has damage caps on medical malpractice lawsuits for non-economic injuries. These caps are; $250,000 per plaintiff or three times the economic damages, whichever is higher, and the maximum is $350,000 per patient and $500,000 per occurrence.

If a patient’s injuries are found to be “catastrophic” the damage limit is set at $500,000 per individual and $1 million per occurrence. The five most common medical malpractice cases are misdiagnosis, drug errors, delayed care, surgical mistakes and failure to obtain consent.

2. Connecticut

Total Cost of Medical Malpractice Lawsuits ($M): $798,350,000.00

Connecticut has the second most expensive lawsuits for medical malpractice in the US, with a total of $798.35 million over the 10-year period.

Connecticut doesn’t currently have a cap on the economic or non-economic damages that victims of medical malpractice can seek from lawsuits and injury claims. In some cases, punitive damages can also be awarded.

3. Arizona

Total Cost of Medical Malpractice Lawsuits ($M): $724,960,000.00

Arizona is the state with the third most expensive lawsuits for medical malpractice in the US, with almost $725 million between 2012 and 2022.

Arizona does not place a cap on the amount of damages recoverable in a medical malpractice action. An article of the Arizona Constitution prohibits the enactment of any law limiting the damages one may recover for personal injury or death.

States with the most costly medical malpractice reports

The States with the Least Costly Medical Malpractice Reports

We will now explore the US states with the least pricey lawsuits filed against medical professionals for medical malpractice.

 

Top 5 states with the least costly medical malpractice reports

 

1. Maryland

Total Cost of Medical Malpractice Lawsuits ($M): $1,008,002.00

Maryland had the lowest cost of medical malpractice lawsuits between 2012 and 2022, with a total cost of $1.08 million. Maryland has enacted malpractice caps, setting a ceiling on the amount of money that can be recovered in a case. In Maryland,the laws on the licensing of physicians, physician assistants, nurses and other medical professionals do not require the purchase of medical professional liability insurance.

2. Texas

Total Cost of Medical Malpractice Lawsuits ($M): $1,052,210.00

Texas saw the second lowest medical malpractice lawsuits during the 10-year period, with the total cost amounting to $1.052 million. In Texas, malpractice payments are capped at $250,000 in cases against a single hospital or doctor and $500,000 in cases involving multiple defendants.

3. Georgia

Total Cost of Medical Malpractice Lawsuits ($M): $1,281,450.00

Georgia had the third lowest costs for medical malpractice cases between 2012 and 2022, with the total costs accounting for $1.28 million. In Georgia, there is a $350,000 cap in place on non-economic damages in any single medical malpractice claim against health care providers.

States with the least costly medical malpractice reports

Methodology 

We started by looking at the U.S. Department of Health & Human Services’ Data Analysis Tool to generate a data set for medical malpractice payment reports. To make the data more relevant to modern-day practice, we filtered the results from 2012 to 2022.

We were able to collect the reports for each state, and the total amounts of malpractice payments made by healthcare providers during the ten-year period. This data is accurate as of 06/10/2022.

We collected each state’s population size and were able to calculate the number of reports filed by the population, to get a more accurate representation of the number of medical malpractice reports. This data is accurate as of 19/10/2022.

We were able to rank each state by the total number of medical malpractice reports by population and the total costs of payments, to find the top-scoring states for both factors.

How long does Ozempic stay in your system?

Type 2 diabetes affects over 6% of the population, causing people suffering from this condition to be more susceptible to other health risk factors such as kidney and heart disease.

Ozempic is still a relatively new treatment for diabetes, but its use is growing fast with more people across the world using it every day. In this article, we will answer questions commonly asked about Ozempic, such as what is Ozempic, how does Ozempic work, how long will Ozempic stay in your system, what are Ozempic’s long-term effects and side effects, and other useful information to know when using Ozempic.

What is Ozempic?

Ozempic is the brand name for a diabetes medication used with diet and exercise to treat type 2 diabetes in adults. Ozempic contains semaglutide as the active ingredient. It belongs to a class of drugs known as GLP-1 receptor agonists (glucagon-like peptide 1) and is used to improve blood sugar control.

What is Ozempic used for?

Ozempic is a prescription drug manufactured by Novo Nordisk. It is approved by the US Food and Drug Administration (FDA) to:

  • Lower blood sugar levels in combination with diet and exercise in patients with type 2 diabetes. It has not been studied in patients with pancreatitis and it is not indicated for use in type 1 diabetes mellitus or diabetic ketoacidosis
  • To reduce the risk of major adverse cardiovascular events (heart attack and stroke) in adults with type 2 diabetes mellitus and established heart disease
  • Ozempic is also the first FDA-approved medication for use in patients with obesity even if they do not have type 2 diabetes

How does Ozempic work?

Semaglutide, the active ingredient in Ozempic binds and activates GLP-1 receptors, helping to lower your blood glucose levels by stimulating insulin secretion from your pancreas and reducing glucagon secretion. So when your blood glucose level is high, your body will release more insulin and less glucagon. Ozempic also slightly delays the time it takes your food to empty out of your stomach immediately after eating (gastric emptying), reducing the rate at which glucose enters into your bloodstream.

How long does it take for Ozempic to work?

Ozempic will produce results immediately. The full effects however will take between 4 to 5 weeks as it will take time to raise semaglutide levels to a steady state.

How long does it take for Ozempic to suppress appetite?

Ozempic is normally taken 1 to 2 hours after breakfast in the morning. This will help to suppress your appetite during the day. Ozempic will also slow gastric emptying. This will help to reduce your appetite by making you feel fuller for longer.

Do you regain weight after stopping Ozempic?

Studies have shown that patients who lost the most weight during treatment with Ozempic gained the most weight after stopping. The weight regained was often less than the weight lost during treatment.

How long does it take for Ozempic to get into your system?

Your blood sugar levels will start to fall within the first week of treatment. Full effects of Ozempic may take up to 8 weeks or longer.

How long does Ozempic stay in your system?

Ozempic has a half-life of about 1 week, meaning it takes 1 week for half of the Ozempic in your body to leave your system. It will take about 5 weeks for Ozempic to be completely cleared from your system. You will not be able to flush Ozempic from your system faster.

How long does it take for the effects of Ozempic to wear off?

It could take up to 5 weeks for Ozempic to clear from your system. You may however continue to see effects and potentially serious side effects for some time after. You should contact your doctor for medical advice if you continue to have side effects.

When should I stop Ozempic?

You should stop using Ozempic and seek medical attention immediately if you have a serious allergic reaction. Symptoms may include swelling of your face, lips, tongue, or throat, difficulty breathing, a severe rash or itching, dizziness, or a faster-than-normal heartbeat.

What happens if you stop using Ozempic?

Ozempic does not cause withdrawal symptoms, but your blood sugar levels will increase if you stop using Ozempic suddenly. Consult your healthcare provider if you are considering stopping taking Ozempic.

What are the side effects of Ozempic?

The most common side effects of Ozempic compared to placebo include:

  • Injection site reactions
  • Nausea
  • Vomiting
  • Gastrointestinal side effects – diarrhea, abdominal pain, and constipation
  • Weight loss

Serious side effects include:

  • Increased risk of thyroid cancer
  • Pancreatitis
  • Diabetic retinopathy complications
  • Hypoglycemia when used with insulin secretagogues or insulin
  • Acute kidney injury
  • Gallbladder disease
  • Allergic reactions – symptoms include hives, dizziness, fast heartbeats, trouble breathing, and swelling of your face, lips, tongue, or throat

How long does nausea last?

A common side-effect of Ozempic is mild to moderate gastrointestinal disturbances, including nausea. These symptoms will normally pass after a few weeks of using Ozempic.

How long do Ozempic side effects last?

These side effects may continue for up to 5 weeks after Ozempic has been discontinued. Your doctor will assess the benefits of using Ozempic against your risk of side effects. You are encouraged to report side effects or adverse events of Ozempic to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Does Ozempic have long-term effects?

Discuss your medical history with your doctor before starting treatment with Ozempic, as treatment with Ozempic may worsen certain conditions.

  • Ozempic may cause new or worsening kidney disease, including kidney failure. Be careful to not become dehydrated while using Ozempic as this could also cause kidney problems
  • You may have an allergic reaction to Ozempic. You will have to stop treatment if you have allergic reactions to Ozempic or any of its other ingredients. Tell your doctor if you have previously had an allergic reaction to medications such as Trulicity which belongs to the same class of drugs as Ozempic
  • Ozempic may make a condition known as diabetic retinopathy worse. Make sure you monitor yourself for any changes in your vision
  • Acute and chronic pancreatitis (inflammation of the pancreas) have been reported in clinical studies. Report any symptoms of pancreatitis, including persistent severe stomach pain which sometimes radiates to the back
  • Your risk of hypoglycemia (low blood sugar) is increased if Ozempic is used in combination with an insulin secretagogue (sulfonylurea) or insulin. Your dosage of other treatments may need to be adjusted
  • Ozempic may cause thyroid C-cell tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC). See the boxed warning for Ozempic and speak to your healthcare provider if you get swelling in your neck, hoarseness, difficulty swallowing, or shortness of breath. Tell your doctor if you have a family history of MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2
  • Tell your doctor if you are pregnant or breastfeeding. Ozempic shouldn’t be used during pregnancy and for at least two months before a planned pregnancy because it is not known if it may affect your unborn child

What are the risks of long-term use of Ozempic?

You may continue to experience serious side effects, such as diabetic retinopathy after Ozempic has been cleared from your system. Talk to your healthcare provider for medical advice.

How do I take Ozempic?

  • Use Ozempic injections exactly as your healthcare provider prescribes it. Inject Ozempic under the skin as a subcutaneous injection into your stomach, thigh, or upper arm
  • Use Ozempic at any time of the day on the same day each week. You may change the day of the week you take this medication as long as your last dose was given 2 or more days before
  • If you miss a dose of Ozempic, take the missed dose as soon as you remember if it’s within 5 days of the missed dose. If more than 5 days have passed, skip the missed dose and take your next dose on the regularly scheduled day
  • Take Ozempic with or without food
  • Don’t mix insulin and Ozempic in the same injection. You may inject them both in the same area but not right next to each other
  • Rotate injection sites with each injection
  • Stay on your diet and exercise program while on Ozempic.
  • Discuss how to prevent, recognize and manage low blood sugar (hypoglycemia), and high blood sugar (hyperglycemia) with your healthcare professional
  • Do not share your Ozempic pen with other people to reduce your risk of infection
  • Store Ozempic in the refrigerator before its first use. After its first use, you can store it at a controlled room temperature or refrigerate it for 56 days. Keep the pen cap on when not in use. Ozempic should be stored away from heat, direct sunlight, and moisture
  • Your doctor may prescribe Ozempic to be used in addition to other diabetes medications, such as metformin or insulin

Other drugs may interact with Ozempic, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your healthcare provider about all of your medications including any supplements you are taking.

Is Ozempic insulin?

Insulin is a hormone normally produced by your pancreas to help with glycemic control. If your pancreas doesn’t produce any insulin (Type 1 diabetes), or if your body is unable to use the insulin produced properly, (Type 2 diabetes) this can result in high blood glucose levels and serious problems for your health. Treatments for Type 2 diabetes either improve insulin secretion or improve the body’s use of the insulin produced.

Ozempic is a non-insulin medication used to treat people with Type 2 diabetes mellitus. In this article, we will take a closer look at what Ozempic is, how Ozempic works, how you take Ozempic, its side effects and other useful information you should know when using it.

What is Ozempic (semaglutide)?

Ozempic is the brand name for a diabetes medication used with diet and exercise to treat type 2 diabetes in adults. Ozempic contains semaglutide as the active ingredient. It belongs to a class of drugs known as GLP-1 receptor agonists (glucagon-like peptide 1) and is used to improve blood sugar control.

RELATED: What is Ozempic

What type of insulin is Ozempic?

Ozempic is not an insulin of any type. Ozempic belongs to a class of drugs called antidiabetics, glucagon-like peptide-1 agonists (GLP-1 agonists). Other GLP-1 agonist drugs include Trulicity (dulaglutide), Byetta (exenatide), Bydureon (exenatide) and Victoza (liraglutide).

Is Ozempic the same as insulin?

Ozempic is not the same as insulin. Ozempic is the brand name for semaglutide once-weekly injections. Ozempic is also available as an oral medication version with the same active ingredient, semaglutide, under the brand name Rybelsus.

RELATED: Rybelsus for weight loss: does it work?

What is the difference between Ozempic and insulin?

Ozempic is classified as a GLP-1 agonist drug which is different than insulin. GLP-1 drugs contain a small protein that is similar to insulin (called a peptide). As proteins are easily broken down by stomach acids, which results in making the protein inactive, both Ozempic and insulin need to be injected under the skin to enable the drug to enter the body and bypass the gut.

How do GLP-1 antagonist drugs work and what is the mechanism of action?

GLP-1 acts in several different ways that help improve control of blood sugar levels, these include:

  • Stimulating the pancreas to release insulin. If your blood glucose level is already low, insulin is not released by the pancreas, preventing GLP-1 drugs from causing hypoglycaemia.
  • Reducing the production of glucose by your liver. Normally, the liver would release glucose when your blood glucose levels are low and store glucose when blood glucose levels are high. In Type 2 diabetes, this process does not function as it should. Instead the liver continuously produces glucose causing high blood glucose levels.
  • GLP-1 slows the rate of gastric emptying (the movement of food from your stomach into your small intestines). This causes you to feel full quicker and helps to reduce your appetite. Because the rate of movement is slowed, the rate at which nutrients (such as glucose) are absorbed into your blood stream is also slowed. This may have a combined effect of reducing your food intake.

What is Ozempic used for?

Ozempic is a prescription drug manufactured by Novo Nordisk. It is approved by the US Food and Drug Administration (FDA) to:

  • Lower blood sugar levels in combination with diet and exercise in patients with type 2 diabetes. It has not been studied in patients with pancreatitis and it is not indicated for use in type 1 diabetes mellitus or diabetic ketoacidosis
  • To reduce the risk of major adverse cardiovascular events (heart attack and stroke) in adults with type 2 diabetes mellitus and established heart disease
  • Ozempic is also the first FDA-approved medication for use in patients with obesity even if they do not have type 2 diabetes

How does Ozempic work?

Semaglutide, the active ingredient in Ozempic binds and activates GLP-1 receptors, helping to lower your blood glucose levels by stimulating insulin secretion from your pancreas and reducing glucagon secretion. So when your blood glucose level is high, your body will release more insulin and less glucagon. Ozempic also slightly delays the time it takes your food to empty out of your stomach immediately after eating (gastric emptying), reducing the rate at which glucose enters into your bloodstream.

What are the most commonly prescribed doses of Ozempic?

Ozempic is available in injection form, in the following doses: 2mg/1.5ml pre-filled pen (delivering doses of 0.25 mg or 0.5 mg per injection), 4mg/3ml pre-filled pen (delivering 1mg per injection), and 8mg/3ml pre-filled pens (delivering 2mg per injection).

RELATED: Ozempic dosage

How do I take Ozempic?

  • Use Ozempic injections exactly as your healthcare provider prescribes it. Inject Ozempic under the skin as a subcutaneous injection into your stomach, thigh, or upper arm
  • Use Ozempic at any time of the day on the same day each week. You may change the day of the week you take this medication as long as your last dose was given 2 or more days before
  • If you miss a dose of Ozempic, take the missed dose as soon as you remember if it’s within 5 days of the missed dose. If more than 5 days have passed, skip the missed dose and take your next dose on the regularly scheduled day
  • Take Ozempic with or without food
  • Don’t mix insulin and Ozempic in the same injection. You may inject them both in the same area but not right next to each other
  • Rotate injection sites with each injection
  • Stay on your diet and exercise program while on Ozempic.
  • Discuss how to prevent, recognize and manage low blood sugar (hypoglycemia), and high blood sugar (hyperglycemia) with your healthcare professional
  • Do not share your Ozempic pen with other people to reduce your risk of infection
  • Store this medication in the refrigerator before its first use. After its first use, you can store it at a controlled room temperature or refrigerate it for 56 days. Keep the pen cap on when not in use. Ozempic should be stored away from heat, direct sunlight, and moisture
  • Your doctor may prescribe Ozempic to be used in addition to other diabetes medications, such as metformin or insulin

Other drugs may interact with Ozempic, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. You should read the full prescribing information and the medication guide provided with this medication and tell your healthcare provider about all of your medications including any supplements you are taking.

What are the side effects of Ozempic?

The most common side effects of Ozempic compared to placebo in clinical trials include:

  • Injection site reactions
  • Nausea
  • Vomiting
  • Gastrointestinal side effects – diarrhea, abdominal pain, and constipation
  • Weight loss

Serious side effects include:

  • Increased risk of thyroid cancer
  • Pancreatitis
  • Diabetic retinopathy complications
  • Hypoglycemia when used with insulin secretagogues or insulin
  • Acute kidney injury
  • Gallbladder disease
  • Allergic reactions – symptoms include hives, dizziness, fast heartbeats, trouble breathing, and swelling of your face, lips, tongue, or throat

RELATED: Ozempic side effects and how to avoid them

Does Ozempic replace insulin?

Ozempic does not replace insulin in people with diabetes whose pancreas does not produce insulin. Semaglutide, the active ingredient in Ozempic works by stimulating insulin secretion from your pancreas. Ozempic is only used in people with Type 2 diabetes. Insulin is used to treat people with Type 1 or Type 2 diabetes.

What is the difference between basal insulin and bolus insulin?

Basal insulin is longer-acting insulin that helps to maintain steady glucose levels. Bolus insulin is shorter-acting insulin most often taken before meals. Your treatment with insulin is normally a combination of both shorter and longer-acting insulins.

Is it possible to take too much Ozempic?

Yes, if you take too much Ozempic, your blood sugar level could drop to a low level causing hypoglycemia. Contact your healthcare provider immediately for medical advice if this should happen.

RELATED: What happens if you take too much Ozempic?

How does Ozempic work for weight loss?

Ozempic is designed to act in a similar manner to glucagon-like peptide 1 (GLP-1) in the body. Ozempic is taken 1 to 2 hours after breakfast in the morning which will help to suppress your appetite during the day. Ozempic also slows gastric emptying. This will help to reduce your appetite by making you feel fuller for longer.

RELATED: Ozempic for weight loss

How long do you stay on Ozempic for?

Your starting dose of Ozempic will be 0.25 mg weekly for 4 weeks. This will be increased to 0.5 mg once weekly for a further 4 weeks. If your blood sugar levels are under control you will continue taking 0.5 mg once a week.

Is Ozempic a stimulant?

Ozempic is not a stimulant.

What is the difference between Ozempic and RHI?

RHI stands for short-acting insulin. Insulin is injected at least once a day. Ozempic is a long-acting treatment with a dose of Ozempic given once weekly, and is not considered an RHI.

How do I know if I need to take Ozempic?

Ozempic is used in adults with type 2 diabetes who also have risk factors such as cardiovascular disease or are at high risk of developing cardiovascular disease, kidney disease, or heart failure. Speak to your doctor if you have symptoms of type 2 diabetes such as feeling tired, hunger, frequent urination, increased thirst, problems with your vision, slow wound healing, or yeast infections.

Are there any foods or medications you should avoid while on Ozempic?

While there are no foods you need to specifically avoid while taking Ozempic, you are advised to monitor what you eat and drink and to avoid foods high in fat, sugar, or high in calories.

RELATED: What foods to avoid while taking Ozempic

Can you take Ozempic and insulin together?

You may be at a higher risk of hypoglycemia or severe hypoglycemia if you take Ozempic with an insulin secretagogue (eg, sulfonylurea). Your healthcare provider will monitor you closely for this side effect.

Which medications can be taken with Ozempic?

Your doctor may prescribe Ozempic to be used in addition to other diabetes medications, such as metformin or insulin.

What warnings are there with Ozempic?

  • Ozempic may cause new or worsening kidney disease, including kidney failure. Be careful to not become dehydrated while using Ozempic as this could also cause kidney problems
  • You may have an allergic reaction to Ozempic. You will have to stop treatment if you have allergic reactions to Ozempic or any of its other ingredients. Tell your doctor if you have previously had an allergic reaction to medications such as Trulicity (dulaglutide) which belongs to the same class of drugs as Ozempic
  • Ozempic may make a condition known as diabetic retinopathy worse. Make sure you monitor yourself for any changes in your vision
  • Acute and chronic pancreatitis (inflammation of the pancreas) have been reported in clinical studies. Report any symptoms of pancreatitis, including persistent severe stomach pain which sometimes radiates to the back
  • Your risk of hypoglycemia (low blood sugar) is increased if Ozempic is used in combination with an insulin secretagogue (sulfonylurea) or insulin. Your dosage of other treatments may need to be adjusted
  • Ozempic may cause thyroid C-cell tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC). See the boxed warning for Ozempic and speak to your healthcare provider if you get swelling in your neck, hoarseness, difficulty swallowing, or shortness of breath. Tell your doctor if you have a family history of MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2
  • Tell your doctor if you are pregnant or breastfeeding. Ozempic shouldn’t be used during pregnancy and for at least two months before a planned pregnancy because it is not known if it may affect your unborn child

Is Ozempic better than Victoza?

Ozempic (semaglutide) or Victoza (liraglutide) are both possible treatment options if you have type 2 diabetes. They both belong to the same drug class, glucagon-like peptide-1 (GLP-1) agonists. They also are both given via an injection under the skin. Ozempic is given as a weekly injection while Victoza is injected once a day.

They are both used to help manage blood sugar levels in adults with type 2 diabetes and lower the risk of cardiovascular events in people with type 2 diabetes and heart disease. Victoza can also be used to manage blood sugar levels in children 10 years and older with type 2 diabetes.

RELATED: Ozempic vs Victoza

What is the difference between Ozempic and Wegovy?

While they are both the same generic semaglutide, Ozempic is used to treat type 2 diabetes and Wegovy is used with diet and exercise for chronic weight management in overweight adults who also have at least one weight-related medical condition such as type 2 diabetes, high blood pressure, or high cholesterol.

RELATED: Wegovy vs Ozempic

What foods to avoid while taking Brilinta

Brilinta contains ticagrelor a blood thinner that reduces your risk for cardiovascular problems such as heart attacks (myocardial infarction) or stroke, by preventing the formation of blood clots that cause them. While there are no specific foods (other than grapefruit juice) that are strictly prohibited while taking Brilinta, it is recommended to avoid certain foods including those high in fat, sugar, and calories.

Here we will discuss what Brilinta is, how it works, what its side effects are, its drug interactions, and what foods you should avoid and what foods you may consume safely.

What is Brilinta?

Brilinta is an FDA-approved medication manufactured by AstraZeneca. It is used to reduce the risk of heart attacks, strokes, and death from heart disease caused by blood clots blocking blood vessels. It’s prescribed to adults who:

  • Have previously had a heart attack
  • Have coronary artery disease (CAD) and are at a high risk of having a heart attack or a stroke
  • Have acute coronary syndrome (ACS), which occurs when blood flow to the heart is suddenly blocked
  • Have ACS and who have been treated with a stent

Brilinta is available in tablet form, in the following doses: 60 mg and 90 mg tablets. Your loading and maintenance dose of Brilinta is based on the condition you are being treated for. Take Brilinta with a daily dose of aspirin of 75-100 mg. The combination of aspirin and an inhibitor such as Brilinta is called dual antiplatelet therapy (DAPT).

You are advised to read the drug information and medication guide provided with this medicine and to speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Brilinta?

The most common side effects of Brilinta in clinical trials include:

  • An increased risk of minor bleeding, including nosebleeds and bruising
  • Shortness of breath
  • Dizziness
  • Nausea

More serious side effects of Brilinta include:

  • Slow heart rhythm
  • Serious bleeding such as serious internal and external bleeding that could potentially be fatal
  • Life-threatening allergic reactions that could cause swelling in your face, mouth, or throat, heart palpitations, or problems breathing

If you experience any of these serious side effects, stop taking Brilinta and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Brilinta drug interactions

Brilinta can interact with other medications. These include:

  • Any medications taken to treat heart conditions such as high blood pressure
  • Statins for the treatment of high cholesterol – simvastatin
  • Any blood thinners – clopidogrel, heparin, warfarin
  • Digoxin
  • Pain killers – codeine, ibuprofen
  • Antibiotics – erythromycin
  • Medications taken to treat HIV/AIDS
  • Antifungal medicines taken orally – ketoconazole
  • Any anti-seizure medications – carbamazepine, phenytoin

Other drugs may interact with Brilinta, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your healthcare professional about all of your medications including any supplements you are taking.

Brilinta contraindications

You should not use Brilinta if you:

  • Are allergic to the active ingredient ticagrelor, or to any of the other ingredients in Brilinta
  • Have ever had bleeding in your brain
  • Are currently bleeding

Talk to your doctor about your medical condition before using Brilinta if you:

  • Have ever had a stroke
  • Have ever had stomach ulcers or colon polyps
  • Have any liver problems
  • Have asthma or chronic obstructive pulmonary disease (COPD)
  • Have recently had surgery or a serious injury
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

What foods should I avoid while taking Brilinta?

You must not drink grapefruit juice while taking this medication. Grapefruit juice can block one of the enzymes your body uses to break down Brilinta in the body. Grapefruit juice may increase the effects of Brilinta and increase your risk of bleeding. Speak to your doctor for medical advice.

What are the best foods to eat while taking Brilinta?

There are no specific foods that you need to eat while taking Brilinta. However, it is generally recommended to eat a healthy diet low in fat, sugar, and calories to prevent high blood sugar.

Unlike other anticoagulants, such as warfarin, you can eat green leafy vegetables such as spinach, kale, and broccoli, or other food rich in vitamin K-rich.

Brilinta can be taken with or without food. Food will not affect how well Brilinta works or how much is absorbed into your body.

How does Brilinta work?

The active ingredient in Brilinta, ticagrelor, inhibits platelet activation by binding to receptors on the surface of your platelets. This stops them from being able to stick together preventing the process that causes clotting.

Who can take Brilinta?

Brilinta can be used in adults who have previously had a heart attack, have coronary artery disease (CAD) and are at a high risk of having a heart attack or a stroke, have acute coronary syndrome (ACS), which occurs when blood flow to the heart is suddenly blocked, or adults who have ACS and who have been treated with a stent.

What should I know about Brilinta vs. Plavix?

Both Brilinta and Plavix are used to reduce the risk of severe events such as heart attack and stroke.

Both drugs are classed as antiplatelets and both may cause similar side effects, such as an increased risk for bleeding.

There are differences between these medications. Plavix is taken once daily, and Brilinta is taken twice daily. They also have different drug interactions. Brilinta contains ticagrelor as the active ingredient, Plavix contains clopidogrel.

RELATED: Brilinta vs Plavix

What foods to avoid with pancreatitis

Acute pancreatitis is a condition caused by inflammation of the pancreas over a short period of time. Most people will recover from acute pancreatitis within a week and have no further complications, but some people may develop serious complications. Acute pancreatitis is not the same as chronic pancreatitis, where the pancreas is damaged permanently from years of inflammation.

Acute pancreatitis is often associated with gallstones and consuming too much alcohol. By reducing your alcohol intake and making changes to your diet, you can reduce your risk of developing acute pancreatitis. Here we will look at what pancreatitis is, its symptoms, which foods you should avoid, as well as what foods you can eat, and treatments available to improve your quality of life.

Symptoms of acute pancreatitis

The most common symptom of acute pancreatitis is severe pain suddenly developing in the center of your stomach. Other symptoms include:

  • Nausea, vomiting
  • Indigestion
  • Abdominal pain
  • Fever
  • Yellowing of the whites of your eyes and skin (jaundice)
  • Tenderness or swelling of the tummy
  • Increased heart rate or breathing

Eating or drinking may make your symptoms worse especially if you eat fatty foods. Acute pancreatitis caused by gallstones normally occurs after eating a large meal. Pain caused by alcohol develops 6 to 12 hours after drinking excessively.

Benefits of a Pancreatitis Diet

A pancreas not working properly may not be able to produce insulin, leading to diabetes. Studies show that high-fat diets are more likely to cause abdominal pain in males and more likely to cause chronic pancreatitis at a younger age.

Reducing fat intake helps the pancreas to repair and prevents further damage. Patients with severe chronic pancreatitis have been seen to benefit from having a low-fat diet.

A pancreatitis diet plan will be based on your individual dietary needs. Fat is a vital part of a balanced diet, and you will need to adjust the type of fat you eat. A fat called medium-chain triglycerides (MCTs) can be digested without you pancreas being involved. Also, you may be prescribed digestive enzymes if you are unable to process certain fats. These enzymes can replace what your pancreas would normally, but can not produce. Examples of pancreatic enzyme therapy includes Pancreaze and Creon.

The most common causes of pancreatitis are due to alcohol abuse or gallstones (crystallized cholesterol stones that form in the gallbladder) that block enzymes needed from leaving the pancreas. A pancreatitis diet can also help you reduce malnutrition. Vitamins A, D, and E are fat-soluble, and problems with fat digestion can make it more difficult to absorb these nutrients,

Foods to avoid

You may need to manage your diet based on if you are having an acute attack or are trying to stop inflammation. If you are having an acute attack, you may need to stick to softer, more bland, low-fat foods until your symptoms stop. To stop future attacks you may need to make changes to your diet, using diet tips provided.

The general principle for any diet plan is to eat a healthy balanced diet. Foods to avoid that trigger attacks and cause flare-ups include:

  • Refined carbohydrates – white bread, sugary foods and drinks, cakes, cookies, waffles, granola, cereal, and pastries
  • Red meat, organ meat
  • Processed meat (sausage, hot dogs, lunchmeat)
  • Mayonnaise, margarine, butter, nut butter (peanut, almond), full-fat dairy, whole milk, cheese
  • Ice cream, custards, milkshakes, smoothies with dairy
  • Alcohol
  • Baked goods – donuts, bagels, croissants
  • Battered/fried fish and shellfish
  • Eggs with yolk
  • Fried foods/fast food – stir-fried vegetables, fried rice, fried eggs, french fries, potato chips
  • Jams, jellies
  • Soda, energy drinks

What foods can I eat?

The best foods you can eat include:

  • Vegetables
  • Fruits
  • Whole grains
  • Beans, lentils
  • Low-fat or nonfat dairy
  • Antioxidant-rich foods – dark, leafy vegetables, blueberries, sweet potatoes, grapes, walnuts, and pomegranates (avocado, olive oil, fatty fish, nuts, and seeds in moderation)
  • Dairy-free alternatives (almond, rice)
  • Fish (haddock, cod)
  • Sugar-free fruit and vegetable juice
  • Decaffeinated coffee, or herbal tea
  • Lean meats
  • Low or non-fat dairy products
  • Low-fat sweets – graham crackers, ginger snaps, tea biscuits
  • Nutritional supplement drinks
  • Poultry without the skin – chicken, turkey
  • Low-sugar jams and jellies
  • Low-fat or fat-free clear soups and broth
  • Spices and fresh herbs – salsa, tomato-based sauces
  • Sugar-free gelatin, ice pops
  • Tuna in water

Treatment for pancreatitis

If gallstones are causing your pancreatitis, you may require an endoscopic retrograde cholangiopancreatogram to remove the gallstones or the removal of your gallbladder. If alcohol was the cause of your acute pancreatitis you should completely avoid alcohol once you have recovered.

In some cases, medication such as amitriptyline (Elavil), gabapentin, or pregabalin may be used to help relieve the pain. Discuss what the most effective treatment option is for you with your healthcare provider.

Eating small meals and snacks throughout the day instead of larger meals may also help with the symptoms of pancreatitis.

Take multivitamins and supplements to replace any nutrients you cannot get in your food. Speak with a registered dietitian or nutritionist about which supplements are suitable for you. Also, speak to your nutritionist to develop a healthy eating plan and to discuss other lifestyle changes you can make to manage your condition better without putting too much stress on your digestive system.

Lovenox side effects and how to avoid them

Lovenox is a brand-name medication manufactured by Sanofi-aventis. It is classed as an anticoagulant and is used to treat heart disease. While Lovenox is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Lovenox include pain at the injection site. Less common, but more serious side effects, can include severe allergic reactions.

Learn more about the side effects of Lovenox and what you can do to avoid them.

What is Lovenox (enoxaparin)?

Lovenox (enoxaparin sodium) is a blood thinner that blocks certain proteins from forming blood clots. This helps reduce the risk of complications such as heart attacks or strokes. Lovenox is FDA-approved to treat the following conditions:

  • Acute coronary syndromes such as ST-elevation myocardial infarction (STEMI), Non-ST elevation myocardial infarction, and unstable angina
  • Prophylaxis of blood vessel complications of unstable angina (chest pain) and non–Q-wave myocardial infarction (MI)
  • Deep vein thrombosis (DVT) prophylaxis in abdominal surgery, hip replacement surgery, knee replacement surgery, or bedridden patients
  • Pulmonary embolism (PE)
  • Prevention and treatment of venous thromboembolism (VTE)
  • Treatment for prosthetic valve thrombosis in pregnancy
  • Percutaneous coronary intervention (PCI)

The active ingredient in Lovenox is called enoxaparin sodium. It is a low molecular weight heparin that helps to treat blood clots or prevent them from happening by disrupting the clotting process. A complex chemical process causes your blood to clot. One step of this process is controlled by an enzyme called clotting factor Xa. Enoxaparin sodium stops your blood from clotting by deactivating clotting factor Xa. It stimulates a protein that’s already in your blood, called antithrombin, to attach to clotting factor Xa, stopping it from working. This disrupts the clotting process and makes it harder for your blood to form clots.

Lovenox dosage

Lovenox is available in injection form, in the following doses: Prefilled syringes: 30 mg/0.3 mL, and 40 mg/0.4 mL, Graduated prefilled syringes: 60 mg/0.6 mL, 80 mg/0.8 mL, and 100 mg/1 mL, Multiple-dose vials: 300 mg/3 mL, and 150 mg/mL, Graduated prefilled syringes: 120 mg/0.8 mL, and 150 mg/1 mL.

You take Lovenox by injecting it under your skin (subcutaneously), using a pre-filled syringe. Be sure to rotate your injection site with each daily dose. Lovenox has a half-life of up to 7 hours, and its anticoagulant effects last up to 12 hours. Due to this and its predictable effects, Lovenox does not need extensive monitoring or supervision.

If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and use your next dose at the normally scheduled time.

Use a Lovenox needle and syringe once and then place in a sharps container, following your local or state laws on how to dispose of your sharps container.

Store Lovenox at room temperature between 15°C-30°C. Discard any unused Lovenox from the multiple-dose vials 28 days after the first use. Store Lovenox in a cool, well-ventilated, dry place away from direct sunlight.

You are advised to read the medication guide provided with this medicine for the full drug information and patient information and to speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Lovenox side effects

The most common side effects of Lovenox in clinical trials include:

  • Bleeding gums, nose bleeds, and vaginal bleeding
  • Swelling (edema)
  • Pain at the site of injection
  • Nausea
  • Diarrhea
  • Fever
  • Anemia
  • A discoloration of your skin caused by bleeding or bruising under it (ecchymosis)
  • Shortness of breath, trouble breathing
  • Confusion
  • A low blood platelet count (thrombocytopenia) – may show up in blood tests
  • A high level of the enzyme aminotransferase in your blood – may show up in blood tests

More serious side effects of Lovenox include:

  • Severe allergic reactions to the medication
  • An increased risk of major bleeding events, like hemorrhage (bleeding from a ruptured blood vessel)
  • Epidural catheter or spinal hematomas (bleeding and accumulation of blood in your spine). These can be caused by medications like Lovenox in medical patients who receive a spinal puncture or local anesthetic injections around their spine – this could result in permanent paralysis

Contact your healthcare provider for medical advice about any side effects you experience while taking Lovenox. You can report your side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Lovenox drug interactions

When Lovenox is taken with other medicines, they may interact and change how they work. They can also change the frequency and severity of side effects. Make sure your doctor is aware of all prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take. Some major drug interactions with Lovenox include:

  • Blood thinners or anticoagulants such as warfarin, clopidogrel, rivaroxaban and dipyridamole
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen
  • Herbal supplements such as ginkgo biloba, fish oil, and garlic

Lovenox warnings & precautions

You should not use Lovenox if you:

  • Are allergic to enoxaparin sodium or any of the other ingredients in Lovenox
  • Are allergic to any other heparin, or other low molecular weight heparins such as nadroparin, tinzaparin, or dalteparin
  • Are allergic to any pork products
  • Are allergic to benzyl alcohol
  • Are bleeding heavily, or have a condition with a high risk of bleeding
  • Have ever had a reaction called heparin-induced thrombocytopenia which causes a severe drop in platelets
  • Are under 18 years of age

Talk to your doctor before taking Lovenox if you:

  • Are taking any of the medications that could interact with Lovenox
  • Have a susceptibility to bleeding
  • Have previously had any bleeding problems
  • Have a prosthetic heart valve
  • Have uncontrolled high blood pressure
  • Have a history of stomach ulcers (gastrointestinal ulceration)
  • Have diabetes
  • Have had eye damage caused by a complication of diabetes (diabetic retinopathy)
  • Have severe kidney disease
  • Have severe liver problems
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age
  • Are going to have an operation that involves a lumbar puncture or local anesthetic injections in and around your spine

You should always check with your doctor or pharmacist before taking any medication, including Lovenox, to make sure it is safe for you.

How to avoid Lovenox side effects

The best way to avoid side effects is to take Lovenox as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Lovenox that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Lovenox. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Lovenox as it can increase your risk of bleeding.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Lovenox.

7. Know the signs and symptoms of Lovenox side effects

Signs and symptoms of side effects include nausea, diarrhea, and fever. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Lovenox does not cause weight gain or weight loss. If you experience changes in your weight while taking Lovenox, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Lovenox.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Lovenox as needed.

What foods to avoid with IBS

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder affecting 10% of the population in the United States each year. Symptoms of IBS include cramping, diarrhea, flatulence, and bloating.

Here we will look at what irritable bowel syndrome is, its symptoms, which food triggers IBS and so to avoid, as well as what foods you can eat, and treatments available to improve your quality of life.

What is IBS?

IBS is thought to be caused by a problem in how your gut and brain work together causing your digestive tract to be very sensitive. This causes abdominal pain, diarrhea, and constipation. IBS is classified depending on your type of bowel movement problems.

  • IBS with constipation (IBS-C)
  • IBS with diarrhea (IBS-D)
  • IBS with mixed bowel habits (IBS-M)

What kind of IBS you have will determine what treatment will work best for you.

Symptoms of IBS

Symptoms of IBS will vary for each individual, depending on the type of IBS you have. General symptoms will include:

  • Abdominal pain
  • Bloating
  • Cramping
  • Diarrhea
  • Constipation
  • Flatulence
  • Passing mucus
  • Feeling tired
  • Nausea
  • Backache
  • Difficulty urinating
  • Bowel incontinence

Medication for IBS

Medications given to you by your doctor will be based on the type of IBS you have and your symptoms. Examples of medications for IBS include:

  • Lotronex – relaxes your colon and slows the passage of waste through your lower bowel. Lotronex is for severe cases of IBS-D in women who haven’t responded well enough to other treatments
  • Viberzi – reduces diarrhea by decreasing muscle contractions and fluid secretion in the intestine
  • Xifaxan – decreases bacterial overgrowth and diarrhea
  • Amitiza, Linzess – increases the secretion of fluid in your small intestine to help with the passage of stools in women with IBS-C who haven’t responded to other treatments

Discuss what the most effective treatment option is for you with your healthcare provider.

Foods to avoid

The general principle for any diet plan is to eat a healthy balanced diet. Foods to avoid that trigger attacks and cause flare-ups include:

  • Food containing lactose such as dairy products. These include cow’s milk, yogurt, ice cream, and cheese. Chocolate and candy can also trigger IBS as they contain fat, lactose, and caffeine
  • Fruits – apples, pears, cherries, mangoes, watermelon, and dried fruit
  • Honey, agave nectar, high fructose corn syrup
  • Artificial sweeteners such as sorbitol, mannitol, xylitol, maltitol, and isomalt found in sugar-free gum and mints
  • Cruciferous vegetables – artichokes, asparagus, brussels sprouts, cabbage, garlic, and onions
  • Grains such as wheat and rye
  • Legumes – chickpeas, lentils, kidney beans, and soy products
  • Insoluble fiber – bran, whole grains, nuts, and the skins of fruits and vegetables
  • Starches common in partially baked bread, and processed foods such as potato chips
  • Fried food

What foods can I eat?

Foods you can eat include:

  • Lactose-free milk, almond milk, coconut milk
  • Lactose-free yogurt
  • Hard cheeses such as feta and brie
  • Yogurt containing probiotics
  • Soluble fiber found in beans, fruits, and oat products helps to regulate bowel movements
  • Bananas, blueberries, grapefruit, kiwi, lemon, oranges, and strawberries
  • Vegetables such as bean sprouts, carrots, cucumbers, eggplant, ginger, lettuce, potatoes, spring onions, and turnips
  • Food containing protein – beef, pork, chicken, fish, and eggs
  • Nuts – almonds, peanuts, pine nuts, and walnuts
  • Gluten-free pasta
  • Corn flour, and quinoa
  • Whole grains like rice and oats, but not whole-wheat flour like bread, pasta, and cereal
  • Low-FODMAP vegetables – green beans, spinach, squash, and sweet potatoes

IBS diet plans

A handy tip is to keep a food journal to help identify the foods that are your triggers. Essentially those foods that bring about an attack. Your food journal should allow you to make decisions about which foods you should or should not eat. Useful information to include in your journal would be:

  • The foods you have eaten
  • The date and time
  • What reactions you have had
  • When you had flare-ups or worsening symptoms
  • Any stressful events or periods of anxiety that bring about flare-ups

Food journals are useful when you’re looking to add certain foods to your diet. Add one food at a time and record your symptoms. This way you can see if a certain food is suitable or not.

Your diet plan should include:

  • Foods to eat and avoid
  • How to modify foods rather than avoiding them completely. Peeling or cooking a fruit or vegetable might make all the difference and may mean you do not miss out on essential nutrients needed for a healthy balanced diet
  • Supplements you can take to replace any nutrients you cannot get in your food. Speak with a registered dietitian or nutritionist about which supplements are suitable for you
  • Meal plans – these will help you to stick to foods that do not make your symptoms worse
  • Any advice given to you by your doctor or dietitian

Your symptoms of IBS may change over time, so it is important to keep a track of these changes. Record and review changes in your diet and speak to your healthcare provider if flare-ups become worse or occur more often than usual.

Premade diet plans such as the low FODMAP diet are available and can be beneficial. However, as mentioned before, we are all different, and what works for me may not work for you. Speak to your nutritionist or a registered dietitian to develop a healthy eating plan and to discuss other lifestyle changes you can make to manage your condition better.

What is the low FODMAP diet?

FODMAP stands for Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols. These are fermentable, short-chain carbohydrates.

  • Oligosaccharides – fructans and galacto-oligosaccharides (GOS)
  • Disaccharides – lactose
  • Monosaccharides – fructose
  • Polyols – sorbitol and mannitol

It has been found that foods classed as FODMAPs are not absorbed well in the small intestine. They have been found to increase the amount of fluid in the bowel and make you gassier. This leads to bloating, pain, and diarrhea.

It has been shown that a low FODMAP diet will help improve IBS symptoms with studies showing that over 70% of patients following the low FODMAP diet had some improvement, and those who continued to eat high-FODMAP foods were more likely have flare-ups.

Speak to a registered dietician to make sure you have a safe and healthy eating plan, and to discuss other lifestyle changes you can make to improve your quality of life.

Enbrel side effects and how to avoid them

Enbrel is an FDA-approved medication manufactured by Amgen. It is classed as a biologic and used to treat autoimmune diseases. While Enbrel is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Enbrel include injection site reactions and upper respiratory infections. Less common, but more serious side effects, can include new or worsening heart failure, and multiple sclerosis.

Learn more about the side effects of Enbrel and what you can do to avoid them.

What is Enbrel (etanercept)?

Enbrel contains the active ingredient etanercept. It is approved by the US Food & Drug Administration to treat the following autoimmune diseases:

  • Moderate to severe chronic plaque psoriasis
  • Psoriatic arthritis with or without methotrexate
  • Moderate to severe rheumatoid arthritis with or without methotrexate
  • Ankylosing spondylitis (inflammation of joints in the spine).
  • Moderate to severe polyarticular juvenile idiopathic arthritis (joint pain and inflammation in children and adolescents with more than 4 joints affected)

Inflammation is a vital part of your immune system’s response to infection. It signals to your body to defend itself and that repair is needed. However, inflammation in healthy tissue, especially if it persists, can cause damage. Rheumatoid arthritis is caused by chronic inflammation in your joints, while ankylosing spondylitis is caused by chronic inflammation in your spine.

Enbrel helps treat autoimmune conditions by reducing inflammation. This helps to ease the symptoms of these diseases and limits the damage they can cause. Your immune system normally triggers inflammation by releasing a signaling molecule called TNF-alpha. This molecule attaches itself to areas inside your cells, beginning the process that causes inflammation. The active ingredient etanercept stops this from happening. It attaches itself to TNF-alpha molecules, stopping them from working. This halts the inflammation process before it’s even started.

Enbrel dosage

Enbrel is available as:

  • 50 mg single-use prefilled syringe with 0.98 mL of a 50 mg/mL solution of etanercept
  • 50 mg single-use prefilled SureClick Autoinjector with 0.98 mL of a 50 mg/mL solution of etanercept
  • 25 mg single-use prefilled syringe with 0.51 mL of a 50 mg/mL solution of etanercept
  • 25 mg multiple-use vial with 25 mg of etanercept

You are given Enbrel as a subcutaneous injection using either a pre-filled syringe or an injectable pen. It is important to use a new needle each time to prevent the risk of infection. You may get injection site reactions such as redness, bruising, or irritation after administration, but this will settle down after a few hours.

You are advised to read the medication guide provided with this medicine for the drug information and patient information and to speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Enbrel side effects

The most common side effects of Enbrel include:

  • Urinary tract infections
  • Skin infections
  • Injection site reactions
  • Upper respiratory infections, sinusitis, and influenza
  • Sore throat
  • Headache

Enbrel can cause more serious side effects, including:

  • Inflammation of the blood vessels
  • Suppression of the immune system
  • Increased risk of cancer, particularly lymphoma
  • New or worsening heart failure
  • New or worsening psoriasis
  • Allergic reactions – swelling of your face, lips, tongue, or arms, itchiness and hives
  • Serious infections
  • Autoimmune hepatitis
  • Multiple sclerosis or Guillain-Barré syndrome
  • Pancytopenia (decreased levels of certain blood cells)
  • Inflammatory bowel disease, such as ulcerative colitis
  • Lupus-like syndrome – joint pain or swelling, feeling short of breath, skin rash on your cheeks or arms

Your doctor will test your blood to make sure you don’t have hepatitis B virus before you receive Enbrel, as this treatment can reactivate your infection.

If you experience any of these serious side effects, stop taking Enbrel and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Enbrel drug interactions

Enbrel can interact with other medications including:

  • Anakinra
  • Abatacept
  • Sulfasalazine
  • Live vaccines
  • Cyclophosphamide
  • Other immunosuppressants

Other medical conditions may affect your treatment with Enbrel so you should always seek medical advice from the healthcare professional prescribing your drugs.

Enbrel warnings & precautions

Don’t take Enbrel if you:

  • Are allergic to the active ingredient etanercept
  • Are allergic to any of the other ingredients in Enbrel
  • Are at risk of developing a serious blood infection called sepsis
  • If you have any kind of active infection

Talk to your physician before taking Enbrel if you:

  • Have a history of recurring infections
  • Have a history of congestive heart failure
  • Have ever had cancer, such as lymphoma
  • Have diabetes
  • Have ever had tuberculosis, or have been in close contact with someone who has had tuberculosis
  • Have ever had Hepatitis B or Hepatitis C
  • Have nervous system problems such as multiple sclerosis
  • Have optic neuritis (inflammation of the nerves in the eyes)
  • Have transverse myelitis (inflammation of the spinal cord)
  • Have blood disorders such as leukemia or anemia
  • Suffer from seizures
  • Are allergic to latex
  • Are under 18 years of age (Enbrel is suitable for children, but varying age limits are recommended for different autoimmune diseases)
  • Have been around someone with chicken pox
  • Are pregnant, planning to become pregnant
  • Are breastfeeding or planning to breastfeed – this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Enbrel, to make sure it is safe for you.

Other warnings you should know about

Serious infections and reactivation of infections have occurred in patients taking Enbrel. Infections include tuberculosis as well as fungal infections and infections caused by viruses or bacteria. Your healthcare provider should test you for tuberculosis before starting treatment and continue to monitor you closely before, during, and after treatment.

Unusual cancers have been reported in children and teenage patients using tumor necrosis factor (TNF) blockers before 18 years of age. Children, teenagers, and adults taking TNF blockers such as Enbrel are at an increased risk of developing lymphoma (fever, night sweats, weight loss, stomach pain or swelling, and swollen glands) and melanoma or non-melanoma skin cancers.

How to avoid Enbrel side effects

The best way to avoid side effects is to take Enbrel as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Enbrel that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Enbrel. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Drinking alcohol in excess can lead to alcoholic hepatitis. People with alcoholic hepatitis are at a higher risk of death from using Enbrel.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Enbrel.

7. Know the signs and symptoms of Enbrel side effects

Signs and symptoms of side effects include infections, and injection site reactions. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

If you have unexplained weight loss, it could be a sign of a serious infection with hepatitis B or tuberculosis caused by Enbrel. Speak to your doctor for medical advice if you experience any changes in weight.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Enbrel.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Enbrel as needed.

Jemperli side effects and how to avoid them

Jemperli is an FDA-approved brand name medication manufactured by GlaxoSmithKline (GSK). It is classed as a cancer treatment. While Jemperli is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Jemperli include fatigue and muscle weakness. Less common, but more serious side effects, can include liver problems and allergic reactions.

Learn more about the side effects of Jemperli and what you can do to avoid them.

What is Jemperli (dostarlimab)?

Jemperli contains the active ingredient dostarlimab-gxly, a programmed death receptor-1 inhibitor IgG4 humanized monoclonal antibody approved for:

  • The treatment of adults with advanced endometrial cancer or mismatch repair deficient (dMMR) recurrent, as determined by the results of an FDA-approved test, that has progressed or following prior treatment with a platinum-containing regimen, or
  • Advanced solid tumors, as determined by the results of an FDA-approved test, that have progressed on or following prior treatment and who have no satisfactory alternative treatment options

Jemperli works by binding to the PD-1 receptor blocking its interaction with the PD-1 ligands PD-L1 and PD-L2.

The indications follow an FDA review and are determined by the results from the dMMR endometrial cancer cohort A1 and the dMMR solid-tumor (non-endometrial cancer) cohort F of the ongoing GARNET trial. The GARNET study represents the largest dataset of anti-PD-1 monotherapy treatment of women with endometrial cancer.

Jemperli dosage

Jemperli is available in injection form, in the following doses: 500 mg/10 mL (50 mg/mL) solution in a single-dose vial.

Doses 1 to 4 are 500 mg taken every 3 weeks. Subsequent dosing is taken 3 weeks after Dose 4. Dose 5 onwards is 1,000 mg taken every 6 weeks. Jemperli is administered as an intravenous infusion taken over 30 minutes. Patients are treated until unacceptable toxicity or disease progression.

You are advised to read the medication guide provided with this medicine for the drug information and patient information and to speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Jemperli side effects

The most common side effects of Jemperli in clinical trials include:

  • Tiredness, muscle weakness, and muscle pain
  • Anemia (low red blood cells)
  • Diarrhea, constipation
  • Nausea
  • Laboratory abnormalities – decreased lymphocytes,  decreased sodium, decreased albumin, increased alkaline phosphatase, increased transaminases
  • Acute kidney injury or other kidney problems
  • Adrenal Insufficiency

In rare instances, Jemperli can cause more serious side effects. These can include:

  • Immune system problems – pneumonitis, colitis, hepatitis, nephritis with renal dysfunction, immune-mediated dermatologic reactions, and organ transplant rejection. Evaluate liver enzymes, creatinine, and thyroid function regularly during treatment. Withhold or permanently stop treatment and give corticosteroids depending on the severity of the reaction
  • Liver problems – upper right-sided stomach pain, loss of appetite, bruising or bleeding, dark urine, black tarry stools, jaundice (yellowing of the eyes or skin)
  • Pneumonitis – new or worsening cough, chest pain, or shortness of breath
  • Infusion-related reactions
  • Urinary tract infection
  • Abdominal pain
  • Inflammation of the brain and nervous system
  • Serious and fatal complications can occur in patients who receive allogeneic HSCT before or after being treated with a PD-1/PDL1–blocking antibody
  • Allergic reactions – hives, difficulty breathing, swelling in your face or throat that could be life-threatening
  • Hormonal disorder – unusual headaches, dizziness, feeling very weak, changes in behavior or mood, increased hunger or thirst, hoarse voice,  increased urination, hair loss, constipation, feeling cold,  sweating, weight gain or weight loss
  • Skin problems – rash, itching, fever or flu-like symptoms, swollen lymph nodes, blisters, peeling, or skin sores, painful sores or ulcers in your nose, mouth, throat, or genital area

Your doctor will assess the benefits of using Jemperli against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Jemperli to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Jemperli drug interactions

There is currently no data for Jemperli interactions with other medications. However, other medications may affect dostarlimab-gxly, including prescription drugs, vitamins, over-the-counter medicines, and herbal products.

Jemperli warnings & precautions

You should not use Jemperli  if you:

  • Are allergic to the active ingredient dostarlimab-gxly
  • Are allergic to any of the other ingredients in Jemperli
  • Are pregnant or are planning to become pregnant – Use effective contraception during treatment and for 4 months after your last dose
  • Are breastfeeding or are planning to breastfeed – do not breastfeed during treatment and for 4 months after your last dose

Talk to your doctor before using Jemperli  if you:

  • Are taking any of the medications that could interact with Jemperli

You should always check with your doctor or pharmacist before taking any medication, including Jemperli, to make sure it is safe for you.

How to avoid Jemperli side effects

The best way to avoid side effects is to take Jemperli as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Jemperli that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Jemperli. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Jemperli as it can increase your risk of dehydration and worsen side effects such as diarrhea.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Jemperli.

7. Know the signs and symptoms of Jemperli side effects

Signs and symptoms of side effects include liver and kidney problems. If you experience any of the side effects above speak to your doctor for medical advice.

8. Monitor your weight

Jemperli may cause weight loss or weight gain. If you experience this side effect while taking Jemperli, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Jemperli.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Jemperli as needed.

Symbicort side effects and how to avoid them

Symbicort is a brand-name medication manufactured by AstraZeneca. It is used for the treatment of chronic obstructive pulmonary disease. While Symbicort is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Symbicort include sore throats. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Symbicort and what you can do to avoid them.

What is Symbicort (budesonide/formoterol)?

Symbicort (budesonide/formoterol) is an FDA-approved medication manufactured by AstraZeneca used to treat asthma in adults and children aged 12 and over. It is also used to improve symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema in adults.

Asthma is an inflammatory disease of the lungs and airways; it can cause your chest to tighten and make it difficult to breathe. COPD is a condition that also affects the lungs and makes it hard to breathe. Symbicort assists with both of these conditions by reducing inflammation and by relaxing the muscles in the lungs and airways. This helps to reduce the feeling of tightness in your chest and makes it easier for you to breathe.

Symbicort contains two active ingredients: budesonide and formoterol fumarate dihydrate. Formoterol fumarate dihydrate is a long-acting beta-agonist (LABA), and a bronchodilator, and relaxes the muscles in your airways, making it easier to breathe. Budesonide is an inhaled corticosteroid (ICS) that reduces inflammation in the lungs. When both are used in combination, they reduce the incidence of asthma symptoms and can help manage the symptoms of chronic obstructive pulmonary disease.

RELATED: What is Symbicort

Symbicort dosage

Symbicort is available as a metered-dose inhaler in the following doses: 80 mcg/4.5 mcg per actuation, 160 mcg/4.5 mcg per actuation.

Symbicort comes as a dry powder that is inhaled using an inhaler device called a Turbohaler. You usually take the medicine once a day to prevent symptoms from occurring. It can be taken as a preventative measure before an activity that causes you breathing problems.

Symbicort is not a rescue treatment for asthma attacks or bronchospasm. Use only fast-acting inhalation medicine for an asthma attack. Seek medical attention if your breathing problems get worse, or if you think your medications are not working.

Rinse your mouth with water after each use of your Symbicort inhaler. This will reduce the chances of developing sore throats or oral thrush. If you miss a dose, skip the missed dose and take your next dose at the normally scheduled time. Do not double your doses.

Store your Symbicort Turbuhaler at room temperature in an upright position, with the mouthpiece down. Keep away from heat or an open flame. Discard the canister once the counter reads 0 (zero), or if you have been using this particular Turbohaler for longer than 3 months.

Read the medication guide provided with this medicine for the full drug information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: Symbicort dosage

Symbicort side effects

The most common side effects of Symbicort in clinical trials include:

  • Mild sore throat and coughing
  • Throat irritation
  • Thrush (fungal infections)
  • Nasal congestion
  • Inflammation of the sinuses (sinusitis)
  • Upper respiratory tract infections
  • Back pain
  • Headaches
  • Stomach discomfort
  • Trembling and shaking
  • Pneumonia

More serious side effects of Symbicort include:

  • Disturbed sleep
  • Dizziness
  • Nausea
  • Unusual tiredness or weakness
  • Muscle cramps
  • Blurred vision
  • Immune system problem (eg, Churg-Strauss syndrome)
  • Increased risk of bone loss (osteoporosis)
  • High blood sugar (hyperglycemia) – symptoms include increased thirst or urination
  • Decreases in blood potassium levels (hypokalemia)
  • Worsening of breathing problems
  • Serious side effects, including chest pain, fast/slow/irregular heartbeat, severe dizziness, fainting, seizures
  • Serious allergic reactions such as hives, difficulty breathing, shortness of breath, swelling of your face, lips, tongue, or throat

If you experience any of these serious side effects, stop taking Symbicort and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Symbicort drug interactions

Symbicort can interact with other medications including:

  • Other medications to treat asthma or other breathing problems
  • Beta-blockers
  • Medications for a fast or uneven heartbeat
  • Medications to treat heart failure, like digoxin
  • Diuretics
  • Steroids taken orally
  • Tricyclic antidepressants
  • HIV-protease inhibitors
  • Medications for thyroid problems
  • Medications to treat Parkinson’s disease

Before taking Symbicort, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Symbicort warnings & precautions

You should not use Symbicort if you:

  • Are allergic to the active ingredients budesonide or formoterol fumarate dihydrate
  • Have had an allergic reaction to any of the other ingredients found in Symbicort
  • Are under 12 years of age (for treating asthma)
  • Are under 18 years of age (for treating chronic obstructive pulmonary disease)

Talk to your doctor before using Symbicort if you:

  • Are diabetic
  • Have a lung infection
  • Have severe liver problems
  • Have high blood pressure
  • Have or have had any heart problems, like narrowing of the arteries, an uneven heartbeat, or heart failure
  • Have glaucoma, cataracts, or other vision problems
  • Have been exposed to infections such as chicken pox or measles
  • Have problems with your adrenal glands or thyroid
  • Have low levels of potassium in your blood
  • Have an intolerance to any sugars
  • Are pregnant or are breastfeeding – budesonide passes into breast milk. It is not known if formoterol passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Symbicort, to make sure it is safe for you.

How to avoid Symbicort side effects

The best way to avoid side effects is to take Symbicort as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Symbicort that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Symbicort. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Avoid alcohol

Moderate drinking is advised while taking Symbicort as its effectiveness may be decreased and side effects may be increased.

4. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

5. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Symbicort.

6. Know the signs and symptoms of Symbicort side effects

Signs and symptoms of side effects include sore throats, oral thrush, and upper respiratory infections. If you experience any of these symptoms speak to your doctor for medical advice.

7. Monitor your weight

Weight gain has not been reported when using Symbicort. However, corticosteroids can cause weight gain. If you experience changes in your weight while taking Symbicort, get medical advice from your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Symbicort.

9. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Symbicort as needed.

Ajovy side effects and how to avoid them

Ajovy is a brand-name medication manufactured by Teva Pharmaceuticals. It is classed as a monoclonal antibody and is used for migraine prevention. While Ajovy is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Ajovy include injection site reactions. Less common, but more serious side effects, can include allergic reactions.

Learn more about the side effects of Ajovy and what you can do to avoid them.

What is Ajovy (fremanezumab-vfrm)?

Ajovy (fremanezumab) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Teva Pharmaceuticals USA, Inc. It is a calcitonin gene-related peptide (CGRP) antagonist used for the preventive treatment of migraine (episodic migraine or chronic migraine) in adults. Ajovy can help to lower the number of migraine headache days you have each month by 1.5 to 2 days per month. Ajovy works by binding to the calcitonin gene-related peptide (CGRP) ligand preventing it from binding to its receptor.

Ajovy dosage

Ajovy is available in injection form, in the following doses: Ajovy 225 mg/1.5 mL solution in a single-dose autoinjector prefilled syringe.

Ajovy is for subcutaneous injection use only. Two dosing options are available, 225 mg monthly, or 675 mg every 3 months. You should inject each dose of Ajovy into a new area of the skin. Ajovy injections can be given into your abdomen, thighs, or upper arms. When using Ajovy take it out of the refrigerator and let it reach room temperature for 30 minutes before injecting.

Read the full prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Ajovy side effects

The most common side effects of Ajovy in clinical trials compared to placebo include:

  • Injection site reactions such as injection site pain, induration, pruritus, and erythema

In rare instances, Ajovy can cause more serious side effects. These can include:

  • Hypersensitivity reactions

Get emergency medical help if you have signs of a serious allergic reaction, such as hives, trouble breathing, or swelling of your face, lips, tongue, or throat.

Your doctor will assess the benefits of using Ajovy against your risk of adverse effects. Patients are encouraged to report negative side effects or adverse reactions of Ajovy to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ajovy drug interactions

Other drugs may interact with Ajovy, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your healthcare provider about all of your medication including any supplements you are taking.

Ajovy warnings & contraindications

You should not use Ajovy if you:

  • Are allergic to the active ingredient fremanezumab-vfrm
  • Have had an allergic reaction to any of the other ingredients in Ajovy
  • Are younger than 18 years old

Talk to your doctor before using Ajovy if you:

  • Are taking any of the medications that could interact with Ajovy
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is unknown if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Ajovy, to make sure it is safe for you.

How to avoid Ajovy side effects

The best way to avoid side effects is to take Ajovy as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Ajovy that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Ajovy. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Dehydration is not a side effect of Ajovy. However, dehydration will make your symptoms of migraine worse so make sure you drink plenty of water to prevent this complication.

4. Avoid alcohol

Ajovy is not known to interact with alcohol. However, drinking alcohol can trigger a migraine attack in some people. Avoid alcohol while using Ajovy if it is a trigger for you.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Ajovy.

7. Know the signs and symptoms of Ajovy side effects

Signs and symptoms of side effects include injection site reactions. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Weight loss or weight gain has been reported by some people using Ajovy. If you experience this side effect while taking Ajovy, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Ajovy.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your caregiver will monitor your side effects and may adjust your dose of Ajovy as needed.

Otezla side effects and how to avoid them

Otezla is a brand-name medication manufactured by Amgen Inc. It is used to treat moderate to severe plaque psoriasis, active psoriatic arthritis, and oral ulcers associated with Behcet’s disease. While Otezla is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Otezla include upper respiratory tract infections. Less common, but more serious side effects, can include severe allergic reactions.

Learn more about the side effects of Otezla and what you can do to avoid them.

What is Otezla (apremilast)?

Otezla is approved by the FDA to treat adult patients with:

  • Moderate to severe plaque psoriasis that require systemic therapy or light treatment (phototherapy)
  • Moderate to severe active psoriatic arthritis (PsA)
  • Oral ulcers associated with Behcet’s disease

Plaque psoriasis, psoriatic arthritis, and Behçet’s disease can not be cured, but medications can help manage these conditions and reduce symptoms. Otezla can reduce the inflammation caused by your immune system that underlies these conditions, giving you relief from your symptoms and improving your quality of life.

The active ingredient in Otezla is called apremilast, a non-biologic, systemic phosphodiesterase-4 (PDE-4) inhibitor. Apremilast works by blocking an enzyme in your body called phosphodiesterase 4. This enzyme is involved in the process your immune system uses to cause inflammation. By blocking this enzyme, apremilast interrupts this process, reducing inflammation in your body. This can reduce psoriatic skin plaques, limit swelling and pain in your joints, and help clear up and prevent mouth ulcers caused by Behçet’s disease.

Otezla dosage

Otezla is available in 10 mg, 20 mg, and 30 mg tablets. The starting dose of Otezla is typically 10 mg in the morning and titrated up to a dose of 30 mg twice a day.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at your scheduled time.

Read the prescribing information and the medication guide provided with this medicine for the full drug information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Otezla side effects

Side effects usually occur within the first 2 weeks of treatment, and improve as you continue to take it. The most common possible side effects of Otezla in clinical trials compared to placebo-controlled tests include:

  • Injection site reactions
  • Stomach pain, diarrhea
  • Back pain, joint pain
  • Headaches
  • Nausea, vomiting
  • An increase in upper respiratory tract infections
  • Low red blood cells (anemia)

Otezla can cause more serious side effects, including:

  • Severe allergic reactions to the medication – trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, or throat
  • New or worsening mental health conditions, including depression, suicidal thoughts and behaviors, and other mood changes
  • Severe diarrhea, nausea, or vomiting
  • Weight loss

If you experience any of these serious side effects, stop taking Otezla and seek medical attention immediately. You are encouraged to report adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Otezla drug interactions

Otezla can interact with other medications including:

  • Rifampin, an antibiotic usually used to treat tuberculosis
  • Phenytoin, phenobarbital, or carbamazepine, medications used to treat seizures and epilepsy
  • St John’s Wort, an herbal supplement often taken to help with anxiety and depression

Before taking Otezla, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Otezla warnings & precautions

Don’t take Otezla if:

  • Are allergic to the active ingredient apremilast
  • Have known hypersensitivity to any of the other ingredients in Otezla
  • Are under 18 years of age

Talk to your doctor before taking Otezla if you:

  • Are taking any of the medications that could interact with Otezla
  • Have a mental health or mood disorder, like depression
  • Have, or have had, suicidal thoughts or have ever tried to commit suicide
  • Have kidney disease
  • Are prone to severe diarrhea, nausea, or vomiting
  • Are underweight for your height and age
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Otezla, to make sure it is safe for you.

How to avoid Otezla side effects

The best way to avoid side effects is to take Otezla as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Otezla that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Otezla. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Otezla as it can make side effects such as nausea, vomiting, and diarrhea worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Otezla.

7. Know the signs and symptoms of Otezla side effects

Signs and symptoms of side effects include back pain, joint pain, and headaches. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Otezla may cause weight loss. If you experience this side effect while taking Otezla, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Otezla.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Otezla as needed.

What foods to avoid with ulcerative colitis

Ulcerative colitis is one of two types of inflammatory bowel disease (IBD). The other being Crohn’s disease. Ulcerative colitis is a long-term, inflammatory disease of the lower end of your digestive system. This includes the large bowel and rectum. What you eat and drink will not only affect your symptoms of ulcerative colitis but also how severe the symptoms will be.

Here we will look at what ulcerative colitis is, its symptoms, what foods trigger ulcerative colitis and so to avoid, as well as what foods you can eat, and treatments available to improve your quality of life.

What is ulcerative colitis?

Ulcerative colitis is a condition that causes inflammation and sores on the inner lining of your large intestine and rectum. The exact cause of this medical condition is not known but it is thought to be linked to certain environmental factors such as diet and lifestyle as well as genetic factors. A possible cause is your immune system attacking your digestive system.

Ulcerative colitis can cause symptoms such as abdominal pain, cramping, tiredness, and nausea. Your symptoms can be managed with what you eat, and by not eating certain foods you can reduce your flare-ups.

Even though no eating plan will completely prevent flare-ups, a good diet will help you manage your symptoms. You should be aware that as we are all unique and different, what changes in food and diet work for one individual may not work for another. Your diet plan will need to be tailored to your own unique needs.

Symptoms of ulcerative colitis

Symptoms of ulcerative colitis will differ in individuals however, symptoms may include:

  • Abdominal pain
  • Bloating
  • Cramping
  • Stools containing blood or pus
  • Bleeding from your rectum
  • Diarrhea
  • Nausea
  • Fatigue
  • Weight loss

Medication for ulcerative colitis

  • Aminosalicylates – these are taken orally as delayed-release tablets, or rectally as enemas or suppositories. Examples include Pentasa, Dipentum, and Colazal
  • Corticosteroids – these prevent your immune system from working normally but are not specific, and do not target specific parts of the immune system that cause the inflammation. Corticosteroids are not recommended as a long-term treatment for ulcerative colitis. Examples include Deltastone
  • Immunomodulators – these are used when aminosalicylates and corticosteroids have not worked well enough. Examples include Imuran
  • Biologic/biosimilar therapies – these are protein-based therapies that are created from natural sources. Examples include Entyvio, Humira, Remicade, and Simponi

Discuss what the most effective treatment option is for you with your doctor or healthcare provider.

Foods to avoid

The general principle for any diet plan is to eat a healthy balanced diet. If you’re experiencing a flare-up it’s best to avoid foods high in fat or high-fiber foods, such as nuts, seeds, and raw vegetables. Potential triggers that are associated with ulcerative colitis include:

  • Lactose-containing foods such as dairy products – cheese, milk, and yogurt
  • Processed meats and red meat – beef, lamb, and pork. Limit your serving size if you can not completely avoid these foods
  • Alcoholic beverages – beer and grain liquors like vodka and whiskey should be consumed in moderation. Speak to your healthcare advisor for advice
  • Carbonated drinks including soft drinks
  • Artificial sweeteners – mannitol and sorbitol
  • Some fruits – pears, prunes and peaches that are high in sugar
  • Insoluble fiber foods – raw green vegetables such as whole nuts, broccoli, and whole grains. Fruits with skin intact may increase bowel movements, abdominal cramping and gas
  • Sugary foods – cakes, candy, ice cream, and certain fruit juices
  • High-fat foods – butter, fatty meats, coconut, fried, or greasy foods
  • Spicy foods – The Crohn’s and Colitis Foundation states that spicy foods can worsen UC flares. These include hot peppers, chilies, and hot sauces
  • Gluten – wheat, rye, oats, and barley. Studies have shown a gluten-free diet help reduce flare-ups and symptoms
  • Legumes and beans

What foods can I eat?

People who are diagnosed with ulcerative colitis are at an increased risk of having deficiencies in their diet because they may not be able to consume certain foods. Difficulty absorbing nutrients from food may also add to this problem. Individuals with ulcerative colitis are therefore advised to eat foods high in vitamins and minerals, calcium, iron, and vitamin A. Foods you may eat include:

  • Omega-3-rich foods that are high in omega-3 fatty acids such as sea food. This includes mussels, scallops, anchovies, mackerel, and sardines
  • Some probiotic foods – yogurts containing active probiotics have been shown to help reduce ulcerative colitis flare-ups and symptoms
  • Low-fiber fruits – bananas, cantaloupes, and cooked fruits
  • Refined grains – potato, white pasta, gluten-free bread, white rice, and oatmeal
  • Lean protein – fish, chicken, eggs, and firm tofu
  • Cooked vegetables – cucumbers, squash, and asparagus tips
  • Water, as diarrhea can lead to dehydration
  • Dietary supplements to make sure you get enough nutrients. Consult your dietitian before initiating supplements
  • A Low-residue diet or low-fiber diet – white bread, refined breakfast cereals, such as cornflakes, white rice, refined pasta and noodles

Ulcerative colitis diet plans

A handy tip is to keep a food journal to help identify the foods that are your triggers. Essentially those foods that bring about an attack. Your food journal should allow you to make decisions about which foods you should or should not eat. Some helpful information to include in your journal:

  • The foods you have eaten
  • The date and time
  • What reactions you have had
  • When you had worsening symptoms or flare-ups
  • Any stressful events or periods of anxiety that bring about flare-ups

Food journals are useful when you’re looking to add certain foods to your diet. Add one food at a time and record your symptoms. This way you can see if a certain food is suitable or not.

Your diet plan should include:

  • Foods to eat and avoid
  • How to change foods rather than avoiding them completely. Cooking or peeling a fruit or vegetable might make all the difference and may mean you do not miss out on essential nutrients needed for a healthy balanced diet
  • Supplements you can take to replace any nutrients you cannot get in your food. Discuss with a registered nutritionist or dietitian about which supplements are suitable for you
  • Meal plans – these will help you to stick to foods that do not make your symptoms worse
  • Any advice given to you by your doctor or dietitian

Your ulcerative colitis symptoms may change over time, so it is important to keep a track of these changes. Record and review changes in your diet and speak to your healthcare provider if flare-ups become worse or occur more often than usual.

Premade diet plans such as the low FODMAP diet are available and can be beneficial. However, as mentioned before, we are all different, and what works for me may not work for you. Speak to your nutritionist or a registered dietitian to develop a healthy eating plan and to discuss other lifestyle changes you can make to manage your condition better.

What foods to avoid with gout

Gout is a form of arthritis that develops if you have too much uric acid (hyperuricemia) in your body. When high levels of uric acid increase in your body it can lead to joint pain. What you eat and drink will not only affect your symptoms of gout but also how severe the symptoms will be. High-purine foods will cause more gout symptoms and problems than foods low in purine.

Here we will discuss what gout is, its symptoms, what you can do to reduce your risk of gout flare-ups and what foods you should avoid.

What is gout?

Gout is a type of arthritis that develops when you have too much uric acid in your body. Uric acid is made from purine a substance found in many different types of foods. Consuming foods containing high levels of uric acid cause uric acid levels to increase in your body and urate crystals to form in your joints. This build-up of crystals in your joints causes the symptoms of gout, namely pain and inflammation.

Even though no eating plan will prevent flare-ups completely, a good diet will help you manage your gout by reducing the amount of purines you eat. You should be aware that as we are all unique and different, what changes in food and diet work for one individual may not work for another. Your diet plan will need to be tailored to your own unique needs.

Symptoms of gout

The pain and inflammation experienced in gout are caused by urate crystals entering joints, fluids, and tissues in your body. The pain and inflammation may affect only one joint, most often the big toe, or more often multiple joints at the same time.

The symptoms of gout may include severe joint pain, joint stiffness or swelling, redness at the affected site, feeling tired, and mild fever.

Be aware, gout may not always cause the symptoms of pain and inflammation immediately but instead may develop over time and get worse if not treated. Your doctor will be able to better help you recognize and understand your symptoms, diagnose the cause of your symptoms, and discuss the treatment options available, such as changes in your diet.

Does weight loss help to prevent gout

It is a well-known fact that being overweight can cause excess stress on your joints, especially your lower limbs. This can cause pain and inflammation, and more damage to joints in your knees and feet. It has been calculated that being just 10 pounds overweight will increase the force on your knees by 30 to 40 pounds. The extra load has also been shown to stimulate the release of more chemicals that can cause more joint damage.

If you have joint pain induced by excess weight losing pounds and taking the stress off your joints will ease your symptoms. Your body can not reverse arthritis but, losing excess weight can help your joints feel better and prevent further damage. A review of studies has shown that losing eight pounds or more will lead to reductions in your uric acid levels and reduce your risk factors for gout attacks if you are overweight or obese.

Treatments for gout

Treatment options for gout include pain relief medications such as nonsteroidal anti-inflammatory drugs (Ibupak), colchicine (Colcrys), and steroids (Medrol), as well as drugs such as allopurinol to reduce uric acid levels. You may also use topical treatments for local relief. Treatments such as ibuprofen gel may be helpful.

Vitamins such as folate, vitamin B6, vitamin B12, or vitamin C supplements may be recommended to you during a flare-up. You may also take methotrexate during a flare-up. Talk to your doctor about taking folic acid if a healthcare professional prescribes methotrexate.

Exercise is also a useful treatment. In addition to its obvious health benefits, exercise will help you reduce your weight and take some of the excess stress off your weight-bearing joints (feet, ankles, and knees). Consider exercises such as swimming or riding a bike, as these types of exercises are especially good options for patients with gout as they don’t put as much pressure on your weight-bearing joints.

What foods should I avoid with gout?

The general principle for any diet plan is to eat a healthy balanced diet. Foods that trigger gout attacks and cause gout flare-ups are high in purines. If you have gout you should avoid foods high in purine, these include:

  • Sweet sugary foods such as sugary drinks like soda, cereal, ice cream, candy, chocolate, some fruit juices, and high fructose corn syrup
  • Processed foods – chips, white bread, cakes, cookies
  • High-fat dairy products – full-fat milk, butter, cheese
  • Red meat – beef, lamb, and pork. Limit your serving size if you can not completely avoid these foods
  • Organ meat – liver, kidney, thymus, or pancreas (these are often called sweetbreads)
  • Game meats – venison and wild-caught birds
  • Yeasts
  • Alcoholic beverages – beer and grain liquors like vodka and whiskey should be consumed in moderation. Speak to your healthcare advisor for advice
  • Seafood – shellfish like shrimp, lobster, mussels, scallops, anchovies, mackerel, and sardines. The health benefits of eating fish need to be considered. Moderate portions of fish can be part of a healthy gout diet and avoiding all types of seafood may have detrimental effects on your general health

What foods can I eat with gout?

As stated previously a gout diet typically follows a healthy diet. Low-purine diet options include:

  • Lean meat and poultry such as chicken and turkey
  • Low-fat dairy – yogurt, skimmed milk, low-fat cheeses
  • Lentils
  • Complex carbohydrates – fruits, vegetables, and whole grains (whole grains can also help to reduce the risk of other health conditions such as heart disease, stroke, type 2 diabetes, and obesity). Studies have shown that vegetables such as asparagus and spinach do not increase the risk of gout
  • Wholegrain foods such as wheat germ, bran, and oatmeal
  • Nuts, peanut butter, and grains
  • Fatty and oily foods
  • Potatoes, rice, bread, and pasta
  • Eggs

What drinks are safe during a gout flare-up

Make sure you drink plenty of fluids, about 8 to 16 cups a day, with at least half of what you drink being water. Drinks that contain Vitamin C can also help reduce uric acid levels, but be careful. Studies have shown that the high sugar content in certain drinks such as orange juice may actually increase your uric acid levels.

Moderate consumption of coffee has also been shown to cut your uric acid levels too. Talk to your healthcare advisor about your consumption of coffee, especially if you have other medical conditions.

Beer and distilled liquors such as whiskey and vodka are linked with an increased risk of gout and recurring gout attacks. You should avoid alcohol during gout attacks, and limit alcohol consumption between attacks. Speak to your doctor for advice about what is considered healthy alcohol consumption.

Will going gluten-free help with my gout?

Research suggests that eating gluten-free could improve your gout symptoms. Gluten-free food includes buckwheat, rice, quinoa, polenta, fresh meat, fresh fish, eggs, milk, cream, crème fraîche, and natural yogurt. You’ll notice that some of the foods you should avoid are listed here. This can be quite confusing, but as we said before we are all different and what works for me may not work for you. It’s always best to consult with your doctor or dietitian if you are considering a gluten-free diet.

A handy tip is to keep a food journal to help identify the foods that are your triggers. Essentially those foods that bring about a gout attack. Also, keeping track of any stressful events or periods of anxiety that bring about flare-ups may be useful. Discuss your condition with your doctor or dietitian to develop a healthy eating plan and to discuss other lifestyle changes you can make to manage your condition better.

What foods to avoid with Crohn’s disease

Crohn’s disease can create problems for people experiencing a flare-up when it comes to eating, as certain foods may make their symptoms worse. Symptoms during a flare-up include diarrhea, nausea, and stomach cramping.

Here we will discuss what Crohn’s disease is, the treatments available, how to manage a flare-up, and suggestions for a daily diet.

What is Crohn’s disease?

Crohn’s disease is classed as a type of inflammatory bowel disease (IBD). It causes inflammation in your digestive tract (mainly the small intestine), leading to abdominal pain, severe diarrhea, weight loss, tiredness, and malnutrition. There is no known cure for Crohn’s disease, but treatments can reduce your symptoms and bring about long-term remission and healing of the inflammation.

Symptoms

Crohn’s disease can affect any part of your digestive system. Symptoms can range from mild to severe, and develop gradually, but sometimes will come on without any warning. Symptoms include:

  • Gastrointestinal symptoms – chronic diarrhea, abdominal pain, bloating, and cramping
  • Fever
  • Tiredness
  • Blood in your stool
  • Mouth sores
  • Reduced appetite and weight loss
  • Pain or drainage near or around the anus

If you suffer from severe Crohn’s disease you may also have symptoms outside of the intestinal tract, including:

  • Inflammation of skin, eyes, joints, liver or bile ducts
  • Kidney stones
  • Anemia
  • Delayed growth or sexual development, in children

See a registered dietitian for medical advice if you have persistent symptoms.

Treatment for Crohn’s disease

There are a range of drug classes available for the treatment of Crohn’s disease. These include corticosteroids, immunomodulatory, and biologics drugs.

Treatments such as Humira, Remicade, and Stelara all help to reduce inflammation in the body and are used for the treatment of a variety of conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis, as well as Crohn’s disease, juvenile idiopathic arthritis, ulcerative colitis, and uveitis.

Your doctor will decide which medication is the most appropriate for you based on your age, medical condition, and your symptoms.

What foods should I avoid with Crohn’s disease?

Doctors and dietitians will recommend you avoid high-fiber foods and foods known to stimulate the gut, such as spicy foods, during a Crohn’s disease flare-up. Foods to avoid include:

  • Beverages – alcoholic, caffeinated, carbonated, or highly sweetened
  • Bread and starches – brown rice, cereals containing nuts, dried fruit, or seeds, quinoa, whole grain bread, crackers, bran cereal, pasta
  • Dairy products – Crohn’s disease can also cause lactose intolerance, the inability to digest sugar in milk and other dairy products. Avoid cheeses containing nuts or seeds, and yogurts containing fruit skins
  • Fats – coconut, nuts, salad dressings with poppy seeds
  • High-fat foods – butter, margarine, or any deep-fried food items
  • Fruit – raw fruit and fruit juices with pulp, dried fruit, and prune juice. Ripe bananas, melons, and apples with the skin removed are safe to consume during a flare-up
  • High fat and high fiber protein sources – beans, fried eggs or meat, salami, chunky nut butter with seeds, and peas
  • Sweets and desserts – foods containing bran, cookies, candy, cakes, pastries, fruit juice with added sugar, ice cream, dried fruit, jams, and raisins
  • Vegetables – beets, broccoli, cabbage, greens, onions, parsnips, peppers, and spinach

Eating when in remission

Remission is when your symptoms have subsided, or even disappeared. Foods that can help you stay healthy and hydrated include:

  • Fiber-rich foods – oat bran, beans, barley, nuts, and whole grains
  • Lean Protein – lean meats, fish, eggs, nuts, and tofu
  • Fruits and vegetables
  • Calcium-rich foods – collard greens, yogurt, kefir, and milk
  • Food with probiotics – yogurt, kimchi, miso, sauerkraut, and tempeh

Food and drinks to consume during a flare-up

Crohn’s disease or ulcerative colitis can cause serious complications, including nutrient deficiencies, weight loss, and malnutrition.

The Crohn’s and Colitis Foundation recommends a low-residue diet plan, similar to a low-fiber diet, that also limits foods that reduce the amount of solid waste in your stools. A low-residue diet helps your bowel rest and recover because the intestinal tract does not have to work as hard to digest foods. You should otherwise aim to eat a balanced diet with adequate amounts of fiber.

  • Beverages – decaffeinated drinks, low sugar rehydration drinks, water
  • Bread and starches – low-fiber bread and cereal options such as bread made with white, refined, or all-purpose flour, refined cereals such as grits or puffed rice, and white rice
  • Dairy products – if dairy products do not worsen your symptoms you may eat 2 servings or less of cheese, milk, or yogurt with live active cultures
  • Fruit – canned fruit, except for cherries or berries, peeled apples or applesauce, pulp-free fruit juices, ripe bananas or melons
  • Proteins – eggs (where the yolk is solid), fish, poultry, and soy products, protein shakes, or oral protein supplements
  • Vegetables – asparagus, canned vegetables without seeds, well-cooked vegetables, eggplant, potatoes without the skin, and pumpkin

The Ulcerative Colitis & Crohn’s Disease Cookbook has more than 170 recipes for people living with Crohn’s disease or IBD. The Low Residue Diet Cookbook also has many low-residue diet recipes.

Your doctor may recommend taking vitamins, such as folate, vitamin B6, and vitamin B12 during a flare-up. You may also take the medication methotrexate during a flare-up. Talk with your doctor about folic acid supplementation if a healthcare professional prescribes methotrexate.

Will going gluten-free help with my Crohn’s disease?

Research does not suggest that eating gluten-free could improve your Crohn’s disease symptoms. Consult your doctor if you are considering a gluten-free diet.

Diet tips and preventing flare-ups

There is no single food group linked to every case of Crohn’s disease. Different foods may irritate the gut and cause inflammation in different people. Diet tips include:

  • Eat several small meals daily instead of large meals
  • Drinking plenty of water throughout the day
  • Add fiber sources slowly

A food journal may be helpful to identify your trigger foods. Triggers may include lactose or certain carbohydrates. Also, note any stressful events or periods of anxiety, as these too can bring about flare-ups. Discuss specific recommendations with your doctor or nutritionist regarding your diet and develop a healthy eating plan.

Tremfya side effects and how to avoid them

Tremfya is a brand-name medication manufactured by Janssen Biotech, Inc. It is classed as a biologic monoclonal antibody used to treat moderate to severe plaque psoriasis and active psoriatic arthritis. While Tremfya is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Tremfya include injection site reactions and infections. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Tremfya and what you can do to avoid them.

What is Tremfya (guselkumab)?

Tremfya (guselkumab) injection is a prescription medication given to adults to treat:

  • Psoriatic arthritis
  • Moderate to severe plaque psoriasis – Tremfya may be an option if you can receive systemic therapy or phototherapy

Plaque psoriasis and psoriatic arthritis are inflammatory autoimmune diseases triggered by the same underlying immune system disorder. They’re caused by your immune system mistakenly attacking healthy parts of your body, causing inflammation. While inflammation is usually beneficial, as it helps your body heal and protect itself from infection, inflammation in healthy tissue can cause damage.

The active ingredient in Tremfya is called guselkumab. It’s an interleukin-23 blocker that has been designed to block a substance in your body called a cytokine. Cytokines are a type of protein released by your immune system that attaches to the outside of cells, triggering them to begin the inflammatory process. Tremfya reduces how much inflammation your immune system can cause. This can help to ease your symptoms and to make flare-ups of symptoms less likely. Tremfya is sometimes used alone, and sometimes it’s used alongside other treatments, as directed by your doctor.

Tremfya dosage

Tremfya is available as an injection, as 100 mg/mL in a single-dose prefilled syringe, or as a single-dose One-Press injector.

Use Tremfya by injecting it under your skin (subcutaneous injection). Your doctor or another healthcare professional will show you how to do this. You usually take Tremfya once, wait four weeks, take it a second time, then once every eight weeks after that. Tremfya may be used alone or with methotrexate. If you miss a dose, use the medicine as soon as you remember, but skip the missed dose if it is almost time for your next dose.

Store Tremfya in the refrigerator. Protect from light and do not freeze. Allow Tremfya to reach room temperature for 30 minutes before injecting your dose. Do not shake the prefilled syringe, and only prepare your dose when you are ready to give an injection.

You are advised to read the medication guide and instructions for use provided with this medicine for the full drug information and to always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Tremfya side effects

The most common possible side effects of Tremfya include:

  • Stuffy nose, sneezing, sore throat, cough, feeling short of breath
  • Injection site reactions
  • Headaches
  • Diarrhea, stomach pain
  • Gastroenteritis
  • Joint pain (arthralgia)
  • An increased risk of upper respiratory infections, like colds and sinus infections
  • An increased risk of bronchitis
  • An increased risk of fungal infections
  • An increased risk of herpes simplex infections

Tremfya can also cause more serious side effects. These are rarer but they can include:

  • Serious allergic reactions to the medication that can cause skin rashes, hives, dizziness, chest tightness, and swelling in your face, tongue, and throat that can cause trouble breathing and shortness of breath
  • An increased risk of developing a serious infection, like tuberculosis and pneumonia, as Tremfya can reduce your immune system’s ability to fight infections. Signs of infection include fever, muscle aches, night sweats, weight loss, tiredness, shortness of breath, pain or burning when you urinate, skin redness, tingling, blisters, or sores

If you experience any of these serious side effects, stop taking Tremfya and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Tremfya drug interactions

Tremfya can interact with other medications including:

  • Any other medications you’re taking for plaque psoriasis or psoriatic arthritis, including topical medications (products you apply directly to your skin)
  • Any medications you’re taking to treat a bacterial, viral, or fungal infection – any antibiotics, antivirals, or antifungal agents

Before taking Tremfya, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Tremfya warnings & precautions

Tremfya isn’t suitable for everyone. Don’t take Tremfya if you:

  • Are allergic to the active ingredient guselkumab
  • Are allergic to any of the other ingredients in Tremfya
  • Are under 18 years of age

Talk to your doctor before taking Tremfya if you:

  • Are taking any of the medications that could interact with Tremfya
  • Have tuberculosis or have recently been in contact with someone with tuberculosis
  • Are currently being treated for an infection or have an untreated infection
  • Have an infection that keeps going away and then coming back
  • Have recently had a live vaccine or are due to have a vaccine
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is unknown if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Tremfya, to make sure it is safe for you.

How to avoid Tremfya side effects

The best way to avoid side effects is to take Tremfya as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Tremfya that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Tremfya. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Make sure you drink plenty of water or fluids every day to help prevent dehydration, especially if you have the side effect of gastroenteritis.

4. Avoid alcohol

Tremfya does not interact with alcohol, but alcohol may increase inflammation in your body and make your plaque psoriasis or psoriatic arthritis worse.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Tremfya.

7. Know the signs and symptoms of Tremfya side effects

Signs and symptoms of side effects of Tremfya include respiratory infections. If you experience any of these symptoms talk to your caregiver for medical advice.

8. Monitor your weight

Weight loss may be a sign of an infection, such as tuberculosis, or other conditions that require treatment.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Tremfya.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your caregiver will monitor your side effects and may adjust your dose of Tremfya as needed.

Brilinta side effects and how to avoid them

Brilinta is a brand-name medication manufactured by AstraZeneca. It is classed as an antiplatelet and is used to reduce the risk of heart attacks and strokes. While Brilinta is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Brilinta include an increased risk of bleeding. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Brilinta and what you can do to avoid them.

What is Brilinta (ticagrelor)?

Brilinta is an FDA (U.S. Food and Drug Administration) approved medication used to reduce the risk of heart attacks, strokes, and death from heart disease caused by blood clots blocking blood vessels. It’s prescribed to adults who:

  • Have previously had a heart attack (myocardial infarction)
  • Have coronary artery disease (CAD) and are at a high risk of having a heart attack or a stroke
  • Have acute coronary syndrome (ACS), which occurs when blood flow to the heart is suddenly blocked
  • Have ACS and who have been treated with a stent

If you have CAD, ACS, or have a stent due to ACS, you may be at a higher risk of blood clots. Brilinta helps to stop your blood clotting, reducing your risk of a heart attack or stroke. The active ingredient in Brilinta, ticagrelor, inhibits platelet activation by binding to receptors on the surface of your platelets. This stops them from being able to stick together preventing the process that causes clotting.

Brilinta dosage

Brilinta is available in tablet form, in the following doses: 60 mg and 90 mg tablets. Your loading dose and maintenance dose will be based on the condition you are being treated for.

When Brilinta is prescribed for lowering the risk of stroke in people having an ischemic stroke or a transient ischemic attack, a loading dose of aspirin is also given. The combination of aspirin and a P2Y12 inhibitor such as Brilinta is called dual antiplatelet therapy (DAPT). If you miss a dose of Brilinta, skip the missed dose and take your next dose at the usual time. Do not double your doses.

You will take Brilinta for at least 12 months after stent placement. After the first 12 months, you will take Brilinta for a further 12 months at a reduced dose. Your doctor will decide your dose at your follow-up appointment to determine any changes.

You are advised to read the prescribing information and medication guide provided with this medicine and to speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Brilinta side effects

The most common possible side effects of Brilinta include:

  • An increase in minor bleeding risk, including nosebleeds and bruising
  • Shortness of breath (dyspnea)
  • Dizziness
  • Feeling sick (nausea)

Brilinta can cause more serious side effects, including:

  • Increased risk of bleeding such as serious internal and external bleeding that could potentially be fatal. Symptoms of serious bleeding may include bloody or black stools, red or brown urine, coughing up blood or vomit that looks like coffee grounds
  • Heart problems such as changes in heart rhythm, or abnormally slow heart rate
  • Life-threatening allergic reactions to the medication that could cause swelling in your face, mouth, or throat, chest pain (angina), heart palpitations, or trouble breathing

If you experience any of these serious side effects, stop taking Brilinta and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Brilinta drug interactions

Brilinta can interact with other medications including:

  • Any medications taken to treat heart conditions or high blood pressure
  • Digoxin
  • Treatments for high cholesterol – lovastatin, simvastatin
  • Any blood thinner (anticoagulant) medications taken to reduce your risk of blood clots – clopidogrel, heparin, warfarin
  • Any pain killers – codeine, ibuprofen
  • Antidepressants – nefazodone
  • Any antibiotics – erythromycin, rifampin, clarithromycin
  • Any medications taken to treat HIV/AIDS – ritonavir, atazanavir
  • Antifungal medicines – itraconazole, ketoconazole
  • Any anti-seizure medications – carbamazepine, phenobarbital, phenytoin

Before taking Brilinta, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Brilinta warnings & precautions

You should not use Brilinta if you:

  • Are allergic to the active ingredient ticagrelor
  • Are allergic to any of the other ingredients in Brilinta
  • Have ever had bleeding in your brain
  • Are currently bleeding

Talk to your doctor before using Brilinta if you:

  • Have ever had a stroke
  • Have ever had any problems with bleeding
  • Have ever had stomach ulcers or colon polyps
  • Have any liver problems
  • Have asthma or chronic obstructive pulmonary disease (COPD)
  • Have recently had surgery or a serious injury
  • Are planning to have surgery or a dental procedure
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Brilinta, to make sure it is safe for you.

Other warnings you should know about

Ticagrelor may increase the risk of serious bleeding during surgery, or other medical procedures such as coronary artery bypass graft (CABG), or dental work. Stop using Brilinta at least 5 days before surgery, medical procedure, or dental work.

How to avoid Brilinta side effects

The best way to avoid side effects is to take Brilinta as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Brilinta that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Brilinta. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Brilinta as you will also be taking aspirin which can increase your risk of stomach bleeds and ulcers.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Brilinta.

7. Know the signs and symptoms of Brilinta side effects

Signs and symptoms of side effects include an increased risk of bleeding. If you experience any of the symptoms of this side effect speak to your doctor for medical advice.

8. Monitor your weight

Brilinta may cause weight gain. If you experience this side effect while taking Brilinta, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Brilinta.

10. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Brilinta as needed.

Ubrelvy side effects and how to avoid them

Ubrelvy is a brand-name medication manufactured by Allergan. It is classed as a calcitonin gene-related peptide (CGRP) receptor antagonist and is used for the fast-acting relief of migraine symptoms in adults. While Ubrelvy is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Ubrelvy include drowsiness. Less common, but more serious side effects, can include allergic reactions.

Learn more about the side effects of Ubrelvy and what you can do to avoid them.

What is Ubrelvy (ubrogepant)?

Ubrelvy is an FDA (U.S. Food and Drug Administration) approved medication. It contains ubrogepant as the active ingredient. Ubrelvy is not a triptan, it belongs to a class of drugs called CGRP receptor antagonists. Ubrelvy works by preventing CGRP from attaching to CGRP receptors on nerve endings. It is indicated for the acute treatment of migraine headaches with or without aura in adults. It is not recommended for the preventive treatment of migraine attacks.

Ubrelvy dosage

Ubrelvy is available in tablet form, in the following doses: 50 mg and 100 mg. The recommended dose is 50 mg or 100 mg orally, as needed. If needed, a second dose may be administered at least 2 hours after the initial dose. The maximum dose in a 24-hour period is 200 mg. For severe hepatic or renal impairment, the recommended dose is reduced to 50 mg if needed. A second 50 mg dose may be taken at least 2 hours after the initial dose.

Please read the full patient information and drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Ubrelvy side effects

The most common side effects of Ubrelvy in clinical trials compared to placebo include:

  • Nausea
  • Tiredness
  • Dry mouth
  • Drowsiness, sleepiness

In rare instances, Ubrelvy can cause more serious side effects. These can include:

  • Allergic reactions – hives, difficulty breathing, swelling of your face, lips, tongue, or throat

If you experience any of these serious side effects, stop taking Ubrelvy and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ubrelvy drug interactions

Ubrelvy can interact with other medications including:

  • Strong CYP3A4 inhibitors – ketoconazole, clarithromycin, itraconazole
  • Moderate CYP3A4 inhibitors – cyclosporine, ciprofloxacin, fluconazole, fluvoxamine, grapefruit juice
  • Strong CYP3A4 inducers – phenytoin, barbiturates, rifampin, St. John’s Wort
  • Heart or blood pressure medicine – carvedilol, quinidine, verapamil

This list is not exhaustive and other prescription drugs may interact with Ubrelvy. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Ubrelvy warnings & precautions

You should not use Ubrelvy if you:

  • Are allergic to the active ingredient ubrogepant
  • Have had an allergic reaction to any of the other ingredients in Ubrelvy
  • Have end-stage renal disease

Talk to your doctor about your medical conditions before using Ubrelvy if you:

  • Are taking any of the medications that could interact with Ubrelvy
  • Have liver problems
  • Have kidney disease
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Ubrelvy, to make sure it is safe for you.

How to avoid Ubrelvy side effects

The best way to avoid side effects is to take Ubrelvy as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Ubrelvy that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Drink plenty of fluids

Ubrelvy is not associated with causing dehydration. Dehydration however can trigger migraine attacks. Make sure you drink plenty of water to prevent this.

3. Avoid alcohol

Alcohol does not interact with Ubrelvy, but alcohol and Ubrelvy can both cause nausea and sleepiness, and taking both could increase your risk of these side effects.

4. Know the signs and symptoms of Ubrelvy side effects

Signs and symptoms of side effects include nausea, tiredness, and drowsiness. If you experience any of these symptoms speak to your doctor for medical advice.

5. Monitor your weight

Weight gain or weight loss have not been reported as side effects of Ubrelvy.

6. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Ubrelvy.

7. Get regular medical check ups

It is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Ubrelvy as needed.

Victoza side effects and how to avoid them

Victoza is a brand-name medication manufactured by Novo Nordisk. It is classed as a glucagon-like peptide-1 agonist (GLP-1) and is used to improve blood sugar levels in people with type 2 diabetes mellitus and reduce the risk of major cardiovascular events, such as heart attack and stroke. While Victoza is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Victoza include indigestion and constipation. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Victoza and what you can do to avoid them.

What is Victoza (liraglutide)?

Victoza is manufactured by Novo Nordisk. It has FDA (Food and Drug Administration) approval to help control high blood sugar levels in people with type 2 diabetes. The active drug in Victoza is liraglutide, which is also the active ingredient in Saxenda.

RELATED: Saxenda vs Victoza

Victoza is usually prescribed when people can not control their blood sugar through diet and exercise alone, or if their diabetes medication isn’t effective. Victoza can be used alone or in combination with other diabetes medicines. Using Victoza may aid weight loss, and help to reduce body weight. This may be especially useful in those patients also suffering from obesity.

When you eat and digest food, sugar is released into your blood so it can be transported around your body. Your body absorbs the sugar out of your blood, returning your blood sugar to normal levels. In people with diabetes, their bodies struggle to control their blood sugar levels. Often their blood sugar is too high, and over time this can cause a range of problems, including nerve damage and heart disease. When injected, Victoza helps people with type 2 diabetes control their blood sugar levels in three ways:

  • It helps your pancreas produce more insulin
  • It reduces how quickly food moves through your stomach, slowing down the release of sugar into your blood
  • It helps to stop your liver from releasing too much sugar into your blood

Always check with your doctor or pharmacist before taking any medication, including Victoza, to make sure it is safe for you.

Victoza dosage

Victoza is available as a subcutaneous injection, in the following doses: 6 mg/mL. Inject Victoza once daily at any time of day, in the abdomen, thigh, or upper arm. Administer separate injections when using insulin.

Initiate adult dosage at 0.6 mg daily for one week increasing to 1.2 mg daily. Increase the dose to 1.8 mg daily after one week of treatment with the 1.2 mg daily dose if further glycemic control is needed.

Initiate pediatric dosage at 0.6 mg daily for at least one week. Increase the dose to 1.2 mg daily if further glycemic control is needed. If additional glycemic control is still required, increase the dose to 1.8 mg daily.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Victoza side effects

The most common possible side effects of Victoza in clinical trials include:

  • Injection site reactions
  • Nausea
  • Diarrhea
  • Decreased appetite
  • Indigestion, and constipation
  • Low blood glucose (hypoglycemia) – symptoms include confusion, drowsiness, blurred vision, sweating, slurred speech, fast heartbeat, irritability, and mood changes
  • Headaches
  • Anxiety
  • Tremors

Victoza can cause more serious side effects, including:

  • Symptoms of pancreatitis (inflammation of the pancreas)
  • Difficult, burning, or painful urination
  • Worsening of kidney failure and gallbladder problems
  • Increased risk of thyroid tumors and medullary thyroid cancer (medullary thyroid carcinoma (MTC))
  • Serious allergic reactions that can be life-threatening symptoms include swelling of your face, lips, tongue, or throat, trouble breathing, shortness of breath, severe rash or itching, feeling fainting or dizzy, increased heart rate

If you experience any of these serious side effects, stop taking Victoza and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Victoza drug interactions

Victoza can interact with other medications including:

  • Antibiotics for bacterial infections such as gatifloxacin
  • Bexarotene used to treat skin cancer
  • Any other diabetes medications, like insulin or sulfonylureas
  • Diuretics, taken to make you lose water and salt, usually to treat high blood pressure – bumetanide, furosemide
  • Corticosteroids such as cortisone and prednisolone
  • Beta 2-stimulants, taken to treat asthma – salmeterol
  • Estrogen-containing drugs including birth control and hormone replacements
  • Steroids used topically (on the skin) such as betamethasone, clobetasol, hydrocortisone, and mometasone

Before taking Victoza, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Victoza warnings & precautions

You should not use Victoza if you:

  • Are allergic to the active ingredient liraglutide
  • Are allergic to any of the other ingredients found in Victoza
  • Have multiple endocrine neoplasia syndrome type 2 (MEN2)
  • Have type 1 diabetes or diabetic ketoacidosis

Talk to your doctor before using Victoza if you:

  • Have severe heart disease
  • Have severe liver disease
  • Have kidney problems such as kidney disease, or kidney failure or are on dialysis
  • Have ever had cancer or have a family history of cancer
  • Have a severe stomach or gut problem
  • Have gallbladder disease
  • Have gastroparesis
  • Have inflammatory bowel disease
  • Symptoms of acute pancreatitis (like a persistent, severe stomach ache)
  • Have thyroid disease
  • Are pregnant or are planning to become pregnant – Animal studies have shown that Victoza can harm a fetus
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Victoza, to make sure it is safe for you.

How to avoid Victoza side effects

The best way to avoid side effects is to take Victoza as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Victoza that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Victoza. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Victoza as it can increase your risk of side effects such as hypoglycemia.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Victoza.

7. Know the signs and symptoms of Victoza side effects

Signs and symptoms of side effects include confusion, drowsiness, and slurred speech. If you experience any of these symptoms speak to your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Victoza.

9. Get regular medical check ups

If you have diabetes it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Victoza as needed.

Rinvoq side effects and how to avoid them

Rinvoq is an FDA (Food and Drug Administration) approved medication manufactured by Abbvie Inc. “It is used to treat adults with moderate to severe…” Make sure to also add the missing period “ankylosing spondylitis. While Rinvoq is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Rinvoq include upper respiratory tract infections. Less common, but more serious side effects, can include allergic reactions.

Learn more about the side effects of Rinvoq and what you can do to avoid them.

What is Rinvoq (upadacitinib)?

The active ingredient in Rinvoq is upadacitinib, a biologic drug, classed as a Janus kinase (JAK) inhibitor. Upadacitinib prevents the phosphorylation and activation of STATs (signal transducers and activators of transcription).

It is used in patients above 18 years of age requiring treatment for moderate to severely active rheumatoid arthritis, active psoriatic arthritis, active ankylosing spondylitis, and ulcerative colitis for whom methotrexate did not work or could not be tolerated. Rinvoq is currently under review in the U.S. by the Food and Drug Administration (FDA) for use in severe atopic dermatitis (eczema).

Rinvoq dosage

Rinvoq is available in an oral extended-release tablet form, in the following doses: 15mg. Rinvoq may be used alone or in combination with methotrexate or other nonbiologic DMARDs (disease-modifying antirheumatic drugs).

Swallow Rinvoq extended-release tablets whole with a full glass of water, at the same time of day, with or without food. Do not crush, chew, or break the tablet.

If you miss a dose of Rinvoq, take it as soon as you remember. If it is near the time of your next dose, skip the missed dose and take it at the normal scheduled time.

You are advised to read the full prescribing information and medication guide provided with this medicine. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Rinvoq side effects

The most common possible side effects of Rinvoq include:

  • Upper respiratory tract infections
  • Nausea
  • Cough, sore throat
  • Fever, tiredness
  • Increased cholesterol levels
  • Low red blood cell count (anemia)
  • Low white blood cell count

Rinvoq can cause more serious side effects, including:

  • Serious Infections
  • Malignancy
  • Thrombosis
  • Gastrointestinal perforations
  • High cholesterol
  • Increased liver enzymes
  • increased risk of lymphoma (immune system cancer) and other cancers, including skin cancer
  • Allergic reactions – hives, trouble breathing, shortness of breath, chest pain, feeling faint, swelling of your lips, tongue, or throat

If you experience any of these serious side effects, stop taking Rinvoq and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Rinvoq drug interactions

Rinvoq can interact with other medications including:

  • Antibiotics – clarithromycin
  • Statins – atorvastatin
  • Treatments for high blood pressure – lisinopril
  • NSAIDs – meloxicam
  • Methotrexate
  • Anticonvulsants – phenytoin
  • Corticosteroids – prednisone
  • Immunosuppresants – azathioprine, cyclosporine

Before taking Rinvoq, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Rinvoq warnings & precautions

Don’t take Rinvoq if you:

  • Have had an allergic reaction to the active ingredient Rinvoq
  • Are allergic to any of the other ingredients in Rinvoq

Talk to your doctor before taking Rinvoq if you:

  • Are taking any of the medications that could interact with Rinvoq
  • Are being treated for an active infection, have an infection that won’t go away or keeps coming back, or have symptoms of an infection such sweating, chills, shortness of breath, feeling tired, diarrhea, stomach pain, or weight loss
  • Have tuberculosis or have been in close contact with someone with tuberculosis
  • Have a history of blood clots, such as a deep vein thrombosis or a pulmonary embolism
  • Have had any type of cancer
  • Have had hepatitis B or C, or shingles (herpes zoster)
  • Have blood clots in the veins of your legs or lungs
  • Have diverticulitis, or ulcers in your stomach or intestines
  • Have liver problems
  • Have low blood cell counts
  • Have diabetes
  • Have chronic lung disease
  • Have HIV, or a weak immune system
  • Have traveled to parts of the country that increase your risk of getting certain kinds of fungal infections, such as the Ohio, Mississippi River valleys and the Southwest
  • Have recently received or are scheduled to receive a live vaccine
  • Are pregnant or plan to become pregnant. Rinvoq may harm your unborn baby. You should use effective birth control
  • Are breastfeeding or plan to breastfeed. Rinvoq may pass into your breast milk. Do not breastfeed while taking Rinvoq and for at least 6 days after your last dose

You should always check with your doctor or pharmacist before taking any medication, including Rinvoq, to make sure it is safe for you.

Other warnings you should know about

  • Increased risk of major cardiovascular events, such as heart attack, stroke, or death, in people 50 years of age and older who have at least 1 heart disease risk factor, especially if you are a current or past smoker
  • Rinvoq may cause you to get infections more easily, even serious or fatal infections. Viruses such as shingles (herpes zoster), and hepatitis B or C may become active or worse

How to avoid Rinvoq side effects

The best way to avoid side effects is to take Rinvoq as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Rinvoq that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Rinvoq. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Avoid alcohol

There are no known interactions between alcohol and Rinvoq. But Rinvoq may cause liver problems and consuming alcohol while taking Rinvoq may increase your risk for these side effects.

4. Know the signs and symptoms of Rinvoq side effects

Signs and symptoms of Rinvoq side effects include upper repiratory infections. If you experience any of these symptoms speak to your doctor for medical advice.

5. Monitor your weight

Rinvoq may cause weight gain. If you experience this side effect while taking Rinvoq, get medical advice from your doctor.

6. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Rinvoq.

7. Get regular medical check ups

If you have side effects it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Rinvoq as needed.

Emgality side effects and how to avoid them

Emgality is a brand-name medication manufactured by Eli Lilly and Company. It is classed as a calcitonin gene-related peptide receptor (CGRP) antagonist and is used for the treatment of migraine attacks. While Emgality is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Emgality include injection site reactions. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Emgality and what you can do to avoid them.

What is Emgality (galcanezumab-gnlm)?

Emgality is an FDA-approved monoclonal antibody medication classed as a calcitonin gene-related peptide receptor (CGRP) antagonist. By blocking the protein CGRP, it prevents the widening of blood vessels in your brain. Clinical studies show that this helps with migraine prevention and the treatment of the symptoms of a type of headache known as cluster headaches.

Emgality is indicated for the prevention of episodic migraine and chronic migraine headaches, and the treatment of episodic cluster headaches.

Emgality dosage

Emgality is available as a pre-filled syringe and a pre-filled pen with the following strengths:

  • 120mg/ml single-dose pre-filled pen
  • 100mg/ml single-dose pre-filled syringe
  • 120mg/ml single-dose pre-filled syringe

The recommended dose for the preventive treatment of migraines is a 240mg loading dose (2 subcutaneous injections of 120mg) followed by once-monthly doses of 120mg. The recommended dose of Emgality is 300mg (3 subcutaneous injections or 100mg) at the start of the cluster period, then once a month until the cluster period ends.

Use Emgality as prescribed by your doctor. Your doctor should show you or your healthcare provider how to use your Pen or pre-filled syringe before your treatment begins.

Inject Emgality under the skin (subcutaneously) in your abdomen, thigh, buttocks, or the back of your upper arm. If you are using Emgality for the prevention of migraine headaches, you will inject it once a month. Your first dose (loading dose) is given as 2 separate injections right after one another. If you are using Emgality for the treatment of episodic cluster headaches, use it at the start of a cluster period and then monthly until the end of the cluster period.

If you miss a dose, take the missed dose of Emgality as soon as you remember. Inject your next dose after 1 month to get back on your monthly dosing schedule. Store Emgality away from direct sunlight in the refrigerator. You can store Emgality at room temperature for up to 7 days.

You are advised to read the full prescribing information and the instructions for use. Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Emgality side effects

The most common possible side effects of Emgality in clinical trials compared to placebo include:

  • Injection site reactions such as redness, swelling, and pain
  • Constipation
  • Itching
  • Rashes
  • Vertigo (dizziness)

Emgality can cause more serious side effects, including:

  • Serious hypersensitivity reactions, including anaphylaxis (rash, angioedema, hives, and trouble breathing)

If you experience any of these serious allergic reactions, stop taking Emgality and seek medical attention immediately. You are encouraged to report negative adverse reactions to prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Emgality drug interactions

Emgality can also interact with other medications. This can change how Emgality and the other medications work and can make some side effects more likely. Tell your prescribing physician about all drugs you’re taking, including vitamins, and herbal and dietary supplements.

Emgality warnings & precautions

Don’t take Emgality if you:

  • Are allergic to the active ingredient galcanezumab
  • Have had an allergic reaction to any of the other ingredients in Emgality
  • Are under 18 years of age

Talk to your doctor before taking Emgality if you:

  • Are taking any medications or supplements
  • Have any other medical conditions
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Emgality, to make sure it is safe for you.

How to avoid Emgality side effects

The best way to avoid side effects is to take Emgality as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Emgality that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Avoid alcohol

Emgality is not known to interact with alcohol. However, you should be aware that alcohol can trigger migraines for many people.

3. Know the signs and symptoms of Emgality side effects

Signs and symptoms of side effects include injection site reaction, itching, and rashes. If you experience any of these symptoms speak to your doctor for medical advice.

4. Monitor your weight

Emgality is not known to cause weight loss or weight gain.

5. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with Emgality.

6. Get regular medical check ups

If you have side effects it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Emgality as needed.

Anoro Ellipta side effects and how to avoid them

Anoro Ellipta is a brand-name medication manufactured by GlaxoSmithKline. It is used to treat chronic obstructive pulmonary disease (COPD). While the Anoro Ellipta inhaler is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Anoro Ellipta include infections. Less common, but more serious side effects, can include serious allergic reactions.

Learn more about the side effects of Anoro Ellipta and what you can do to avoid them.

What is Anoro Ellipta (umeclidinium/vilanterol)?

Anoro Ellipta is a maintenance treatment prescribed to adults who have chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both. Anoro Ellipta is not for the treatment of asthma. COPD is a lung disease that causes long-term inflammation in your lungs and your airways, making it harder for you to get air in and out of your lungs.

Anoro Ellipta contains two active ingredients, umeclidinium bromide, and vilanterol. They are a bronchodilator combination that work together to help you breathe more easily and to provide relief from your symptoms.

Umeclidinium is an anticholinergic drug that helps to relax and open up your airways. It attaches to the surface of muscle tissue in your airways at sites called muscarinic receptors. This stimulates the muscarinic receptors, causing them to relax the muscle tissue, opening your airways.

Vilanterol is a drug called a long-acting beta-agonist (LABA), and it also helps to relax the muscle tissue in your airways. It attaches to receptors on the surface of muscle tissue, called beta-adrenoreceptors, causing the muscle to relax.

Anoro Ellipta dosage

Anoro Ellipta is an inhalation powder that comes with a preloaded Ellipta inhaler device with blister packs containing measured doses of the medicine. The device loads a blister of Anoro Ellipta each time you use the inhaler.

Use Anoro Ellipta as directed on the label, or as prescribed by your doctor. Use 1 inhalation each day, at the same time each day, and do not use more than once in a 24-hour period. If you miss a dose of Anoro Ellipta use it as soon as you can, but skip the missed dose if it is almost time for your next dose.

Store the inhaler at room temperature away from moisture, heat, and light. Keep the inhaler in the sealed foil tray until ready to use. Discard the inhaler after 6 weeks from opening, or when the dose indicator shows a zero.

You are advised to read the patient information provided with this medicine for the full drug information and to always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Anoro Ellipta side effects

The most common side effects of Anoro Ellipta include:

  • Pharyngitis (sore throat)
  • An increase in respiratory tract infections
  • Urinary tract infection
  • An increase in sinus infections
  • Common cold symptoms
  • Diarrhea
  • Constipation
  • Dry mouth
  • Pain in your arms and legs
  • Neck pain
  • Chest pain
  • Muscle spasms

Anoro Ellipta can cause more serious side effects, including:

  • Serious allergic reactions to the medication that can cause rashes and hives, swelling of your face, mouth, and tongue, and shortness of breath
  • Paradoxical bronchospasm – worsening of your breathing or wheezing
  • Sudden breathing problems immediately after taking the medication
  • Increased blood pressure
  • Palpitations and/or irregular heartbeat and chest pain
  • New or worsening eye problems, including acute narrow-angle glaucoma. Symptoms may include eye pain or discomfort, blurred vision, vomiting or nausea, seeing halos or bright colors around lights, and red eyes
  • Urinary retention – difficulty with urinating, urinating frequently, painful urination,
  • Low potassium levels – leg cramps, constipation, irregular heartbeats, fluttering in your chest

If you experience any of these serious side effects, stop taking Anoro Ellipta and seek medical attention immediately.

Anoro Ellipta drug interactions

Anoro Ellipta can interact with other medications including:

  • Other medications to treat chronic obstructive pulmonary disease
  • Other medicines that contain a LABA (beta2-adrenergic agonist)
  • Beta-blocker medications, taken to manage various heart conditions
  • Diuretic medications, also called water pills, taken to make you urinate more water and salt, often used to lower blood pressure
  • Monoamine oxidase inhibitors (MAOIs)
  • Any anticholinergic medications, like tiotropium, ipratropium, or aclidinium
  • Any HIV medications, including ritonavir
  • Any antifungal medications, including ketoconazole and itraconazole
  • Atropine, taken to treat a range of conditions, including nerve agent and pesticide poisoning, and a slow heart rate

Before taking Anoro Ellipta, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Anoro Ellipta warnings & precautions

Don’t take Anoro Ellipta if you:

  • Are allergic to the active ingredients umeclidinium bromide or vilanterol
  • Have a known hypersensitivity to any of the other ingredients in in Anoro Ellipta, such as lactose
  • Have a severe milk protein allergy
  • Have asthma (Anoro Ellipta is for chronic obstructive pulmonary disease only)
  • Are under 18 years of age

Talk to your doctor before taking Anoro Ellipta if you:

  • Have any heart problems
  • Have high blood pressure
  • Have diabetes
  • Have any liver problems
  • Have any thyroid problems
  • Have seizures
  • Have any eye problems, particularly glaucoma
  • Have any problems that make it difficult to pass urine, like an enlarged prostate or a bladder condition
  • Are allergic to any milk proteins
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Anoro Ellipta, to make sure it is safe for you.

Other warnings you should know about

  • Anoro Ellipta is not used to treat sudden symptoms of COPD. You should always keep a rescue inhaler (an inhaled, short-acting bronchodilator) with you to treat sudden symptoms of COPD
  • You are recommended not to use other anticholinergic drugs such as ipratropium, tiotropium, or LABA drugs such as formoterol, or salmeterol while using this medication

How to avoid Anoro Ellipta side effects

The best way to avoid side effects is to take Anoro Ellipta as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Anoro Ellipta that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Anoro Ellipta. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

4. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Anoro Ellipta.

5. Know the signs and symptoms of Anoro Ellipta side effects

Signs and symptoms of side effects of Anoro Ellipta include upper respiratory tract infections and urinary tract infections. If you experience any of these symptoms speak to your doctor for medical advice.

6. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Anoro Ellipta.

7. Get regular medical check ups

If you have COPD it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Anoro Ellipta as needed.

What foods to avoid while taking metformin

There are no specific foods that you need to avoid while taking metformin. However, you are recommended to watch what you eat while taking this medication to prevent or reduce the potential side effects.

Here we will discuss what metformin is, how it works, its side effects and interactions, and the foods you should or should not eat.

What is metformin?

Metformin is an FDA-approved first-line treatment for diabetes management in people with Type 2 diabetes mellitus.. It is also used for the prevention of prediabetes. Metformin (brand names include Glucophage) is a generic anti-diabetic medication used as part of a treatment plan for Type 2 diabetes. It can be used alone or in combination with other medications.

Metformin may also be used for the treatment of polycystic ovary syndrome (PCOS), a condition that affects ovulation and may increase androgen production. PCOS increases the risk of developing obesity, depression, infertility, and type 2 diabetes. Metformin has been used to help women with PCOS reduce waist size and help with weight loss. Metformin can also be used for the treatment of metabolic syndrome. Metformin is not recommended for the treatment of type 1 diabetes.

What foods have natural metformin?

Metformin is available naturally in the plant Galega officinalis (French lilac or goat’s rue). It is also present in fruits and vegetables as part of our normal diet and may play a part in the management of diabetes naturally.

How does metformin work?

Metformin is classed as a biguanide and used as a first-line treatment for diabetes because of its mode of action in increasing the body’s insulin sensitivity. Also, metformin does not cause weight gain.

It is used in combination with changes to diet and exercise to improve glycemic control in adults and pediatric patients with type 2 diabetes mellitus. It works by reducing the amount of glucose absorbed from your intestines, decreasing how much glucose is made in your liver, and improving your insulin sensitivity.

Metformin dosage

Metformin is available as an immediate-release or extended-release oral tablet, or as an oral suspension. It is taken with meals, unless your doctor tells you otherwise. Do not crush, chew, or break the extended-release tablet. Swallow it whole. Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. You may also be prescribed extra vitamin B12 while you are taking this medicine.

Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of metformin?

The most common side effects of metformin in clinical trials include:

  • Lower blood sugar levels
  • Gastrointestinal side effects such as nausea and diarrhea

More serious side effects of metformin include

  • Unusual muscle pain
  • Problems breathing
  • Dizziness, feeling faint
  • Feeling tired
  • Stomach pain
  • Vomiting
  • Slow or irregular heart rate
  • Lactic acidosis – symptoms include unusual muscle pain, difficulty breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired

What happens if you take metformin on an empty stomach?

Upset stomach is the most common side effect of taking metformin and taking metformin on an empty stomach may make this side effect worse.

Do some foods make the side effects of metformin worse?

Yes, there are some foods that can make the side effects of metformin worse. These include high-fat foods, sugary foods, and alcoholic beverages. Eating these types of foods can also raise your blood sugar levels.

The most common side effects reported by people who take metformin are nausea and diarrhea. Fortunately, you can prevent or reduce these side effects by taking care of what you eat.

People who are taking metformin and experience nausea should consider doing the following:

  • Eating slower
  • Eating smaller meals
  • Eating foods that are bland and light
  • Drinking ice-cold or clear drinks (for example, unsweetened tea or water)
  • Avoiding foods that are sweet, greasy, or fried

What foods make you sick with metformin?

Avoid foods high in sugar. These include cakes, biscuits, juice, fizzy drinks, sweets, chocolates, rich desserts, simple and refined carbs such as white bread, pasta and white rice, and saturated and trans fats. These foods will all increase insulin resistance and raise your blood sugar levels.

What foods should I avoid while taking metformin?

There are no specific foods that you need to avoid while taking metformin however, it is recommended to watch what you eat while taking this medication to prevent or reduce the potential side effects. Avoid foods that are high-fat, sugary, and calorie-dense:

  • Simple and refined carbs which increase your blood glucose levels. Simple carbs include soda, candy, desserts, white bread, pasta, and white rice
  • Foods high in saturated and trans fats
  • Sodium
  • Avoid large amounts of alcohol as it increases your risk of developing low blood sugar and increases the risk of lactic acidosis (alcohol and metformin together can lead to the build-up of lactic acid in the blood). Reducing alcohol consumption will help to manage your blood sugar levels. Also, drinking alcohol on an empty stomach can reduce your blood sugar. This could be an issue for people using insulin or other diabetes medications that increase insulin levels. One drink per day for women and two drinks per day for men is a safe level of alcohol consumption, however not consuming alcohol may be the best choice
  • Grapefruit juice – animal studies found higher amounts of lactic acid production and increased weight gain
  • Healthy snacks (granola bars or fruit snacks are actually high in sugar)

What foods cause diarrhea with metformin?

Some foods can make the symptoms of diarrhea worse while taking metformin. These foods include vegetables, garlic, onion, dairy products, foods that produce gas, oily or junk food.

Foods to avoid when taking metformin for PCOS

Avoid any foods that can cause a sudden peak in blood sugar levels, such as candy, soda, sweet desserts, chips, white bread, or crackers.

High fiber foods to avoid on metformin

Avoid foods such as avocado, berries, beans, chia seeds, chickpeas, and oatmeal.

Can I eat sugar while taking metformin?

Eating foods high in sugar will essentially work against what the metformin is being taken for. You are recommended to avoid or at the very least try to limit foods high in sugar.

What are the best foods to eat while taking metformin?

There are no specific foods that you need to eat while taking metformin. However, it is generally recommended to eat a healthy diet that is low in fat, sugar, and calories in order to prevent high blood sugar. This type of diet can help you control your blood sugar levels and lose weight. Focus on meal plans that include eating healthy foods that can raise your blood sugar levels like:

  • Fruits – such as apples, oranges, bananas, and grapes
  • Nonstarchy vegetables such as broccoli, carrots, and leafy greens
  • Complex carbs (carbohydrates) such as oatmeal, whole grain bread, and brown rice, which are high in fiber
  • Legumes – such as beans, and lentils
  • Lean protein – such as chicken, fish, tofu, and beans
  • Healthy fats – such as olive oil, avocados, nuts, and seeds that may help to reduce your risk of a cardiovascular events, including stroke and heart attack

Foods to eat when taking metformin for weight loss

The best advice as with all meals is to maintain a healthy balanced diet, high in protein, and low in fat and carbs. Use whole foods, fruits, vegetables, and grains, and reduce how much processed food you consume.

Metformin and eggs

Eggs are a protein-rich food and that help to manage blood sugar levels in people with diabetes.

Can you eat bananas with metformin?

Bananas contains a combination of carbs that can raise blood sugar, and also beneficial fiber nutrients. The advice is to eat no more than 2 to 3 bananas in a week if you are diabetic.

What to eat for breakfast while taking metformin

Some options for breakfast if you are taking metformin are whole-grain cereal with oatmeal, egg, and flaxseed, or bagels with nut butter, banana, and chia seeds.

Can you drink milk while taking metformin?

You can drink milk with metformin, but to reduce the side effects of diarrhea you are advised to drink either semi-skimmed or low fat milk rather than full fat milk to help limit your carb intake.

Metformin drug interactions

Metformin can interact with other medications. These include:

  • Antibiotics
  • Diuretics
  • NSAIDs
  • Corticosteroids
  • Treatments for heart failure and high blood pressure
  • Contraceptive pills also affect blood sugar levels so a change in dosage may be required
  • Antipsychotics
  • Anticonvulsants
  • Blood thinners
  • Other diabetes drugs

Metformin can interact with other medications. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Metformin contraindications

You should not use metformin if you:

  • Are allergic to metformin
  • Have severe kidney disease
  • Have metabolic acidosis or diabetic ketoacidosis
  • Are younger than 10 years old
  • Are breastfeeding or are planning to breastfeed

Talk to a healthcare professional before using metformin if you:

  • Have kidney disease
  • Have high ketone levels in your blood or urine
  • Have heart disease, or congestive heart failure
  • Have liver disease
  • Use insulin or other oral diabetes medications
  • Have a severe infection
  • Have chronic alcoholism
  • Are 65 or older
  • Are pregnant or are planning to become pregnant

Who can take metformin?

Metformin is typically prescribed to people with type 2 diabetes. Metformin may not be the right diabetes medication for you if you have certain medical conditions or other risk factors that may affect your health. Talk with your doctor about your health history before taking metformin.

For individuals with diabetes, it is important to monitor low blood sugar to prevent symptoms of hypoglycemia (low blood sugar).

Can I take Ozempic with metformin?

Ozempic and metformin are safe to take together and are often prescribed together for the treatment of type 2 diabetes and weight management.

Speak to your healthcare provider if you are taking any other prescription medications, over-the-counter medications, or supplements while taking metformin.

How long does Trulicity stay in your system?

Type 2 diabetes mellitus affects over 6% of the population, causing people suffering from this condition to be more susceptible to other health risk factors such as kidney and heart disease.

Trulicity is a relatively new treatment for diabetes. In this article, we will answer questions commonly asked about Trulicity, such as what is Trulicity, how does Trulicity work, how long will Trulicity stay in your system, what are Trulicity’s long-term effects and side effects, and other useful information to know when using Trulicity.

What is Trulicity?

Trulicity is the brand name for an FDA-approved diabetes medication manufactured by Eli Lilly and Company. It is used with diet and exercise to lower blood sugar levels in adults with type 2 diabetes. Trulicity contains dulaglutide as the active ingredient and belongs to a class of drugs known as GLP-1 receptor agonists (glucagon-like peptide 1).

What is Trulicity used for?

Trulicity is used in adults who have type 2 diabetes to:

  • Reduce high blood sugar levels, when used alongside exercise and diet changes
  • Reduce the risk of serious cardiovascular events, like strokes or heart attacks, in people with heart disease, or reduce the risk factors for heart problems. Examples of risk factors for an increased risk of cardiovascular disease include high cholesterol, being elderly, having high blood pressure, and smoking

Trulicity is not approved by the FDA for the treatment of type 1 diabetes, weight loss. Currently, the only GLP-1 agonists approved for weight loss are Wegovy (semaglutide) and Saxenda (liraglutide).

RELATED: What is Trulicity

How does Trulicity work?

If you have type 2 diabetes, you may not produce enough insulin, or you may even become resistant to insulin. If this happens, you will absorb less sugar from your blood, resulting in your blood glucose levels remaining too high.

The active ingredient dulaglutide in Trulicity is classed as a GLP-1 receptor agonist (glucagon-like peptide 1), which can lower your A1C levels. It is absorbed into your digestive system where it has two effects. It binds with areas on some of your cells called GLP1R receptors, This encourages your pancreas to make more insulin and allows other cells in your body to more effectively remove sugar from your blood. At the same time, dulaglutide also reduces how much sugar your pancreas secretes into your blood. The combination of these two processes can reduce your blood sugar levels.

What is the recommended dosage of Trulicity?

Trulicity is available in injection form, in the following doses: 0.75 mg/0.5 mL solution in a single-dose prefilled Trulicity pen, and 1.5 mg/0.5 mL solution in a single-dose prefilled Trulicity pen.

RELATED: Trulicity Dosage

How should you take Trulicity?

Use Trulicity as a subcutaneous injection in the abdomen, thigh, or upper arm as a weekly dose at any time of the day. Initiate treatment with Trulicity at 0.75 mg once weekly. Your dose of Trulicity can be increased to 1.5 mg once weekly for additional glycemic control.

If you miss a dose it should be taken as soon as you remember. If less than 3 days (72 hours) remain before your next scheduled dose, skip the missed dose and take your next dose on the regular scheduled day.

Your healthcare provider may prescribe Trulicity in combination with other diabetes medications such as metformin and empagliflozin. Please see the full drug information and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How long does it take for Trulicity to work?

This will differ from person to person, but usually it will take around 4 weeks before you start to see a change in blood sugar levels. The full benefits of using Trulicity may take longer.

How long does Trulicity stay in your system?

The half-life for both 0.75mg and 1.5mg doses of Trulicity is approximately 5 days. It will take 27 to 30 days for Trulicity to completely leave your system.

When should you stop taking Trulicity?

Discontinue using Trulicity if you develop pancreatitis or if you have a serious allergic reaction when using this medication. Speak to your healthcare provider for medical advice if this occurs.

What happens if you stop using Trulicity?

Stopping Trulicity treatment suddenly does not cause withdrawal symptoms, but your blood sugar levels may rise. Speak to your doctor for medical advice before discontinuing this medication.

How long does it take for the effects of Trulicity to wear off?

You may continue to see the effects of Trulicity for up to 27 to 30 days after your final dose.

Can you take Trulicity every other week?

Trulicity is designed to be used once per week on the same day each week. If you miss a dose of Trulicity, and it’s at least 3 days before your next dose, take the missed dose. If less than 3 days remain before your next dose, skip the missed dose and take your next dose on the regular scheduled day.

Do you regain weight after stopping Trulicity?

People taking Ozempic, a medication that belongs to the same class of drug as Trulicity showed that those who lost the most weight while using it, gained the most after stopping treatment.

What does Trulicity do to your body?

Trulicity reduces your blood sugar levels by stimulating your pancreas to release insulin, which will stimulate the uptake of glucose into cells.

What are the side effects of Trulicity?

The most common side effects of Trulicity in clinical trials compared to placebo include:

  • Injection-site reactions like swelling, pain, or itching
  • Nausea, vomiting
  • Gastrointestinal side effects include diarrhea, constipation, and abdominal pain
  • Reduced appetite

Do not take more Trulicity than recommended. Taking more than the recommended may lead to serious side effects. More serious side effects of Trulicity include:

  • Severe allergic reactions to the medication such as anaphylaxis or shortness of breath
  • Thyroid tumors and a type of thyroid cancer called medullary thyroid carcinoma
  • Inflammation of your pancreas (pancreatitis)
  • Kidney problems, including kidney failure
  • Increased heart rate
  • Hypoglycemia (low blood sugar) particularly when used with other medications like insulin or sulfonylurea
  • Severe stomach problems
  • Changes in your vision

If you do experience any serious side effects, stop taking Trulicity and seek medical attention immediately. You are encouraged to report negative adverse events of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

RELATED: Trulicity side effects and how to avoid them

How long do Trulicity side effects last?

Some patients experienced the side effect of nausea within the first 2 to 3 days after their first dose. This side effect generally lasted 2 weeks but may continue in some patients after the 2nd week of treatment.

What are the risks of long-term use of Trulicity?

Discuss your medical history with your doctor before starting treatment with Trulicity, as treatment with Trulicity may worsen certain conditions.

  • Trulicity may cause new or worsening kidney disease, including kidney failure. Be careful to not become dehydrated while using Trulicity as this could also cause kidney problems
  • You may have an allergic reaction to Trulicity. You will have to stop treatment if you have allergic reactions to Trulicity or any of its other ingredients. Tell your doctor if you have previously had an allergic reaction to medications such as Ozempic which belongs to the same class of drugs as Trulicity
  • Trulicity may make a condition known as diabetic retinopathy worse. Make sure you monitor yourself for any changes in your vision
  • Acute and chronic pancreatitis (inflammation of the pancreas) have been reported in clinical studies. Report any symptoms of pancreatitis, including persistent severe stomach pain which sometimes radiates to the back
  • Your risk of hypoglycemia (low blood sugar) is increased if Trulicity is used in combination with an insulin secretagogue (sulfonylurea) or insulin. Your dosage of other treatments may need to be adjusted
  • Trulicity may cause thyroid C-cell tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC). See the boxed warning for Trulicity and speak to your healthcare provider if you get swelling in your neck, hoarseness, difficulty swallowing, or shortness of breath. Tell your doctor if you have a family history of MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2
  • Tell your doctor if you are pregnant or breastfeeding. Trulicity shouldn’t be used during pregnancy and for at least two months before a planned pregnancy because it is not known if it may affect your unborn child

Drug interactions may occur with Trulicity, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your healthcare provider about all of your medications including any supplements you are taking.

Side effects of Myrbetriq in the elderly

Historically, antimuscarinic drugs, such as Vesicare (oxybutynin), Detrol (tolterodine) and anticholinergic drugs, have been used to treat overactive bladder (OAB). However, these therapies have been shown to have side effects, such as dry mouth, drowsiness, constipation, dizziness, and confusion, as well as an increase in the risk of cognitive impairment and dementia, a side effect of considerable concern in older people.

Myrbetriq is the brand-name for an alternative treatment option manufactured by Astellas Pharma US, Inc. While Myrbetriq is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Myrbetriq include urinary tract infections, nausea, and headaches. Less common, but more serious side effects, can include irregular heartbeats, and palpitations.

Learn more about the side effects of Myrbetriq in the elderly and how to avoid them.

What is Myrbetriq (mirabegron)?

Myrbetriq contains mirabegron, a beta-3 adrenergic agonist as the active ingredient. It is used to treat an overactive bladder in adults. An overactive bladder is a condition where you feel the need to urinate often and sometimes suddenly. You may feel a combination of needing to urinate often (increased urinary frequency), needing to urinate suddenly (urinary urgency), or losing control of when you want to urinate (urinary incontinence). It is also used to treat neurogenic detrusor overactivity (NDO).

Mirabegron relaxes the muscles in the wall of your bladder (detrusor urinae muscle) helping to reduce the symptoms of an overactive bladder. It does this by attaching itself to areas on the surface of the muscles called β3-adrenergic receptors. These receptors are stimulated by mirabegron, starting a process that relaxes the bladder muscles.

Myrbetriq dosage

Myrbetriq is available as 25 mg and 50 mg extended-release tablets.

The recommended starting dose of Myrbetriq is 25 mg once daily, alone or in combination with solifenacin succinate (Vesicare) 5 mg, once daily. Your dose of Myrbetriq may be increased to 50 mg once daily, based on its effectiveness and your ability to tolerate it.

Swallow the tablets whole with water, with or without food, do not chew, divide or crush. If you miss a dose, take the missed dose as soon as possible. If however, it’s been 12 hours or more since your dose was supposed to be taken, skip it and take the next dose at the normal time. Store Myrbetriq at room temperature, away from heat, moisture, and direct light.

Please read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How effective is Myrbetriq?

Myrbetriq is FDA (Food and Drug Administration)-approved for the treatment of an overactive bladder. Approval is based on clinical studies, where Myrbetriq effectively treated symptoms of an overactive bladder within four to eight weeks, depending on the dosage.

What are the side effects of Myrbetriq in the elderly?

The most common side effects of Myrbetriq in clinical trials, compared to placebo include:

  • Hypertension
  • Nasopharyngitis
  • Urinary tract infection (UTI)
  • Headache, dizziness, nausea
  • Fast heartbeat (tachycardia)
  • Constipation, diarrhea
  • Back pain
  • Dry mouth

Myrbetriq can cause more serious side effects, including:

  • Irregular heartbeat (atrial fibrillation), palpitations, affecting around 1 in 100 people
  • Severe rise in blood pressure (hypertensive crisis), affecting around 1 in 1,000 people

If you experience any of these serious side effects, stop taking Myrbetriq and seek medical attention immediately. You are encouraged to report negative adverse events of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Myrbetriq drug interactions

Myrbetriq can interact with other medications including:

  • Treatments for abnormal heart rhythm – propafenone or flecainide
  • Beta-blockers – carvedilol, propranolol, metoprolol, timolol
  • Drugs metabolized By CYP2D6 – desipramine
  • Digoxin
  • Other medications for an abnormal heart rhythm – quinidine, sotalol, procainamide, ibutilide, flecainide, dofetilide, or amiodarone
  • Certain blood thinners, such as warfarin, dabigatran etexilate
  • Antipsychotic medicines – thioridazine, mesoridazine, haloperidol, or chlorpromazine
  • Medications for allergic rhinitis

Before taking Myrbetriq, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Myrbetriq warnings & precautions

Don’t take Myrbetriq if:

  • Are allergic to the active ingredient mirabegron
  • Have had an allergic reaction to any of the other ingredients in Myrbetriq
  • If you have high blood pressure that is not controlled
  • Are under 18 years of age
  • Are pregnant or trying to become pregnant

Talk to your doctor before taking Myrbetriq if you:

  • Take any other medications for an overactive bladder
  • Have glaucoma
  • Have other bladder problems (such as blockage)
  • Have trouble emptying your bladder or have a weak urine stream
  • Have any liver problems or kidney problems
  • Have an ECG (heart tracing) abnormality called QT prolongation
  • Are breastfeeding or plan to breastfeed – It is unknown if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Myrbetriq, to make sure it is safe for you.

Other warnings you should know about

  • Myrbetriq may increase your risk of urinary retention (trouble passing urine or not fully emptying the bladder), especially when used with another medicine (solifenacin succinate)
  • Urinary retention has also been reported in patients with bladder outlet obstruction (BOO)
  • Serious allergic reactions, called angioedema, which can be life-threatening and requires immediate medical attention have been reported. Stop treatment and get emergency medical help if you have signs of an allergic reaction (hives, trouble breathing, swelling of your face, lips, tongue, or throat)

How to avoid Myrbetriq side effects in the elderly

The best way to avoid side effects in older adults is to take Myrbetriq as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Myrbetriq that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Drink plenty of fluids

If you have diarrhea with Myrbetriq may make you lose more fluids than usual if you have diarrhea. Drink plenty of fluids to avoid getting dehydrated.

3. Avoid alcohol

Alcohol does not affect how mirabegron works. Alcohol however can make your symptoms of urinary frequency and urgency worse.

4. Know the signs and symptoms of Myrbetriq side effects

Signs and symptoms of side effects include hypertension, nasopharyngitis, and urinary tract infection. If you experience any of these symptoms talk to your doctor.

5. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with Myrbetriq.

6. Get regular medical checkups

If you have an overactive bladder it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Myrbetriq as needed.

Side effects of Eliquis in the elderly

Eliquis is a brand-name medication manufactured by Bristol-Myers Squibb. It is an anticoagulant used to prevent blood clots from forming in the body. While Eliquis is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Eliquis include an increased risk of bleeding and bruising. Less common, but more serious side effects, can include allergic reactions.

Learn more about the side effects of Eliquis in the elderly and what you can do to avoid them.

What is Eliquis (apixaban)?

Eliquis is an anticoagulant, a type of drug that stops blood clotting. The medication is used to prevent blood clots from forming in people who have:

  • Nonvalvular atrial fibrillation (an irregular heartbeat not caused by a heart valve problem) and who have other clotting risk factors
  • Had hip or knee replacement surgery

It’s also used to treat blood clots in your legs (deep vein thrombosis) and lungs (pulmonary embolism), and to stop blood clots from reoccurring in these places.

Blood clotting is a normal process that happens when you’re injured. If you cut yourself, a clot forms to seal the cut to stop you from losing any more blood. But sometimes blood can clot inside your body where it shouldn’t, and this can cause problems. Clots can block the flow of blood, starving parts of the body of oxygen, and damaging tissues. Depending on where blood clots form, they can cause deep vein thrombosis, heart attacks, and strokes. Sometimes Eliquis is called a blood thinner, as it helps to lower the chances of blood clots forming.

The active ingredient in Eliquis is an anticoagulant called apixaban. As blood clots, it goes through a process of chemical reactions that turn it from a liquid into a thick gel. An enzyme called factor Xa is an important part of this process. Apixaban is a factor Xa inhibitor and attaches to factor Xa to stop it from working, reducing the likelihood of blood clots forming.

RELATED: What is Eliquis

Eliquis dosage

Eliquis is available in tablet form, in the following doses: 2.5 mg and 5 mg.

The recommended dose of Eliquis is 5 mg orally twice daily. For elderly patients 80 years of age or older, weighing 60 kg or less, or having serum creatinine equal to or above 1.5 mg/dL, the recommended dose is 2.5 mg orally twice daily.

If you are unable to swallow the tablets whole, you may crush them and mix with water, apple juice, or applesauce and taken orally. Crushed tablets may also be mixed with 60 mL of water and given through a nasogastric tube.

If you take heparin, warfarin, Coumadin, or Jantoven, your doctor will give you instructions about how to switch to apixaban. You do not need to monitor your Vitamin K intake while taking Eliquis. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the normal time.

You are advised to read the medication guide provided with this medicine for the full drug information, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

RELATED: Eliquis Dosage

Why are blood thinners prescribed to the elderly?

Older adults may be more likely to have medical conditions needing them to use blood thinners. Conditions may include:

  • Nonvalvular atrial fibrillation – causes disruption to the flow of blood and increases the risk of blood clots
  • Deep vein thrombosis (DVT) – blood clots occur deep within a vein, most commonly in a thigh or lower leg
  • Pulmonary embolism – when a DVT blood clot breaks free from where it initially formed and travels along to the pulmonary arteries in the lungs. Symptoms may include chest pain, and difficulty breathing
  • Coronary artery disease – arteries in the heart become narrowed or blocked entirely
  • Peripheral artery disease – arteries in the head, arms, and legs become narrowed
  • Elderly patients requiring knee or hip surgery are more likely to develop blood clots after surgery

What are the side effects of Eliquis in the elderly?

The most common side effects of Eliquis in clinical trials include:

  • Increased bleeding risk – anemia, increased bruising, bloody or brown urine or bloody or tarry stools, bleeding from your anus or vagina, vomiting blood or what appears to look like dark coffee grounds, unusual nosebleeds
  • Headache, dizziness, weakness, pain, swelling, or discomfort in a joint
  • Pinpoint red spots on your skin

Eliquis can cause more serious side effects, including:

  • Serious, potentially fatal bleeding
  • Hypersensitivity reactions including anaphylactic allergic reactions. This is a medical emergency. Call your doctor right away if you develop a skin rash, itching, trouble breathing, difficulty swallowing, or any swelling of your hands, face, or mouth
  • Thrombocytopenia (including platelet count decreases)
  • Hypotension
  • Epistaxis
  • Gastrointestinal hemorrhage (bleeding)
  • Abnormal liver function tests
  • Incision-site hematoma

If you experience any serious side effects, stop taking Eliquis and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Eliquis drug interactions

Elderly patients usually take medicines for other medical conditions and will require close monitoring. Eliquis can interact with other medications including:

  • Antifungal medicines – ketoconazole, voriconazole
  • Other drugs used to prevent blood clotting – dabigatran, rivaroxaban (Xarelto)
  • Antiplatelets – clopidogrel
  • Oral anticoagulants – warfarin
  • NSAIDs (nonsteroidal anti-inflammatory drugs) – diclofenac, ibuprofen, meloxicam
  • Medicines for high blood pressure or heart problems – amlodipine, felodipine
  • Antidepressants – citalopram, escitalopram, fluoxetine
  • Treatments for seizures – carbamazepine, phenobarbital, phenytoin
  • St John’s Wort

Before taking Eliquis, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Eliquis warnings & precautions

Don’t take Eliquis if you:

  • Are allergic to the active ingredient apixaban
  • Are allergic to any of the other ingredients found in Eliquis
  • Have artificial heart valves
  • Have antiphospholipid syndrome (APS), especially with positive triple antibody testing, and have a history of blood clots
  • Are under 18 years of age
  • Are bleeding excessively
  • Have an organ condition that increases the likelihood of serious internal bleeding, like a stomach ulcer

Talk to your doctor before taking Eliquis if you:

  • Have an increased risk of bleeding, such as a bleeding disorder or very high blood pressure
  • Are over 75 years of age
  • Weigh 60kg or less
  • Have a severe kidney disease or are on dialysis
  • Have a liver problem or a history of liver problems
  • Have antiphospholipid syndrome
  • Are lactose intolerant
  • Need to have surgery or another procedure that can cause bleeding
  • You are pregnant or breastfeeding

You should always check with your doctor or pharmacist before taking any medication, including Eliquis, to make sure it is safe for you.

Other warnings you should know about

  • Eliquis may need to be temporarily stopped a few days before surgery of any sort, including dental procedures
  • Speak to your doctor before you stop using this medicine. There may be a higher risk of stroke if you stop using this medicine suddenly.
  • Grapefruit juice may increase the amount of Eliquis in your body. Talk with your health care provider or pharmacist if grapefruit is part of your diet
  • Eliquis may increase the risk of blood clots in the epidural area or spine. The risk of this occurring increases if an epidural catheter has been previously placed in your back prior to treatment with Eliquis, if NSAIDs or anticoagulants are being taken, if you have previously had punctures in the epidural area or any other issues with your spine, or if you have had surgery in the past on your spine. Symptoms may include a tingling sensation, feeling numb, or muscle weakness, specifically in your feet or legs.

How to avoid Eliquis side effects in the elderly

The best way to avoid side effects is to take Eliquis as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Eliquis that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Know the signs and symptoms of Eliquis side effects

Signs and symptoms of side effects include an increased risk of bleeding and bruising. If you experience any of these symptoms call your doctor for medical advice.

3. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Eliquis.

4. Get regular medical check ups

If you have side effects it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Eliquis as needed.

Side effects of Xarelto in the elderly

Xarelto is a brand-name medication manufactured by Janssen Pharmaceuticals, Inc. It is classed as an oral anticoagulant and used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). While Xarelto is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Xarelto include indigestion, muscle pain, and diarrhea. Less common, but more serious side effects, can include severe allergic reactions and an increased risk of bleeding.

Learn more about the side effects of Xarelto in the elderly and what you can do to avoid them.

What is Xarelto (rivaroxaban)?

Xarelto (rivaroxaban) is an FDA-approved (Food and Drug Administration) prescription blood thinner (anticoagulant) medication used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). It’s used to reduce the risk of DVT and PE recurring. Xarelto belongs to a class of medications called Factor Xa inhibitors which reduce the chance of blood clots happening and also reduce the risk of coronary heart disease and peripheral artery disease. It’s prescribed specifically to:

  • Reduce the chances of a blood clot forming in people who have a condition called atrial fibrillation (if it’s not caused by a heart valve problem)
  • Reduce the chances of a blood clot forming and causing deep vein thrombosis or a pulmonary embolism
  • Reduce the chances of a blood clot forming again in people who are at risk of blood clots after having been treated for them for at least six months
  • Reduce the chances of a blood clot forming in people who have had knee replacement surgery
  • Reduce the chances of a blood clot forming in people who have reduced mobility and may lie or sit still for long periods. This is usually after someone is hospitalized for an acute illness or major surgery, and as they recuperate after they’ve been discharged
  • Reduce the risk of serious cardiovascular problems, heart attacks, or strokes in people with coronary artery disease
  • Reduce the risk of serious heart problems, heart attacks, or strokes in people with peripheral artery disease

You may also be prescribed Xarelto if you have coronary artery disease or peripheral artery disease. The active ingredient in Xarelto is called rivaroxaban. It’s an anticoagulant drug, also called a blood thinner, that reduces the likelihood of clots forming in your blood.

When you take Xarelto, rivaroxaban is absorbed into your blood. It attaches itself to and blocks an enzyme in your blood, called Factor Xa. This enzyme controls a step in the clotting process, and by blocking it, rivaroxaban makes it less likely your blood will clot.

Always check with your doctor or pharmacist before taking any medication, including Xarelto, to make sure it is safe for you.

Why are blood thinners prescribed to elderly patients?

Older adults may be more likely to have medical conditions that may need them to take Xarelto. Conditions may include:

  • Nonvalvular atrial fibrillation
  • Deep vein thrombosis (DVT)
  • Pulmonary embolism
  • Coronary artery disease – can cause an increased risk of stroke or heart attack
  • Peripheral artery disease
  • Knee or hip replacement surgery

Xarelto dosage

Xarelto is available in two different oral tablet strengths:

  • Xarelto 2.5mg – white, oblong-shaped tablets with “BAYER” on one side and “2.5” on the other side.
  • Xarelto 10mg – white, round tablets with “BAYER” on one side and “10” on the other side.
  • Xarelto 15 mg – these are white, round tablets debossed with “15” on one side and plain on the other side.
  • Xarelto 20 mg – these are yellow, round tablets debossed with “20” on one side and plain on the other side.

For additional safety information, read the full prescribing information and medication guide. Always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

What are the side effects of Xarelto in the elderly?

The most common side effects of Xarelto in clinical trials include:

  • Nosebleeds
  • Indigestion
  • Muscle pain
  • Stomach pain or discomfort
  • Diarrhea

Xarelto can cause more serious side effects, especially for older patients including:

  • Severe allergic reactions to the medication
  • An increased bleeding risk that won’t stop, like a hemorrhage (bleeding from a ruptured blood vessel)
  • An increased risk of spinal or epidural hematoma (bleeding and blood clots in your spine) in patients who take Xarelto and who receive a spinal puncture or local anesthetic injection around their spine – this could result in paralysis
  • Liver damage and hepatitis (inflammation in your liver) 

If you experience any of these serious side effects, stop taking Xarelto and seek medical attention immediately. Serious side effects may indicate gastrointestinal bleeding, and intracranial hemorrhage (bleeding in the brain). These types of bleeding incidences are more common in elderly patients. You are encouraged to report adverse events of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Xarelto drug interactions

Xarelto can interact with other medications including:

  • Any other oral anticoagulants such as apixaban, dabigatran, or rivaroxaban
  • Aspirin or aspirin-containing products
  • Non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or naproxen
  • Any other medications or supplements that can increase your risk of bleeding, including any medications that contain warfarin or heparin
  • Any selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants
  • Any medications taken to treat fungal infections, particularly ketoconazole
  • Any antibiotics taken to treat a bacterial infection, particularly erythromycin or rifampicin
  • Any HIV/AIDS medications, particularly ritonavir
  • Any medications taken to treat seizures, particularly phenytoin or carbamazepine
  • An herbal supplement called St John’s Wort

Before taking Xarelto, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Xarelto warnings & precautions

You should not take Xarelto if you have certain risk factors such as if you:

  • Are allergic to rivaroxaban or any other ingredients in the medication
  • Are pregnant or planning to become pregnant
  • Are breastfeeding or planning to breastfeed
  • Have had a recent spinal puncture or epidural catheter placement
  • Have an active internal bleeding disorder

Talk to your doctor before taking Xarelto if you:

  • Have or have had bleeding problems
  • Have liver disease
  • Have renal impairment
  • Are scheduled to have surgery
  • Are 65 years of age or older
  • Are taking any medications that could increase your risk of bleeding, including any medications that contain warfarin or heparin
  • Are taking any SSRI or SNRI antidepressants
  • Are taking any medications

You should always check with your doctor or pharmacist before taking any medication, including Xarelto, to make sure it is safe for you.

The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural /spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, blood thinners P2Y 12 platelet inhibitors, dual antiplatelet therapy, other antithrombotic agents, fibrinolytic therapy, NSAIDs, selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs). Elderly patients may be at higher risk of bleeding if they take Xarelto and have certain other medical problems.

Other warnings you should know about

Stopping Xarelto suddenly can increase the risk of a blood clot blocking a vein or artery. The manufacturer advises a different blood thinner to be taken if Xarelto needs to be stopped for any reason other than major bleeding events. This will help ensure you do not experience potentially life-threatening blood clots.

The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural /spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, blood thinners P2Y 12 platelet inhibitors, dual antiplatelet therapy, other antithrombotic agents, fibrinolytic therapy, NSAIDs, selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs). Elderly patients may be at high risk of bleeding, back pain, and weakness if they take Xarelto and have certain other medical problems.

How to avoid Xarelto side effects in the elderly

The best way to avoid side effects is to take Xarelto as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Xarelto that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Know the signs and symptoms of Xarelto side effects

Signs and symptoms of side effects include indigestion, diarrhea, and muscle pain. If you experience any of these symptoms call your doctor for medical advice.

3. Monitor your weight

Xarelto should not affect your body weight.

4. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Xarelto.

5. Get regular medical check ups

If you have side effects it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Xarelto as needed.

Healthcare Costs

The states paying the most for healthcare

The cost of living crisis has hit America hard, leaving citizens struggling financially and unable to afford the basic necessities of food, fuel, utilities, and healthcare.

With prescription drug charges already two to three times higher than in other countries, and with insurance costs and prescription medication charges rapidly increasing, many Americans are left unable to afford life-saving medications like Eliquis, Xarelto, Creon and Jardiance.

But which states are paying the most for their healthcare? We’ve taken a look at overall healthcare costs and the average price of prescription medications in each state to find out. We’ve also examined the injuries and illnesses Americans pay the highest premiums for.

The states paying the most for healthcare

 

1. Alaska

$11,064 per person

Taking the top spot is Alaska with overall medical spending per person totaling more than $11,000. Medical costs in Alaska are the highest in the nation thanks to its tiny population and isolation from the mainland US and larger healthcare markets. This means limited competition between healthcare providers and higher healthcare costs.

2. Massachusetts

$10,559 per person

Up next is The Bay State, with residents paying more than $10,500 per person for their healthcare. The state previously introduced landmark legislation to curb healthcare costs, although even with these measures health insurance for a family of four costs an average of $22,000.

3. Delaware

$10,254 per person

Delaware takes third place, with residents forking out $10,254 per person in overall healthcare costs. The consolidation of hospitals and healthcare systems in the state has created a lack of competition, meaning hospitals aren’t incentivized to offer insurers lower prices.

 

Overall healthcare costs by state

 

 

States paying the most for prescription medicine

 

1. Rhode Island

Average prescription cost: $288.37

The New England state tops the list for medication charges. Recently the state has introduced measures to cap prices on certain essential medications for chronic diseases like insulin, although the average price of prescription medications is still the nation’s highest, at just over $288. 

2. Massachusetts

Average prescription cost: $268.21

Up next is Massachusetts. Similarly to other states, Massachusetts has recently introduced laws to punish drug companies for overcharging their customers, capping their ability to profit at 20 percent above the index price of drugs like Linzess. However, this still leaves its residents paying an average of $268.21 per prescription.

3. North Dakota

Average prescription cost: $222.36

With the price of prescription drugs in the US outpacing inflation, as many as one in four North Dakotans didn’t fill a prescription over the past two years, citing rising costs as the key reason. The Peace Garden State takes third place, with medication costs averaging slightly more than $222 per prescription.

Average cost of medication by state

 

Of course, there are many different costs associated with illness and injuries including travel, childcare, and loss of working hours when seeking out healthcare too. But which will cost the most for an ER visit? Here are the most expensive common injuries and illnesses.

 

Most costly injuries and illnesses

 

1. Kidney stones

Average cost: $4,247

This painful and often hereditary condition triggered by a poor diet or other medical complaints like past infections takes the top spot, costing over $4000 to treat. Kidney stones are the most expensive illness as they have a high chance of recurring and are becoming an increasingly common medical complaint, pushing costs up.

2. Urinary tract infections

Average cost: $2,598

This ailment, one of the most common reasons for women to attend primary care, takes second place. Urinary tract infections, which when left untreated can cause kidney infections, cost an average of more than $2,500 per person, including diagnosis and a prescription for antibiotics. 

3. Intestinal infections

Average cost: $2,398

Taking third place are intestinal infections. This illness costs an average of $2,398, with the condition becoming more expensive to treat as severe cases are increasing, leading to more people being hospitalized and visiting ER departments for treatment.

Methodology

The states paying the most for healthcare: The overall healthcare costs in each state according to World Population Review.

The states paying the most for prescription medication: The average cost of prescription medication in each state, calculated by dividing the total number of prescriptions by the total prescription charges in each state according to Definitive Healthcare.

The most costly injuries and illnesses: The average cost of a doctor’s visit without insurance for selected medical complaints according to VisaGuide.

 

Alcohol Across the US

Which States Have the Most Binge Drinkers & Alcohol Deaths?

Despite the fact that the legal drinking age in the US is 21, many people in the US aged 18 and over either regularly drink or have consumed alcohol at some point during their life. For many, it’s the social aspect that has integrated this habit as an essential part of their life. However, for many others, there is a certain level of dependency on it.

In 2019 the National Institute on Alcohol Abuse and Alcoholism reported that 25.8% of people aged 18 and up, had engaged in binge drinking within the last month. A further 6.3% of people in the same age group had engaged in heavy alcohol use in the past month. They also stated roughly 95,000 people die from alcohol-related causes annually, making it the third-highest cause of preventable death in the US.

But, where in the US has the highest number of binge drinkers and alcohol-related casualties? We at NiceRx have analyzed data to answer just that, and we’ve also looked at the dangers of excessive drinking.

 

Most binge drinkers across states

1. New Hampshire

Alcohol Consumption per Capita 2022: 4.67 gallons

New Hampshire, located in New England, which is in the northeastern region of the United States, comes out as the state with the highest alcohol consumption per capita. It is one of the smallest and least populous states, yet despite this, managed 4.67 gallons per capita. According to the CDC a beer is 12 ounces and a glass of wine is 5 ounces. This means New Hampshire drank around 62 beers or 149 glasses of wine per capita in 2022. 

2. Delaware       

Alcohol Consumption per Capita 2022: 3.52 gallons

Delaware is a small Mid-Atlantic state, located on the east coast of the United States. In fact, it is the second-smallest state in the US and the sixth-least populous. Having drank significantly less than New Hampshire per capita during 2022, Delaware still managed 3.52 gallons per capita. Which is still 108 glasses of wine and 45 beers, by the CDC’s count.

3. Nevada          

Alcohol Consumption per Capita 2022: 3.42 gallons

Located in the West of the United States and sharing a border with California, we have Nevada, home of the Las Vegas Strip, a stretch of road known for gambling and drinking. Nevada is the seventh most extensive state, yet only the thirty-second most populous, meaning it has a low population density. In 2022, the state recorded an alcohol consumption of 3.42 gallons per capita, just a little less than Delaware.

4. North Dakota

Alcohol Consumption per Capita 2022: 3.16 gallons 

North Dakota is located in the Upper Midwest, along the Canadian border of Saskatchewan and Manitoba to the north. It is the 19th largest state, but it is the fourth-least populous, as well as the fourth-most sparsely populated state. 3.16 gallons per capita is what the state recorded for 2022, which comes out at around 97 glasses of wine and 40 beers.

5. Montana

Alcohol Consumption per Capita 2022: 3.1 gallons

Taking the fifth spot for states with the highest alcohol consumption, we have Montana, located in the Mountain West sub-region of the United States and borders North and South Dakota. Once again, this is a state with a lower population density. It’s the fourth-largest state, but the eighth-least populous. In 2022, the state consumed 3.1 gallons of alcohol, per capita. That’s exactly 39.7 beers and 95 glasses of wine, again, per capita.

us states with most binge drinkers

States with highest alcohol cost

The costs referred to in this section are primarily comprised of, loss of workplace productivity, health care expenses, property damage, motor vehicle crash costs and criminal justice expenses.

1. Alaska

Total Cost of Excessive Alcohol Consumption: $827,200,000

Cost per Drink: $2.25

Cost per Capita: $1,165

Alaska is a semi-enclave state, bordering the Canadian province of British Columbia, and is by far the largest state by area, beating even Texas. However, it is also the third-least populous state and the most sparsely populated. The total cost of excessive drinking in Alaska is $827.2 million, which works out at $1,165 per person living in the state.

2. New Mexico

Total Cost of Excessive Alcohol Consumption: $2,232,900,000

Cost per Drink: $2.77

Cost per Capita:$1,084

Located in the Southwestern region of the United States, along the Mexican border, we have New Mexico, the state with the second highest cost for excessive alcohol consumption. The total cost of excessive alcohol consumption for the state was $2.23 billion, which is $1,084 per person.

3. Wyoming

Total Cost of Excessive Alcohol Consumption: $593,100,000

Cost per Drink: $2.33

Cost per Capita: $1,052

Wyoming is located in the Mountain West sub-region of the Western United States and it shares borders with six other states. Despite being the tenth largest state in the US, it is the least populous state. The total cost of excessive drinking in Wyoming was $593.1 million or $1,052 per person.

4. Colorado

Total Cost of Excessive Alcohol Consumption: $5,056,500,000

Cost per Drink: $2.14

Cost per Capita: $1,005

Another state located in the Mountain West sub-region of the United States, we have Colorado, home of the Rocky Mountains. It is the eighth most expensive state and the 21st most populous. Colorado also ranked in the top ten for alcohol consumption, at 2.88 gallons per person for 2022. The cost of excessive alcohol consumption is $1,005 per person, making it the state with the fourth-highest cost. 

5. California

Total Cost of Excessive Alcohol Consumption: $35,010,600,000

Cost per Drink: $2.44

Cost per Capita: $940

Rounding out the top five, we have California, which lies on the West coast of the United States. It is the third largest state by area and by far the most populous. Despite ranking only 22nd for alcohol consumption levels per capita in 2022, it has the largest total excessive alcohol consumption cost, at $35 billion. However, per capita, it is just $904 making it the state with the fifth-highest cost.

All states most spent on alcohol

States with most alcohol related deaths

1. New Mexico

Average Death Rate per 100,000 People (2019): 34.3

New Mexico, having already ranked high for its cost of excessive alcohol consumption, has the highest alcohol-related death rate. Their total death rate for 2019, for alcohol-related deaths, was 34.3 per 100,000. 

2. Wyoming

Average Death Rate per 100,000 People (2019): 28.5

Wyoming also ranked well for the highest excessive alcohol consumption costs, placing in the top three and now it takes second for the highest alcohol-related death rate. In 2019, the state recorded a 28.5 death rate per 100,000 of the population, for deaths caused by alcohol consumption.

3. Alaska

Average Death Rate per 100,000 People (2019): 23.9

Alaska, the other state that made up the top three ranking for states with the highest costs due to excessive alcohol consumption, also ranks third for alcohol-related death rates. Furthermore, Alaska also ranked 11th for alcohol consumption per capita for 2022. Their 2019 death rate for deaths caused by alcohol was 23.9 per 100,000. 

4. South Dakota

Average Death Rate per 100,000 People (2019): 21.2

South Dakota, if it wasn’t obvious, is located directly below North Dakota in the Upper Midwest region of the United States. For 2022, it ranked tenth for alcohol consumption per 100,000 of the population, so it’s unsurprising that it ranks fourth-highest for death rates relating to alcohol, at 21.2 per 100,000.

5. Montana        

Average Death Rate per 100,000 People (2019): 20.3

Montana, having previously ranked in the top five for alcohol consumption per capita for 2022, now ranks fifth for death rates relating to alcohol consumption. As of 2019, the state has recorded a death rate of 20.3 per 100,000 of the population.

All states with most alcohol related deaths

 

Important: Mixing alcohol and medicines such as Vyvanse, Trulicity and Farxiga can be harmful. Alcohol can make you sleepy, drowsy, or lightheaded. Drinking alcohol whilst taking any of the medicines mentioned above can intensify these effects and you may have trouble concentrating, and performing manual or mechanical tasks.

Methodology

We took the alcohol consumption rates from the World Population Review, which has recorded consumption in gallons per capita of each state’s population for 2022, we then simply ranked each state on that value.

Next, we used the Centers for Disease Control to get the total cost of excessive alcohol consumption per state, which was further broken down into cost per drink and per capita. We ranked each state on its per capita value, to give a more accurate representation. This site webpage was last reviewed on April 12th, 2022, at the time of writing.

Finally, we used Drug Abuse Statistics to get the overall death rates for alcohol-related deaths for each state, which were already shown as per 100,000 of the population. We then ranked each state on that value.

What happens if you take too much Ozempic?

It’s always recommended to take your medication as prescribed by your doctor. You may experience severe hypoglycemia (low blood sugar) if you take too much Ozempic. Learn more about the risks associated with taking too much Ozempic.

What is Ozempic?

Ozempic (semaglutide) is a diabetes medication manufactured by Novo Nordisk. It is approved by the US Food and Drug Administration (FDA) to:

  • Lower blood sugar in addition to diet and exercise in patients with type 2 diabetes. It has not been studied in patients with pancreatitis and it is not indicated for use in type 1 diabetes mellitus or diabetic ketoacidosis
  • To reduce the risk of major adverse cardiovascular events (heart attack and stroke) in adults with type 2 diabetes mellitus and established heart disease

Ozempic active ingredients

Ozempic is a glucagon-like peptide 1 receptor agonist (GLP-1 receptor agonist) that helps lower your blood sugar levels. The active ingredient in Ozempic is semaglutide which stimulates insulin secretion and lowers glucagon secretion, depending on your blood glucose level.

What doses of Ozempic are available?

Ozempic is available in injection form, in single-patient-use pens that deliver 0.25 mg or 0.5 mg per injection, or as single-patient-use pens that deliver 1 mg per injection.

How does Ozempic work

Ozempic is a glucagon-like peptide 1 (GLP-1) receptor agonist. Glucagon-like peptide-1 is a hormone that has multiple effects on glucose through its action on GLP-1 receptors. By binding and activating these receptors, Ozempic lowers blood glucose by stimulating insulin secretion and reducing glucagon secretion. These are both done in a glucose-dependent manner. This means when your blood glucose is high, your body will release more insulin and less glucagon. Ozempic also slightly delays the time it takes your food to empty out of your stomach immediately after eating. This can help reduce the rate at which glucose circulates in your bloodstream.

How to take Ozempic

You take Ozempic by injecting it under your skin as a subcutaneous injection, using a pre-filled pen. The medication is long-lasting so you usually take it once per week. As it’s a non-insulin medication, your doctor may prescribe Ozempic alongside insulin. Make sure you always use your Ozempic as directed by your doctor.

  • Read the Instructions for Use that come with the pen
  • Use Ozempic exactly as your healthcare provider prescribes it. Do not take more than the amount prescribed
  • Your healthcare provider should show you how to use Ozempic before you use it for the first time
  • Ozempic is injected under the skin (subcutaneous injection) of your stomach, thigh, or upper arm. Do not inject it into a muscle or vein
  • Use Ozempic at any time of the day on the same day each week. You may change the day of the week you take this medication as long as your last dose was given 2 or more days before
  • If you miss a dose of Ozempic, take the missed dose as soon as possible if it’s within 5 days of the missed dose. If more than 5 days have passed, skip the missed dose and take your next dose on the regularly scheduled day
  • You can take Ozempic with or without food
  • Don’t mix insulin and Ozempic in the same injection. You may inject them both in the same area but not right next to each other
  • Rotate injection sites with each injection
  • Continue on your diet and exercise program while on Ozempic
  • Discuss with your healthcare professional how to prevent, recognize and manage low blood sugar (hypoglycemia), and high blood sugar (hyperglycemia)
  • Do not share your Ozempic pens with other people to reduce your risk of infection
  • The medication is supplied with a Medication Guide from the manufacturer
  • Store this medication in the refrigerator (36°F to 46°F) before its first use. After its first use, you can store it at a controlled room temperature (59°F to 86°F) or refrigerated (36°F to 46°F) for 56 days. Keep the pen cap on when not in use. Ozempic should be stored away from heat, direct sunlight, and moisture

RELATED: Does Ozempic need to be refrigerated?

Always speak with your healthcare provider for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

What happens if you take too much Ozempic?

Ozempic is a long-acting treatment that can cause severe hypoglycemia (low blood sugar) if not used as prescribed. If you take more than your prescribed dose, call your healthcare provider immediately. Symptoms of low blood sugar include:

  • Headache, dizziness, confusion
  • Nausea, vomiting
  • Shaking, sweating
  • Feeling weak, tiredness
  • Hunger
  • Blurred vision
  • Seizures

To quickly treat hypoglycemia, eat or drink hard candy, crackers, raisins, fruit juice, or non-diet soda. Your doctor may prescribe a glucagon injection in case of severe hypoglycemia.

Ozempic side effects

The most common side effects of Ozempic include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Constipation
  • Weight loss

In rare instances, Ozempic can cause more serious side effects. These can include:

  • An increased risk of thyroid tumors, including cancerous tumors
  • Inflammation of your pancreas (pancreatitis)
  • Very low blood sugar (hypoglycemia)
  • Diabetic retinopathy complications
  • Gallbladder disease
  • Acute kidney disease, kidney problems, and kidney failure
  • Serious allergic reaction (shortness of breath)

Your doctor will assess the benefits of using Ozempic against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Ozempic to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ozempic drug interactions

Ozempic can interact with other medications. These include:

  • Oral anticoagulants – warfarin
  • Insulin – Ozempic can be used alongside insulin, but your doctor may change the dose of insulin you take and/or how often you take insulin
  • Any other medications taken to treat type 2 diabetes – glyburide, glimepiride, metformin, repaglinide, and sulfonylureas such as tolbutamide

This list is not exhaustive and other drugs may interact with Ozempic, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking.

Ozempic contraindications

You should not use Ozempic if you:

  • Are allergic to the active ingredient semaglutide, or any of the other ingredients in Ozempic
  • Have had, or have a family history of medullary thyroid carcinoma (medullary thyroid cancer)
  • Have an endocrine system condition called multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Have pancreatitis
  • Have type 1 diabetes (Ozempic is for type 2 diabetes only)
  • Are under 18 years of age

Talk to your doctor about your medical condition before using Ozempic if you:

  • Have had any problems with your pancreas or kidneys
  • Have ever had diabetic retinopathy
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Ozempic alternatives

The following FDA-approved alternatives to Ozempic are available:

  • Trulicity (dulaglutide) – a GLP-1 receptor agonist used to treat type 2 diabetes
  • Victoza (liraglutide) – a GLP-1 receptor agonist used to treat type 2 diabetes. It may also be used to help lower blood sugar levels in children 10 years of age and older with type 2 diabetes
  • Rybelsus (semaglutide) – used with diet and exercise to improve blood sugar (glucose) in adults with type 2 diabetes
  • Wegovy (semaglutide) – for chronic weight management and obesity

How do I know when my Ozempic pen is empty?

Ozempic is one of the newer diabetic treatments available, and the Ozempic pen is one of the easiest options to use. The biggest advantage of using the Ozempic Pen is that you only need to take it once a week. Here we will talk about Ozempic, how it works, its side effects and interactions, and how to prepare, use and check that your Pen device isn’t empty using the dose counter on the pen.

What is Ozempic?

Ozempic is an antidiabetic medication manufactured by Novo Nordisk A/S, used to improve blood sugar control. It is approved by the US Food and Drug Administration (FDA) to:

  • Lower blood sugar in addition to diet and exercise in patients with type 2 diabetes. It has not been studied in patients with pancreatitis and it is not indicated for use in type 1 diabetes mellitus or diabetic ketoacidosis
  • To reduce the risk of major adverse cardiovascular events (heart attack and stroke) in adults with type 2 diabetes mellitus and established heart disease

Ozempic is a glucagon-like peptide 1 receptor agonist (GLP-1 receptor agonist) that helps lower your blood sugar levels. The active ingredient in Ozempic is semaglutide which stimulates insulin secretion and lowers glucagon secretion, depending on your blood glucose level. Ozempic also slightly delays gastric emptying (the time it takes your food to empty out of your stomach immediately after eating). This can help reduce the rate at which glucose circulates in your bloodstream.

More information on what is Ozempic

How to use Ozempic

Ozempic is available in injection form, in single-patient-use pens that deliver 0.25 mg (starting dose) or 0.5 mg per injection, or in single-patient-use pens that deliver 1 mg per injection. Your pen is designed to be used with NovoFine Plus needles up to a length of 8 mm.

Use Ozempic by injecting it under your skin as a subcutaneous injection, using a pre-filled pen once per week. As it’s a non-insulin medication, your doctor may prescribe Ozempic alongside insulin. Make sure you always use your Ozempic as directed by your doctor.

  • Your healthcare provider will show you how to use Ozempic before you use it
  • Inject Ozempic under the skin as a subcutaneous injection into your stomach, thigh, or upper arm. Do not inject it into a muscle or vein
  • Ozempic is a weekly injection used at any time of the day, with or without food on the same day each week
  • If you miss a dose of Ozempic, take the missed dose as soon as you remember. If more than 5 days have passed, skip the missed dose and take your next dose on your regular scheduled day
  • Do not use the same injection site for each injection
  • Continue your treatment program of diet, exercise, and body weight control while on Ozempic
  • Do not share Ozempic pens with other people, even if the needle has been changed. Use a new needle each time you use Ozempic
  • Store unopened Ozempic injection pens in the refrigerator before its first use. You can store opened Ozempic at room temperature or refrigerate it for 56 days. Keep the pen cap on when not in use. Store Ozempic away from heat, direct sunlight, and moisture
  • Discard the pen 56 days after the first use, or if less than 0.25 mg is shown on the dose counter. Discard your Ozempic pen in a sharps container, according to state or local laws. Keep out of the reach of children and pets

Read the full prescribing information provided and speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

How to prepare my Ozempic Pen

  • Remove the pen cap
  • Take a new Novofine needle. Tear off the paper tab and attach the needle. A drop of solution may appear at the needle tip. This is normal, but you must still check the flow if you are using a new pen for the first time
  • Turn the dose selector to the flow check symbol () right past ‘0’. Make sure a drop appears at the needle tip before you use a new pen to make sure the solution is flowing
  • Turn the dose selector until the dose counter shows your dose. You can turn the dose selector forwards or backward to the correct dose

How do I know when my Ozempic pen is empty?

Before your first injection with each new pen, check the flow remaining in the pen. To see how much Ozempic is left in the pen, use the dose counter on the pen.

Turn the dose selector until the dose counter stops at your prescribed dosage. If the dose counter shows a number that is above your Ozempic dosage of 0.25 mg, 0.5 mg, 1 mg, or 2 mg,  this means your Pen still contains at least 0.25 mg, 0.5 mg, 1 mg or 2mg of Ozempic.

If the dose counter stops below 0.25 mg, 0.5 mg, 1 mg or 2mg, this means there is not enough Ozempic left for a full dose and you’ll need to start a new Ozempic pen.

Do not try to refill your empty pen. Once empty, the Ozempic pen must be disposed of without a needle on as instructed by your healthcare professional.

What happens if you take too much Ozempic?

Ozempic is a long-acting treatment that can cause severe hypoglycemia (low blood sugar) if not used as prescribed. You can read more about what happens if you take too much Ozempic.  If you take more than your prescribed dose, call your healthcare provider. To treat hypoglycemia quickly, eat or drink hard candy, crackers, raisins, drink fruit juice, or non-diet soda. Your doctor may prescribe you a glucagon injection in case of severe hypoglycemia.

RELATED: What happens if you take too much Ozempic?

Ozempic side effects

The most common side effects of Ozempic include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Constipation
  • Weight loss

In rare instances, Ozempic can cause more serious side effects. These can include:

  • An increased risk of thyroid tumors, including cancerous tumors
  • Inflammation of your pancreas (pancreatitis)
  • Very low blood sugar (hypoglycemia)
  • Diabetic retinopathy complications
  • Gallbladder disease
  • Acute kidney disease, kidney problems, and kidney failure
  • Serious allergic reaction (shortness of breath)

Your doctor will assess the benefits of using Ozempic against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Ozempic to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ozempic drug interactions

Ozempic can interact with other medications. These include:

  • Oral anticoagulants – warfarin
  • Insulin – Ozempic can be used alongside insulin, but your doctor may change the dose of insulin you take and/or how often you take insulin
  • Any other medications taken to treat type 2 diabetes – glyburide, glimepiride, metformin, repaglinide, and sulfonylureas such as tolbutamide

This list is not exhaustive and other drugs may interact with Ozempic, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking.

Ozempic contraindications

You should not use Ozempic if you:

  • Are allergic to the active ingredient semaglutide, or any of the other ingredients in Ozempic
  • Have other risk factors such as a family history of medullary thyroid carcinoma (medullary thyroid cancer)
  • Have an endocrine system condition called multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Have pancreatitis
  • Have type 1 diabetes (Ozempic is for type 2 diabetes only)
  • Are under 18 years of age

Talk to your doctor about your medical condition before using Ozempic if you:

  • Have had any problems with your pancreas or kidneys
  • Have ever had diabetic retinopathy
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Lupron Depot side effects and how to avoid them

Lupron Depot is an FDA (Food and Drug Administration) approved manufactured by AbbVie Inc. It is classed as a long-acting GnRH agonist (gonadotropin-releasing hormone) and is used to treat advanced prostate cancer in men, early puberty in children, and endometriosis and uterine fibroids in women. While Lupron Depot is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Lupron Depot include hot flashes, sweats, and headaches. Less common, but more serious side effects, can include depression, mood changes, and suicidal thoughts.

Learn more about the side effects of Lupron Depot and what you can do to avoid them.

What is Lupron Depot (leuprolide acetate)?

Lupron Depot contains leuprolide as the active ingredient. It works by reducing the amount of certain hormones in the body, testosterone in men and estrogen in women.

Most types of prostate cancer need testosterone to grow and spread. Leuprolide reduces the amount of testosterone your body makes. This helps to slow or stop the growth of cancer cells and relieve painful, or difficult urination.

Leuprolide is also used to stop early puberty (precocious puberty) in children. It delays the development of the breasts and testicles, and the start of menstrual periods. It also helps to increase the likelihood of reaching normal adult height by slowing down early bone growth. Leuprolide decreases the amount of sex hormones made by a child’s body (estrogen in girls, testosterone in boys).

Lupron Depot is also used for the treatment of endometriosis (endometrial lining normally found inside the uterus begins to grow on the ovaries, fallopian tubes, or other areas near the uterus). It may be used on its own or in combination with other medicines. Using norethindrone acetate with Lupron Depot reduces certain side effects linked with Lupron Depot, such as the loss of bone mineral density as well as night sweats and hot flashes.

Lupron Depot may also be used for the treatment of uterine fibroids, in combination with iron prior to operating to reduce anemia caused by fibroids.

Lupron Depot dosage

Lupron Depot is available as depot suspension for injection, 11.25 mg lyophilized powder for reconstitution in a dual-chamber syringe.

Your dose of Lupron Depot will be based on the medical condition you are being treated for. For endometriosis, Lupron Depot is injected under the skin or into a muscle, once every month or once every 3 to 6 months. It is important to note that different brands and strengths of leuprolide are used for the treatment of different conditions. You must receive the correct brand and strength prescribed by your doctor for your condition.

If your symptoms recur after the initial course of treatment, retreatment for no more than 6 months may be considered but only in combination with norethindrone acetate. Your bone density must be assessed before retreatment begins.

You are advised to read the full prescribing information provided with this medicine for drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Lupron Depot side effects

The most common side effects of Lupron Depot include:

  • Hot flashes, sweats, headache
  • Decreased sex drive, depression, emotional lability
  • Dizziness, nausea, vomiting
  • Weight gain
  • Bone/joint pain, ankylosing spondylosis, arthritis, bone fracture
  • Muscle pain, leg cramps, muscle stiffness, muscle weakness and tenderness
  • Problems with your pituitary glands
  • Skin reaction at the injection site
  • Decreased testicle size
  • Vaginal discharge, dryness, or itching
  • Vaginal bleeding
  • Stomach pain, constipation
  • Tightness in the chest, difficulty breathing, shortness of breath
  • Mood changes
  • Headaches, feeling tired, fever, stuffy nose, sore throat, mucus cough

Lupron Depot can cause more serious side effects, including:

  • New or worsening bone pain, easily broken bones in adults
  • Increased thirst and/or urination in adults
  • Mood changes – depression, suicidal thoughts, mood swings, aggressive behavior
  • Sudden severe headache
  • Problems with your eyes or vision
  • Bone pain, loss of movement in any part of your body
  • Swelling, rapid weight gain
  • Seizures
  • Sudden chest pain, wheezing, dry cough
  • Painful or difficult urination, urinary tract infection
  • Pain in your back, numb, weak, or tingly feeling in your legs or feet
  • Muscle weakness or loss of use
  • Lack of bowel or bladder control
  • Chest pain or pressure spreading to your jaw or shoulder
  • Sudden numbness or weakness, down one side of the body, slurred speech, difficulty understanding or communicating

If you experience any of these serious side effects, stop taking Lupron Depot and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Lupron Depot drug interactions

Lupron Depot can interact with other medications including:

  • Treatments for an irregular heartbeat – amiodarone, dronedarone, bepridil, quinidine
  • Anti-depressants – citalopram, escitalopram
  • Anti-psychotics used for schizophrenia – clozapine, haloperidol, thioridazine
  • Treatment for multiple sclerosis – fingolimod, ozanimod, singolimod
  • Medication for heart failure – ivabradine
  • Treatment for cancer – nilotinib, vandetanib
  • Treatment for HIV/AIDS – saquinavir
  • Beta-blockers for high blood pressure – sotalol

Before taking Lupron Depot, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Lupron Depot warnings & precautions

Don’t take Lupron Depot if:

  • Are allergic to the active ingredient leuprolide
  • Are allergic to any of the other ingredients in Lupron Depot
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before taking Lupron Depot if you:

  • Are taking any of the medications that could interact with Lupron Depot
  • Have depression
  • Have a mental health illness or psychosis
  • Suffer from seizures or have epilepsy
  • Have heart disease, congestive heart failure, long QT syndrome, blood vessel disorder, or a family history of these conditions
  • Have a brain tumor or have had a spinal cord injury
  • Have high or low levels of potassium or magnesium
  • Have osteoporosis
  • Are taking steroids long term
  • Smoke or drink alcohol

You should always check with your doctor or pharmacist before taking any medication, including Lupron Depot, to make sure it is safe for you.

Other warnings you should know about

  • This drug stops you from having a period (menstrual bleeding), but is not a method of birth control. Use a non-hormone type of birth control like condoms to prevent pregnancy while taking this drug
  • Lupron carries a warning of an increased risk of heart attacks, strokes, and sudden death in men
  • Get medical help right away if you notice any symptoms of a serious allergic reaction, including skin rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing

How to avoid Lupron Depot side effects

The best way to avoid side effects is to take Lupron Depot as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Lupron Depot that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Lupron Depot. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Know the signs and symptoms of Lupron Depot side effects

Signs and symptoms of side effects include hot flashes, night sweats and weight gain. If you experience any of these symptoms speak to your doctor for medical advice.

5. Monitor your weight

Lupron Depot may cause weight gain. If you experience this side effect while taking Lupron Depot, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Lupron Depot.

10. Get regular medical check ups

If you have side effects it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Lupron Depot as needed.

Viibryd side effects and how to avoid them

Viibryd is a brand-name medication manufactured by Trovis Pharmaceuticals. It is classed as an antidepressant and is used for the treatment of major depressive disorder (MDD). While Viibryd is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Viibryd include nausea, dizziness, and insomnia. Less common, but more serious side effects, can include a reduced sex drive.

Learn more about the side effects of Viibryd and what you can do to avoid them.

What is Viibryd (vilazodone)?

MDD, or depression, is a mental health disorder. It has a range of symptoms, but normally you’re diagnosed with MDD if you have major depressive episodes. These are periods that last at least two weeks where you feel depressed most of the time and your daily life is disrupted. MDD can cause feelings of depression, worthlessness, and guilt. You may experience low energy levels, a lack of interest in activities you previously enjoyed, poor attention, and suicidal thoughts.

Viibryd contains vilazodone an SSRI (selective serotonin reuptake inhibitor) and partial serotonin receptor agonist as the active ingredient. Viibryd works by increasing the amount of serotonin in your brain. Serotonin is released by nerve cells in your brain. Once released, it interacts with other cells in your brain, influencing your mood, your thoughts, and your emotions. When serotonin is released, it’s either used quickly or reabsorbed into the nerve cell that released it. Vilazodone increases your levels of serotonin by stopping it from being reabsorbed.

Always check with your doctor or pharmacist before taking any medication, including Viibryd, to make sure it is safe for you.

Viibryd dosage

Viibryd is available in the dosages 10 mg, 20 mg, and 40 mg tablets. Viibryd should be started with an initial dose of 10 mg once daily for 7 days, followed by 20 mg once daily for 7 days, and then increased to 40 mg once daily.

You should take Viibryd with food. Taking Viibryd without food can result in inadequate drug concentrations and may reduce its effectiveness. You must reduce the dose gradually when discontinuing treatment. If you miss a dose, take it as soon as you remember, however, skip the missed dose if it is almost time for your next dose. Take your next dose at the usual time.

You are advised to read the full prescribing information and medication guide provided with this medicine for drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Viibryd side effects

The most common possible side effects of Viibryd in clinical studies include:

  • Diarrhea
  • Nausea, vomiting
  • Dry mouth, dizziness
  • Abnormal dreams and trouble sleeping

Viibryd can cause more serious side effects, including:

  • Worsening of depressive episodes and an increase in suicidal thoughts
  • Abnormal orgasm, erectile dysfunction, decreased libido, and ejaculation disorder
  • Hyponatremia (abnormally low sodium levels)
  • Bloody, black, or tarry stools, vomit that looks like coffee grounds
  • Easy bruising and/or bleeding
  • Seizures
  • Eye pain, blurred vision, seeing halos around lights

If you experience any of these serious side effects, stop taking Viibryd and seek medical attention immediately. You are encouraged to report adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Viibryd drug interactions

Viibryd can interact with other medications including:

  • Monoamine oxidase inhibitors (MAOIs) – isocarboxazid, linezolid, methylene blue, phenelzine, selegiline, or tranylcypromine. Do not take vilazodone during the 2 weeks after you stop an MAOI and wait 2 weeks after stopping vilazodone before you start taking an MAOI. You may develop confusion, agitation, stomach or intestinal symptoms, a sudden high body temperature, extremely high blood pressure, or severe seizures
  • NSAIDs (nonsteroidal anti-inflammatory drugs – ibuprofen, naproxen
  • Blood thinners – warfarin, aspirin (increased risk of bleeding)
  • Other drugs that increase serotonin – St. John’s wort, other SSRIs (paroxetine), SNRIs (duloxetine), tryptophan, buspirone, triptans, and amphetamines. The risk of serotonin syndrome, a potentially life-threatening problem, may be more likely when you start or increase the dose of these drugs
  • Lithium
  • Antifungals – fluconazole, ketoconazole, and itraconazole
  • Treatments for pain – tramadol

Before taking Viibryd, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Viibryd warnings & precautions

Don’t take Viibryd if:

  • You have had an allergic reaction to Viibryd or any of its ingredients

Talk to your doctor before taking Viibryd if you:

  • Have a liver or kidney condition
  • Have a personal or family history of angle-closure glaucoma
  • Have a history of bipolar disorder, mania, or hypomania, or you or a close family member has had these mental health problems in the past
  • Have low salt levels (sodium)
  • Are taking a diuretic
  • Are older than 65 years of age
  • Are pregnant or breastfeeding

You should always check with your doctor or pharmacist before taking any medication, including Viibryd, to make sure it is safe for you.

Other warnings you should know about

  • Viibryd can cause withdrawal symptoms upon sudden discontinuation. Symptoms can include headaches, nausea, vomiting, tiredness, feeling dizzy, and irritability
  • Viibryd may cause adolescents and young adults to become agitated, irritable, to have suicidal thoughts, or to become more depressed

How to avoid Viibryd side effects

The best way to avoid side effects is to take Viibryd as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Viibryd that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse. Selective serotonin reuptake inhibitors (SSRIs) can make you sweat more and contribute to dehydration.

3. Avoid alcohol

Avoid drinking alcohol while taking Viibryd as it can increase your risk of side effects.

4. Don’t skip meals

Viibryd should be taken with food. If taken without food the drug’s effectiveness may be diminished due to inadequate drug concentrations.

5. Know the signs and symptoms of Viibryd side effects

Signs and symptoms of side effects include insomnia, nausea, and dizziness, If you experience any of these symptoms speak to your doctor.

6. Monitor your weight

Viibryd may cause weight gain due to an increased appetite. If you experience this side effect while taking Viibryd, get medical advice from your doctor.

7. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Viibryd.

8. Get regular medical check ups

If you have side effects it is important to get regular medical check ups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Viibryd as needed.

Keytruda side effects and how to avoid them

Keytruda is a brand-name medication that is manufactured by Merck. It is classed as a type of immunotherapy treatment option for multiple types of cancer. Keytruda is a type of cancer treatment that uses the body’s own immune system to better find and attack cancer cells. While Keytruda is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Keytruda include tiredness, constipation, and decreased appetite. Less common, but more serious side effects, can include liver and kidney problems and infusion reactions.

Learn more about the side effects of Keytruda and what you can do to avoid them.

What is Keytruda (pembrolizumab)?

Keytruda is a medicine used to treat different types of cancers. You may be prescribed Keytruda if you have:

  • Skin cancer called melanoma or Merkel cell carcinoma (MCC)
  • Non-small cell lung cancer (NSCLC), or small cell lung cancer (SCLC)
  • Head and neck squamous cell cancer (HNSCC)
  • Classical Hodgkin lymphoma (cHL)
  • Mediastinal B-cell lymphoma (PMBCL)
  • Urinary tract and bladder cancer called urothelial carcinoma
  • Microsatellite instability-high (MSI-H) or a mismatch repair deficient (dMMR) solid tumor
  • Gastric or gastroesophageal junction (GEJ) adenocarcinoma
  • Squamous cell carcinoma of the esophagus
  • Cervical cancer
  • Triple-negative breast cancer (TNBC)
  • Hepatocellular carcinoma
  • Renal cell carcinoma (RCC)
  • Endometrial carcinoma

Keytruda is often used when your cancer has spread (metastatic), if it can not be removed by surgery, it hasn’t responded to chemotherapy, or if your cancer tumors have certain abnormal genes. Keytruda can be used alone, or it can be used alongside other treatments like chemotherapy or radiotherapy. Rather than being a type of chemotherapy or radiotherapy, Keytruda is an immunotherapy that works with your immune system to help you fight your cancer. It is given through a drip into one of your veins (intravenous), usually under the supervision of a doctor or nurse. Keytruda can be used alone, or it can be used alongside other treatments like chemotherapy or radiotherapy.

The active ingredient in Keytruda is called pembrolizumab. It works by helping your immune system to fight cancerous tumors. Some cancerous tumors protect themselves from your immune system by producing a protein called programmed cell death protein 1 (PD-1). This protein forms on the outside of the tumor turning your immune system’s T cells off. This stops your immune system from attacking and destroying the tumor. But pembrolizumab removes this protection. Keytruda attaches itself to the PD-1 proteins stopping them from working. This allows your immune system to fight the cancerous tumor.

Keytruda dosage

Keytruda is available as 50 mg lyophilized powder for injection in single-dose vials for reconstitution and as 100 mg/4 mL (25 mg/mL) solution in single-dose vials.

Your dose of Keytruda will be based on the condition you are being treated for but is typically 200 mg every 3 weeks. Your doctor may increase your dose if needed.

You are advised to read the full prescribing information provided with this medicine for drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Keytruda side effects

The most common possible side effects of Keytruda in clinical trials compared to placebo include:

  • When used alone – tiredness, pain, including pain in muscles, skin rash, diarrhea, fever, cough, decreased appetite, shortness of breath, trouble breathing, constipation, bones or joints pain, abdominal pain, nausea, and low levels of thyroid hormone
  • Common side effects of Keytuda, when given with other medication – tingling or numbness of the arms or legs, hair loss, low red blood cell count (anemia), tiredness, nausea, low white blood cells, diarrhea, high blood pressure, decreased platelets, constipation, joint pain, vomiting, urinary tract infection, skin rash, low thyroid hormone levels (hypothyroidism) and decreased appetite

Keytruda can cause more serious side effects, including:

  • Severe infusion reactions
  • Rejection of a transplanted organ
  • Skin reactions – rash, itching, skin blistering or peeling, painful sores or ulcers in your mouth, nose, throat, or genital area
  • Fever or flu-like symptoms
  • Lung problems (pneumonitis) – chest pain, shortness of breath, a new or worse cough
  • Intestinal problems (colitis) – diarrhea or more bowel movements than usual, stomach tenderness and pain, stools that are black, sticky, or have blood or mucus in them
  • Liver problems (hepatitis) – pain on the right side of your stomach, yellowing of your skin or the whites of your eyes, dark urine, bruising or bleeding more easily than normal
  • Kidney problems – changes in the amount or color of your urine
  • Hormone gland problems (particularly the thyroid, pituitary, adrenal glands, and pancreas) – weight loss or weight gain, feeling more hungry or thirsty, increased sweating, a rapid heartbeat, feeling cold, hair loss, feeling very weak, dizziness or fainting, headaches that will not go away
  • Changes in vision
  • Severe muscle weakness, persistent muscle or joint pains

If you experience serious side effects, stop taking Keytruda and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Keytruda drug interactions

Keytruda can interact with other medications including:

  • Corticosteroids – betamethasone, dexamethasone, prednisolone
  • Immunomodulatory drugs – lenalidomide, thalidomide

Before taking Keytruda, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Keytruda warnings & precautions

Don’t take Keytruda if:

  • Are allergic to the active ingredient pembrolizumab
  • Are allergic to any of the other ingredients in Keytruda (these will be listed in the leaflet which comes with the medication)

Talk to your doctor before taking Keytruda if you:

  • Are taking any of the medications that could affect your immune system and interact with Keytruda
  • Have an autoimmune disease, like Crohn’s disease, ulcerative colitis, or lupus
  • Have pneumonia or inflammation of your lungs (pneumonitis)
  • Were previously given a medication called ipilimumab and you experienced serious side effects
  • Have had an allergic reaction to other monoclonal antibody therapies
  • Have had any liver problems or liver damage
  • Have had any kidney problems or have kidney damage
  • Have HIV or AIDS
  • Have had an organ transplant
  • Have had a bone marrow transplant that used donor stem cells
  • Have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Keytruda, to make sure it is safe for you.

Other warnings you should know about

Infusion reactions can sometimes be severe or life-threatening. Signs and symptoms may include chills or shaking, itching or rash, flushing, shortness of breath, dizziness, feeling lightheaded, fever, and back pain

How to avoid Keytruda side effects

The best way to avoid side effects is to take Keytruda as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Keytruda that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Keytruda. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Alcohol can cause side effects similar to some of Keytruda’s. These include diarrhea, tiredness, and nausea. Alcohol may make these side effects worse during Keytruda treatment.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Know the signs and symptoms of side effects

Signs and symptoms of side effects include diarrhea, constipation, and abdominal pain. If you experience any of these symptoms speak to your doctor for medical advice.

7. Monitor your weight

Keytruda may cause weight loss. If you experience this while taking Keytruda, get medical advice from your doctor.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Keytruda.

9. Get regular medical checkups

If you have side effects it is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Keytruda as needed.

Aimovig side effects and how to avoid them

Aimovig is a brand-name medication manufactured by Amgen, used for migraine prevention. While Aimovig is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Aimovig include injection site reactions and muscle cramps. Less common, but more serious side effects, can include allergic reactions and hypertension.

Learn more about the side effects of Aimovig and what you can do to avoid them.

What is Aimovig (erenumab)?

Aimovig is a prescription medicine given to adults for the treatment of migraine headaches. It contains the active ingredient erenumab-aooe, a monoclonal antibody.

Erenumab works by blocking the action of a molecule called calcitonin gene-related peptide (CGRP). CGRP normally attaches to receptors on cells in your brain thought to be involved in triggering migraine attacks. Erenumab attaches to these receptors instead of CGRP, stopping it from stimulating the receptors and preventing migraines.

Aimovig dosage

Aimovig is available in injection form as 70 mg/mL solution in a single-dose prefilled autoinjector, and 70 mg/mL solution in a single-dose prefilled syringe.

Aimovig is for subcutaneous use only. Inject into the abdomen, thigh, or upper arm. The recommended dose is 70 mg once monthly. Some patients may require a dosage of 140 mg once monthly.

Take this medication out of the refrigerator before use. Allow the Aimovig autoinjector or syringe to warm up to room temperature for at least 30 minutes. Do not heat this medication any other way. Do not expose to direct sunlight and do not shake this medication.

You are advised to read the full prescribing information provided with this medicine for drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Aimovig side effects

The most common possible side effects of Aimovig in clinical studies compared to placebo include:

  • Injection site reactions, such as swelling, redness, and pain
  • Constipation
  • Cramps with muscle spasms

Aimovig can cause more serious side effects, including:

  • Severe allergic reactions to the medication such as swelling of the face, mouth, tongue, or throat, and problems breathing
  • Severe constipation can cause serious complications requiring hospital treatment or surgery
  • High blood pressure (hypertension) or worsening existing high blood pressure
  • Hair loss (alopecia)

If you experience any of these serious adverse reactions, stop taking Aimovig and seek medical attention immediately. You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Aimovig drug interactions

Your doctor or pharmacist can tell you more about possible interactions that may occur with the use of Aimovig. Before taking Aimovig, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Aimovig warnings & precautions

Don’t take Aimovig if:

  • Are allergic to the active ingredient erenumab-aooe
  • You have known hypersensitivity to any of the other ingredients in Aimovig
  • Are under 18 years of age

Talk to your doctor before taking Aimovig if you:

  • Are allergic to rubber or latex, as the caps of the prefilled SureClick and prefilled syringes contain a natural rubber similar to latex
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Aimovig, to make sure it is safe for you.

Other warnings you should know about

Serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening to this drug are rare. Get medical help right away if you notice any symptoms of a serious allergic reaction, including hives, rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing

How to avoid Aimovig side effects

The best way to avoid side effects is to take Aimovig as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Aimovig that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Avoid alcohol

Avoiding alcohol while taking Aimovig is not required, however, drinking alcohol can trigger or worsen a migraine headache in many people.

3. Know the signs and symptoms of Aimovig side effects

Signs and symptoms of side effects include muscle spasms and injection site reactions. If you experience any of these symptoms speak to your doctor.

4. Monitor your weight

Weight gain and weight loss are not side effects reported in studies of Aimovig.

5. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Aimovig.

6. Get regular medical checkups

If you have migraine attacks it is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Aimovig as needed.

Pristiq side effects and how to avoid them

Pristiq is a brand-name medication manufactured by Wyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc. It is classed as a serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder. While Pristiq is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Pristiq include nausea, dizziness, and trouble sleeping. Less common, but more serious side effects, can include allergic reactions and hypertension.

Learn more about the side effects of Pristiq and what you can do to avoid them.

What is Pristiq (desvenlafaxine)?

Pristiq is an antidepressant medication prescribed to adults to treat major depressive disorder, often just called depression, a common but serious mood disorder.

The active ingredient in Pristiq is called desvenlafaxine, a type of antidepressant called a serotonin and norepinephrine reuptake inhibitor (SNRI). When you swallow a Pristiq tablet, it dissolves in your digestive system and releases desvenlafaxine into your bloodstream. Desvenlafaxine is then carried in your blood to your brain, where it slows how quickly you break down two substances called serotonin and norepinephrine.

Serotonin and norepinephrine are natural substances produced in your brain. They’re called neurotransmitters. They help regulate your brain function by controlling how the nerve cells in your brain communicate with each other. By slowing how quickly serotonin and norepinephrine are broken down, desvenlafaxine causes their levels to increase.

Serotonin and norepinephrine regulate brain function in terms of thinking, emotion, mood, learning, reward, alertness, and many more. Research has shown that increasing levels of serotonin and norepinephrine can help reduce the symptoms of depression.

Pristiq is not approved to treat bipolar depression. Talk to your doctor about your mental health before taking any medication to make sure it is safe for you.

Pristiq dosage

Pristiq is available as extended-release tablets, each containing 76 mg or 152 mg of desvenlafaxine succinate equivalent to 50 mg or 100 mg of desvenlafaxine.

The recommended dose of Pristiq is 50 mg once daily with or without food. Gradual dose reduction is recommended whenever possible when stopping treatment. Tablets should be taken whole, do not break, crush, chew, or dissolve the tablets. Your recommended dose will need to be adjusted if you have moderate or severe renal impairment or hepatic impairment.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Pristiq side effects

The most common possible side effects of Pristiq compared to placebo include:

  • Nausea
  • Dry mouth
  • Constipation
  • Dizziness
  • Sweating
  • Trouble sleeping
  • Drowsiness
  • Blurred vision, eye pain, eye swelling, or seeing halos around lights
  • Anxiety
  • Decreased appetite
  • Sexual dysfunction, like difficulties getting or keeping an erection, and problems with ejaculation

Pristiq can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • An increased risk of suicidal thoughts and suicide, particularly in young adults
  • Risk of serotonin syndrome – a potentially life-threatening condition caused by high levels of serotonin
  • Hyponatremia – low levels of sodium in your blood that can cause serious health problems and death
  • New or worsening hypertension (high blood pressure)
  • Lung problems that can cause discomfort and coughs, and cause trouble breathing
  • Seizures
  • An increased risk of developing an eye condition called angle-closure glaucoma
  • An increased risk of bleeding if taken with medications that can reduce blood clotting, like blood thinners, aspirin, or NSAIDs like ibuprofen

If you experience any of these serious side effects, stop taking Pristiq and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Pristiq drug interactions

Pristiq can interact with other medications including:

  • Any other antidepressants, like tricyclic antidepressants, SSRIs, other SNRIs (serotonin-norepinephrine reuptake inhibitors), or lithium
  • Any other medications containing desvenlafaxine or venlafaxine
  • Any other medications that can affect your serotonin or norepinephrine levels
  • Any other medications taken to treat mental states and conditions, like mood and thought disorders, anxiety, or psychotic disorders
  • Any medications that can reduce blood clotting, like warfarin, aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Medications called triptans, used for migraines
  • Medications containing amphetamines often used to treat attention deficit hyperactivity disorder (ADHD)
  • Tryptophan
  • Opioid pain medications, like fentanyl or tramadol
  • An herbal supplement called St. John’s Wort

Before taking Pristiq, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Pristiq warnings & precautions

Don’t take Pristiq if:

  • Are allergic to the active ingredient desvenlafaxine, or to venlafaxine
  • Are allergic to any of the other ingredients in Pristiq
  • Are taking an antibiotic called linezolid
  • Are being treated with an intravenous medication called methylene blue
  • Are under 18 years of age

Talk to your doctor before taking Pristiq if you:

  • Are taking any of the medications that could interact with Pristiq
  • Have, or have had, depression, suicidal thoughts, or have ever tried to commit suicide
  • Have, or have any family history, of mania, hypomania, or bipolar disorder
  • Have any heart problems
  • Have previously had a stroke
  • Have any kidney problems
  • Have any liver problems
  • Have hypertension (high blood pressure)
  • Have high cholesterol or high triglycerides (blood fats)
  • Have low blood sodium levels
  • Have, or have had, any bleeding problems
  • Have ever had a seizure
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – This drug passes into breast milk and may cause unwanted effects on a nursing infant. Consult your doctor before breast-feeding

You should always check with your doctor or pharmacist before taking any medication, including Pristiq, to make sure it is safe for you.

Other warnings you should know about

  • Increased risk of suicidal thoughts and behavior in children, adolescents, and young adults taking antidepressants for major depressive disorder (MDD) and other psychiatric disorders. See the full prescribing information for the complete boxed warning
  • Avoid taking monoamine oxidase inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. MAOIs should not be taken for two weeks before and at least 7 days after treatment with Pristiq
  • Pristiq can cause low blood sodium levels. Your risk of this side effect is increased if you are 65 years of age or older or take a diuretic. Taking Pristiq could worsen your condition if you already have low sodium levels
  • Antidepressant discontinuation syndrome can occur when stopping treatment with antidepressants, such as Pristiq. Withdrawal symptoms can include aggressive or hostile behavior, confusion, trouble sleeping, seizures, and suicidal thoughts

How to avoid Pristiq side effects

The best way to avoid side effects is to take Pristiq as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Pristiq that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Avoid alcohol

Avoid drinking alcohol while taking Pristiq as it can increase your risk of side effects.

3. Know the signs and symptoms of Pristiq side effects

Signs and symptoms of side effects include insomnia, drowsiness, and sexual dysfunction. If you experience any of these symptoms speak to your doctor for medical advice.

4. Monitor your weight

Pristiq may cause weight gain. If you experience this side effect while taking Pristiq, get medical advice from your doctor.

5. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Pristiq.

6. Get regular medical checkups

If you have side effects it is important to get regular medical checkups. Your doctor will monitor your medical condition and may adjust your dose of Pristiq as needed.

Farxiga side effects and how to avoid them

Farxiga is a brand-name medication manufactured by AstraZeneca. It is classed as a sodium-glucose co-transporter 2 (SGLT-2 inhibitor) and is used to treat Type 2 diabetes, heart failure, and chronic kidney disease (CKD).

While Farxiga is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Farxiga include constipation, back pain, and weight loss. Less common, but more serious side effects, can include urinary tract infections, diabetic ketoacidosis, and low blood sugar.

Learn more about the Farxiga side effects and what you can do to avoid them.

What is Farxiga (dapagliflozin)?

Farxiga is used to reduce high blood sugar levels in people who have type 2 diabetes. It is also used in certain people to lower the risk of hospitalization for heart failure. In people with type 2 diabetes, it’s approved to:

  • Improve blood sugar levels when used in combination with changes to diet and exercise
  • Reduce the risk of hospitalization for heart failure in people with heart disease or risk factors for heart disease

In people with heart failure with or without type 2 diabetes, Farxiga is approved to reduce the risk of hospitalization for heart failure or cardiovascular death in people with reduced ejection fraction. For those with chronic kidney disease that may worsen, Farxiga is approved to reduce the risk of:

  • Lowered glomerular filtration rate (GFR)
  • End-stage kidney disease
  • Cardiovascular death
  • Hospitalization for heart failure

The active ingredient in Farxiga is called dapagliflozin. When absorbed into your bloodstream, dapagliflozin slows down the rate at which your kidneys absorb glucose from your blood. This causes your kidneys to release sugar into your urine. Your blood sugar levels then fall as you urinate. Farxiga can be used in combination with some other diabetes medications, including insulin, metformin, or sulfonylurea.

Farxiga is not approved to treat type 1 diabetes and should not be used to treat diabetic ketoacidosis (DKA).

Farxiga dosage

Farxiga is available as 5 mg and 10 mg tablets. For Type 2 diabetes mellitus the recommended starting dose is 5 mg once daily, taken in the morning. The dose may be increased to 10 mg once daily if 5 mg is tolerated but require additional glycemic control.

To reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and cardiovascular disease or multiple cardiovascular risk factors, the recommended dose is 10 mg once daily. For heart failure, the recommended dose is 10 mg once daily.

If you miss a dose, take it as soon as you remember. If it is almost the time of your next dose, skip the missed dose and take your next dose at the normal time.

You are advised to read the medication guide provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How effective is Farxiga?

Farxiga reduces the risk of hospitalization due to heart failure or cardiovascular death by 26% when used with standard-of-care treatment in people with heart failure with reduced ejection fraction.

What are the side effects of Farxiga?

The most common possible side effects of Farxiga include:

  • Dehydration, changes in urination, dizziness, back pain
  • Constipation
  • Weight loss

Farxiga can cause more serious side effects, including:

  • Low blood sugar (hypoglycemia)
  • More serious urinary tract infections (UTI)
  • Inflammation of the pancreas
  • Diabetic ketoacidosis
  • A rare bacterial infection that damages the tissue under the skin in the area between the anus and genitals (necrotizing fasciitis)
  • Unusual tiredness, nausea, vomiting, abdominal pain, trouble breathing
  • Ketoacidosis (increased ketones in your blood or urine)
  • Increase in your cholesterol levels

If you experience any of these serious side effects, stop taking Farxiga and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Farxiga drug interactions

Farxiga can interact with other medications including:

  • Beta-blockers – atenolol, bisoprolol, sotalol
  • Diuretics – bendroflumethiazide, bumetanide, furosemide
  • Antipsychotics – clozapine
  • Corticosteroids – cortisone, dexamethasone, hydrocortisone
  • ACE inhibitors – captopril, enalapril, ramipril

Farxiga can interact with other medications, changing how it and other medications work. If this happens, side effects may be more likely. Tell your prescribing physician about all drugs you’re taking, including vitamins and dietary supplements. In particular, let them know if you’re taking a diuretic or any other medications for diabetes like insulin or sulfonylureas.

Farxiga warnings & precautions

Don’t take Farxiga if:

  • Are allergic to the active ingredient dapagliflozin
  • Are allergic to any of the other ingredients found in Farxiga (listed in the leaflet which comes with the medication)
  • Have diabetic ketoacidosis or a history of diabetic ketoacidosis
  • Have severe kidney issues or are on dialysis
  • Are pregnant or breastfeeding – It is unknown if this drug passes into breast milk
  • Are under 18 years of age

Talk to your doctor before taking Farxiga if you:

  • Have Type 1 diabetes
  • Have liver or kidney problems
  • Have heart disease
  • Are over 65 years of age
  • Are taking medication to lower your blood pressure or have a history of low blood pressure
  • Often get urinary tract infections

You should always check with your doctor or pharmacist before taking any medication, including Farxiga, to make sure it is safe for you.

Other warnings you should know about

  • Farxiga can cause a rare but very serious bacterial infection in the genital/anal area (Fournier’s gangrene) in people with type 2 diabetes. Call your doctor right away if you have signs of a yeast infection in the vagina (unusual discharge, burning, itching, or smell) or in the penis (redness, itching, swelling, or unusual discharge from the penis)
  • Farxiga can increase your risk of kidney damage. This is more likely to occur if you are dehydrated, have kidney or heart problems if you take medications that affect your kidneys, or are over 65 years of age. Your doctor may test your kidney function during treatment with Farxiga
  • Farxiga may cause serious allergic reactions such as skin rash, hives, swelling of your face, lips, tongue, and throat, and difficulty breathing or swallowing. Contact your healthcare provider or go to the nearest hospital emergency room right away if you have these side effects

How to avoid Farxiga side effects

The best way to avoid side effects is to take Farxiga as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Farxiga that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Farxiga. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse. Tell your doctor right away if you have any signs of dehydration, such as urinating less than usual, unusual dry mouth, thirst, fast heartbeat, or feeling lightheaded or faint especially when you stand up (orthostatic hypotension).

4. Avoid alcohol

Avoid drinking or limit your alcohol intake while taking Farxiga as alcohol may raise your blood sugar and cause dehydration. If you have diabetes, this can cause your condition to worsen. In addition, Farxiga can cause a condition called diabetic ketoacidosis as well as dehydration.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Farxiga.

7. Know the signs and symptoms of Farxiga side effects

Signs and symptoms of side effects of Farxiga include dehydration, dizziness, and weight loss. If you experience any of these symptoms speak to your doctor for medical advice.

8. Monitor your weight

Farxiga may cause weight loss. If you experience this side effect while taking Farxiga, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Farxiga.

10. Get regular medical checkups

If you have side effects it is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your condition and may adjust your dose of Farxiga as needed.

Myrbetriq side effects and how to avoid them

Myrbetriq is a brand-name medication manufactured by Astellas Pharma US, Inc. It is used to treat an overactive bladder (OAB) in adults. While Myrbetriq is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Myrbetriq include urinary tract infections, nausea, and headaches. Less common, but more serious side effects, can include irregular heartbeats, and palpitations.

Learn more about the side effects of Myrbetriq and what you can do to avoid them.

What is Myrbetriq (mirabegron)?

Myrbetriq contains mirabegron, a beta-3 adrenergic agonist as the active ingredient. It is used to treat an overactive bladder in adults. An overactive bladder is a condition where you feel the need to urinate often and sometimes suddenly. You may feel a combination of needing to urinate often (increased urinary frequency), needing to urinate suddenly (urinary urgency), or losing control of when you want to urinate (urinary incontinence). It is also used to treat neurogenic detrusor overactivity (NDO).

Mirabegron relaxes the muscles in the wall of your bladder (detrusor urinae muscle) helping to reduce the symptoms of an overactive bladder. It does this by attaching itself to areas on the surface of the muscles called β3-adrenergic receptors. These receptors are stimulated by mirabegron, starting a process that relaxes the bladder muscles.

Myrbetriq dosage

Myrbetriq is available as 25 mg and 50 mg extended-release tablets.

The recommended starting dose of Myrbetriq is 25 mg once daily, alone or in combination with solifenacin succinate (Vesicare) 5 mg, once daily. Your dose of Myrbetriq may be increased to 50 mg once daily, based on its effectiveness and your ability to tolerate it.

Swallow the tablets whole with water, with or without food, do not chew, divide or crush. If you miss a dose, take the missed dose as soon as possible. If however, it’s been 12 hours or more since your dose was supposed to be taken, skip it and take the next dose at the normal time. Store Myrbetriq at room temperature, away from heat, moisture, and direct light.

Please read the prescribing information provided with this medicine for the drug information and patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

How effective is Myrbetriq?

Myrbetriq is FDA (Food and Drug Administration)-approved for the treatment of an overactive bladder. Approval is based on clinical studies, where Myrbetriq effectively treated symptoms of overactive bladder within four to eight weeks, depending on the dosage.

Myrbetriq side effects

The most common possible side effects of Myrbetriq include:

  • Hypertension
  • Nasopharyngitis
  • Urinary tract infection (UTI)
  • Headache, dizziness, nausea
  • Fast heartbeat (tachycardia)
  • Constipation, diarrhea
  • Back pain
  • Dry mouth

Myrbetriq can cause more serious side effects, including:

  • Irregular heartbeat (atrial fibrillation) palpitations, affecting around 1 in 100 people
  • Severe rise in blood pressure (hypertensive crisis), affecting around 1 in 1,000 people

If you experience any of these serious side effects, stop taking Myrbetriq and seek medical attention immediately. You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Myrbetriq drug interactions

Myrbetriq can interact with other medications including:

  • Treatments for abnormal heart rhythm – propafenone or flecainide
  • Beta-blockers – carvedilol, propranolol, metoprolol, timolol
  • Drugs metabolized By CYP2D6 – desipramine
  • Digoxin
  • Other medications for an abnormal heart rhythm – quinidine, sotalol, procainamide, ibutilide, flecainide, dofetilide, or amiodarone
  • Certain blood thinners, such as warfarin, dabigatran etexilate
  • Antipsychotic medicines – thioridazine, mesoridazine, haloperidol, or chlorpromazine
  • Medications for allergic rhinitis

Before taking Myrbetriq, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Myrbetriq warnings & precautions

Don’t take Myrbetriq if:

  • Are allergic to the active ingredient mirabegron
  • Have had an allergic reaction to any of the other ingredients in Myrbetriq
  • If you have high blood pressure that is not controlled
  • Are under 18 years of age
  • Are pregnant or trying to become pregnant

Talk to your doctor before taking Myrbetriq if you:

  • Take any other medications for an overactive bladder
  • Have glaucoma
  • Have other bladder problems (such as blockage)
  • Have trouble emptying your bladder or have a weak urine stream
  • Have any liver problems or kidney problems
  • Have an ECG (heart tracing) abnormality called QT prolongation
  • Are breastfeeding or plan to breastfeed – It is unknown if this medication passes into breast milk

You should always check with your doctor or pharmacist before taking any medication, including Myrbetriq, to make sure it is safe for you.

Other warnings you should know about

  • Myrbetriq may increase your risk of urinary retention (trouble passing urine or not fully emptying the bladder), especially when used with another medicine (solifenacin succinate)
  • Urinary retention has also been reported in patients with bladder outlet obstruction (BOO)
  • Serious allergic reactions, called angioedema, which can be life-threatening and requires immediate medical attention have been reported. Stop treatment and get emergency medical help if you have signs of an allergic reaction (hives, trouble breathing, swelling of your face, lips, tongue, or throat)

How to avoid Myrbetriq side effects

The best way to avoid side effects is to take Myrbetriq as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Myrbetriq that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Drink plenty of fluids

If you have diarrhea with Myrbetriq may make you lose more fluids than usual if you have diarrhea. Drink plenty of fluids to avoid getting dehydrated.

3. Avoid alcohol

Alcohol does not affect how mirabegron works. Alcohol however can make your symptoms of urinary frequency and urgency worse.

4. Know the signs and symptoms of Myrbetriq side effects

Signs and symptoms of side effects include hypertension, nasopharyngitis, and urinary tract infection. If you experience any of these symptoms talk to your doctor.

5. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with Myrbetriq.

6. Get regular medical checkups

If you have an overactive bladder it is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your side effects and may adjust your dose of Myrbetriq as needed.

Mounjaro side effects and how to avoid them

Mounjaro is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Eli Lilly and Co. Mounjaro is classed as a GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist. Mounjaro is used to treat adults with type 2 diabetes mellitus.

While Mounjaro is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Mounjaro include nausea, vomiting, and diarrhea. Less common, but more serious side effects, can include inflammation of your pancreas, kidney problems, and thyroid tumors.

Learn more about the side effects of Mounjaro and what you can do to avoid them.

What is Mounjaro (tirzepatide)?

The active ingredient in Mounjaro is tirzepatide, a GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist. GIP decreases food intake and increases energy expenditure which causes weight loss. When taken with a GLP-1 receptor agonist, it may result in greater positive effects on blood glucose and body weight.

Mounjaro is used to treat adults with type 2 diabetes mellitus. It is not for use in people with type 1 diabetes, pancreatitis, or to treat children under 18 years of age.

Always check with your doctor or pharmacist before taking any medication, including Mounjaro, to make sure it is safe for you.

Mounjaro dosage

Mounjaro is available in injection form, in the following doses: 2.5 mg/0.5 mL, 5 mg/0.5 mL, 7.5 mg/0.5 mL, 10 mg/0.5 mL, 12.5 mg/0.5 mL, or 15 mg/0.5 mL single-dose pens.

Use the Mounjaro Pen to inject into the abdomen, thigh, or upper arm once weekly. This can be done independently of meals. If you miss a dose, take the missed dose as soon as possible within 96 hours after the missed dose. If more than 4 days have passed, skip the missed dose and take your next dose on your regularly scheduled day. Rotate your injection site with each weekly injection.

Use Mounjaro alongside dietary changes and exercise to improve glycemic control and always speak with a healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Keep this medicine in the refrigerator. Do not freeze. You may also store this medication at room temperature but remember to use it within 21 days.

How effective is Mounjaro?

FDA approval for Mounjaro was based on the SURPASS study, which compared Mounjaro with Ozempic, insulin glargine, semaglutide 1 mg, and insulin degludec. Participants who took Mounjaro experienced an average reduction in hemoglobin A1c, (an indicator of blood sugar level). Participants who took a placebo saw an average increase in A1C levels. Clinical trials of Mounjaro have also exceeded expectations both in its ability to lower A1C and to promote weight loss in people who are overweight or have obesity.

Mounjaro side effects

The most common possible side effects of Mounjaro include:

  • Nausea, vomiting
  • Diarrhea, decreased appetite, constipation, indigestion, abdominal pain

Mounjaro can cause more serious side effects, including:

  • Possible thyroid tumors, including thyroid cancer – do not use Mounjaro if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, have difficulty swallowing, or shortness of breath
  • Inflammation of your pancreas (pancreatitis) – symptoms include severe pain in your stomach area that will not go away, with or without vomiting
  • Low blood sugar (hypoglycemia) – Your risk for low blood sugar may be increased if you use Mounjaro with another diabetes medication such as a sulfonylurea or insulin
  • Serious allergic reactions
  • Kidney problems
  • Severe stomach problems
  • Changes in vision
  • Gallbladder problems

If you experience any of these serious side effects, stop taking Mounjaro and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Mounjaro drug interactions

Mounjaro can interact with other medications including:

  • Insulin secretagogue – sulfonylurea or Insulin
  • Oral medications
  • Orally administered hormonal contraceptives

Before taking Mounjaro, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Mounjaro warnings & precautions

Don’t take Mounjaro if:

  • Are allergic to the active ingredient tirzepatide
  • Are allergic to any of the other ingredients in Mounjaro

Talk to your doctor before taking Mounjaro if you:

  • Are taking any of the medications that could interact with Mounjaro
  • Have a history of diabetic retinopathy
  • Have pancreatitis, gallbladder disease, kidney problems, or severe stomach problems
  • Are pregnant or plan to become pregnant – If you take oral birth control pills by mouth, you may be recommended another type of birth control for 4 weeks after you start Mounjaro and for 4 weeks after each increase in your dose
  • Are breastfeeding or planning to breastfeed. It is not known if Mounjaro passes into your breast milk

You should always check with your doctor or pharmacist before taking any medication, including Mounjaro, to make sure it is safe for you.

Other warnings you should know about

In clinical studies, tirzepatide causes thyroid C-cell tumors in rats. It is not known whether Mounjaro causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans. Mounjaro is contraindicated in those patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

How to avoid Mounjaro side effects

The best way to avoid side effects is to take Mounjaro as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Mounjaro that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Mounjaro. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Mounjaro as it can increase your risk of side effects.

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia), or high blood sugar levels (hyperglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Mounjaro.

7. Know the signs and symptoms of Mounjaro side effects

Signs and symptoms of side effects include nausea, vomiting, and diarrhea. If you experience any of these symptoms speak to your doctor for medical advice.

8. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Mounjaro.

9. Get regular medical checkups

If you have diabetes it is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your blood sugar levels and may adjust your dose of Mounjaro as needed.

Nurtec ODT side effects and how to avoid them

Nurtec ODT is a medication manufactured by Biohaven Pharmaceuticals Inc. Nurtec ODT is the brand name for the prescription drug rimegepant sulfate. It has FDA approval (Food and Drug Administration) for the acute treatment of migraine attacks, with or without aura, in adults. It is also used as a preventive treatment for episodic migraine headaches. While Nurtec ODT is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Nurtec ODT include nausea and indigestion. Less common, but more serious side effects, can include allergic reactions.

Learn more about the side effects of Nurtec ODT and what you can do to avoid them.

What is Nurtec ODT (rimegepant)?

Nurtec ODT is a migraine medication used for the acute treatment of migraine attacks, with or without aura, in adults. It is also used for episodic migraine prevention. The active ingredient of Nurtec ODT is rimegepant. It is classed as a calcitonin gene-related peptide (CGRP) receptor antagonist. Calcitonin gene-related peptide (CGRP) inhibitors block the effect of CGRP. CRGP is a small protein that is widespread in the sensory nerves that supply the head and neck. CRGP is involved in the transmission of pain, and its levels increase during a migraine attack. CRGP may also play a part in the onset of migraine attacks.

Always check with your doctor or pharmacist before taking any medication, including Nurtec ODT, to make sure it is safe for you.

More information on What is Nurtec ODT

Nurtec ODT dosage

Nurtec ODT is available in the following dosage form: orally disintegrating tablets, in doses of 75 mg. The recommended dose of Nurtec ODT is 75 mg orally as needed. The maximum dose in a 24-hour period is 75 mg.

This medication comes in a blister pack. Make sure your hands are dry when you are ready to take a dose. Place the tablet either on or under your tongue and allow it to dissolve. You do not need to take this medication with water or other liquid. Do not store this medication outside the blister pack for future use. Store at room temperature away from light and moisture.

Please read the prescribing information provided with this medicine for the full drug information and further patient information, and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

More information on Nurtec ODT dosage

How effective is Nurtec ODT?

Studies have found that individuals taking Nurtec ODT for migraine prevention experience migraine symptoms less regularly than before starting treatment.

Nurtec ODT side effects

The most common possible side effects of Nurtec ODT include:

  • Nausea – with continued use of Nurtec ODT this side effect may go away. However, nausea is also a common migraine symptom
  • Stomach pain, indigestion

Nurtec ODT can cause more serious side effects, including:

  • Trouble breathing
  • Hives, rash, difficulty breathing, swelling of your face, lips, tongue, or throat

If you experience any of these serious side effects, stop taking Nurtec ODT and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Nurtec ODT drug interactions

Nurtec ODT can interact with other medications including:

  • Strong inhibitors of CYP3A4 – clarithromycin, erythromycin, verapamil, grapefruit
  • Strong or moderate inducers of CYP3A – phenobarbital, phenytoin, rifampicin, St. John’s Wort
  • Inhibitors of P-gp or BCRP – amiodarone, ciclosporin, diltiazem, lansoprazole, ritonavir, nelfinavir
  • Azole antifungals – fluconazole, ketoconazole, itraconazole)
  • Rifamycins – rifampin, rifabutin

Before taking Nurtec ODT, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Nurtec ODT warnings & precautions

Don’t take Nurtec ODT if:

  • Are allergic to the active ingredient rimegepant
  • You have had an allergic reaction to any of the other ingredients in Nurtec ODT

Talk to your doctor before taking Nurtec ODT if you:

  • Are taking any of the medications that could interact with Nurtec ODT
  • Have liver problems
  • Have kidney disease or any other kidney problems
  • Are pregnant or plan to become pregnant – your doctor will recommend appropriate treatment options for you. It is not known if Nurtec ODT can harm your unborn baby
  • Are breastfeeding or are planning to breastfeed – It’s also not known if Nurtec ODT passes into breast milk or if it can affect a child who is breastfed. Talk with your doctor about the possible risks and benefits of taking Nurtec ODT while breastfeeding

You should always check with your doctor or pharmacist before taking any medication, including Nurtec ODT, to make sure it is safe for you.

Other warnings you should know about

Hypersensitivity reactions such as rash and dyspnea can occur days after taking Nurtec ODT, Discontinue Nurtec ODT if a hypersensitivity reaction occurs.

How to avoid Nurtec ODT side effects

The best way to avoid side effects is to take Nurtec ODT as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Nurtec ODT that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Drink plenty of fluids

Nurtec ODT can be taken without water, however, if you do get migraines it’s important you drink plenty of water as staying hydrated may help you prevent a migraine attack.

3. Avoid alcohol

There isn’t any known interaction between drinking alcohol and taking Nurtec ODT. However, alcohol can trigger a migraine attack in some people. It may be best to avoid drinking alcohol while taking the drug if alcohol is one of your triggers.

4. Know the signs and symptoms of Nurtec ODT side effects

Signs and symptoms of side effects include nausea and stomach pain. Speak to your doctor if you experience any of these side effects.

5. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Nurtec ODT.

Skyrizi side effects and how to avoid them

Skyrizi is a brand-name medication that is manufactured by AbbVie Inc. It is classed as an interleukin-23 biologic and used for the treatment of moderate-to-severe plaque psoriasis or active psoriatic arthritis, and moderate to severe Crohn’s disease in adults who are candidates for systemic therapy or phototherapy. While Skyrizi is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Skyrizi include headaches, tiredness, and stomach pain. Less common, but more serious side effects, can include an increased risk of serious infections and allergic reactions.

Learn more about the side effects of Skyrizi and what you can do to avoid them.

What is Skyrizi (risankizumab-rzaa)?

The active ingredient in Skyrizi is called risankizumab-rzaa. It is a type of antibody protein that has been designed to specifically target and deactivate immune system proteins that cause inflammation.

One of the ways your immune system triggers inflammation is by releasing interleukin proteins. Interleukins are created and released by your white blood cells. They then attach to the outside of certain cells in your body (such as skin cells), triggering the cells to begin processes that cause inflammation.

When you take Skyrizi, the risankizumab it contains attaches to the interleukins released by your white blood cells. This blocks the interleukins, stopping them from attaching to skin cells and triggering inflammation. In turn, this limits how much inflammation your immune system can cause in your skin, reducing the severity of your plaques and clearing areas of your skin. Learn more about what is Skyrizi.

Skyrizi dosage

Skyrizi is available in injection form, in single-dose prefilled syringes, each containing 75 mg/0.83 mL. 150 mg (two 75 mg injections) of Skyrizi is administered by subcutaneous injection at Week 0, Week 4, and every 12 weeks thereafter. Your doctor will show you how much Skyrizi to use and how often.

Adults with plaque psoriasis or psoriatic arthritis will receive Skyrizi using the prefilled pen or prefilled syringe. Adults with Crohn’s disease will receive starter doses through a vein in the arm in a healthcare setting by a healthcare provider. After completing the starter doses, these patients will receive Skyrizi as a subcutaneous injection using the prefilled cartridge with on-body injector.

If you miss a dose of Skyrizi, inject a dose as soon as you remember, and take your next dose at your scheduled time. If you use more Skyrizi than prescribed, call your healthcare provider immediately.

Store Skyrizi in the original carton in a refrigerator and use it until its expiration date. Protect from light. Do not shake or freeze. When using Skyrizi, take the medicine out of the refrigerator and allow it to reach room temperature for 30 to 90 minutes before use. Do not heat the medicine in any other way.

You are advised to read the medication guide for the full prescribing information and drug information and to always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

How effective is Skyrizi?

In clinical studies comparing adults with plaque psoriasis using Skyrizi to those using a placebo, after 16 weeks 75% of adults receiving Skyrizi reported at least a 90% improvement in their plaque psoriasis symptoms, compared to 2% to 5% of those receiving a placebo reporting a 90% improvement in their plaque psoriasis symptoms.

Skyrizi side effects

The most common possible side effects of Skyrizi in clinical trials include:

  • Cold symptoms such as stuffy nose, sneezing, sore throat
  • Headaches
  • Tiredness
  • Injection site reactions: swelling, itching, and pain at the site of injection
  • Upper respiratory infections, fever, stomach pain, back pain, joint pain, and low red blood cells (anemia)
  • An increased risk of fungal skin infections

Skyrizi can cause more serious side effects, including:

  • Increased risk of serious infections such as tuberculosis (fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired)
  • Severe allergic reactions to the medication

If you experience any of these serious side effects, stop taking Skyrizi and seek medical attention immediately. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Skyrizi drug interactions

Skyrizi can interact with other medications including:

  • Any other treatments you have for your psoriasis
  • Any vaccinations you are due to have or have recently had

Before taking Skyrizi, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Skyrizi warnings & precautions

You should not use Skyrizi if:

  • Are allergic to the active ingredient risankizumab
  • Are allergic to any of the other ingredients in Skyrizi
  • Are under 18 years of age

Talk to your doctor before taking Skyrizi if you:

  • Are taking any of the medications that could interact with Skyrizi
  • Have tuberculosis or have recently been around someone who has tuberculosis
  • Have an infection that will not go away or that keeps coming back
  • Have recently had a live vaccine or are due to have one
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known if Skyrizi passes into your breast milk

You should always check with your doctor or pharmacist before taking any medication, including Skyrizi, to make sure it is safe for you.

Other warnings you should know about

  • Skyrizi may reduce the ability of your immune system to fight infections and may increase your risk of infections. Call your doctor if you have symptoms such as fever, chills, sweats, muscle aches, skin sores, stomach pain, diarrhea, burning when you urinate, weight loss, cough, trouble breathing, shortness of breath, or a cough with red or pink mucus
  • Skyrizi can cause serious allergic reactions. Stop using this medicine and get emergency medical help if you get any of the following symptoms – fainting, dizziness, feeling lightheaded, swelling of your face, eyelids, lips, mouth, tongue, or throat, trouble breathing or throat or chest tightness, skin rash, hives, or itching

How to avoid Skyrizi side effects

The best way to avoid side effects is to take Skyrizi as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Skyrizi that has been recommended by your healthcare professional. Do not take more or less than specified.

2. Alcohol

Skyrizi is not known to interact with alcohol, however, research shows that alcohol can trigger a new diagnosis of psoriasis or make symptoms worse.

3. Know the signs and symptoms of Skyrizi side effects

Signs and symptoms of side effects include upper respiratory infection, headaches, and tiredness. Speak to your doctor for medical advice if you experience any of these side effects.

4. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Skyrizi.

5. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your progress and may adjust your dose of Skyrizi as needed.

Invega side effects and how to avoid them

Invega is a brand-name medication manufactured by Janssen Pharmaceuticals, Inc. It is classed as an atypical antipsychotic drug used to treat mental health conditions such as schizophrenia in adults and adolescents aged 12 to 17 and schizophrenia disorder in adults. Invega helps ease the symptoms of schizophrenia and schizoaffective disorder and can prevent symptoms from recurring. While Invega is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Invega include drowsiness and dizziness. Less common, but more serious side effects, can include severe allergic reactions, high blood sugar, and weight gain.

Learn more about the side effects of Invega and what you can do to avoid them.

What is Invega (paliperidone)?

Invega is a brand-name medication manufactured by Janssen Pharmaceuticals, Inc. It is classed as an atypical antipsychotic for the treatment of schizophrenia or schizoaffective disorder. The active ingredient in Invega is called paliperidone, which can reduce the symptoms of psychotic episodes caused by schizophrenia or bipolar disorder.

When Invega is taken, it is absorbed into your blood and transported to your brain. It then binds with areas on the outside of your brain cells called dopamine and serotonin receptors. Dopamine and serotonin are chemicals that influence and regulate your brain activity, including your experience of pleasure, motivation, reward pathways, thinking, memory, and mood.

By binding with your dopamine and serotonin receptors, paliperidone reduces the effect of dopamine and serotonin on your brain. This has been shown to ease the symptoms of schizophrenia and schizoaffective disorder and to help stop periods of psychosis and mood change from happening.

Always check with your doctor or pharmacist before taking any medication, including Invega, to make sure it is safe for you.

Invega dosage

Invega is available as extended-release tablets, in doses of 1.5 mg, 3 mg, 6 mg, and 9 mg. Your initial recommended and maximum dose of Invega will be based on your condition, age, and your body weight. Typically this will be higher if you are an adult. Invega tablets should be swallowed whole, not chewed, divided, or crushed. If you miss a dose of Invega, take it as soon as you remember. Skip the missed dose if it is near the time of your next dose. Do not double your doses to catch up.

Invega is also available as Invega Sustenna, Invega Trinza, and Invega Hafyera. Invega Sustenna is a long-acting injection. Whereas Invega tablets are taken as a daily pill, Invega Sustenna is given to you as an intramuscular injection (into the deltoid muscle of the arm or the gluteal muscle of the buttocks) by a healthcare professional, usually once a month. Invega Sustenna is released into your system over the course of a month. It may be more suitable for you than a daily oral medication if you struggle to take your medication consistently. Your healthcare provider will decide if and what dose of Invega Sustenna you will need based on your condition and medical history.

Invega Trinza and Invega Hafyera may be used if you have already been treated with Invega Sustenna for at least 4 months. Invega Hafyera may also be used if you have been treated with Invega Trinza for at least 3 months.

You are advised to read the full prescribing and drug information for Invega and to always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Invega side effects

The side effects caused by Invega will vary by person and in line with the condition which they’re taking it for. It will also depend if it is injected or taken in pill form. Some of the common side effects caused by Invega include:

The most common side effects of Invega include:

  • Drowsiness, sedation, sleepiness
  • Lightheadedness, dizziness
  • Restlessness
  • Gastrointestinal disorders such as constipation, dry mouth, dyspepsia, abdominal pain, flatulence, salivary hypersecretion
  • Unusual muscle movements and tremors
  • Abnormal movements of your eyes

Invega can cause more serious side effects, including:

  • Severe allergic reactions to the medication causing heart palpitations, sweating, fever, skin rashes, and hives, as well as swelling of the face, mouth, and throat that can make it difficult to breathe
  • A rare but potentially fatal condition called neuroleptic malignant syndrome (NMS) caused by an unusual response to antipsychotic medications
  • Cardiovascular risks such as irregular heartbeat, including palpitations, skipped beats, and slowing down or speeding up of your heart rate, can cause problems with your heart or make existing heart conditions worse, like heart failure
  • Extrapyramidal symptoms – uncontrolled movements of your tongue, face, mouth, jaw (tardive dyskinesia), and lip-smacking
  • Akathisia (an uncontrollable urge to move around)
  • Muscle stiffness, muscle spasms, pain, tenderness, or weakness
  • High blood sugar (diabetes)
  • Anemia, decreased hematocrit, low white blood cell count, thrombocytopenia
  • Weight gain and a rise in your blood cholesterol (or triglyceride) levels
  • Orthostatic hypotension (low blood pressure that can cause fainting)
  • Seizures
  • Problems regulating your body temperature can make you overheat and become dehydrated
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors
  • Difficulty swallowing can cause food or liquid to get into your lungs
  • A long-lasting erection (priapism) in men can lead to permanent damage to the penis
  • Hyperprolactinemia (high prolactin levels in the blood)

If you experience any of these serious side effects, stop taking Invega and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Invega drug interactions

Invega can interact with other medications including:

  • Any other antipsychotic medications
  • Any antidepressant medications
  • Risperidone – an antipsychotic used to treat schizophrenia and bipolar disorder
  • Valproate – used to treat epilepsy, bipolar disorder, and migraines
  • Any psychostimulants, like methylphenidate
  • Medications that can alter your dopamine and serotonin levels
  • Any antihistamines
  • Any antimalarial medications
  • Any medications you take to treat high blood pressure, like diuretics, alpha-blockers, beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, or calcium channel blockers
  • Medications for Parkinson’s disease
  • Medications for levodopa (restless leg syndrome)
  • Any other medications that can affect how your brain functions
  • Any nitrate medications, usually taken to treat chest pain (angina)
  • Any antiviral medications taken to treat an HIV infection, including saquinavir
  • Any antibiotics taken to treat a bacterial infection, including rifampicin, clarithromycin, or telithromycin
  • Any antifungal medications taken to treat a fungal infection, including ketoconazole
  • Any anticonvulsant medications taken to reduce the chances of you having seizures, like carbamazepine, phenobarbital, or phenytoin
  • QT-prolongation medications, such as amiodarone, clarithromycin, domperidone
  • St John’s-wort

Before taking Invega, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Invega warnings & precautions

Don’t take Invega if:

  • Are allergic to the active ingredient paliperidone, or to risperidone
  • Are allergic to any of the other ingredients in Invega
  • Are over 65 and have dementia – antipsychotic medications cause an increased risk of stroke and death in elderly patients with dementia-related psychosis

Talk to your doctor before taking Invega if you:

  • Are taking any medications that can interact with Invega (listed in the section above)
  • Have ever had any heart problems like heart disease, a heart attack, arrhythmias, or an abnormal heart rhythm
  • Have ever had neuroleptic malignant syndrome
  • Have ever experienced movement disorder of the face and tongue (tardive dyskinesia)
  • Have ever had low levels of white blood cells
  • Have ever had low levels of potassium or magnesium in your blood
  • Have kidney problems
  • Have liver problems
  • Parkinson’s disease
  • Are diabetic or are at risk of diabetes
  • Have ever had priapism (a prolonged and painful erection)
  • Have difficulty controlling your core body temperature, or are prone to overheating
  • Have a high level of the hormone prolactin in your blood or have a prolactin-dependent tumor
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Invega, to make sure it is safe for you.

Other warnings you should know about

  • Invega can cause side effects like drowsiness, and dizziness that can impair your ability to operate machinery, drive, or perform other dangerous tasks. Avoid these activities when treated with Invega until you are sure it does not affect your ability to do them safely
  • Invega is not approved for the treatment of dementia-related psychosis. Older adults who have dementia-related psychosis are at an increased risk of death
  • It is not known if Invega is safe to use while breastfeeding. The drug can pass into breast milk, and may have undesirable side effects

How to avoid Invega side effects

The best way to avoid side effects is to take Invega as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the adverse effects.

1. Stick to the recommended dosage

Take your prescribed dose of Invega that has been recommended by your healthcare professional. Do not use more or less than specified.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while using Invega. Tell your doctor if you have symptoms of high blood sugar such as increased thirst or urination. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Avoid alcohol

Avoid drinking alcohol while taking Invega as it can increase your risk of side effects like dizziness, drowsiness, and trouble concentrating. This may affect your ability to think clearly.

4. Know the signs and symptoms of Invega’s side effects

Signs and symptoms of side effects include drowsiness, sleepiness, feeling light-headed, dizziness, or unusual muscle movements. Speak to your doctor if you experience any of these side effects.

5. Monitor your weight

Invega may cause weight gain. If you experience this side effect get medical advice from your doctor.

6. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Invega.

7. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your progress and may adjust your dose as needed.

Invega Sustenna side effects and how to avoid them

Invega Sustenna is a brand-name medication manufactured by Janssen Pharmaceuticals, Inc. It is classed as an atypical antipsychotic drug used to treat schizophrenia or schizoaffective disorder. While Invega Sustenna is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Invega Sustenna include drowsiness, dizziness, and reactions at the injection site. Less common, but more serious side effects, can include severe allergic reactions, high blood sugar, and weight gain.

Learn more about the side effects of Invega Sustenna and what you can do to avoid them.

What is Invega Sustenna (paliperidone palmitate)?

Invega Sustenna is a brand-name medication manufactured by Janssen Pharmaceuticals, Inc. It is classed as an atypical antipsychotic for the treatment of schizophrenia or schizoaffective disorder. The active ingredient in Invega Sustenna is called paliperidone, which can reduce the symptoms of psychotic episodes caused by schizophrenia or bipolar disorder.

When Invega Sustenna is injected, it is absorbed into your blood and transported to your brain. It then binds with areas on the outside of your brain cells called dopamine and serotonin receptors. Dopamine and serotonin are chemicals that influence and regulate your brain activity, including your experience of pleasure, motivation, reward pathways, thinking, memory, and mood.

By binding with your dopamine and serotonin receptors, paliperidone reduces the effect of dopamine and serotonin on your brain. This has been shown to ease the symptoms of schizophrenia and schizoaffective disorder and to help stop periods of psychosis and mood change from happening.

Invega Sustenna dosage

Invega Sustenna is a long-acting injection. Whereas many antipsychotic medications are taken as a daily pill, Invega Sustenna is given to you as an intramuscular injection (into the deltoid muscle of the arm or the gluteal muscle of the buttocks) by a healthcare professional, usually once a month. Invega Sustenna is released into your system over the course of a month. It may be more suitable for you than a daily oral medication if you struggle to take your medication consistently. Your healthcare provider will decide what dose of Invega Sustenna you will need based on your condition and medical history.

Invega is available as extended-release tablets. Invega Trinza and Invega Hafyera may be used if you have been treated with Invega Sustenna for at least 4 months. Invega Hafyera may also be used if you have been treated with Invega Trinza for at least 3 months. You will need to receive a second dose of Invega Sustenna 1 week after your first dose. After that, you will only need to get a dose once monthly. Invega Trinza will be given to you once every 3 months and Invega Hafyera once every 6 months.

If you miss a dose of Invega Sustenna call your doctor for instructions. You are advised to read the full prescribing information and to always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

How effective is Invega Sustenna?

A study called the PRIDE study has shown that long-acting Invega Sustenna (paliperidone palmitate) is effective six months longer than oral antipsychotics in patients with schizophrenia, delaying relapses such as hospitalization, arrest, and incarceration.

Invega Sustenna side effects

The most common possible side effects of Invega Sustenna include:

  • Reactions at the site of injection, including itching, bruising, and pain
  • Drowsiness, sleepiness
  • Lightheadedness, dizziness
  • Restlessness
  • Gastrointestinal disorders such as constipation, dry mouth, dyspepsia, flatulence, salivary hypersecretion
  • Unusual muscle movements and tremors
  • Abnormal movements of your eyes

Invega Sustenna can cause more serious side effects, including:

  • Severe allergic reactions to the medication causing heart palpitations, sweating, fever, skin rashes, and hives, as well as swelling of the face, mouth, and throat that can make it difficult to breathe
  • A rare but potentially fatal condition called neuroleptic malignant syndrome (NMS) caused by an unusual response to antipsychotic medications
  • Irregular heartbeat, including palpitations, skipped beats, and slowing down or speeding up of your heart rate, can cause problems with your heart or make existing heart conditions worse, like heart failure
  • Extrapyramidal symptoms – uncontrolled movements of your tongue, face, mouth, or jaw (tardive dyskinesia)
  • Muscle stiffness, muscle spasms, pain, tenderness, or weakness
  • High blood sugar (diabetes)
  • Weight gain and a rise in your blood cholesterol (or triglyceride) levels
  • Orthostatic hypotension (low blood pressure that can cause fainting)
  • Seizures
  • Problems thinking clearly
  • Problems regulating your body temperature can make you overheat and become dehydrated
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors
  • Difficulty swallowing can cause food or liquid to get into your lungs
  • A long-lasting erection (priapism) in men can lead to permanent damage to the penis
  • Hyperprolactinemia (high prolactin levels in the blood)

If you experience any of these serious side effects, stop taking Invega Sustenna and seek medical attention immediately. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Invega Sustenna drug interactions

Invega Sustenna can interact with other medications including:

  • Any antidepressant medications
  • Any nitrate medications, usually taken to treat chest pain (angina)
  • Any medications you take to treat high blood pressure, like diuretics, alpha-blockers, beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, or calcium channel blockers
  • Any antiviral medications taken to treat an HIV infection, including saquinavir
  • Any antibiotics taken to treat a bacterial infection, including rifampicin, clarithromycin, or telithromycin
  • Any antifungal medications taken to treat a fungal infection, including ketoconazole
  • Any anticonvulsant medications taken to reduce the chances of you having seizures, like carbamazepine, phenobarbital, or phenytoin
  • QT-prolongation medications, such as amiodarone, clarithromycin, domperidone
  • St John’s-wort

Before taking Invega Sustenna, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Invega Sustenna warnings & precautions

Don’t take Invega Sustenna if:

  • Are allergic to the active ingredient paliperidone, or risperidone
  • Are allergic to any of the other ingredients in Invega Sustenna
  • Are over 65 and have dementia-related psychosis
  • Are under 18 years of age

Talk to your doctor before taking Invega Sustenna if you:

  • Are taking any of the medications that could interact with Invega Sustenna
  • Have ever had any heart problems like heart disease, a heart attack, arrhythmias, or an abnormal heart rhythm
  • Have ever had neuroleptic malignant syndrome
  • Have ever experienced movement disorder of the face and tongue (tardive dyskinesia)
  • Have ever had low levels of white blood cells
  • Have ever had low levels of potassium or magnesium in your blood
  • Have kidney problems
  • Have liver problems
  • Parkinson’s disease
  • Are diabetic or are at risk of diabetes
  • Have ever had priapism (a prolonged and painful erection)
  • Have difficulty controlling your core body temperature, or are prone to overheating
  • Have a high level of the hormone prolactin in your blood or have a prolactin-dependent tumor
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should always check with your doctor or pharmacist before taking any medication, including Invega Sustenna, to make sure it is safe for you.

Other warnings you should know about

  • Invega Sustenna can cause side effects like drowsiness, and dizziness that can impair your ability to operate machinery, drive, or perform other dangerous tasks. Avoid these activities when treated with Invega Sustenna until you are sure it does not affect your ability to do them safely
  • Invega Sustenna is not approved for the treatment of dementia-related psychosis. Elderly patients who have dementia-related psychosis are at an increased risk of death
  • It is not known if Invega is safe to use while breastfeeding. The drug can pass into breast milk, and may have undesirable side effects

How to avoid Invega Sustenna side effects

The best way to avoid side effects is to take Invega Sustenna as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Invega Sustenna that has been recommended by your healthcare professional. Do not use more or less than specified.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while using Invega Sustenna. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Avoid alcohol

Avoid drinking alcohol while taking Invega Sustenna as it can increase your risk of side effects like dizziness, drowsiness, and trouble concentrating. This may affect your ability to think clearly.

4. Know the signs and symptoms of Invega Sustenna’s side effects

Signs and symptoms of side effects include drowsiness, sleepiness, feeling light-headed, dizziness, or unusual muscle movements. Speak to your doctor if you experience any of these side effects.

5. Monitor your weight

Invega Sustenna may cause weight gain. If you experience this side effect while taking Invega Sustenna, get medical advice from your doctor.

6. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Invega Sustenna.

7. Get regular medical checkups

It is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your progress and may adjust your dose of as needed.

Mental Health Report

The effects of the COVID-19 pandemic has had a huge impact on everyone’s mental health, and this has in turn put a strain on support services, and suspended social interactions have left many Americans feeling isolated and alone. An increasing number of adults have developed anxiety over the last two years.

At NiceRx, we have found that anxiety medication has helped people to feel calmer on a daily basis, as well as psychotherapy, which is often used in combination with medication to treat anxiety disorders. What works for some may not work for others, and medication may be more useful to others, and not so useful for some, who find psychotherapy the best option. A combination of treatment is often better than either alone.

So what do mental health services look like in the post-COVID world? With the rise of online therapy, is it possible to develop a response to those who are suffering? We explored which US states have had the most demand for mental health support.

The States Spending the Most on Mental Health Funding

States spending most on mental health map

1. Maine – Spending per Capita: $345.36

Every US state has a significant degree of power to make decisions about their mental health care systems. However, they must adhere to regulations to meet standards put in place by the federal government.

Maine is an example of one state that has expanded its mental health systems beyond the federal level to improve access to mental health care and offer better services. Maine is the US state with the largest budget allocated to mental health funding ($345.36).

2. Alaska – Spending per Capita: $341.08

Alaska comes in a close second as the US state with the largest budget allocated to mental health funding with $341.08 spending per capita. It was reported in 2021 that Alaska’s mental health crisis had a particularly harder impact on minorities.

3. District of Columbia – Spending per Capita: $306.87

The District of Columbia takes third place with $306.87 spending per capita. Adults who need behavioral health services and support can choose from a number of community-based private providers located in neighborhoods throughout the District.

The bottom three states with the lowest budgets allocated for mental health include Arkansas with $45.56, Texas with $40.65, and Idaho with $32.77 spending per capita.

States spending the most on mental health

The States with the Highest Mental Health Prevalence

This data refers to adults with any kind of mental illness, adults with a substance use disorder, adults with thoughts of suicide, and much more factors.

19.86% of adults are experiencing a mental illness. Equivalent to nearly 50 million Americans:

States with the highest mental health prevalence map

1. Utah

% of Adults with a Mental Health Illness: 26.86%

Utah had the highest prevalence of adults with a mental health illness (26.86%). In a 2017 study, one in five adults in Utah experiences poor mental health.

2. West Virginia

% of Adults with a Mental Health Illness: 24.62%

West Virginia had the second highest prevalence of adults with a mental health illness (24.62%). Experts have reported that West Virginia’s poor mental health stems from high rates of poverty and substance use, along with a deep rooted culture of independence that condemns psychological help.

3. Oregon

% of Adults with a Mental Health Illness: 23.75%

Oregon is the third state with the highest prevalence of adults with mental health illnesses (23.75%). A study in 2021 revealed that 34.6% of adults in Oregon reported symptoms of anxiety and/or depressive disorder, compared to 31.6% of adults in the US.

States with highest mental health prevalence

The States Paying the Most for Therapy

In the US, the median rate for a therapy session in 2017 was $120. The rates by state varied considerably, ranging from $70 in Florida to $160 in Alaska:

Map of states paying the most for therapy

1. Alaska – Median Therapy Session Rate – $160

Alaska is the state where residents pay the most for therapy sessions. Data from Sample Practice, a practice management system for mental health professionals, revealed that session rates in Alaska were around $160 per session.

2. Arkansas, Hawaii, Illinois, Iowa, New Jersey & Washington DC

Median Therapy Session Rate – $150 

These states were the second highest priced states for therapy sessions. It was found that residents should expect to pay $150+ for a single therapy session.

10 states (Connecticut, New Hampshire, Pennsylvania, Rhode Island, Vermont, Alabama. Maryland, California, Oregon, and Wyoming) had rates at $120.

Five states (Florida, Indiana, Michigan, Missouri, and Ohio) had median rates at or below $90.

States paying the most for therapy

The States Searching the Most for Therapists

By exploring Google search data, we were able to find the states that had been searching for therapists the most in the last year. These were the results:

Map of states searching for most therapists

1. Florida – 43,414.67 Searches per 100,000

Florida saw the highest volume of Google searches for ‘therapists’ with nearly over 43,000 yearly searches. It was reported that there are more than 37,000 therapists in Florida, and as it is such a largely dense state, it is no wonder that many residents are searching for therapists.

2. Virginia –  19,424.69 Searches per 100,000

Virginia was the second state for the most therapists searches, with over 19,000 lookups in the last year. With over 24,000 therapists working in Virginia, it’s clear that there are a lot of residents using their services.

3. New York – 16,189.60 Searches per 100,000

New York is third on our list for its Google searches of ‘therapists’, with over 16,000 yearly searches. Home to New York City, a modern and forward-thinking place, it’s likely that there are plenty of online therapy sessions that are accessible to residents, hence its high volume of searches.

States searching the most for therapists

Top Tips for Improving Your Mental Health

It’s near impossible to feel great every day, with the pressures of life and the effects of the pandemic still lingering, it’s important we look after ourselves.

There are a few day-to-day activities you can practice to help improve your overall well-being without the need for medication, here are some tips shared by the experts at NiceRx:

Top tips for improving mental health

1. Connect with Friends and Family

Good relationships are important for your well-being and others too, so get talking with a loved one or a close friend. It can help you:

  • Build a sense of belonging and self-worth
  • Gives you an opportunity to share positive experiences
  • Provide emotional support and allow you to support others

2. Be Physically Active

There are thousands of studies proving that exercise is good for the body as well as the mind by:

  • Raising your self-esteem
  • Helping you to set goals and achieve them
  • Causing chemical changes in your brain which can help to positively change your mood

3. Learn New Skills

Research shows that learning new skills can improve your mental well-being by:

  • Boosting self-confidence and raising self-esteem
  • Helping you build a sense of purpose
  • Connecting with others

4. Give to others

More and more studies have suggested that acts of giving and kindness can help improve your mental well-being by:

  • Creating positive feelings and a sense of reward
  • Giving you a feeling of purpose and self-worth
  • Helping you to connect with others

5. Pay attention to the present moment (mindfulness)

By paying more attention to the present moment, you can improve your mental well-being. This includes your thoughts, feelings, body, and world around you.

Some people call this awareness “mindfulness”. Mindfulness can help you enjoy life more and understand yourself better. It can positively change the way you feel about life and how you approach challenges.

NiceRx can also assist with accessing FDA-approved brand-name medications, including Vyvanse, Viibryd, Mydayis, Intuniv and Qelbree.

Methodology

We started our research by using World Atlas’s report on States Who Spend The Most On Mental Health Funding to find each US state’s spending per capita on mental health funding.

We then used Simple Practice’s guide on the Average Therapy Session Rates to find the median rate of psychotherapy sessions in each state.

We looked at MHA National’s Adult Prevalence Of Mental Illness to find the prevalence of mental illness in each state.

Danger Drugs

Which states are experiencing the most drug overdoses and what are the most common drugs used in the US?

It is important to monitor drug overdose deaths in the US to understand the impact on the population and to see how the crisis is evolving, for better or worse.

That is why we have collected data from the CDC’s National Center for Health Statistics, which receives data from death certificates, including the cause of death information from medical examiners and coroners.

At NiceRx, we are concerned with helping people to access medications affordably and easily, so check out our affordable medication here.

US States with the Highest Drug Overdose Deaths

Most drug deaths by state

1. California – 39,156 Total Deaths 

California has seen the highest number of deaths caused by drug overdoses between the years of 2013 and 2020. A total of 39,156 deaths were recorded from 2013 to 2020, and the numbers are rising. From 2013 when 4,452 deaths were recorded, to 2020 when this figure doubled, to a concerning 8,908 deaths. It was reported in 2021 that in California, 8.5% of the overall population has an addiction to any substance (drugs or alcohol).

2. Georgia – 31,447 Total Deaths

Georgia falls second in our list of US states with the highest overdose deaths between 2013 and 2020. A total of 31,447 deaths caused by drugs were recorded during this period. Georgia saw a huge jump in the number of fatalities between 2014 and 2015 when the number more than doubled from 1,206 to 3,228. Fast forward to 2020, and 7,231 deaths were recorded.

3. Rhode Island – 27,486 Total Deaths

Rhode Island is in third place for its overdose deaths caused by drugs between 2013 and 2020. The state saw a huge increase in deaths (2044%) since 2013, and 27,486 deaths were recorded in the eight-year period. In 2013, just 241 deaths were recorded. In 2020, this number increased to 5,168 deaths caused by drug overdose.

4. Oklahoma – 26,962 Total Deaths

Oklahoma stands in fourth place for total overdose deaths caused by drugs in 2013-2020. The state saw a large increase in deaths (559%) since 2013, and 26,962 deaths were recorded during the period.

5. North Carolina – 23,950 Total Deaths

North Carolina falls in fifth place for the most overdose-related deaths in the eight-year period. The state has seen a 294% increase in deaths caused by drug overdoses since 2013, with 23,950 deaths recorded. It was found that heroin has played a huge part in the number of overdose deaths in North Carolina.

US states with most drug overdose

Drugs Causing the Most Deaths in the US

Top 5 deadliest drugs in us

1. Heroin – 48,579 Total Deaths

Heroin is the number one killer drug to cause overdose deaths in the US during the recorded eight-year period. The drug is a powerful opiate that’s usually sold as a white or brown powder.

The risk of overdose and death is high when using heroin, as it causes many users to become dependent on it, making it the most dangerous drug to become addicted to. With 48,579 deaths in the US alone, heroin has played a huge part in the opioid epidemic across the country.

2. Fentanyl –  32,728 Total Deaths 

Fentanyl is the second most dangerous drug in the US, with 32,728 Total Deaths. It is a synthetic opioid that is up to 50 times stronger than heroin and is a major contributor to fatal overdoses in the US.

It is a drug of abuse. Fentanyl (and other opioids) could possibly be used as an incapacitating agent to impair a person’s ability to function.

3. Cocaine – 29,851 Total Deaths

Cocaine is the third most dangerous drug, with 29,851 deaths caused by overdose between 2013 and 2016. Cocaine is a powerfully addictive stimulant drug made from the leaves of the coca plant native to South America.

While some people may see it as a recreational drug, it is possible to overdose on cocaine. An overdose occurs when a person uses enough of a drug to produce serious adverse effects, life-threatening symptoms, or death. According to NIDA, cocaine-related death totals have seen a significant fluctuation in the last decade or so.

4. Alprazolam – 18,971 Total Deaths

Alprazolam, often referred to as Xanax, is the fourth most dangerous drug in the US. Alprazolam is a prescription medication used to treat anxiety and panic disorder. The National Center for Drug Abuse Statistics (NCDAS) estimates that more than 16 million Americans (6%) abuse prescriptions like Xanax every year. Some 4.8 million Americans use Benzodiazepines every year, with Xanax as one of the best-known brand names.

5. Methamphetamine – 18,795 Total Deaths

Methamphetamine is the fifth most dangerous drug in the US, with 18,795 deaths caused by overdoses between 2013 and 2016. Meth is a part of the amphetamine family of stimulant drugs, it comes in several different forms including tablets, powder, or crystals.

Drugs causing the most US deaths

The Drugs with the Biggest Increase in Overdose Deaths

The data table below shows the total number of deaths caused by each stimulant in the three-year period, as well as their percent increase from 2013 to 2016.

Top 5 increase in overdose

 

1. Fentanyl – 855.45% increase

Within the three-year period, fentanyl saw the biggest increase in drug overdose deaths in the US (855.5%). As the second most dangerous drug behind heroin for its number of deaths, the alarming increase caused by synthetic opioid is equally concerning. In 2013, the death toll for fentanyl was at 1,919, fast forward to 2016, and this number increased to 18,335.

2. Cocaine – 112.75% increase

Cocaine saw the second highest increase in drug overdose deaths between 2013-2016 (112.8%). As the third most dangerous drug, causing 29,851 deaths by overdose between 2013 and 2016, the use of cocaine is on the rise, and it is unfortunately likely to take many more lives.

3. Methamphetamine – 111.71% increase

Methamphetamine had the third highest increase in overdose deaths over the years (111.71%). The death toll for meth was 3,194 in 2013 and 6,762 in 2016, a steady increase over the years.

Drugs with the most overdose increase

Methodology

While looking at overdose deaths in the US, we were limited to those drugs that had overdose death data available from the CDC. So, there are some dangerous drugs that may have caused overdose deaths that were not included in our study. However, these drugs were the substances that saw the most significant number of overdose deaths across the United States.

We started by using CDC resources to find drug overdose death rates. We were able to gather the number of 2020 deaths for each state. We then took all data from 2013 to 2020 to get a total number of deaths for the eight years and were able to calculate the increase from 2013-2020.

To gather the most dangerous drug’s data, we used another CDC resource, Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2011–2016  to find the top 15 drugs involved in drug overdose deaths in the United States from 2011–2016.

Is Januvia generic available yet?

Januvia is an expensive diabetes drug that helps to control blood sugar levels in patients with type 2 diabetes. There is currently no generic for Januvia available in the United States. It is not yet known when the first generic version of Januvia will become available.

Find out the earliest possible release date for generic Januvia and learn more about other options to save money on this medication until a Januvia generic substitute will become available in the future.

What is Januvia (sitagliptin phosphate)?

Januvia (sitagliptin) is a once-daily prescription diabetes pill that contains the drug sitagliptin, a type of dipeptidyl peptidase-4 (DPP-4) inhibitor. It is manufactured by Merck, also known as MSD.

This mediation helps lower blood sugar levels in adults with type 2 diabetes, in conjunction with diet and exercise. It is not approved for the treatment of type 2 diabetes mellitus.

Type 2 diabetes is a common medical condition that causes the level of sugar (glucose) in the blood to become too high which results in high blood sugar. Symptoms of high blood sugar (hyperglycemia) may include thirst, increased urination, drowsiness, confusion, rapid breathing, flushing, and fruity breath odor.

Januvia works by adjusting the levels of glucose and insulin that your body makes after eating. This medication is taken once per day and is used in conjunction with exercise and diet to improve blood sugar control.

This medication targets two primary problems in type 2 diabetes. It increases insulin production in the pancreas, and it decreases overproduction that occurs in the liver. When Januvia is used as an adjunct to diet and exercise, it has been shown to improve blood sugar control.

Januvia is also known to work by slowing the inactivation of incretin hormones (GLP-1 and GIP) that is released by your intestine throughout the day and in response to a meal. Incretin hormones are part of a complex system that helps to regulate your blood sugar.

It is available as a tablet in the dosage strengths 25 mg, 50mg, and 100 mg.

Januvia is considered a blockbuster diabetes drug for Merck, with estimated sales of over $3 billion in 2020, according to Merck’s 2021 financial results.

Merck also markets another prescription medication similar to Januvia called Janumet which includes the same active ingredient as Januvia, sitagliptin, with another popular drug called metformin. If your blood glucose is still high, your doctor may prescribe a second medication, such as metformin, to take with Januvia.

Sometimes, Januvia is also prescribed off-label for weight loss, although it is not FDA (Food and Drug Administration) approved for weight loss.

Are there cheaper alternatives to Januvia?

Drug nameApproved usesSide effectsGeneric available
Janumet, Janumet XR (sitagliptan/metformin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise)Nausea, diarrhea, vomiting, indigestion, gas, weakness, joint pain, headache, appetite loss, ovulation induction
Tradjenta (linagliptin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise)Low blood sugar, cough, cold diarrhea
Jardiance (empagliflozin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise); lower the risk of cardiovascular death in adults with type 2 diabetes and heart disease; lower the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure and reduced ejection fractionURI, UTI, high cholesterol, genital fungal infection, nausea, joint pain
Invokana (empagliflozin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise); lower the risk of major cardiovascular events in adults with type 2 diabetes and heart disease; lower the risk of end-stage kidney disease and other complications in adults with type 2 diabetes and diabetic nephropathyIncreased cholesterol, low blood sugar, genital fungal infection, high potassium levels, UTI, orthostatic hypotension, thirst, nausea, constipation, fatigue, risk of lower limb amputation
Onglyza (saxagliptin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise)UTI, URI, UTI, low blood sugar, headache, swelling, vomiting, kidney problems, stomach pain
Nesina (alogliptin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise)URI, low blood sugar, URI, kidney problems, headache
Ozempic (semaglutide)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise); lower risk of major cardiovascular events in adults with type 2 diabetes and heart diseaseNausea, diarrhea, low blood sugar, vomiting, constipation, stomach pain, burping, reflux, gas, diabetic retinopathy, indigestion, injection site reaction
Trulicity (dulaglutide)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise); lower the risk of major cardiovascular events in adults with type 2 diabetes and heart diseaseNausea, diarrhea, vomiting, constipation, low blood sugar, burping, stomach pain, gas, reflux, indigestion, injection site reaction, diabetic retinopathy
Farxiga (dapagliflozin)Improve blood sugar control in adults with type 2 diabetes (along with diet and exercise); lower the risk of hospitalization for heart failure in adults with heart disease and type 2 diabetes; lower the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure and reduced ejection fraction; lower the risk of kidney problems, hospitalization and death in adults with chronic kidney diseaseUTI, genital fungal infection, nausea, back pain, constipation, orthostatic hypotension, pain in the extremities,
Glucophage (metformin)Improve blood sugar control in adults and children (10+ years) with type 2 diabetes (along with diet and exercise)Nausea, diarrhea, vomiting, gas, indigestion, weakness, headache, appetite loss, ovulation induction
Victoza (liraglutide)Improve blood sugar control in adults and children (10+ years) with type 2 diabetes (along with diet and exercise); lower the risk of major cardiovascular events in adults with type 2 diabetes and heart diseaseNausea, diarrhea, vomiting, gas, indigestion, weakness, headache, appetite loss, ovulation induction

There are other several other alternatives to Januvia available that are approved for the treatment of type 2 diabetes. These medications have different strengths, dosages, and indications.

How much will generic Januvia cost once it’s available?

As there are no currently no generic substitutes available on the market, it is not yet known how much the generic version of Januvia will cost. However, generic drugs are typically significantly less expensive than brand-name medications, so those with type 2 diabetes can expect to pay a lot less money for the generic substitute of Januvia once it becomes available in the United States.

When will generic Januvia become available?

It is not yet known exactly when the generic Januvia will become available. The manufacturer of Januvia, Merck, disclosed in its 2020 annual report that it is extending the Januvia patent by covering “certain phosphate salt and polymorphic forms of sitagliptin.”

Merck has made significant efforts to protect its patents for Januvia (sitagliptin) and has been involved in litigation with several U.S. generic pharmaceutical companies, including Mylan NV, now Viatris, and Par Pharmaceuticals, that have intentions to market the generic version of Januvia. It is expected that the earliest possible date for a generic substitute to become available is sometime in 2027. which is the earliest time Januvia generic will become available for sale. It’s possible that the manufacturer may obtain authorization to extend the patent which commonly occurs, so it’s not possible to definitively estimate the release date for the first generic.

The Januvia generic name is sitagliptin and will be available under this name once it is approved for sale in the United States. A generic drug is chemically equivalent to the brand name drug and is considered to be safe and effective.

Januvia side effects

The most common side effects of Januvia are known to be upper respiratory tract infection, headache, stuffy or runny nose, and sore throat.

Other possible serious side effects of Januvia are:

  • Inflammation of the pancreas (pancreatitis)
  • Heart failure
  • Kidney problems
  • Low blood sugar (hypoglycemia)
  • Serious allergic reactions
  • Joint pain
  • Skin reaction

This medication may have other possible side effects, including diarrhea and stomach upset, and swelling of the legs or hands, when Januvia is used with metformin (Glucophage) and rosiglitazone (Avandia), two other oral diabetes drugs.

Januvia is not to be used for the treatment of type 1 diabetes or diabetic ketoacidosis (increased ketones in the blood or urine).

It is unknown whether Januvia passes into breast milk. Consult your healthcare provider before breastfeeding while taking this medication.

Speak with your prescribing doctor about all of the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Januvia. You should always seek the medical advice of a licensed healthcare professional for any questions or concerns relating to your medical condition or treatment.

How much does Januvia cost?

The estimated cost for Januvia is around $550 for 30 tablets without insurance. Price may vary by pharmacy.

Why is Januvia so expensive?

Januvia is so expensive because it is a brand-name medication. Brand-name drugs are always more expensive than generic drugs. The FDA-approved generic of Januvia (sitagliptin) will be much cheaper when it becomes available.

How do I save money on Januvia?

Fortunately, there are several options that may help you save money until there is a generic of Januviaa available on the market:

  1. Januvia Coupon – Merck provides a discount coupon to eligible, privately insured individuals who may pay as little as $5 per prescription. Maximum savings is $150 per prescription.* The coupon may be redeemed once every 30 days. to insured patients who are eligible. Make sure to check the offer on the website as the terms and eligibility requirements can change.
  2. Patient assistance programs – find out if you are eligible for enrollment into the Januvia patient assistance program.
  3. Ask your prescribing doctor for free samples of Januvia – many pharmaceutical companies provide healthcare providers with free samples to provide to their patients in order to help them get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative treatment options – there are several lower-cost generic alternatives for Januvia that you can discuss with your prescribing doctor.
  5. Shop around for the lowest price at multiple mail-order pharmacies – the price for Januvia may vary by pharmacy so you should always check pricing at multiple pharmacies to find the lowest possible price.
  6. Januvia coupons – find out if there is a Januvia manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Januvia.

Global Smoking Report

The biggest smoker countries and US states revealed

A huge portion of the world’s population are smokers, in fact, according to the World Health Organization, 22.3% of the global population used tobacco. The primary reason people smoke is to reduce stress, at the risk of addiction. This is because tobacco contains a chemical called nicotine, which creates a sense of relaxation when consumed.

Tobacco is one of the biggest causes of preventable deaths in the world, killing more than 8 million people worldwide, annually. It also increases the risk of a variety of health issues, such as an increased risk of a stroke, risk of multiple forms of cancer, as well as heart problems, such as heart disease.

The latter of which can be easily treatable with Entresto, a heart disease medication that we provide coupons for to help with the cost!

However, we at NiceRx, have researched which countries and US states have the highest smoking rates and most deaths caused by smoking. This will give you a good indication of which countries are plagued by smoking and its risks.

US states with the highest smoking rates

US states highest smoking

1. West Virginia

2022 Smoking Rate: 23.8%

West Virginia in the Southeastern region of the US is one of the smallest states, with a population of a little over 1.79 million, making it the twelfth least populous state. Despite that, it has the highest smoking rate in the states, at 23.8%.

2. Kentucky

2022 Smoking Rate: 23.6% 

Bordering West Virginia, is Kentucky which is also in the Southeast of the US, with a population of over 4.5 million people, as of 2020. It also has a smoking rate that rivals West Virginia, being just 0.2% lower.

3. Louisiana

2022 Smoking Rate: 21.9%

Louisiana is located in the deep South of the United States and is the 25th most populous state with 4.65 million people, despite being the 20th smallest state by area. As of 2022, the smoking rate for Louisiana is at 21.9%, making it the third highest in the whole United States.

4. Ohio

2022 Smoking Rate: 20.8%

In the Midwestern region of the United States lies the state of Ohio, the seventh most populous state with a little under 11.8 million people. Ohio’s smoking rate stands at 20.8% of the population for 2022, which is over 2.4 million smokers.

5. Mississippi

2022 Smoking Rate: 20.4%

And with the fifth highest smoking rate, we have Mississippi, another state located in the Southeastern region of the United States. It has a population of around 2.96 million people and is also the lowest-income state per capita. It also has a smoking rate of 20.4%, almost three times higher than Hawaii, the state with the lowest smoking rate.

US states highest smoking

US states with the highest smoking-related deaths

US states top 5 smoking death

1. West Virginia

Annual Deaths from Smoking per 100,000: 241

Having the highest smoking rate in the United States, it should come as no surprise that West Virginia ranks highest for most smoking-related deaths. Annually, this southeastern state records 241 deaths caused by smoking, per 100,000 people.

2. Kentucky

Annual Deaths from Smoking per 100,000: 197

Again, Kentucky follows as a somewhat close second, despite having more than double West Virginia’s population. High rates of smokers more often than not will lead to a higher rate of health issues, caused by tobacco use. This has even led to 197 deaths annual for the state, per 100,000 of the population.

3. Arkansas

Annual Deaths from Smoking per 100,000: 192 

A third state located in the south of the United States, Arkansas has a joint-sixth highest smoking rate in the whole of the US in 2022. Annually, the state has 192 deaths per 100,000 caused by smoking, just a few less than in Kentucky.

4. Oklahoma

Annual Deaths from Smoking per 100,000: 188

Oklahoma is also from the deep south of the United States and in fact, it shares its Eastern border with Arkansas. The state had a smoking rate of 18.9% in 2022, which puts it just outside the top ten. Despite this, the state still annually sees 188 smoking-related deaths per 100,000. However, it has been gradually tightening smoking laws, especially in relation to younger people. 

5. Mississippi

Annual Deaths from Smoking per 100,000: 183

To round out the top five, we have a fifth state that is located in the south of the United States, Mississippi. According to Tobacco Free Kids, the use of tobacco cost the state around $818 in government expenditures, per household. The use of tobacco also sees the state annually record 183 deaths per 100,000.

US states highest smoking deaths

Countries with the highest smoking rates

Top 5 countries smoking rates

1. Nauru

2022 Smoking Rate: 52.1% 

The Republic of Nauru is an island country in Oceania, and is the smallest republic in the world, with a population of around 10,000. Nauru has high rates of type 2 diabetes, heart and kidney disease, as well as a high rate of smokers. The latter can only serve to worsen the country’s current health issues. 

2. Kiribati

2022 Smoking Rate: 52% 

Another republic, located in Oceania, we have Kiribati, an archipelago country that has a population of over 119,000 as of 2020. The smoking rate, as of 2022, is more than half of the adult population which is astonishing. 

3. Tuvalu

2022 Smoking Rate: 48.7% 

Tuvalu is an island country, located in Oceania, specifically in the Polynesian subregion. In fact, its islands are located between Hawaii and Australia. As of the 2017 census, Tuvalu has a population of 10,507 and a smoking rate of 48.7%. The highest cause of death in the country is heart disease, followed by high blood pressure and with such high smoking rates, that can only make matters worse.

4. Myanmar

2022 Smoking Rate: 45.5%

The Republic of the Union of Myanmar is a country in Southeast Asia and is the largest country in this region of Asia with a population of 54 million people as of 2017. With a smoking rate of 45.5%, that is a huge number of smokers in the country.

5. Chile

2022 Smoking Rate: 44.7%

Next, we have the world’s most populous city, with more than 1.4 billion people, China, located in Eastern Asia. With that said, China’s smoking rate is at 44.7% as of 2022, considering the population, that’s an astronomical number of people.

Countries with highest smoking rates

Countries with the highest smoking-related deaths

Top 5 countries smoking deaths

1. Serbia

Number of Deaths from Smoking in 2019 per 100,000: 356

Serbia is situated in the Balkans, which is located in the Southeastern region of Europe, the country has a population of over 6.8 million people. It ranks within the top ten countries with the highest smoking rates, which serves as an explanation for its high smoking death rate. In 2019, Serbia had 356 deaths per 100,000 caused by smoking, higher than any other country.

2. Bulgaria

Number of Deaths from Smoking in 2019 per 100,000: 299

A second country located in the Balkans region of Europe, Bulgaria sits along the coast of the Black Sea. It is the sixteenth largest country in Europe by area and has a population of just under 6.9 million as of 2021. Bulgaria ranks exactly tenth among countries with the highest smoking rate and in 2019, it recorded 299 deaths per 100,000 due to smoking.

3. Montenegro

Number of Deaths from Smoking in 2019 per 100,000: 284

Montenegro is another European country located in the Balkans and shares its northeastern border with Serbia. It also shares maritime territory with Italy and is on the coast of the Adriatic Sea. Montenegro has a population of 620,170, making it the smallest Balkan country and it recorded 284 deaths caused by smoking per 100,000 people in 2019.

4. Bosnia and Herzegovina

Number of Deaths from Smoking in 2019 per 100,000: 267

Bosnia and Herzegovina, informally known as Bosnia, is a country situated at the crossroad between South and Southeast Europe, located in the Balkans. It has a slim coastline along the Adriatic Sea and shares borders with both Serbia and Montenegro. Bosnia fell just outside of the top ten countries for the highest global smoking rates, which surely contributed to its 267 deaths per 100,000 people, caused by smoking.

5. North Macedonia

Number of Deaths from Smoking in 2019 per 100,000: 257

Taking the fifth spot and ensuring the top five are all Balkan countries, is North Macedonia. This country shares borders with Serbia to the north and Bulgaria to the east, it is also completely landlocked. North Macedonia did not feature in the smoking rates ranking, however, surveys within the country show that the rate is very high along with second-hand smoke exposure. In 2019, the country recorded 257 deaths caused by smoking per 100,000 of the population.

Countries with highest smoking death rates

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Methodology

To get the smoking rates for both the US and Global ranking, we used the World Population Review Country rankingand the World Population Review US State ranking. We then ranked each country and state separately.

To get the global deaths caused by smoking we used Our World in Data, taking the 2019 total deaths for each country. And to get the US smoking-caused deaths, we used Tobacco Free Kids, which gives annual deaths for each state. We then took the population of each country and US state and calculated the deaths per 100,000 of the population. Again, we ranked each country and state in two separate rankings.

The 2022 Nursing Home Report

The US states with the best nursing homes

Old age can be a wonderful thing; a time to appreciate all the things that we have worked for in life and cherish time spent with loved ones.

However, with advanced age also often comes health issues that require prescription medications and physical deterioration. This means that many of us will need to rely on the care provided within a nursing home at some stage of life.

With this being such a vulnerable stage of life, we expect carers and nursing homes to take the utmost care of our elderly. However, according to the National Council on Aging, approximately 1-5 million seniors experience elder abuse every year, though the true figure may be much higher.

With this in mind, we wanted to find out which states have the best quality nursing homes and where neglect and abuse may be happening most often.

The states with the highest-rated nursing homes

Highest rated care homes

Using the U.S. News nursing home ratings, we were able to discover which states have the highest proportion of top-rated care facilities. By looking at the number of nursing homes given a 5/5 rating compared to the total number of nursing homes, we can reveal the states with the highest-rated nursing homes.

1. Hawaii

67.44% of nursing homes rated 5/5

Out of the 43 listed nursing homes in Hawaii, an impressive 29 have been awarded top marks with a rating of 5/5. Hawaii is known for its idyllic beaches and easygoing lifestyle, and it seems as though Hawaiians are just as concerned with providing the best quality of life for their elderly residents as well as everyone else.

2. Alaska

40.00% of nursing homes rated 5/5

The top two states couldn’t be much more different in terms of climate and landscape, but one thing they do have in common is the care they provide for their elderly residents. A total of eight of the 20 listed nursing homes have the highest rating available, showing just how much they value their elders.

3. Maine

32.26% of nursing homes rated 5/5

From the northwesternmost US state to the northeasternmost state, rounding out the top three is the state of Maine. With 30% of their 93 listed nursing homes being awarded a 5/5 rating, 32.26% of their facilities take the highest rating.

Highest rated state care homes

The states with the fewest highly-rated nursing homes

States with least highly rated care homes

At the other end of the scale, we have the nursing homes that fail to meet the highest standards. While these states may have nursing homes rated up to four out of five, they have the lowest proportion of homes with top marks.

1. Arkansas

0.00% of nursing homes rated 5/5 

Arkansas is the only state on our list that doesn’t have a single listed nursing home scoring top marks. While there are 224 homes to choose from, none achieved a 5/5 rating and only four achieved a 4/5 rating.

2. Oklahoma

0.67% of nursing homes rated 5/5 

With 298 listed nursing homes in Oklahoma, but just two rated as 5/5, this equates to less than 1% getting top marks. As with Arkansas nursing homes, only four are listed as achieving a 4/5 rating.

3. Alabama

1.75% of nursing homes rated 5/5

Taking third place with four top-rated nursing homes is the state of Alabama. With 228 listed nursing homes in the state, these top-rated nursing homes only account for 1.75% of facilities.

 

The states with the fewest searches for nursing home neglect lawyers

Fewest neglect searches

Looking at the number of Google searches made in each state for the phrases, ‘nursing home neglect lawyers’, ‘nursing home abuse lawyer’, ‘nursing home lawyers’, and ‘nursing home negligence lawyers’ we can see where residents are most likely to look for advice. We compared the number of these searches to the number of nursing homes to see how prevalent these issues may be.

1. Iowa

1.30 searches per nursing home 

Iowa saw the fewest searches related to nursing home lawyers from July 2021 to June 2022. While this doesn’t mean that the state is free of nursing home neglect and abuse, it suggests that it is at least not so prevalent as in other states where far more residents are searching for this type of advice. 

2. Kansas

1.33 searches per nursing home

With 560 searches in the past 12 months for nursing home neglect lawyers as well as other search terms, Kansas has just 1.33 searches per nursing home, suggesting that there are lower rates of neglect in Kansas facilities.

3. Minnesota

1.37 searches per nursing home

Minnesota has 364 listed nursing homes, and with 500 searches for nursing home neglect lawyers and other related terms, this equates to 1.37 searches per facility, showing that the issue seems to be less widespread in this state than in others.

States with fewest neglect searches

The states with the most searches for nursing home neglect lawyers

Most neglect lawyer searches

On the other side of things, we have the states where the most nursing home neglect lawyers searches happen. 

1. South Carolina

32.12 searches per nursing home

With 189 listed nursing homes and a total of 6,070 searches during the past 12 months, South Carolina takes the top spot for the highest number of searches per nursing home.

2. Arizona

23.31 searches per nursing home 

Arizona has fewer nursing homes than South Carolina, and with 3,380 searches for nursing home neglect lawyers, the state takes the second spot.

3. Florida

19.60 searches per nursing home

Florida is home to a whopping 705 nursing homes and with 13,820 searches for terms related to nursing home abuse and neglect lawyers, it’s clear that there are important improvements to be made.

States with most neglect searches

The states where searches for nursing home neglect lawyers are dropping

Nurse home neglect searches dropping

While high volumes of searches for nursing home neglect lawyers are a worrying trend, there are some states where searches are decreasing, suggesting that the issue is becoming less prevalent in these states. 

1. Idaho

52.2% YoY decrease in searches

Idaho has seen the largest decrease in searches, going from 670 searches to 320 searches comparing the past 12 months to the previous period. This equates to a decrease of 52.2%. 

2. Kentucky

46.0% YoY decrease in searches 

While 1,690 searches for nursing home lawyers and related phrases may seem like a lot, this has actually decreased by 46% as the state saw 3,130 searches in the previous 12-month period. 

3. Georgia

31.6% YoY decrease in searches

The state of Georgia has also seen a decrease in searches for nursing home neglect lawyers, going from 8,470 searches to 5,790 searches year on year.

States where neglect is dropping

The states where searches for nursing home neglect lawyers are rising

Care home neglect is rising

Unfortunately, not every state is seeing searches for nursing home neglect lawyers drop. In fact, in these states, searches are on the rise, suggesting that it is becoming increasingly problematic.

1. Arizona

271.4% YoY increase in searches 

Taking the top spot is Arizona where searches jumped from 910 to 3,380 in the past 12 months, making an increase of 271.4%. 

2. Maryland

196.7% YoY increase in searches

In the state of Maryland, searches increased by 196.7% over the past 12 months when compared to the previous period.

3. Illinois

183.6% YoY increase in searches 

Lastly, Illinois completes the top three with a 183.6% increase in searches for nursing home neglect lawyers and related terms, jumping from 4,260 searches to 12,080 searches.

States where neglect search is rising

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Methodology: 

Looking at all 50 states, we searched state by state for the number of nursing homes according to the US News Best Nursing Homes Ratings, also taking the number of nursing homes rated five out of five.

We also looked at the number of Google searches for the terms ‘nursing home neglect lawyers’, ‘nursing home abuse lawyer’, nursing home lawyers’ and ‘nursing home negligence lawyers’, comparing the July 2020 – June 2021 period to the July 2021 – June 2022 period, taking the totals for each and comparing the search increase or decrease.

US Medical Debt Report

How does medical debt vary across the country?

Receiving medical treatment can be an unpleasant experience at the best of times, but the added pressure of sky-high medical bills means many patients are discharged with huge sums of debt. These high costs are present across the US health industry, making access to medicine, consultations, and treatment a costly financial burden that many households simply cannot afford.

Thankfully, there are ways of making healthcare more affordable on a day-to-day basis. Ensuring you have adequate insurance coverage is incredibly important for making sure you have access to medical treatment in an emergency, though many plans do not cover medication and other costs that can add up over time.

Luckily, you can now get affordable medications online by signing up for a service such as NiceRx, where you will receive your monthly prescriptions for a fraction of the regular retail price. This service is available for accessing a wide range of medications directly from pharmaceutical companies, including popular brand names such as Vyvanse, which is commonly used to treat ADHD.

Despite there being several ways to reduce the burden of medical expenses, huge numbers of Americans still find themselves with substantial medical debt. With this in mind, we at NiceRx wanted to find out who in the US has the most medical debt. We’ll reveal which demographics in the country bear the largest financial burden for medical expenses, as well as looking at the difference in debt levels from state to state.

Medical debt by age and generation

Medical debt by age

Age group where medical debt is most prevalent:

Age group: 45 to 54 years

Percent with medical debt: 20.70%

The age group where the most people have some level of medical debt are those between 45 and 54 years of age, with 20.70% of people having medical debt. This means more than 1 in 5 Americans in this age range are dealing with medical debt.

The age group with the highest average medical debt:

Age group: 75 and over

Average value of medical debt: $17,510

The age group with the highest level of medical debt is also the oldest, with people aged 75 and over having an average medical debt of $17,510. While this could make sense as older people generally have more health conditions, and they’ll have had longer to accumulate the debt, they also have to balance the cost of this debt with their retirement funds, which can be tricky to do.

Medical age by generation

The generation where medical debt is most prevalent:

Generation: Generation X

Percent with medical debt: 16.30%

The generation where medical debt is most common is Generation X, with 16.30% of people owing money for medical expenses. This means that people born between 1965 and 1980 are the most likely to hold medical debt.

The generation with the highest average medical debt:

Generation: Generation Z

Average value of medical debt: $19,890

The generation with the highest average medical debt is Generation Z, where the average amount owed is $19,890. This means that the youngest generation is also bearing the largest financial burden from medical debt. This could be a problem for many people as younger workers tend to earn less than their older and more senior colleagues.

Medical debt by household income

Medical debt by household income

Here we can see the levels of medical debt held by different earning brackets. The data has been split into quintiles, each representing 20% of workers, with the lowest earners in the lowest quintile.

The income bracket where medical debt is most common is the third quintile. This means that those earning mid-range salaries are most likely to have medical debt, which is the case for 20.20% of people in this bracket.

The earners with the highest average value on medical debt are in the top quintile, with average debts of $18,950, meaning the highest earners also owe the most for medical expenses.

Medical debt by ethnicity

Medical debt by ethnicity

26.90% of black people in the US have medical debt, making them the ethnic group where medical debt is most common. Conversely, Asian people have the lowest prevalence of medical debt at just 8.90%.

However, the high prevalence of medical debt that black people experience does not translate into high average debt, as non-Hispanic white people have the highest average medical debt at $14,540.

Medical debt by disability status

Medical debt by disability status

There is also a marked difference in levels of medical debt between those with disabilities and those without. Households with at least one disability are almost twice as likely to have medical debts than those without, with prevalence rates of 24.20% compared to 12.80%.

The average value of medical debt is also much higher for households with a disability, being almost three times higher than those without a disability at $18,100 compared to $6,796.

Medical debt by insurance coverage

Medical debt by insurance coverage

We can also compare the difference in medical debt between people with full health insurance, and those with no or partial coverage. Here we can see that those without full health insurance are much more likely to have medical debt at 27.90% compared to 14.60%. They also have much higher medical debt, owing $18.150 on average compared to $10,570.

Comparing levels of medical debt between states

Levels of medical debt also vary depending on where you are across the country. Some states have much higher rates of medical debt, while others owe much more on average. Here we will explore how states compare in terms of total medical debt, average medical debt, and prevalence of medical debt.

Total statewide levels of medical debt

Total statewide levels of medical debt

1. Texas

Total Medical Debt: $14,608 million

Texas has the highest amount of medical debt in the country at $14,608 million. This huge sum is far higher than second-place Florida, where the total amount of medical debt stands at $8,213.

RankStateTotal medical debt
50Vermont$42 M
49North Dakota$61 M
48Rhode Island$72 M
47South Dakota$79 M
46Hawaii$126 M
45New Hampshire$133 M
44Minnesota$148 M
43Montana$279 M
42Massachusetts$296 M
41Alaska$318 M

50. Vermont

Total Medical Debt: $42 million

Vermont has the lowest level of medical debt of any state at $42 million. This is followed by North Dakota with $61 million and Rhode Island with $72 million. While it may not be the only factor at play, all three of these states have relatively low populations, which will have an impact on the overall amount of medical debt.

The prevalence of medical debt by state

The prevalence of medical debt by state

1. West Virginia

Percent of people with medical debt: 24.99%

The state where medical debt is the most common is West Virginia where 24.99%, approximately one-quarter, of people have medical debt. This is just a little more than second-place South Carolina, where 22.87% of people have medical debt, so there’s not a huge amount in it.

50. Minnesota

Percent of people with medical debt: 2.25%

Minnesota has the lowest prevalence of medical debt, with only 2.25% of people owing money for medical expenses. This impressively low rate is followed by South Dakota at 4.43% and Massachusetts at 4.72%.

Average medical debt by state

Average medical debt by state

1. Wyoming

Average medical debt: $6,516

Wyoming has the highest average medical debt of any state at $6,516 per person. This is far higher than any other state, with second place Alaska having an average medical debt of $3,752.

50. Massachusetts

Average medical debt: $975

Massachusetts has the lowest average medical debt of any state at just $975, also making it the only state with an average figure below $1,000. Massachusetts is followed by Maryland in second place with an average medical debt of $1,160, while New York state took third place with an average medical debt of $1,186.

Methodology

We wanted to explore the medical debt landscape in the US to see which states and demographics owe the most for medical expenses. To compare different demographics, we used data from the United States Census Bureau, while for state comparisons we used data from the Consumer Protection Bureau.

When will Entresto generic be available?

Entresto is a popular brand-name drug used to treat congestive heart failure. It is manufactured and marketed by a Swiss pharmaceutical company, Novartis Pharmaceuticals, with an estimated $2.5 billion in annual sales in 2020 and expected to increase since granted extended indication approval by the FDA.

In 2018, heart failure was mentioned on 379,800 death certificates. Around 6.2 million Americans have heart failure.

Unfortunately for those who are diagnosed with heart failure, there is currently no generic version of Entresto available on the market in the United States, and the manufacturer was recently granted extended indication approval by the FDA which will further delay the release of the first generic alternative medication. Fortunately, there are several options for you to save money on heart failure medication until generic Entresto is available.

What is Entresto (sacubitril/valsartan)?

Entresto (sacubitril/valsartan) is a popular brand-name prescription medication used to treat adults with long-lasting (chronic) heart failure, also known as congestive heart failure, and helps to reduce the risk of cardiovascular death and hospitalization. It is a combination of two medications, sacubitril and valsartan, and is available as a tablet in doses 24/26mg, 49/51mg, and 97/103mg.

Sacubitril belongs to a class of drugs called neprilysin inhibitors and valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). These medications work by relaxing blood vessels so that blood is able to flow more easily, making it easier for the heart to pump blood to the body.

The typical starting dose for this medication is 24/26mg.  The valsartan in this medication is more bioavailable than the valsartan in other marketed tablet formulations – 26mg, 51mg, and 103mg of valsartan in this medication are equivalent to 40 mg, 80 mg, and 160 mg of valsartan in other marketed tablet formulations.

Heart failure occurs when your heart muscle doesn’t pump blood as well as it should. This can cause symptoms such as shortness of breath, fatigue, and swelling in your legs and feet. Entresto works better when the heart cannot pump a normal amount of blood to the body.

Entresto belongs to a class of drugs called angiotensin receptor-neprilysin inhibitors (ARNIs). A class of drugs refers to medications that work similarly. They have a similar chemical structure and are often used to treat similar conditions.

Lab and/or medical tests (such as tests for kidney function and potassium levels) should be done while you are taking Entresto.

It was first approved by the FDA in 2015 for the treatment of heart failure in people with reduced ejection fraction (HFrEF), which is when the heart is so weak that it can only pump 40% or less of the blood in the left ventricle, leading to symptoms like breathlessness.

In clinical trials, Entresto demonstrated to help people with HFrEF stay alive and out of the hospital longer. In PARADIGM-HF, the largest heart failure trial ever conducted, ENTRESTO was also proven to be superior to enalapril.

Entresto was recently granted a patent extension by the FDA until 2024 for extended indication approval for heart failure patients with preserved ejection fraction, which means their hearts can pump out more blood but still less than normal.

What is a generic drug?

A generic drug is a medication created to be the same as an existing approved brand-name drug in dosage, safety, strength, route of administration, quality, and performance characteristics.

Generic drugs are needed for enabling affordable access to essential medications such as Entresto. When Entresto becomes available in generic form, more people will be able to afford the medication.

Patent protection provides an incentive for drug companies to invest in the research and development of new drugs. The patent protection period typically lasts for around 20 years and provides the pharmaceutical company with the exclusivity to sell the medication without any competition. Once a drug’s patent expires, other companies can develop and sell generic versions of the medication.

Generic drugs use the same active ingredients as their brand-name counterparts and FDA requires that they are just as safe and effective.

RELATED: Generic vs brand name drugs

How much will the generic cost?

The price of generic Entresto has not yet been announced. However, the generic will likely be much cheaper than the brand-name drug once it becomes available.

Get your Entresto medication for only $49 per month

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When will generic Entresto become available?

Unfortunately, there is no specific Entresto generic release date that is known at this time. The patent for Entresto was recently extended as a result of an extended indication approval granted by the FDA.

The manufacturer Novartis has been involved in litigation with several generic pharmaceutical companies (including Alkem, Aurobindo, Dr. Reddy’s, Hetero, Laurus, Macleods and Torrent) that would like to start marketing a generic version of Entresto in the United States.

What is an alternative to Entresto?

While there are no generic Entresto alternatives available on the market yet, you can speak to your doctor about the possibility of using other lower-cost medications that are indicated for heart failure.

These are the most prescribed or over-the-counter congestive heart failure medications approved by the Food and Drug Administration (FDA). All of these medications, with the exception of Entresto, have a generic alternative available that may result in significant savings.

Best medications for congestive heart failure

Drug nameDrug classAdministration routeStandard dosageCommon side effects
Entresto (sacubritril/valsartan)Angiotensin receptor-neprilysin inh. (ARNi)Oral49mg/51mg to 97mg/103mg twice daily.Low blood pressure, high blood potassium, cough
BiDil (isosorbide dinitrate/hydralazine HCL)Nitrate/vasodilatorOral20mg/37.5mg to 40mg/75mg every 8 hours.Flushing, low blood pressure, dizziness, headache
Atacand (candesartan)ARBOral16mg to 32mg once daily.Headache, Upper respiratory tract infection, back pain, dizziness
Diovan (valsartan)ARBOral80mg to 320mg once daily.High blood potassium, dizziness, fatigue, low blood pressure
Altace (ramipril)ACE inhibitorOral2.5mg to 20mg once daily or divided every 12 hours.Cough, low blood pressure, headache, chest pain
Vasotec (enalapril)ACE inhibitorOral5mg to 40mg per day divided every 12 hours.Dizziness, low blood pressure, headache, cough
Coreg (carvedilol)Beta-blockerOral3.125mg to 25mg twice daily.Dizziness, fatigue, low blood pressure, weight gain
Lopressor (metoprolol)Beta-blockerOral100mg to 450mg per day divided every 12 hours.Dizziness, headache, fatigue, slow heart rate
Toprol XL (metoprolol)Beta-blockerOral25mg to 400mg once daily.Dizziness, headache, fatigue, slow heart rate
Inspra (eplerenone)Aldosterone antagonistOral50mg to 100mg per day. May be divided every 12 hours.High blood potassium, dizziness, fatigue, diarrhea
Aldactone (spironolactone)Aldosterone antagonistOral25mg to 50mg once daily.High blood potassium, fatigue, dizziness
Lasix (furosemide)Loop diureticOral20mg to 80mg once daily but may increase to a max of 600mg per day.Elevated blood uric acid, low blood potassium, dizziness
Demadex (torsemide)Loop diureticOral10mg to 20mg once daily. May double dose up to a max of 200mg per day.Excess urination, headache, electrolyte imbalance, dizziness
Zaroxolyn (metolazone)Thiazide diureticOral2.5mg to 20mg once daily.Dizziness, drowsiness, depressed mood, nausea, joint pain
Lanoxin (digoxin)Cardiac glycosideOral0.125mg to 0.25mg once daily.Dizziness, diarrhea, confusion, headache, vomiting
Verquvo (vericiguat)Soluble guanylate cyclase stimulatorOral2.5mg to 10mg once daily.Low blood pressure, anemia

RELATED: Entresto alternatives: which other heart medications can I take?

How do you take Entresto?

Entresto is taken orally in tablet form, usually in combination with other heart failure medications, in place of an ACE inhibitor (such as enalapril or lisinopril) or other ARB.

To reduce the risk of side effects, your prescribing doctor may start you on the low dose of 49/51mg, taken twice daily. Your doctor may gradually increase your dose based on how you respond to the medication and if you experience any side effects.

If you have been prescribed Entresto and are currently taking an ACE inhibitor, you should stop taking your ACE inhibitor, wait for 36 hours, and then start taking Entresto as prescribed.

You should always take Entresto as prescribed by your doctor.

Who can take Entresto?

Do not take this medication if you:

  • are allergic to any of its ingredients
  • have had an allergic reaction including swelling of your face, lips, tongue, throat (angioedema) or trouble breathing while taking a type of medicine known as an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB)
  • are taking an ACE inhibitor medication – you should not take this medication for at least 36 hours before or after you take an ACE inhibitor medicine.
  • have diabetes and take a medication that contains aliskiren

Tell your healthcare provider all of the medications you are taking, including prescription drugs, over-the-counter products, herbal supplements, and vitamins. Your doctor will evaluate if there are any possible drug interactions when combining anything else you are taking with Entresto. Tell your healthcare provider if you are taking potassium supplements or a salt substitute, lithium, nonsteroidal anti-inflammatory drugs (NSAIDs), or any other medicines that are used for high blood pressure or heart problems such as an ACE inhibitor, ARB, or aliskiren.

It is not known if Entresto passes into breast milk. Speak with your doctor before breastfeeding.

Side effects of Entresto

The most common side effects of Entresto are:

  • low blood pressure
  • high potassium
  • cough
  • dizziness
  • kidney problems

Entresto may also cause more serious side effects such as:

  • swelling of the face,  tongue, lips, and throat (angioedema) that could cause trouble breathing and possible death
  • Black patients or those who have a history of angioedema and take this medication could have a higher risk of having angioedema
  • low blood pressure (hypotension)
  • kidney problems
  • an increased amount of potassium in your blood (hyperkalemia)

This is not a full list of all of the possible side effects of Entresto. You should always seek the medical advice of a licensed healthcare professional for any questions or concerns relating to your medical condition or treatment.

How much does Entresto cost?

In 2022, Novartis provides an estimated list price of $624 per month for those without insurance.

The manufacturer states on its website that Entresto has preferred coverage for more than 99% of Medicare and on average, 80% of people with Medicare Part D pay less than $50 a month out of pocket for their Entresto prescription, and over 50% of people with Medicare Part D pay $10 or less for their Entresto prescription every month.

Novartis also provides a savings card for those with commercial or private insurance that includes a copay offer to pay as little as $10 for a 30-day, 60-day or 90-day supply of Entresto.

It is also recommended to check the manufacturer’s website for the latest terms and requirements.

RELATED: How much does Entresto cost with Medicare?

Why is Entresto so expensive?

Entresto is so expensive because it is a brand-name medication. Brand-name drugs are always more expensive than generic drugs. In contrast, the FDA-approved generic of Entresto will be much cheaper once it becomes available.

How do I save money on Entresto?

Fortunately, there are several options that may help you save money until there is a generic version of Entresto available on the market:

  1. Entresto savings card – the manufacturer offers a discount savings card to insured patients who are eligible. Make sure to check the offer on the website as the terms and eligibility requirements can change.
  2. Patient assistance programs – find out if you are eligible for enrollment into the Entresto patient assistance program.
  3. Ask your prescribing doctor for free samples of Entresto – many pharmaceutical companies provide healthcare providers with free samples to provide to their patients in order to help them get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative treatment options – there are several lower-cost generic alternatives for Entresto such as lisinopril, carvedilol, valsartan and enalapril that you can discuss with your prescribing doctor.
  5. Shop around for the lowest price at multiple mail-order pharmacies – the price for Entresto may vary by pharmacy so you should always check pricing at multiple pharmacies to find the lowest possible price.
  6. Entresto coupons – find out if there is an Entresto manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Entresto.

Victoza for weight loss: does it work?

The main use of Victoza is to decrease blood sugar along with diet and exercise in adults and children who are 10 years of age and up with type 2 diabetes mellitus. Victoza also reduces the risk of major cardiovascular events associated with type 2 diabetes mellitus with known heart disease (ie heart attack, stroke, or death).

Victoza is a once-daily, non-insulin medication that is taken to lower A1C. Taking Victoza helps the pancreas produce additional insulin by helping important cells called beta cells to help control blood glucose levels by making and releasing insulin.

Approximately 70% of American adults are obese or overweight. Obesity and overweight are serious health conditions associated with some leading causes of death, including heart disease, stroke, and diabetes. It is also associated with an increased risk of certain types of cancer. Losing 5% to 10% of body weight through diet and exercise has been associated with a reduced risk of cardiovascular disease in adults with obesity or overweight.

What is Victoza (liraglutide)?

Victoza works similarly to glucagon-like peptide-1 (GLP-1), a hormone naturally produced and released by your body after eating. This helps to control your blood sugar level after meals by slowing down the process of food leaving your stomach. Victoza prevents the liver from producing too much glucose, and when blood sugar levels are high, it prompts the pancreas to create more insulin. Diabetes affects your metabolism and causes high blood sugar due to problems associated with using or making insulin in your body.

Victoza is not insulin so it can be taken in combination with long-acting insulin as separate subcutaneous injections. Both drugs can be injected in the same body area (ie. stomach area), however, they should not be injected close together.

Victoza can be taken at any time of the day, once a day, and does not need to be taken at meal time. It should be injected at the same time every day, so it’s best to get into a daily routine. Victoza should be injected under the skin in your upper arm, abdominal area (stomach), or thigh (upper leg), as instructed by your doctor. Victoza should not be injected into a vein or muscle.

Does Victoza cause weight loss?

Victoza is not meant to be used specifically for weight loss, however, due to the way this drug works, it may assist adults to lose weight. In a clinical trial studying adults with type 2 diabetes mellitus, Victoza was shown to lead to weight loss when combined with metformin. In addition, it is recommended that overweight individuals that are diagnosed with type 2 diabetes should prioritize weight loss as part of their ongoing management of diabetes. The American Diabetes Association recommends weight loss as an important goal for people with type 2 diabetes who are overweight.

One publication examined 5 randomized clinical trials of liraglutide for weight management. When combined with changes in diet and physical activity, taking liraglutide led to a weight loss of 4-6 kg.

In one study, people with obesity and PCOS successfully lost more weight when they took metformin and Victoza, compared to taking either drug by itself. Metformin is a prescription drug that is commonly prescribed for diabetes and PCOS.

Saxenda is another prescription drug that contains the same active ingredient as Victoza and is FDA-approved to be used for weight loss.

How does Victoza cause weight loss?

Victoza works similarly to glucagon-like peptide-1 (GLP-1) which is a hormone that your body naturally produces and releases after eating. This can help with weight loss as it controls your blood sugar level after eating by slowing down the process of gastric emptying. Victoza prevents the liver from producing too much glucose, and when blood sugar levels are increased, it prompts the pancreas to create more insulin.

How much weight can you lose with Victoza?

In a randomized study of 30 obese women with PCOS, subjects were randomized either to a combination of metformin and liraglutide (1.2 mg) or liraglutide (3 mg) alone for 12 weeks. Significant weight loss was found in both groups: up to 6.1 kg (13.5 pounds) was lost in the combination group (metformin and liraglutide) and up to 10 kg (22 pounds) was lost in the liraglutide alone group.

Who can take Victoza for weight loss?

Adults and children over the age of 10 can take Victoza to help manage their type 2 diabetes.

Victoza should not be taken if you:

  • are less than 10 years old
  • are already taking another medication that contains liraglutide.
  • diagnosed with type 1 diabetes mellitus
  • if you have an endocrine condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or if you or a family member have ever had MTC.
  • allergic to any of the ingredients in Victoza including liraglutide or have ever had an allergic reaction to any of the ingredients in Victoza
  • are planning to become pregnant or are already pregnant

Before beginning to take Victoza, discuss with your doctor or healthcare professional if you have any medical conditions, including if you:

  • are taking other diabetes medications
  • have severe abdominal problems, such as digesting problems, or gastroparesis (slow emptying of your stomach)
  • if you have had any health issues with your liver, kidneys, or pancreas
  • plan to or are currently pregnant
  • plan to or are currently breastfeeding

Victoza alternatives for weight loss

Wegovy

Wegovy is a weight loss drug manufactured by Novo Nordisk and the active ingredient is semaglutide. Wegovy is a once-weekly injection and is used in combination with a healthy diet and increased physical activity to manage weight in adults with one weight-related comorbidity (ie. hypertension, dyslipidemia, or type 2 diabetes mellitus) with initial body mass index (BMI) ≥30 kg/m2 (obesity) or ≥27 kg/m2 (overweight).

The difference between Wegovy and Victoza is the active ingredient, dose, and frequency. The dosing for Victoza is up to 18 mg/3 mL once per day and the dosing for Wegovy is up to 2.4 mg once per week. The higher doses of Wegovy are associated with greater weight loss. In the specific population that was studied for Wegovy, the average person lost 35 pounds after 68 weeks (approximately 16 months). In contrast, in the specific population studied for Victoza, the subjects lost up to 20 pounds.

Saxenda

Saxenda is an FDA-approved prescription injectable weight loss drug with the active ingredient liraglutide and is manufactured by Novo Nordisk. It helps people to lose weight and keep the weight off.

Rybelsus

Rybelsus is a brand-name medication that is manufactured by Novo Nordisk. Rybelsus is available in tablet form and is taken by mouth once daily, with or without food. Rybelsus isn’t prescribed for weight loss, but weight loss is a possible side effect due to blood sugar management and the recommended lifestyle changes.

Trulicity

Trulicity is a brand-name drug manufactured by Eli Lilly. It is an FDA (U.S. Food and Drug Administration) approved prescription drug for adults who have type 2 diabetes. It is not approved for weight loss. Reduced appetite and thus weight loss is a possible side effect of Trulicity.

RELATED: Trulicity vs Victoza

Ozempic

Ozempic is an FDA-approved prescription drug made by Novo Nordisk. It is used for the treatment of type 2 diabetes to prevent your blood sugar from rising after eating. Ozempic is also used to lower the risk of a heart attack in type 2 diabetics. It causes your pancreas to secrete more insulin, helping to lower your blood sugar and reduce your risk of major cardiovascular events, like heart attacks and strokes, if you have cardiovascular disease (heart disease). Ozempic is used alongside dietary and lifestyle changes.

RELATED: Ozempic vs Victoza

You can also consider Compounded Semaglutide and Compounded Tirzepatide for weight loss.

Other diabetic medications that may cause weight loss

There are other diabetic medications that have been shown to cause weight loss. Weight loss can also be a desirable effect for people who are diagnosed with type 2 diabetes. Diabetic medications that may cause weight loss include:

Victoza side effects

The most common side effects of Victoza in adults are:

The following are less common serious side effects of Victoza:

  • pancreatitis (inflammation of the pancreas)
  • low blood sugar (hypoglycemia)
  • higher risk of thyroid tumors
  • severe low blood sugar levels (hypoglycemia)
  • kidney failure (or kidney problems)
  • gallbladder issues
  • severe allergic reactions

Since thyroid tumors (including cancer) are one of the less common but serious side effects of taking Victoza, it is important to be extra vigilant to identify the signs of this cancer. If you notice any hoarseness, swelling, a lump in your neck, difficulty or trouble swallowing, or experience shortness of breath, you should contact your healthcare provider immediately to obtain medical advice as these are symptoms of thyroid cancer.

Seek emergency medical attention, or call your healthcare professional if you experience an allergic reaction or experience any of these severe side effects when taking Victoza.

Victoza drug interactions

Caution should be exercised when taking Victoza with oral medications since Victoza can affect the absorption of these medications. Victoza can be used with some other diabetes treatments but should be discussed with your doctor. Also, it is recommended to consult with your doctor about all possible drug interactions with over-the-counter drugs, other prescription medications, herbal products, or supplements, and other medications you are taking to treat diabetes, including insulin or sulfonylureas.

Victoza may cause low blood sugar (hypoglycemia) or high blood pressure (hyperglycemia). If you are taking any blood pressure medications with Victoza, your healthcare provider will likely monitor your blood pressure to make sure that your body is absorbing that medication.

Is Victoza used for cardiovascular disease?

Cardiovascular disease includes conditions that affect the heart and blood vessels.

Victoza is FDA-approved to be prescribed to adults and children over 10 years old with type 2 diabetes mellitus to decrease blood sugar along with diet and exercise. Victoza also reduces the risk of major cardiovascular events associated with type 2 diabetes mellitus with known heart disease (ie heart attack, stroke, or death).

If you have type 2 diabetes and are at risk for cardiovascular disease, your doctor may prescribe Ozempic to help reduce your risk of cardiovascular death.

Does Victoza reduce blood pressure?

Victoza is not FDA-approved to treat high blood pressure. Type 2 diabetes increases your risk of cardiovascular events and disease including high blood pressure (hypertension). Controlling your diabetes through medication and in combination with healthy eating and exercise does help to reduce that risk.

When should I take Victoza?

Victoza can be taken at any time of the day, once a day, and does not need to be taken at meal time. It should be injected at the same time every day, so it’s best to get into a daily routine. Victoza should be injected under the skin in your upper arm, abdominal area (stomach), or thigh (upper leg), as instructed by your doctor. Victoza should not be injected into a vein or muscle.

Victoza is available in the dosage form 18MG/3ML Solution Pen-injector. The manufacturer recommends starting with a dosage of 0.6 mg for the first week and increasing the dosage to 1.2 mg daily for week 2, and if needed further increasing the dosage up to a maximum of 1.8 mg daily. You should discuss the correct dosage for you with your doctor.

Bottom line

  • Victoza is not indicated for weight loss, but it may result in moderate weight loss for people who take this medication alone or in combination with other medications such as metformin.
  • Although not approved for weight loss, Victoza has been shown to result in weight loss for certain populations.
  • In addition to possible weight loss, Victoza can positively affect your cardiovascular health and reduce the risk of death from heart-related disease.
  • You can speak with your doctor to find out if Victoza can be prescribed off-label for weight management.

Trulicity for weight loss: does it work?

Trulicity is a prescription drug used for the treatment of type 2 diabetes. As a glucagon-like peptide-1 (GLP-1) receptor agonist, Trulicity works by stimulating the body’s natural production of insulin, inhibiting the release of glucagon and slowing digestion. In clinical trials, Trulicity has been shown to help people with type 2 diabetes lose weight and improve their glycemic control.

It is estimated that around 70% of adults in the United States are obese or overweight. Obesity and overweight are serious health conditions that are associated with some of the leading causes of death, including heart disease, stroke, and diabetes, as well as an increased risk of certain types of cancer. Losing 5% to 10% of body weight through diet and exercise has been associated with a reduced risk of cardiovascular disease in adults who are obese or overweight.

What is Trulicity (dulaglutide)?

Trulicity is an FDA-approved brand-name medication that is used as an adjunct to exercise and diet to improve glycemic control in adults with type 2 diabetes mellitus. It is proven to help lower A1C and is also used to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus who have established cardiovascular disease or multiple cardiovascular risk factors. Although not indicated for weight loss, Trulicity is known to cause weight loss as a side effect of taking the medication.

Trulicity is part of a class of drugs called GLP-1 receptor agonists. The active ingredient in Trulicity is dulaglutide and this medication is manufactured by Eli Lilly. These drugs work by increasing insulin release and suppressing glucagon (a hormone that raises blood sugar levels) in response to meals. As a result, Trulicity can help lower blood glucose levels after meals.

Trulicity is available in prefilled pens in the following doses:

  • 0.75mg pen
  • 1.5mg pen
  • 3.0mg pen
  • 4.5mg pen

The recommended initial dose of Trulicity is 0.75mg injection subcutaneously (under the skin, in the abdomen, thigh or upper arm) once weekly and is increased to 1.5mg once weekly for additional glycemic control. If additional glycemic control is needed, the dose is increased to 3mg once weekly after at least 4 weeks on the 1.5mg dose. If after 4 weeks on the 3mg dose, additional glycemic control is needed, the dose of Trulicity is increased to 4.5mg once weekly.

This medication should be taken once weekly, any time of the day, and can be taken with or without food.

Is Trulicity prescribed for weight loss?

No, Trulicity is not specifically prescribed for weight loss. However, as a side effect of taking the medication, many people do experience weight loss.

If you are interested in learning more about using Trulicity for weight loss, speak with your healthcare provider about the potential risks and benefits of using Trulicity for weight loss. Trulicity may be prescribed off-label for weight loss if your prescribing doctor determines that it is safe and medically appropriate.

Does Trulicity cause weight loss?

Clinical studies have demonstrated that Trulicity has been successful at helping people lose weight, despite the fact that Trulicity is not indicated for weight loss. Trulicity should be used in combination with diet and exercise. However, not all people in the study lost weight.

If you are considering using Trulicity for weight loss, you should get medical advice from your healthcare professional regarding the potential risks and benefits of using Trulicity for weight loss.

How does Trulicity cause weight loss?

Trulicity acts like GLP-1 and binds to the GLP-1 receptors. It stimulates insulin release from the pancreas and reduces the amount of glucose that the liver produces, which makes you feel full by slowing gastric emptying.

How much weight can you lose with Trulicity?

The manufacturer of Trulicity, Lilly, reported on a 36-week clinical study of people with a BMI (body mass index) of greater than or less than 33.2 or higher. Doses of Trulicity 1.5mg, 3.0mg, and 4.5mg were evaluated in the study to report on the varying results of Trulicity dosages for weight loss. People with higher BMI that were taking higher doses of Trulicity had the most weight loss as measured in pounds lost from baseline. The average weight loss from the highest dose of Trulicity (4.5 mg) was 10.1 pounds. Trulicity 3mg was found to not be statistically significant vs Trulicity 1.5mg on weight change.

As well, the AWARD-11 clinical trial showed that weight loss had occurred most frequently in people with the highest initial BMI who were on the highest doses of Trulicity.

Trulicity dosage for weight loss

DosageAverage weight loss
1.5 mg6.6 lbs
3 mg8.4 lbs
4.5 mg10.1 lbs

Source: Trulicity and weight loss

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Who can take Trulicity for weight loss?

Trulicity is not FDA-approved for weight loss. However, there are other GLP-1 receptor antagonists that are FDA-approved for weight loss. Saxenda (liraglutide) and Wegovy (semaglutide) are indicated for weight loss treatment.

Trulicity has been prescribed off-label for weight loss and studies have shown that Trulicity can cause weight loss as a positive side effect.

This medication is only FDA-approved to be used in people with Type 2 diabetes mellitus. As many people who suffer from Type 2 diabetes may also suffer from obesity, Trulicity can help them lose weight.

There could potentially be serious side effects and adverse effects related to hypoglycemia, or low blood glucose levels, for those who take Trulicity and do not have type 2 diabetes.

Trulicity does not have a proven history for the treatment of individuals with a history of pancreatitis who should consider other antidiabetic therapies. It is not for the treatment of type 1 diabetes mellitus. Trulicity has also not been studied in people with severe gastrointestinal disease, including severe gastroparesis, and is therefore not recommended for use.

Trulicity is contraindicated in people who have a family history of MTC and individuals with MEN 2, as well as in people with a prior serious hypersensitivity reaction to Trulicity (dulaglutide) or any of its ingredients.

There is no data on the presence of Trulicity in human milk and the effects while breastfeeding. Speak with your doctor about the possible risks of taking this medication while pregnant or breastfeeding.

How long does it take for Trulicity to work for weight loss?

Everyone is different and there is no one answer. It is not possible to predict how long it will take to start losing weight once starting to take Trulicity. Given how Trulicity works, you should start to notice a change in appetite within the first few weeks. For best results, Trulicity should be taken in conjunction with diet and exercise.

Trulicity alternatives for weight loss

Wegovy

Wegovy is an injectable prescription drug that is manufactured by Novo Nordisk. It is FDA-approved for weight loss and contains the same active ingredient as Ozempic and Rybelsus, semaglutide. Wegovy is a once-weekly injection and is used in combination with a healthy diet and increased physical activity to manage weight in adults.

RELATED: Wegovy vs Ozempic

Saxenda

Saxenda is an FDA-approved prescription weight loss injection with the active ingredient liraglutide. It is manufactured by Novo Nordisk.

RELATED: Saxenda vs Ozempic

Ozempic

Ozempic is a brand-name prescription medication that is manufactured by Novo Nordisk and is available as an injection. Ozempic isn’t prescribed for weight loss, but weight loss is a possible side effect of taking this medication.

RELATED: Ozempic vs Trulicity, Ozempic for weight loss

Rybelsus

Rybelsus is a brand-name tablet that is manufactured by Novo Nordisk. It isn’t prescribed for weight loss, but weight loss is a possible side effect of taking this medication.

RELATED: Rybelsus vs Ozempic, Rybelsus for weight loss

Victoza

Victoza is also a brand-name medication manufactured by Novo Nordisk that is used once daily to lower blood sugar and A1C. Victoza is not FDA-approved for weight loss. However, due to the way this drug works, Victoza may cause weight loss as a possible side effect.

RELATED: Ozempic vs Victoza

You can also consider Compounded Semaglutide and Compounded Tirzepatide for weight loss.

Other diabetic medications that may cause weight loss

While diabetes medications are not indicated for weight management, weight loss is a positive side effect while using them for many people. These are other diabetic medications that may result in weight loss as a possible secondary endpoint:

Trulicity side effects

Common side effects of Trulicity include :

  • nausea
  • diarrhea
  • vomiting
  • constipation
  • stomach pain (abdominal pain)
  • decreased appetite, indigestion, and fatigue

According to Eli Lilly, “8% to 29% using Trulicity experienced some nausea, which typically occurred during the first 2 to 3 days after they took their first dose.”

Serious side effects may include:

  • inflamed pancreas (pancreatitis)
  • low blood sugar (hypoglycemia)
  • signs and symptoms of low blood sugar
  • serious allergic reactions
  • acute kidney injury
  • severe stomach problems
  • changes in vision

This is not a complete list of all possible side effects. If you experience any side effects or allergic reactions while taking this medication, speak with your doctor right away.

Bottom line

  • Trulicity is not an FDA-approved weight-loss drug. However, taking this medication could result in weight loss due to the way the medication works.
  • Trulicity is known to improve blood glucose levels and blood sugar control in people with prediabetes and type 2 diabetes mellitus.
  • Clinical studies have shown that Trulicity causes greater weight loss in people with a higher initial BMI and higher doses of Trulicity.
  • You can speak with your doctor to find out if Trulicity can be prescribed off-label to help with your weight management goals. It is important for your doctor to consider the risks and benefits of taking this medication, especially if you do not have type 2 diabetes. This medication could be potentially unsafe for those without type 2 diabetes.

Rybelsus for weight loss: does it work?

Rybelsus is a prescription drug used to treat type 2 diabetes and can also help you lose weight. It is not approved for the treatment of weight management. Rybelsus works by helping to reduce the amount of sugar that your body absorbs from food. This can lead to reduced calorie intake and weight loss over time. If you are considering Rybelsus for weight loss, it is important to talk to your doctor about the potential risks and benefits.

Around 70% of American adults are overweight or obese. Overweight and obesity are health conditions that are associated with some of the leading causes of death, including heart disease, diabetes, and stroke. It is also associated with a higher risk of certain types of cancer. Losing 5% to 10% of body weight through exercise and diet has been associated with a reduced risk of cardiovascular disease in adults with overweight and obesity.

What is Rybelsus (semaglutide)?

Rybelsus is an FDA-approved brand-name medication used for the treatment of type 2 diabetes mellitus. Although not approved for weight loss, it is known to help many people lose weight as it works by making you feel full after eating a meal.

Rybelsus belongs to a class of drugs called antidiabetics, Glucagon-like Peptide-1 Agonists (GLP-1 inhibitors) and is manufactured by Novo Nordisk. It is available in tablet form as a starter dose of 3mg to be taken once daily for 30 days, which is then increased to the maintenance dose of 7mg to be taken once daily. If additional glycemic control is needed after at least 30 days on the 7mg dose, the prescribing doctor may increase the dose to 14mg once daily. It should be taken by mouth on an empty stomach when you first wake up, with a sip of plain water.

This medication is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is not for use in people with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis.

Is Rybelsus prescribed for weight loss without diabetes?

Rybelsus is not FDA-approved for weight loss but it can help you lose weight as a side effect.

If you are considering Rybelsus for weight loss, it is important to talk to your doctor about the potential risks and benefits of using this medication for weight loss. It is possible if your prescribing doctor determines it is safe and medically appropriate, that Rybelesus can be prescribed off-label for weight loss.

Does Rybelsus cause weight loss?

Although Rybelsus is not approved for weight loss, there is some evidence that people who take Rybelsus have lost weight while taking the medication.

If you’re considering taking Rybelsus for weight loss, you should receive medical advice from your healthcare provider regarding the potential risks and benefits.

How does Rybelsus cause weight loss?

Rybelsus will make you feel full after eating a meal, which may lead to a reduced intake of calories and weight loss over time.

People with higher initial body weight that are experiencing digestive symptoms may likely lose weight once starting treatment with Rybelsus.

Rybelsus is part of the drug class GLP-1 receptor agonists, also known as incretin mimetic.

It works by mimicking the functions of natural incretin hormones in the body and as a result, it helps to keep the blood sugar levels under control, especially immediately following a meal.

Managing blood sugar also helps to lose weight, especially when combined with a healthy diet and exercise plan.

How much weight can you lose with Rybelsus?

In a 6-month study, people that weighed an average of 194 pounds and took 14 mg of Rybelsus lost around 8 pounds, and people who weighed an average of 196 pounds and took 7 mg of Rybelsus lost around 5 pounds. These results are from a 6-month medical study with 703 adults who were diagnosed with type 2 diabetes. Rybelsus 7mg and 14mg were compared with a sugar pill when both the Rybelsus medication and the sugar pill were added to exercise and diet. The study also found that people who weighed an average of 195 pounds and had taken a sugar pill also lost around 3 pounds. While many people in this study had lost weight, some did gain weight as well.

How long does Rybelsus take to work for weight loss

The study conducted showed that people lost weight over a 6-month period in combination with diet and exercise.

Who can take Rybelsus for weight loss?

Rybelsus is used to manage type 2 diabetes mellitus in adults and also helps to reduce the risk of severe cardiovascular events.

This medication should not be used by anyone who has a family history with MTC, or an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). It should also not be used by anyone who has had a serious allergic reaction to the active ingredient, semaglutide, or any of the ingredients in the medication.

You should only use Rybelsus as prescribed by your healthcare provider. Rybelsus is not FDA-approved for weight loss. However, healthcare professionals may prescribe this medication off-label for weight management if deemed medically appropriate. Off-label use is the prescribing of a drug for an indication other than what the drug was approved to treat by the FDA. If you are interested in taking Rybelsus, tell your doctor about all other prescription drugs, over the counter products, supplements, vitamins, any other medical conditions you have including if you:

  • have or have had problems with your pancreas or kidneys
  • have a history of vision problems related to your diabetes
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed as breastfeeding is not recommended while taking Rybelsus

Rybelsus alternatives for weight loss

Wegovy

Similar to Rybelsus, Wegovy is an injectable medication manufactured by Novo Nordisk that is FDA-approved for weight loss. It contains the same active ingredient as Ozempic and Rybelsus, semaglutide. Wegovy is a once-weekly injection and is used in combination with a healthy diet and increased physical activity to manage weight in adults.

The difference between Wegovy and Ozempic is the dose. Ozempic is prescribed up to 1 mg once per week and Wegovy is prescribed up to 2.4 mg once per week. The higher doses of Wegovy are associated with greater weight loss. A study conducted with Wegovy showed that the average person lost 35 pounds after 68 weeks (approximately 16 months).

RELATED: Wegovy vs Ozempic

Saxenda

Saxenda is another FDA-approved prescription injectable weight loss drug with the active ingredient liraglutide. It is also manufactured by the same manufacturer as Rybelsus, Novo Nordisk. Saxenda helps people to lose weight and keep the weight off.

RELATED: Saxenda vs Ozempic

Ozempic

Ozempic is a brand-name medication that is manufactured by Novo Nordisk. Ozempic is available as an injectable medication, with or without food. It has the same active ingredient as Rybelsus, semaglutide. Ozempic isn’t prescribed for weight loss, but weight loss is a possible side effect due to blood sugar management and the recommended lifestyle changes.

In a study conducted for Ozempic, the average person lost around 8 pounds with the 0.5 mg dose, and the average person lost around 12 pounds with the 1 mg dose.

RELATED: Rybelsus vs Ozempic

Is Rybelsus better than Ozempic for weight loss?

Both medications have been shown to lower body weight by around 6 lbs. However, Ozempic also has some additional benefits. In clinical studies, Ozempic had shown to lower the risk of heart attack, stroke, or death as a result of heart problems in certain people by 26% which hasn’t been confirmed with Rybelsus.

Trulicity

Trulicity is a brand-name prescription drug manufactured by Eli Lilly which is FDA (U.S. Food and Drug Administration) approved for the treatment of adults with type 2 diabetes. It is not approved for weight loss however reduced appetite and weight loss is a possible side effects of Trulicity.

RELATED: Ozempic vs Trulicity

Victoza

Victoza is also a brand-name medication manufactured by Novo Nordisk, taken once daily to lower blood sugar and A1C. Victoza is not FDA-approved for weight loss. However, due to the way this drug works, Victoza may assist with weight loss as well.

RELATED: Ozempic vs Victoza

You can also consider Compounded Semaglutide and Compounded Tirzepatide for weight loss.

Other diabetic medications that may cause weight loss

There are several other diabetic medications that may cause weight loss as a possible side effect while using the medication. Weight loss is typically a desirable effect for people who are diagnosed with type 2 diabetes.

Rybelsus side effects

Common side effects of Rybelsus include :

Serious side effects can include:

  • possible thyroid tumors, including cancer
  • inflammation of your pancreas (pancreatitis)
  • changes in vision
  • low blood sugar (hypoglycemia)
  • kidney problems (kidney failure)
  • serious allergic reactions including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat

This is not a complete list of all possible side effects. If you experience any side effects or allergic reactions while taking this medication, speak with your doctor right away.

Bottom line

  • Rybelsus is not an FDA-approved weight-loss medication. However, it may result in moderate weight loss due to the way the medication works and how it makes you feel full after eating.
  • There are studies that have shown that taking Rybelsus does in fact cause weight loss, despite not being indicated for weight loss.
  • Rybelsus has the same active ingredient as Wegovy, which is an FDA-approved injectable medication for weight loss that is prescribed with a different dose.
  • You can speak with your doctor to find out if Rybelsus can be prescribed off-label to help with your weight management goals.

How much does Ozempic cost with insurance?

Ozempic (semaglutide) is a popular brand-name drug used for treating type 2 diabetes and reducing the risk of major cardiovascular events. There is currently no generic or biosimilar version of Ozempic available.

Ozempic cost with insurance will vary by insurance plan. Learn more about how to find out how much Ozempic will cost with your insurance plan and how to save money on this medication if you have not yet met the coverage gap, have high copays, or if your insurance plan does not cover this medication.

What is Ozempic used for?

Ozempic injection is available in the doses 0.5mg, 1mg, and 2mg. It is an injectable prescription drug used for:

  • improve blood sugar (glucose) in adults with type 2 diabetes mellitus, along with diet and exercise
  • reducing the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes mellitus with known heart disease.

It is not known if this medication can be used in those who have had pancreatitis. Ozempic is not for use in people with type 1 diabetes and it is not known if it is safe and effective for use in children under 18 years of age.

The active ingredient in Ozempic is semaglutide. Semaglutide is in a class of drugs known as GLP-1 receptor agonists and it works by helping your body release more insulin and improving blood sugar control.

Ozempic is not approved for weight loss. Some people may lose weight while taking Ozempic because the medication is intended to lower blood sugar levels and improve glycemic control. Some doctors may prescribe Ozempic for weight loss off-label. Wegovy and Saxenda are similar drugs to Ozempic and are approved for weight management.

Common Ozempic side effects include nausea, constipation, diarrhea, indigestion, low blood sugar levels, and reactions at the injection site. Speak to your healthcare professional if you experience any serious allergic reactions while taking this medication.

Is Ozempic covered by insurance?

Ozempic is covered by most Medicare plans and health insurance plans. It is possible that Ozempic is covered by your health insurance plan if it is prescribed by your doctor for the treatment of diabetes. Insurance coverage and reimbursement for Ozempic vary depending on the terms of each individual health insurance plan. Contact your health insurance company or speak with your pharmacist to verify coverage and reimbursement for Ozempic before you start treatment.

Insurance companies will use a drug formulary, which is an approved list of medications that are covered at tiered prices. If Ozempic is placed on a higher tier on the formulary, or if Ozempic is considered as a non-preferred drug in the formulary, that may result in a higher copay or no coverage at all for this medication.

As well, if your insurance plan has a deductible for prescription medications, you may be required to pay the full list price for Ozempic until you reach the coverage gap (out-of-pocket maximum).

You can also find out if Ozempic is covered by your insurance by logging into your health insurance company’s online portal and finding the “Price a Medication” link that is typically located in your Pharmacy Benefits section. Make sure to review any possible restrictions, including prior authorization, quantity limits, or step therapy. You should also check if you have a deductible, which requires that you pay the full list price for Ozempic until you reach the coverage gap (out-of-pocket) limit.

RELATED: Insurance and NiceRx

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How much does Ozempic cost with insurance?

Many health insurance plans will cover all or some of the cost of Ozempic, however, the copay amount will vary by plan. You may still be responsible to pay for part of the Ozempic price, depending on your insurance policy’s terms.

Novo Nordisk offers an Ozempic savings card that can reduce the cost of Ozempic by up to $100 per month. Eligible patients who have private or commercial insurance, such as insurance received through an employer, may be eligible to pay as little as $25 for a 1-month, 2-month, or 3-month Ozempic prescription. Novo Nordisk states the maximum savings of $150 per 1-month prescription, $300 per 2-month prescription, or $450 per 3-month prescription). The Ozempic savings card is valid on prescriptions for a 1-month, 2-month, or 3-month supply, and can be used for up to 24 months from the date of activation. These eligibility requirements may change and it is recommended to check for the latest guidelines on the manufacturer’s website.

For those with high copays or without insurance coverage for Ozempic, there are alternative medications that can be considered. Speak with your healthcare provider about possible alternatives that are available as lower-priced generics including metformin, meglitinides, sulfonylureas, bile acid sequestrants, and alpha-glucosidase inhibitors. These lower-cost generic drugs are FDA-approved for lowering blood glucose. However, these alternatives may not be considered an adequate substitute for Ozempic.

You should not take any over-the-counter medications or supplements as a substitute for prescription medications to control blood sugar levels.

If you do not have insurance coverage for Ozempic, or if this medication is not covered by your insurance plan, the cost of Ozempic can be expensive. Novo Nordisk’s website states that the list prices (out-of-pocket cost) for Ozempic 0.25 or 0.5 mg (1 x 1.5-mL pen) and 1 mg (1 x 3-mL pen) are $851.60 for a 30-day supply (around $213 per week depending on the prescribed dose).

Compare Ozempic alternative prices

Brand-drug name (chemical name)Average weekly cost
Adlyxin (lixisenatide)$300 average weekly cost (1 dose daily)
Bydureon BCise (exenatide)$190 average weekly cost (1 dose weekly)
Byetta (exenatide)$190 average weekly cost (2 doses daily)
Victoza (liraglutide)$210-310 weekly cost (1 dose daily)
Trulicity (dulaglutide)$300 weekly cost (1 dose weekly)
Rybelsus (semaglutide)$310 weekly cost (1 dose daily)

Note: Prices are provided as estimates only and are subject to change.

RELATED: Ozempic vs Trulicity

How to save on Ozempic

With an estimated annual cash price of around $10,000 ($850 per month) without insurance, Ozempic is a very expensive medication, especially for people who do not have adequate insurance coverage. It can also be an expensive medication for those with insurance and high copays. Fortunately, there are options available to get Ozempic at a lower price:

  • Consider Compounded Semaglutide which is the compounded version of Ozempic
  • Check if your insurance plan will cover the cost of Ozempic.
  • If you have private or commercial insurance, such as insurance received through an employer, you may be eligible to pay as little as $25 for a 1-month, 2-month, or 3-month Ozempic prescription. Find out if you are eligible for the Ozempic savings card. Restrictions may apply. Check the manufacturer’s website as terms and conditions may change.
  • If your insurance plan will not cover the cost of Ozempic, or will only cover part of the cost and require you to pay a high copay, check around at multiple pharmacies for the lowest price for this medication. The local pharmacy doesn‘t always offer the lowest price. A study conducted by Consumer Reports estimates that the retail prices for medications can vary by as much as 10 times from one pharmacy to another.
  • Try using an Ozempic coupon or prescription drug discount card.
  • If your current insurance plan doesn’t cover Ozempic or has a high copay for this medication, look for a new health plan that covers Ozempic with a lower copay.
  • Check if you qualify for enrollment in a patient assistance program offered by the manufacturer or other organizations.
  • If eligible, enroll in Medicaid. Some Medicaid plans may cover the cost of Ozempic.
  • Get medical advice from your healthcare provider about alternative treatment options. Ozempic is a prescription drug that belongs to a drug classification called GLP-1 agonists which are used to treat type 2 diabetes. There are several lower-cost alternative drugs that your healthcare provider may consider to help you save money on your treatment.

Is Xarelto generic available?

Xarelto is an expensive prescription drug and there is currently no generic version of Xarelto available. It is not yet definitively known when the first generic version of Xarelto will become available. Learn more about the earliest potential release date for generic Xarelto and options to save money on this medication.

What is Xarelto?

Xarelto (rivaroxaban) is a blood thinner (anticoagulant) that is approved to be prescribed to adults for:

  • reducing the possible risk of blood clots and stroke for people that have atrial fibrillation which is not the result of a heart valve problem
  • treating blood clots in the veins of the legs (deep vein thrombosis or DVT) and also the lungs (pulmonary embolism or PE)
  • reducing the risk of getting blood clots from reoccurring for people who are at risk for DVT or PE after being treated for blood clots for a minimum of 6 months
  • helping with the prevention of blood clots in the lungs and legs for people that recently had hip replacement surgery or knee replacement surgery
  • helping with the prevention of blood clots for people that have been treated at a hospital for an acute illness and who after discharge are at risk of getting blood clots as a result of the loss of or reduced capability to move around and other potential risks for getting blood clots, and are not at a high risk of bleeding

Xarelto is approved for use in children for:

  • treating blood clots or reducing the risk of blood clots from happening again after receiving at least 5 days of treatment with injectable or intravenous medicines used for the treatment of blood clots
  • helping to prevent blood clots in children that are 2 years of age and older with congenital heart disease after the Fontan procedure

This medication is also used for adults with a low dose of aspirin for:

  • reducing the risk of serious heart problems, heart attack, and stroke in those with coronary artery disease (a medical condition in which the blood supply to the heart is blocked or reduced)
  • reducing the risk of a sudden decrease in blood flow to the legs, major amputation, serious heart problems or stroke in adults with peripheral artery disease (a medical condition in which the blood flow to the legs is reduced)

The medication works by slowing your body’s ability to clot by selectively blocking one of the clotting factors found in your blood, an enzyme that is called Factor Xa (“10a”).

The active ingredient in Xarelto is rivaroxaban. Rivaroxaban is part of the anticoagulant drug class, specifically the factor Xa inhibitors (blockers).

Xarelto is manufactured by Janssen Pharmaceuticals, a subsidiary of Bayer. It was first approved by the FDA in 2011.

Are there cheaper alternatives to Xarelto?

There are other prescription medication alternatives to Xarelto available. These medications have different strengths, dosages, and indications.

Cheaper alternatives to Xarelto

Drug nameApproved usesSide effectsGeneric available
Arixtra (fondaparinux)Prevention and treatment of DVT and PEAnemia, rash, bleeding
AspirinPrevention of heart attacks and strokesHeartburn, stomach pain, nausea
Brilinta (ticagrelor)Prevention of heart attacks and strokes in CADDizziness, nosebleeds, nausea
Eliquis (apixaban)Prevention and treatment of DVT and PE, prevention of stroke in AFibBleeding, nausea, bruisingapproved
Fragmin (dalteparin)Prevention of DVT and treatment of heart attackBleeding, bruising, and pain at the injection site
Jantoven (warfarin)Prevention and treatment of DVT and PE, prevention of stroke in AFib and after a heart attackBleeding, vomiting, nausea
Lovenox (enoxaparin)Prevention and treatment of DVT, treatment of heart attackAnemia, nausea, diarrhea
Plavix (clopidogrel)Prevention of heart attacks and strokes in CAD and PADBruising, diarrhea, itching
Pradaxa (dabigatran)Prevention and treatment of DVT and PE, prevention of stroke in AfibBleeding, stomach pain, indigestion

Other common alternatives to Xarelto also include Bevyxxa (betrixaban), Angiomax (bivalirudin), Effient (prasugrel), Iprivask (desirudin), and Savaysa (edoxaban).

RELATED: Xarelto alternatives: which other blood thinners can I take?, FDA approves the first Eliquis generic, apixaban

How much will the generic cost once it’s available?

As there are no generic alternatives currently on the market, it is not possible to estimate the price of generic Xarelto. Nonetheless, generic drugs are typically much less expensive than brand-name drugs, so consumers should expect to save money on this medication once the generic alternative is available for sale.

When will generic Xarelto become available?

There is no estimated timeframe for generic Xarelto to become available. However, the drug patents for Xarelto are expected to expire sometime in 2024, which is the earliest time Xarelto generic will become available for sale. It’s possible that the manufacturer may obtain authorization to extend the patent which commonly occurs, so it’s not possible to definitively estimate the release date for the first generic.

How do you take Xarelto (rivaroxaban)?

You should take Xarelto exactly as instructed by your healthcare provider. The usage of this medicine will vary by indication. You should not stop taking this medicine unless instructed by your prescribing doctor.
The manufacturer recommends that the medication be taken accordingly:

  • Atrial Fibrillation which is not the result of a heart valve problem: once per day
  • Blood clots in the lungs or  veins of your legs: once or twice per day
  • Knee or hip replacement surgery: once per day
  • Blood clots in individuals who were hospitalized for acute illnesses: once per day
  • Reducing the risk of heart attack, serious heart problems, and stroke in coronary artery disease: twice per day with aspirin 75mg to 100mg once per day as prescribed by your healthcare provider.
  • Reducing the possible risk of a sudden reduction in blood flow to the legs, major amputation, serious heart problems or stroke in people with peripheral artery disease: twice per day with aspirin 75mg to 100mg once per day as prescribed by your healthcare provider.

Xarelto is can be taken with food or without food. If you forget to take your Xarelto medication, take it once you remember. If it is almost time for your next dose, do not take the missed dose and take your next dose at the regular time. Do not take two doses of Xarelto at the same time.

Xarelto side effects

The most common Xarelto side effect in adults was reported as bleeding.

The most commonly reported side effects in children:

  • bleeding
  • cough
  • vomiting
  • inflamed gut and stomach

Other possible serious side effects of Xarelto are:

  • increased risk of blood clots if you stop taking the medication – individuals with atrial fibrillation that is not caused by a heart valve problem (nonvalvular) are at an increased risk of forming a blood clot in the heart

Xarelto should not be taken by people with artificial heart valves. This medication could also pass into breast milk so always consult your healthcare provider before breast-feeding if you are taking this medication.

Do not stop taking the medication without first speaking with your prescribing doctor. Stopping to take Xarelto may increase your risk of having a stroke.

Speak with your prescribing doctor about all of the possible drug interactions with any other prescription drugs, over-the-counter products, vitamins, and supplements you are taking. These are not all of the possible side effects of Xarelto. You should always seek the medical advice of a licensed healthcare professional for any questions or concerns relating to your medical condition or treatment.

How much does Xarelto cost?

The estimated cost for Xarelto tablet 20mg with no insurance is around $550 for 30 tablets. The manufacturer’s website states that eligible patients with commercial insurance pay $10 for each 30-day and 90-day supply of Xarelto, with no program benefit limits for the first 90 days, and a $200 limit for each 30-day supply thereafter, with a maximum benefit of $3,400 per calendar year. Those with government insurance, for example, Medicare Part D enrollees, pay $85 for a 30-day supply of Xarelto, or $240 for a 90-day supply of Xarelto, plus sales tax if applicable.

Why is Xarelto so expensive?

Xarelto is so expensive because it is a brand-name medication with no generic alternative available. Brand-name drugs are always more expensive than generic drugs. In contrast, the FDA-approved generic version of Xarelto will be much cheaper once it becomes available.

FDA approves Humira biosimilar, adalimumab

Humira is an expensive biologic medicine that is widely used to manage symptoms of rheumatoid arthritis (RA) and several other autoimmune conditions. It’s a tumor necrosis factor (TNF) blocker drug and is one of the top-selling prescription drugs in the world. The manufacturer, Abbvie, reported net revenue of $17.33 billion in 2021 in the United States for Humira.

As of July 2022, the FDA has approved 7 Humira biosimilars. Learn more about which Humira biosimilars options will become available in the near future for you to start saving on this medication.

What is Humira (adalimumab)?

Humira is a monoclonal antibody that binds to TNF alpha, inactivates TNF alpha receptors, and reduces the effects of a substance in the body that causes inflammation.

It is FDA-approved for the treatment of:

  • Moderate to Severe Rheumatoid Arthritis
  • Moderate to Severe Chronic Plaque Psoriasis
  • Moderate to Severe Crohn’s Disease
  • Moderate to Severe Pediatric Crohn’s Disease
  • Moderate to Severe Ulcerative Colitis
  • Moderate to Severe Pediatric Ulcerative Colitis
  • Psoriatic Arthritis
  • Moderate to Severe Hidradenitis Suppurativa
  • Ankylosing Spondylitis
  • Moderate to Severe Polyarticular Juvenile Idiopathic Arthritis
  • Non-Infectious Intermediate, Posterior, and Panuveitis

Humira is manufactured by Abbvie and was first approved by the FDA in 2002. Sales of AbbVie’s blockbuster drug Humira have accelerated since the date it was initially approved.

Which biosimilar versions of Humira have been approved by the FDA?

The following Humira biosimilars have been approved by the FDA:

Biosimilar nameApproval dateManufacturer
Yusimry (adalimumab-aqvh)December 2021Coherus BioSciences
Hulio (adalimumab-fkjp)July 2020Viatris
Abrilada (adalimumab-afzb)November 2019Pfizer
Hadlima (adalimumab-bwwd)July 2019Merck & Co
Hyrimoz (adalimumab-adaz)October 2018Sandoz
Cyltezo (adalimumab-adbm)August 2017Boehringer Ingelheim
Amjevita (adalimumab-atto)September 2016Amgen

What’s the difference between a biosimilar and a generic drug?

A biosimilar is a biologic medical product that is similar to another already-approved biological product, or “reference product.” Both are derived from living organisms and are manufactured through highly controlled biotechnology processes. Generic drugs are copies of brand-name drugs and are approved by the U.S. Food and Drug Administration (FDA) to be interchangeable with the brand-name version.

While generic drugs must have the same active ingredient as the brand-name drug, biosimilars may have minor differences in their manufacturing process or inactive ingredients. Biosimilars must also meet the FDA’s safety, efficacy, and quality standards.

The FDA has a pathway for approving biosimilars that demonstrates they are highly similar to an already-approved biological product and have no clinically meaningful differences in terms of safety and effectiveness from the reference product. There are currently several biosimilars approved by the FDA, and many more are in development. Unlike generic drugs, biosimilars are not identical to the reference biological drug. As biological drugs are manufactured using living cells and processes, the biosimilar drug may have minor differences from the reference biologic product. Nonetheless, biosimilars must prove that these differences are not clinically meaningful to obtain FDA approval.

RELATED: Biosimilar vs generic

Is Generic Humira available?

Unfortunately, there is no generic Humira available. As Humira is a biologic product, lower-cost biosimilar versions of Humira are expected to become available sometime in 2023.

Is there a cheaper alternative to Humira?

There are several other medications that work similarly to Humira or treat similar conditions. The prices of these medications will vary by your insurance plan. Check with your insurance provider and find out what is your copay and deductible for these medications. Always check with your healthcare provider before considering switching to any other medication.

How much will Humira biosimilar cost?

As there are no biosimilar versions of Humira yet on the market in the United States, it is not yet possible to know the estimated price. However, 7 biosimilar versions of Humira have already been approved by the FDA by separate drugmakers that will likely compete for market share which ultimately leads to lower prices for consumers, as is the case with generic drugs.

When will Humira biosimilar become available?

Amjevita and Cyltezo were the first biosimilar versions of Humira to be approved by the FDA. Although the first Humira biosimilar, Amjevita, was approved by the FDA in 2016, the manufacturer of Amjevita, Amgen, agreed to a settlement with the manufacturer of Humira, Abbvie, not to sell the product in the United States until January 31, 2023. Similarly, Pfizer had also reached a settlement agreement with Abbvie that prohibits the sale of Pfizer’s biosimilar, Abrilada, until November 20, 2023. As a result, the first expected version of Humira biosimilar is expected sometime in 2023.

How do you use Humira?

Humira should be stored in its original packaging in a refrigerator (36°F to 46°F) until you are ready to start using it. You can leave your Humira prefilled syringe or pen out of the refrigerator for 15 to 30 minutes before injecting it. You should not use the product if the liquid is cloudy or discolored, or if it has flakes or particles in it.

When using the Humira Pen:

  • Do not remove the caps until right before you are ready for the injection.
  • When the plum-colored button on the Humira Pen is pressed to give your dose, you will hear a loud click which means that the injection has started.
  • The injection is complete when the yellow indicator fully appears in the window view and stops moving.

When using Humira prefilled syringe:

  • Always hold the prefilled syringe by the body of the syringe with the needle pointing down.
  • Do not crush or drop Humira. The prefilled syringe is glass.

If you forget to take Humira, inject a dose as soon as you remember. You should then take your next dose of Humira at your regular scheduled time.

What are the side effects of Humira?

The most common side effects of Humira are:

  • injection site reactions (pain, redness, rash, swelling, itching, or bruising)
  • upper respiratory infections (sinus infections)
  • headaches
  • rash
  • nausea

Taking Humira can also increase your risk for serious infections that could lead to a hospital stay or death.

How much does Humira cost?

Humira costs up to $77,000 per year for those without insurance and up to $6,000 per year for those with insurance. The price of Humira continues to increase year after year.

Why is Humira so expensive?

Humira is so expensive because it is a brand-name medication with no biosimilar or generic alternatives available for sale. Humira has been a blockbuster TNF inhibitor drug for Abbvie. Brand-name drugs are always more expensive than generic drugs. The FDA-approved biosimilar alternatives to Humira will likely be much less expensive than Humira once they are available for sale.

Why is Jublia so expensive?

Jublia is an expensive topical antifungal prescription drug used to treat toenail fungus. It is an effective treatment for fungal infections.

Around 25% of the population has athlete’s foot and one of the primary causes of athlete’s foot is toenail fungal infections that are untreated.

Americans pay more for prescription drugs than any other country. There are currently no generic alternatives to Jublia. Find out why Jublia is so expensive and what options are available to save money on this medication.

What is Jublia (efinaconazole)?

Jublia is an FDA-approved prescription drug that is formulated to reach the site of onychomycosis, for the topical treatment of toenail fungus on nails and the surrounding skin. It was approved by the FDA (U.S. Food and Drug Administration) in 2014. This medication works better than most over-the-counter alternatives.

The active ingredient in Jublia is efinaconazole and is available as a 10% topical solution. This medication is manufactured by Valeant Pharmaceuticals.

Use Jublia at the same time and place each day, for example in the morning or before bed. The recommended dosage is one drop applied to the affected toenail(s), with a second drop applied to the affected big toenail(s) once daily, preferably at bedtime. Jublia should be applied once per day to the affected toenail for 48 weeks. Only use Jublia as directed by your doctor. The amount of time it takes for a healthy nail to grow back varies from person to person.

Fungal infections of the nails are difficult to treat. Jublia is a new medication that has shown to be effective in clinical trials. In Study 1, Jublia had achieved a 17.8% complete cure rate, and in Study 2, Jublia had achieved a 15.2% complete cure rate.

You can prevent fungal infections by keeping your feet clean and dry. Wear socks made from natural fibers, such as cotton. Avoid walking barefoot in public places, such as locker rooms or pool areas. Change your shoes and socks daily, and alternate shoes to allow them to air out between wearings.

Jublia side effects

Jublia can cause irritation at the treated site. The most common side effects of Jublia include:

  • ingrown toenail
  • itching
  • redness
  • swelling
  • stinging or burning
  • blisters
  • pain

If you experience any side effects or possible signs of an allergic reaction while taking Jublia, speak with your healthcare provider right away.

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How much does Jublia cost?

The estimated retail price for Jublia Topical Solution 10% without insurance is around $685 for a 4 ml bottle.

Jublia’s cost can vary depending on your health insurance coverage for this medication. Contact your insurance broker to find out if your health insurance plan covers Jublia under its formulary. You should also find out from your insurance company if there are any deductibles and copays for this medication.

Each insurance plan has its own drug formulary that specifies which drugs it will cover. Some insurance plans may have Jublia on a higher tier which means that this prescription drug may have to pay a higher coinsurance or copayment. It’s also possible that Jublia may not be covered at all by your insurance plan.

The manufacturer has partnered with Walgreens and other participating pharmacies to offer a discount copay coupon for Jublia to commercially insured patients once the deductible is met. Most eligible individuals who are commercially insured will pay as little as $0 copay for their first prescription and eligible refills.

Those with commercial insurance without prescription drug coverage for Jublia and uninsured patients who are paying out-of-pocket will pay as little as $65 copay for the first Jublia prescription and eligible refills.

This offer is not valid for individuals with insurance coverage whole or in part by any state, federal, or other government programs, including Medicare, Medicaid, TRICARE, Veterans Administration Benefits, CHAMPIS, Department of Defense health coverage, and the Puerto Rico Government Health Insurance Plan.

Why is Jublia so expensive?

Jublia is so expensive that CVS decided to restrict the use of this medication. There are a few reasons why Jublia is an expensive prescription drug.

The generic version of Jublia is not yet available

Generic Jublia (efinaconazole) is not yet available in the United States. The earliest possible date a generic version will become available is sometime in 2030, which is when the patents are expected to expire.

Generic drugs are usually less expensive than brand-name drugs. When a generic version of efinaconazole becomes available, there will likely be more competition and the price of efinaconazole may go down.

RELATED: Brand vs generic drugs

Patent law protection

Jublia is covered by multiple patents that protect the drug from generic competition until 2030. This is why Jublia is so expensive, as there is no generic version of Jublia yet available.

The manufacturer of Jublia, Valeant Pharmaceuticals, has the exclusive rights to market this medication for 20 years from the initial date it applied for patent protection.

There are also other patents that protect Jublia from generic competition. These include patents for the use of Jublia to treat onychomycosis, patents that cover the specific formulation of Jublia, and a patent that covers the delivery system (spray bottle) used to apply Jublia.

The FDA approval process for a new drug is lengthy and expensive, so pharmaceutical companies will charge high prices for their medication in an attempt to recoup their research and development costs.

Generally, most drug patents will expire 20 years after the initial application date. Pharmaceutical manufacturers that hold the patent for the drug can also apply for an extension on the patent protection by reformulating the drug, changing how to drug is administrated, or simplifying the dose, which is commonly known as a “new use” or “new formulation” patent. Extending the patent delays the availability of generic alternatives for the medication and also delays the introduction of lower-cost generic alternatives.

Unregulated prescription drug prices in the United States

Unlike other developed countries, the United States government doesn’t regulate the price of prescription drugs. This means that pharmaceutical companies are free to set their own prices for their medications.

The cost of Jublia is determined by Valeant Pharmaceuticals, the manufacturer of Jublia. The price of Jublia may be increased at any time and there is no limit on how often or by how much the price can be increased.

Valeant Pharmaceuticals is known for aggressively raising the prices of its medications. Since 2014, the company has raised the prices of more than 200 drugs by an average of 66%.

It typically costs a pharmaceutical company billions of dollars to successfully introduce a new drug to market. The cost of prescription drugs is determined by many factors, including:

  • The cost of research and development
  • The price of the raw materials needed to make the medication
  • The demand for the drug
  • Marketing and advertising costs
  • Profit margins
  • The cost of research and development

A study by RAND concluded that prescription drug prices in the United States are on average 2.56 times higher than in other OECD countries.

How do I save on Jublia?

Jublia is an expensive toe fungus drug, especially for those who do not have any prescription drug coverage for this medication. Fortunately, there are several options that could possibly help you save money:

  1. Jublia Copay Card – the manufacturer offers a discount copay card to commercially insured patients once the deductible is met and most eligible individuals who are commercially insured will pay as little as $0 copay for their first prescription and eligible refills. Those with commercial insurance without prescription drug coverage for Jublia and uninsured patients who are paying out-of-pocket will pay as little as $65 copay for the first Jublia prescription and eligible refills. Make sure to check the offer on the website as the terms and eligibility requirements can change.
  2. Patient assistance programs – find out if you are eligible for enrollment into a Jublia patient assistance program.
  3. Ask your prescribing doctor for free samples of Jublia – many pharmaceutical companies provide healthcare providers with free samples to provide to their patients in order to help them get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative treatment options – ask your prescribing doctor if there are any lower-cost alternatives to Jublia including other topical treatments or oral antifungal medications like Lamisil (terbinafine) and its generic equivalent.
  5. Shop around for the lowest price at multiple mail-order pharmacies – the price for Jublia can vary by pharmacy and may not be the cheapest at your local pharmacy, so you should always check pricing at multiple pharmacies to find the lowest possible price.
  6. Jublia coupons – find out if there is a Jublia manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Jublia.

Ozempic for weight loss

Ozempic is prescribed to adults with type 2 diabetes mellitus to help lower blood glucose and A1C. Ozempic is not FDA-approved for weight loss. However, it is used off-label for weight loss in people who are diagnosed with Type 2 diabetes and cardiovascular risk. Off-label use refers to the unapproved use of an approved drug, for example using a drug for a disease or medical condition that it is not approved to treat.

Approximately 70% of American adults are obese or overweight. Obesity and overweight are serious health conditions associated with some leading causes of death, including heart disease, stroke, and diabetes. It is also associated with an increased risk of certain types of cancer. Losing 5% to 10% of body weight through diet and exercise has been associated with a reduced risk of cardiovascular disease in adults with obesity or overweight.

What is Ozempic (semaglutide)?

Ozempic is a brand-name medication used to treat type 2 diabetes mellitus. It is a prescription injection taken once per week.

The active ingredient in Ozempic is semaglutide. Ozempic (semaglutide) belongs to a class of drugs called glucagon-like peptide 1 (GLP-1) analogs. GLP-1 analogs increase the incretins levels, therefore they are called incretin mimetics. These drugs increase insulin levels when needed and reduce the unnecessary amounts of glucose that are produced by the liver. The benefits of GLP-1 analogs are: reducing the speed at which the stomach digests and empties (delayed gastric emptying), appetite reduction, helping lose weight, decreased cholesterol and blood pressure

Ozempic is injected once per week into the thigh, upper arm, or abdomen. Ozempic is manufactured by Novo Nordisk.

Does Ozempic cause weight loss?

Ozempic is not FDA-approved for the treatment of weight loss. However, there is some evidence that people who take Ozempic have experienced weight loss.

If you’re considering taking Ozempic for weight loss, seek medical advice from your doctor or healthcare provider about the potential risks and benefits. They can help you decide if this medication is right for you.

How does Ozempic cause weight loss?

Ozempic is a GLP-1 agonist which is the body‘s natural way of controlling blood sugar. Managing blood sugar helps to lose weight, especially when combined with a healthy diet and exercise plan. Ozempic prompts your pancreas to produce more insulin when blood glucose levels are high. It also helps prevent the liver from making and releasing too much sugar into the bloodstream. Gastric emptying (the rate at which food leaves the stomach) is slowed down. All of these functions result in weight loss.

How much weight can you lose with Ozempic?

According to the manufacturer, adults taking Ozempic lost up to 14 pounds. In the specific population studied for Ozempic, the average person lost around 8 pounds with the 0.5 mg dose, and the average person lost around 12 pounds with the 1 mg dose.

Who can take Ozempic for weight loss?

Ozempic is used to manage type 2 diabetes mellitus in adults. It also reduces the risk of severe cardiovascular events. Ozempic should not be used in adults with a history of pancreatitis, and should not be used to treat type 1 diabetes mellitus.

Ozempic can decrease appetite and many people with diabetes who use this medication will lose weight.

Ozempic is not FDA-approved for weight management. However, doctors may prescribe this medication off-label for weight management. Off-label use is defined as the prescribing of a drug for an indication other than what the drug was approved to treat by the FDA.

You should only use Ozempic as prescribed by your healthcare provider. Ask your doctor about using Ozempic for weight management.

Ozempic alternatives for weight loss

Wegovy

Like Ozempic, Wegovy is a weight loss drug manufactured by Novo Nordisk and the active ingredient is semaglutide. Wegovy is a once-weekly injection and is used in combination with a healthy diet and increased physical activity to manage weight in adults with one weight-related comorbidity (ie. hypertension, dyslipidemia, or type 2 diabetes mellitus) with initial body mass index (BMI) ≥30 kg/m2 (obesity) or ≥27 kg/m2 (overweight).

The difference between Wegovy and Ozempic is the dose. The dosing for Ozempic is up to 1 mg once per week and the dosing for Wegovy is up to 2.4 mg once per week. The higher doses of Wegovy are associated with greater weight loss. In the specific population that was studied for Wegovy, the average person lost 35 pounds after 68 weeks (approximately 16 months). In contrast, in the specific population studied for Ozempic, the average person lost around 8 pounds with the 0.5 mg dose, and the average person lost around 12 pounds with the 1 mg dose.

RELATED: Wegovy vs Ozempic

Saxenda

Saxenda is an FDA-approved prescription injectable weight loss drug with the active ingredient liraglutide and is manufactured by Novo Nordisk. It helps people to lose weight and keep the weight off.

RELATED: Saxenda vs Ozempic

Rybelsus

Rybelsus is a brand-name medication that is manufactured by Novo Nordisk. Rybelsus is available in tablet form and is taken by mouth once daily, with or without food. Rybelsus isn’t prescribed for weight loss, but weight loss is a possible side effect due to blood sugar management and the recommended lifestyle changes.

RELATED: Rybelsus vs Ozempic

Trulicity

Trulicity is a brand-name drug manufactured by Eli Lilly. It is an FDA (U.S. Food and Drug Administration) approved prescription drug for adults who have type 2 diabetes. It is not approved for weight loss. Reduced appetite and thus weight loss is a possible side effect of Trulicity.

Results from a 40-week study that compared people who took Ozempic and Trulicity showed that the people who took Ozempic lost more than double the weight than with Trulicity in adults who were taking metformin in combination.

RELATED: Ozempic vs Trulicity

Victoza

Victoza is a brand-name medication that is manufactured by Novo Nordisk. It is a once-daily medication prescribed to lower blood sugar and A1C. Victoza is not meant to be used specifically for weight loss, however, due to the way this drug works, it may assist adults to lose weight.

RELATED: Ozempic vs Victoza

Compounded Semaglutide

Compounded Semaglutide is the compounded version of Ozempic and Wegovy. It is available through NiceRx.

Compounded Tirzepatide

Compounded Tirzepatide is the compounded version of Mounjaro and Zepbound. It is available through NiceRx.

Other diabetic medications that may cause weight loss

There are other diabetic medications that have been shown to cause weight loss. Weight loss can also be a desirable effect for people who are diagnosed with Type 2 diabetes. Diabetic medications that may cause weight loss include:

Ozempic side effects

Common side effects of Ozempic include :

Serious side effects are rare but can include:

  • diabetic retinopathy
  • pancreatitis
  • Kidney disease or kidney problems
  • Serious allergic reactions.
  • Increased cholesterol levels
  • hypoglycemia (low blood sugar)
  • acute gallbladder disease
  • Possible thyroid tumors, including cancer

Gastrointestinal adverse reactions occurred more frequently among people receiving Ozempic 2 mg (34.0%) vs Ozempic 1 mg (30.8%).

Ozempic is not right for everyone. Be sure to tell your doctor or healthcare professional about all of your medical conditions and allergies before taking this diabetes drug. Discuss with your doctor if you are on any other medications (including over-the-counter), supplements, or vitamins. Tell your doctor if you are pregnant or breastfeeding. This diabetes medication may be harmful to an unborn baby.

Ozempic drug interactions

Ozempic can interact with vitamins, drugs, or herbs that you are taking which can change the way a drug is meant to work or cause harm. It is possible that Ozempic can interact with oral medications as it affects gastric emptying which can impact the effectiveness of oral medications.

Ozempic can be added to other diabetes medications (ie Metformin, insulin sulfonylurea) but the dosage may need to be lowered since Ozempic works to lower your blood sugar levels so it is important to discuss with your doctor.

Your physician should review and manage all of your medications carefully to avoid any issues. Always discuss with your doctor about all supplements, herbs, vitamins, or medications that you take and discuss if there is a possibility of any drug interactions.

Is Ozempic used for cardiovascular disease?

Cardiovascular disease includes conditions that affect the heart and blood vessels.

Ozempic is FDA-approved to be prescribed to adults with type 2 diabetes mellitus to reduce the risk of major cardiovascular events. In a phase III clinical trial examining cardiovascular and other long-term outcomes with semaglutide in patients with type 2 diabetes, subjects were randomized to Ozempic once weekly or placebo, and results showed that Ozempic significantly reduced the risk of Major Adverse Cardiovascular Event (MACE).

If you have type 2 diabetes and are at risk for cardiovascular disease, your doctor may prescribe Ozempic to help reduce your risk of cardiovascular death.

Does Ozempic reduce blood pressure?

Ozempic is not FDA-approved to treat high blood pressure. Type 2 diabetes increases your risk of cardiovascular events and disease including high blood pressure (hypertension). Controlling your diabetes through medication and in combination with healthy eating and exercise does help to reduce that risk.

When should I take Ozempic?

Ozempic is usually taken once weekly with or without food. Your doctor will determine the best dose for you based on your medical conditions and response to treatment.

The manufacturer recommends starting at a dose of 0.25 mg once weekly. After 4 weeks, the dose of Ozempic can be increased to 0.5 mg. If needed, the dose can be increased to 1 mg once weekly after at least 4 weeks, up to a maximum of 2 mg.

If you forget to take Ozempic at the scheduled time, the missed dose can be injected within 5 days.

Bottom line

  • Ozempic is not indicated for weight loss, but it may result in moderate weight loss for people who take this medication alone or in combination with other medications such as metformin or sulfonylurea.
  • Although not approved for weight loss, Ozempic has proven in clinical trials to result in greater weight loss compared to other popular diabetes medications including Trulicity, Bydureon, Januvia, and Lantus.
  • In addition to possible weight loss, Ozempic can also have a positive effect on your cardiovascular (heart) health and reduce the risk of death from heart-related conditions.
  • You can speak with your doctor to find out if Ozempic can be prescribed off-label for weight management.

What foods to avoid while on Victoza

Victoza (liraglutide) is an injectable medicine that is used to lower blood sugar levels in adults and children (10 years of age and up) with type 2 diabetes mellitus.

Victoza is a once-daily, non-insulin medication that is taken to lower A1C. Taking Victoza helps the pancreas produce additional insulin by helping important cells called beta cells to help control blood glucose levels by making and releasing insulin.

Although there are no specific foods that you must avoid while on Victoza, there are diet recommendations you can follow if you have been diagnosed with type 2 diabetes.

What is Victoza (liraglutide)?

Victoza is an FDA-approved prescription drug used to treat Type 2 diabetes and is also approved to reduce the risk of complications from heart disease in people with Type 2 diabetes and heart disease. It belongs to a group of diabetes drugs called glucagon-like peptide-1 receptor agonists (GLP-1).

The active ingredient of Victoza is liraglutide. This medication is manufactured by Novo Nordisk. It is an injectable prescription drug that is administered under the skin (subcutaneously). It is available in the dosage form 18MG/3ML Solution Pen-injector.

The main use of Victoza is to decrease blood sugar along with diet and exercise in adults and children who are 10 years of age and up with type 2 diabetes mellitus. Victoza also reduces the risk of major cardiovascular events associated with type 2 diabetes mellitus with known heart disease (ie heart attack, stroke, or death).

Victoza is not meant to be used to treat type 1 diabetes.

RELATED: Ozempic vs Victoza, Victoza vs Trulicity

How does Victoza work?

Victoza works similarly to glucagon-like peptide-1 (GLP-1) which is a hormone naturally produced and released by your body after eating. This helps to control your blood sugar level after meals by slowing down the process of food leaving your stomach. Victoza prevents the liver from producing too much glucose, and when blood sugar levels are high, it prompts the pancreas to create more insulin. Diabetes affects your metabolism and causes high blood sugar due to problems associated with using or making insulin in your body.

Victoza is not insulin so it can be taken in combination with long-acting insulin as separate subcutaneous injections. Both drugs can be injected in the same body area (ie. stomach area), however, they should not be injected close together.

Victoza can be taken at any time of the day, once a day, and does not need to be taken at meal time. It should be injected at the same time every day, so it’s best to get into a daily routine. Victoza should be injected under the skin in your upper arm, abdominal area (stomach), or thigh (upper leg), as instructed by your doctor. Victoza should not be injected into a vein or muscle.

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Can Victoza be used for weight loss?

Victoza is not meant to be used specifically for weight loss, however, due to the way this drug works, it may assist adults to lose weight. In a clinical trial studying adults with type 2 diabetes mellitus, Victoza was shown to lead to weight loss when combined with metformin. In addition, it is recommended that overweight individuals that are diagnosed with type 2 diabetes should prioritize weight loss as part of their ongoing management of diabetes. The American Diabetes Association recommends weight loss as an important goal for people with type 2 diabetes who are overweight.

In one study, people with obesity and PCOS successfully lost more weight when they took metformin and Victoza, compared to taking either drug by itself. Metformin is a prescription drug that is commonly prescribed for diabetes and PCOS.

Saxenda is another prescription drug that contains the same active ingredient as Victoza and is FDA-approved to be used for weight loss.

What are the most common side effects of Victoza?

The most common side effects of Victoza in adults are:

The following are less common serious side effects of Victoza:

  • pancreatitis (inflammation of the pancreas)
  • low blood sugar (hypoglycemia)
  • higher risk of thyroid tumors
  • severe low blood sugar levels (hypoglycemia)
  • kidney failure (or kidney problems)
  • gallbladder issues
  • severe allergic reactions

Since thyroid tumors (including cancer) are one of the less common but serious side effects of taking Victoza, it is important to be extra vigilant to identify the signs of this cancer. If you notice any hoarseness, swelling, or a lump in your neck, difficulty or trouble swallowing, or experience shortness of breath, you should contact your healthcare provider immediately to obtain medical advice as these are symptoms of thyroid cancer.

Seek emergency medical attention, or call your healthcare professional if you experience an allergic reaction or experience any of these severe side effects when taking Victoza.

What foods should I avoid while on Victoza?

You should follow a healthy well-balanced diabetes diet while taking Victoza as well as regular exercise to help manage your diabetes.

Although you can eat any food while taking Victoza, it is best to avoid food that is less healthy, such as:

  • fast food
  • drinks that are high in sugar
  • processed foods
  • alcohol
  • very salty foods
  • foods that contain higher amounts of trans and saturated fats
  • red and processed meat
  • highly processed carbs like white bread

It is recommended to discuss any foods to avoid and to create a customized diet or meal plan with a registered dietician or your doctor.

What are the best foods to eat with Victoza?

Generally, it is recommended that you follow a healthy diet plan while taking Victoza. This would include foods such as:

  • light foods, that include lots of vegetables and fruits
  • some protein sources such as eggs, fish, meat beans, and non-dairy protein sources
  • rice, potatoes, pasta, bread, and other wholegrain foods
  • some dairy foods
  • reduced amounts of high fat/sugar foods or drinks

Healthy breakfast ideas

  • wholegrain cereal with milk
  • two slices of wholegrain toast with olive oil-based spread
  • natural unsweetened yogurt and fruit
  • two slices of avocado with a hardboiled egg

Healthy lunch ideas

  • a tuna or chicken salad sandwich
  • a small pasta salad
  • soup
  • a piece of tuna or salmon steak and salad

Healthy dinner ideas

  • lasagne and salad
  • roast chicken and vegetables, with or without potatoes
  • beef stir-fry and vegetables, with or without brown rice
  • chicken tortillas and salad
  • salmon and vegetables, with or without noodles
  • curry with chickpeas and brown rice

Who can take Victoza?

Adults and children over the age of 10 can take Victoza to help manage their type 2 diabetes.

Victoza should not be taken if you:

  • are less than 10 years old
  • diagnosed with type 1 diabetes mellitus
  • are already taking another medication that contains liraglutide.
  • if you have an endocrine condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or if you or a family member have ever had MTC.
  • allergic to any of the ingredients in Victoza including liraglutide or have ever had an allergic reaction to any of the ingredients in Victoza
  • are planning to become pregnant or are already pregnant

Before beginning to take Victoza, discuss with your doctor or healthcare professional if you have any medical conditions, including if you:

  • if you have had any health issues with your liver, kidneys, or pancreas
  • are taking other diabetes medications
  • have severe abdominal problems, such as digesting problems, or gastroparesis (slow emptying of your stomach)
  • plan to or are currently breastfeeding
  • plan to or are currently pregnant

Can I take Victoza with other medications?

Caution should be exercised when taking Victoza with oral medications since Victoza can affect the absorption of these medications. Victoza can be used with some other diabetes treatments but should be discussed with your doctor. Also, it is recommended to consult with your doctor about all possible drug interactions with over-the-counter drugs, other prescription medications, herbal products, or supplements, and other medications you are taking to treat diabetes, including insulin or sulfonylureas.

Victoza may cause low blood sugar (hypoglycemia) or high blood pressure (hyperglycemia). If you are taking any blood pressure medications with Victoza, your healthcare provider will likely monitor your blood pressure to make sure that your body is absorbing that medication.

Why is Linzess so expensive?

Linzess is an expensive prescription medication used once daily to help you have more frequent and complete bowel movements, and it also helps relieve belly pain and overall abdominal symptoms.

Americans pay more for prescription drugs than other developed nations. There are a number of reasons why Linzess may be more expensive than other medications. Linzess is a brand-name drug and there are generic alternatives available for this medication.

Learn more about why Linzess is so expensive and what options are available for you to save on this medication.

What is Linzess (linaclotide)?

Linzess is an FDA-approved prescription medication used as a treatment for adults with Irritable Bowel Syndrome with Constipation (IBS-C) or Chronic Idiopathic Constipation (CIC). It’s manufactured by AbbVie and Ironwood Pharmaceuticals.

Linzess is a brand-name drug that contains the active ingredient linaclotide. It is classified as a guanylate cyclase-C agonists drug. It isn’t a laxative. This medication is a once-daily pill that helps to proactively manage symptoms of IBS-C and CIC, including belly pain and abdominal symptoms (including abdominal pain, bloating and discomfort) that are associated with IBS-C. Linzess capsule is available in the strengths 72 mcg, 145 mcg, and 290 mcg.

This medication acts locally in the intestine and works in two ways, by calming pain-sensing nerves, and accelerating bowel movements.

Linzess side effects

The most common side effects of Linzess are:

  • gas
  • stomach-area (abdominal) pain
  • swelling
  • the feeling of fullness or pressure in your abdomen

Linzess can also cause serious side effects, including diarrhea, which often begins within the first 2 weeks of treatment.  You should immediately stop taking this medication and call your healthcare provider right away if you get severe diarrhea while taking this medication.

If you experience any side effects or possible signs of an allergic reaction while taking this medication, speak with your healthcare professional right away. You are also encouraged to report negative side effects to the FDA (U.S. Food and Drug Administration). You should also let your healthcare provider know about all of the other medications, over-the-counter products, and supplements you are taking.

How much does Linzess cost?

According to the manufacturer, the estimated out-of-pocket cost for Linzess without insurance is $490.63 per month (around works $123 per week), which may vary depending on the dosage prescribed by your healthcare provider. This is the average retail price estimated by the manufacturer.

Linzess price can vary depending on your health insurance coverage for this medication. Contact your insurance company or pharmacist to determine if your health insurance plan covers Linzess in its drug formulary as well as the deductibles and copays for this medication.

Each health insurance plan sets its own formulary that specifies which medications are covered. Some health insurance plans may place Linzess on a higher tier that may result in a higher coinsurance or copayment.

According to the manufacturer, depending on your insurance coverage, eligible individuals may pay as little as $30 for a 30-day or 90-day supply when using the Linzess savings card. Around 85% of prescriptions have an out-of-pocket cost ranging from $0-$35 per month. This offer is not valid for those who are paying cash out-of-pocket, and those who are enrolled in Medicare, Medicaid, or any other federal or state healthcare programs.

Medicare Part D enrollees who qualify for the Extra Help program pay between $0-$8 per month. Around 80% of people who don’t qualify for Extra Help should expect to pay in the range of $0-$50 per month for their Linzess prescription.

For Medicaid enrollees, around 90% of prescriptions for Linzess have an estimated out-of-pocket cost between $0-$4 per month.

Why is Linzess so expensive?

There are a few reasons why Linzess is so expensive in the United States:

The generic version of Linzess is not yet available

A generic version of Linzess is not yet available. The earliest possible date a generic version could become available is from 2026, which is when the patents expire. There is a possibility that the patents will be extended subject to possible pediatric extension, which will delay the launch of the first generic alternative of this medication. Until the Linzess patents expire, there will be no generic drug alternatives available for this medication.

Generic drugs typically cost much less money than their brand-name counterparts. The FDA has a rigorous registration process for all pharmaceuticals including generic drugs, that requires them to be “bioequivalent” to the brand-name product, which means that they have the same active ingredient, strength, dosage form, and route of administration.

RELATED: Brand vs generic drugs

Patent law protection

When a new drug is registered for the first time, the pharmaceutical company that discovered the drug is given a patent. This patent protects the company’s investment in the drug by giving them the sole rights to manufacture and sell the drug for a certain number of years.

In the United States, patents for drugs are typically 20 years from the date of filing the application. However, there are a few ways that a drug company can extend its patent protection and delay generic manufacturers from entering the market with lower-cost generic alternatives. One way is through the FDA’s “pediatric extension program.” This program allows drug companies to extend the exclusivity period of their patents by an additional six months if they conduct studies on the safety and efficacy of their drugs in children.

Another way that a company can extend its patent protection is through the “new use” or “new formulation” of its drug. This means that even though the original patent for the drug has expired, the company may still have some form of exclusivity on a new use or formulation of their drug.

This can make it difficult for generic companies to develop and market their own version of the drug, because they may not be able to get FDA approval for their generic version until after the exclusivity period has ended.

Unregulated pharmaceutical prices in the United States

In the United States, there is no regulation of drug prices. This means that pharmaceutical companies can charge whatever price they want for their drugs.

Other countries, such as Canada and the United Kingdom, have government-run healthcare systems that negotiate with pharmaceutical companies to get the best price for their drugs. In contrast, in the United States, each insurance company negotiates its own price with drug companies.

A study by RAND concluded that prescription drug prices in the United States are on average 2.56 times higher than in other OECD countries.

How do I save on Linzess?

Linzess is an expensive prescription drug, especially for people who do not have sufficient insurance coverage for this medication. There are a few options that could possibly help you save money on your Linzess prescription:

  1. Linzess Savings Card – the manufacturer offers a savings card to help eligible individuals pay as little as $30 for a 30-day or 90-day supply when using the Linzess savings card (offer not valid for those who are paying cash out-of-pocket, and those who are enrolled in Medicare, Medicaid, or any other federal or state healthcare programs). Make sure to review the latest terms and conditions on the manufacturer’s website to find the latest eligibility requirements.
  2. Patient assistance programs – find out if you may be eligible for enrollment into the Linzess patient assistance program.
  3. Ask your prescribing doctor for free samples of Linzess – many pharmaceutical companies give free samples to healthcare providers to help their patients get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any lower-cost alternative medications – ask your prescribing doctor if there are any less expensive alternatives to Linzess such as Amitiza (lubiprostone) or its generic alternative.
  5. Shop around for the lowest price at multiple mail-order pharmacies – medication prices vary by pharmacy so it is recommended to always check pricing at multiple pharmacies to find a lower price for your medicine, as your local pharmacy may not be the cheapest option.
  6. Get a 90-day supply – it may be cheaper to purchase a 90-day supply of this medication at a time as there may be volume discounts available at your pharmacy.
  7. Linzess coupons – find out if there is a Linzess manufacturer coupon or discount card available that could help you save money on this medication.
  8. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that covers the cost of Linzess.

Why is Xifaxan so expensive?

Xifaxan is an expensive prescription drug used to treat irritable bowel syndrome with diarrhea (IBS-D) in adults and traveler’s diarrhea. IBS affects around 11% of the global population and only 30% of people who experience symptoms will consult a physician.

Americans pay more for prescription drugs than any other country. There are currently no generic alternatives to Xifaxan. Find out why Xifaxan is so expensive and what options are available to save money on this medication.

What is Xifaxan (rifaximin)?

Xifaxan is an FDA (U.S. Federal and Drug Administration) approved prescription medication used for the treatment of:

  • irritable bowel syndrome with diarrhea (IBS-D) in adults
  • traveler’s diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old
  • hepatic encephalopathy by stopping the growth of bacteria that produce toxins and that could potentially worsen liver disease, and lower the risk of a decline in brain function in adults with liver failure

Xifaxan is also used to relieve bloating from medical conditions such as small intestinal bacterial overgrowth (SIBO). Unlike the large intestine (also known as the gut or colon), which has most of your gut bacteria, the small intestine should not contain large amounts of bacteria.

The active ingredient in Xifaxam is rifaximin. Rifaximin is a gastrointestinal-selective antibiotic with a broad spectrum of antimicrobial activity, minimal drug interactions, an excellent safety profile, and negligible impact on the intestinal microbiome.

This medication comes in tablet form for oral administration in the strengths 200mg and 550mg, and can be taken with or without food. Xifaxan is manufactured by Salix Pharmaceuticals.

Xifaxan side effects

The most common side effects of Xifaxan in clinical trials, when used for the treatment of irritable bowel syndrome with diarrhea (IBS-D), are nausea and an increase in liver enzymes. Constipation was observed in only 0.5% of people taking Xifaxan, and nausea was observed in 3% of people taking Xifaxan vs 2% of people taking a placebo.

Other common side effects of rifaximin include swelling in your hands or feet, headache, dizziness, tiredness, or abnormal liver function tests.

With antibiotics like rifaximin, there is a possibility that you could experience diarrhea caused by an overgrowth of bacteria which may cause symptoms that range in severity from mild diarrhea to life-threatening colitis.

If you experience any side effects or possible signs of an allergic reaction while taking Xifaxan, speak with your healthcare provider right away. You are also encouraged to report negative side effects to the FDA. Let your healthcare provider know about all of the other medications, over-the-counter products, and supplements you are taking. To report the side effects of this medication, visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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How much does Xifaxan cost?

The estimated retail price for Xifaxan without insurance is around $315 for a pack of 30x200mg tablets, and up to around $3,000 for a pack of 60x550mg tablets.

Xifaxan cost can vary based on your health insurance coverage for this medication. Contact your insurance broker or pharmacist to find out if your health insurance plan covers Xifaxan under its formulary. You should also find out from your insurance company if there are any deductibles and the copay amount for this medication.

Each insurance plan has its own drug formulary that determines which drugs it will cover. Some insurance plans may have Xifaxan on a higher tier which means that this prescription drug may have to pay a higher coinsurance or copayment.

According to the manufacturer:

  • 90% of eligible commercially insured individuals who had prescription drug coverage for Xifaxan paid less than $10 out-of-pocket for their prescription when an eVoucher or copay card was used in 2020.
  • 98% of commercially insured individuals have prescription drug coverage for Xifaxan, and more than 70% of these individuals have access to this medication without step therapy.
  • 96% of people enrolled in Medicare have coverage for Xifaxan
  • Low-income subsidy (LIS) enrollees pay no more than $9.20 per Xifaxan prescription, which is a Medicare Part D benefit.

Why is Xifaxan so expensive?

There are a few reasons why Xifaxan is an expensive prescription drug:

The generic version of Xifaxan is not yet available

Generic Xifaxan is not yet available in the United States. The earliest possible date a generic version could become available is sometime in 2027, which is when the patents are expected to expire. Until then, a generic drug alternative will not be available for this medication.

Typically, generic drugs cost less than brand-name drugs as multiple pharmaceutical manufacturers sell the medication at competitive prices. When there is no generic alternative on the market, there is only one manufacturer that sells the drug.

RELATED: Brand vs generic drugs

Patent law protection

Xifaxan is under patent protection by the United States Patent and Trademark Office (USPTO) covering the composition of matter and the use of Xifaxan listed in the approvals granted by the U.S. Food and Drug Administration (FDA). This allows the drug’s manufacturer, Salix Pharmaceuticals, to have exclusive rights to sell Xifaxan. The FDA approval process for a new drug is lengthy and expensive, so pharmaceutical companies typically recoup their research and development costs by charging higher prices for their brand-name drugs.

Typically, most drug patents expire 20 years after the initial application date. For medications that are used in the treatment of rare diseases that affect 200,000 or fewer people in the United States, the Orphan Drug Act provides pharmaceutical companies an additional seven years of patent protection. Pharmaceutical companies can also apply for an extension on the patent protection by reformulating the medication, changing how to drug is administrated, or simplifying the dose, which is commonly known as a “new formulation” or “new use” patent. The extension of the patent will delay the availability of generic alternatives for the medication.

After the patent expires, other drug companies can start applying for FDA approval to market generic alternatives of the medication, which are typically much less expensive than brand-name drugs because the generic manufacturers do not have the same costs associated with bringing a new drug to market. The first generic of Xifaxan could be available as soon as 2027 which is when the patents expire.

Unregulated prescription drug prices in the United States

Unlike most other developed countries, the United States does not have any laws regulating the price of prescription drugs. The pharmaceutical companies are solely responsible for setting the prices of prescription drugs. The cost of prescription drugs is determined by many factors, including:

  • The cost of research and development
  • The price of the raw materials needed to make the medication
  • The demand for the drug
  • Marketing and advertising costs
  • Profit margins
  • The cost of research and development

It typically costs a pharmaceutical company billions of dollars to bring a new drug to market. The cost of research and development is often recouped by charging higher prices for brand-name drugs.

A study by RAND shows that medication prices in the United States are on average 2.56 times higher than in other OECD countries.

How do I save on Xifaxan?

Xifaxan is an expensive drug, especially for those who do not have any prescription drug coverage for this medication. Fortunately, there are several options that could possibly help you save money:

  1. Xifaxan Savings Card – the manufacturer offers a savings card to help save money. If eligible, commercially insured individuals who had coverage for Xifaxan could pay less than $10 for their medication when a copay card or eVoucher is applied.
  2. Patient assistance programs – find out if you are eligible for enrollment into a Xifaxan patient assistance program.
  3. Ask your prescribing doctor for free samples of Xifaxan – many pharmaceutical companies provide healthcare providers with free samples to provide to their patients in order to help them get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative medicines for your medical condition – ask your prescribing doctor if there are any lower-cost alternatives to Xifaxan.
  5. Shop around for the lowest price at multiple mail-order pharmacies – the price for Xifaxan can vary by pharmacy and may not be the cheapest at your local pharmacy, so you should always check pricing at multiple pharmacies to find the lowest possible price.
  6. Xifaxan coupons – find out if there is a Xifaxan manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Xifaxan.

What foods to avoid while on Stelara

Stelara may increase the risk of infections and it’s recommended to avoid uncooked or potentially contaminated foods while on this medication. There are also certain diet recommendations you can follow if you have plaque psoriasis, psoriatic arthritis, Crohn’s disease, or ulcerative colitis. Eating and avoiding certain foods can help with the symptoms of these medical conditions.

What is Stelara (ustekinumab)?

Stelara is a biologic drug that is FDA (U.S. Food and Drug Administration) approved to treat:

  • plaque psoriasis in adults and some children
  • psoriatic arthritis in adults
  • Crohn’s disease in adults
  • ulcerative colitis in adults

This medication belongs to a class of drugs called monoclonal antibodies. Biologics are made from living cells and work by targeting a specific protein involved in the overactive immune response that causes these conditions. It is manufactured by Janssen Biotech, Inc.

Over 425,000 patients in the United States have been treated with Stelara for Crohn’s disease and other medical conditions. Over 100,000 patients in the United States have been treated with Stelara for Crohn’s disease and ulcerative colitis.

The active ingredient in Stelara is ustekinumab, which is a human monoclonal antibody. Ustekinumab works by targeting and binding to two different proteins: interleukin (IL)-12 and IL-23. These are cytokines, which are involved in the overactive immune response that leads to plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. By binding to these proteins, ustekinumab blocks their ability to bind to other cells and reduces the overactive immune response. This leads to a decrease in inflammation and the symptoms of these conditions.

The treatment starts with a one-time intravenous (IV) infusion through a vein in your arm that is administered by a medical professional. After the initial infusion, you will continue receiving the medication as an injection under the skin (subcutaneous injection) every 8 weeks. There are a total of 6 injections that are received during the first year of treatment.

What are the most common side effects of Stelara?

The most common side effects of Stelara include:

  • nasal congestion
  • sore throat
  • runny nose
  • upper respiratory infections
  • fever
  • headache
  • tiredness
  • itching
  • nausea and vomiting
  • redness at the injection site
  • vaginal yeast infections
  • urinary tract infections
  • sinus infection
  • bronchitis
  • diarrhea
  • stomach pain
  • joint pain

Stelara is a prescription drug that affects your immune system and may lower your ability to fight infections that can increase your chances of having serious infections or side effects including certain types of skin cancer (especially for people with risk factors for skin cancer), tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.

Serious allergic reactions can occur while taking Stelara. You should get medical help right away if you have any symptoms of a serious allergic reaction.

This is not a full list of all possible side effects of Stelara. Speak with your doctor about any side effects that you may experience while taking this medication.

What type of foods should I avoid while on Stelara?

Stelara may increase the risk of infections so people who take Stelara may be advised to take certain precautions to protect themselves, such as avoiding uncooked or potentially contaminated foods.  As well, infection with salmonella as a result of eating undercooked meat, poultry and eggs could be more serious for some people that are taking Stelara.

While there are no specific foods that cannot be eaten while on Stelara, there are certain diet recommendations you can follow depending on your medical condition.

If you have any questions about the best diet for your condition, get medical advice from your healthcare professional or speak with a registered dietitian.

Diet recommendations for plaque psoriasis

Plaque psoriasis is an autoimmune disease that causes raised, red, scaly patches on the skin. If you have plaque psoriasis, you may want to avoid certain foods that can worsen your symptoms. Cutting back on these foods can help improve your psoriasis symptoms and overall health.

Foods to avoid with plaque psoriasis

  • Alcohol
  • Dairy
  • Refined carbohydrates (for example white bread, pasta, white rice, pastries, and some breakfast cereals)
  • Saturated fats and trans fats (for example, red meat, fried food, cheese, fast food, margarine, and many other processed snacks)
  • Sugary foods (for example, fruit juices, soda, baked goods, candy, artificial sweeteners such as aspartame, and other sweets that are high in added sugar)
  • High-gluten foods

Best foods to eat with plaque psoriasis

  • Fish, lean protein, or plant-based proteins such as tofu or tempeh
  • Fruits and vegetables
  • Legumes (lentils and beans)
  • Seeds and nuts
  • Olive oil
  • Small amounts of low-fat dairy
  • Whole grains

Diet recommendations for psoriatic arthritis

Psoriatic arthritis is a form of arthritis that affects some people who have psoriasis. If you have psoriatic arthritis, you may want to avoid certain foods that can worsen your symptoms. Some foods can make your psoriatic arthritis symptoms worst.

Foods to avoid with psoriatic arthritis

  • Red meat
  • Dairy (consider eating low-fat dairy in moderation if you do not have an intolerance or allergy, or alternatives such as almond milk, soy milk, coconut milk, hemp milk, or flax milk)
  • Processed foods

Best foods to eat with psoriatic arthritis

  • Fish
  • High-antioxidant fruits and vegetables
  • Seeds and nuts
  • Olive oil
  • Beans
  • High fiber whole grains
  • Nightshade vegetables (for example, eggplant, tomatoes, red bell peppers, and potatoes)

You can also consider any of the following diets:

  • Keto diet
  • Gluten-free diet
  • Paleo diet
  • Mediterranean diet
  • Low-FODMAP diet
  • Leaky gut diet
  • Pagano diet
  • AIP diet
  • DASH diet

Diet recommendations for Crohn’s disease

Chron’s disease is an inflammatory bowel disease that can cause symptoms like abdominal pain, diarrhea, fatigue, and weight loss. Cutting back on certain foods can help improve your Crohn’s disease symptoms and overall health.

It is recommended to eat four to six meals daily, stay hydrated, and drink slowly. Use simple cooking techniques such as boiling, grilling, steaming, and poaching.

Foods to avoid with Crohn’s disease

  • Whole grains (for example, whole-wheat pasta, whole-grain bread, popcorn, and bran)
  • Beans
  • High-fiber fruits and vegetables (especially raw fruits and vegetables including cruciferous vegetables such as broccoli, cauliflower, or anything with a peel)
  • Nuts and seeds
  • Alcohol
  • Caffeine
  • Sugar alcohols (for example, sweeteners used in sugarless gum, candy, and some drinks)
  • High-sugar drinks (for example, fruit juice and soda)
  • Dairy (for example, whole milk, cream cheese, soft cheese, ice cream, and sour cream)
  • Spicy foods (for example, chili powder, spicy curries, and cayenne pepper)
  • Greasy, fried, and fatty foods (for example, sausage, salami, butter, coconut, margarine, and cream)

Best foods to eat with Crohn’s disease

  • Fiber-rich foods such as oat bran, beans, barley, nuts, and whole grains
  • Protein such as lean meats, fish, eggs, nuts, and tofu
  • Fruits and vegetables that you can remove the peel and seeds
  • Calcium-rich foods such as collard greens, yogurt, and kefir
  • Food with probiotics such as yogurt, kimchi, miso, sauerkraut, and tempeh

Diet recommendations for ulcerative colitis

Ulcerative colitis is a type of inflammatory bowel disease that causes intense periods of abdominal discomfort, diarrhea, and a loss of appetite. Eating certain foods and cutting back on certain foods can help improve your ulcerative colitis symptoms and reduce the risk of flares and inflammation.

Foods to avoid with ulcerative colitis

  • Alcohol
  • Caffeine
  • Dairy products
  • Carbonated drinks
  • High-fiber foods (for example, dried beans, fruits, whole grains, berries, peas, and legumes)
  • Popcorn
  • Potatoes
  • Fatty meats
  • Nuts and seeds
  • Sugar alcohols (for example, sweeteners used in sugarless gum, candy, and some drinks)
  • Fructose sugar (for example, high-fructose corn syrup, fruit juice, honey, and molasses)
  • Gluten
  • Spicy foods
  • Raw stringy vegetables (for example, celery and other gas-producing vegetables including cabbage, brussels sprouts, and broccoli)

Best foods to eat with ulcerative colitis

  • Applesauce
  • Salmon
  • Squash
  • Avocados
  • Some fermented foods (for example, yogurts, containing active probiotics)
  • Instant oatmeal with no additional flavoring
  • Refined grains (for example, pasta, bread, and cereal made from refined grains)
  • Eggs

Who can use Stelara?

Stelara is a biologic prescription drug used to treat:

  • adults over 18 years of age and children 6 years of age and older with moderate to severe psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills)
  • adults over 18 years of age with active psoriatic arthritis
  • adults over 18 years of age with moderately to severely active Crohn’s disease
  • adults over 18 years of age with moderately to severely active ulcerative colitis

Only use this medication exactly as prescribed by your doctor. Stelara is intended for use under the guidance and supervision of your healthcare provider.

In children 6 years of age and older, it is recommended that this medication only be administered by a healthcare provider.

Do not inject Stelara on your own unless your healthcare provider decides that you or a caregiver may administer your injections for you at home. You should first receive training on how to prepare and inject Stelaraa.

Your healthcare provider will prescribe the right dose of Stelara for you to take, the amount to be used for each injection, and the frequency for you to receive this medication.

Do not take Stelara if you:

  • have cancer, posterior reversible encephalopathy syndrome (PRES), or lung inflammation
  • have ever had an allergic reaction to Stelara or to any of the active ingredients
  • are allergic to latex (the needle cover on the Stelara prefilled syringe contains latex)
  • have recently received or are planning to receive a vaccine (immunization)
  • have any new or changing lesions within psoriasis areas or on normal skin
  • have received or are receiving any allergy shots
  • have received or are receiving phototherapy for your psoriasis
  • are pregnant or plan to become pregnant as it’s not known if this medication could harm your unborn baby
  • are breastfeeding or plan to breastfeed as the medication passes into your breastmilk

Before starting to take this medication, tell your doctor if you have an infection or symptoms such as:

  • fever, sweats, or chills
  • muscle aches
  • cough
  • shortness of breath
  • blood in phlegm
  • weight loss
  • warm, red, or painful skin or sores on your body
  • stomach pain
  • diarrhea
  • burning when you urinate or urinating more often than usual
  • feeling very tired

You should tell your healthcare provider about all the medications you take, including prescription drugs and over‐the‐counter products, vitamins, and herbal supplements.

Can I take Stelara with other medications?

There are no known interactions between Stelara and other medications. It can be used alone or with methotrexate. However, as with all medications, it is always best to speak with your healthcare provider before starting or stopping any medication.

You cannot receive a live vaccine while taking Stelara. Before taking Stelara, tell your healthcare provider if you have recently received or are planning to receive an immunization (vaccine). As well, tell your healthcare provider if anyone in your house needs a vaccine as the viruses that are used in some types of vaccines could spread to people with a weakened immune system which may cause serious problems. For one year before and after taking Stelara, you should also not receive the BCG vaccine.

Can I take vitamin D with Stelara?

Yes, you can take vitamin D with Stelara. Vitamin D is a nutrient that helps keep your bones healthy and strong. It is important to get enough vitamin D, especially if you have Crohn’s disease or ulcerative colitis, as these conditions can make it difficult to absorb this nutrient from food.

You can get vitamin D from food, such as fatty fish, eggs, and fortified milk. You can also get vitamin D from supplements or exposure to sunlight.

If you have any questions about the best way to get vitamin D, speak with your healthcare provider or registered dietitian.

Insurance and NiceRx

In some cases, insurance doesn’t provide the best deal. This could be due to high copays, high deductibles, or maybe because your prescription drug isn’t covered by your health insurance company’s formulary. You might also be in the ‘donut hole’, the coverage gap that temporarily limits your prescription drug coverage until you have met the minimum out-of-pocket expenses required by your drug plan.

In many cases, getting your medication through NiceRx can actually save you money compared to the high copays or coinsurance charges that are incurred when buying your medication through insurance.  Fortunately, you can get your medications through NiceRx instead of your insurance.  Here is a detailed guide that explains how to determine which option is better for you.

Can I use NiceRx instead of using my insurance?

You can use NiceRx if the price of your medication through your health insurance or Medicare is more than $49 per month. You cannot use NiceRx and insurance at the same time. You can, however, use NiceRx as an alternative to your prescription drug insurance or government-funded programs, including Medicare and Medicaid for accessing your prescription drugs. NiceRx is not insurance or a drug discount card.

To find out if you are eligible for assistance through NiceRx, get started and complete your online enrollment. NiceRx will notify you if you are eligible to receive your medication for $49 per month, with our help.

Our advocates are available to help you if you have any difficulty enrolling online on your own. Contact us if you have any questions.

10 drugs that could be cheaper with NiceRx than your insurance

Drug nameEstimated retail priceEstimated insurance priceNiceRx priceEstimated monthly savings
Ozempic$892$223$49$174
Eliquis$529$132$49$83
Xarelto$550$138$49$89
Januvia$480$120$49$71
Rybelsus$851$213$49$164
Vraylar$1312$328$49$279
Emgality$653$163$49$114
Jardiance$570$143$49$94
Entresto$545$136$49$87
Trelegy Ellipta$620$155$49$106

Note: Estimated insurance prices are calculated based on the manufacturer’s list price or average list retail price, and the maximum copay of 25% of the price of the drug once you reach your coverage gap. Your insurance price may vary depending on the copay or coinsurance set by your insurance company.

How to decide between my insurance and NiceRx?

You can compare prices at home and don’t need to wait until you get to the pharmacy to find out if getting your medication through NiceRx will be cheaper for you. Here’s how:

1. Check the insurance price for your medication

Login to your health insurance company’s online portal and find the “Price a Medication” link that is typically located in your Pharmacy Benefits section. Review any possible restrictions, including prior authorization, quantity limits, or step therapy. Also check if you have a deductible, which requires that you pay the full list price for the medication until you reach the coverage gap (out-of-pocket) limit.

2. Compare your insurance price with NiceRx

NiceRx charges a flat monthly fee of $49 for each eligible medication. If you are eligible for assistance, NiceRx will help you access your medication directly from U.S. pharmaceutical companies.  If your insurance price is higher than $49 per month and you are eligible for assistance, NiceRx may be a better option to help you save money!

3. Choose the best option for you

Depending on what the copay fee or coinsurance percentage charge will be through your insurance company, NiceRx might be the better option for you to save more money.

Why is NiceRx cheaper than my insurance company?

While your health insurance company may help cover your major medical expenses, the cost of healthcare is continually increasing at a rate higher than inflation, and many insurance plans are covering less than they used to.

Insurance companies will use a drug formulary, which is an approved list of drugs that they will cover at tiered prices. If your prescription drug is placed on a higher tier on the insurance company’s formulary, or if it is considered as a non-preferred drug in the formulary, that may result in a higher copay or no coverage.

As well, if your insurance plan has a deductible for prescription drugs, you may be required to pay the full list price for your prescription drug until you reach the coverage gap (out-of-pocket maximum).

If the insurance price for your medication will cost you more than $49 per month, NiceRx may be a better option for you to save money instead of paying for your medication with insurance.

Can I get reimbursed by my insurance company if I use NiceRx?

NiceRx is completely separate from your insurance. When using NiceRx’s service, you are choosing to pay for your medication without insurance. Typically, insurance companies do not reimburse for NiceRx’s service and it’s up to the insurance company to decide if they will reimburse you.

US Workplace Accident Report

How common are workplace accidents in the US? And which states see the most injuries?

No matter how careful you may be, there’s no escaping the risk of having the occasional accident. Usually, these are nothing more serious than stubbing your toe, getting a papercut, or simply spilling your coffee. However, bad things can happen when you least expect them, and nobody is immune to injury.

This made us at NiceRx consider the risk of injury at work, where we spend the majority of our time during the week. Workplaces can come with a whole host of risks that you wouldn’t otherwise encounter in your day-to-day life, and depending on your profession, an accident can be an extremely dangerous proposition.

With this in mind, we wanted to find out where in the US the most people are prone to serious workplace accidents. We’ve looked through official government statistics to identify the country’s top accident hotspots and reveal the people most at risk from a fatal accident at work.

Non-fatal occupational injuries by state

Here we compare the number of non-fatal workplace injuries in each state with their respective civilian labor force to present the number of accidents per 100,000 workers. How high is the rate in your state?

Non-fatal injuries state

 

1. Vermont

Injuries per 100,000 workers: 2,896.54

Vermont has the accident-prone workforce of any state, with as many as 2,896.54 occupational injuries per 100,000 workers. The state is home to large manufacturing and agriculture industries, which could at least in part explain the very high accident rate. After all, it’s probably not entirely down to clumsiness.

2. Maine

Injuries per 100,000 workers: 2811.11

The state with the second highest rate of non-fatal workplace injuries is Maine, where there were 2,811.11 injuries per 100,000 workers. This could make the New England area seem like a particularly dangerous place to work, though no other state in the region has made the top ten.

3. Nevada

Injuries per 100,000 workers: 2308.39

In third place, with 2,308.39 injuries per 100,000 workers, is Nevada. In addition to agriculture and manufacturing, as well as the tourism industry that Nevada is perhaps most famous for, the state is home to a large mining industry, with the notoriously dangerous occupation potentially boosting the number of injuries.

Fatal occupational injuries by state

Unfortunately, not all accidents can be recovered from, and many people lose their lives each year while at work, through no fault of their own. In this section we will compare how the fatal workplace injury rates vary from state to state, and whether the most dangerous areas are the same for fatal and non-fatal accidents.

 

Fatal occupation injuries by state

 

1. Wyoming

Fatal injuries per 100,000 workers: 13

Wyoming is the state where you’re most likely to have a fatal accident at work, with 13 fatalities for every 100,000 workers. While only 31 deaths were recorded across the state, Wyoming’s small population means the rate is actually much higher than it initially seems.

2. Alaska

Fatal injuries per 100,000 workers: 10.7

Alaska has the second highest rate of fatal occupational injuries at 10.7 per 100,000 workers. The rugged terrain, icy conditions and remoteness of much of Alaska brings with it additional risks that could have translated into a higher fatality rate.

3. South Dakota

Fatal injuries per 100,000 workers: 7.8

In third place is South Dakota, which recorded a workplace fatality rate of 7.8 deaths for every 100,000 workers. South Dakota is closely followed by North Dakota, which came fourth with a rate of 7.4, showing that the similarities between the states run much deeper than a shared name.

Fatal injuries by industry

Here we have ranked industries by the number of fatal occupational accidents that took place in each in 2018. As figures for the number of employees in each industry were not available, we have presented the data as a simple number of fatalities, rather than a rate per 100,000 workers.

 

Fatal injuries by industry

 

1. Construction

Fatal Occupational Injuries: 1,008

The construction industry is the most dangerous industry to work in in the United States with a total of 1,008 fatal occupational injuries in a single year. This is the only industry to exceed 1,000 fatalities, with the second most dangerous industry being transportation and warehousing at 874.

Fatal injuries by affected body part

This section examines which parts of the body are most commonly injured in a fatal workplace injury.

 

Fatal injuries by affected body part

 

1. Head 

Fatal Occupational Injuries: 992

The most common body part to be damaged in a fatal occupational injury is the head, with 992 fatalities. This is followed by the trunk, or torso, with 826 fatal injuries, and then by the neck with 248.

Fatal injuries by sex

There is also a big difference in the number of fatal workplace injuries between male and female workers. Men are much more likely to be the victim of a fatal injury at work, accounting for 92.13% of all cases. While men and women do have different habits and may behave differently in certain situations, this huge disparity is likely due to men being more commonly employed in dangerous industries such as construction, mining and commercial fishing.

 

Fatal injuries by sex

Fatal injuries by age

Your age can also have a big impact on how likely you are to sustain a fatal injury in the workplace. Here’s how different age brackets compare for their total number of fatal occupational injuries.

 

Fatal injuries by age

 

1. 45 to 54 years

Percent of Occupational Injuries: 21.22%

The most common age range for occupational injuries is people between the age of 45 and 54, accounting for 21.22% of all instances. This is closely followed by 55 to 64 year olds with 21.03% of total fatal injuries, suggesting that older workers are much more likely to have a fatal accident than their younger colleagues.

Fatal injuries by day of the week

Here we can see the total number of fatal occupational injuries depending on the day of the week, revealing the most dangerous days for workers.

 

Fatal injuries by day of week

 

1. Thursday

Fatal Occupational Injuries: 922

Thursday is the most dangerous day of the week for fatal occupational injuries with 922 fatalities being recorded. This is closely followed by Wednesday on 906, while Monday and Tuesday are tied for third place on 852. Friday is the weekday with the lowest number of fatalities, while levels drop off significantly at the weekend while fewer people are at work.

Fatal injuries by month

We can also split the data by month, to reveal the time of year when fatal accidents are most likely to occur.

 

Fatal injuries by month

 

1. August

Fatal Occupational Industries: 493

August is the month when workers are most likely to suffer a fatal injury at work, with 493 recorded incidences. This is followed by July on 488, May on 475, and June on 472, indicating that the summer months are the most dangerous time of the year for accidents at work. This could be due to the hot weather making people tired and more clumsy, people being more relaxed and therefore paying less attention, or a combination of both.

Methodology

We wanted to find out where in the USA is the most accident-prone, as well as looking at various other accident trends in the country.

To do this, we used data from the Bureau of Labor Statistics that allowed us to see the breakdown of fatal and non-fatal occupational injuries across different states, as well as splitting the fatal occupational injury data by age, sex, day, month, industry and affected body part. This allowed us to reveal the most dangerous industries to work in, as well as when you’re most likely to sustain an injury and which groups are most at-risk.

Non-fatal injury data was not available for all 50 states, so our ranking for this type of injury does not cover the entire country. The states not included in this section are Colorado, Florida, Idaho, Mississippi, New Hampshire, North Dakota, Oklahoma, Rhode Island and South Dakota. A breakdown of non-fatal injury data by additional factors was also not available.

Why is Trulicity so expensive?

Trulicity is an expensive prescription medication that is proven to lower blood sugar levels. Americans pay more for medications than people in any other country. Learn more about why Trulicity is so expensive and what options are available for you to save on this medication.

What is Trulicity (dulaglutide)?

Trulicity is an FDA-approved prescription medication used to improve glycemic control (blood glucose levels) in adults with type 2 diabetes. It is also used for reducing the risk of major cardiovascular events including death, heart attack, or stroke in people who have heart disease or multiple cardiovascular risk factors. This medication belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 agonists). This medication is not approved for the treatment of type 1 diabetes.

Trulicity is injected once weekly under the skin of your stomach, thigh, or upper arm. Trulicity is manufactured by Eli Lilly USA, LLC and was approved by the FDA in 2014.

RELATED: Trulicity vs Ozempic

Trulicity side effects

The most common side effects of Trulicity are:

  • nausea
  • diarrhea
  • vomiting
  • abdominal pain
  • decreased appetite
  • indigestion
  • fatigue

The most serious side effects of Trulicity are:

  • inflamed pancreas (pancreatitis)
  • low blood sugar (hypoglycemia)
  • acute kidney injury
  • severe stomach problems
  • changes in vision

If you experience any side effects or possible signs of an allergic reaction while taking this medication, speak with your healthcare provider right away. You are also encouraged to report negative side effects to the FDA. Let your healthcare provider know about all of the other medications, over-the-counter products, and supplements you are taking. To report side effects of this medication, visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Get your Trulicity medication for only $49 per month

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How much does Trulicity cost?

The estimated out-of-pocket cost for Trulicity without insurance is $886.36 per month (around works $222 per week), which can vary based on the dose prescribed by your healthcare provider. This is the list price estimated by the manufacturer.

Trulicity prices can vary based on your health insurance coverage and your insurance company plan’s coverage for this medication. Contact your insurance broker or pharmacist to find out if your health insurance plan covers Trulicity under its formulary.

Each Medicare plan has its own formulary and will determine how much it will cover for each medication. Some insurance plans can place Trulicity on a higher tier which means that this medication will have to pay a higher coinsurance or copayment. Other insurance plans can exempt Trulicity from the annual deductible amount as well.

According to the manufacturer, around 70% of people who have prescription drug coverage through Medicare (including Medicare Part D and Medicare Advantage) pay between $0-100 per month, and the remaining people pay an average of $207 per month.

RELATED: How much does Trulicity cost without insurance?, How much does Trulicity cost with Medicare?

Why is Trulicity so expensive?

There are a few reasons why Trulicity is so expensive in the United States:

Generic version of Trulicity is not available

A generic version of Trulicity is not yet available. The earliest possible date a generic version could become available is from 2027-2029, when the patents expire. Until then, there will be no generic drug alternatives available for this medication. Typically, generic drugs cost less than brand-name drugs.

The high cost of brand-name Trulicity is due to the expensive research and development costs associated with bringing a new medication to market. Drug companies often charge high prices for new medications to recoup these costs.

RELATED: Brand vs generic drugs

Patent law protection

Brand-name prescription drug costs are also very expensive in the United States due to the patent laws that prevent generic drugs from being marketed until the brand-name drug’s patent expires, which is generally 20 years after the initial application date. The patents for Trulicity will expire around 2027-2029.

When a pharmaceutical company discovers a new drug and introduces it to the market for the first time, the company is given an exclusive right to market that drug by the United States Patent and Trademark Office (USPTO). The patent protection period is intended to allow the pharmaceutical company to recoup its investment in researching, developing and marketing the drug for the first time. Pharmaceutical companies often spend billions of dollars on marketing and advertising their drugs each year. This is one reason why brand-name drugs are often more expensive than generic drugs.

After the patent expires, other drug companies are then able to market generic versions of the drug. Generic drugs are typically much less expensive than brand-name drugs because the generic manufacturers do not have the same costs associated with bringing a new drug to market.

Unregulated pharmaceutical prices in the United States

Prescription drug prices aren’t regulated in the United States. This means that drug companies can charge whatever price the market will bear. In contrast, many other developed countries have some form of price controls on pharmaceuticals.

For example, in Europe, most countries have some type of price regulation, whether it’s through government negotiations with drug companies or through reference pricing, where the government sets a maximum reimbursement price for a group of similar drugs.

In the United States, drug companies are free to set their own prices, and they often do so based on what the market will bear. This is one of the reasons why prescription drugs are so much more expensive in the United States than in other developed countries.

A study by RAND shows that medication prices in the United States are on average 2.56 times higher than in other OECD countries.

How do I save on Trulicity?

Trulicity is an expensive diabetes medication, especially for those who do not have prescription drug coverage for this medication. Fortunately, there are a few options that could possibly help you save money on your Trulicity prescription:

  1. Trulicity Savings Card – the manufacturer offers a savings card to help save money. If eligible, you can pay as low as $25 for 12 Trulicity pens. Make sure to review the latest terms and conditions on the manufacturer’s website to find the latest eligibility requirements.
  2. Patient assistance programs – find out if you are eligible for enrollment into a Trulicity patient assistance program.
  3. Ask your prescribing doctor for free samples of Trulicity – many pharmaceutical companies provide healthcare providers with free samples to provide to their patients in order to help them get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative medicines for your medical condition – ask your prescribing doctor if there are any less expensive alternatives to Trulicity.
  5. Shop around for the lowest price at multiple mail-order pharmacies – medication prices vary by pharmacy so it is recommended to always check pricing at multiple pharmacies to find the lowest possible price for your medicine.
  6. Trulicity coupons – find out if there is a Trulicity manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Trulicity.

Why is Pennsaid so expensive?

Americans pay the highest prices in the world for brand-name prescription drugs. Pennsaid is an expensive topical non-steroidal anti-inflammatory drug used for the treatment of osteoarthritis. There’s no generic version of Pennsaid available at this time. Learn more about why Pennsaid is so expensive and what options are available for you to save on this medication.

What is Pennsaid (diclofenac sodium topical solution)?

Pennsaid is an FDA-approved nonsteroidal anti-inflammatory (NSAID) prescription drug that is applied to the skin and is used for treating the pain of osteoarthritis of the knee(s). It is a topical solution that is to be applied to the skin over the affected area.

Pennsaid 2% contains the active ingredient diclofenac sodium topical solution and works by reducing the pain, swelling, and inflammation in the joints.

Pennsaid is usually applied 2 times a day, morning and evening.

Pennsaid side effects

The most common side effects of Pennsaid are application site reactions such as:

  • dryness
  • peeling
  • redness
  • itching
  • pain
  • skin hardening
  • rash
  • blisters
  • scabbing.

Other side effects are:

  • bladder infection
  • bruising
  • sinus congestion
  • nausea
  • upset stomach
  • stomach pain
  • gas
  • constipation
  • diarrhea

The most serious side effects of Pennsaid are:

  • swelling of the throat or face
  • difficulty breathing
  • shortness of breath
  • chest pain
  • weakness in one part of your body
  • upset stomach
  • slurring of speech
  • upper stomach pain
  • black or tarry stools
  • vomiting of blood
  • nausea
  • tiredness
  • weakness
  • itching or yellowing of the eyes or skin
  • unexplained weight gain
  • swelling of legs, arms, feet or hands
  • rash

If you experience any side effects or possible signs of an allergic reaction while taking this medication, speak with your healthcare provider right away. You are also encouraged to report negative side effects to the FDA. Make sure to let your healthcare provider know about all of the other medications, over-the-counter products, and supplements you are taking. To report the side effects of this medication, visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How much does Pennsaid cost?

The cost of Pennsaid varies depending on your health insurance coverage and your insurance plan’s coverage for this medication. Contact your insurance broker or pharmacist to find out if your health insurance plan covers Pennsaid under its formulary.

For individuals who do not have prescription drug coverage for this medication, Pennsaid costs around $2,628.75 per month.

For those with commercial prescription drug coverage (for example, through an employer or private plan), the actual cost or co-pay will depend on your insurance plan’s drug coverage. Each insurance plan is different and your out-of-pocket cost for this medication may vary by plan.

The manufacturer states on its website that commercially insured patients will pay $0 for approved prescriptions. Some patients may have to pay a low copay if the prescription is not covered by their insurance plan.

Why is Pennsaid so expensive?

There are several reasons why Pennsaid and other brand-name medications are so expensive in the United States:

Generic version of Pennsaid is not yet available

A generic version of Pennsaid is not yet available. When a brand-name drug has no generic version, the brand-name drug usually costs more. Generic drugs typically cost a lot less money than their brand-name counterparts as generic pharmaceutical companies do not need to invest in the research and development (R&D) and marketing costs to bring the drug to market.

The patents for Pennsaid are expected to expire on October 17, 2027, which is the earliest possible date that a generic version of Pennsaid may be approved by the FDA for sale. Until then, people will need to purchase the brand-name version of Pennsaid.

RELATED: Brand vs generic drugs

Patent law protection

Another reason why the price of Pennsaid is so expensive is because patent law protection provides the manufacturer of Pennsaid with exclusive rights to sell this drug until the patents expire. Typically, the patent will last for around 20 years from the date of the initial application. When a pharmaceutical company discovers a new drug and introduces it to the market for the first time, that company is given an exclusive patent for that drug by the United States Patent and Trademark Office (USPTO). The patent protection period is intended to allow the pharmaceutical company to recoup its investment in researching, developing and marketing the drug for the first time.

The patents for Pennsaid are expected to expire October 17, 2027 which is the earliest date another pharmaceutical company can apply for authorization from the FDA to market a generic alternative of Pennsaid.

Unregulated pharmaceutical prices in the United States

Americans are paying the highest prices in the world for brand-name medications. In contrast to other developed nations, the United States does not regulate the prices of prescription drugs. The prices of medications continue to increase at a rate that is faster than inflation, according to a study conducted by AARP.

Another study conducted by RAND concluded that medication prices in the United States are on average 2.56 times higher than in other OECD countries.

How do I save on Pennsaid?

Pennsaid is an expensive NSAID brand-name medication, especially for those who do not have prescription drug coverage for this medication. Fortunately, there are a few options that be could help you save money on Pennsaid:

  1. Pennsaid Copay Card – the manufacturer offers a copay card to help save money. Those who qualify will pay as little as $0 per month for Pennsaid. Make sure to review the latest terms and conditions on the manufacturer’s website to find the latest eligibility requirements.
  2. Patient assistance programs – find out if you are eligible for enrollment into a patient assistance program for Pennsaid.
  3. Ask your prescribing doctor for free Pennsaid samples – most pharmaceutical companies will give free medication samples to healthcare providers to help their patients get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative medicines for your medical condition – ask your prescribing doctor if there are any less expensive alternatives to Pennsaid, such as Vimovo, ibuprofen, meloxicam or naproxen.
  5. Shop around for the lowest price at multiple mail-order pharmacies – medication prices vary by pharmacy so it is recommended to always check pricing at multiple pharmacies to find the lowest possible price for your medicine.
  6. Pennsaid coupons – find out if there is a Pennsaid manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Pennsaid.

What foods to avoid while taking Xifaxan

Xifaxan is an antibacterial prescription drug recommended by the American College of Gastroenterology. It’s the most popular medication used for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

While there are no specific foods that you must avoid while taking Xifaxan, there are certain recommendations you can follow that are suggested for people with irritable bowel syndrome (IBS) and traveler’s diarrhea.

Digestion and food triggers are different from person to person. Some people with IBS can tolerate some foods that others cannot. It’s recommended to get to know your body and learn which foods make you feel good and limit the foods that cause uncomfortable symptoms. You may consider keeping a food and symptom diary to help you identify which foods you should be eating and avoiding.

What is Xifaxan (rifaximin)?

Xifaxan is an FDA-approved prescription drug manufactured by Salix Pharmaceuticals and is used for the treatment of the following medical conditions:

  • irritable bowel syndrome with diarrhea (IBS-D) in adults
  • traveler’s diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old
  • hepatic encephalopathy by stopping the growth of bacteria that produce toxins and that could potentially worsen liver disease, and lower the risk of a decline in brain function in adults with liver failure

The active ingredient in Xifaxam is rifaximin. Rifaximin is in a class of drugs called antibiotics (antibacterial medications) that fights bacteria in the intestines. It comes in tablet form for oral administration and can be taken with or without food.

Xifaxan requires adherence to the prescribed dosing schedule. Missing doses of this medication will not only reduce the effectiveness of the antibiotic treatment but will also increase the risk of bacteria becoming resistant to drug treatment. If a dose of this medication is missed, take it as soon as possible. Do not take two doses at the same time. If it is near the time of the next dose, skip the missed dose.

Xifaxan can also be used to relieve bloating from health conditions such as small intestinal bacterial overgrowth (SIBO). Unlike the large intestine (also known as the colon or gut), which has most of your gut bacteria, the small intestine should not contain large amounts of bacteria.

What are the most common side effects of Xifaxan?

The most common side effects of Xifaxan in clinical trials, when used for the treatment of IBS-D, are nausea and an increase in liver enzymes. Constipation was only observed in around 0.5% of people who took Xifaxan.

Other common side effects of Xarelto include swelling in your hands or feet, dizziness, headache, tiredness, or abnormal liver function tests.

Xifaxan may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) as a result of a type of resistant bacteria.

With antibiotics like Xifaxan, there is a chance you could experience diarrhea caused by an overgrowth of bacteria that may cause symptoms that range in severity from mild diarrhea to life-threatening colitis.

If you have very watery diarrhea several times a day, cramping, bad stomach pains, fast heart rate, fever, nausea, or blood in your stool, call your healthcare provider right away.

If you experience any of these side effects or experience an allergic reaction when taking Xifaxan, call your healthcare professional or seek emergency medical attention right away.

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What foods should I avoid while on Xifaxan?

While there are no specific foods that you cannot eat while taking Xifaxan, people with IBS are advised to avoid:

  • Insoluble fiber, such as whole grains, vegetables and some fruit (apples, cherries, pears and peaches)
  • Gluten, such as rye, wheat and barley
  • Dairy products, such as milk, yogurt and ice ream
  • Fried foods
  • Beans and legumes
  • Caffeinated drinks, such as coffee, sodas, and energy drinks
  • Processed foods, such as chips, premade frozen meals, deep-fried foods and processed meats
  • Sugar-free sweeteners, which are commonly included in sugarless candy, gum, mouthwash and diet drinks
  • Wheat-based products such as cereal, bread and crackers
  • Chocolate
  • Alcohol
  • Garlic and onions
  • Broccoli and cauliflower

People with traveler’s diarrhea are advised not to eat:

  • Unpeeled or unwashed fruits and vegetables
  • Raw leafy vegetables, such as lettuce, spinach and cabbage
  • Raw or rare meats
  • Uncooked or undercooked shellfish

If you have any questions about what foods to avoid while on Xifaxan, get medical advice from your healthcare professional or speak to a dietitian about setting up a diet plan that is right for you.

What are the best foods to eat with Xifaxan?

While there are no specific foods that you need to eat with Xifaxan, people with IBS and SIBO are recommended to follow a low FODMAP diet that includes:

  • Eggs and meat
  • Fish
  • Certain cheeses such as brie, cheddar and feta
  • Almond milk
  • Grains like rice, oats, cornmeal and quinoa
  • Vegetables like eggplant, tomatoes, potatoes, cucumbers and zucchini
  • Fruits such as oranges, grapes, bananas, blueberries, kiwi, strawberries, and pineapple
  • Firm and medium tofu
  • Pumpkin seeds, sunflower seeds and sesame seeds

In general, any foods that don’t contain carbohydrates (carbs) or are low in FODMAPS are suggested in this diet.

Who can take Xifaxan?

Do not take Xifaxan if you are allergic to rifaximin, any of the rifamycin antimicrobial agents, any of the components in Xifaxan, or medications such as rifabutin (Mycobutin), rifampin (Rifater, Rifadin, Rifamate), or rifapentine (Priftin).

Before you take Xifaxan, tell your doctor if you have severe liver disease, diarrhea with fever, or diarrhea that is watery or has blood in it.

If you are pregnant or planning on becoming pregnant, or breastfeeding, speak with your healthcare provider before taking Xifaxan as the medication may cause harm to a nursing infant or unborn baby.

Speak with your healthcare provider before taking this medication if you have a severe hepatic (liver) impairment, as this may cause increased effects of the medicine.

Can I take Xifaxan with other medications?

Tell your doctor if you are currently taking any medications called P-glycoprotein and/or OATPs inhibitors (such as cyclosporine) because taking these drugs with Xifaxan could lead to an increased amount of Xifaxan absorbed by your body.

Xifaxan can also affect warfarin activity when taken together. Tell your doctor if you are taking warfarin as well, because the prescribed dose of warfarin may need to be adjusted in order to maintain the correct blood-thinning effect.

Speak with your doctor about any possible drug interactions with Xifaxan and the other medications, over-the-counter products, supplements and herbal products you are taking.

The treatment with Xifaxan followed by probiotics has shown to reduce the urinary and gastrointestinal symptoms with good compliance.

Alternative Health 2022

The most popular alternative medicines & therapies revealed & the states using them

America is a vastly diverse country, filled with different cultures and races among its people, in fact, the people indigenous to the land of America have always practiced natural medicine – using herbs and plants to heal ailments, definitely different from our prescription medication. However, now there are countless others, a vast array of Asian alternative medical practices and techniques, and even chiropractic medicine, originating in North America.

You might be wondering, which forms of alternative medicine are the most popular across the United States and which of its states are using them the most? Well, we at NiceRx have got you covered, as our research using Google search data uncovers just that!

The most popular forms of alternative medicines and therapies in the US

Most popular alternative medicines

1. Chiropractic

Annual Number of Google Searches: 9,400,000

The most popular alternative medicine in the United States is chiropractic, with 9.4 million annual Google searches. Chiropractic medicine had its origin in North America, in 1895 a Canadian named Daniel David Palmer performed the first chiropractic adjustment, and then went on to found The Palmer School of Chiropractic, located in Iowa, in 1897. A natural form of hands-on care, there is no reason the FDA would approve it, yet it is used all across the USA.

2. Acupuncture

Annual Number of Google Searches: 3,884,000

With less than half the amount of searches that chiropractic managed, we have acupuncture. This practice is an ancient form of Chinese medicine, in fact, it dates to before 2500 BC, and is used to cure disease, ease pain and improve general health. Despite it involving many needles being inserted into your skin, it’s used all over the world.

3. Gua Sha

Annual Number of Google Searches: 3,352,000

With 3.3 million annual Google searches, we have the gua sha, another form of ancient Chinese medicine and more recently a skincare trend. However, its origins date back to the Paleolithic Age and it was scientifically logged as a treatment in medical records dating back to the Ming Dynasty in China. It was used on coma patients to massage their bodies to alleviate their symptoms and to massage against people’s skin to help with the pain.

4. Fasting

Annual Number of Google Searches: 3,239,000

Next up is fasting, which most of you probably have identified as nothing other than a dieting trend or have associated with Ramadan. However, it has been used as a therapeutic treatment as far back as Ancient Greece, when a physician named Hippocrates advised patients to not eat or drink when showing certain symptoms, as that would only feed the illness.

5. Chakra

Annual Number of Google Searches: 3,017,000

And finally, there are chakras, of which the body has seven, and no, this isn’t just a thing from Avatar: The Last Airbender. The concept of chakras arose in early Hindu texts, citing that the body had seven, whereas Buddhist texts contradict this by citing the body has five. It is generally thought that keeping your chakra aligned with meditative practices encourages improved health. The Western take on this, from a variety of people, is that the chakras are all associated with a nerve plexus.

 

Most popular alternative medicines in us

The US states using alternative medicines and therapies the most

Most popular alternate health states

1. Hawaii

Annual Google Searches per 10,000 people: 1,925

Hawaii comes out on top as the state in which alternative medicine is most popular, with 1,925 searches per 10,000 people. The three most searched medical practices from our list of 100 were chiropractic, Thai massage therapy, and acupuncture.

2. California

Annual Google Searches per 10,000 people: 1,919

According to the census data, California is the most populous state in the USA, so it’s no surprise it ranks second here, with 1,919 searches per 10,000 people. The top three most popular searches in California were chiropractic, acupuncture, and the gua sha – with Thai massage and fasting not too far behind.

3. Washington

Annual Google Searches per 10,000 people: 1,886

Third, we have the Northwestern state of Washington, with 1,886 annual searches per 10,000 people. Just as with two prior states, the most searched practice was chiropractic, with acupuncture second, then a tie between gua sha, fasting, and chakra.

4. Oregon

Annual Google Searches per 10,000 people: 1,869

Oregon managed 1,869 annual Google searches per 10,000 people, for a variety of different alternative medicines. Once again, the most popularly searched was chiropractic, with gua sha, acupuncture, fasting, and chakra making up the other most searched alternative medicine for this US state.

5. Colorado

Annual Google Searches per 10,000 people: 1,863

And finally, we have Colorado, one of the Mountain States, with 1,863 annual Google searches per 10,000 people for various alternative medicines. It comes as no surprise to say again, that the most popularly searched alternative medicine for Colorado was chiropractic. With, again, acupuncture and gua sha taking the second and third spots.

 

US states using the most alternative medicines

Methodology

We took a list of alternative medicines from Wikipedia, and then trimmed it down to the top 100 most popularly searched worldwide.

We then used Google Keyword Planner to get search volumes for the entirety of the USA, dating from May 2021 to April 2022 for the 100 alternative medicine to determine which one was the most popular.

Again, using Wikipedia, we took down a list of the US states and their populations, then using Keyword Planner we got search volumes for each state – again from May 2021 to April 2022. We then calculated the searches per 10,000 people, using the population numbers, which were 2019 estimates from the US census.

If you are unable to afford your medication, we may be able to assist. NiceRx provides access to FDA-approved brand-name medications, including Januvia, Motegrity, Aubagio, Breo Ellipta, and Trelegy Ellipta.

Why is Jardiance so expensive?

The costs of prescription drugs in the United States are the highest in the world. The high cost of diabetes drugs is a concern for millions of people. An estimated 9.3% of the US population (29.1 million people) are affected by diabetes, and approximately 37% of all US adults have prediabetes, a condition that greatly increases the risk of developing diabetes.

Jardiance is an expensive diabetes medication with no generic alternative available. Learn more about why Jardiance is so expensive and what you can do to save money when purchasing this medication, with or without insurance.

What is Jardiance (empagliflozin)?

Jardiance is an FDA-approved prescription medication that is used to:

  • lower blood sugar levels in conjunction with exercise and diet in adults with type 2 diabetes
  • reduce the risk of cardiovascular death in adults with type 2 diabetes who also have a known cardiovascular disease
  • reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure, when the heart is unable to pump enough blood to the rest of the body

This medication is not used for the treatment of type 1 diabetes or for lowering blood sugar in adults with type 2 diabetes who have severe kidney problems.

Jardiance contains the active ingredient empagliflozin and belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by blocking the reabsorption of blood sugar (glucose) by the kidneys, increasing glucose excretion in urine, and lowering blood sugar levels in individuals with diabetes. It is manufactured by Boehringer Ingelheim Pharmaceuticals and Lilly.

Jardiance was approved by the FDA on October 14, 2014 and is available as a tablet in the strengths 5 mg and 10 mg. The usual starting dose is 10mg. Swallow the tablets whole with water and do not chew the tablets.

Jardiance side effects

The most common side effects of Jardiance are urinary tract infections and yeast infections in females.

The most serious side effects of Jardiance are:

  • ketoacidosis (increased ketones in your blood or urine)
  • dehydration
  • serious urinary tract infections
  • low blood sugar (hypoglycemia)
  • necrotizing fasciitis
  • vaginal yeast infection
  • yeast infection of the penis
  • allergic (hypersensitivity) reactions

If you experience any side effects or possible signs of an allergic reaction while taking this medication, speak with your healthcare provider right away. You are also encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How much does Jardiance cost?

The cost of Jardiance varies depending on your health insurance coverage and your insurance plan’s coverage for this medication. Speak with your insurance broker or pharmacist to find out if your health insurance plan covers this medication under its formulary.

For individuals who do not have prescription drug coverage for this medication, Jardiance costs around $570.48 per month, according to the manufacturer.

For those with private prescription drug coverage (eg. commercial insurance through an employer or private plan), the actual cost or co-pay will depend on your insurance plan’s drug coverage. Each insurance plan is different and will determine your out-of-pocket cost for this medication. On average, 90% of people with private insurance coverage will pay between $0–$40 per month for Jardiance, and the remaining 10% will pay $227 per month on average. You could pay as little as $0 per month with the Jardiance Savings card, if eligible.

Around 63% of people with Medicare Part D coverage will pay between $0–$50 a month for Jardiance, with the remaining 37% will be around $161 per month. The out-of-pocket costs could vary throughout the year depending on whether or not you have reached your plan’s deductible amount (‘donut hole’). Medicare Part D enrollees may also qualify for the Extra Help program, and the average cost for Jardiance is between $4 and $10 a month when enrolled in Extra Help.

Medicaid enrollees have estimated co-pay costs between $0 to $10 per month, on average.

For those with TRICARE prescription drug coverage, the co-pay will vary depending on where the medication is dispensed. If the medication is dispensed at a military hospital, the co-pay will be $0. If dispensed at a retail pharmacy, the co-pay will be $33 for a 30-day supply. If dispensed by mail order, the co-pay will be $29 for a 90-day supply.

Why is Jardiance so expensive?

There are several reasons why Jardiance and other brand-name medications are so expensive in the United States:

Generic Jardiance is not yet available

Jardiance is only available as a brand-name drug and there are currently no generic drug alternatives available in the United States.

The patents for Jardiance are expected to expire on October 14, 2029, which is the earliest possible date that a generic version of Jardiance can be approved by the FDA for sale in the United States. Until then, people who are prescribed Jardiance will need to continue purchasing the brand-name version of this medication.

Generic drugs are generally less expensive than brand-name drugs because generic pharmaceutical companies do not incur the research and development (R&D) and marketing costs that the original proprietor of the drug must invest to develop and bring the drug to market.

RELATED: Brand vs generic drugs

Patent law protection

When a pharmaceutical company first invents and develops a new drug, that company is given an exclusive patent for that drug by the United States Patent and Trademark Office (USPTO). This exclusive patent gives the pharmaceutical company the sole right to sell the drug while it is in effect. The patent protection period is intended to enable the pharmaceutical company to recoup its investment in researching and developing the drug.

The length of time that a patent is in effect varies depending on the type of drug, but it is typically 20 years from the date that the patent application was filed with the USPTO.

Jardiance is protected by U.S. patents that are set to expire on October 14, 2029. After the patents expire, generic pharmaceutical companies will be able to request FDA authorization to register and sell the generic version of Jardiance which will facilitate the lowering of the price of this medication as multiple generic pharmaceutical companies will compete for market share with their own generic version of the drug.

Unregulated prices

Americans are paying the highest brand-name drug prices in the world. In contrast to other developed nations, the U.S. government does not regulate the prices of prescription drugs. As the patent provides a 20-year monopoly to the proprietor of the drug, it is common for the price of the medication to continually increase before the expiration of the patent.

To provide further insight into the high cost of pharmaceuticals in the U.S., RAND concluded a study that showed that medication prices in the U.S. are on average 2.56 times higher than in other OECD countries. Furthermore, AARP conducted a study that concluded that prescription drug price increases continue to outpace the rate of inflation.

How do I save on Jardiance?

Jardiance is an expensive brand-name medication, especially for those who do not have prescription drug coverage or have high copays for this medication. Fortunately, there are a few options that be able to help you save money on Jardiance:

  1. Jardiance Savings Card – the manufacturer offers a savings card to help save money. Those who qualify will pay as little as $10 per month for a 1-month to a 3-month supply. Make sure to review the latest terms and conditions on the manufacturer’s website to find the latest eligibility requirements.
  2. Patient assistance programs – find out if you are eligible for enrollment into a patient assistance program for Jardiance.
  3. Ask your prescribing doctor for free Jardiance samples – most pharmaceutical companies will give free medication samples to healthcare providers to help their patients get started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative medicines for your medical condition – ask your prescribing doctor if there are any less expensive alternatives to Jardiance.
  5. Shop around for the lowest price at multiple mail-order pharmacies – medication prices vary by pharmacy so it is recommended to always check pricing at multiple pharmacies to find the lowest possible Jardiance price.
  6. Jardiance coupons – find out if there is a Jardiance manufacturer coupon that can help you save money on this medication.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that covers the cost of Jardiance.

Why is Vraylar so expensive?

It’s unfortunate that Americans are paying the highest prices in the world for prescription drugs. Vraylar is an expensive brand-name medication used to treat certain medical health conditions. Find out why Vraylar is so expensive and what options are available to save on this medication.

What is Vraylar (cariprazine)?

Vraylar is an FDA-approved brand-name atypical antipsychotic medication used by adults to treat certain mental health conditions including:

Vraylar is available as a capsule in strengths of 1.5 mg, 3 mg, 4.5 mg and 6 mg. It is manufactured by Abbvie and Allergan, and was approved by the FDA on September 17, 2015. The capsules should be swallowed whole with or without food at around the same time each day.

How does Vraylar work?

Vraylar contains the active ingredient cariprazine. Although the exact mechanism of action is not known for sure, it is thought to affect the activity of two brain chemicals, dopamine and serotonin, which are both chemicals in the brain that are responsible for regulating your mood, behaviors and thoughts.

Vraylar side effects

The most common side effects of Vraylar are:

  • difficulty moving or slow movements
  • tremors
  • restlessness and feeling like you need to move around
  • uncontrolled body movements
  • vomiting
  • nausea
  • sleepiness
  • indigestion

The most serious side effects of Vraylar are:

  • stroke (cerebrovascular problems) in elderly people with dementia-related psychosis that can lead to death
  • neuroleptic malignant syndrome (NMS) – symptoms may include high fever, stiff muscles, increased sweating, confusion, or changes in breathing, blood pressure, and heart rate.
  • uncontrolled body movements (tardive dyskinesia or TD):
  • problems with your metabolism, such as high blood sugar and diabetes
  • increased fat levels (cholesterol and triglycerides) in your blood
  • weight gain
  • low white blood cell count
  • decreased blood pressure (orthostatic hypotension)
  • falls as a result of dizziness or sleepiness
  • seizures (convulsions)
  • impaired judgment, thinking, and motor skills
  • increased body temperature:
  • difficulty swallowing that can cause liquid or food to get into your lungs

Antidepressants may increase suicidal thoughts or actions in some children and young adults within the first few months of taking Vraylar and when the dose of this medication is changed.

If you experience any side effects or possible signs of an allergic reaction while taking this medication, speak with your healthcare provider right away. You are also encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How much does Vraylar cost?

The cost of Vraylar will depend on your health insurance coverage and your insurance plan’s coverage for this medication. Check your health insurance plan to find out what you will pay for this medication if you are currently insured with prescription drug coverage.

For individuals without prescription drug insurance, Vraylar costs around $1,312 per month according to the manufacturer.

For those with private prescription drug coverage (eg. commercial coverage), the average monthly copay can vary by insurance plan.

New eligible individuals may pay as low as $0 for their first 30-day supply prescription and as low as $5 for a 30-day or 90-day supply refill prescription with the Vraylar savings card.

The manufacturer estimates that around 85% of all prescriptions for Vraylar have out-of-pocket costs of around $0-25 per month, including the use of Vraylar savings cards.

Most individuals with Medicare Part D coverage who qualify for the Extra Help program pay between $0-4 per month, and around 80% of those who don’t qualify for Extra Help pay between $0-45 per month.

For Medicaid enrollees, around 90% of prescriptions for Vraylar have an out-of-pocket cost of around $0-$4 per month.

Why is Vraylar so expensive?

There are a few reasons why Vraylar is so expensive in the United States:

Generic Vraylar is not yet available

Vraylar is an expensive brand-name medication with no generic alternatives available.

The patents for this medication are expected to expire on September 17, 2029, which is the earliest possible date that a generic pharmaceutical company can apply for authorization from the FDA to register the first generic alternative for Vraylar. Once the generic drug is available for sale, people who are taking this medication can expect to start paying a lower price.

Generic drugs are often much less expensive than brand-name drugs and are chemically equivalent to their brand-name counterparts. There are many reasons why brand-name drugs cost more than generics, including:

  • The high cost of research and development for new medications
  • The time it takes to bring a new medication to market
  • The costs associated with advertising and marketing the drug to doctors and consumers
  • Patent protection prevents other pharmaceutical companies from selling the same medication

RELATED: Brand vs generic drugs

Patent law protection

Patent laws provide pharmaceutical companies with exclusive rights to market and sell their medication from the time the drug is first approved which generally lasts for 20 years. The patent protection period allows pharmaceutical companies to recoup the large investment which was made into the research and development (R&D) that was required to develop and introduce the new medication to the market which is a costly process. This is intended to incentivize further development of new drugs.

After the patents expire, generic pharmaceutical companies can apply for authorization from the FDA to start selling a generic version of the same drug. As multiple generic companies will eventually sell and compete for the same drug, the price will eventually come down for consumers, making the medication more affordable.

The patents for Vraylar will expire on September 17, 2029, which is the earliest date that a generic drug company will be able to apply for FDA approval to sell a generic version of Vraylar.

Unregulated prices

The prices of prescription drugs in the United States are the highest in the world. Prices are not regulated by the government like in most other countries which creates a free market for pharmaceutical companies to determine the pricing based on the demand for their medications. As patent laws provide a 20-year monopoly to the drug company that initially developed the drug, it is common for the medication price to continue increasing without any competition.

RAND conducted a study that shows that pharmaceutical prices in the United States are on average 2.56 times higher than in other OECD countries, and another study by AARP shows that prescription drug pricing increases continue to outpace the rate of inflation.

How do I save on Vraylar?

Vraylar is an expensive brand-name medication, especially for individuals who are uninsured or with high copays. There are a few options worth considering that may be able to help you save money on Vraylar:

  1. Vraylar Savings Card – Abbvie offers a savings card and eligible individuals may pay $0 for their first two 30-day supply prescriptions and as low as $5 for 30-day or 90-day supply refills. Make sure to review the latest terms and conditions on Abbvie’s website to find the latest eligibility requirements.
  2. Patient assistance programs – find out if you are eligible for enrollment into a patient assistance program for Vraylar.
  3. Ask your prescribing doctor for free Vraylar samples – most pharmaceutical manufacturers give free samples to doctors to provide to their patients in order to assist them with getting started on the medication.
  4. Get medical advice from your healthcare professional and find out if there are any alternative medicines for your medical condition – ask your prescribing doctor if there are any less expensive Vraylar alternatives for the treatment of bipolar disorder or schizophrenia. Alternative atypical antipsychotic medications include Seroquel (quetiapine), Abilify (aripiprazole), Zyprexa (olanzapine), Latuda (lurasidone) and Rexulti (brexpiprazole).
  5. Shop around for the lowest price at multiple mail-order pharmacies – medication prices vary by pharmacy so it is recommended to always check pricing at multiple pharmacies to find the lowest possible price for your medicine.
  6. Vraylar coupons – find out if there is a Vraylar manufacturer coupon that can help you save money.
  7. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of Vraylar.

Why is Vyvanse so expensive?

Americans pay the highest prices in the world for brand-name medications. In 2016, the CDC found that 6.1 million (9.4%) children in the United States have been diagnosed with ADHD. As ADHD is a growing problem, many are concerned about the rising costs of prescription drugs including ADHD medications and are wondering why Vyvanse is so expensive in the United States.

What is Vyvanse (lisdexamfetamine dimesylate)?

Vyvanse is a central nervous system stimulant medication manufactured by Takeda Pharmaceuticals. It is a prescription medication that is used for the treatment of ADHD (attention deficit hyperactivity disorder) in people over the age of 6 and for the treatment of moderate to severe binge eating disorder (B.E.D.) in adults. It is not prescribed for weight loss and it is not known if Vyvanse is effective and safe for obesity.

Vyvanse is a brand-name drug that contains the active ingredient lisdexamfetamine dimesylate. It is available as a capsule and chewable tablet. Lisdexamfetamine is a prodrug of dextroamphetamine, which means it is converted into dextroamphetamine when it enters the body. Dextroamphetamine is a potent central nervous system (CNS) stimulator that belongs to the class of drugs known as amphetamines. It is classified as a Schedule II controlled substance, which means it has a high potential for abuse and dependence.

Vyvanse is a popular medication that is used to treat ADHD and B.E.D. The number of prescriptions for Vyvanse has been steadily increasing over the years as more people are being diagnosed with these disorders.

How does Vyvanse work?

Vyvanse works by increasing the levels of dopamine and norepinephrine in the brain. These neurotransmitters are involved in regulating mood, behavior, and attention.

ADHD is thought to be caused by an imbalance of these neurotransmitters. By increasing the levels of dopamine and norepinephrine, Vyvanse can help to improve symptoms of ADHD.

Vyvanse side effects

The most common side effects of Vyvanse in children between the ages of 6 to 17 and adults with ADHD include:

  • loss of appetite (anorexia)
  • decreased appetite
  • diarrhea
  • dizziness
  • irritability
  • nausea
  • vomiting
  • dry mouth
  • trouble sleeping
  • stomach pain
  • anxiety
  • weight loss

The most common side effects of Vyvanse in adults with moderate to severe B.E.D. include:

  • constipation
  • anxiety
  • dry mouth
  • decreased appetite
  • trouble sleeping
  • increased heart rate
  • feeling jittery

If you experience any side effects or possible signs of an allergic reaction while taking this medication, speak with your healthcare provider right away. You are also encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How much does Vyvanse cost?

Vyvanse cost is around $12.44 per day or $350 for a 30-day supply, for uninsured individuals who need to pay the full retail price out of pocket. This price may vary depending on the pharmacy you purchase the medication from.

The cost of Vyvanse for individuals with prescription drug insurance coverage through Medicare or private insurance will depend on your health insurance plan and the coverage for this drug including the copay and deductible.

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Why is Vyvanse so expensive?

There are several major reasons why this brand-name medication is so expensive:

Patent law protection

The process of developing, testing, and obtaining FDA approval for a new medication is very expensive and can take many years. All brand-name drugs are protected by patents that give the drug company the exclusive right to sell the drug for 20 years.

After the patents expire, other pharmaceutical companies are allowed to sell generic versions of the drug.

The patents for Vyvanse expired in 2023 and generic pharmaceutical companies are now allowed to supply an FDA-approved generic version of Vyvanse.

Unregulated pricing for pharmaceuticals

Prescription drug prices in the United States are the highest in the world. One of the major reasons for this is that the prices of pharmaceuticals are not regulated by the government like they are in most other countries.

The FDA does not have any authority to regulate the prices of drugs in the United States. The cost of a medication is determined by the drug company, which takes into account the cost of research and development, manufacturing, marketing, and distribution.

It is common for drug companies to increase the price of their medications over time, especially if there are no generic alternatives available on the market.

This has been the case with Vyvanse, which has seen several price increases since it was first introduced in 2007.

A study by RAND shows that medication prices in the United States are on average 2.56 times higher than in other OECD countries. Another study by AARP shows that in the United States, prescription drug prices have increased annually more than the rate of inflation.

How do I save on Vyvanse?

The expensive price of Vyvanse can make this prescription drug unaffordable for many people, especially for people who do not have adequate prescription drug insurance. There are several options that may be able to help you save money on this medication:

  1. Vyvanse Savings Card – Takeda provides a savings card to individuals who meet the eligibility requirements that can pay as little as $30 per Vyvanse prescription, up to a maximum savings of up to $60 savings per prescription. This offer covers the amount spent above $30, up to a maximum savings of $60 per prescription. You are responsible to pay for any additional cost over $90 for each prescription. Check the terms and conditions on the Takeda website to determine if you are eligible as this offer may change.
  2. Buy generic Vyvanse – generic Vyvanse is currently available for purchase at a local pharmacy at a significantly lower cost than the brand name medication.
  3. Patient assistance programs – you may be eligible for enrollment into a patient assistance program for Vyvanse.
  4. Ask your doctor if they can provide you with free Vyvanse samples – most pharmaceutical companies provide free samples to doctors that are given to their patients to help them get started on the medication.
  5. Get medical advice from your healthcare professional and find out if there are any alternative medications – ask your prescribing doctor if there are any lower-cost Vyvanse alternatives that can work for you, such as Concerta (methylphenidate), Ritalin (methylphenidate), Adderall XR (amphetamine), or Adderall (amphetamine).
  6. Shop around for the lowest price at mail-order pharmacies – the price of medicines varies by pharmacy so make sure to always check prices at multiple pharmacies to find the lowest possible price for your medication.
  7. Vyvanse coupons – find out if a Vyvanse manufacturer coupon is available that can help you save money on this medication.
  8. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover the cost of your Vyvanse prescription.

Does Ozempic need to be refrigerated?

Ozempic is a brand-name diabetes medication that needs to be stored in the refrigerator between 36°F to 46°F (2°C to 8°C) before the first time you use it. Ozempic is very sensitive to high and low temperatures. Learn more about the storage conditions for Ozempic and how to store Ozempic before and after you start using it.

What is Ozempic (semaglutide)?

Ozempic is a non-insulin injectable medication manufactured by Novo Nordisk and is used to improve blood sugar levels for people with type 2 diabetes. Ozempic is a once-weekly subcutaneous injection that comes in a prefilled pen.

Ozempic is a safe and effective medication when used as directed. When Ozempic is taken weekly as directed by your healthcare provider, along with exercise and diet, it may help to lower blood sugar levels for adults with type 2 diabetes.

The active ingredient of Ozempic is semaglutide. Semaglutide is a glucagon-like peptide-1 (GLP-1 receptor agonist). GLP-1 is a hormone that is released from the gut in response to food. It helps to regulate glucose metabolism by stimulating insulin release from the pancreas and by slowing gastric emptying.

Talk to your doctor about the potential risks and benefits of Ozempic before starting treatment.

Does Ozempic need to be refrigerated?

Ozempic storage instructions

BEFORE FIRST USE: Ozempic should be stored in the refrigerator (between 36°F to 46°F or 2°C to 8°C) until you use it for the first time.

AFTER FIRST USE: After you have used the Ozempic pen for the first time, Ozempic can remain stored in the refrigerator or kept at room temperature (between 59°F to 86°F or 15°C to 30°C) for up to 56 days.

Keep in mind that Ozempic is sensitive to extreme temperatures. If the pen is exposed to temperatures higher than 86°F (30°C), it can go bad and will no longer be safe to use. If you live in places where it gets that hot, consider always storing Ozempic in the refrigerator and using a medical-grade container when you need to transport your medication.

Keep the pen cap on when not in use.

Make sure that the Ozempic in your pen is clear and colorless.

Can Ozempic stay out of the fridge?

After first use, Ozempic can be stored out of the fridge at room temperature (between 59°F to 86°F or 15°C to 30°C) for up to 56 days.

After you start using the Ozempic pen, it should be disposed of (thrown away) after 56 days, even if there is more Ozempic remaining in the pen. Write the date of disposal on your calendar so you do not forget.

Ozempic can be used until the expiration date if stored properly in the refrigerator at the correct temperature.

Do not store your Ozempic pens in the car. Always keep Ozempic away from the light and away from heat. Similar to other diabetes medications like Victoza, Trulicity, and many other injectable drugs, Ozempic is highly sensitive to low and high temperatures.

Can Ozempic be frozen?

Do not freeze Ozempic or store the pens directly next to the cooling element in your refrigerator. Do not take Ozempic if it was frozen.

Once frozen, the solution in Ozempic will break down and not regain its original efficacy. Ozempic is not safe for use after it has been frozen,  even if it has thawed, and you should throw it away and get a new pen.

What is the shelf life of Ozempic?

The shelf life of Ozempic is 24 months. After that, it must be disposed of according to local regulations. Talk to your pharmacist or healthcare provider about the best way to dispose of Ozempic.

The pen you are using should be thrown away after 56 days, whether it was kept in the refrigerator or at room temperature.

Unused Ozempic pens can be used until the expiration (EXP) date printed on the label if stored in the refrigerator.

How to dispose of the Ozempic pen and needle?

Put your Ozempic pen and needle in an FDA-cleared sharps disposal container right away after use. Your Ozempic pen and needle should not be thrown away in the household trash.

A household container can be used if you don’t have a specific FDA-cleared container for sharps disposal. If you are using your own container it should be one that is created from heavy-duty plastic and can be securely closed in a stable upright and leak-proof container. The lid should be tight and puncture-resistant whereby sharps are not able to come back out. It should be labeled properly to warn people of hazardous materials that are inside the container.

When your container for sharps disposal is nearly full, you should follow the disposal guidelines in your community. There are no special instructions for disposing of the Ozempic pen.

What are the side effects of Ozempic?

The most common side effects of Ozempic include:

Rare but serious side effects of Ozempic can include:

  • Low blood glucose (hypoglycemia)
  • Changes in vision
  • Inflammation of your pancreas (pancreatitis)
  • Kidney problems (kidney failure)
  • Serious allergic reactions
  • Gallbladder problems

You should talk to your doctor about the potential side effects of Ozempic before starting treatment.

When should you not use Ozempic?

Do not use Ozempic if you have an allergy to semaglutide or an allergy to any of the ingredients in Ozempic. Do not use Ozempic if you or anyone in your family has a history of medullary thyroid cancer (mtc) or Multiple Endocrine Neoplasia syndrome type 2.

Tell your physician about all of your medical conditions, including if you currently have or previously have had:

  • Kidney problems
  • Gallbladder problems
  • Pancreatitis
  • Liver problems
  • A history of alcoholism
  • Low blood sugar (hypoglycemia)
  • Any other medical conditions

You should not use Ozempic if you are currently pregnant or if you are planning to become pregnant. Ozempic can harm an unborn baby. If you become pregnant when you are using Ozempic, stop taking Ozempic and call your physician right away.

How does Ozempic work to control type 2 diabetes mellitus?

Ozempic is typically prescribed as a weekly injection administered subcutaneously into the thigh, upper arm or abdomen. Ozempic works by mimicking the effect of the hormone GLP-1. GLP-1 is a hormone that is released from the gut in response to food. It helps to regulate glucose metabolism by stimulating insulin release from the pancreas and by slowing gastric emptying. Ozempic increases insulin release when the blood sugar level is high, and it slows gastric emptying to help control blood sugar after meals. Ozempic is not meant to be used for individuals with type 1 diabetes.

Tell your doctor about all of the medications you take, including over-the-counter drugs, vitamins, and herbal supplements. Ozempic may affect how other medications work, and other medications may affect how Ozempic works.

You should not use Ozempic if you are pregnant or breastfeeding.

Ozempic is a safe and effective medication when used as directed. Talk to your doctor about the potential risks and benefits of Ozempic before starting treatment.

What doses of Ozempic are available?

Ozempic is available as a 0.5 mg or 1 mg dose injection. The recommended dose of Ozempic is 0.5 mg or 1 mg once weekly. Your dose may be increased to 2 mg once weekly if you do not achieve adequate glycemic control with the lower dose.

What do I do if I miss a dose?

If you have missed a dose of your Ozempic injection, inject the missed dose once you remember. If it is nearly time for your next dose, skip the dose that you had missed and inject the next dose at your regular time. Do not inject a dose that is double the amount of Ozempic to make up for a dose that was missed.

How do I use Ozempic pen?

  1. Remove the Ozempic pen from the refrigerator and allow it to reach room temperature for at least 30 minutes before use. Check the label to ensure that the new pen contains Ozempic.
  2. Wash your hands with soap and water.
  3. Remove the pen cap by twisting it counterclockwise and pulling it straight off. Do not throw away the pen cap.
  4. Inspect the Ozempic pen to make sure that the solution is clear and colorless. Do not use the Ozempic pen if the solution is cloudy or contains particles. Attach a new needle. Check the dose flow for each new pen.
  5. Select an injection site on your thigh, upper arm or abdomen. Pinch a fold of skin between your thumb and forefinger.
  6. Insert the needle into the fold of the skin at a 45-degree angle.
  7. Push the plunger down until it stops. Do not inject the Ozempic pen if you see a drop of blood in the needle or on the transparent window.
  8. Keep the needle in the skin for at least 6 seconds to ensure that all of the medication has been injected.
  9. Withdraw the needle from the skin and release the skin fold.
  10. Replace the pen cap by screwing it on clockwise until it is tight.
  11. Dispose of the Ozempic pen in a sharps container.

Rybelsus side effects and how to avoid them

Rybelsus is a brand-name medication that is manufactured by Novo Nordisk. It is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist and is used to help control blood sugar levels in adults with type 2 diabetes. While Rybelsus is generally well tolerated, there are some potential side effects that people should be aware of. The most common side effects of Rybelsus include nausea, headache, and upper respiratory tract infection. Less common, but more serious side effects, can include pancreatitis and low blood sugar levels.

Learn more about the side effects of Rybelsus and what you can do to avoid them.

What is Rybelsus (semaglutide)?

Rybelsus is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist and is used to help control high blood sugar levels in adults with type 2 diabetes. Type 2 diabetes may also cause other medical conditions that could result in tiredness, such as heart disease.

The active ingredient in Rybelsus is semaglutide. It is a glucagon-like peptide-1 receptor agonist (GLP-1) medication that works by mimicking the effects of the hormone glucagon, which helps to regulate blood sugar levels. Semaglutide is a man-made form of the hormone glucagon-like peptide-1 (GLP-1), which is found naturally in the body. Semaglutide is also the active ingredient in another brand-name medication called Ozempic which is also used to treat type 2 diabetes.

GLP-1 receptor agonists are a class of diabetes medications that work by mimicking the effects of the hormone glucagon, which helps to regulate blood sugar levels.

Rybelsus is available in tablet form and is taken by mouth once daily, with or without food. It should be taken at the same time each day to maintain an even level of the medication in your bloodstream.

Always check with your doctor or pharmacist before taking any medication, including Rybelsus, to make sure it is safe for you.

Rybelsus dosage

Rybelsus is available as a 7 mg, 14 mg, or 21 mg tablet. The starting dose of Rybelsus is typically 7 mg once daily. Your doctor may increase your dose gradually over time if needed.

You should take Rybelsus at the same time each day to maintain an even level of the medication in your bloodstream. You can take Rybelsus with or without food. Swallow the tablet whole.

If you miss a dose of Rybelsus, take it as soon as you remember. If it is almost time for you to take your next dose, skip the missed dose and continue on your regular dosing schedule. Do not take two doses of Rybelsus at the same time.

How effective is Rybelsus?

Rybelsus is FDA-approved to improve glycemic control in adults with type 2 diabetes mellitus. In clinical studies, Rybelsus was shown to lower fasting blood glucose levels, hemoglobin A1c levels (a measure of long-term blood sugar control), and post-meal blood sugar spikes.

In the event that Rybelsus, exercise, and diet are not enough to help you adequately lower your blood sugar, your healthcare provider may also prescribe other medications to use in combination with Rybelsus, such as metformin.

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Rybelsus side effects

It is possible to experience side effects while taking Rybelsus. For most people, the side effects usually go away within a few days or weeks.

The most common possible side effects of Rybelsus include:

Rybelsus can cause more serious side effects such as:

  • Low blood sugar levels (hypoglycemia)
  • inflammation of your pancreas (pancreatitis)
  • Serious allergic reactions
  • Vision changes / blurred vision
  • Kidney failure

If you experience any of these serious side effects, stop taking Rybelsus and seek medical attention immediately. Speak with your doctor right away about any side effect that bothers you or doesn’t go away.

You are encouraged to report any negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Rybelsus drug interactions

Rybelsus can interact with other medications including:

  • Insulin
  • Certain diabetes medications (sulfonylureas, thiazolidinediones)
  • Decongestants
  • Drugs to treat asthma
  • Blood pressure medications (ACE inhibitors, beta-blockers)
  • Some antidepressants (SSRIs, SNRIs)
  • Drugs used to treat an HIV infection
  • drugs to treat attention deficit-hyperactivity disorder
  • Drugs to suppress appetite/cause weight loss
  • Other oral medications

Before taking Rybelsus, be sure to tell your doctor about all of the medications you are taking to ensure they are safe to take at the same time.

Rybelsus warnings & precautions

Don’t take Rybelsus if:

  • You’re allergic to Rybelsus or any of its ingredients
  • You’re pregnant or breastfeeding
  • You have a history of pancreas problems
  • You have severe kidney problems or kidney disease
  • You have a history of low blood sugar levels (hypoglycemia)
  • You have a history of diabetic ketoacidosis
  • you or a member of your family has ever had medullary thyroid cancer (MTC)
  • you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2);

Talk to your doctor before taking Rybelsus if you:

  • Have or have had kidney problems
  • Have or have had pancreas problems
  • Have or have had low blood sugar levels (hypoglycemia)
  • Are pregnant or breastfeeding
  • Have digestive problems
  • Have type 1 diabetes
  • Have diabetic retinopathy
  • Or a member of your family has or has had Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or medullary thyroid carcinoma (MTC) or other thyroid tumors
  • Have a high heart rate

You should always check with your doctor or pharmacist before taking any medication, including Rybelsus, to make sure it is safe for you.

Other warnings you should know about

  • Children and adolescents: Rybelsus is not for use in children or adolescents under 18 years old.
  • Elderly: The safety and efficacy of Rybelsus have not been studied in elderly patients.
  • Pregnant women: There are no data on the use of Rybelsus in pregnant women. Animal studies have shown reproductive toxicity
  • Driving: Rybelsus may cause dizziness or lightheadedness. If you experience these symptoms, do not drive or operate heavy machinery.
  • Alcohol: Avoid alcohol while taking Rybelsus as it can increase your risk of low blood sugar levels (hypoglycemia).

How to avoid Rybelsus side effects

The best way to avoid side effects is to take Rybelsus as directed by your doctor. Follow your doctor’s instructions carefully and do not take more or less than prescribed.

If you are experiencing nausea as a side effect, you can try to:

  • Eat bland, low-fat foods, like rice, toast or crackers
  • Eat foods that contain water such as gelatin and soups
  • Avoid fried, sweet or greasy foods
  • Avoid lying down after eating
  • Go outdoors for some fresh air
  • Eat your food more slowly
  • Drink clear or ice-cold drinks

If you experience any side effects, talk to your doctor or pharmacist. They may be able to recommend ways to help reduce or prevent some of the side effects.

1. Stick to the recommended dosage

Take your prescribed dose of Rybelsus that has been recommended by your healthcare professional. Do not take more or less than prescribed.

2. Monitor your blood sugar levels

If you have diabetes, it is important to monitor your blood sugar levels closely while taking Rybelsus. Check your blood sugar levels as directed by your doctor and report any changes to your doctor immediately.

3. Drink plenty of fluids

Drink eight to 10 glasses of water or fluids every day to help prevent dehydration, which can make side effects worse.

4. Avoid alcohol

Avoid drinking alcohol while taking Rybelsus as it can increase your risk of low blood sugar levels (hypoglycemia).

5. Don’t skip meals

Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia).

6. Check your feet

If you have diabetes, check your feet for any cuts, sores, or redness regularly. Tell your doctor if you experience any problems with your feet while taking Rybelsus.

7. Know the signs and symptoms of low blood sugar levels

Signs and symptoms of low blood sugar levels (hypoglycemia) include feeling shaky, sweating, fast heartbeat, dizziness or lightheadedness, hunger, confusion, and headache. If you experience any of these symptoms, eat or drink something that will raise your blood sugar level right away.

8. Monitor your weight

Rybelsus may cause weight loss. If you experience unexplained weight loss while taking Rybelsus, get medical advice from your doctor.

9. Tell your doctor about all medications you’re taking

Be sure to tell your doctor about all other medications you’re taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with Rybelsus.

10. Get regular medical checkups

If you have diabetes, it is important to get regular medical checkups and monitor your medical conditions. Your doctor will monitor your blood sugar levels and may adjust your dose of Rybelsus as needed.

Does Jardiance cause weight loss?

Jardiance may help individuals with type 2 diabetes lose weight while taking this medication. It is not FDA-approved for people without type 2 diabetes.

What is Jardiance (empagliflozin)?

Jardiance is a brand-name medication used to treat type 2 diabetes mellitus. It is an oral tablet taken once per day and is used in addition to exercise and diet.

The active ingredient in Jardiance is empagliflozin. It is in a drug class called sodium-glucose cotransporter 2 or SGLT2 inhibitors. Jardiance works by helping the kidneys get rid of glucose from your body. In people with type 2 diabetes, the body does not use insulin properly. This causes the body to make more glucose, which can lead to high blood sugar levels. Jardiance helps to lower blood sugar levels by helping the kidneys get rid of glucose from the body.

Jardiance is used to treat symptoms of type 2 diabetes such as high blood glucose levels. It is not used to treat type 1 diabetes.

It is manufactured by Boehringer Ingelheim Pharmaceuticals and Eli Lilly.

Does Jardiance cause weight loss?

Jardiance is not FDA-approved for the treatment of weight loss. There is some evidence that people who take Jardiance have experienced weight loss. One clinical study found that people who took Jardiance lost an average of 2-3% of their body weight. However, it’s unclear if this weight loss is due to the medication or other factors such as changes in diet or exercise.

In clinical trials, Jardiance was linked to statistically significant reductions in hemoglobin A1C (a diagnostic tool used during type 2 diabetes treatment) and fasting plasma glucose, as well as measures of blood sugar control, when compared to other people who were taking an inactive placebo. Jardiance is classified as an SGLT-2 inhibitor and carries a low risk of low blood sugar (hypoglycemia).

In addition to controlling blood sugar levels, Jardiance has been found to successfully reduce both weight and the distribution of body fat including abdominal fat (visceral adiposity tissue or VAT). Abdominal body fat increases the risk of stroke, heart attack, and other cardiovascular events. Reducing belly fat helps with reducing the risk of death from heart disease or other cardiovascular health conditions.

If you’re considering taking Jardiance for weight loss, seek medical advice from your doctor or healthcare provider about the potential risks and benefits. They can help you decide if this medication is right for you.

Can I lose weight by taking Jardiance with metformin?

It is possible to lose weight while taking metformin with Jardiance. In a 24-week clinical trial study with over 600 participants, Jardiance was given as an add-on therapy to metformin and was proven to significantly improve weight loss in the trial.

The clinical trial also found that weight loss was also statistically significant when Jardiance was taken with metformin and a sulfonylurea in a clinical trial study that was conducted over a 24-week period.

Jardiance side effects

Most prescription drugs including Jardiance may have possible side effects.

Common side effects of Jardiance include:

  • Low blood sugar levels (hypoglycemia),
  • Dehydration
  • Urinary tract infections
  • Genital yeast infections

Serious side effects are rare but can include:

  • Diabetic ketoacidosis (a build-up of ketones in the blood or urine)
  • Kidney disease or kidney problems
  • Serious bacterial infection (ie Necrotizing fasciitis)
  • Serious allergic reactions.
  • Increased cholesterol levels

Jardiance is not right for everyone. Be sure to tell your doctor about all of your medical conditions and allergies before taking this diabetes drug. Discuss with your doctor if you are on any other medications, including diuretics, medications for heart disease, supplements or vitamins. Tell your doctor if you are pregnant or breastfeeding. This medication may be harmful to an unborn baby.

Jardiance drug interactions

Jardiance can interact with vitamins, drugs or herbs that you are taking which can change the way a drug is meant to work or cause harm.

Jardiance can be added to other diabetes medications (ie metformin, insulin sulfonylurea) but the dosage may need to be lowered since Jardiance works to lower your blood sugar levels.

Your physician should review and manage all of your medications carefully to avoid any issues. Always discuss with your doctor about all supplements, herbs, vitamins or medications that you take and discuss if there is a possibility of any drug interactions.

Is Jardiance used for cardiovascular disease?

Cardiovascular disease includes conditions that affect the heart and blood vessels.

There is some evidence that Jardiance may help to lower the risk of cardiovascular events such as heart attacks and strokes in people with type 2 diabetes. Blood pressure and heart rate were found to be lower in people taking Jardiance compared to those not taking the medication. However, more research is needed to confirm these findings.

Jardiance has been shown to reduce the risk of cardiovascular death in people with type 2 diabetes and cardiovascular disease. In a clinical trial, Jardiance was shown to reduce the risk of cardiovascular death by 38%.

If you have type 2 diabetes and are at risk for cardiovascular disease, your doctor may prescribe Jardiance to help reduce your risk of cardiovascular death.

Does Jardiance reduce blood pressure?

Jardiance is not FDA-approved to treat high blood pressure. However, positive effects on blood pressure were discovered during clinical trials. Blood pressure levels were found to be reduced when using Jardiance alone and also with metformin.

When should I take Jardiance?

Jardiance is usually taken once daily with or without food. You should take Jardiance at the same time each day to maintain an even level of the medication in your blood.

Your doctor will determine the best dose for you based on your medical conditions and response to treatment.

Bottom line

  • Jardiance may result in moderate weight loss for people who take this medication alone or in combination with other medications such as metformin or a sulfonylurea.
  • Overall, people who take Jardiance may lose anywhere 2% to 3% of their weight. However, the weight loss percentage is variable and may be influenced by many factors including exercise and diet.
  • In addition to possible weight loss, Jardiance can also have a positive effect on your cardiovascular (heart) health and reduce the risk of death from heart-related conditions.
  • Taking this medication may also have positive effects on kidney health, blood pressure, and possible risks of hypoglycemia (low blood sugar).

Switching from Vyvanse to Mydayis

Vyvanse and Mydayis are both drugs for the treatment of attention deficit hyperactivity disorder (ADHD). They are both amphetamine products available as extended-release formulations making them long-acting drugs. Switching medication is often recommended by healthcare professionals when ADHD symptoms are not controlled or when there are unacceptable adverse effects. There are many ADHD medication treatment options to consider. How and when to switch medications should be done under your doctor’s medical advice and guidance. Learn more about what to expect when switching from Vyvanse to Mydayis.

What is ADHD?

ADHD is the abbreviation of Attention Deficit Hyperactivity Disorder characterized by inattention, hyperactivity, and impulsivity. It is a neurodevelopmental disorder that is typically diagnosed in childhood, commonly in males but underdiagnosed in females. According to the Centers for Disease Control and Prevention, there are an estimated 6.4 million children and adolescents diagnosed with ADHD in the United States.

Mental health professionals have identified three types of ADHD, based on the main symptoms involved:

  • Inattentive type ADHD
  • Hyperactive-impulsive ADHD
  • Combination of inattentive and hyperactive-impulsive type ADHD

ADHD symptoms can vary from person to person, depending on the subtype of ADHD.

What is Vyvanse?

Vyvanse is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire PLC. Vyvanse is the brand name of lisdexamfetamine dimesylate, a derivative of amphetamine. Vyvanse contains the prodrug lisdexamfetamine, which is metabolized into L- lysine, and dextroamphetamine once it is in the body.

Vyvanse is a prescription drug belonging to a class of drugs known as Central Nervous System stimulants. It is used to treat:

  • ADHD in adults, adolescents, and children over the age of 6 years
  • Moderate to severe binge eating disorder

Vyvanse is not recommended for weight loss and obesity. Vyvanse is a prescription stimulant medication but is also classed as a Schedule II controlled substance. As a controlled substance, doctors usually prescribe small doses.

Other drugs included in the class of central nervous system stimulants include Concerta (methylphenidate), Ritalin, and Focalin (dexmethylphenidate). Non-stimulant ADHD treatments such as Strattera are also available.

What is Mydayis?

Mydayis is a prescription medication given to adults and children aged 13 and over to treat attention deficit hyperactivity disorder (ADHD). It is the same drug as Adderall XR but with a slightly longer duration time.

Mydayis contains four active ingredients; dextroamphetamine sulfate, amphetamine sulfate, dextroamphetamine saccharate, and amphetamine aspartate monohydrate. These are mixed amphetamine salts that stimulate activity in your brain.

How do Vyvanse and Mydayis work in the body?

Vyvanse and Mydayis belong to a class of drugs known as amphetamines. By working on the central nervous system Vyvanse and Mydayis increase activity in areas of the brain that help you with your concentration and behavior. They work specifically on the chemicals dopamine and norepinephrine in the brain. These neurotransmitters, dopamine, in particular, are involved in feelings of pleasure, focus, and finding things interesting. Stimulant medications reduce the symptoms of ADHD making conditions such as inattention, poor decision making, and poor impulse control much less of a daily problem.

How long does it take for Vyvanse to work?

It will take about 1 to 3 hours for Vyvanse to work when taken on an empty stomach to reach its maximum level in your blood. If a Vyvanse chewable tablet is taken on an empty stomach it will take slightly longer to kick in. Vyvanse can provide a steady experience due to slower absorption with your dose lasting up to 14 hours.

It is important to remember these timings are rough estimates because several factors need to be taken into consideration such as drug tolerance, weight, height, and sleep patterns to name a few.

For Vyvanse to start working in your body, lisdexamfetamine must react with your blood and be converted into the active drug dextroamphetamine. Vyvanse is a prodrug, meaning it is converted from an inactive form into an active form in your body by chemicals or enzymes.

Forms and dosages of Vyvanse

The recommended starting dose of Vyvanse is 30 mg. Your doctor may periodically increase or decrease your dosage to help control ADHD symptoms and manage any side effects. You’ll work with your doctor to find an ADHD dose that’s best for you.

Vyvanse is available in chewable tablet form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg & 60 mg.

Vyvanse is also available in capsule form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg & 70 mg.

How long does it take for Mydayis to work?

It will take Mydayis around 2 hours to start working in your body and its effects can last up to 16 hours. You can experience increased energy and focus quicker, which may be useful if you need immediate relief from ADHD symptoms. Just like Vyvanse, these duration times are just approximate.

Forms and dosages of Mydayis

Mydayis is available in four extended-release capsule strengths: 12.5 mg, 25 mg, 37.5 mg, and 50 mg.

Mydayis is taken as a daily dose orally, with or without food.

Doctors will usually prescribe a lower dose when you first start taking a medication and gradually titrate it until they find the right therapeutic dose for you and your symptoms.

Vyvanse vs Mydayis

Vyvanse is a similar medication to Mydayis. Both are central nervous system stimulants derived from amphetamines, and both are used for the treatment of ADHD. Vyvanse is also used for the treatment of binge eating disorders (BED), but Mydayis isn’t.

Although the two medications are similar and work in a similar way, they contain different active ingredients. Mydayis contains four different kinds of amphetamine salts, whereas Vyvanse only contains lisdexamfetamine, which is converted to dextroamphetamine inside your body.

Both Vyvanse and Mydayis are effective treatments for ADHD, and they both cause similar side effects. Vyvanse only has an effect once it’s been converted into your body. It’s thought to have a lower risk of substance abuse than Mydayis because of its mode of action that requires enzymes in your body to convert it into its active form.

One important difference is that Vyvanse is a prodrug, meaning lisdexamfetamine is converted into dextroamphetamine once it is in the body. Vyvanse remains inactive until the body breaks it down in the bloodstream. This is not the case with Mydayis. Mydayis capsules have a triple-bead release action and contain three types of beads per capsule: 33% of the beads are immediate-release, 33% of the beads are delayed-release working at pH 5.5 and 33% of the beads are delayed-release working at pH 7.0. Mydayis releases its medication in three phases whereas Vyvanse releases its active ingredient steadily over the course of the day.

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When is it recommended to switch from Vyvanse to Mydayis?

  • When Vyvanse is not providing symptom control over the course of the day. Mydayis has a slightly longer duration of action and your doctor may want to switch you over
  • When Vyvanse is causing undesirable adverse effects a switch to a different amphetamine may be recommended by your doctor

Stimulants are powerful medications that wear off rapidly. They’re also completely eliminated from your body by the end of their specified duration, so it’s possible to stop taking them one day and start another stimulant on another occasion. Your doctor will tell you how this transition should be made when changing from Vyvanse to Mydayis.

Are Mydayis and Vyvanse safe to use?

Mydayis and Vyvanse are both controlled substances that can be abused and become habit-forming. Both have the potential to be addictive. However, when used as prescribed to treat a medical condition, Vyvanse and Mydayis shouldn’t become habit-forming.

Amphetamines can be used as recreational drugs. This is where they aren’t used as prescribed or to treat an indicated medical condition. Recreational use, particularly heavy use of amphetamines, can lead to physical dependence (addiction). It can alter the way your body works. You can also become more tolerant of the drug, requiring higher doses to get the same desired effect.

Vyvanse has less potential to be used recreationally than other amphetamines, as it’s slower acting, and won’t be absorbed quicker if it’s crushed or ground up. If used as directed by a doctor to treat ADHD or BED, it shouldn’t become addictive. Research has also shown that long-term use of stimulants from childhood to treat conditions like ADHD reduces the chances of addiction. Your healthcare provider should assess your risk of Vyvanse or Mydayis addiction before prescribing and should monitor you while you take it.

Vyvanse and Mydayis are Schedule II drugs, which means there is a potential for abuse and dependency. Since Vyvanse needs to be converted in the body, it can’t be inhaled or injected as a way to become high, so it is less likely to be misused than Mydayis and other stimulant medications. Always store your medications safely and away from other people.

Adderall and Vyvanse side effects

The most common side effects of Mydayis and Vyvanse in children, adolescents, and/or adults with ADHD are:

  • Anorexia
  • Anxiety
  • Dizziness, nausea
  • Blurred vision
  • Dry mouth
  • Irritability
  • Insomnia
  • Upper abdominal pain, stomach pain, vomiting, loss of appetite, decreased weight, diarrhea, constipation
  • Motor tics (repeated muscle movements)
  • Increased heart rate

In rare instances, Mydayis and Vyvanse can cause more serious side effects. These can include:

  • Serious cardiovascular reactions e.g. chest pain
  • Sudden death has been reported with CNS stimulant treatment at recommended doses in pediatric patients with structural heart defects or other serious heart problems
  • Sudden death, stroke, and heart attacks in adults
  • High blood pressure and increase in heart rate
  • Suppression of growth – monitor height and weight in pediatric patients
  • Circulation problems, such as skin color changes, a cold feeling including Raynaud’s phenomenon
  • Serotonin syndrome – an increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations
  • New or worsening psychosis, bipolar disorder, or mental health issues
  • Withdrawal symptoms if you suddenly stop using this medication – severe tiredness, sleep problems, mental/mood changes such as depression
  • Severe allergic reactions e.g. hives, shortness of breath

Your doctor will assess the benefits of using Mydayis and Vyvanse against your risk of side effects. You are encouraged to report negative side effects or adverse reactions of Vyvanse and Mydayis to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Mydayis and Vyvanse drug interactions

Mydayis and Vyvanse can interact with other medications, including prescription drugs. In some instances, this can change how it and other medications work. It can even increase the likelihood and severity of some side effects. Medications that are known or thought to interact with Mydayis and Vyvanse include:

  • Monoamine oxidase inhibitors, MAOIs, (methylene blue, phenelzine, or selegiline)
  • Tricyclic antidepressants (desipramine or protriptyline)
  • Medications that affect your serotonin system (SSRIs or SNRI antidepressants, triptans, fentanyl, or St. John’s Wort)

Read the full prescribing information for Mydayis and Vyvanse and always speak with your healthcare provider for medical advice about your medicine so they can monitor and evaluate your condition. Always inform your healthcare provider of all your medical conditions, and any medications you are taking, including over-the-counter meds and supplements.

Vyvanse and Mydayis are two commonly prescribed ADHD meds. While both mediations work to relieve symptoms, it may take trial and error to determine which medication will work best for you.

Why is Eliquis so expensive?

Eliquis (apixaban) is a prescription medication that works by blocking certain clotting proteins in the blood, which prevents clots from forming. It is an expensive drug with a list price of $529 for a 30-day supply. Learn more about why Eliquis is so expensive and what options are available to help you save money.

What is Eliquis (apixaban)?

Eliquis is an FDA-approved brand-name medication with the active ingredient apixaban, and is part of a class of drugs called anticoagulants (Xa inhibitors) that are also known as blood thinners. It is used for:

  • reducing the risk of stroke and blood clots in people who have atrial fibrillation (AFib), a type of irregular heartbeat
  • treating blood clots in the veins of the legs (deep vein thrombosis – DVT) or lungs (pulmonary embolism – PE), and reducing the risk of them occurring again
  • reducing the risk of forming a blood clot in the legs (DVT) and lungs (PE) of people who have recently had hip or knee replacement surgery

The FDA approved Eliquis from manufacturers Bristol Myers Squibb and Pfizer in December 2012.

Other popular anticoagulants include Xarelto (rivaroxaban), Pradaxa (dabigatran) and Savaysa (edoxaban).

Eliquis side effects

Like most medications, Eliquis may cause side effects. The most common side effects of Eliquis include bleeding, spinal or epidural blood clots (hematoma), and a possible reaction to Eliquis itself.

You may have a higher risk of bleeding if you take this medication with other medicines that increase your risk of bleeding, such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, heparin, selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) and other medicines that are used to help treat or prevent blood clots.

To avoid drug interactions with Eliquis, talk to your doctor or pharmacist about all of your medical conditions and any other prescription medications, over-the-counter products, vitamins or supplements you are taking. If you experience any side effects or possible signs of an allergic reaction, speak with your healthcare provider right away.

RELATED: Eliquis side effects and how to avoid them

How much does Eliquis cost?

The cost of Eliquis will depend on your health insurance company’s plan and the coverage for this drug including the copay and deductible. Medicare usually covers Eliquis through Medicare Advantage Part C or Medicare Part D prescription drug coverage plans.

According to the manufacturer’s website, individuals with commercial insurance pay $45 per month for Eliquis, and 5 out of 10 people pay $15 per month or less.

People who have a health insurance plan that includes coverage through Medicare are paying $46 per month on average, and 5 out of 10 people pay $30 or less.

Low-Income Subsidy patients may pay $0 to $9.85 per month when using the Social Security Administration’s Extra Help program.

Those who are covered under Medicaid pay $4 per month on average, and 5 out of 10 people pay $0.

For patients without prescription drug insurance who need to pay the list retail price, the estimated out-of-pocket cost for a 30-day supply of this medication is $529, according to the manufacturer’s website.

Generic Eliquis is not yet available

Eliquis is a brand-name medication and there are currently no generic Eliquis alternatives available. Generic medications are chemically equivalent to their brand-name counterparts and are sold at a lower cost. Once the generic of Eliquis is available for sale, the generic drug cost for apixaban will be much more affordable than the brand name Eliquis.

The patents for Eliquis expire on April 2028, which is the earliest date when a generic alternative will become available.

The FDA (U.S. Food and Drug Administration) requires generic drugs to be as safe and effective as their brand-name drug counterparts. Generic drugs are also subject to the same manufacturing quality standards as brand-name drugs. They must have the exact same active ingredient, strength, dosage form, route of administration, and indications for use.

As multiple generic drug companies will likely sell the generic version of the drug after the patent expires, the increase in competition will likely lower the cost of the medication so it will become more affordable for patients.

RELATED: Brand vs generic drugs, FDA approves first generic Eliquis, apixaban

Patent laws

Once a new drug is approved, the pharmaceutical company is granted a 20-year patent to sell the drug exclusively. For medications that are used to treat rare diseases which affect 200,000 or fewer people in the United States, the Orphan Drug Act extends the patent protection by an additional seven years.

During this patent protection period, the pharmaceutical company has exclusivity for the sale of the drug which is intended to allow the company to recoup the research and development investment that was required to discover the drug. After the patent for the drug expires, other pharmaceutical companies can request authorization from the FDA to start selling generic versions of the drug.

The patents for Eliquis will expire on April 2028, which is the earliest date a generic pharmaceutical company will be able to apply for FDA authorization to sell a generic version of Eliquis.

Unregulated pricing for pharmaceuticals

Americans pay the highest prescription drug prices in the world. In contrast with other developed countries like Canada, pharmaceutical pricing isn’t regulated in the United States, which means that drug companies can charge whatever they want for their medications in an attempt to incentivize drug companies to invest in developing new drugs.

A study by RAND analyzed prescription drug prices in the United States and concluded that prescription drug prices are on average 2.56 times higher in the US than in other OECD countries. Another study by AARP concluded that the annual increases in pharmaceuticals in the United States have continuously outpaced the rate of inflation.

How do I save on Eliquis (apixaban)?

The expensive price of Eliquis can make this medication unaffordable for many people, especially those without prescription drug insurance. Fortunately, there are several options to help you save money:

  1. Eliquis Copay card and free-trial offer – the manufacturer provides a savings card to people who meet the eligibility requirements. You can pay as little as $10 for a 30-day or 90-day supply of Trintellix. The maximum savings are $100 for a 30-day supply or $300 for a 90-day supply. Make sure to check the terms and conditions on the manufacturer’s website to determine if you are eligible as this offer may change.
  2. Patient assistance programs – you may be eligible for enrollment into a patient assistance program for Eliquis.
  3. Ask your healthcare professional if they can provide free Eliquis samples – the manufacturer may also provide your healthcare provider with free Eliquis samples.
  4. Get medical advice from your healthcare provider and find out if there are any alternative medications that can help you save money – find out from your prescribing doctor if there are any Eliquis alternatives that can work for you.
  5. Shop around at mail-order pharmacies – medication prices vary by pharmacy so it’s always a good idea to check prices at multiple pharmacies when purchasing your medication.
  6. Eliquis coupons – you may be able to find an Eliquis manufacturer coupon that can help you save more money.
  7. Help from Medicaid – find out if there is a state Medicaid plan available that may help cover the cost of your Eliquis prescription.

Why is Trintellix so expensive?

Trintellix is a brand-name prescription medication used to treat major depressive disorder (MDD). The drug is classified as a serotonin reuptake inhibitor (SSRI), which works by increasing levels of serotonin in the brain.

Trintellix is one of the most expensive antidepressant medications on the market, with a retail price of around $444 for a 30-day supply, according to the manufacturer. The high cost is likely due to a lack of generic alternatives for this medication.

Learn more about why Trintellix is so expensive and what you can do to save money on this medication.

What is Trintellix (vortioxetine)?

Trintellix is an FDA (U.S. Food and Drug Administration) approved brand-name medication used to treat major depressive disorder (MDD), which is also known as clinical depression. Depression is a serious mental health condition. Trintellix was formally known as  Brintellix, which was discontinued by the manufacturer.

Trintellix contains the active ingredient vortioxetine and belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). These drugs work by increasing levels of the neurotransmitter serotonin in the brain, which can help improve mood and relieve symptoms of depression.

Trintellix was approved by the FDA in 2013 and is manufactured by Takeda Pharmaceuticals and Lundbeck. It is available in tablet form and is taken orally once daily, with or without food.

Trintellix and other antidepressants may increase suicidal thoughts and actions in young adults 24 years of age and younger, especially within the first few months of treatment or when the dose of the medication is changed. Depression and other mental illnesses are generally the most important causes of suicidal thoughts or actions. This medication is not for use in children under 18.

Trintellix is not known to cause any changes in weight such as weight loss or weight gain.

Trintellix side effects

Like most medications, Trintellix can cause side effects. The most common side effects of Trintellix include nausea, constipation, and vomiting.

While most people tolerate Trintellix well, it can cause serious side effects in some people including serotonin syndrome, increased risk of bleeding, trouble sleeping, manic episodes in people with bipolar disorder, discontinuation syndrome, eye problems, low levels of salt (low sodium levels) in your blood, and sexual side effects such as decreased libido or erectile dysfunction.

MAOI (monoamine oxidase inhibitors) interact with Trintellix and cannot be taken with this medication. Do not start using Trintellix if you have stopped taking an MAOI in the last 14 days. Taking Trintellix with MAOIs can lead to dangerous side effects, including very high blood pressure, severe headache, chest pain, and increased body temperature.

Trintellix and Prozac (fluoxetine) are similar medications and belong to the same class of drugs (SSRIs). These medications can also increase the risk of glaucoma, or abnormally low blood pressure in the eye. Glaucoma can lead to optic nerve damage and blindness if not promptly treated.

Talk to your doctor about whether you should take Trintellix if you are breastfeeding. Trintellix can pass into your breast milk and may harm your baby.

Trintellix should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Trintellix, tell your doctor immediately.

To avoid drug interactions with Trintellix, talk to your healthcare professional about all of your medical conditions and any other prescription medications (including migraine medicines called triptans, tricyclic antidepressants, and opioids such as fentanyl and tramadol), over-the-counter, or supplements you are taking. If you experience any side effects or possible signs of an allergic reaction, speak with your healthcare provider right away.

RELATED: Trintellix side effects and how to avoid them

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How much does Trintellix cost?

The cost of Trintellix will depend on your health insurance plan and the coverage for this drug including the copay and deductible.

According to the manufacturer’s website, commercially insured patients may pay as little as $10 for a 30-day or 90-day supply of their Trintellix prescriptions. Average monthly out-of-pocket costs for Medicare patients are estimated at $40.19 and the average monthly out-of-pocket costs for Medicaid patients are $1.05.

For people without prescription drug insurance who need to pay the list price out-of-pocket, the estimated price for a 30-day supply of Trintellix is $444.14, according to the manufacturer.

Generic Trintellix is not yet available

Trintellix is a brand-name medication and there are currently no generic Trintellix alternatives available. Generic medications are generally a lot cheaper than their brand-name counterpart drugs.

The patents for Trintellix expire on June 2027 which is the earliest date when a generic alternative will become available.

The FDA requires generic drugs to be as safe and effective as their brand-name counterparts. Generics must also meet other FDA requirements including being manufactured under strict quality control standards and being bioequivalent to the brand-name drug which means they have the same active ingredient, strength, dosage form, route of administration, and indications for use.

As multiple generic pharmaceutical companies will likely sell the generic version of the drug after the patent expires, the increased competition will likely result in a significant reduction in the price, providing for more affordable access to the medication.

RELATED: Brand vs generic drugs

Patent laws

When a pharmaceutical company receives the first FDA approval for a drug, it is given a 20-year patent. During this time, the pharmaceutical company has the exclusive right to sell the drug that allows them time to recoup their research & development investment that was required to discover the drug and bring it to market. After the patent expires, other companies are allowed to sell generic versions of the drug. Generic drugs must be approved by the FDA and are usually much cheaper than their brand-name counterparts.

For drugs that are used to treat rare diseases that affect 200,000 or fewer people in the United States, the Orphan Drug Act extends the patent protection for pharmaceutical companies by an additional seven years.

The patents for Trintellix will expire on June 2027, which is the earliest date a generic pharmaceutical company will be able to apply for FDA authorization to sell a generic version of Trintellix.

Unregulated pricing for pharmaceuticals

Pharmaceutical pricing isn’t regulated in the United States which means that pharmaceutical companies are able to set pricing at their discretion without any regulation. In many cases, the same medication will sell for a significantly lower price in other developed countries that regulate drug prices.

A report by RAND reports that prescription drug prices in the United States are on average 2.56 times higher than in other OECD countries. Another report by AARP found that the annual increases in the price of prescription drugs in the United States are outpacing the rate of inflation.

With an estimated price of $444.14 for a 30-day supply of Trintellix, uninsured individuals who suffer from major depressive disorder will be paying a high price for this prescription drug until the generic version is approved.

How do I save on Trintellix?

The expensive price of Trintellix can make treatment unaffordable for many people who suffer from major depressive disorder. Fortunately, there are several options to help you save money:

  1. Trintellix Savings Card – Takeda provides a savings card to people who meet the eligibility requirements. You can pay as little as $10 for a 30-day or 90-day supply of Trintellix. The maximum savings are $100 for a 30-day supply or $300 for a 90-day supply. Make sure to check the terms and conditions on the Takeda website to determine if you are eligible as this offer may change.
  2. Patient assistance program – you might be eligible for enrollment into a patient assistance program for Trintellix.
  3. Ask your healthcare provider if they can provide free Trintellix samples – The manufacturer may also provide your healthcare provider with free Trintellix samples that are intended for people that need help getting started on the medication.
  4. Get medical advice from your healthcare provider and find out if there are any alternative medications that are right for you – find out from your prescribing doctor if there is a Trintellix alternative that may work for you, such as Prozac (fluoxetine), Wellbutrin SR (bupropion), Wellbutrin XL (bupropion), Lexapro (escitalopram), Viibryd (vilazodone), or Cymbalta (duloxetine).
  5. Shop around at mail-order pharmacies – prescription drug prices vary by pharmacy so it’s recommended to shop around for the best possible price when purchasing this medication.
  6. Trintellix coupons – you may be able to find a Trintellix manufacturer coupon that can help you save more money.
  7. Help from Medicaid – find out if there is a state Medicaid plan available that may help cover the cost of your Trintellix prescription.

Why is Xiidra so expensive?

Xiidra is a brand-name prescription eye drop used to treat the symptoms and signs of dry eye disease.

It is expensive because it’s a brand-name drug with no generic alternative versions available yet. Learn more about why Xiidra is so expensive and what you can do to save money on this medication.

What is Xiidra (lifitegrast)?

Xiidra is an FDA-approved brand-name ophthalmic solution used to treat the symptoms and signs of dry eye disease. It is designed to target a source of inflammation that may cause dry eye syndrome.

In clinical studies, Xiidra was shown to, on average, reduce eye symptoms at 12 and 6 weeks, and provide relief for some patients in as little as 2 weeks. It was also found to reduce the signs of dry eye by week 12 in some patients.  This medication may provide lasting relief of symptoms in as little as 2 weeks for some people with continued twice-daily use.

Dry eye disease is a condition that occurs when your body doesn’t produce enough tears, and the tears aren’t able to provide adequate lubrication for your eyes. This can happen if your tear production is decreased or if your tears are too watery and evaporate too quickly. It can also cause symptoms like burning, stinging, itching, and redness.

Xiidra contains the active ingredient lifitegrast and is packaged in single-dose vials that hold 0.2mL of solution. It comes as a preservative-free liquid solution that’s used as eye drops. It’s available in the dosage strength 5% solution. Xiidra is approved for use in people ages 17 years and older.

Side effects of Xiidra

The most common side effects of Xiidra include eye irritation, blurred vision or discomfort vision when Xiidra eye drops are applied to the eyes including a burning sensation during application, and an unusual taste sensation.

If you wear contact lenses, make sure to remove them prior to using Xiidra. You can reinsert the contact lenses at least 15 minutes after your dose.

Talk to your healthcare professional about all of your medical conditions and any other prescription medications, over-the-counter, or supplements you are taking. If you experience any side effects or possible signs of an allergic reaction, speak with your eye specialist (ophthalmologist) or healthcare provider right away.

Xiidra vs. Restasis

Xiidra (lifitegrast) and Restasis (cyclosporine) are both brand-name prescription eye drops used to treat chronic dry eye. Xiidra is manufactured by Novartis (previously Shire) and Restasis is manufactured by Allergan. Restasis is a 0.05% eye emulsion that is instilled in both eyes every 12 hours or twice per day.

In addition to dryness, Xiidra and Restasis can also treat other symptoms of dry eye disease, including eye fatigue, redness in the eyes, blurry vision, and itchiness in the eyes.

Both drugs have anti-inflammatory properties but are not the same. They are used as eyedrops and are typically instilled into the affected eyes twice daily.

Xiidra and Restasis can be used together, or in combination with other medications to treat dry eye syndrome. Speak with your healthcare provider to find out which medications will work best for treating your condition. You may be referred to an eye care specialist or doctor who specializes in ophthalmology. Your healthcare provider may also recommend an over-the-counter product like artificial tears which is used for the treatment of occasional dryness or irritation in the eyes.

How much does Xiidra cost?

Xiidra costs will vary depending on your health insurance plan and the coverage for this medication.

According to the manufacturer’s website, approximately 1,500,000 people have been prescribed Xiidra and patients with commercial insurance may pay as little as $0 for their Xiidra prescriptions.

For people without prescription drug insurance who need to pay the cash price out of pocket, the list price for a 30-day supply of Xiidra is $553.54, according to the manufacturer.

Generic Xiidra is not yet available

Xiidra is a brand-name prescription eye drop and there are currently no generic alternatives for Xiidra available. Generic drugs are much cheaper than brand-name drugs.

The earliest date that a generic for Xiidra will become available is April 15, 2029, when patents for Xiidra expire. Until the generic drug is approved by the FDA, individuals who suffer from chronic eye disease will need to purchase the brand-name drug, Xiidra.

RELATED: Brand vs generic drugs

Patent laws

Pharmaceutical patent laws prevent other companies from selling a generic version of the brand-name drug for a certain number of years. In most cases, the patent will expire in 20 years. This exclusivity period provides the proprietor of the drug to recoup their research and development (R&D) costs before other generic drug manufacturers can produce generic versions of the medication. After the patents expire, other companies are then allowed to sell generic versions of the medication.

The FDA must also approve all generic drugs before they can be sold in the United States. Generics must contain the same active ingredients as the brand-name drug and work in the same way. They also must meet the same quality standards as their brand-name counterparts. As multiple generic pharmaceutical companies will likely sell the generic version of the drug, the increased competition will likely result in a significant reduction in the price, providing for more affordable access to the medication.

For medications that are used in the treatment of rare diseases that affect 200,000 or fewer people in the United States, the Orphan Drug Act provides pharmaceutical companies an additional seven years of patent protection.

The patents for Xiidra are expected to expire on April 15, 2029, which is the earliest date a generic pharmaceutical company can apply for FDA approval to market its generic version of the drug.

Unregulated pricing for pharmaceuticals

Pharmaceutical pricing isn’t regulated in the United States which means that pharmaceutical companies are able to set pricing at their discretion without any regulation. In many cases, the same medication will sell for a significantly lower price in other developed countries that regulate drug prices.

A report by RAND found that medication prices in the United States are on average 2.56 times higher than in other OECD countries. AARP also found that the annual price increases of medications in the United States are continuing to rise at a rate higher than inflation.

With an estimated cost of $553.54 for a 30-day supply of Xiidra, people who suffer from dry eye disease and who do not have prescription drug insurance will need to continue paying a high price for this medication until the generic version is approved.

How do I save on Xiidra?

The high price for Xiidra can make treatment unaffordable for many people who suffer from dry eye disease. Fortunately, there are several options available to help you save money:

  1. Xiidra Savings Card – Novartis provides a savings coupon card to people who meet the eligibility requirements. If eligible, you can save on one fill-up to $250 per 30-day prescription or  $750 per 90-day prescription Check the terms and conditions on the Novartis website to determine if you are eligible as this offer may change.
  2. Patient assistance program – you might be eligible for enrollment into a patient assistance program for Xiidra.
  3. Ask your healthcare provider if they can provide free Xiidra samples – Novartis may provide your healthcare professional with Xiidra free samples that are intended for patients that need help getting started on the medication.
  4. Get medical advice from your prescribing healthcare provider and find out if there are any alternative medications that are right for you – find out from your doctor if there is a Xiidra alternative that can help with your condition.
  5. Shop around at mail-order pharmacies – prices by pharmacy may vary so it’s always best to shop around for the best possible price.
  6. Xiidra coupons – you may be able to find a Xiidra manufacturer coupon that can help you save more money.
  7. Help from Medicaid – find out if there is a state Medicaid plan available that will cover the cost of your Xiidra prescription.

Why is Trelegy so expensive?

Trelegy is a brand-name prescription drug used daily to treat COPD (chronic obstructive pulmonary disease) and asthma.

Trelegy is expensive because it’s a brand-name drug and there are no generic alternative versions available yet.

What is Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol)?

Trelegy Ellipta is a brand-name prescription inhaler medication manufactured by GlaxoSmithKline (GSK). It’s a combination of three drugs: fluticasone, umeclidinium, and vilanterol. Fluticasone is a corticosteroid. Umeclidinium is an anticholinergic. Vilanterol is a long-acting beta2-adrenergic agonist (LABA). Trelegy 100/62.5/25 mcg is the only strength that is approved for the treatment of COPD.

Trelegy is used to treat COPD (chronic obstructive pulmonary disease), including emphysema, chronic bronchitis, or both, and is also used for the treatment of asthma in adults. COPD is caused by damage to the lungs, usually from smoking. The damage can’t be reversed, but treatments can help manage the symptoms and slow the progression of the disease.

Trelegy Ellipta is not to be used as a rescue inhaler and should not be used to treat sudden breathing problems and bronchospasm (asthma attacks). It should not be used on children that are less than 18 years of age.

How does Trelegy work?

The three drugs in Trelegy work together to help improve breathing in people with COPD.

Fluticasone is a corticosteroid that works by reducing inflammation in the lungs.

Umeclidinium is an anticholinergic that works by relaxing the muscles around the airways and keeping them open.

Vilanterol trifenatate is a long-acting beta-agonist (LABA) that works by relaxing the muscles around the airways and keeping them open.

Side effects of Trelegy Ellipta

Common side effects of Trelegy Ellipta for COPD include:

  • upper respiratory tract infection
  • pneumonia
  • bronchitis
  • thrush in your mouth and throat
  • headache
  • back pain
  • joint pain
  • flu
  • inflammation of the sinuses
  • sore throat and runny nose
  • taste disturbance
  • constipation
  • painful and frequent urination (signs of a urinary tract infection)
  • nausea
  • vomiting
  • diarrhea
  • mouth and throat pain
  • cough
  • hoarseness

Common side effects of Trelegy Ellipta for asthma include:

  • runny nose and sore throat
  • upper respiratory tract infection
  • bronchitis
  • respiratory tract infection
  • inflammation of the sinuses
  • painful and frequent urination (signs of a urinary tract infection)
  • flu
  • headache
  • back pain

Trelegy Ellipta can also cause other serious side effects such as:

  • fungal infection in your throat (thrush) or mouth
  • pneumonia
  • weakened immune system and an increase in the chance of getting an infection
  • reduced adrenal function
  • sudden breathing problems immediately after inhaling the medication
  • serious allergic reactions
  • effects on heart – increased blood pressure, a fast or irregular heartbeat, awareness of heartbeat, chest pain.
  • effects on the nervous system  tremor; nervousness.
  • bone thinning or weakness (osteoporosis)
  • eye problems such as increased pressure in the eye, glaucoma, blurred vision, cataracts, worsening of narrow-angle glaucoma, or other possible changes in vision.
  • new or worse urinary retention
  • changes in laboratory blood values, including high levels of blood sugar (hyperglycemia) and low levels of potassium (hypokalemia).
  • slowed growth in children

Talk to your doctor about the risks and benefits of taking Trelegy Ellipta. Before starting to take Trelegy Ellipta, tell your healthcare professional about all of your medical conditions and any other prescription drugs including any other inhaled bronchodilators, over-the-counter, or supplements you are taking. Trelegy is a brand-name drug that’s not available in generic form. Trelegy is expensive, but there are some ways to save on the cost.

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How much does Trelegy cost?

Trelegy costs will vary depending on your health insurance plan and the coverage for this medication.

Once you and your plan spend the minimum required amount combined on drugs (including the deductible), you’ll pay no more than 25% of the cost for Myrbetriq, if this medication is covered under your health insurance company’s drug formulary.

For people without insurance who need to pay the cash price, the list price for a 30-day supply of Trelegy Ellipta is $619.92, according to the manufacturer.

For individuals with Medicare insurance coverage, around 61.4% of Trelegy prescriptions cost less than $50 per month, and the average cost of the remaining Trelegy prescriptions is $176 per month.

The manufacturer also estimates that for people who are insured through their employer or a private policy, around 51.6% of Trelegy prescriptions cost less than $20 per month, and the average cost of the remaining prescriptions is $113 per month.

No generic alternative to Trelegy is available

Trelegy is a brand-name prescription inhaler and there are currently no generic alternative of Trelegy available. Generic drugs are typically much less expensive than brand-name drugs.

The earliest date that Trelegy generic will become available is November 29, 2030, when the Trelegy patents expire. Individuals who suffer from COPD and asthma will need to purchase the brand-name product until the generic becomes available.

RELATED: Brand vs generic drugs

Patent laws

Patent laws for pharmaceutical discovery are designed to encourage innovation by giving drug companies a temporary monopoly on the market for new drugs that normally last around 20 years. This exclusivity period gives companies time to recoup their research and development costs before other manufacturers can produce generic versions of the drug.

However, pharmaceutical companies may also receive an extension on the patent protection by reformulating the medication, changing how to drug is administrated, or simplifying the dose, which is known as a “new use” or “new formulation” patent.

In the case of orphan drugs, the Orphan Drug Act provides pharmaceutical companies an additional seven years of patent protection for medications that are intended for rare diseases and affect 200,000 or fewer people in the United States.

When patents or other exclusive marketing rights expire, generic pharmaceutical manufacturers can submit an application to the FDA to produce a generic version of the drug. After the FDA approves a generic version of a drug, it may still take several months before the medication is available on the market. As multiple generic manufacturers will likely sell the generic version of the drug, competition will likely drive down the price of the medication making it more affordable for patients.

In the case of Trelegy, GlaxoSmithKline has received an extension on their patents for Trelegy through November 29, 2030 which means that there will likely be no generic versions of this medication available for sale until then.

Unregulated pricing for pharmaceuticals

In contrast to other developed nations, pharmaceutical pricing is not regulated by the United States government. This means that drug companies are free to set their own prices for medications without any regulation and oversight in the United States while the same medication may sell for significantly less in other countries.

According to a report by RAND, the cost of drugs in the United States is on average 2.56 times as high as in other developed OECD countries and annual price increases continue to rise faster than the rate of inflation, according to AARP.

With an estimated monthly cost of $619.92, according to the manufacturer, people who suffer from asthma and COPD will need to pay a high price for this medication until a generic alternative becomes available.

Alternatives to Trelegy Ellipta

Speak with your healthcare provider and find out if there are any Trelegy alternatives that are right for you. The most common alternatives of Trelegy are:

How do I save on Trelegy?

The high cost of Trelegy Ellipta can be a barrier for some people who are suffering from asthma or COPD. Fortunately, there are a few options available to help you save money:

  1. Trelegy Savings Coupon – the manufacturer of Trelegy, GSK, offers a savings coupon card to eligible individuals. You may be eligible to pay as little as $0 on your Trelegy prescription for up to 12 months. Check the terms and conditions on the GSK website to determine if you are eligible as this offer may change.
  2. Patient assistance program – you might be eligible for enrollment into a patient assistance program for Trelegy Ellipta.
  3. Ask your healthcare provider for free Trelegy samples – GSK provides healthcare professionals with free samples of its medication to provide to patients that need help getting started on the medication.
  4. Get medical advice from your prescribing healthcare provider and find out if there are any alternative medications that are right for you – find out from your healthcare provider if a lower-cost Trelegy alternative could work for you.
  5. Shop around at mail-order pharmacies for the best possible price – it’s possible to save money on Trelegy by shopping around for the lowest price at multiple mail-order pharmacies and local pharmacies as drug prices may vary by pharmacy.
  6. Trelegy coupons – you may be able to find a Trelegy manufacturer coupon from GSK to help you save money.
  7. Help from Medicaid – find out if there is a state Medicaid plan available that will cover the cost of your Trelegy prescription. Generally, these state Medicaid programs will have strict income requirements. The manufacturer states that most Medicaid patients will pay $4 to $9 per month for Trelegy.

 

Why is Myrbetriq so expensive?

Myrbetriq (mirabegron) is commonly used to treat overactive bladder in adults. It relaxes the muscles in the bladder to help decrease problems with urination. Myrbetriq is an expensive prescription drug with no generic alternative currently available.

There are several reasons why Myrbetriq is so expensive including patent laws that prohibit the sale of a generic alternative and unregulated pricing.

What is Myrbetriq (mirabegron)?

Myrbetriq is an expensive prescription drug, manufactured by Astellas, that is FDA (U.S. Food and Drug Administration) approved to treat overactive bladder symptoms of urgency, frequency, and leakage in adults. It is also approved for pediatric neurogenic detrusor overactivity (NDO) in children which is a type of bladder condition that is commonly caused by certain neurologic medical conditions.

Mirabegron is an adrenergic beta-3 receptor agonist that works by relaxing the bladder muscles to help decrease problems with urination.

Myrbetriq tablets are taken orally once daily with or without food, while the extended-release tablets are taken orally once daily with food.

Common side effects of Myrbetriq include high blood pressure, pain or swelling of the nose or throat (nasopharyngitis), urinary tract infection, dry mouth, dry eyes, constipation, and headache.

Before starting to take Myrbetriq, tell your doctor about all of your medical conditions including if you have liver or kidney problems, and any other prescription, over-the-counter, or supplements you are taking.

How much does Myrbetriq cost?

Myrbetriq costs will vary depending on your insurance plan’s coverage for this medication.

Once you and your plan spend the minimum required amount combined on drugs (including the deductible), you’ll pay no more than 25% of the cost for Myrbetriq, if this medication is covered under your health insurance company’s drug formulary.

For people without insurance who need to pay the cash price, Myrbetriq costs around $462 for a 30-day supply (30 tablets).

No generic alternative to Myrbetriq is available

Myrbetriq is a brand-name prescription drug and there is no generic alternative currently available.

A generic drug is an FDA-approved medication that contains the same active ingredients as the brand-name drug and is therapeutically equivalent. Generic drugs are typically much less expensive than brand-name drugs.

The earliest date that a generic for Myrbetriq could become available is 2025 when Mirabegron’s patents expire.

Patent laws

When a brand-name prescription medication is approved by the FDA, the pharmaceutical company that developed the drug is given patent protection. The patent protects the company’s investment in developing the drug by giving them exclusive rights to sell the drug for a certain number of years to recoup their research and development costs. The patent will generally last for around 20 years. After the patents expire, other companies can start selling generic versions of the drugs at lower prices.

In some cases, the pharmaceutical company will receive an extension on their patent protection period by reformulating a drug, for example, by simplifying the dosing or how the drug is administered. Extended-release versions of medications are one of the common ways pharmaceutical companies reformulate products. New methods of administering drugs may also mean taking a drug that was previously only available by nasal spray and creating an injectable version. Another example is dissolvable tablets that don’t need to be taken with water, which can also help the pharmaceutical manufacturer to extend patent protection as well. When a new use for a drug is discovered, the pharmaceutical company can be granted an additional three years of patent protection under FDA rules. The Orphan Drug Act also gives pharmaceutical companies an additional seven years of patent protection for drugs that are developed for rare diseases that affect 200,000 or fewer people in the United States.

After the patent expires, other companies are allowed to manufacture and sell generic alternatives. However, because Myrbetriq is a new drug, the patent has not yet expired. This means that there are no generic alternatives currently available on the market and therefore, no price competition for this drug. Unfortunately, people who are prescribed this expensive medication will need to pay the higher brand name price until a generic drug is approved for sale.

Myrbetriq’s patents are set to expire in 2025, so there will likely be a generic version available at that time.

Unregulated pricing

Unlike most other developed countries, prescription drug pricing is not regulated by the government in the United States. This means that drug companies can charge whatever they want for their products. This often leads to high prices for brand-name drugs like Myrbetriq.

NiceRx has performed a study on global drug pricing and there is conclusive data showing that Americans pay the highest prices in the world for brand-name medications.

With an estimated cost of around $462 for a supply of 30 tablets of Myrbetriq, people who suffer from overactive bladder will need to pay this higher price until a generic alternative becomes available for this medication.

No alternative medications for overactive bladder

In addition to the fact that there are no generic alternatives to Myrbetriq available yet, there is currently only one other similar drug which is approved for the treatment of overactive bladder. Gemtesa (vibegron) has a similar retail price to Myrbetriq so unfortunately, it is not a cost-saving alternative.

However, there is another classification of drugs called antimuscarinics (or anticholinergic) which are also prescribed to help treat overactive bladder (OAB) and urinary incontinence. These medications also relax the bladder muscles and are much less expensive. Examples of antimuscarinic medications include:

  • Vesicare (solifenacin)
  • Ditropan XL (oxybutynin ER)
  • Detrol (tolterodine)
  • Detrol LA (tolterodine ER)
  • Toviaz (fesoterodine).

What options are available to save on Myrbetriq?

The high cost of Myrbetriq can be a barrier for some people who need this medication. There are a few options available to save money:

  1. Myrbetriq Momentum Savings Card – the manufacturer of Myrbetriq, Astellas, offers a savings card to eligible individuals. If you are eligible, you can get your first prescription for free and save up to $70 per month for up to a full year. Check with the manufacturer for terms and conditions to determine if you are eligible as this offer may change.
  2. Patient assistance program – find out if you are eligible for enrollment into a patient assistance program for Myrbetriq.
  3. Ask your healthcare professional for free samples – Astellas provides healthcare providers with free samples to give to their patients to help people get started on the medication.
  4. Get medical advice from your prescribing healthcare provider and find out if an antimuscarinic medication can help with your overactive bladder – overactive bladder (OAB) and urinary incontinence are traditionally treated with another classification of drugs called antimuscarinics (or anticholinergic) which are much more affordable.
  5. Shop around for the best possible price – if you do not have insurance coverage or your copay for this medication is too high, shop around at different local pharmacies and mail-order pharmacies to try to find the best possible price. Drug prices vary by pharmacy. Some Medicare plans may help to cover the cost of this medication from mail-order pharmacies.
  6. Myrbetriq coupons – you may be able to find a Myrbetriq coupon to help you save on this medication.
  7. Consider getting help from Medicaid – most state Medicaid plans will cover Myrbetriq with a very low (or $0) copay. These state Medicaid programs will generally have strict income requirements.

What foods to avoid while on Saxenda

Saxenda is a once-daily injectable medication used to treat people who are overweight or obese with other weight-related medical problems. It belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists.

While there are no specific foods that you must avoid while on Saxenda, it is recommended to follow a low-calorie diet and increased physical activity.

What is Saxenda (liraglutide)?

Saxenda is an FDA-approved prescription injectable drug with the active ingredient liraglutide and is manufactured by Novo Nordisk. It helps people to lose weight and keep the weight off.

Chronic diseases like obesity usually require long-term treatment. Your doctor will help to create a specific plan that is customized to your weight-management goals.

Saxenda is not approved for the treatment of high cholesterol or high blood pressure.

How does Saxenda work?

Saxenda works by mimicking the hormone GLP-1 that your body naturally produces which is released after eating. GLP-1 signals the pancreas to produce insulin and also reduces hunger.

Saxenda addresses one of your body’s natural responses to weight loss. It works like GLP-1 by regulating your appetite, which may lead to eating fewer calories and losing weight.

Inject your dose of Saxenda under the skin in your stomach area (abdomen), upper arm, or upper leg (thigh), as instructed by your health care professional. Do not inject into a muscle or vein.

Saxenda is typically taken once a day at any time of day, without regard to the timing of your meals.

What are the most common side effects of Saxenda?

The most common side effects of Saxenda in adults are:

Nausea is known to be the most common side effect when starting Saxenda and decreases over time with most people as the body gets used to taking Saxenda. If you experience nausea while taking this medication, here are a few tips that may help:

  • eat low-fat, bland foods like tice, toast, and crackers
  • eat foods containing water such as soups and gelatin
  • avoid eating larger meals and instead eat smaller amounts more frequently (using smaller plates may help to reduce portion sizes)
  • take frequent sips of water
  • don’t lie down after finishing to eat
  • avoid wearing tight clothing
  • go outside for fresh air

There are also several known serious side effects of Saxenda which are less common:

  • increased risk of thyroid tumors
  • pancreatitis (inflammation of the pancreas)
  • severe hypoglycemia (low blood sugar levels)
  • increased heart rate
  • kidney problems (kidney failure)
  • gallbladder problems
  • anxiety
  • insomnia
  • serious allergic reactions
  • suicidal thoughts

Other serious side effects may happen while taking Saxenda such as thyroid tumors, including cancer. If you notice a lump or are swelling in your neck, have shortness of breath hoarseness or trouble swallowing, contact your healthcare professional for medical advice immediately as these are symptoms of thyroid cancer.

If you experience any of these side effects or experience an allergic reaction when taking Saxenda, call your healthcare professional or seek emergency medical attention right away.

What foods should I avoid while on Saxenda?

While there are no specific foods that you are required to avoid eating while on Saxenda, you should follow a healthy low-calorie diet plan as part of your treatment plan. You should also increase your physical activity and try to avoid:

  • processed foods
  • sugary drinks
  • fast food
  • alcohol
  • foods with high levels of salt
  • foods high in saturated and trans fats

If you have any questions about what foods to avoid while on Saxenda, talk to your healthcare professional or speak to a dietitian about setting up a diet plan that is right for you.

What are the best foods to eat with Saxenda?

While there are no specific foods that you need to eat with Saxenda, in general, you should eat a healthy low-calorie meal plan that includes:

  • fruit and vegetables
  • potatoes, bread, rice, pasta, and other starchy foods (wholegrain)
  • some meat, fish, eggs, beans, and other non-dairy sources of protein
  • some milk and dairy foods
  • small amounts of food and drinks that are high in fat and sugar

Who can take Saxenda?

Saxenda may help some adults who have excess weight and also weight-related medical conditions (such as high cholesterol, high blood pressure, or type 2 diabetes), or obesity, to lose weight and keep the excess weight off.

Saxenda is used in combination with a reduced-calorie diet and increased physical activity for chronic weight management in adults with a body mass index (BMI) of 30 kg/m2 or greater (obesity), in adults with a BMI of 27 kg/m2 or greater (overweight), and in children with obesity that are within the age 12-17 years with body weight that is above 132 pounds (60 kg).

You should not take Saxenda if you:

  • are under the age of 18
  • if you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • allergic to liraglutide or any of the ingredients in Saxenda
  • are pregnant or planning on becoming pregnant

Before you start taking Saxenda, tell your doctor about all of your medical conditions, including if you:

  • are taking any GLP-1 receptor agonist medicines
  • have or have had any problems with your pancreas, liver or kidneys
  • have severe problems with your abdomen, including slowed emptying of your stomach (gastroparesis) or if you have problems digesting food
  • have or have had suicidal thoughts, depression, or history of any mental health issues
  • are breastfeeding or planning to breastfeed.

Can I take Saxenda with other medications?

Saxenda is not approved for the treatment of type 2 diabetes and should not be used with any other GLP-1 receptor antagonists, insulin, or Victoza. Saxenda can be used with some other diabetes treatments. It is not known if it is effective and safe to use Saxenda with other prescription drugs, over-the-counter medications, supplements, or herbal products for weight loss. Speak with your doctor about any possible drug interactions with Saxenda and the other medications you are taking.

What foods to avoid when taking Creon

Creon is a prescription medication used to manage Exocrine Pancreatic Insufficiency (EPI). You may need to make changes to your diet and health when taking Creon as your pancreas won’t produce enough of the enzymes which are needed to properly break down the fats, proteins, and carbohydrates in your food, which may result in you not getting enough nutrients. With EPI, you will need to ensure that you are getting enough nutrients and vitamins, while at the same time avoiding foods that may irritate your digestive tract.

What is Creon (pancrelipase)?

Creon is the brand name of the prescription drug pancrelipase, manufactured by Abbvie Inc. It’s used to treat digestive problems caused by a lack of enzymes produced by the pancreas.

Pancrelipase is a mixture of three enzymes: lipase, protease, and amylase. These enzymes are normally produced by the pancreas and are necessary for the proper digestion of fats, proteins, and carbohydrates in food.

Creon is used to treat exocrine pancreatic insufficiency (EPI). This condition occurs when the pancreas doesn’t produce enough enzymes. Enzymes are needed to break down foods so that your body can absorb the nutrients. Without enough enzymes, you can develop malnutrition and other serious health problems.

Creon is also used to treat cystic fibrosis, a condition that affects the lungs and digestive system.

If you forget to take a dose of Creon, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not take two doses of Creon at the same time. This could cause an overdose and lead to serious side effects.

Take your medication as prescribed by your healthcare professional. Always take Creon capsules with snacks or meals and try to take the drug when you start your meal or snack. Always swallow the capsules whole with water or another liquid. Do not crush the Creon capsules. You can also open the capsule and mix the granules inside with a teaspoon of cold, soft, acidic food.

How does Creon work?

Creon works by replacing the natural digestive enzymes in their small intestine that are normally produced by the pancreas. These enzymes help your body break down and absorb fats, proteins, and carbohydrates from food.

Enzymes are proteins that act as catalysts in chemical reactions in the body. Lipase enzymes help break down fats, protease enzymes help break down proteins, and amylase enzymes help break down carbohydrates.

Creon is a mixture of these three types of enzymes. By replacing the missing enzymes, Creon helps your body digest food and absorb nutrients. Creon may promote weight gain and not weight loss.

Creon is available in different forms and strengths. The amount of enzymes in each form is different. Your doctor will prescribe the strength of Creon that’s right for you based on the severity of your condition and how well your body responds to the drug.

What are the most common side effects of Creon?

Creon can cause mild or serious side effects.

The most common side effects of Creon include:

  • increased blood sugar levels (hyperglycemia) or decreased blood sugar levels (hypoglycemia)
  • abdominal pain (stomach pain)
  • abnormal or frequent bowel movements
  • gas
  • vomiting
  • dizziness
  • sore throat
  • cough

Some people may also experience an allergic reaction to Creon. Symptoms of an allergic reaction may include:

  • hives
  • difficulty breathing
  • swelling of the face, lips, tongue, or throat

If you experience any of these side effects or experience an allergic reaction when taking Creon, call your doctor or seek emergency medical attention. Your doctor may be able to prescribe a different medication if medically appropriate for you.

What foods should I avoid with Creon?

You will need to make some changes to your diet when you’re taking Creon. Foods that are high in fat, protein, and carbohydrates can be difficult to digest and may make your symptoms worse.

Your doctor or a registered dietitian can help you create a balanced diet that includes the nutrients you need while avoiding foods that may irritate your digestive system.

In general, you should avoid:

  • fiber-rich foods – foods like lentils, peas, barley, and brown rice are known to be higher in fiber, and certain bread and carrots are known to be lower in fiber.
  • fried foods
  • processed meats
  • alcohol – multiple years of excessive alcohol use could increase your likelihood of EPI and pancreatitis
  • smoking
  • eating large meals – you should avoid eating large meals as it makes your digestive system work more than normal, and you are less likely to have uncomfortable symptoms of EPI if you eat 4 to 5 small meals per day, instead of having 3 large meals

You should also limit foods that are high in protein, such as red meat and beans. You should also avoid foods that are high in carbohydrates, such as bread, pasta, and sweets.

You may also need to avoid foods that are spicy, acidic, or high in fiber. These foods can irritate your digestive system and make your symptoms worse.

It’s important to talk to your doctor or dietitian about which foods you should avoid with Creon. They can help you create a balanced diet that meets your nutritional needs.

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What are the best foods to eat with Creon?

In general, you should eat a varied healthy diet that includes:

  • low-fat food
  • proteins
  • carbohydrates (carbs)
  • healthy fats such as monounsaturated fat, polyunsaturated fat, and omega-3 fatty acids
  • minimally processed foods
  • lean proteins such as turkey breast or chicken, egg whites, or tuna in water
  • drink plenty of fluids like fruit juices, broth and drinks without caffeine

Olive oil, peanut oil, seeds, nuts, and fish such as tuna and salmon, all contain healthy fats which are recommended to eat when taking Creon.

Instead of eating 3 large meals per day, it is recommended to eat several smaller meals per day with EPI.

Who can take Creon?

Creon is safe for most adults. However, it may not be suitable for people with certain medical conditions, such as diabetes or kidney disease.

Pregnant women and children should also avoid taking Creon.

If you have any concerns about whether Creon is right for you, talk to your doctor.

Can I take Creon with other medications?

Creon can interact with other medications, vitamins, supplements, or herbs you may be taking. A drug interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor should determine whether Creon is safe for you to take.

What foods to avoid with Trulicity

Trulicity is a prescription medication used to treat type 2 diabetes. While there are no specific foods that must be avoided with Trulicity, it is recommended to avoid certain foods and maintain a healthy diet to prevent or reduce unwanted side effects with this medication.

What is Trulicity?

Trulicity is the brand name for the prescription medication dulaglutide, manufactured by Lilly. Trulicity is in a class of medications that is known as glucagon-like peptide-1 GLP-1 receptor agonists. GLP-1 is a hormone that helps regulate blood glucose levels by increasing insulin production and decreasing glucagon secretion. Similar to Ozempic, Trulicity is used to help improve blood sugar levels in adults with type 2 diabetes. It is intended for the following uses in adults with type 2 diabetes:

  • to lower blood sugar levels
  • to reduce the risk of certain cardiovascular problems – people can use Trulicity to reduce the risk of stroke and heart attack and to lower the risk of death caused by a cardiovascular condition.

Trulicity is not insulin or a weight-loss drug. It is also not used for the treatment of type 1 diabetes.

Trulicity is injected under the skin (subcutaneous) once a week in the thigh, abdomen, or upper arm, and should be used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes. Do not inject into areas where the skin is tender, bruised, red, hard, thickened, or has scars or stretch marks. Do not use the same injection site twice in a row.

If you miss a dose of Trulicity, inject the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and inject your next dose at your regular injection time.

How does Trulicity work?

Trulicity works by mimicking the effects of GLP-1, a hormone that helps regulate blood sugar levels and tells your pancreas to release more of your own insulin. By increasing insulin production and decreasing glucagon secretion, Trulicity helps to keep blood sugar levels within a normal range.

Although Trulicity is not a weight-loss medication like Saxenda and Wegovy, people who take Trulicity may lose weight because of how the drug works in the body.

In a clinical study, people who had taken Trulicity for 26 weeks ended up losing 3 to 5 pounds. In comparison, people who had taken another diabetes medication called metformin only lost around 5 pounds. If you are taking Trulicity with any other diabetes medications, the amount of weight that you may lose could vary by the specific medications you are taking.

What are the side effects of Trulicity?

The most common side effects of Trulicity are:

  • nausea
  • diarrhea
  • vomiting
  • decreased appetite
  • abdominal pain
  • indigestion
  • fatigue

For people who have kidney problems – diarrhea, nausea,  and vomiting may cause dehydration (loss of fluids), which may cause kidney problems to worsen.

If you are experiencing nausea, speak with your doctor. You can also consider the following tips which you may find helpful:

  • eat smaller meals and try to split your daily meals into 4 or smaller meals
  • avoid fat or fatty foods
  • stop to eat when you feel full
  • try to eat bland foods like rice, crackers, or toast

Serious side effects of Trulicity may include:

  • inflamed pancreas (pancreatitis)
  • low blood sugar (hypoglycemia)
  • severe stomach problems
  • changes in vision

This is not a full list of all of the possible side effects of Trulicity. Get medical advice from your healthcare professional about how to recognize the side effects and what you can do to prevent or reduce them.

What is dumping syndrome?

Dumping syndrome is caused by rapid gastric emptying. Rapid gastric emptying is when food moves from your stomach into your duodenum too quickly. This causes symptoms such as nausea, diarrhea, light-headedness, or tiredness after eating or drinking.

What foods should I avoid with Trulicity?

While there are no foods that are known to interact with Trulicity which need to be avoided, some foods may make the side effects of Trulicity worse. If you experience any bothersome side effects after eating, try avoiding that food to see if your symptoms improve.

In general, it is recommended to eat a healthy diet when taking Trulicity or any other medication for diabetes. A healthy diet includes foods from all food groups and limits foods high in sugar, fat, and calories. Speak to your healthcare provider about what types of foods are best for you.

It is recommended to avoid foods and drinks that are high-fat, sugary, and calorie-dense, for example:

  • alcohol
  • fast food
  • junk food
  • processed food
  • soda
  • alcohol
  • cake
  • cookies
  • pastries
  • ice cream
  • chips
  • doughnuts
  • ‘healthy’ snacks like granola bars or fruit snacks that are actually high in sugar

You should also avoid drinking alcohol while taking Trulicity, as alcohol may cause both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) for those with diabetes, depending on the amount consumed. Most people with diabetes may enjoy a moderate amount of alcohol without adverse effects.

Can I drink caffeine with Trulicity?

Caffeine is safe to drink when using Trulicity, as there is no direct interaction between caffeine and Trulicity.

What happens if you eat too much on Trulicity?

Trulicity slows gastric emptying. If you have eaten too much while using Trulicity you will experience symptoms such as bloating, nausea, vomiting, and even stomach cramps.

What are the best foods to eat with Trulicity?

While there are no specific foods that you must eat with Trulicity, it is recommended to eat foods that are high in fiber and low in sugar, fat, and calories.

You should eat healthy foods like fruits, vegetables, whole grains, and other diabetes superfoods that are generally rich in fiber, antioxidants, minerals, and vitamins. In addition to the other health benefits, fiber is known for helping to lower your blood sugar levels and reducing the risk of heart disease.

Some examples of high-fiber food choices include:

  • green leafy vegetables – for example, spinach and collard greens, which are loaded with vitamins A, C, E, and K, calcium, potassium, and iron
  • sweet potatoes – filled with vitamin A and fiber, these root vegetables are also concentrated with vitamin C and potassium
  • tomatoes – low in carbohydrates (carbs), rich in vitamin C and E, and potassium
  • nuts – for example, walnuts and flax seeds, which are both excellent sources of healthy fats and omega-3 fatty acids that lower blood pressure and inflammation
  • salmon – people with diabetes are recommended by the American Diabetes Association to eat fish, primarily fatty fish, twice per week
  • low-fat dairy products – like milk and yogurt

Your healthcare professional or nutritionist can help you set up a meal plan that works best for you.

Who can take Trulicity?

Trulicity is for people with type 2 diabetes who are not able to control their blood sugar levels with diet and exercise alone. Trulicity should not be used to treat type 1 diabetes or diabetic ketoacidosis. Do not take Trulicity if you have a history of severe allergic reactions to dulaglutide.

Before taking Trulicity, tell your healthcare professional about all of your medical conditions, including if you:

  • have kidney problems
  • have liver problems
  • are pregnant or are planning to become pregnant as it is unknown if Trulicity can harm your unborn baby
  • are breastfeeding or planning to breastfeed as it is unknown if Trulicity can pass into your breast milk

Tell your healthcare professional about all of the medicines you take, including prescription and over-the-counter (OTC) medications, herbal supplements and vitamins. Taking Trulicity with other diabetes medicines may affect how well Trulicity or the other diabetes medicines work.

Can I take Trulicity with metformin and other medications?

Trulicity (dulaglutide) and metformin are safe to take together and are often prescribed to be used together for the treatment of type 2 diabetes and weight management.

Trulicity may interact with other medications, herbs, or vitamins you are taking. Be sure to speak with your healthcare provider about any possible drug interactions with any of the medications, herbs, and supplements you are taking, including:

  • insulin
  • oral diabetes medications
  • blood pressure medications
  • heartburn medications
  • steroids
  • birth control pills or patch

Switching from Adderall to Concerta

There are many types of ADHD medications that your doctor can prescribe including stimulants, non-stimulants, anti-depressants, blood pressure medications, and anticonvulsants. Clearly, there are many treatment options available and it can be puzzling when you are looking to change medication.

Stimulant meds are widely used and Adderall is one of the most well-known brand name drugs used to treat ADHD. Perhaps Adderall isn’t working well for you and your doctor has suggested trying Concerta but you are reluctant to start a new medication. This blog will take a look at how Adderall XR compares to Concerta so you are more informed when talking to your healthcare provider.

What is ADHD?

ADHD is the abbreviation of Attention Deficit Hyperactivity Disorder characterized by inattention, hyperactivity, and impulsivity. It is a neurodevelopmental disorder that is typically diagnosed in childhood, commonly in males but underdiagnosed in females. According to the Centers for Disease Control and Prevention, there are an estimated 6.4 million children and adolescents diagnosed with ADHD in the United States.

Mental health professionals have identified three types of ADHD, based on the main symptoms involved:

  • Inattentive type ADHD
  • Hyperactive-impulsive ADHD
  • Combination of inattentive and hyperactive-impulsive type ADHD

ADHD symptoms can vary from person to person, depending on the subtype of ADHD.

Inattentive type

Symptoms of inattention:

  • Disorganization
  • Struggle to pay close attention to details, which may result in frequent mistakes
  • Often does not follow through on instructions
  • Appear to not listen
  • Can get frustrated performing tasks or activities requiring mental effort
  • Distractibility
  • Misplace items
  • Careless mistakes
  • Forgetfulness
  • Daydreaming

Hyperactive/impulsive type

Symptoms of hyperactivity:

  • Behavior problems
  • Impulsive behaviors
  • Fidgeting with hands and feet or squirming
  • Trouble staying seated
  • Difficulty playing or doing leisure activities quietly
  • Excessive talkativeness, including interrupting in conversation
  • Difficulty waiting
  • Interrupt or intrude on others

Combination-type ADHD

The combined type of ADHD shows a mixture of inattentive and hyperactive/impulsive type symptoms and behaviors.

ADHD medication can reduce the troublesome symptoms of ADHD shown above. It is not an easy task to find the best ADHD medication. There are many factors that your doctor will consider when selecting a patient, including their history and genetics as well as the side effects they have experienced with other treatments or substances.

What is Adderall?

Adderall contains mixed amphetamine salts and is available in two formulations: Adderall IR (immediate-release) is short-acting and Adderall XR (extended-release) is long-acting. We will focus on Adderall XR in this blog as Concerta is an extended-release product only.

Adderall contains four different kinds of amphetamine salts – amphetamine sulfate, amphetamine aspartate, dextroamphetamine saccharate, and dextroamphetamine sulfate. It is a Schedule II controlled substance

Adderall XR is indicated for the treatment of:

  • Attention Deficit Hyperactivity Disorder (ADHD) in adults and children 6 years of age and older

What is Concerta?

Concerta is indicated for the treatment of:

  • Attention Deficit Hyperactivity Disorder (ADHD) in children 6 years of age and older, adolescents, and adults up to the age of 65

Concerta treats the symptoms of ADHD such as inattention, poor decision making, and poor impulse control. It can also be used for the treatment of narcolepsy.

Concerta is the brand name of an extended-release form of methylphenidate. Methylphenidate is a central nervous system (CNS) stimulant that is classed as a Schedule II controlled substance. It is a long-acting stimulant, therefore you only need to take Concerta once daily for symptom relief.

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How do Adderall XR and Concerta work in the body?

Adderall and Concerta belong to a class of drugs known as amphetamines. By working on the central nervous system, Adderall and Vyvanse increase activity in areas of the brain that help you with your concentration and behavior. They work specifically on the chemicals dopamine and norepinephrine in the brain. These neurotransmitters, dopamine, in particular, are involved in feelings of pleasure, focus, and finding things interesting. Stimulant medications reduce the symptoms of ADHD making conditions such as inattention, poor decision making, and poor impulse control much less of a daily problem.

Other prescription drug stimulants that work in a similar way include Ritalin (methylphenidate) and Vyvanse (lisdexamfetamine).

When is it recommended to switch From Adderall to Concerta?

  • When Adderall XR is not providing symptom control. It is possible your body may not be responding to the active ingredients in Adderall XR. Some people respond better to different stimulants and Concerta is another longer-acting stimulant to try. You need to find the drug that works best for you.
  • When Adderall is not well tolerated

Stimulants are powerful medications that wear off rapidly. They’re also completely eliminated from your body by the end of their specified duration, so it’s possible to stop taking them one day and start another stimulant on another. Your doctor will tell you how this transition should be made when changing from Adderall XR to Concerta.

How long does it take for Adderall XR to work?

It will take Adderall XR around 30 minutes to 1 hour to start working in your body for a duration of 10-12 hours. Duration times are just approximate.

How long does it take for Concerta to work in the body?

Concerta starts working in about 1 hour of taking the dose. Then, the drug is gradually released over time for a duration of 10-12 hours. Duration times are just approximate.

Forms and dosages of Adderall XR

Adderall XR (extended-release) is taken as a daily dose. It is available in capsule form in the following doses: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg. It is taken with or without food in the morning. Adderall XR capsules can be opened and mixed with food if required.

Doctors will usually prescribe a lower dose when you first start taking a medication and gradually titrate it until they find the right therapeutic dose for you and your symptoms.

Forms and dosages of Concerta

Concerta (extended-release) is taken as a daily dose available in tablet form in the following doses: 18 mg, 27 mg, 36 mg, and 54 mg.

In order for Concerta to work effectively, it needs to be taken whole. The tablet can not be crushed or chewed. It can be taken with or without food.

Adderall XR vs Concerta

  • Adderall XR contains four different kinds of amphetamine salts: amphetamine sulfate, amphetamine aspartate, dextroamphetamine saccharate, and dextroamphetamine sulfate. Concerta contains the active ingredient methylphenidate
  • Concerta is only available as an extended-release tablet whereas Adderall XR is available as an extended-release and immediate-release formulation
  • Concerta tablets can not be crushed or chewed due to their delivery system but Adderall XR capsules can be opened and added to food if needed
  • Both drugs have similar adverse effects including loss of appetite, trouble sleeping, and weight loss

Adderall XR and Concerta side effects

The most common side effects of Adderall XR and Concerta in children, adolescents, and/or adults with ADHD are:

  • Anorexia
  • Anxiety
  • Dizziness, nausea
  • Blurred vision
  • Dry mouth
  • Irritability
  • Insomnia
  • Upper abdominal pain, stomach pain, vomiting, loss of appetite, decreased weight, diarrhea, constipation
  • Motor tics (repeated muscle movements)
  • Increased heart rate

In rare instances, Adderall XR and Concerta can cause more serious side effects. These can include:

  • Serious cardiovascular reactions e.g. chest pain
  • Sudden death has been reported with CNS stimulant treatment at recommended doses in pediatric patients with structural heart defects or other serious heart problems
  • Sudden death, stroke, and heart attacks in adults
  • High blood pressure and increased heart rate
  • Suppression of growth – monitor height and weight in pediatric patients
  • Circulation problems – symptoms include skin color changes and a cold feeling including Raynaud’s phenomenon
  • Serotonin syndrome – an increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations
  • New or worsening psychosis, bipolar disorder, or mental health issues
  • Withdrawal symptoms if you suddenly stop using this medication – severe tiredness, sleep problems, mental/mood changes such as depression
  • Severe allergic reactions e.g. hives, shortness of breath

Your doctor will assess the benefits of using Adderall XR and Concerta against your risk of side effects. You are encouraged to report negative side effects or adverse reactions of Adderall XR and Concerta to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Controlled substances and dependence

The Controlled Substances Act in the United States categorizes Adderall XR and Concerta as Schedule II controlled substances meaning they have a high potential for abuse and dependence.

There are many dangers to taking amphetamines at high doses and for long periods of time. Physical dependence means you need the drug in order to feel normal, but stopping can lead to symptoms like anxiety, confusion and mood swings which could turn into something worse such as hallucinations. You are also at increased risk of overdose, brain damage, and death. Psychological dependence also poses risks including cravings so strong they’re difficult to control and become a drug addiction.

Signs of substance abuse or addiction in a loved one include dilated pupils, sweating, reduced appetite, insomnia, anxiety, hallucinations, and paranoia. More serious problems are an increased risk of overdose, brain damage, and death. Long-term effects of abuse can include addiction, heart problems, psychosis, paranoia, and seizures.

Non-stimulant options for treatment of ADHD

The long-acting stimulant formulations are the first-choice treatment for people with ADHD. These drugs are designed to maintain the effect of medication throughout your day, so you can alleviate symptoms throughout the day.

If you decide that you would like to stop taking Adderall XR and switch to Concerta, speak with your healthcare provider who will instruct you on the best way to do this.

Read the full prescribing information for Adderall XR and Concerta and always speak with your healthcare provider for medical advice about your medicine so they can monitor and evaluate your condition. Always inform your healthcare provider of all your medical conditions, and any medications you are taking, including over-the-counter meds and supplements.

Salary vs Health Insurance

Which states see most of their wages spent on health insurance? And how does this compare to other costs of living factors?

With the cost of living seemingly rising at an ever-increasing rate, people are paying more attention to their personal finances than ever before. Many of us are cutting back on non-essential spending and making tough choices to ensure we have enough money to cover the cost of daily life.

However, some things are unfortunately too important not to spend money on. These things include necessities such as food, rent, and of course, health insurance. After all, it’s often said that there’s nothing more important than your health, even with the often high price of prescription medication. If you are unable to afford your medication, NiceRx can help with over 1,500 FDA-approved medications including Xarelto, Eliquis, Creon and Opzelura.

While many of us benefit from generous workplace schemes that help to cover the cost of our insurance premiums, many others are not so lucky and have to meet high monthly payments to keep their policy intact. Of course, the benefits of being covered mean that in an emergency you can get access to treatment without having to pay full price, and you may have access to more affordable medication to treat ongoing conditions.

As health insurance is so important for safeguarding your wellbeing, as well as being such a large monthly expense for many people, we wanted to find out just how affordable it really is. We’ve pulled together data from a range of sources to see which states pay the most for their health insurance, and what proportion of their salary these policies eat up. We’ll also take a look at some of the large cost of living expenses to see how expensive health insurance is in comparison.

What proportion of your pay goes towards health insurance

Here we can see the average proportion of annual income that people in each state use to cover the cost of health insurance.

Pay towards health insurance

1.  West Virginia                         % of salary spent on health insurance: 20.85%

With an annual personal income per capita of $47,817 and an average cost of health insurance of $9,972, West Virginia sees the highest proportion of wages being spent on health insurance at a huge 20.85%. Even with the cover provided by these high premiums, West Virginians will still have to pay the difference for many treatments and prescription medications, making the total cost of maintaining good health even higher.

2. Louisiana                               % of salary spent on health insurance: 16.05%

Louisiana took second place, with the average salary being $54,435 while the average cost of health insurance in the state is $8,736. This amounts to 16.05% of the average salary being spent on health insurance.

3. Vermont                                 % of salary spent on health insurance: 15.28%

In third place is Vermont, where the cost of keeping up with your health insurance premiums could eat up 15.28% of your annual salary. With average annual salaries of $59,704 and health insurance costing $9,120, Vermonters are actually paying more for health insurance than those in Louisiana, though their higher wages make it a slightly smaller percentage.

 

How does the cost of health insurance compare to other major costs of living factors?

Health insurance is far from the only expensive cost of living factor that can put a strain on your personal finances, but how does it stack up against some of the others? We found the average income per capita across all 50 states to be $60,657.90 and used this to compare the average cost of a range of cost of living factors, finding out how much of this average salary they would use up.

 

Salary vs Insurance

 

Rent is by far the most expensive cost of living factor, soaking up 28.24% of the average American’s salary, with childcare costing the second-highest amount at 18.41%. Health insurance takes third place with an average cost of $6,487.20 which accounts for 10.69% of the average salary.

 

The proportion of annual salaries spent on rent across the country

As we just saw, rent is the most expensive cost of living factor, but where in the country spends the largest proportion of their salary just to keep a roof over their head?

 

Salary vs insurance rent

 

  1. Hawaii                                    % of salary spent on rent: 49.30%

Hawaii has the most unaffordable rent in the country with the annual cost reaching $29,772 compared to annual salaries of $60,389. This means Hawaiians are spending 49.30% of their salaries, virtually half of their earnings, just to cover the cost of rent.

 

The cost of childcare as a proportion of the average salary

For many people, the high cost of childcare will come as a surprise, but to the parents who have to cover this cost in order to get to work, it is an all too familiar reality.

 

Salary vs Insurance childcare

 

  1. Massachusetts                      % of salary spent on childcare: 25.36%

Parents in Massachusetts spend the largest proportion of their salary on childcare out of all 50 states. Despite having the highest average salary in the country at $82,475, the state still sees residents spending an average of 25.36% of their salaries on childcare, which costs over $20,000 a year!

 

How much is spent on food and beverage in each state?

Spending money on food and beverages is another necessary expense that contributes to the overall cost of living. It’s possibly the most non-negotiable expense as at the end of the day, we all must eat. Here’s how the cost of keeping yourself fed varies from state to state.

 

Salary vs Insurance food

 

  1. Maine                                      % of salary spent on food and beverage: 7.47%

People in Maine spend the highest proportion of their salaries on buying food and beverages. An average spend of $4,268.40 compared to an average personal income of $57,159 sees Mainers spending approximately 7.47% of their money on food and drinks.

 

Transportation costs by state compared to personal income

We all need to leave the house at some point or another, whether for work, to drop the kids off at school, or to do the weekly grocery shop. This makes transportation an important factor to consider when looking at the cost of living.

However, the cost of transport can vary wildly depending on whether you own your own vehicle or rely on transportation services like the bus or train to get around. To counter this, we have combined the amount spent on motor vehicles and parts in each state, with that spent on transportation services, allowing us to see which state pays the most to get around.

 

Salary vs Insurance transportation

 

  1. Montana                                 % of salary spent on transportation: 6.19%

Montana has the highest transportation costs in the country compared to the average income in the state, which stands at $56,672 per capita. Spending an average of $2,242.29 on motor vehicles and parts, with another $1,263.55 spent on transportation services, the total spent on transportation in the state is approximately $3,505.84 per person per year. This means Montanans spend 6.19% of their annual income just on transportation.

 

The states that spend the greatest portion of their salaries on clothing and footwear

Clothing and footwear are often forgotten about when considering the cost of living. Spending money on clothing is a necessity, with new clothes often required in different seasons, for new jobs, and especially for young children who quickly outgrow or wear out their clothes.

 

Salary vs Insurance clothing

 

  1. South Carolina                      % of salary spent on clothing and footwear: 2.22%

People in South Carolina spend the largest proportion of their income on clothing and footwear at 2.22%, based on an average income of $52,074 and a spend of $1,154.87. While much lower than many other costs of living factors, this is still a considerable expense that contributes significantly to the overall strain on people’s finances.

Methodology

We wanted to assess the cost and affordability of health insurance and other costs of living factors from state to state. To do this, we collected health insurance data from Value Penguin, data on personal income and the cost of food and beverages, transportation, and clothing and footwear from the Bureau of Economic Analysis. We also collected data for the cost of renting from a study by Patriot Software, and found data for the cost of childcare from World Population Review.

Once we had all of our data, we compared the annual cost of each factor to their personal income in each state. This allowed us to calculate what percentage of annual income is spent on each factor in the state, revealing just how affordable these factors are.

Vyvanse withdrawal or crash: symptoms, signs, timeline and treatment

Vyvanse is an FDA-approved brand name medication manufactured by Shire PLC containing the active ingredient lisdexamfetamine dimesylate, a derivative of amphetamine. It is an ADHD treatment (Attention Deficit Hyperactivity Disorder) primarily but also treats moderate to severe binge eating disorder. It is a prescription drug belonging to a class of drugs known as Central Nervous System stimulants but is also classed as a Schedule II controlled substance.

As a controlled substance Vyvanse can be used recreationally but unlike other amphetamines such as Adderall and Ritalin, it has less potential for abuse because it is slower acting and can’t be absorbed quicker if it’s crushed or ground up. Its prodrug formulation deters patients from seeking immediate stimulation by snorting but Vyvanse abuse can still occur.

Vyvanse is a prescription stimulant therefore when someone takes Vyvanse, as soon as the effects wear off, it is likely they will experience a crash. If they stop taking Vyvanse altogether, they may experience withdrawal symptoms. Let’s take a look at crash and withdrawal symptoms, signs, timelines, and treatment.

How does Vyvanse work?

By working on the central nervous system Vyvanse increases activity in areas of the brain that help you with your concentration, behavior, and energy levels. It works specifically on the brain chemicals dopamine and norepinephrine. Dopamine in particular is involved in allowing you to feel pleasure, focus, and find things interesting. Stimulant ADHD medications reduce the symptoms of ADHD such as inattention, poor decision making, and poor impulse control, to make the condition much less of a daily problem.

The most common side effects in adults taking Vyvanse are a decreased appetite, dry mouth, and trouble sleeping. More severe side effects of Vyvanse are cardiovascular problems, such as a fast heart rate, increased blood pressure, or in rare cases, chest pain or heart attack.

For Vyvanse to start working in your body, lisdexamfetamine must react with your blood and be converted into the active drug dextroamphetamine. Vyvanse is a prodrug, meaning it is converted from an inactive form into an active form in your body by chemicals or enzymes.

Vyvanse has less potential to be used recreationally than other amphetamines such as Adderall, Concerta, and Ritalin (methylphenidate), as it’s slower acting, and won’t be absorbed quicker if it’s crushed or ground up. The prodrug formulation deters patients from seeking immediate stimulation by snorting but Vyvanse abuse can still occur.

Vyvanse crash vs Vyvanse withdrawal

Withdrawal and crashes can both be difficult, but they differ greatly in their symptoms.

Withdrawals happen when someone stops taking Vyvanse; symptoms of withdrawal occur approximately 36 hours after the last dose.

Crash episodes typically come on more gradually over a longer period of usage and they’re also easier to manage if you notice them early on rather than waiting until it’s too late.

Vyvanse crash

When you start taking Vyvanse for the first time, your doctor may likely prescribe the lowest dosage possible for this medication. This helps minimize side effects as your body will adjust and an effective dose is determined based on how you respond. As the day progresses, there may be something called a “crash” which occurs in some people around lunchtime or early afternoon hours as the medication wears off; however it can also happen if doses are missed.

Symptoms of this crash can include anxiousness, tiredness, or feeling irritable. More often than not, people with ADHD will notice a return of their symptoms (as there is not enough drug in their system to manage the symptoms).

If you are experiencing problems with a Vyvanse crash, it is recommended that you do the following:

Take Vyvanse exactly as prescribed by your doctor. There is a risk of a much more severe crash when taking the medication at a dose higher than prescribed by your doctor, or when taking the medication in a method other than what is prescribed by your doctor, including injecting the medicine.

You should take your Vyvanse medication every morning at the same time. Taking Vyvanse regularly will help to regulate the levels of the medication in your body, and also help to avoid a crash.

Tell your healthcare provider if you are experiencing problems while taking the medication or if you regularly feel an afternoon crash. Your healthcare provider may decide to change the dosage of your Vyvanse to help with effectively managing your symptoms.

Vyvanse withdrawal timeline

Vyvanse withdrawal symptoms follow a specific timeline. Although there are specific factors that can change the length of time withdrawal lasts, there is a common timeline that you can expect:

The effects of Vyvanse will begin to set 24 hours after your last dose. You may experience depression, cravings for Vyvanse, increased appetite, sleeping for long stretches, and fatigue.

Withdrawal symptoms are more noticeable 3 -5 days into withdrawal when they reach their peak. Insomnia and mood swings may set in at this point.

Day 6 -7 side effects begin to dispel but some of the psychological symptoms like depression may continue if left untreated.

Factors that affect Vyvanse withdrawal

When Vyvanse is stopped abruptly, there is a sudden decrease in the amount of neurotransmitters such as dopamine and norepinephrine in your brain. This reduction produces withdrawal symptoms because the body is not accustomed to functioning at a lower level of stimulation.

There are some factors that may change how long a Vyvanse withdrawal can last, including:

  • Quitting method (tapering, medical detox, or cold turkey)
  • Frequency and dose use
  • How long Vyvanse was used
  • Mental health
  • Physical health complications
  • History of combining the medication with another substance

When an individual is aware that they are going to be reducing or stopping the use of Vyvanse, they can take certain steps to plan on reducing the symptoms of their comedown.

Some steps they can take include:

  • Do not use any additional stimulants, such as cigarettes or caffeinated drinks if you want to get enough quality rest and feel energized during the day without feeling exhausted from lack of energy.
  • Eat well. Staying hydrated and getting a good range of vitamins and nutrients can have a powerful effect on a person’s overall mood. Maintain an active lifestyle by engaging yourself throughout each day with productive activities like exercise which has been shown effective at improving both mental health as well physical wellness.
  • Create a plan for bedtime and establish an ideal sleeping environment. This includes creating the right kind of lighting in your room, and turning off all electronic devices at least two hours before sleep time so you don’t keep yourself awake with stimulating thoughts or light displays from devices like smartphones. They can disrupt our circadian rhythms which makes it difficult to fall asleep easily when we want to. You could also try adding some aromatherapy oils onto pillows such as lavender or jasmine to help you relax and drift off.
  • Keeping a schedule is important for managing stress. But when you are feeling overwhelmed with work or other obligations, it’s best to avoid planning anything that might make your anxiety worse. The best way to relieve stress is by finding an activity that you enjoy and can focus on. You may want to try deep breathing, meditation, or listening to music for some relaxing time.
  • Specific drugs and substances may be harmful to your sleep, so it’s best not to use them. These substances may further disturb a person’s sleep and extend the comedown. Alcohol is one such drug that can have dismissing effects on the body if consumed in large quantities or near bedtime.

Vyvanse dependence and withdrawal

Vyvanse is a stimulant medication and a controlled substance meaning it has a risk of dependence. Your healthcare provider will carefully monitor your use of this medication. Controlled substances are known to be habit-forming and may lead to drug abuse.

Stimulant drugs including Vyvanse when taken in large doses may cause a feeling of intense happiness or euphoria as well as more focus and alertness. Some people may misuse these medications to intensify these effects. However, misuse or overuse may lead to Vyvanse addiction and withdrawal symptoms.

Dependence

There are many dangers to taking amphetamines at higher doses and for longer periods of time. Physical dependence means you need the drug in order to feel normal, but stopping can lead to symptoms like anxiety, confusion, and mood swings which could turn into something worse such as hallucinations. You are also at increased risk of overdose, brain damage, and death. Psychological dependence also poses risks including cravings so strong they’re difficult to control and become a drug addiction.

Signs of Vyvanse abuse or addiction in a loved one include dilated pupils, sweating, reduced appetite, insomnia, anxiety, hallucinations, and paranoia. There are increased risks of overdosing, brain damage, or death. Long-term effects of abuse can include addiction, heart problems, psychosis, paranoia, and seizures.

A substance use disorder requires structured help and guidance from an inpatient treatment center or outpatient treatment program that specializes in substance abuse. Under the guidance of a medical professional, you can receive addiction treatment such as a detox program and other treatment options specifically suited to you. Consult your doctor for medical advice about Vyvanse detox programs and additional information can be found by visiting the American Addiction Centers’ article on the topic.

Withdrawal

Withdrawal symptoms can occur when stopping to take Vyvanse, even if you take Vyvanse exactly as the medication was prescribed and then you stop taking it suddenly. Withdrawal symptoms can include:

If you decide that you would like to stop taking Vyvanse, speak with your healthcare provider who may instruct you to slowly taper off the drug in order to help you with avoiding or reducing the withdrawal symptoms.  Vyvanse withdrawal is short-term and symptoms will likely fade after a few days; however, they could last for several weeks if you have been taking Vyvanse for a long period of time.

Read the full prescribing information for Vyvanse and always speak with your healthcare provider for medical advice about your medicine so they can monitor and evaluate your condition. Always inform your healthcare provider of all the medical conditions you have, and any medications you are taking including over-the-counter meds and supplements.

Jardiance alternatives: which other diabetes medication can I take?

Jardiance is used to control blood glucose levels and protect the heart in people with type 2 diabetes mellitus. It is often prescribed with other diabetes drugs such as metformin. It belongs to the drug class known as Sodium-Glucose coTransporter-2 inhibitors (SGLT-2 inhibitors).

Jardiance can cause adverse effects as all medications require dose adjustments in patients with kidney disease. If you are looking for alternatives to Jardiance it’s important to talk to a healthcare professional for medical advice and they will use the American Diabetes Association guidelines to make decisions on which medications may best for you. But here is a quick rundown on what is available to help kick start that discussion with your doctor.

What is Jardiance?

Jardiance is a medicine prescribed to adults with type 2 diabetes. It’s used to

  • Reduce blood sugar levels (when used alongside exercise and diet changes)
  • Reduce the risk of cardiovascular death in adults with type 2 diabetes and heart disease
  • Reduce the risk of cardiovascular death or hospitalization for heart failure in adults with heart failure and reduced ejection fraction

Jardiance can help you lower your blood sugar levels when taken alongside dietary and lifestyle changes. It causes you to excrete more sugar in your urine than you would normally. This lowers your blood sugar and helps to reduce your risk of health conditions like cardiovascular disease. Jardiance comes as a tablet you swallow with water.

Jardiance active ingredients

The active ingredient in Jardiance is called empagliflozin. It lowers your blood sugar levels by causing you to lose more sugar in your urine than you usually would.

Your kidneys normally help recycle sugar back into your blood from your urine, with the help of a protein called Sodium-Glucose coTransporter-2 (SGLT-2). Empagliflozin is an inhibitor of this protein, reducing how much sugar your kidneys recycle. This makes you lose more sugar in your urine, rather than it being absorbed back into your blood.

Side effects of Jardiance

As is the case with most medications, Jardiance side effects can occur. You might not experience any, but the most common side effects can include:

  • Genital yeast infections (thrush) in both men and women
  • Needing to urinate more often and urinating more than usual
  • Feeling more thirsty than usual
  • Joint pain
  • Weight loss
  • An increase in cholesterol levels

In rare instances, Jardiance can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • A rare but serious bacterial infection that damages tissue under the skin (necrotizing fasciitis) in the area between the anus and genitals (perineum)
  • Diabetic ketoacidosis, a potentially life-threatening condition where your body breaks down too much fat too quickly, causing you to produce high levels of blood acids called ketones
  • Hypoglycemia (low blood sugar) – particularly when used with other medications like insulin or sulfonylurea
  • An increased risk of serious urinary tract infections
  • A high and potentially harmful increase in your cholesterol levels
  • Dehydration
  • Low blood pressure

Jardiance drug interactions

Jardiance can also interact with other medications, which can limit its effectiveness, including:

  • Any other diabetes medications, like insulin or sulfonylureas
  • Other medications that can lower your blood sugar levels, like diuretics, corticosteroids, estrogens, oral contraceptives, nicotinic acid, and calcium channel blocking drugs

Jardiance warnings & precautions

Don’t take Jardiance if you:

  • Are allergic to the active ingredient empagliflozin
  • Are allergic to any of the other ingredients in Jardiance
  • Have type 1 diabetes
  • Are under 18 years of age

Talk to your doctor before taking Jardiance if you:

  • Have any liver or kidney problems
  • Have or have ever had problems with your pancreas, like pancreatitis or surgery on your pancreas
  • Have a history of urinary tract infections or any problems with urination
  • Often drink alcohol, or drink a lot of alcohol in a short period of time (“binge” drinking)
  • Are going to have surgery in the near future
  • Are eating less than usual or have changed your diet
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

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Alternatives to Jardiance

Januvia

Januvia belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It is a prescription medicine used to:

  • Treat type 2 diabetes, by helping to lower blood sugar levels when used in combination with exercise and changes to your diet

Januvia is taken as a pill that’s swallowed, usually once a day in the following doses: 25 mg, 50 mg, and 100 mg.

If you have type 2 diabetes, your body may not produce enough insulin or your body may become resistant to the effects of insulin. This means less sugar is removed from your blood and your blood sugar levels stay too high. High blood sugar levels can cause a range of problems over time, including nerve damage, heart disease, strokes, and kidney failure.

Januvia treats type 2 diabetes by helping to lower your blood sugar levels. It encourages your pancreas to continue producing insulin for longer after you’ve eaten, helping your body absorb more sugar out of your blood.

The active ingredient in Januvia is called sitagliptin. It works by increasing the amount of insulin you produce after you’ve eaten.

When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP. These hormones make your pancreas secrete insulin. As you continue to digest your food, the digestive hormones are broken down by an enzyme called DPP-4 to allow your levels of insulin to fall again.

Sitagliptin stops the DPP-4 enzyme from breaking down the digestive hormones. This keeps the hormones active for longer, making you produce more insulin, and lowering your blood sugar to normal levels.

Victoza

Victoza belongs to a class of drugs called glucagon-like peptide-1 agonists (GLP-1) and contains the active ingredient liraglutide. Victoza is injected under the skin and can be bought in easy-to-use self-injecting pen devices. It’s usually prescribed when people with type 2 diabetes can’t control their blood sugar through diet and exercise alone, or if their diabetes medication isn’t effective. Victoza can be used instead of other diabetes medicine, or alongside some diabetes medicines. This medication can also be used to reduce the risk of heart problems in people who have both type 2 diabetes and heart disease.

When you eat and digest food, sugar is released into your blood so it can be transported around your body. Your body absorbs the sugar out of your blood, returning your blood sugar to normal levels. In people with diabetes, their bodies struggle to control their blood sugar levels. Often their blood sugar is too high, and over time this can cause a range of problems, including nerve damage and heart disease. When injected, Victoza helps people with type 2 diabetes control their blood sugar levels in three ways:

  • It helps your pancreas produce more insulin
  • It reduces how quickly food moves through your stomach, slowing down the release of sugar into your blood
  • It helps to stop your liver from releasing too much sugar into your blood

Most diabetes treatments, especially ones you inject, are a type of insulin. Insulin is a natural hormone your body produces to help absorb sugar and control your blood sugar levels. However, Victoza isn’t a type of insulin. When injected, it causes your pancreas to naturally release more insulin if your blood sugar is high. As your blood sugar falls, the amount of insulin released reduces, until you’re back to a normal blood sugar level.

Trulicity

Trulicity is a brand-name drug manufactured by Eli Lilly. It belongs to the same drug class as Victoza. It is an FDA-approved prescription drug for adults who have type 2 diabetes. It helps to:

  • Reduce blood sugar levels, when used alongside exercise and dietary changes
  • Reduce the risk of serious heart problems, such as strokes or heart attacks in people with heart disease or in those who have risk factors for cardiovascular disease

If you have type 2 diabetes, you may not produce enough insulin, or you may even become resistant to insulin. If this happens, you will absorb less sugar from your blood, resulting in high blood sugar levels.

Trulicity can help you lower your blood glucose. It encourages your pancreas to secrete more insulin and reduces how much sugar is released into your blood. This can help to reduce your diabetes symptoms and the likelihood of developing other serious health conditions if taken alongside changes to your daily life like increasing exercise and having a healthier diet.

Trulicity is classed as a peptide-1 receptor agonist. The active ingredient dulaglutide is absorbed into your digestive system which has two effects. It binds with areas on some of your cells called glucagon-like peptide-1 (GLP-1) receptors. This encourages your pancreas to make more insulin, allowing cells in your body to more effectively remove sugar from your blood. At the same time, dulaglutide also reduces how much sugar your pancreas allows to be released into your blood. The combination of these two processes can reduce your blood sugar levels.

Byetta

Byetta is from the same drug class as Trulicity and Victoza. It is an injectable prescription medication given to adults with type 2 diabetes. It can help to lower blood glucose levels when taken alongside exercise and dietary changes. You take Byetta by injecting it under your skin (subcutaneous injection) using a pre-filled, self-injecting pen, usually twice a day before your two main meals.

Byetta works by encouraging your pancreas to produce more insulin and reducing how much glucose your liver secretes into your blood. Byetta does this while you are digesting food, helping to stop your blood glucose from rising too high when you most need it. Byetta becomes less active when you stop digesting and your blood glucose falls, helping to stop your blood sugar from falling too low (hypoglycemia).

The active ingredient in Byetta is called exenatide. It is a type of drug called an incretin mimetic that mimics digestive hormones, called incretins, that your body releases when you digest food. Exenatide works by having the same effects on your body as incretin digestive hormones. When you are digesting food and glucose is released into your blood, exenatide encourages:

  1. Your pancreas to produce more insulin
  2. Your pancreas to produce less of a hormone called glucagon that makes your liver release stored glucose into your blood
  3. Food to move more slowly through your digestive system, causing glucose to be released from your food slower

These three effects can cause your blood glucose levels to fall as you are digesting food. Exenatide stops being as active when you are not digesting food, which can help stop your blood glucose levels from falling too low.

There is also evidence that exenatide can reduce your appetite, helping you lose weight gradually as you use it, and that it can lower your cholesterol levels over time too. This can also help treat your type 2 diabetes.

Invokana

Invokana is from the same class of drugs as Jardiance so will work in a similar way. It is a medication used to treat type 2 diabetes. It’s usually prescribed together with exercise and dietary changes to help manage blood sugar levels. Invokana helps with type 2 diabetes by increasing the amount of sugar that’s removed from your body in your urine. This helps to keep your blood sugar levels lower. Invokana is taken orally as a tablet swallowed with water.

The active ingredient in Invokana is called canagliflozin. It helps to lower your blood sugar by blocking a process in your body that reabsorbs sugar from your urine. This increases the amount of sugar in your urine and causes you to lose more than you would normally do when you urinate. Used alongside exercise and improvements in your diet, and sometimes other diabetes medications, canagliflozin can help you maintain a lower blood sugar level.

Glucophage (Metformin)

Metformin is a diabetes medication belonging to the drug class called biguanides. Metformin helps to reduce or control the amount of sugar in your blood. It can help with weight loss, while nearly all other diabetes drugs cause weight gain. It is especially useful for diabetic patients struggling with obesity.

Metformin is given to adults and children 10 years of age or older, diagnosed with Type 2 diabetes mellitus to:

  • Increase glycemic control as an adjunct to diet and exercise

Metformin is an oral medication taken as a liquid, tablet, or extended-release tablet.

The liquid form is usually taken with meals one or two times a day. The regular tablet is usually taken with meals two or three times a day. The extended-release tablet is usually taken once daily with the evening meal.

The tablets are available in five strengths:

  • 500 mg, 625 mg, 750mg, 850mg and 1000mg

The recommended starting dose of Metformin hydrochloride tablets is 500 mg orally twice a day or 850 mg once a day, given with meals. Your healthcare provider will advise you on what dosing regime is suitable for you.

Metformin works in three ways:

  • It reduces the amount of glucose absorption from your food
  • It reduces the amount of glucose made by your liver
  • It increases your body’s response to insulin

Metformin is a very useful drug in that it reduces high blood sugar but does not cause hypoglycemia in patients with type 2 diabetes who are not taking insulin injections. It can do this because it does not increase your insulin production like many other diabetes medications.

Is there a cheaper alternative to Jardiance?

While there is no generic Jardiance currently available in the United States at this time, there are other cheaper alternatives to Jardiance that have generic equivalents available, including Glucophage (metformin), Starlix (nateglinide), Glyset (miglitol), Precose (acarbose), Glucotrol XL (glipizide extended release). Speak with your doctor to determine if any of these alternatives are medically appropriate for you.

Final word

Treatment of type 2 diabetes can be overwhelming as there are so many medications and combinations of medications available. Other alternatives to Jardiance include Tradjenta (linagliptin), Farxiga (dapagliflozin), Actos (pioglitazone), Glucotrol (glipizide), and Onglyza (saxagliptin) Your doctor can provide you with more information. Always inform your healthcare provider of your medical conditions, and any medications you are taking including over-the-counter meds and supplements.

What foods to avoid while on Eliquis

Eliquis is an anticoagulant medication used to prevent and treat blood clots. It is important to avoid foods such as grapefruit and other medications that can increase your risk of bleeding while taking this medication.

What is Eliquis?

Eliquis is the brand name for the medication apixaban, manufactured by Bristol-Myers Squibb and Pfizer. It is an FDA-approved prescription medication that is part of a class of medicines called anticoagulants and is used to prevent blood clots that can cause a stroke or heart attack. Eliquis works by inhibiting the activity of certain clotting proteins in the blood. This action helps to reduce the risk of blood clots, strokes, and other serious cardiovascular events.

Eliquis is used for a variety of medical conditions in adults including:

  • to prevent a blood clot from forming in the heart of people with an irregular heartbeat (atrial fibrillation) and at least one additional risk factor.
  • to treat blood clots in the veins of your legs (deep vein thrombosis) and in the blood vessels of your lungs (pulmonary embolism), and to prevent blood clots from re-occurring in the blood vessels of your legs and/or lungs.

How does Eliquis work?

Eliquis helps to prevent blood clots by:

  • inhibiting the activity of certain clotting proteins
  • reducing the risk of blood clots, strokes, and other serious cardiovascular events.

Eliquis is typically taken twice daily. The risk of bleeding may be increased when Eliquis is taken with certain other medications, such as aspirin or other blood thinners. It is important to avoid foods that can increase your risk of bleeding while taking this medication.

If you miss a dose of Eliquis, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Eliquis at the same time.

What are the side effects of Eliquis?

Eliquis can cause mild to severe side effects. The most common mild side effects of Eliquis include:

  • bleeding
  • bruising more easily than usual
  • fatigue
  • anemia (low level of red blood cells)

More serious side effects include:

  • allergic reaction
  • bleeding
  • increased risk for blood clots if you stop taking Eliquis early
  • blood clots in your spine with spinal procedures

New oral anticoagulants (Pradaxa, Eliquis, Xarelto) are not affected by vitamin K and do not have these dietary restrictions.  Vitamin K is a nutrient found in high amounts in spinach, kale, and collard greens.

Eliquis comes with a black box warning. A black box warning is the most serious type of warning issued by the U.S. Food and Drug Administration (FDA). It alerts doctors and patients about potential risks associated with a medication.

Eliquis may also interact with certain medications and foods. It is important to avoid foods and drinks that can increase your risk of bleeding while taking this medication.

If you are taking Eliquis, it is important to speak with your doctor or pharmacist about all of the prescription medications, over-the-counter medications, vitamins and supplements you are taking.

What foods should I avoid while taking Eliquis?

You should avoid eating grapefruit or drinking grapefruit juice unless your doctor instructs otherwise. Talk to your doctor about other foods that may interact with Eliquis and increase your risk of bleeding.

Eliquis is not known to interact with coffee and green leafy vegetables that are known to contain high levels of vitamin K which can affect a different anticoagulant called warfarin (Coumadin and Jantoven) that needs your body to keep a balance between the amounts of vitamin K and warfarin in your system.

What are the best foods to eat while taking Eliquis?

There are no specific foods that you need to eat while taking Eliquis, but eating a healthy and balanced diet is always important. A healthy diet includes:

  • fruits and vegetables
  • whole grains
  • lean protein
  • low-fat dairy

Eating a healthy diet can help you manage your weight, blood pressure, and cholesterol. This can in turn reduce your risk of developing heart disease, stroke, and other conditions.

If you have any questions about what to eat while taking Eliquis, talk to your doctor or dietitian. They can help you create a healthy eating plan that is right for you.

Who can take Eliquis?

Eliquis is a prescription medication that is used to prevent blood clots from forming in people who have atrial fibrillation (a heart condition that causes an irregular heartbeat) and are also at risk for developing a blood clot. Eliquis is also used for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE).

Eliquis should be taken exactly as prescribed by your doctor. This prescription drug is not suitable for some people. To make sure it’s safe for you, tell your healthcare professional if you:

  • have ever had an allergic reaction to apixaban or any other medicine
  • are trying to get pregnant or are already pregnant
  • have kidney or liver problems
  • have had a recent surgery or spinal injury
  • have any injuries that are currently bleeding a lot such as a wound
  • have a stomach ulcer
  • have antiphospholipid syndrome
  • have ever had surgery to replace a heart valve

It is important to tell your doctor about all other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with Eliquis. Eliquis may also interact with other medications used to treat atrial fibrillation (Afib) or DVT/PE.

Can I take Eliquis with other medications?

Yes, you can take Eliquis with other medications. However, you should speak to your healthcare provider about all other prescription medications, over-the-counter medications, vitamins, and supplements that you are taking, as there may be drug interactions. In particular, you should avoid taking Eliquis with aspirin or other blood thinners, as this may increase your risk of bleeding. Examples of other anticoagulant medications include:

You should also avoid taking Eliquis with non-steroidal anti-inflammatory drugs (NSAIDs), as this may also increase your risk of bleeding.

What foods to avoid while taking Ozempic

Ozempic is a medication used to treat type 2 diabetes and consuming some types of foods may contribute to raising your blood sugar levels. While there are no specific foods that are strictly prohibited while taking Ozempic, it is recommended to avoid certain foods, including those high in fat, sugar, and calories.

What is Ozempic?

Ozempic is the brand name for the medication semaglutide manufactured by Novo Nordisk. It is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist. Ozempic is FDA-approved to treat type 2 diabetes and can help control blood sugar levels. Ozempic has also been linked with weight loss in some people. Ozempic can lower blood glucose levels in type 2 diabetes. It may also lower the risks of kidney and heart disorders.

Ozempic helps control your blood glucose levels by imitating the effects of GLP-1 naturally produced in our bodies. If you have type 2 diabetes and are overweight or living with obesity, it’s possible that this hormone may not be as effective for normalizing glycemic regulation. Blood glucose levels are more easily controlled when injecting Ozempic once weekly under the care of a healthcare professional.

Ozempic is typically taken once a week, at any time of day. You can take it with or without food.

If you miss a dose of Ozempic, you can take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular dosing schedule. Do not take two doses of Ozempic in one day.

How does Ozempic work?

Ozempic works by mimicking the effects of a hormone called GLP-1. This hormone is released after eating, and it signals to the pancreas to release insulin which then helps to lower blood sugar levels. Ozempic works by increasing the amount of GLP-1 in the body, which leads to more insulin being released and blood sugar levels being lowered.

Similar to other GLP-1 medications, including Wegovy, Rybelsus, and Saxenda – Ozempic is a prescription drug that helps with losing weight. However, Ozempic doesn’t cause weight loss on its own. It should be taken while performing other actions that will avoid weight regain and support metabolic health. These actions may include changes to what you are eating and sticking to healthy eating habits, when and how you are exercising, and making other healthy lifestyle changes.

What are the side effects of Ozempic?

Most people who take Ozempic will experience few side effects.

The most common side effects of Ozempic include:

Other possible Ozempic side effects include:

  • headaches
  • low blood sugar levels
  • weight loss

Some people taking Ozempic have reported kidney problems, such as kidney failure, as an uncommon side effect.

Ozempic is associated with a higher rate of diabetic retinopathy compared to other types of medications. This can lead not only to poor vision but also to complications like nerve damage and heart disease in some cases.

Ozempic can also cause an allergic reaction in some people, such as rash, itchiness, and flushing (swelling, warmth, or redness in your skin). In some rare cases, Ozempic may also cause serious allergic reactions such as swelling under your skin, most commonly in your lips, eyelids, hands, or feet, and swelling of your mouth, tongue, or throat which can make it difficult to breathe.

You should speak with your healthcare provider if you experience any side effects or allergic reactions while taking Ozempic.

Do some foods make the side effects of Ozempic worse?

Yes, some foods can make the side effects of Ozempic worse. These include high-fat foods, sugary foods, and alcoholic beverages. Eating these types of foods can also raise your blood sugar levels.

The most common side effects reported by people who take Ozempic are nausea and mild stomach pain. Fortunately, you can prevent or reduce these side effects by taking care of what you eat.

Fatty and fried foods, for example, fast food, and foods that are high in sugar, are usually the most difficult for the body to digest and will most likely cause nausea while taking a GLP-1 prescription medication.

According to the manufacturer, Novo Nordisk, people who are taking Ozempic and experience nausea should consider doing the following:

  • Eat slowly
  • Eat smaller meals
  • Eat foods that are bland and light
  • Drink ice-cold or clear drinks (for example, unsweetened tea or water)
  • Avoid foods that are sweet, greasy, or fried

What foods should I avoid while taking Ozempic?

There are no specific foods that you need to avoid while taking Ozempic however it is recommended to watch what you eat while taking this medication to prevent or reduce the potential side effects while taking this medication. Avoid foods that are high-fat, sugary, and calorie-dense, for example:

  • fast food
  • junk food
  • processed food
  • soda
  • alcohol
  • cake
  • cookies
  • pastries
  • ice cream
  • chips
  • doughnuts
  • ‘healthy’ snacks like granola bars or fruit snacks that are actually high in sugar

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What are the best foods to eat while taking Ozempic?

There are no specific foods that you need to eat while taking Ozempic. However, it is generally recommended to eat a healthy diet that is low in fat, sugar, and calories in order to prevent high blood sugar. This type of Ozempic diet can help you control your blood sugar levels and lose weight. Focus on meal plans that include eating healthy foods that can raise your blood sugar levels like:

  • fruits – such as apples, oranges, bananas, and grapes.
  • vegetables – such as broccoli, carrots, and spinach.
  • whole grains – carbohydrates such as oatmeal, whole wheat bread, and brown rice, which are nutrients that turn into blood sugar.
  • legumes – such as beans, and lentils.
  • lean protein – such as chicken, fish, tofu, and beans.
  • healthy fats – such as olive oil, avocados, nuts, and seeds that may help to reduce your risk of a cardiovascular event, including stroke and heart attack.

Who can take Ozempic?

Ozempic is typically prescribed to adults with type 2 diabetes. It is not typically prescribed to children or people with type 1 diabetes. If you have a history of pancreatitis, you should not take Ozempic. Do not take Ozempic if you are pregnant or breastfeeding. Ozempic may not be the right diabetes medication for you if you have certain medical conditions or other risk factors that may affect your health. Talk with your doctor about your health history before taking Ozempic.

For individuals with diabetes, it is important to monitor low blood sugar to prevent symptoms of hypoglycemia (low blood sugar).

There is a possibility that Ozempic may cause thyroid cancer. You should not take Ozempic if you have a history of a thyroid tumor or thyroid cancer.

Can I take Ozempic with metformin?

Ozempic and metformin are safe to take together and are often prescribed together for the treatment of type 2 diabetes and weight management.

Speak to your healthcare provider if you are taking any other prescription medications, over-the-counter medications, or supplements while taking Ozempic.

Switching from Adderall to Vyvanse

Patients receiving treatment for attention deficit hyperactivity disorder (ADHD) often need to change their medication. Switching medication is often recommended by healthcare professionals when ADHD symptoms are not controlled or there are unacceptable adverse effects. There are many ADHD medication treatment options to consider. How and when to switch medications should be done under your doctor’s medical advice and guidance. Several questions arise when changing medications and this blog will focus on switching from Adderall to Vyvanse.

What is Adderall?

Adderall contains mixed amphetamine salts and is available in two formulations: Adderall IR (immediate-release) is short-acting and Adderall XR (extended-release) is long-acting. We will focus on Adderall IR in this blog.

Adderall contains four different kinds of amphetamine salts – amphetamine sulfate, amphetamine aspartate, dextroamphetamine saccharate, and dextroamphetamine sulfate.

Adderall IR is indicated for the treatment of:

  • Attention Deficit Hyperactivity Disorder (ADHD) in adults and children over 6 years old
  • Narcolepsy

What is Vyvanse?

Vyvanse is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire PLC. Vyvanse is the brand name of lisdexamfetamine dimesylate, a derivative of amphetamine. Vyvanse contains the prodrug lisdexamfetamine, which is metabolized into L- lysine, and dextroamphetamine once it is in the body.

It is a prescription drug belonging to a class of drugs known as Central Nervous System stimulants.

Vyvanse is used to treat:

  • ADHD in adults, adolescents, and children over the age of 6 years
  • Moderate to severe binge eating disorder

Vyvanse is not recommended for weight loss and obesity. Vyvanse is a prescription stimulant medication but is also classed as a Schedule II controlled substance. As a controlled substance, doctors usually prescribe small doses.

Other drugs included in the class of Central Nervous System stimulants include Concerta (methylphenidate), and Ritalin.

How do Adderall and Vyvanse work in the body?

Adderall and Vyvanse belong to a class of drugs known as amphetamines. By working on the central nervous system Adderall and Vyvanse increase activity in areas of the brain that help you with your concentration and behavior. They work specifically on the chemicals dopamine and norepinephrine in the brain. These neurotransmitters, dopamine, in particular, are involved in feelings of pleasure, focus, and finding things interesting. Stimulant medications reduce the symptoms of ADHD making conditions such as inattention, poor decision making, and poor impulse control much less of a daily problem.

One important difference is that Vyvanse is a prodrug, meaning lisdexamfetamine is converted into dextroamphetamine once it is in the body. Vyvanse remains inactive until the body breaks it down in the bloodstream. This is not the case with Adderall.

How long does it take for Vyvanse to work?

It will take about 1 to 3 hours for Vyvanse to work when taken on an empty stomach to reach its maximum level in your blood. If a Vyvanse chewable tablet is taken on an empty stomach it will take slightly longer to kick in. Vyvanse can provide a much more steady experience due to the slower speed of absorption.

It is important to remember these timings are rough estimates because several factors need to be taken into consideration such as drug tolerance, weight, height, and sleep patterns to name a few.

For Vyvanse to start working in your body, lisdexamfetamine must react with your blood and be converted into the active drug dextroamphetamine. Vyvanse is a prodrug, meaning it is converted from an inactive form into an active form in your body by chemicals or enzymes.

Forms and dosages of Vyvanse

The recommended starting dose of Vyvanse is 30 mg. Your doctor may periodically increase or decrease your dosage to help control ADHD symptoms and manage any side effects. You’ll work with your doctor to find an ADHD dose that’s best for you.

Vyvanse is a available in chewable tablet form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg & 60 mg.

Vyvanse is also available in capsule form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg & 70 mg.

How long does it take for Adderall to work?

It will take Adderall around 30 minutes to 1 hour to start working in your body, therefore having a faster absorption rate than Vyvanse. You can experience increased energy and focus quicker, which may be useful if you need immediate relief from ADHD symptoms. Just like Vyvanse, these duration times are just approximate.

Forms and dosages of Adderall

Adderall IR is available in tablet form in the following doses: 5mg, 7.5mg, 10mg, 12.5mg, 20mg and 30 mg.

Doctors will usually prescribe a lower dose when you first start taking a medication and gradually titrate it until they find the right therapeutic dose for you and your symptoms.

Adderall vs Vyvanse

Adderall is a similar medication to Vyvanse. Both are central nervous system stimulants derived from amphetamines, and both are used for the treatment of ADHD. Vyvanse is also used for the treatment of binge eating disorders (BED), but Adderall isn’t.

Although the two medications are similar and work in a similar way, they contain different active ingredients. Adderall contains four different kinds of amphetamine salts, whereas Vyvanse only contains lisdexamfetamine, which is converted to dextroamphetamine inside your body.

Both Vyvanse and Adderall are effective treatments for ADHD, and they both cause similar side effects. Vyvanse only has an effect once it’s been converted into your body. It’s thought to have a lower risk of substance abuse than Adderall because it’s manufactured to have a slower rate of chemical release and requires enzymes in your body to convert it into its active form.

Vyvanse metabolizes slowly, allowing it to work longer than Adderall. Adderall metabolizes quickly and is absorbed through the gastrointestinal tract. Differences are seen in the onset of action time. Vyvanse takes around 1 to 3 hours to work depending on the formulation and its effects last up to 14 hours when taken once daily. Adderall is normally prescribed twice daily, it takes about 30 minutes to 1 hour to work, and its effects last 4 to 5 hours.

When is it recommended to switch From Adderall to Vyvanse?

  • When Adderall is not providing symptom control over the course of the day and Vyvanse is more appropriate as it is longer acting
  • Taking Adderall twice a day is not convenient and once-daily Vyvanse is better for you
  • You may be diagnosed with binge eating disorder and Adderall can not be used. so a switch to Vyvanse is needed to treat both ADHD and binge eating disorder

Stimulants are powerful medications that wear off rapidly. They’re also completely eliminated from your body by the end of their specified duration, so it’s possible to stop taking them one day and start another stimulant on another occasion. Your doctor will tell you how this transition should be made when changing from Adderall to Vyvanse.

Are Adderall and Vyvanse safe to use?

Lisdexamfetamine, the active ingredient in Vyvanse, is a controlled substance that can be abused and become habit-forming. Vyvanse has the potential to be addictive. However, when used as prescribed to treat a medical condition, Vyvanse shouldn’t become habit-forming.

Lisdexamfetamine is converted in your body into dextroamphetamine, which is an amphetamine. Amphetamines can be used as a recreational drug. This is where they aren’t used as prescribed or to treat an indicated medical condition.

Recreational use, particularly heavy use of amphetamines, can lead to physical dependence (addiction). It can alter the way your body works. You can also become more tolerant of them, requiring higher doses to get the desired effect.

Vyvanse has less potential to be used recreationally than other amphetamines, as it’s slower acting, and won’t be absorbed quicker if it’s crushed or ground up. If used as directed by a doctor to treat ADHD or BED, it shouldn’t become addictive. Research has also shown that long-term use of stimulants from childhood to treat conditions like ADHD reduces the chances of addiction. Your healthcare provider should assess your risk of Vyvanse addiction before prescribing and should monitor you while you take it.

Adderall in contrast has more potential to be addictive as it is faster acting than Vyvanse and will be absorbed quicker. Because it works quickly when crushed up and used it may have a higher potential for misuse.

Vyvanse and Adderall are Schedule II drugs, which means there is a potential for abuse and dependency. Since Vyvanse needs to be converted in the body, it can’t be inhaled or injected as a way to become high, so it is less likely to be misused than Adderall and other stimulant medications. Always store your medications safely and away from other people.

Adderall and Vyvanse side effects

The most common side effects of Adderall and Vyvanse in children, adolescents, and/or adults with ADHD are:

  • Anorexia
  • Anxiety
  • Dizziness, nausea
  • Blurred vision
  • Dry mouth
  • Irritability
  • Insomnia
  • Upper abdominal pain, stomach pain, vomiting, loss of appetite, decreased weight, diarrhea, constipation
  • Motor tics (repeated muscle movements)
  • Increased heart rate

In rare instances, Adderall and Vyvanse can cause more serious side effects. These can include:

  • Serious cardiovascular reactions e.g. chest pain
  • Sudden death has been reported with CNS stimulant treatment at recommended doses in pediatric patients with structural heart defects or other serious heart problems
  • Sudden death, stroke, and heart attacks in adults
  • High blood pressure and increase in heart rate
  • Suppression of growth – monitor height and weight in pediatric patients
  • Circulation problems, such as skin color changes, a cold feeling including Raynaud’s phenomenon
  • Serotonin syndrome – an increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations
  • New or worsening psychosis, bipolar disorder, or mental health issues
  • Withdrawal symptoms if you suddenly stop using this medication – severe tiredness, sleep problems, mental/mood changes such as depression
  • Severe allergic reactions e.g. hives, shortness of breath

Your doctor will assess the benefits of using Adderall and Vyvanse against your risk of side effects. You are encouraged to report negative side effects or adverse reactions of Vyvanse to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Adderall and Vyvanse drug interactions

Adderall and Vyvanse can interact with other medications, including prescription drugs. In some instances, this can change how it and other medications work. It can even increase the likelihood and severity of some side effects. Medications that are known or thought to interact with Adderall and Vyvanse include:

  • Monoamine oxidase inhibitors, MAOIs, (methylene blue, phenelzine, or selegiline)
  • Tricyclic antidepressants (desipramine or protriptyline)
  • Medications that affect your serotonin system (SSRI or SNRI antidepressants, triptans, fentanyl, or St. John’s Wort)

Read the full prescribing information for Adderall and Vyvanse and always speak with your healthcare provider for medical advice about your medicine so they can monitor and evaluate your condition. Always inform your healthcare provider of all your medical conditions, and any medications you are taking, including over-the-counter meds and supplements.

Vyvanse and Adderall are two of the most commonly prescribed ADHD meds. While they both work to relieve symptoms, it may take trial and error to find what works best for you.

Entresto side effects and how to avoid them

Entresto is a brand-name prescription drug manufactured by Novartis Pharmaceuticals to treat heart failure. It is a single product containing two medications: sacubitril and valsartan. Sacubitril belongs to a group of drugs called neprilysin inhibitors used to control blood volume and lower blood pressure. Valsartan belongs to a class of drugs called angiotensin II receptor antagonists, used to relax blood vessels. Entresto can cause adverse reactions like any other drug. Learn more about the side effects of Entresto and how to avoid them.

What is Entresto?

Entresto is a prescription medication. It’s prescribed to:

  • Reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and heart failure with reduced ejection fraction (HFrEF)
  • Treat heart failure in children one year and older

Heart failure, also called congestive heart failure or cardiac failure results in high rates of morbidity and mortality. It occurs when your heart still beats but can’t pump enough blood around your body. This can reduce how much oxygen your organs receive, which can make it harder for them to function and can cause damage. Treatments for heart failure depend on the severity of your condition.

Entresto comes as an oral tablet. It helps to lower your blood pressure, making it easier to pump blood around your body. The medication is usually prescribed instead of other angiotensin medications, like angiotensin-converting enzyme (ACE) inhibitors or other angiotensin II receptor blockers (ARBs).

Entresto active ingredients

Entresto has two active ingredients that work in combination, sacubitril/valsartan. Sacubitril stops an enzyme called neprilysin from breaking down peptides that lower blood pressure. Valsartan reduces blood vessel tightening and the build-up of sodium and fluid. Both drugs make it easier for your heart to pump blood around your body.

Entresto dosage

Entresto is available in three tablet strengths:

  • 24/26 mg (sacubitril 24 mg and valsartan 26 mg)
  • 49/51 mg (sacubitril 49 mg and valsartan 51 mg)
  • 97/103 mg (sacubitril 97 mg and valsartan 103 mg)

Entresto is also available in an oral suspension. It can be substituted at the recommended tablet dosage in patients unable to swallow tablets. The starting dose of Entresto is normally 49 mg of sacubitril and 51 mg tablet of valsartan twice daily. The low dose is used in patient groups who are not currently taking an ACE inhibitor or an angiotensin II receptor blocker, patients with severe renal impairment, and patients with moderate hepatic impairment.

How effective is Entresto?

The FDA approval of Entresto was gained from the results of the PARADIGM-HF clinical trial involving 8442 heart failure patients. The aim of the study was to determine whether treatment with Entresto was superior to enalapril. Entresto showed superior efficacy in reducing heart failure hospitalizations, and cardiovascular death, and improving quality of life with comparable safety and tolerability vs enalapril ACE inhibitor.

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Entresto common side effects

Common possible side effects include:

  • Dizziness or feeling lightheaded
  • Cough
  • Headaches
  • Tiredness and weakness
  • Fainting
  • Diarrhea
  • Feeling sick (nausea)
  • Stomach pain (gastritis)

Entresto can cause more serious side effects, including:

  • Causing harm or death to your unborn baby
  • Swelling of your face, lips, tongue, and throat (angioedema) that may cause trouble breathing and death. People who are black and take Entresto may have a higher risk of having angioedema than people who are not black and take Entresto.
  • Severe allergic reactions to the medication that causes trouble breathing and death
  • Kidney problems, including reduced kidney function and kidney failure
  • Low blood pressure (hypotension), particularly if you also take diuretic medications
  • High potassium levels in your blood (hyperkalemia)

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Entresto drug interactions

Entresto can interact with other medications, including:

  • Any angiotensin medications, like angiotensin-converting enzyme (ACE) inhibitors such as lisinopril, captopril, benazepril, ramipril, quinapril, or angiotensin receptor blockers (ARBs) such as candesartan, or losartan
  • Any other medications taken to treat heart failure
  • Any other medications taken to treat other heart conditions
  • Any medications for high blood pressure
  • Any medications or supplements that can increase the level of potassium in your blood, like potassium supplements, salt substitutes containing potassium, potassium-sparing diuretics, or heparin
  • Any medications taken to treat diabetes, particularly ones that contain aliskiren
  • Any pain killers, particularly nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
  • Any diuretic medications (water pills)
  • Any antibiotics
  • Sildenafil (Viagra), used to treat erectile dysfunction or lung hypertension
  • Lithium, taken to treat some psychiatric disorders

Entresto warnings & precautions

Entresto can cause harm or death to your unborn baby. Don’t take Entresto if you’re pregnant. Talk to your doctor if you plan to become pregnant or do become pregnant while taking Entresto. This drug acts on the renin-angiotensin-aldosterone system therefore should be abruptly discontinued once pregnancy is confirmed. Entresto should not be given to children under one year of age.

Entresto can cause side effects, like dizziness, that can affect your ability to drive, use machinery, or perform other dangerous tasks. Avoid doing so until you’re confident Entresto doesn’t affect your ability to perform these activities.

Don’t take Entresto if you:

  • Are pregnant or are planning to become pregnant
  • Are allergic to the active ingredients sacubitril or valsartan
  • Are allergic to any of the other ingredients in Entresto
  • Have ever had an allergic reaction to an angiotensin-converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB) medication
  • Are currently taking an angiotensin-converting enzyme (ACE) inhibitor medication
  • Take a diabetes medicine that contains aliskiren

Talk to your doctor before taking Entresto if you:

  • Have any kidney problems or kidney disease
  • Have any liver problems or liver disease
  • Have a history of hereditary angioedema
  • Are breastfeeding or are planning to breastfeed. It is not known if sacubitril/valsartan is present in human breast milk.

How to avoid Entresto side effects

While completely avoiding Entresto side effects may not be possible, there are some things you can do to reduce their severity:

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional. It is typically taken twice a day, at the same time each day. Entresto can be taken with or without food. Sticking to the same timings and taking your medication consistently will make a big difference in how well Entresto works for you.

If you miss a dose of this medicine, skip the missed dose and take the next dose as scheduled. Using reminders or setting alarms on your phone may be helpful if missing doses is a problem. Refer to the medication guide for more drug information.

2. Store Entresto correctly

Entresto should be stored at room temperature in a dry place in its original container. Knowing how to properly store your medication is important to make sure it remains as effective as possible. Taking expired or improperly stored medication could result in the medication not working properly and may even cause unwanted side effects.

3. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Entresto will work for you. Give them a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Entresto that may increase possible side effects.

4. Keep hydrated

The active ingredient valsartan in Entresto can cause problems with elevated potassium levels and low blood pressure. Due to this, it’s important to stay hydrated and keep body fluids normal. Work with your healthcare professional to maintain hydration. Watch for signs of elevated potassium such as heart palpitations, weakness, and chest pain.

5. Stay active

The more you move, the better. Exercise has been shown to help improve heart health and staying active can be an easy way for people of all ages or backgrounds to improve their well-being. It’s also worth checking in with your doctor before starting any new physical activity plan because some activities may not work well with certain pre-existing medical conditions.

6. Pay attention to your body

Paying attention to how your body feels when taking Entresto is important, paying particular attention to low blood pressure as it is the most common side effect of Entresto. Seek medical attention for any sign of low blood pressure such as lightheadedness, dizziness, or fainting.

It is important to take notice of new heart failure symptoms or changes to current ones. Some symptoms that go unnoticed at times are shortness of breath, swelling, coughing, confusion or memory loss and rapid weight gain.

Talk to your doctor straight away if you start to experience any side effects of Entresto when taking it. Always seek medical advice if you are concerned about your medication.

Trintellix side effects and how to avoid them

Trintellix is a brand-name drug manufactured by Takeda pharmaceuticals. It is a U.S. Food and Drug Administration (FDA) approved prescription medication used to treat depression symptoms in a type of depression known as Major Depressive Disorder (MDD). Trintellix works in a unique way that doesn’t fit neatly into other antidepressant classes but has effects similar to selective serotonin reuptake inhibitors (SSRI). Trintellix is only used to treat major depressive disorder. It is not used for the treatment of anxiety, attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), or bipolar disorder.

Trintellix can cause adverse effects like any other drug. Learn more about Trintellix side effects that often lead to discontinuation of treatment and how to avoid them.

What is Trintellix?

Trintellix is an antidepressant prescribed to adults to treat Major depressive disorder (MDD). If you have MDD, your doctor may prescribe Trintellix to you, in addition to recommending other treatments. Trintellix works by increasing levels of a natural substance that regulates your brain activity called serotonin. This can reduce the severity of depressive episodes and help keep them at bay. You take Trintellix as an oral tablet that you swallow.

Trintellix active ingredients

The active ingredient in Trintellix is called vortioxetine. It’s a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). When you swallow a Trintellix tablet, it releases vortioxetine into your bloodstream. Vortioxetine is then carried in your blood to your brain, where it slows down how quickly your brain cells reabsorb a substance called serotonin.

Serotonin is a neurotransmitter that helps regulate your brain function, particularly areas of your brain involved in mood, learning, and memory. Your brain cells reabsorb excess serotonin, but vortioxetine slows down how quickly this happens, causing serotonin levels to rise. This can rebalance your serotonin levels. Research has shown this can help to reduce the symptoms of depression.

The body uses serotonin in many different ways: to regulate mood, control bowel movements, control nausea, and regulate sleeping and waking, and is also involved in blood clotting, bone health, and mental health. This neurotransmitter plays an important role in the body.

Trintellix dosage

Trintellix is available in three different strength immediate-release, film-coated tablets:

  • 5 mg
  • 10 mg
  • 20 mg

Your doctor will advise you on your dosing regime. Each individual will be different and the dose will change from person to person. Some patients may begin with the 5 mg dose, others may take the higher dose. Always follow your doctor’s instructions and seek medical advice if you are unsure about dosing. The medication guide for Trintellix will be provided by your pharmacist before you start taking Trintellix.

Never stop your medication abruptly without consulting your doctor as withdrawal symptoms are possible. In clinical trials, some patients experienced discontinuation symptoms such as headache, muscle tension, mood swings, sudden outbursts of anger, dizziness, and a runny nose. This may occur in the first week of sudden discontinuation of Trintellix 15 mg daily or 20 mg daily.

Side effects of Trintellix

The most common side effects are:

Sometimes, Trintellix can cause more serious side effects. These include:

  • Severe allergic reactions to the medication
  • An increased risk of suicidal thoughts and suicide, particularly in young adults
  • Serotonin syndrome – a potentially life-threatening condition caused by high levels of serotonin
  • An increased risk of bruising and bleeding, especially if taken with medications that can reduce blood clotting, like blood thinners, aspirin, or NSAIDs like ibuprofen
  • An increased risk of developing eye problems, including eye pain, swelling, and changes in vision
  • An increased risk of hypomania (manic episodes)
  • Hyponatremia – low sodium levels in your blood that can cause serious health problems and death

Suicidal thoughts and worsening mental health

Trintellix carries a boxed warning due to the risk for suicidal thoughts and actions. In studies, Trintellix was shown to increase suicidal thoughts and actions in some people 24 years of age and younger. Trintellix is not approved for use in pediatric patients.

A boxed warning is the strongest warning that the FDA requires. These warnings alert doctors and patients about drug effects that may be dangerous.

Serotonin syndrome

Serotonin syndrome occurs when serotonin levels in the body are dangerously high. This can happen when Trintellix is taken alone or with other antidepressants such as sertraline, citalopram, paroxetine, fluoxetine and escitalopram, attention deficit hyperactivity disorder drugs, St. John’s wort, and others.

Symptoms of serotonin syndrome can include:

  • High blood pressure
  • Confusion
  • Increased heartbeat
  • Agitation
  • Muscle rigidity
  • Diarrhea

Weight gain

Trintellix did not significantly impact weight in short-term studies and during a 6-month phase of a long-term study of patients who responded to Trintellix when compared to patients taking a sugar pill. Some reports of weight gain have been received since product approval.

Sexual dysfunction

Like other serotonergic antidepressants, Trintellix may cause sexual side effects during treatment. In 6 to 8-week clinical studies the overall incidence in sexual dysfunction was as follows: in male patients the overall incidence was 3%, 4%, 4%, 5% in Trintellix 5mg/day, 10 mg/day, 15 mg/day, 20 mg/day, respectively, compared to 2% in placebo. In female patients, the overall incidence was <1%, 1%, <1%, 2% in Trintellix 5 mg/day, 10 mg/day, 15 mg/day, 20 mg/day, respectively, compared to <1% in placebo. These results were from voluntary reports of sexual side effects of antidepressants which are known to be underreported in part because patients may be reluctant to discuss them.

When patients were proactively assessed using a self-rated questionnaire called the Arizona Sexual Experiences Scale (ASEX) different results were observed. This was designed to identify Treatment-Emergent Sexual Dysfunction used in seven Trintellix clinical trials to determine how many people actually experienced sexual side effects. The ASEX scale included five questions to obtain information on sex drive, ease of arousal, ability to achieve an erection (men) or lubrication (women), ease of reaching orgasm, and orgasm satisfaction.

The results showed that sexual dysfunction occurred in 34% of females and 16% to 29% of males and 22% who took Trintellix during the clinical studies. They were more likely to happen when higher doses of the drug were taken.

Male sexual dysfunction symptoms include:

  • Ejaculation delay or failure
  • Decreased libido
  • Erectile dysfunction symptoms may be seen

Female sexual dysfunction symptoms:

  • Decreased libido
  • Delayed orgasm
  • Absence of orgasm

Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment. Other alternatives are available.

Serious bleeding

When Trintellix is used with other medications that increase the risk of bleeding such as nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, or warfarin there is a serious bleeding risk. Nose bleeds, bleeding in the stomach or bleeding in the brain have the potential to occur.

Symptoms of serious bleeding can include:

  • Uncontrollable bleeding
  • Urine turning red, pink, or brown
  • Tarry stools red or black in color
  • Coughing up blood
  • Vomit that looks like coffee grounds

Low sodium levels

Certain people and people older than 65 years of age, or those taking a diuretic medication, are more likely to have this side effect. Trintellix can cause low sodium levels.

Symptoms of low sodium can include:

  • Trouble concentrating
  • Headache
  • Confusion
  • Weakness

Trintellix drug interactions

Trintellix can interact with other medications, including:

  • Monoamine oxidase inhibitors (MAOI) medications such as linezolid, methylene blue, isocarboxazid, phenelzine, and tranylcypromine
  • Strong CYP2D6 inhibitors such as Cardioquin (quinidine), Prozac (fluoxetine), Paxil (paroxetine), and bupropion (Wellbutrin). Your doctor may decrease your dose of Trintellix.
  • Strong CYP inducers, such as Dilantin (phenytoin) Rifadin or Rimactane (rifampin), Tegretol, or Epitol (carbamazepine). Your doctor may increase your dose of Trintellix.
  • Tricyclic antidepressants such as lithium
  • Any selective serotonin reuptake inhibitor (SSRI) antidepressant such as sertraline (Zoloft), citalopram (Celexa), paroxetine, fluoxetine, and escitalopram (Lexapro)
  • Any serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant such as duloxetine and venlafaxine (Effexor)
  • Any other medications taken to treat major depressive disorder
  • Any other medications that can affect your serotonin levels
  • Buspirone, taken most often to treat anxiety disorders
  • Any antipsychotic medications
  • Opioid painkillers, like tramadol or fentanyl
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or naproxen
  • Triptans used for migraines
  • Aspirin
  • Warfarin, an anticoagulant (blood thinner) taken to reduce the risk of blood clots
  • A herbal supplement called St. John’s Wort

Trintellix warnings & precautions

Antidepressants can increase the risk of suicidal thoughts and suicide in children and young adults, particularly during the first few months of treatment. Trintellix is not for use in children, but young adults taking it should be monitored for signs of sudden changes in behavior, mood, thoughts, or feelings. Seek urgent medical attention if you, or someone you care for, feels they are at risk of suicide.

Don’t take Trintellix if you:

  • Are allergic to the active ingredient vortioxetine, or any of the other ingredients in Trintellix
  • Are currently taking a monoamine oxidase inhibitor (MAOI) antidepressant or have taken one in the last 14 days
  • Are under 18 years of age

Talk to your doctor before taking Trintellix if you:

  • Have bipolar disorder or mania
  • Have any liver problems
  • Have a personal or family history of angle-closure glaucoma
  • Have or have ever had seizures/convulsions
  • Have or have ever had any problems with bleeding
  • Have low salt (sodium) levels in your blood
  • Regularly drink alcohol
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Pregnancy and Trintellix

Your doctor may weigh the risks and benefits when prescribing Trintellix during pregnancy. Using Trintellix during the third trimester of pregnancy can increase the risk for persistent high blood pressure in the pulmonary artery and withdrawal in the newborn.

If you are pregnant or plan on becoming pregnant, it is best to speak with your healthcare provider before starting a medication.

Breastfeeding

Talk to your healthcare provider if you are breastfeeding or planning to breastfeed. It is unknown if this drug passes into breast milk.

Can you mix Trintellix and alcohol?

Trintellix’s prescribing information does not list alcohol as a contraindication or warning but is strongly discouraged by healthcare professionals. Trintellix can worsen the effects of alcohol, while alcohol can worsen the side effects of Trintellix. When you have depression, you have an increased risk of developing a substance use disorder. Therefore mixing antidepressants with alcohol can lead to alcohol abuse, increasing the potential to become alcohol dependent. If you drink and develop an addiction to alcohol, it will become more difficult for you to control your symptoms of depression and get your alcohol consumption under control. You may need more frequent and long-term treatment if you have both an alcohol use disorder and depression.

The combination of alcohol and antidepressants can be very challenging if someone is drinking, binge drinking, heavy drinking, or has an alcohol use disorder prior to taking antidepressants. Furthermore, if someone decides to stop taking drugs for depression and starts drinking alcohol for symptom management instead, they can worsen their symptoms of depression, in some cases leading to suicidal thoughts.

How to avoid Trintellix side effects

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional once daily at the same time each day with water. Taking your medication consistently will make a big difference in how well Trintellix works for you.

Your healthcare provider may adjust your dose of Trintellix or your other medications to find the best dosage for your specific needs.

2. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Trintellix will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements especially St. John’s wort and tryptophan, and health conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Trintellix and help manage any possible side effects.

3. Reduce alcohol intake

Although alcohol doesn’t interact directly with Trintellix, mixing Trintellix and alcohol together is strongly discouraged by healthcare professionals. Both work on slowing down the central nervous system causing drowsiness, sedation, and impairment. When taken together however they can create health problems for you, impact your mental health further, cause challenges in your home life with loved ones, and other serious concerns.

If you are planning to drink alcohol and you have Major depressive disorder, aim to always stay within the recommended guidelines. This is the safest way to drink alcohol.

4. Pay attention to your body

Paying attention to how your body feels when taking Trintellix is important. If you or loved ones around you see new or sudden changes in your mood, behavior, thoughts or feelings, or symptoms that are new or worsening, or if you develop suicidal thoughts or actions get emergency help right away.

Talk to your doctor straight away if you start to experience any side effects of Trintellix when taking it, or if you feel the medication is not working for you. There are many other treatment options available.

5. Try to stay healthy

Managing depression with drugs is one way to keep symptoms under control. Another way to keep yourself mentally healthy is to:

  • Explore your interests
  • Taking regular exercise
  • Eating healthy
  • Getting enough sleep
  • Keeping hydrated

5. Store Trintellix correctly

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not store it in the bathroom.

Knowing how to store your medication is important to make sure it remains as effective as possible. Using expired or improperly stored medication could result in the medication not working properly and even causing unwanted side effects.

NuvaRing side effects and how to avoid them

Choosing a birth control method can be a difficult decision as there are so many options. Hormonal contraceptives are commonly used and one option is NuvaRing, a flexible birth control vaginal ring used to prevent pregnancy. Oral birth control pills are absorbed through the digestive tract however with NuvaRing the hormones are released directly into the bloodstream. Like other hormonal birth control methods, NuvaRing also increases the risk of serious blood clots, especially in women who have other risk factors, such as smoking. Let’s take a look at the adverse reactions associated with the NuvaRing and how to avoid them.

What is NuvaRing?

NuvaRing is a prescription birth control vaginal ring used to prevent pregnancy. It is a soft and flexible ring that is slightly larger than a 50-cent piece. You use it by inserting it into your vagina (following the patient information instructions that come with your NuvaRing ). Once inside you, NuvaRing releases two substances into your body that are man-made versions of the natural hormones estrogen and progestin, that stop you from getting pregnant.

How to use NuvaRing

NuvaRing is used in a 4-week cycle. You wear a NuvaRing for three weeks at a time, then you take it out for one week before you insert a new ring. During the one week that you do not wear a NuvaRing, you usually have your period. If used properly, NuvaRing is just as effective as the contraceptive pill, but you do not need to take it every day. The NuvaRing is simple to insert, similar to a tampon.

NuvaRing active ingredients

NuvaRing contains two active ingredients called ethinylestradiol and etonogestrel. Ethinylestradiol is a synthetic (man-made) version of the hormone estrogen that your body naturally produces. Etonogestrel is a synthetic version of the hormone progesterone produced naturally by your body.

Estrogen and progesterone are hormones that play a role in the female reproductive cycle. The ethinylestradiol and etonogestrel in NuvaRing have the same effects on your body as these natural hormones. They stop your ovaries from releasing an egg each month (ovulation). They can also change the lining of your womb (uterus), stopping a fertilized egg from attaching to it and developing. Finally, they can change the mucus created by your cervix (the opening of your womb), which can prevent sperm from entering your womb.

Dosing of NuvaRing

When placed in the vagina, each ring releases on average 0.120 mg/day of etonogestrel and 0.015 mg/day of ethinyl estradiol over a three-week period of use.

NuvaRing has an outer diameter of 54 mm and a cross-sectional diameter of 4 mm. It is made of ethylene-vinyl acetate copolymers and magnesium stearate and contains 11.7 mg etonogestrel and 2.7 mg ethinyl estradiol. NuvaRing is not made with natural rubber latex.

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Side effects of NuvaRing

The most common side effects caused by NuvaRing include:

  • Vaginal irritation
  • Vaginal discharge
  • Cervix irritation discomfort, and pain
  • Breakthrough bleeding
  • Problems with the ring slipping out, moving, and causing discomfort
  • Migraine headaches
  • Severe headaches
  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Breast tenderness or pain
  • Painful menstrual periods
  • Abdominal pain
  • Acne
  • Weight gain
  • A fall in sexual desire (libido)
  • Mood changes, including depression and thoughts of self-harm

In rare instances, NuvaRing can cause more serious side effects, including:

  • Risk of developing blood clots, including serious blood clots that can cause deep vein thrombosis, pulmonary embolism, venous thromboembolism, vision loss, strokes, and heart attacks
  • Severe allergic reactions to the medication cause skin rashes, hives, fever, and swelling in the face, mouth, and throat that can make it difficult to breathe
  • Toxic shock syndrome – a potentially fatal condition caused by bacteria infecting your NuvaRing
  • Liver problems, including liver tumors
  • Gallbladder problems
  • High blood pressure
  • Problems caused by accidentally inserting your NuvaRing into your bladder
  • Angioedema – inflammation of the lower layers of your skin and the tissue under your skin

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Boxed warning for NuvaRing

NuvaRing has an FDA (U.S. Food and Drug Administration) boxed warning for the risk of serious cardiovascular events from combination hormonal contraceptives in women over 35 years old who smoke.

Do not use NuvaRing if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious heart and blood vessel problems from combination hormonal contraceptives, including heart attack, blood clots, or stroke, which can be life-threatening.

Toxic Shock Syndrome (TSS)

A rare but potential side effect of NuvaRing is toxic shock syndrome a fatal condition. The condition is caused when bacteria get into the body and releases harmful toxins. It is associated commonly with tampon use in young women but it can affect women of any age.

When the NuvaRing is inserted into the vagina there is potential for bacteria to grow on the ring. This is why it is essential that it is removed after 3 weeks. The symptoms of TSS can start suddenly and get worse quickly, they include:

  • Sudden high temperature
  • A sunburn-like rash
  • Muscle aches
  • Vomiting
  • Low blood pressure

Blood clots

This side effect relates to the black box warning associated with NuvaRing. Another serious side effect that can occur with NuvaRing is blood clots. Symptoms of a blood clot in the legs, lungs, eyes, heart, or brain are persistent leg pain, sudden shortness of breath, sudden partial or complete blindness, severe chest pain or pressure, sudden severe headaches, weakness or numbness in a limb, trouble speaking, or yellowing of the skin or eyeballs.

NuvaRing drug interactions

NuvaRing can interact with other medications, particularly:

  • Any other contraceptives
  • Any antiviral medications taken to treat an HIV infection, including ritonavir, atazanavir, indinavir, saquinavir, or nelfinavir
  • Any antiviral medications taken to treat a hepatitis C infection, including boceprevir or telaprevir
  • Any other antiviral medications taken to treat another viral infection
  • Any antibiotics taken to treat a bacterial infection, including rifampicin, clarithromycin, or telithromycin
  • Any antifungal medications taken to treat a fungal infection, including ketoconazole and itraconazole
  • Any medications taken to lower cholesterol levels, including atorvastatin or rosuvastatin
  • Any anticonvulsant medications taken to reduce the chances of you having seizures, like carbamazepine, phenobarbital, or phenytoin
  • Any thyroid replacement therapies
  • A medicine called bosentan, taken to treat high blood pressure in the vessels of the lung
  • A medicine called aprepitant, taken to treat chemotherapy-induced nausea and vomiting
  • A medicine called acetaminophen, taken to relieve pain
  • Ascorbic acid (vitamin C)
  • A herbal supplement called St John’s wort

NuvaRing warnings & precautions

Do not drink grapefruit juice, eat grapefruit or eat anything that contains grapefruit when using NuvaRing, as grapefruit contains an ingredient that can affect how NuvaRing works.

NuvaRing is not suitable for everyone. Don’t use a NuvaRing if you:

  • Are allergic to the active ingredients ethinylestradiol and etonogestrel
  • Are allergic to any of the other ingredients in NuvaRing (you can find these listed in the leaflet which comes with the medication)
  • Have any unusual vaginal bleeding
  • Have ever had a heart attack
  • Have ever had a stroke
  • Have or have had blood clots in your body
  • Have an inherited condition that increases your risk of blood clots
  • Have a heart valve problem or heart rhythm problem that can cause blood clots in your heart
  • Smoke any tobacco products and are over 35 years old (this puts you at an increased risk of blood clots)
  • Have or have ever had breast cancer, cancer of the womb (uterus), or another cancer that is sensitive to female hormones
  • Have high blood pressure that’s not controlled by medicine
  • Have diabetes with kidney, eye, nerve, or blood vessel damage
  • Have liver disease
  • Get severe migraines with visual auras or get mild to severe migraines and are over 35 years old
  • Think you may be pregnant
  • Are not a woman that can get pregnant
  • Are under 18 years of age

Talk to your doctor before taking NuvaRing if you:

  • Are taking any of the medications that could interact with NuvaRing (see the section above)
  • Smoke any tobacco products
  • Have recently been pregnant, have given birth, have had a miscarriage, or an abortion
  • Are breastfeeding or are planning to breastfeed
  • Have a family history of breast cancer
  • Have or have had breast nodules, fibrocystic disease, an abnormal breast x-ray, or an abnormal mammogram
  • Have ever had toxic shock syndrome
  • Have any liver problems, including jaundice during pregnancy
  • Have ever had heart disease
  • Have ever had liver disease
  • Have ever had kidney disease
  • Have ever had gallbladder disease
  • Have ever had high blood pressure
  • Have ever had a seizure
  • Have ever had a migraine
  • Have diabetes
  • Have a history of missed or irregular menstrual periods
  • Have ever been diagnosed with depression
  • Are due to have any form of surgery, including a dental procedure
  • Are due to have any form of laboratory test, such as a blood test, as NuvaRing can affect the results of some tests

How to avoid NuvaRing side effects

1. Read the patient information for NuvaRing use

When used as directed by your healthcare professional NuvaRing has been shown to be very effective. Your chance of getting pregnant depends on how well you follow the directions for using NuvaRing. The better you follow the directions, the less chance you have of getting pregnant.

Follow the instructions on how to insert a NuvaRing thoroughly and seek help from your doctor if you are unsure. The patient leaflet will show you a step-by-step guide on the correct way to insert NuvaRing. It is possible to accidentally insert the NuvaRing into your bladder. If you have pain during or after insertion and you cannot find NuvaRing in your vagina, call your health care provider right away.

2. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well NuvaRing will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, medical conditions you may have, and if you smoke. Talking with your doctor will allow them to pick up any drug interactions with NuvaRing and help manage any possible side effects.

3. Pay attention to your body

Paying attention to how your body feels when taking NuvaRing is important. As mentioned earlier in the blog, blood clots and TSS are a risk with NuvaRing. If you experience any of the symptoms associated with these serious side effects seek medical help urgently.

Due to NuvaRing entering your bloodstream directly it can bring on a more powerful reaction. It is important that you learn which symptoms are dangerous so you can treat them quickly with medical advice and attention.

Talk to your doctor straight away if you start to experience any side effects of NuvaRing when taking it, or if you feel the medication is not working for you.

5. Store NuvaRing correctly

Store NuvaRing at room temperature for up to 4 months after you receive it. Throw NuvaRing away if the expiration date on the label has passed. Do not store NuvaRing above 86°F (30°C) and avoid direct sunlight. To dispose of NuvaRing place the used NuvaRing in the re-closable foil pouch and throw it away in your household trash. Do not flush your used NuvaRing down the toilet.

Dupixent side effects and how to avoid them

Dupixent is a biologic drug that is produced from living organisms. Just like conventional drugs, all biologic drugs must be approved by the Food and Drug Administration (FDA) for safety and effectiveness.

Dupixent reduces the amount of inflammation your immune system can cause by blocking two proteins called interleukin-4 (IL-4) and interleukin-13 (IL-13) in the inflammation process. This helps to reduce the severity of your symptoms. It can reduce eczema outbreaks, reduce asthma symptoms and help you breathe more easily, and help you to recover from chronic rhinosinusitis with nasal polyposis.

Dupixent can cause adverse reactions as can all medications. It’s important to talk to your healthcare professional for medical advice about possible side effects that trouble you or are persistent. Learn more about Dupixent’s adverse effects and how to avoid them.

What is Dupixent?

Dupixent is the brand name of an injectable medicine used to reduce inflammation. It is prescribed to:

  1. Adults and children 6 years and older to treat moderate-to-severe atopic dermatitis (eczema) when topical treatments can not be used or are not effective enough. Dupixent can be used with or without topical corticosteroids
  2. Adults and children 12 years and older to treat eosinophilic asthma or asthma that requires oral corticosteroids
  3. Adults to treat a nasal and sinus condition called chronic rhinosinusitis with nasal polyposis, alongside other medications for the condition, such as antibiotics

What is a biologic drug?

Biologics or biological medicines originate from living cells, such as humans, animals, or microorganisms using biotechnology, whereas chemically derived drugs are created in laboratories. Chemically derived or traditional drugs are described as small molecule drugs. Biologic drugs on the other hand are much larger in size, containing more complex molecules, making them challenging and costly to make. The growth of the cells in biologic medications can take several weeks and requires constant monitoring. The protein that makes up the drug is extracted and purified until the final biologic drug is obtained.

Biological products include a wide range of products including:

  • Vaccines
  • Blood components
  • Gene therapy
  • Tissues
  • Proteins, like monoclonal antibodies and cell signaling proteins

The manufacturing process of biological drugs makes it impossible to guarantee that each batch of a biologic drug will be identical to the last, which means every dose of a biologic medicine has slight variations.

Dupixent active ingredients

The active ingredient in Dupixent is called dupilumab. It is a type of drug called a monoclonal antibody that has been designed to attach to a specific type of white blood cell in your body called a B cell.

Your immune system produces B cells to help trigger inflammation. But when you take Dupixent, the dupilumab it contains attaches to B cells at areas on their surface called receptors. This blocks the receptors and stops them from receiving the chemical trigger to begin the inflammatory process. This reduces how much inflammation your immune system can cause, easing the symptoms of inflammatory disease.

How should I use Dupixent?

Dupixent is a prescription drug that is taken by injecting it under the skin (subcutaneous injection) in the thigh, stomach area, or upper arm, using a prefilled syringe or pre-filled injection pen. Dupixent should be used exactly as prescribed by your doctor. Your healthcare professional will work out the dose of Dupixent and your dosing schedule.

Dupixent is available as

  • A single dose pre-filled syringe (100 mg, 200 mg, or 300 mg) with a needle shield
  • A single-dose pre-filled pen (200 mg or 300 mg) for ages 12+ years

Before Dupixent is started your doctor will arrange proper training on preparing and injecting. Your healthcare provider will decide if you or your caregiver can give the Dupixent injections.

It is advised that Dupixent is given by or under adult supervision in children and adolescents 12 years of age and older. A caregiver should administer Dupixent pre-filled syringes to children 6-11 years of age.

What do I do if I miss a dose?

This depends on your dosing schedule but as a guide:

  • If you take this drug every 2 weeks – take the missed dose as soon as you think about it. If it has been 7 days or more since your missed dose, skip the missed dose and go back to your normal time
  • If you take this drug every month – take the missed dose as soon as you think about it. If it has been 7 days or more since your missed dose, take the missed dose and start a new schedule based on when you took the dose

Your doctor will advise you on exactly what should be done if a dose is missed.

Common side effects of Dupixent

As with all medications, Dupixent can cause side effects. Only some people get side effects, however, and these side effects can vary by person.

The most common possible side effects caused by Dupixent include:

  • Injection site reactions, such as swelling and pain
  • Inflammation in your eyes and eyelids (blepharitis)
  • Conjunctivitis (pink eye)
  • Dry eye
  • Cold sores around your lips and in your mouth
  • A sore throat
  • Trouble sleeping (insomnia)
  • Joint pain
  • Toothache
  • Inflammation in your stomach (gastritis), that can cause indigestion and nausea

In rare instances, Dupixent can cause more serious side effects. These include:

  • Severe allergic reactions to the medication, symptoms include skin rashes, hives, fever, swelling in the face, mouth, and throat, and breathing problems
  • Hypersensitivity reactions such as serum sickness (an immune system reaction that causes fever, rash, and joint pain or swelling)
  • New or worsening eye problems, including eye pain, keratitis (inflammation of the cornea), and changes in vision
  • Inflammation of your blood vessels (vasculitis) – this is rare, but most likely to happen in patients with asthma who also take a corticosteroid medication

Your doctor will assess the benefits of taking Dupixent against your risk of side effects.

Side effects related to a specific condition

In clinical trials the side effects for specific conditions treated by Dupixent differ:

Atopic dermatitis

The most common adverse effects in adult patients treated for Atopic dermatitis were injection site reactions, conjunctivitis, blepharitis, oral herpes, keratitis, eye pruritus, and other herpes simplex virus infection, and dry eye.

Asthma

The most common adverse effects were injection site reactions, oropharyngeal pain, and eosinophilia.

Chronic rhinosinusitis with nasal polyposis

The most common adverse effects were injection site reactions, eosinophilia, insomnia, toothache, gastritis, arthralgia, and conjunctivitis.

Dupixent drug interactions

Dupixent can interact with other medications. This can change how Dupixent and the other medications work and can make some side effects more likely. Tell your prescribing doctor about all drugs you are taking, particularly:

  • Any other medications you take for your inflammatory condition
  • Any oral, topical, or inhaled corticosteroid medicines

Dupixent warnings & precautions

Dupixent is a maintenance medication used to help lessen and control your asthma symptoms. It should not be used to treat sudden and severe onsets of asthma (such as an asthma attack). Use your rescue inhaler to treat sudden and severe asthma symptoms, or whatever rescue medication your doctor has prescribed to you.

Dupixent should not be given to children under 6 years of age to treat eczema, children under 12 years of age to treat asthma, or children under 18 years of age to treat chronic rhinosinusitis with nasal polyposis.

This medication is not suitable for everyone. Do not take Dupixent if you are allergic to the active ingredient dupilumab, or any of the other ingredients in Dupixent. Talk to your doctor before taking Dupixent if you:

  • Are taking any of the medications that could interact with Dupixent
  • Have or have ever had any eye problems
  • Have recently had or are due to have a live vaccination
  • Have a parasitic infection (helminth)
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Use of Dupixent in pregnancy and breastfeeding

It is not known if Dupixent is safe to take during pregnancy or while breastfeeding. If you’re pregnant, breastfeeding, or planning either, talk with your doctor. They can recommend the safest way to treat your condition during this time.

Dupixent food interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Dupixent, there are no specific foods that you must exclude from your diet when receiving this medication.

Where can I get more information?

Your pharmacist or healthcare provider can provide more drug information about Dupixent.

How to avoid Dupixent side effects

1. Stick to the recommended dosage

Take your prescribed dose of Dupixent that has been recommended by your healthcare professional. Taking your medication consistently will make a big difference in how well Dupixent works for you.

Your healthcare provider may adjust your dose of Dupixent or your other medications to find the best dosage for your specific needs.

2. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Dupixent will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Dupixent and help manage any possible side effects.

3. Rotate injection sites

The importance of rotating insulin injection sites is to maintain effective drug absorption. Small fatty lumps or hard lumps could develop in areas that are continuously used as injection sites. This can interfere with drug absorption and also cause discomfort. Rotate between injecting sites of the thigh, stomach area, or upper arm. Always clean your skin with an alcohol wipe. Please do not touch the injection site again or blow on it before the injection. Let your skin dry before injection and do not rub your skin after the injection.

4. Use Dupixent at room temperature

To ensure comfortable injection of Dupixent remove the Dupixent pen injector or prefilled syringe from the refrigerator about 45 minutes before injection. This will allow the medicine to warm to room temperature. Injecting cold medicine is painful.

5. A caregiver must inject Dupixent for children

Although Dupixent can be self-injected, caregivers should always give the injection to children and adolescents to maximize both safety and effectiveness.

6. No live vaccines

Live vaccines should not be given to Dupixent patients right before or during treatment, these include:

  • Chickenpox (varicella) vaccines
  • FluMist (the flu vaccine given as a nasal spray)
  • MMR vaccines (measles, mumps, and rubella)
  • Japanese encephalitis vaccine
  • Rotavirus vaccines
  • Smallpox vaccine
  • Yellow fever vaccine

7. Cold compress on your eye

Dupixent can commonly cause inflammation in your eyes and eyelids (blepharitis), conjunctivitis (pink eye), and dry eye. It is usually not serious but more irritating. You may find relief with just a cool compress or over-the-counter eye relief drops. A more severe eye infection may require prescription medication.

If you notice vision changes or develop eye pain, contact your doctor. They can suggest the next steps to help manage your eye problems.

8. Stay active

To avoid joint pain while taking Dupixent some of the following things may help;

  • Daily stretching
  • Make sure you are physically active to help keep your joints strong
  • Look at over-the-counter (OTC) options for pain relief

9. Tell your doctor if you suffer from cold sores

Cold sores around the lip and mouth can occur when taking Dupixent. If you’re concerned about this particularly if you’re prone to getting them, talk with your doctor. They can recommend the best treatment plan to have in place. This way, you’ll know what to do at the first sign of a cold sore.

10. Pay attention to your body

Paying attention to how your body feels when taking Dupixent is important. For example, listen to your body and rest your joints when needed if they’re painful. Talk to your doctor straight away if you start to experience any side effects of Dupixent when taking it, or if you feel the medication is not working for you.

11. Store Dupixent correctly

Refrigerate Dupixent at 36°F to 46°F in the original carton to protect from light.

If needed Dupixent may be kept at room temperature up to 77°F (25°C) for a maximum of 14 days. Do not store above 77°F (25°C). After removal from the refrigerator, Dupixent must be used within 14 days or discarded. Keep Dupixent away from heat or direct sunlight. Do not freeze. Do not shake.

Knowing how to store your medication is important to make sure it remains as effective as possible. Using expired or improperly stored medication could result in the medication not working properly and even causing unwanted side effects.

Januvia alternatives: which other diabetes medications can I take?

Januvia is a brand name diabetes drug manufactured by Merck Pharmaceuticals. It is one of many diabetes medicines used to control blood glucose levels in people with type 2 diabetes mellitus.

The number of medications available to treat type 2 diabetes in particular, is long and confusing at first. No single diabetes treatment is best for everyone and what works for one person may not work for another. Always seek medical advice when considering changing medication.

Let us take a look at the alternative diabetes medications available to Januvia, simplify how they work, and what common side effects they may have. This knowledge will allow you to discuss the different treatment options with your doctor.

What is Januvia?

Januvia is a prescription medicine approved by the U.S Food and Drug Administration to:

  • Treat type 2 diabetes, by helping to lower blood sugar levels when used in combination with exercise and changes to your diet

In type 2 diabetes you do produce insulin, but the body can not use it effectively. There is usually a combination of a part failure of insulin production and a reduced response to the hormone. This is known as insulin resistance. Research does not give us a clear idea why some people develop this and others don’t, but lifestyle factors, e.g. lack of exercise and excess body weight can contribute to type 2 diabetes. Januvia is not recommended to be used to treat type 1 diabetes.

Januvia active ingredients

The active ingredient in Januvia is called sitagliptin. It works by increasing the amount of insulin you produce after you’ve eaten.

When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP. These hormones make your pancreas secrete insulin. As you continue to digest your food, the digestive hormones are broken down by an enzyme called dipeptidyl peptidase-4 (DPP-4) to allow your levels of insulin to fall again.

Sitagliptin stops the DPP-4 enzyme from breaking down the digestive hormones. This keeps the hormones active for longer, making you produce more insulin, and lowering your blood sugar to normal levels.

Side effects of Januvia

The most common side effects of Januvia include:

  • Headaches
  • Stuffy or runny nose
  • Sore throat
  • An increase in upper respiratory tract infections, like colds, sinus infections, and the flu
  • Constipation

Often these side effects disappear after a few weeks of use. Occasionally, Januvia can cause more serious side effects. These include:

  • Severe joint pain
  • Heart failure
  • Inflammation of the pancreas (pancreatitis) can be fatal in severe cases
  • Serious allergic reactions to the medication can cause anaphylaxis – a potentially life-threatening condition where your immune system overreacts, causing hives, swelling in your face, mouth, and throat that causes shortness of breath and trouble breathing
  • Kidney problems that can reduce kidney function or require dialysis
  • Dangerously low blood sugar levels (hypoglycemia)

Your doctor will assess your risk of side effects versus the benefits of taking Januvia.

If you take Januvia you could experience side effects, including the most serious, but everyone reacts differently to medication. If you have any concerns about side effects, talk to your physician or a pharmacist. You may report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

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Januvia alternatives

Biguanides

This class of drug is one of the earliest medications for diabetes. Biguanides such as metformin are used regularly as a first-line treatment for type 2 diabetes and are the most common medication used for diabetics. It is unsuitable for anyone with liver, kidney, or heart problems.

How do Biguanides work?

  • Slows down the absorption of glucose from your intestines
  • Reduces how much sugar your liver makes
  • Helps to reduce your insulin resistance

Advantages of Biguanides

  • No weight gain side effects
  • Very effective

The most common side effects caused by Biguanides include:

  • Decrease in vitamin B12 absorption
  • Bloating
  • Diarrhea
  • Nausea
  • Weight loss

Common Biguanides brands:

Meglitinides

How do Metiglinides work?

  • Stimulates the release of insulin from your pancreas

Advantages of Metiglinides:

  • Works quickly
  • Allows you to be flexible with your dose

The most common side effects caused by Meglitinides include:

  • Stomach pain
  • Indigestion
  • Feeling sick
  • Diarrhea
  • Weight gain
  • Low blood sugar (hypoglycemia)

Popular Meglitinide brands include:

  • Prandin (repaglinide)
  • Prandimet (repaglinide-metformin)
  • Starlix (nateglinide)

Sulfonylureas

How do Sulfonylureas work?

  • Stimulates the cells of your pancreas to make and release more insulin

Advantages of Sulfonylureas:

  • Effective in lowering your blood sugar level
  • You can take different formulations

The most common side effects caused by Sulfonylureas:

  • Diarrhea
  • Feeling sick
  • Skin rashes
  • Itching
  • Weight gain
  • Low blood sugar (hypoglycemia)

As with insulin, Sulfonylureas can be classed as short, medium, or long-acting depending on how fast they work.

  • Short-acting – tolbutamide (Rastinon)
  • Medium-acting – glimepiride (Amaryl)
  • Long-acting – chloropropamide (Diabinese)

Glinides

How do Glinides work?

  • Stimulates your pancreas to produce more insulin

Advantages of Glinides:

  • Fast-acting

Possible side effects:

  • Low blood sugar
  • Weight gain
  • Nausea
  • Diarrhea
  • Constipation

Common Glinides:

  • Prandin – repaglinide
  • Starlix – nateglinide

Thiazolidinediones

How do Thiazolidinediones work?

  • Causes changes in your muscle and fat cells where insulin resistance occurs

Advantages of Thiazolidinediones:

  • Does not cause low blood sugar
  • May protect beta cells in your pancreas

The most common side effects caused by Thiazolidinediones include:

  • Headaches
  • An increase in upper respiratory tract infections (like colds and throat infections)
  • Fluid build-up that causes swelling in your hands, feet, and ankles
  • Weight gain

Popular Thiazolidinediones include:

  • Actos – pioglitazone
  • Avandia – rosiglitazone

Alpha-glucosidase inhibitors

How do Alpha-glucosidase inhibitors work?

  • Interrupts the breakdown of carbohydrates into sugar in your gut, so it stops your body from absorbing glucose

Advantages of Alpha-glucosidase inhibitors:

  • Especially useful if you have type 2 diabetes where your blood sugar tends to be most out of control after eating

The most common side effects caused by Alpha-glucosidase inhibitors include:

  • Bloating
  • Gas
  • Diarrhea
  • Abdominal cramps
  • Stomach pain

Common brands include:

  • Glyset – miglitol
  • Precose – acarbose

Dopamine agonists

How do Dopamine agonists work?

  • It’s not known exactly how this drug works to treat type 2 diabetes. It may affect rhythms in your body and prevent insulin resistance

Advantages of Dopamine agonists:

  • Does not cause low blood sugar or weight gain

The most common side effects caused by Dopamine agonists include:

  • Heartburn
  • Feeling sick
  • Vomiting
  • Loss of appetite
  • Drowsiness
  • Dizziness

Common brands include:

Dipeptidyl peptidase-4 (DPP-4) inhibitors (Gliptins)

Januvia is in this drug class and there are alternatives within the same class you may want to consider.

How do Dipeptidyl peptidase-4 inhibitors work?

  • Blocks the production of an enzyme called Dipeptidyl peptidase-4 allowing your body to release more insulin

Advantages of Dipeptidyl peptidase-4 inhibitors:

  • Does not cause low blood sugar or weight gain
  • Possible beneficial effects on cholesterol levels

The most common side effects caused by DPP-4 inhibitors include:

  • Upper respiratory infection
  • Nausea
  • Headaches
  • Mild indigestion

Common brands:

  • Onglyza – saxagliptin
  • Galvus – vildagliptin

Glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) / Incretin memetics

How does it work?

  • An injected medicine that helps prevent your blood sugar from rising after eating by slowing the rate of digestion and the release of insulin

Advantages:

  • May suppress hunger
  • Modest weight loss

Side effects:

  • Nausea
  • Headache
  • Diarrhea
  • Low blood sugar

Common brands:

Amylin mimetics

How do Amylin mimetics work?

  • Helps control your glucose levels
  • Slows the movement of food through your stomach
  • Used with insulin injections

Advantages of Amylin mimetics:

  • May suppress hunger
  • It may help with some weight loss

Possible side effects:

  • Hypoglycemia (low blood sugar levels)
  • Nausea
  • Vomiting

Common brands:

  • Symlin – pramlintide

Sodium-glucose transporter (SGLT) 2 inhibitors

How do SGLT2 inhibitors work?

  • Sodium-glucose transporter SGLT2 inhibitors work by preventing your kidneys from holding on to glucose. Instead, your body gets rid of the glucose through your urine

Advantages of SGLT2 inhibitors:

  • These drugs may possibly reduce your risk of cardiovascular disease, heart failure, or chronic kidney disease. The ADA recommends SGLT2 inhibitors as a possible treatment option

The most common side effects caused by SGLT2 inhibitors include:

  • Nausea
  • Constipation
  • Dehydration
  • Risk of genital yeast infections
  • Risk of urinary tract infections
  • Low blood sugar (hypoglycemia)

Popular SGLT2 inhibitor brands include:

Bile acid sequestrants

How do Bile sequestrants work?

  • It is thought to lower glucose levels in your bloodstream by attaching itself to bile acids in your intestines
  • Researchers are still working to understand how exactly it works

Advantages of Bile sequestrants:

  • Safer if you have liver problems

Side effects:

  • Gas
  • Constipation
  • Indigestion

Common brands:

  • Welchol – colesevelam

Combination Oral Pills

Over time as a type 2 diabetic, your medication will change as your diabetes progresses. You may require multiple medications to keep your blood sugar level stable and within the safe range. Combination oral pills combine the effects of two medications in one drug.

Examples of combination medications for type 2 diabetes:

  • Glucovance – metformin and glyburide
  • Metaglip – metformin and glipizide
  • Avandaryl – rosiglitazone and glimepiride
  • ACTOplus Met – pioglitazone and metformin
  • Avandamet – rosiglitazone and metformin
  • Duetact – pioglitazone and glimepiride

Other diabetes medications

Diabetes is much more than just blood glucose levels e.g. type 2 diabetics have a higher risk of heart attacks and strokes, therefore medications to control blood pressure and cholesterol are very useful.

Here are some of the most widely used medications:

  • ACE inhibitors – act on your kidneys to treat high blood pressure
  • AIIRA’s – reduces high blood pressure
  • Aspirin – reduces the stickiness of your blood, making you less prone to heart attacks and stroke
  • Statins – they lower your LDL cholesterol (considered the bad cholesterol) and raise your HDL (considered good cholesterol) helping to protect you against heart disease

As a diabetes patient, it is essential to discuss your medical history with your healthcare provider to avoid complications and to help them understand how well your medication will work for you. Give a complete list of all the prescription medications, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions and help manage any possible side effects.

Entresto alternatives: which other heart medications can I take?

Entresto is a combination of two drugs a neprilysin inhibitor and an angiotensin II receptor blocker (ARB) used for the treatment of heart failure. Entresto is the only drug in the angiotensin receptor-neprilysin inhibitor (ARNI) class so there are no alternatives in the same drug class but there are many other alternatives to look at. You may be considering alternative medications due to cost as Entresto is currently only available as a brand-name drug. Even with insurance or Medicare, it is an expensive treatment option. Read on to find out more.

What is Entresto?

Entresto is a prescription medication manufactured by Novartis Pharmaceuticals to treat heart failure. It’s prescribed to:

  • Reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and heart failure with reduced ejection fraction (HFrEF)
  • Treat heart failure in children one year and older

Heart failure, also called congestive heart failure or cardiac failure results in high rates of morbidity and mortality. It occurs when your heart still beats but can’t pump enough blood around your body. This can reduce how much oxygen your organs receive, which can make it harder for them to function and can cause damage. Treatments for heart failure depend on the severity of your condition.

Entresto comes as an oral tablet. It helps to lower your blood pressure, making it easier to pump blood around your body. The medication is usually prescribed instead of other angiotensin medications, like angiotensin-converting enzyme (ACE) inhibitors or another angiotensin II receptor blockers (ARBs).

Entresto active ingredients

Entresto has two active ingredients that work in combination, called sacubitril/valsartan. Sacubitril stops an enzyme called neprilysin from breaking down peptides that lower blood pressure. Valsartan reduces blood vessel tightening and the buildup of sodium and fluid. Both drugs make it easier for your heart to pump blood around your body.

Entresto dosage

Entresto is available in three tablet strengths:

  • 24/26 mg (sacubitril 24 mg and valsartan 26 mg)
  • 49/51 mg (sacubitril 49 mg and valsartan 51 mg)
  • 97/103 mg (sacubitril 97 mg and valsartan 103 mg)

Entresto is also available in an oral suspension. It can be substituted at the recommended tablet dosage in patients unable to swallow tablets. The starting dose is normally 49 mg of sacubitril and 51 mg of valsartan twice daily. The low dose is used in patient groups who are not currently taking an ACE inhibitor or an angiotensin II receptor blocker, patients with severe renal impairment, and patients with moderate hepatic impairment.

How effective is Entresto?

The FDA approval of Entresto was gained from the results of the PARADIGM-HF clinical trial involving 8442 heart failure patients. The aim of the study was to determine whether treatment with Entresto was superior to enalapril.

Entresto side effects

Common possible side effects include:

  • Dizziness
  • Cough
  • Headaches
  • Tiredness and weakness
  • Fainting
  • Diarrhea
  • Feeling sick (nausea)
  • Stomach pain (gastritis)

Entresto can cause more serious side effects, including:

  • Causing harm or death to your unborn baby
  • Severe allergic reactions to the medication that cause problems with breathing and death
  • Kidney problems, including reduced kidney function and kidney failure
  • Low blood pressure (hypotension), particularly if you also take diuretic medications
  • High potassium levels in your blood (hyperkalemia)

Entresto drug interactions

Entresto can interact with other medications, including:

  • Any angiotensin medications, like angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs)
  • Any other medications taken to treat heart failure
  • Any other medications taken to treat other heart conditions
  • Any medications that lower your blood pressure
  • Any medications or supplements that can increase the amount of potassium in your blood, like potassium supplements, salt substitutes containing potassium, potassium-sparing medicines, or heparin
  • Any medications taken to treat diabetes, particularly ones that contain aliskiren
  • Any pain killers, particularly nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
  • Any diuretic medications
  • Any antibiotics
  • Sildenafil (Viagra), used to treat erectile dysfunction or lung hypertension
  • Lithium, taken to treat some psychiatric disorders

Entresto warnings & precautions

Entresto can cause harm or death to your unborn baby. Don’t take Entresto if you’re pregnant. Talk to your doctor if you plan to become pregnant or do become pregnant while taking Entresto. This drug acts on the renin-angiotensin-aldosterone system therefore should be abruptly discontinued once pregnancy is confirmed.

Entresto should not be given to children under one year of age.

Entresto can cause side effects, like dizziness, that can affect your ability to drive, use machinery, or perform other dangerous tasks. Avoid doing so until you’re confident Entresto doesn’t affect your ability to perform these activities.

Don’t take Entresto if you:

  • Are pregnant or are planning to become pregnant
  • Are allergic to the active ingredients sacubitril or valsartan
  • Are allergic to any of the other ingredients in Entresto
  • Have ever had an allergic reaction to an angiotensin-converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB) medication
  • Are currently taking an angiotensin-converting enzyme (ACE) inhibitor medication
  • Take a diabetes medicine that contains aliskiren

Talk to your doctor before taking Entresto if you:

  • Have any kidney problems
  • Have any liver problems
  • Have a history of hereditary angioedema
  • Are breastfeeding or are planning to breastfeed

Entresto alternatives

Patients with heart failure have many types of drugs available to help with symptoms and improve reduction in cardiovascular death. Multiple drugs to treat the condition are often taken by patients.

Always seek medical advice from your healthcare provider when looking to change medication. They can provide you with up-to-date drug information and guidelines from the American College of Cardiology and the American Heart Association to work out the best treatment for you. Below are some alternatives to Entresto.

Enalapril

Vasotec is the brand name of enalapril an angiotensin-converting enzyme inhibitor (ACE inhibitor) indicated for the:

  • Treatment of hypertension (high blood pressure) in adults and children older than one month, to help lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions
  • Treatment of symptomatic congestive heart failure
  • Treatment of asymptomatic left ventricular dysfunction, to decrease the rate of development of overt heart failure and reduce hospitalization for heart failure

See the full prescribing information for the complete boxed warning. When pregnancy is detected, discontinue treatment as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.

BiDil

BiDil is a heart failure medicine prescribed to self-identified African American patients. It contains the active ingredients isosorbide dinitrate and hydralazine. It is the only heart failure medicine specifically indicated for self-identified African American patients. You take BiDil as an oral tablet, usually three times a day, but your doctor will tell you how much BiDil to take and how often. BiDil can be used alone or alongside other heart failure medications.

The medication helps treat your heart failure by opening up your blood vessels and reducing your blood pressure, making it easier for your heart to pump blood around your body. This can reduce your chances of needing to be hospitalized and can help you live with your condition more easily and for longer.

Carvedilol

Coreg is the brand name product of the active ingredient carvedilol. Carvedilol is a beta-blocker used to treat high blood pressure and help prevent heart disease, heart attacks, and strokes. It is given with other medicines, generally diuretics to treat heart failure. Carvedilol works by slowing down your heart rate, therefore, making it easier for blood to pump around the body. It is available in four different doses, 3.125mg, 6.25mg, 12.5mg and 25mg. The dose depends on the condition you are treating. For heart failure patients 3.125mg twice a day for 2 weeks. The dose will then slowly increase on advice from your doctor.

Spironolactone

Spironolactone is an aldosterone antagonist that works on the kidneys to increase the elimination of water and sodium, helping to lower blood pressure. This process results in an increase in potassium in the blood which can be dangerous if not monitored closely.

Aldactone is the brand name of spironolactone and it is indicated for the treatment of NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and reduce the need for hospitalization for heart failure. This drug is usually administered in conjunction with other heart failure therapies.

Valsartan

Diovan is the brand name of valsartan an angiotensin receptor blocker (ARB) that relaxes and widens your blood vessels lowering your blood pressure. The usual dose for heart failure patients is 40mg-160mg twice daily but the dosage will be determined by your doctor. Valsartan is one of the drugs present in Entresto.

What to do if you want to switch to an alternative

Your doctor will advise you on the safest way to stop taking Entresto and then how to start a new drug. Suddenly stopping Entresto may have a worsening effect therefore always follow your doctor’s guidelines. If your doctor decides an ACE inhibitor is suitable for you then a 36-hour elimination time is needed between the last dose of Entresto and the first dose of the ACE inhibitor. This is required to minimize dangerous levels of angioedema.

Discussing your medical history with your prescribing healthcare provider is important to help them understand which alternative will work for you. Some drugs have dangerous drug interactions and must be avoided. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will also allow them to pick up any drug interactions that may increase possible side effects.

Januvia side effects and how to avoid them

Januvia is a brand name diabetes drug manufactured by Merck Pharmaceuticals. It is one of many diabetes medicines used to control blood glucose levels in people with type 2 diabetes mellitus. It is often prescribed with other diabetes medications such as metformin.

Januvia can cause adverse reactions as can all medications. The more common side effects of Januvia tend to be upper respiratory tract infections but some patients may develop severe and disabling joint pain. It’s important to talk to your healthcare professional for medical advice about possible side effects that trouble you or are persistent. Learn more about Januvia’s side effects and how to avoid them.

What is Januvia?

Januvia is a prescription medicine approved by the U.S Food and Drug Administration to

  • Treat type 2 diabetes, by helping to lower blood sugar levels when used in combination with exercise and changes to your diet

If you have type 2 diabetes, your body may not produce enough insulin or may become resistant to the effects of insulin. This means less sugar is removed from your blood and your blood sugar levels stay too high. High blood sugar levels can cause a range of problems over time, including nerve damage, heart disease, strokes, and kidney failure.

Januvia treats type 2 diabetes by helping to lower your blood sugar levels. It encourages your pancreas to produce insulin for longer after you’ve eaten, helping your body absorb more sugar out of your blood. Januvia can not treat diabetic ketoacidosis or type 1 diabetes.

Januvia active ingredients

The active ingredient in Januvia is called sitagliptin. It works by increasing the amount of insulin you produce after you’ve eaten.

When you digest food, your stomach and gut produce digestive hormones called GLP-1 and GIP. These hormones make your pancreas secrete insulin. As you continue to digest your food, the digestive hormones are broken down by an enzyme called dipeptidyl peptidase-4 (DPP-4) to allow your levels of insulin to fall again.

Sitagliptin stops the DPP-4 enzyme from breaking down the digestive hormones. This keeps the hormones active for longer, making you produce more insulin, and lowering your blood sugar to normal levels.

Side effects of Januvia

The most common side effects of Januvia include:

  • Headaches
  • A stuffy or runny nose
  • A sore throat
  • An increase in upper respiratory tract infections, like colds, sinus infections, and the flu
  • Constipation

Often these side effects disappear after a few weeks of use. Occasionally, Januvia can cause more serious side effects. These include:

  • Severe joint pain
  • Heart failure
  • Inflammation of the pancreas (pancreatitis) can be fatal in severe cases
  • Serious allergic reactions to the medication can cause anaphylaxis – a potentially life-threatening condition where your immune system overreacts, causing hives, swelling in your face, mouth, and throat that causes shortness of breath and trouble breathing
  • Kidney problems that can reduce kidney function or require dialysis
  • A serious skin rash called bullous pemphigoid that can cause large, fluid-filled blisters
  • Skin reactions called Stevens-Johnson Syndrome
  • Dangerously low blood sugar levels (hypoglycemia)

Your doctor will assess your risk of side effects versus the benefits of taking Januvia.

If you take Januvia you could experience side effects, including the most serious, but everyone reacts differently to medication. If you have any concerns about side effects, talk to your physician or a pharmacist. You may report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

Severe joint pain

Some patients who take DPP-4 inhibitor drugs like Januvia can suffer from severe joint pain starting from day 1 or it may occur many years into treatment. The FDA issued a Drug Safety Communication in 2015 adding warnings for severe joint pain with this class of drug and required drug companies to add this to drug labels. Merck the manufacturers of Januvia advises people who experience joint pain to talk to their doctors about discontinuing the drug.

When the drug was stopped, relief from symptoms was seen by patients but restarted when treatment commenced with the same DPP-4 inhibitor drug or a different DPP-4 inhibitor drug.

Heart failure

Merck added a warning about the risk of heart failure to Januvia in 2017. Januvia has not been linked to heart failure directly but other drugs in the same drug class have.

A U.S. Food and Drug Administration (FDA) safety review found that type 2 diabetes medicines containing saxagliptin and alogliptin may increase the risk of heart failure, particularly in patients who already have heart or kidney disease. The FDA looked at two large clinical studies that showed more patients who took the drugs were admitted to the hospital for heart failure compared to patients who took a placebo.

Patients taking these drugs are advised to contact their doctor immediately if they develop signs of heart failure, symptoms include:

  • Shortness of breath
  • Weakness
  • Trouble breathing
  • Weight gain with swelling in the ankles, feet, legs, or stomach

Inflammation of the pancreas

Merck advises patients and healthcare professionals that pancreatitis is a serious side effect of Januvia and can lead to death. Pancreatitis is inflammation of the pancreas, the organ that produces insulin and glucagon. Tell your doctor immediately if you develop severe and persistent pain in your stomach.

Januvia has been associated with sometimes fatal pancreatitis. It’s uncertain if Januvia is a risk in people who have a history of pancreatitis. However, it is advised that all patients taking Januvia are monitored for pancreatitis when they start taking Januvia.

Januvia drug interactions

Certain medications can interact with each other, affecting how they work and making some side effects more likely. Medications that are known or thought to interact with Januvia include:

  • Other medications that can lower blood sugar levels such as insulin or a sulfonylurea medicine
  • Digoxin which is used to treat a range of heart conditions

Januvia warnings & precautions

Don’t take Januvia if you:

  • Are allergic to the active ingredient sitagliptin
  • Are allergic to any of the other ingredients in Januvia (listed in the leaflet which comes with the medication)
  • Have type 1 diabetes
  • Are under 18 years of age

Talk to your doctor before taking Januvia if you:

  • Have a history of pancreatitis (inflammation of the pancreas)
  • Have gallstones, alcohol dependence, or have very high levels of triglycerides. These medical conditions can increase your risk of getting pancreatitis
  • Have a heart condition
  • Have kidney disease
  • Are breastfeeding or plan to breastfeed, or if you express milk in another way, such as with a breast pump
  • Are over 65 years of age

Read the full prescribing information for Januvia and always speak with your healthcare provider for medical advice about your medicine so they can monitor and evaluate your condition. Always inform your healthcare provider of all medical conditions, and medications taken including over-the-counter meds and supplements.

Can Januvia affect pregnancy?

There’s no research on how Januvia can affect your unborn baby. There is a registry that monitors pregnant women taking Januvia, but there isn’t sufficient data yet to judge the drug’s safety during pregnancy.

In animal studies (rats and rabbits), no adverse effects on pregnancy were found, even with high doses of Januvia, but animal studies don’t always predict how a drug will affect human biology. If you’re taking Januvia and fall pregnant, or are trying for a baby, talk to your doctor.

For breastfeeding, there’s no data on whether or not Januvia can pass into breast milk in humans. This was found to be the case in animal studies, so there is a possibility Januvia could pass into your breast milk. Talk to your doctor about taking Januvia if you are breastfeeding or plan to breastfeed, or if you express milk in another way, such as with a breast pump.

How to take Januvia?

Always take your Januvia exactly as directed by the doctor who prescribed it to you. Januvia comes as a tablet that you swallow. You typically take Januvia once a day, at the same time each day. You have to swallow Januvia tablets whole, don’t break or crush them up. You can take Januvia tablets with or without food or water.

What is the best time of day to take Januvia?

There is no recommended best time of the day to take Januvia. Just make sure you take Januvia at the same time each day, at a time convenient to you.

What if I miss a Januvia dose?

Januvia is taken as a pill that’s swallowed, usually once a day in the following doses: 25 mg, 50 mg, and 100 mg. If you miss a Januvia dose, take the dose as soon as you remember. If you don’t remember until it’s time for your next dose, skip the missed dose and don’t take a double dose, as you may take too much Januvia and risk an overdose.

Januvia overdose

If you take too much Januvia, you increase your risk of side effects, including serious side effects.

Symptoms of a Januvia overdose include:

  • Chest pain
  • A rapid heartbeat
  • Feeling shaky and nervous
  • Excessive sweating
  • Changes in your thinking and reasoning

If you’ve taken too much Januvia, you should seek emergency medical attention.

What should I avoid while taking Januvia?

There are no specific foods or drinks you need to avoid when taking Januvia, although you should make sure you stick to your diabetes diet while taking the medication. You should also be careful about drinking alcohol with Januvia.

Birth control pills can make Januvia less effective. Talk to your doctor about the best forms of contraception for you when taking Januvia.

There are also certain medications you should avoid when taking Januvia, as they can interact with it.

How to avoid Januvia side effects

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional once daily at the same time each day with water. Taking your medication consistently will make a big difference in how well Januvia works for you.

Your healthcare provider may adjust your dose of Januvia or your other medications to find the best dosage for your specific needs.

2. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Januvia will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Januvia and help manage any possible side effects.

3. Reduce alcohol intake

Although alcohol doesn’t interact directly with Januvia, it can lower your blood sugar and make hypoglycemia (low blood sugar) more likely if you’re taking diabetes medications. Drinking alcohol can also increase your risk of pancreas damage. This is known as pancreatitis and can lead to permanent damage to the pancreas and its ability to manage the production, storage, and release of insulin.

Drink any alcohol in moderation when taking Januvia if your diabetes is well controlled and you have no problems with your pancreas. Avoid alcohol when taking Januvia if your diabetes is not well controlled and/or you have any problems with your pancreas.

If you are planning to drink alcohol and you have diabetes, aim to always stay within the recommended guidelines. This is the safest way to drink alcohol.

4. Pay attention to your body

Paying attention to how your body feels when taking Januvia is important, as uncontrolled blood sugar can be fatal. It is useful to keep a diary log of your blood glucose readings and how you are feeling.

Seek immediate medical attention if you feel your blood sugar levels are uncontrolled. People will have different symptoms of low blood sugar. Headache, drowsiness, weakness, confusion, irritability, hunger, fast heartbeat, and sweating are most common. It is important that you learn which symptoms you usually have so you can treat them quickly.

Talk to your doctor straight away if you start to experience any side effects of Januvia when taking it, or if you feel the medication is not working for you.

5. Store Jardiance correctly

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not store it in the bathroom.

Knowing how to store your medication is important to make sure it remains as effective as possible. Using expired or improperly stored medication could result in the medication not working properly and even causing unwanted side effects.

The Elder Fraud Report Revisited

Revisiting our report on the patterns & changes in fraud committed against elders

We previously brought you our elder fraud report where we delved into the data surrounding scams and fraudulent schemes targeting the over 60s across the US. With new data now available, we are able to dive back into the figures to find out how elder fraud has changed over the course of a year and whether elders are at more or less risk now than they were in previous years.

What is elder fraud?

There are a number of types of elder fraud and targeted scams that can con people out of their money, with millions of elderly US citizens falling victim to it each year.

With the ever-evolving world of technology being somewhat confusing and intimidating for many elderly citizens, some may be more susceptible to falling victim to scams that involve technology.

From extortion to romance scams, there are numerous ways in which fraudsters target the elderly, many of which we will explore in this report, as well as the losses and prevalence of these frauds.

The states where elder fraud is most prevalent

Some states seem to have to deal with elder fraud more often than others, with there being thousands of incidents in each state during 2021. So, with this in mind, which states had the highest rate of elder fraud?

Most Prevalent Elder Fraud States

  • California – 12,951 victims

Remaining in top place is California, with a rise of 3.33% since 2020. While 2020 saw 12,534 victims over the age of 60, 2021 saw 12,951 Californian elders fall victim to fraud and scams.

  • Florida – 9,645 victims

Again, following the 2020 ranking, Florida places second with 9,645 victims. Again, this is an increase from 2020 of 4.25%, with more Floridians falling victim to fraud in 2021 than the previous year.

  • Texas – 6,798 victims

Rounding out the top three is another repeat from the 2020 ranking, with another sizeable increase. Texas sees a rise in victims of 7.19%, going from 6,342 elder victims in 2020 to 6,798 in 2021.

The states where elder fraud is most costly

While the number of victims of fraud and scams can seem alarming, the financial losses experienced by these victims is even more shocking.

Most Costly Elder Fraud States

  • California – $427.26 million

Again, California retains its number one position with elderly Californians losing over $427 million in 2021. This is a huge sum, especially when we consider the amount of money lost in 2020 – $152.64 million. This equates to a massive increase of 179.91% and averages out to $32,991 per victim.

  • Florida – $224.20 million

Remaining in the second spot for another year, Floridian elders lost a whopping $224.20 million in 2021. This equates to $23,246 per victim and is a 164.86% increase since 2020’s figure of $84.65 million.

  • New York – $188.05 million

Replacing Texas in third place is New York, where elders lost $188.05 million in 2021. This is $30,219 per victim and a 128.81% increase since 2020.

The most common types of elder fraud

There are many ways in which elderly people are defrauded and scammed out of their hard-earned money, but which are the most common types?

Most Common Types of Elder Fraud

  • Tech Support – 13,900 victims

While in 2020, this type of scam placed third with 9,429 victims, in 2021, this was the most common type of elder fraud with 13,900 victims over the age of 60.

Tech support fraud involves fraudsters posing as technical support workers, often claiming that the victim has a computer virus or that their online banking has been compromised. These scams often end with the victim unwittingly transferring money to the fraudster or even handing over online banking details.

  • Non-Payment/Non-Delivery – 13,220 victims

Maintaining second place in the top three most common scams is non-payment/non-delivery which decreased in 2021 with 13,220 victims as opposed to the 14,534 victims in 2020.

This fraud type involves offering and advertising an item for sale with no intention of sending the item ordered when payment is made.

  • Identity Theft – 8,902 victims

Moving up from position four to position three, identity theft is the third most common elder fraud type with 8,902 victims in 2021, a considerable increase from 2020 when there were 7,581 victims.

This type of fraud involves a fraudster stealing and using personal information in order to commit fraud, other crimes or to takeover bank accounts.

The most costly types of elder fraud

Each different type of elder fraud can cost victims millions of dollars every year, but which type of fraud has cost over 60s the most in 2021?

Most Costly Types of Elder Fraud

  • Confidence Fraud/Romance – $432.08 million

Confidence fraud and romance scams retain the top spot in 2021, but they see a huge 53.69% increase in losses compared to the 2020 losses of $281.13 million.

Costing the average victim $56,422, these scams are costing elders more than ever in 2021, perhaps owing to fraudsters taking advantage of the massive levels of loneliness felt across the country during the pandemic lockdowns. As the world has started to open up again, this may be presenting scammers with more opportunities to persuade victims to part with their cash through romance scams.

  • BEC/EAC – $355.80 million

This type of fraud stays in the number two spot, though with a considerable increase in financial losses of 110.79%, with the 2020 losses being $168.79 million. In 2021, the $355.80 million losses equate to an average loss of $94,755 per victim.

Business email compromise/email account compromise, otherwise known as BEC/EAC targets businesses and individuals respectively, fraudulently accessing email accounts and using them to transfer funds from the victim.

  • Investment – $239.47 million

Lastly, investment fraud rises from the number four spot to sit in the top three after a huge increase in financial losses of 144.26% from $98.04 million to $239.47 million.

These schemes convince victims to invest in illegitimate investments, promising massive rewards based on false information.

Methodology:

All data is taken from a 2021 Elder Fraud Report produced by the Federal Bureau of Investigation and is an update of a previous report.

If you are unable to afford your medication, we may be able to assist. NiceRx provides access to FDA-approved brand-name medications, including Januvia, Janumet, Aubagio, Creon, and Trelegy Ellipta.

How much does Entresto cost with Medicare

In 2022, the manufacturer of Entresto (Novartis) states that around 80% of individuals with Medicare Part D prescription drug plans pay less than $50 per month in out-of-pocket costs for Entresto, and over 50% of people with Medicare Part D pay $10 or less for their Entresto prescription each month. That’s a significant saving compared to uninsured individuals who pay the full list price of $623.69 for Entresto, as stated on the manufacturer’s (Novartis) website.

The amount an individual pays for Entresto with prescription insurance coverage depends on various factors such as:

  • the type of Medicare coverage
  • the formulary tier (list of covered drugs in the plan)
  • whether the individual has reached their annual deductible amount
  • coinsurance or copayments

What is Entresto?

Entresto (sacubitril/valsartan) is an FDA-approved prescription medication used to treat heart failure. It’s a combination of two drugs: sacubitril and valsartan. Sacubitril is an inhibitor of neprilysin, while valsartan is an angiotensin receptor blocker (ARB). This combination works by widening blood vessels and reducing the amount of water and salt retained in the body. Entresto relaxes blood vessels and reduces blood pressure. It helps to reduce the risk of cardiovascular death and hospitalization in individuals with chronic heart failure.

The CDC estimates that there are around 6.2 million adults in the United States who have heart failure. If you have been diagnosed with heart failure, it’s important to talk to your doctor about whether Entresto may be right for you. As always, be sure to thoroughly discuss any potential side effects and other considerations before starting treatment.

Is there a generic version of Entresto?

There is currently no generic version of Entresto available on the market. Individuals who are prescribed this medication will need to purchase the brand-name drug, Entresto.

Does Medicare cover Entresto?

Novartis, the manufacturer, estimates that Entresto has preferred coverage for more than 99% of people with Medicare, on average.

However, note that Medicare Part A (hospital insurance) does not cover Entresto because it is not a hospital-administered medication. As well, Medicare Part B (medical insurance) does not cover Entresto because it is considered an outpatient medication.

Medicare Part D plans (prescription drug plans) and Medicare Advantage plans with prescription drug coverage (MAPDs) may cover Entresto. However, the coverage and costs will vary depending on your specific insurance plan. To learn more about whether Medicare covers Entresto, talk to your healthcare provider or contact Medicare directly for more information about your Medicare Part D coverage. They can help you determine what level of coverage is available for Entresto under your specific plan.

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Medicare Part D plans and Entresto coverage

Each Medicare prescription drug plan has its own rules about how much it will cover for each type of drug in its formulary (list of covered drugs). Some plans may place Entresto on a higher tier of their formulary (list of covered drugs), which means that patients will have to pay a higher coinsurance or copayment for the medication. Other plans may exempt Entresto from the annual deductible amount.

If an individual has a Medicare Part D prescription drug plan or a Medicare Advantage Prescription Drug (MAPD) plan, they will likely pay a monthly premium, an annual deductible, and coinsurance or copayments for their Entresto prescription medication. No Medicare drug plan may have a deductible of more than $480 in 2022 which means that you are responsible for the first $480 of out-of-pocket costs for your prescription drugs before your coverage commences. In the Donut Hole (also known as the Coverage Gap) stage, there is a temporary limit to what Medicare will cover for your prescription medication. As such, you may pay more for this medication until you have met your annual deductible amount.

Medicare Part D prescription drugs are the most common way of obtaining coverage from Medicare for prescription drugs such as Entresto. If an individual has Medicare Part D, also called prescription drug coverage, they may be able to get Entresto at a lower cost. Part D plans have a list of covered drugs (formulary drug list) and use tiered formularies. The cost of Entresto depends on which tier the drug is placed in the health insurance company’s formulary and may require prior authorization from your insurance company.

Entresto and Medicare Advantage

Medicare Advantage plans (Medicare Part C) are an alternative to the Original Medicare. If the Medicare Advantage plan includes prescription drug coverage, it may be possible to obtain Entresto at a lower cost. Advantage plans use tiered formularies and the cost of Entresto depends on which tier the drug is placed in the health insurance company’s formulary.

If you are interested in learning more about how much Entresto costs with Medicare, speak to your healthcare provider or contact Medicare directly for more information about their Part D coverage of this medication.

Can Medigap plans help me save money on Entresto?

No, it is not possible to use Medicare Supplement Insurance (Medigap) with prescription drugs. Medigap plans are supplemental insurance plans that may help cover some of the costs that Original Medicare does not cover, such as copayments, coinsurance, and deductibles.

How much does Entresto cost with Medicare?

The cost of Entresto will vary depending on a number of factors, including insurance coverage and the pharmacy you use.

In 2022, the drug manufacturer of Entresto (Novartis) states around 80% of individuals with Medicare Part D prescription drug plans pay less than $50 per month in out-of-pocket costs for Entresto, and over 50% of people with Medicare Part D pay $10 or less for their Entresto prescription each month, according to the manufacturer, Novartis.

Entresto assistance for Medicare patients

If you have Medicare and need help paying for your Entresto prescription medication, there are a few options that might be able to help you save money.

  • With the Entresto Co-Pay Card, you may be eligible to pay as little as $10 for a 30, 60, or 90 day supply of Entresto. You can bring your co-pay card along with your prescription to a participating pharmacy. The offer from the manufacturer is not valid under Medicare, Medicaid, or any other federal or state program. To see if you qualify for this program, visit the manufacturer’s website or speak with your doctor.
  • Novartis, the manufacturer of Entresto, offers a free trial offer which is available for all patients regardless of insurance coverage. To redeem this offer, patients are required to present this offer at a participating pharmacy along with a valid Entresto prescription from their healthcare provider. The voucher is valid for 30 days (up to a maximum of 60 tablets).
  • Enrollment in Patient Assistance Programs (PAPs) is also an option to help you pay for Entresto.
  • You may also be eligible for Extra Help. Extra Help is a program from the Social Security Administration that helps people with limited incomes and resources pay for their Medicare prescription drug costs. To see if you qualify for Extra Help, visit the Social Security Administration’s website or call 1-800-772-1213.
  • If you cannot afford your medication, your doctor may be able to provide you with samples of Entresto from the manufacturer.

Eliquis alternatives: which other blood thinners can I take?

No matter which blood-thinning medication you use, there will always be an increased risk of bleeding problems, but one treatment may suit you better than another. You may be looking for an alternative prescription drug to Eliquis due to adverse effects, drug interactions, or poor blood clot control. Whatever the reason may be, it’s good to know about other treatment options. Continue reading to learn about Eliquis alternatives.

What is Eliquis?

Eliquis is an FDA-approved brand-name drug. It is an anticoagulant, a type of drug that stops blood clotting (from a liquid to a thick gel).

Eliquis is indicated for the following conditions:

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib, or irregular heartbeat known as an arrhythmia)
  • Prevent deep vein thrombosis (DVT) in the legs and pulmonary embolism (PE) in the lungs of patients who have had a hip replacement or knee replacement surgery
  • Treatment of deep vein thrombosis (DVT) in the legs
  • Treatment of pulmonary embolism (PE) in the lungs
  • Reduce the risk of recurrent DVT and PE

Eliquis (apixaban) is not recommended for patients with artificial heart valves.

How does Eliquis work?

The active ingredient in Eliquis is an anticoagulant called apixaban. As blood clots, it goes through a process of chemical reactions that turn it from a liquid into a thick gel. An enzyme called factor Xa is an important part of this process. The active ingredient apixaban attaches itself to factor Xa to stop it from working, reducing the likelihood of blood clots forming.

What doses of Eliquis are available?

Eliquis is available in the following doses: 2.5 mg tablets and 5 mg tablets.

The recommended dose of Eliquis is 5 mg orally twice daily. Your recommended dosage will depend on the condition you are being treated for, your age, weight, and your renal function. Eliquis starts working within 3 to 4 hours after you take your first dose.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition. There is a higher risk of blood clots or a stroke if Eliquis (apixaban) is stopped too soon. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose.

Side effects of Eliquis

The most common side effects are related to bleeding, such as

  • Nosebleeds
  • Bleeding gums
  • Heavier menstrual bleeding
  • Unexpected vaginal bleeding

Serious side effects that can sometimes occur when taking Eliquis can include:

  • Serious allergic reactions to the medication. Symptoms include hives, chest pain, and trouble breathing
  • Bleeding in your brain and spinal column
  • Bleeding in your lungs
  • Bleeding into a muscle
  • Unusual bleeding
  • Vomiting blood that looks like coffee grounds
  • Tarry stools

Eliquis drug interactions

Eliquis and other medications can interact with each other. These interactions can change how the drugs work and can make side effects more likely. Don’t take Eliquis if you’re taking any other medications to prevent blood clotting, like warfarin. Talk to your physician if you’re taking any of the following:

  • An antifungal medicine
  • Antiviral medicines for HIV/AIDS
  • Anti-inflammatory medicines
  • Pain medications
  • Medicines for high blood pressure or heart problems
  • Antidepressants
  • Medicines to prevent epilepsy or seizures
  • Medicines to treat tuberculosis
  • St John’s Wort

Eliquis alternatives

Coumadin or Jantoven (warfarin)

Vitamin K antagonists such as warfarin (Coumadin, Jantoven) block the amount of vitamin K available for the blood coagulation pathway to produce clotting factors II, VII, IX, and X. This reduces the blood’s ability to clot or blood clots growing in size in your blood and blood vessels.

It is important to keep the amount of vitamin K in your diet low so that your doctor can calculate the right dose of daily warfarin for you. You’ll get regular blood tests so your doctor can track the effects of your dose and your diet. Your doctor will likely use the international normalized ratio test, or INR, to check on how well your blood can clot. The newer blood thinners such as Eliquis don’t need monitoring with blood clots.

Coumadin is prescribed for people:

  • With certain types of irregular heartbeat
  • With prosthetic (replacement or mechanical) heart valves
  • Who have suffered a life-threatening heart attack
  • To treat or prevent venous thrombosis
  • To treat or prevent pulmonary embolism

Xarelto (rivaroxaban)

Xarelto contains the active ingredient rivaroxaban and is approved to treat atrial fibrillation. Unlike Eliquis, it can be used to reduce the risk of cardiovascular problems, heart attack, and stroke in people with coronary artery disease. Xarelto may be preferred over Eliquis due to its once-daily dosing.

RELATED: Eliquis vs Xarelto

Pradaxa (dabigatran)

Pradaxa is a direct oral anticoagulant like Eliquis to treat atrial fibrillation. The active ingredient in Pradaxa is called dabigatran. It’s a blood thinner (anticoagulant) that stops your blood from clotting. Dabigatran works by blocking thrombin. When you swallow Pradaxa, molecules of dabigatran are absorbed in your blood, where they bind to thrombin. This stops thrombin from working and blocks a step of the clotting process.

The dose of Pradaxa does not need to be adjusted in people with liver problems unlike with Eliquis. Pradaxa can also be used in children aged 8 years and older.

RELATED: Pradaxa vs Eliquis

Savaysa (edoxaban)

Savaysa contains the active ingredient edoxaban and works as a factor Xa inhibitor just like Eliquis but only needs to be taken once daily instead of twice daily. Savaysa is not recommended in people with moderate to severe liver problems.

Heparin

Heparin injection is an anticoagulant medication that is used to decrease clotting of the blood and it also helps to prevent harmful clots from forming in the blood vessels. While Heparin will not dissolve blood clots that have already formed, this medication may prevent the blood clots from enlarging and causing problems that are more serious.

Low molecular weight heparins (LMWH)

Low molecular weight heparins are more predictable and last longer, which means your doctor doesn’t need to track its effects as closely as with other anticoagulants like warfarin. Low molecular weight heparin drugs include dalteparin (Fragmin) or enoxaparin (Lovenox). Doctors prescribe a fixed-dose based on your body weight. You inject this medication under your skin.

Is there a cheaper alternative to Eliquis?

Fortunately, there are cheaper alternatives to Eliquis available. Warfarin, known by the brand names Coumadin and Jantoven, is a comparable generic drug that can cost as little as $5 per month. Speak with your doctor to find out if Warfarin is medically appropriate for you. Unfortunately, Eliquis generic is not yet available in the United States.

Final word

Some medicines can cause drug interactions with blood-thinning drugs and cause serious problems. Tell your healthcare provider about all the medicines you take. This includes over-the-counter medicines, supplements like vitamin K, minerals, or herbal supplements. Medical advice from a cardiologist or another healthcare professional must be taken when changing from one drug to another.

How much is Trulicity without insurance

Trulicity can be a very expensive prescription medication without insurance. The list price of Trulicity is $886.36 per month without insurance, according to the manufacturer’s website. Trulicity prices may vary depending on the pharmacy you buy from.

Trulicity (dulaglutide), manufactured by Lilly, is a once-weekly injectable medication used to treat type 2 diabetes. Trulicity is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means it helps stimulate insulin production and decrease blood sugar levels. If you have type 2 diabetes, you may be able to lower your blood sugar levels with Trulicity. In addition, Trulicity has shown that it can reduce the risk of major cardiovascular events, such as heart attack and stroke, so it is also FDA-approved for the treatment of Type 2 diabetes and heart disease.

Trulicity is usually taken once weekly, and the dosage may be increased after four weeks. The starting dose is typically 0.75 mg, but your doctor will determine the right dosage for you based on your blood sugar levels and how well you respond to the medication. Trulicity is injected under the skin, usually in the thigh, abdomen, or upper arm.

Some common side effects of Trulicity include nausea, vomiting, diarrhea, and skin reactions at the injection site. In rare cases, more serious side effects can occur, such as heart problems, pancreatitis, and thyroid tumors. It’s important to speak with your doctor if you experience any troubling or unusual side effects while taking Trulicity. Learn more about Trulicity side effects and how to avoid them.

If you’re looking for a way to lower your blood sugar levels without insurance, Trulicity may be an option for you. However, it’s important to talk to your doctor about how Trulicity can best help manage your type 2 diabetes symptoms and whether it’s the right treatment option for you.

There is no generic version of Trulicity available at this time, so you may need to pay the full list price for Trulicity if you do not have insurance.

Is Trulicity covered by my insurance plan?

Trulicity was initially approved by the FDA (U.S. Food and Drug Administration) in 2014 as a treatment for type 2 diabetes. It is not approved for type 1 diabetes. While Trulicity is often covered by many insurance plans, coverage varies depending on your plan and provider. Contact your health insurance company to verify coverage and reimbursement for Trulicity before starting treatment.

Some commercial insurance plans, Medicare Part D plans, and Medicare Advantage may cover Trulicity. Most health insurance companies will require that you obtain prior authorization or may prefer that you use an alternative drug before covering Trulicity for diabetes.

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How much does Trulicity cost without insurance?

Lilly, the manufacturer of Trulicity, states on its website that the list price (cash price without insurance) for Trulicity is $886.36 per month. That works out to around $222 per week, depending on the dose prescribed by your healthcare provider.

If you do not have insurance or if Trulicity is not covered by your health insurance plan, the cost of Trulicity can be expensive and there is no generic Trulicity available at this time so you will need to purchase the brand-name medication. Fortunately, some options are available that can help you save on the cost of Trulicity.

Eli Lilly, the manufacturer of Trulicity, offers a savings card that can reduce the cost of your Trulicity prescription. You may be eligible to pay as little as $25 for 12 Trulicity pens with the Trulicity Savings Card. If the card was emailed to you, it does not need to be activated. However, if the card was given to you by your doctor, it needs to be activated. The manufacturer also states that patients must have insurance coverage for Trulicity through their commercial prescription drug insurance coverage to pay as little as $25 for up to 12 pens of Trulicity, and this offer is also subject to a maximum monthly limit of $150, as well as a separate maximum annual limit of $1800. The eligibility requirements may change so always check for the latest guidelines on Lilly’s website.

Do not take any over-the-counter medications or supplements as a substitute for prescription drugs to control blood sugar levels.

Compare Trulicity alternative prices

Brand-drug name (chemical name)Average weekly cost
Ozempic (semaglutide)$200 average weekly cost (1 dose weekly)
Bydureon BCise (exenatide)$200 average weekly cost (1 dose weekly)
Byetta (exenatide)$190 average weekly cost (2 doses daily)
Victoza (liraglutide)$210-310 weekly cost (1 dose daily)
Rybelsus (semaglutide)$310 weekly cost (1 dose daily)
Adlyxin (lixisenatide)$165 weekly cost (1 dose daily)

Note: Prices are provided as estimates only and are subject to change.

RELATED: Ozempic vs Trulicity

How to save on Trulicity without insurance

With an estimated annual cost of around $10,600, Trulicity can be a very expensive medication, especially for uninsured individuals. Fortunately, there are several options available to save money. Here are some tips on how you can save money on Trulicity:

  • Check if you have insurance drug coverage for Trulicity. If you do, your medical insurance may help cover some or all of the costs for this prescription drug if it is covered under the approved prescription drug formulary.
  • Research prices at multiple local pharmacies for the best price including mail-order pharmacies that ship to your location. A study conducted by Consumer Reports estimates that the retail prices for medications can vary by as much as 10 times from one pharmacy to another, even in the same city.
  • Try using a Trulicity manufacturer coupon or prescription drug discount card.
  • Get a health insurance plan that covers the cost of Trulicity. The insurance premium or co-pay costs will likely be a lot less than the cash price of Trulicity. Make sure to verify that the health insurance plan covers the cost of Trulicity for diabetes prior to signing up.
  • Check if you qualify for enrollment in any patient assistance programs offered by the manufacturer or other organizations. Patient assistance programs provide free or discounted drugs to people who cannot afford them.
  • You may also be eligible for Extra Help. Extra Help is a program from the Social Security Administration that helps people with limited incomes and resources pay for their Medicare prescription drug costs. To see if you qualify for Extra Help, visit the Social Security Administration’s website or call 1-800-772-1213.
  • Enroll in Medicaid if you are eligible. Medicaid is intended to help eligible individuals who are low-income and cannot afford their medications. Some Medicaid plans may cover the cost of Trulicity.
  • Get medical advice from your healthcare provider about alternative treatment options. Trulicity is a prescription drug that belongs to a drug classification called GLP-1 agonists which are used to treat type 2 diabetes. There are several lower-cost alternative drugs that your healthcare provider may consider to help you save money on your treatment.

How much does Trulicity cost with Medicare?

In 2022, the manufacturer’s (Lilly) website states that the list price of Trulicity is $886.36 per month without insurance.  Around 70% of people who have prescription insurance through Medicare pay between $0-100 per month, and the remaining people pay an average of $207 per month, according to Lilly, the manufacturer of Trulicity. The manufacturer also states that some people with Medicare who qualify for Extra Help will expect to pay $4 to $9 for each Trulicity prescription.

The amount an individual pays for Trulicity depends on various factors such as:

  • the type of Medicare coverage
  • the formulary tier (list of covered drugs in the plan)
  • whether the individual has reached their annual deductible amount
  • coinsurance or copayments

What is Trulicity?

Trulicity (dulaglutide) is an FDA-approved, once-weekly injectable prescription medication used to improve blood sugar control in adults with type 2 diabetes. Trulicity is a non-insulin prescription medication that helps your body release the insulin that it is already making. It is not used to treat type 1 diabetes and is only used for the treatment of type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide (GLP-1) receptor agonists. GLP-1 drugs stimulate the release of insulin in response to high blood sugar levels. They also slow the emptying of the stomach to help control hunger.

Trulicity is available in two strengths: 0.75 mg and 1.5 mg. It is injected under the skin (subcutaneously) with a pre-filled pen or syringe once weekly. The recommended starting dose is 0.75 mg once weekly for at least four weeks, after which it can be titrated up to the maximum dose of 1.5 mg per week based on blood sugar levels and other factors. It is important to note that Trulicity should always be taken once weekly on a fixed schedule, either at the same time each day or within the same hour each week.

Trulicity works by stimulating insulin release from the pancreas and inhibiting stomach emptying, which helps to keep blood sugar levels under control. In addition, Trulicity is associated with weight loss in some people. However, it is important to be aware that Trulicity can cause serious side effects such as low blood sugar (hypoglycemia) and pancreatitis. It is recommended to obtain medical advice from your healthcare provider about the side effects of this prescription medication.

Is there a generic of Trulicity?

There is currently no generic version of Trulicity available on the market. Diabetics who need Trulicity to treat their condition will need to purchase the brand-name drug, Trulicity.

What’s the cheapest way to get Trulicity?

The cheapest way to get Trulicity will vary depending on insurance coverage and the pharmacy you use. However, some tips to get Trulicity at a lower cost include using a mail-order pharmacy, using a pharmacy that offers discounts, and looking for coupons or manufacturer rebates.

Trulicity is covered by many health insurance plans, Medicaid, and Medicare prescription drug plans, however, the out-of-pocket costs may vary by plan.

You may be able to save money by switching to a Medicare Advantage Plan that offers prescription drug coverage, or by enrolling in a Medicare Part D prescription drug plan.

Some people with Medicare who qualify for Extra Help should expect to pay from $4 to $9 for their Trulicity prescription, according to the manufacturer, Lilly.

You may also try asking your healthcare provider about the possibility of receiving a sample pack of Trulicity from the manufacturer. This could help you decide if Trulicity is the right diabetes medication for you before committing to paying for a full month’s supply.

Trulicity prescription costs are high, but there are often ways to help reduce the cost of prescription medications. For additional information, talk to your healthcare provider about your options and compare costs between different pharmacies to find the best price.

Does Medicare cover Trulicity?

Medicare Part A (hospital insurance) does not cover Trulicity because it is not a hospital-administered medication.

Medicare Part B (medical insurance) does not cover Trulicity because it is considered an outpatient medication.

Medicare Part D plans (prescription drug plans) and Medicare Advantage plans with prescription drug coverage (MAPDs) may cover Trulicity. However, the coverage and costs will vary depending on your specific insurance plan. To learn more about whether Medicare covers Trulicity, talk to your healthcare provider or contact Medicare directly for more information concerning your Medicare Part D coverage. They can help you determine what level of coverage is available for this medication under your specific plan.

If an individual has Original Medicare and they would like coverage for Trulicity, they will need to enroll in a stand-alone Part D plan or a Medicare Advantage Prescription Drug (MAPD) plan that includes prescription drug coverage for Trulicity.

Medicare Part D plans and Trulicity coverage

Each Medicare plan has its own rules about how much it will cover for each type of drug in its formulary (list of covered drugs). Some plans may place Trulicity on a higher tier of their formulary (list of covered drugs), which means that patients will have to pay a higher coinsurance or copayment for the medication. Other plans may exempt Trulicity from the annual deductible amount.

If an individual has a Medicare Part D prescription drug plan or a Medicare Advantage Prescription Drug (MAPD) plan, they will likely pay a monthly premium, an annual deductible, and coinsurance or copayments for their Trulicity medication. The average monthly cost for a Medicare Part D prescription drug plan in 2022 is between $0-100 per month, and the remaining people pay an average of $207 per month, according to Lilly, the manufacturer of Trulicity. No Medicare drug plan may have a deductible of more than $480 in 2022 which means that you are responsible for the first $480 of out-of-pocket costs for your prescription drugs before your coverage commences.

Medicare Part D prescription drugs are the most common way of obtaining coverage from Medicare for prescription drugs such as Trulicity. If an individual has Medicare Part D, also called prescription drug coverage, they may be able to get Trulicity at a lower cost. Part D plans have a list of covered drugs (formulary drug list) and use tiered formularies. The cost of Trulicity depends on which tier the drug is placed in.

There are four tiers:

  • Preferred or Generic (lower-cost drugs)
  • Non-preferred or Brand-name (higher-cost drugs)
  • Specialty (very high-cost drugs)
  • Not Covered Drugs

Trulicity and Medicare Advantage

Medicare Advantage plans (Medicare Part C) are an alternative to the Original Medicare. If an individual has a Medicare Advantage plan that includes prescription drug coverage, they may be able to get Trulicity at a lower cost. Like with Part D plans, the cost of Trulicity will depend on which tier the drug is placed in and whether the individual has met their deductible. To see what your specific insurance plan covers, you can view your insurance plan’s formulary or contact your plan’s customer support department.

You can also compare Medicare Advantage plans that include prescription drug coverage on the Medicare website. When you compare plans, be sure to look at the total cost of the plan, not just the monthly premium. You should also consider whether the plan covers your preferred pharmacies and doctors.

Can Medigap plans help me save money on Trulicity?

No, Medicare Supplement Insurance (Medigap) cannot be used to help pay for prescription drugs. Medigap plans are supplemental insurance plans that can help cover some of the costs that Original Medicare does not cover, such as copayments, coinsurance, and deductibles. While Medigap plans cannot help with the cost of Trulicity specifically, they can help with some of the other costs associated with Medicare.

How much does Trulicity cost with Medicare?

The cost of Trulicity will vary depending on a number of factors, including insurance coverage and the pharmacy you use.

The manufacturer states that around 70% of people who have Medicare Part D pay between $0-100 per month, and the remaining people who have Medicare Part D pay an average of $207 per month. The manufacturer also states that some people with Medicare who qualify for Extra Help should expect to pay from $4 to $9 for their Trulicity prescription.

Trulicity assistance for Medicare patients

If you have Medicare and need help paying for Trulicity, there are a few options that may be able to help.

  • With the Trulicity Savings Card, you may be eligible to pay as little as $25 for 12 Trulicity pens.  To see if you qualify, visit the manufacturer’s website or speak with your doctor.
  • Patient Assistance Programs (PAPs) are also available to help you pay for Trulicity.
  • You may also be eligible for Extra Help. Extra Help is a program from the Social Security Administration that helps people with limited incomes and resources pay for their Medicare prescription drug costs. To see if you qualify for Extra Help, visit the Social Security Administration’s website or call 1-800-772-1213.
  • If you cannot afford your medication, your doctor may be able to provide you with samples of Trulicity from the manufacturer.

Vyvanse and coffee: is mixing them safe?

Vyvanse and coffee are both Central Nervous System stimulants, meaning that they increase mental and physical alertness and concentration in people. Vyvanse is a prescribed stimulant drug used to treat Attention Deficit Hyperactivity Disorder and coffee is a widely consumed stimulant that is available to pick up in a supermarket.

Many ADHD patients will be familiar with using coffee and energy drinks as a coping mechanism for dealing with ADHD. Is drinking coffee while on Vyvanse safe? No interactions are found between caffeine and Vyvanse however, this does not necessarily mean no interactions exist.

What is Vyvanse?

Vyvanse is the brand name of lisdexamfetamine dimesylate, an amphetamine, and also belongs to a class of drugs known as Central Nervous System stimulants (CNS stimulants). This means it acts on your brain to increase activity and speed up mental and physical processes.

It is used to treat symptoms of

  • Adult ADHD (Attention Deficit Hyperactivity Disorder) and ADHD in children, 6 years of age and older
  • Moderate to severe binge eating disorder (BED) in adults

As a prescription stimulant medication, Vyvanse also falls into the category of a Schedule II controlled substance. This means there is a high potential of abuse with this drug leading to severe psychological and physical dependence. The FDA highlights this risk alongside possible heart and mental health problems, which is more likely to occur when these stimulant medications are taken.

How does Vyvanse work?

When you swallow Vyvanse, your body converts the active ingredient lisdexamfetamine into a substance called dextroamphetamine. The dextroamphetamine is transported to your brain in your blood. It passes into your brain where it causes molecules called neurotransmitters to be released.

Neurotransmitters are produced naturally in your brain and body. They are signal molecules that allow messages to travel from nerve to nerve, regulating brain activity and playing a role in thinking and behavior.

Vyvanse causes your brain to release more neurotransmitters, like dopamine, norepinephrine, and serotonin and slows down the speed at which they are recycled. This causes levels of neurotransmitters to build up in your brain and improve ADHD symptoms.

How does coffee work in the body?

Coffee stimulates the body’s central nervous system and increases the brain’s production of a neurochemical known as dopamine, just as Vyvanse does. This stimulation can cause a person to feel alert and to have an increase in energy levels.

Negative effects can sometimes occur with caffeine. People who have trouble sleeping can experience further sleep disturbances or insomnia.

Side effects of caffeine

Heavy caffeine intake is defined by The Mayo Clinic as four or more cups of coffee per day which is roughly the equivalent of 500 to 600 mg. High doses of caffeine may cause:

  • Insomnia
  • Palpitations
  • Irritability
  • Anxiety
  • Muscle shakes or tremors
  • Upset stomach

Vyvanse side effects

The most common side effects of Vyvanse in children, adolescents, and/or adults with ADHD are:

  • Anorexia
  • Anxiety
  • Dizziness, nausea
  • Dry mouth
  • Irritability
  • Insomnia
  • Weight loss
  • Increased heart rate

Using caffeine with ADHD medications

As you can see the side effects of Vyvanse and caffeine are very similar. A person taking both amphetamines and caffeine will also get a double dose of their side effects. Both coffee and Vyvanse increase dopamine, and a person may begin to experience adverse side effects because of too much dopamine in the brain Both drugs can cause anxiety, difficulty sleeping, nausea, and stomach pains.

When caffeine and Vyvanse combine, they cause a synergistic effect. This happens when two drugs have additive mechanisms of action, making their combined effect more powerful. Caffeine makes amphetamines more effective, so a person taking Vyvanse, would likely feel a stronger impact depending on the amount of caffeine they consumed.

Studies have suggested that people with ADHD may have lower levels of dopamine transporters. That is why coffee, or caffeine, is said to help people with ADHD.

Caffeine and Vyvanse also act as vasoconstrictors. This means that they help in making the blood vessels smaller, which reduces the blood flow and helps in relieving headache symptoms. So, in this sense, both caffeine and Vyvanse have similar effects in controlling blood flow to treat ADHD. Caffeine has very similar properties to Vyvanse and how it treats ADHD.

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If you want to drink coffee what can you do?

If you’re a real coffee lover, you could start with a small dose of coffee while on Vyvanse and see how your body responds. You can gradually increase the amount of coffee you drink while on Vyvanse, but it is highly recommended not to go overboard. Always consult your doctor.

Understanding how much caffeine is present in various drinks is useful if coffee is not something you can give up. Be mindful that the actual caffeine content of a cup of coffee can vary by brand. The Mayo Clinic gives these amounts as a guide:

  • 8oz of brewed coffee contains 96mg of caffeine
  • 1oz of espresso coffee contains 64mg of caffeine
  • 8oz of instant coffee contains 62mg of caffeine

Does decaf coffee mean it contains no caffeine?

No. Decaf coffee does contain caffeine but much less than regular coffee. For example, decaf coffee typically has 2 milligrams in an 8-ounce cup, and brewed coffee has 96 milligrams in an 8-ounce cup. If you react strongly to caffeine in a negative way, you may want to avoid these beverages altogether.

Can children consume caffeine?

We recommend you consult with your health care provider for advice regarding your child’s caffeine consumption.

Final word

Factors such as body weight, medications you may take, and individual sensitivity will determine how much coffee is too much for you. If you are taking Vyvanse for ADHD treatment and want to consume coffee then an easy swap may be to decaf coffee. However, if that’s not for you then speak to your prescribing healthcare provider for medical advice on how to consume coffee when taking an amphetamine such as Vyvanse, Adderall (amphetamine and dextroamphetamine), Concerta (methylphenidate ER), or Ritalin (methylphenidate). Always inform your pharmacist about any medications you are taking including over-the-counter meds and supplements.

Vraylar side effects and how to avoid them

Vraylar is the brand name of an antipsychotic drug also known as an atypical antipsychotic drug. It is used to treat bipolar depression for short-term or long-term treatment. Vraylar can cause adverse effects. The most common tend to be drowsiness to more serious movement disorders and worsening mental health. Learn more about the most common Vraylar side effects and how to avoid them.

What is Vraylar?

Vraylar is the brand name of an FDA-approved antipsychotic medication. It is prescribed to adults to treat manic and depressive episodes caused by bipolar I disorder, as well as manic episodes caused by schizophrenia.

Bipolar disorder, previously called manic depression, is a mental disorder. It causes periods of both depressed mood and elevated mood, called mania. During depressed moods, you can feel down and sad, numb, get no pleasure from pastimes you usually enjoy, feel irritable and guilty, and have trouble sleeping. During periods of mania, you can feel high, elated, invigorated, wired, and jumpy, thoughts and feelings can come in quick bursts, and you may feel more impulsive and engage in risky behaviors. You can also have mixed episodes where you get symptoms of both depression and mania at the same time.

Schizophrenia is a mental disorder that also causes episodes of mania. These episodes may also involve psychosis – periods where you lose your connection to reality, you can see and hear things that aren’t really there and have delusional thoughts. Both bipolar disorder and schizophrenia are thought to be caused by a mix of genetics and life events that can disrupt your natural brain chemistry. Imbalances in naturally occurring chemicals, like dopamine, may lead to the highs and lows that can cause periods of depression or mania.

There are no known cures for bipolar disorder or schizophrenia, but medications like Vraylar can help you manage your disorder. Vraylar can balance your levels of dopamine and can reduce your depressive and manic symptoms.

Vraylar active ingredients

The active ingredient in Vraylar is called cariprazine. It helps with schizophrenia and bipolar disorder by regulating how your brain responds to dopamine.

Dopamine is a chemical you produce naturally. It helps your brain cells send and receive signals, and it assists with regulating aspects of your brain function. When you take Vraylar, the active ingredient cariprazine binds with areas on the outside of the cells in your brain called dopamine receptors. This stimulates the effect of dopamine on your brain cells, but to a lesser degree than actual dopamine. If you have low dopamine levels, cariprazine acts as if it’s boosting your dopamine. If you have high dopamine levels, cariprazine acts as if it’s reducing them. This can balance your response to dopamine, and has been shown to reduce both depressive and manic symptoms, even when they occur at the same time.

How do you take Vraylar?

Vraylar comes as a capsule that is swallowed with or without food or water. If you miss a dose of Vraylar, take it as soon as you remember. If it’s almost time for your next dose, you can skip your missed dose. Store this medicine in its original packaging at room temperature, away from moisture, heat, and light

Vraylar possible side effects

All medications can have side effects. It’s important to note that not everyone will experience side effects, or get the same ones if they do. The most common side effects of Vraylar include:

  • Headaches
  • Feeling lightheaded
  • Sleepiness
  • Indigestion
  • Abdominal pain
  • Constipation
  • Nausea and vomiting
  • Weight gain
  • Feeling restless and that you need to move around (akathisia)
  • Tremors
  • Difficulty moving and/or slow movements

In rare instances, Vraylar can cause more serious side effects, including:

  • Allergic reactions to the medication
  • An increased risk of suicidal thoughts and behaviors in children and young adults (see the boxed warning)
  • Increased risk of death and strokes in elderly or older adults with dementia-related psychosis. Vraylar should not be given to patients with dementia-related psychosis (see boxed warning)
  • Worsening mental health symptoms
  • Neuroleptic malignant syndrome (NMS) – rare but sometimes fatal reaction that can cause fever, muscle stiffness, sweating, confusion, and changes in breathing, blood pressure, and heart rate
  • Uncontrolled body movements (known as extrapyramidal disease or tardive dyskinesia)
  • High blood sugar and diabetes
  • Increased levels of fat in your blood, like cholesterol and triglycerides
  • Low blood pressure when rising from sitting or lying down (orthostatic hypotension)
  • Low white blood cell count (leukopenia)
  • Seizures
  • Increased body temperature
  • Difficulty swallowing

How to avoid Vraylar side effects

1. Discuss medical history and medications

Discussing your medical history with your prescribing healthcare provider is important to help them understand how well Vraylar will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will also allow them to pick up any drug interactions with Vraylar that may increase possible side effects.

2. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional. Stick to the same timing for taking your medication and taking it consistently will make a big difference in how well Vraylar works for you. Consider setting an alarm on your phone as a reminder or putting it in your diary as a daily task.

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Refer to the medication guide for more drug information.

Do not abruptly stop taking your medication or reduce your recommended dose before talking to your doctor as this may result in withdrawal symptoms.

3. Keep cool

Your body temperature may fluctuate when taking Vraylar, particularly when exercising or in hot weather. To avoid this keep cool and stay hydrated. Keep a water bottle with you and refill it on a regular basis.

4. Avoid alcohol

Alcohol may worsen any side effects you may experience. Read our blog on mixing bipolar and alcohol for more information.

5. Pay attention to your body

Paying attention to how your body feels when taking Vraylar is important, taking particular attention to worsening symptoms or new symptoms. Talk to your doctor straight away for medical advice if you start to experience any side effects of Vraylar when taking it.

Vraylar drug interactions

Vraylar can interact with other medications, specifically:

  • Strong CYP3A4 inhibitors, such as itraconazole or ketoconazole
  • CYP3A4 inducers, such as rifampin or carbamazepine

This can change how Vraylar and the other medications work and can make some side effects more likely.

Vraylar warnings & precautions

Vraylar is not suitable for everyone. Do not take Vraylar if you:

  • Are allergic to the active ingredient cariprazine
  • Are allergic to any of the other ingredients in Vraylar
  • Are under 18 years of age
  • Have dementia-related psychosis – antipsychotic medications can put you at an increased risk of death and stroke

Talk to your physician before taking Vraylar if you:

  • Are taking any medications that can interact with Vraylar (listed in the section above)
  • Have previously had a stroke
  • Have or have had any heart problems
  • Have or have had any kidney problems
  • Have or have had any liver problems
  • Have or have had seizures
  • Have or have had a low white blood cell count
  • Have high total cholesterol, LDL cholesterol, triglycerides, or low HDL cholesterol
  • Have diabetes, or have a history of diabetes in your family
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known whether Vraylar is present in human breast milk

Vraylar can cause sleepiness, dizziness, and confusion, which can impair your ability to drive, use machinery, or perform other dangerous tasks. You should avoid these activities when taking Vraylar until you’re confident Vraylar doesn’t give you these side effects.

FDA approves the first Eliquis generic, apixaban

Good news for people who are at high risk for stroke or are suffering from deep vein thrombosis (DVT) or pulmonary embolism (PE). The FDA (U.S. Food and Drug Administration) has approved the first Eliquis generic, apixaban, which will be a lower-cost blood thinner alternative. Generic Eliquis will be much more affordable than the brand-name drug once it’s available for sale. The initial FDA approval for the generic versions of Eliquis was provided to generic drug manufacturers, Micro Labs Limited and Mylan Pharmaceuticals, Inc.

What is Eliquis?

Eliquis (apixaban) is a blood thinner (anticoagulant) that is used to:

  • reduce the risk of stroke and blood clots in people who have atrial fibrillation (a heart rhythm disorder)
  • treat deep vein thrombosis (DVT) and pulmonary embolism (PE)
  • reduce the risk of DVT and PE happening again

It works by blocking a protein called Factor Xa. This protein is needed for blood clotting.

Eliquis is manufactured by Bristol-Myers Squibb and marketed by Pfizer. It was first approved by the FDA in 2012.

Is there a cheaper alternative to Eliquis?

Eliquis was the third blood thinner to be approved by the FDA. This approval was followed by two other alternative anticoagulants, Pradaxa (dabigatran) and Xarelto (rivaroxaban). However, this is the FDA’s first approval of a generic for Eliquis (apixaban).

Oral anticoagulants such as Coumadin (warfarin) have been commonly replaced by Eliquis and Xarelto. Warfarin requires much more careful screening and monitoring for potential drug interactions which may be serious. Fortunately, people who are prescribed Eliquis do not need this extra monitoring including multiple blood tests which will enable greater access to this drug.

RELATED: Eliquis alternatives: which other blood thinners can I take?

What type of blood clotting does Eliquis treat?

Doctors may prescribe Eliquis for the following indications, according to the FDA:

  • Reducing the risk of stroke and non-central nervous system (non-CNS) systemic embolism in adult patients with atrial fibrillation (AF)
  • Treating and preventing deep vein thrombosis (DVT) and pulmonary embolism (PE) in adults
  • To prevent venous thromboembolic events (VTE) in adult patients who have undergone hip or knee replacement surgery
  • To reduce the risk of recurrent VTE after an initial VTE event

Blood clots are a serious condition, and possibly life-threatening, that can lead to strokes, heart attacks, and even death. Eliquis is a life-saving medication for people who are at risk for these types of events.

Is there a generic for Eliquis available yet?

There is currently no generic for Eliquis available yet in the United States.

How much will the generic cost?

The Eliquis generic name is apixaban. The price of generic apixaban has not been announced yet. However, it will likely be much cheaper than the brand-name drug, which costs around $529 for a 30-day supply, according to the manufacturer’s website.

When will generic Eliquis be available?

The FDA has not announced a specific date when generic Eliquis will be available so there is no Eliquis generic release date at this time. It normally takes several months for a generic to be available for sale following the generic approval, however, the U.S. Patent and Trademark Office had granted Eliquis extended protection on its patent. The Bristol Myers Squibb-Pfizer Alliance recently announced in a press release that the earliest that generic manufacturers are permitted to launch their apixaban products is April 1, 2028, subject to additional appeals and challenges.

How do you take Eliquis?

Eliquis is taken orally, with or without food. It is available as a 2.5mg tablet and 5mg tablet. The usual dose is:

  • 5 mg twice daily for those who have atrial fibrillation and are also 75 years old or older, have a lower body weight (less than 60 kg), or have certain kidney problems
  • 2.5 mg twice daily for all other patients with atrial fibrillation
  • 5 mg twice daily for those who are treating DVT or PE, and also have a Creatinine Clearance of 15-29 mL/min
  • 2.5 mg twice daily for all other patients treating DVT or PE

Your doctor may adjust your dose depending on your individual situation.

What are the side effects of Eliquis?

The most common side effects of Eliquis are:

  • bleeding
  • bruising
  • nosebleeds
  • indigestion
  • diarrhea

You may have a higher risk of bleeding if you take Eliquis with other medicines that increase your risk of bleeding (including over-the-counter medications), such as aspirin, heparin, warfarin, nonsteroidal anti-inflammatory drugs (called NSAIDs), selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), or other medicines to help prevent or treat blood clots

These are not all of the possible side effects of Eliquis. You should always seek the medical advice of a licensed healthcare provider for any questions or concerns relating to your medical condition or treatment.

How much does Eliquis cost?

In 2022, the manufacturer’s (Bristol-Myers Squibb) website listed the price of Eliquis as $522 for a 30-day supply without insurance. People who have prescription insurance through Medicare pay $37 on average for Eliquis, according to the manufacturer of Eliquis. The manufacturer also states that some Medicare patients with Part D coverage may pay as little as $10 per month for Eliquis through the use of a Medicare Part D prescription drug plan or a Medicare Advantage plan that includes prescription drug coverage.

Why is Eliquis so expensive?

Eliquis is so expensive because it is a brand-name medication. Brand-name drugs are always more expensive than generic drugs. In contrast, the FDA-approved generic version of Eliquis (apixaban) will be much cheaper. There are several alternatives to Eliquis that you may consider and speak to your doctor to find out if any of these alternatives are medically appropriate for you.

How much is Ozempic without insurance?

Ozempic prices can be very expensive without insurance. The list prices for Ozempic® 0.25 or 0.5 mg (1 x 1.5-mL pen) and 1 mg (1 x 3-mL pen) are $851.60, according to the manufacturer’s website. However, prices may vary depending on the pharmacy you visit.

Learn more on how you can obtain the lowest price for Ozempic and alternative treatments which are available.

Ozempic (semaglutide), manufactured by Novo Nordisk, is a popular brand-name prescription drug that is used to treat type 2 diabetes. Ozempic is not intended to be used to treat Type 1 diabetes. Ozempic is part of a class of drugs known as GLP-1 receptor agonists. Ozempic works by helping your body release more insulin and improving blood sugar control.

Ozempic is typically taken once a week by injection, either under the skin or into a muscle. The Ozempic pen is prefilled with the correct amount of medication for one injection.

You may start to see improvements in your blood sugar control within a few weeks of starting treatment with Ozempic, but it may take up to two months to see the full effect.

Ozempic is usually taken for long-term treatment of diabetes. Once you start taking Ozempic, you will likely need to take it for the rest of your life.

Common side effects of Ozempic include nausea, diarrhea, constipation, indigestion, low blood sugar levels (hypoglycemia), and reactions at the injection site. In rare instances, this drug may cause low hypoglycemia or blood sugar. Speak to your healthcare provider if you experience any serious allergic reactions while taking Ozempic.

There is no generic version of Ozempic available yet so you may need to pay the full price if you do not have insurance.

Ozempic is not FDA-approved for weight loss. However, some people may lose weight while taking Ozempic because the drug will lower blood sugar levels and improve glycemic control. When blood sugar levels are well-controlled, it can lead to weight loss in some people with type 2 diabetes.

Is Ozempic covered by my insurance?

Ozempic was initially approved by the FDA (Food and Drug Administration) in December 2017 as a treatment for diabetes type 2.

Ozempic may be covered by your insurance plan if it is used to treat diabetes. However, coverage and reimbursement for Ozempic can vary depending on each individual insurance plan. Contact your insurance company to verify coverage and reimbursement for Ozempic before you start treatment.

Some commercial insurance plans, Medicare Part D prescription drug plans and Medicare Advantage may cover Ozempic. Most health insurance companies may require you to obtain prior authorization or may prefer that you use an alternative drug before covering Ozempic.

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How much does Ozempic cost without insurance?

The manufacturer’s website states that the list prices (cash price without insurance) for Ozempic® 0.25 or 0.5 mg (1 x 1.5-mL pen) and 1 mg (1 x 3-mL pen) are $851.60. That works out to around $213 per week depending on the prescribed dose.

Many health insurance plans may cover some of the cost of Ozempic, however, the copay will vary by plan. You may still be responsible for a portion of the cost, depending on your insurance coverage.

If you do not have insurance or if Ozempic is not covered by your insurance plan, the cost of Ozempic can be expensive. Fortunately, there are some ways to save on the cost of Ozempic.

Novo Nordisk, the manufacturer of Ozempic, offers a savings card that can reduce the cost of Ozempic by up to $100 per month. Eligible patients who have private or commercial insurance, such as insurance received through an employer, may be eligible to pay as little as $25 for a 1, 2, or 3-month prescription. Novo Nordisk states the maximum savings of $150 per 1-month prescription, $300 per 2-month prescription, or $450 per 3-month prescription). The savings card is valid on prescriptions for a 1, 2, or 3-month supply, and can be used for up to 24 months from the date of activation. These eligibility requirements may change and it is recommended to check for the latest guidelines on the manufacturer’s website.

Individuals without insurance should also ask their healthcare provider about Ozempic alternatives that are available as lower-priced generics. Examples of lower-priced antidiabetic generic drugs are metformin, meglitinides, sulfonylureas, bile acid sequestrants, and alpha-glucosidase inhibitors. These lower-cost generic drugs are approved by the FDA for lowering blood glucose. However, these alternatives may not be considered an adequate substitute for Ozempic. Speak with your healthcare provider to determine if there are any lower-cost alternative drugs for you.

Do not take any over-the-counter medications or supplements as a substitute for prescription drugs to control blood sugar levels.

Compare Ozempic alternative prices

Brand-drug name (chemical name)Average weekly cost
Adlyxin (lixisenatide)$300 average weekly cost (1 dose daily)
Bydureon BCise (exenatide)$190 average weekly cost (1 dose weekly)
Byetta (exenatide)$190 average weekly cost (2 doses daily)
Victoza (liraglutide)$210-310 weekly cost (1 dose daily)
Trulicity (dulaglutide)$300 weekly cost (1 dose weekly)
Rybelsus (semaglutide)$310 weekly cost (1 dose daily)

Note: Prices are provided as estimates only and are subject to change.

RELATED: Ozempic vs Trulicity

How to save on Ozempic without insurance

With an estimated annual cost of around $10,000, Ozempic can be a very expensive drug, especially for those without insurance. However, there are several options available to save money. Here are some tips on how you can save money on Ozempic:

  1. Consider Compounded Semaglutide which is the compounded version of Ozempic
  2. Check if you have insurance coverage for Ozempic. If you do, your medical insurance may help cover some or all of the costs.
  3. Shop around at multiple pharmacies for the best price including mail-order pharmacies. A study conducted by Consumer Reports estimates that the retail prices for medications can vary by as much as 10 times from one pharmacy to another, even in the same city.
  4. Try using an Ozempic coupon or prescription drug discount card.
  5. Get a health insurance plan that covers Ozempic. The insurance premium costs will likely be a lot less than the cash price of Ozempic. Make sure to verify that the health insurance plan covers Ozempic.
  6. See if you qualify for any patient assistance programs offered by the manufacturer or other organizations. Patient assistance programs provide free or discounted drugs to people who cannot afford them.
  7. Enroll in Medicaid if you are eligible. Medicaid is intended to help eligible individuals who are low-income and cannot afford their medications. Some Medicaid plans may cover the cost of Ozempic.
  8. Get medical advice from your healthcare provider about alternative treatment options. Ozempic is a prescription drug that belongs to a drug classification called GLP-1 agonists which are used to treat type 2 diabetes. There are several lower-cost alternative drugs that your healthcare provider may consider to help you save money on your treatment.

How much do prescription drugs cost without insurance?

Individuals without insurance will generally pay the list price set by the pharmaceutical manufacturer. Prescription drug prices in the United States are amongst the highest in the world and continue to rise. Americans spend on average $1228.86 per year on prescription drugs, according to the OECD.

The cost of prescription drugs can vary greatly from one pharmacy to another. There are also a number of ways to save on prescription drugs, such as using coupons, prescription drug discount cards, prescription assistance programs, or ordering medications through mail-order pharmacies. Learn more about how much prescription drugs cost without insurance and how to get the best price on your medication.

How much do prescription drugs cost?

See below the average monthly out-of-pocket costs for the 10 most popular prescription drugs in the United States.

ConditionGeneric drugEstimated monthly costBrand-name drugEstimated monthly cost
Cholesterolatorvastatin calcium 20mg$10Lipitor 20mg$500
Cholesterolrosuvastatin 10mg$10Crestor 10mg$300
GERDomeprazole 20mg$10Prilosec OTC 20mg$20
Seizuresgabapentin 300mg$5Neurontin 300mg$200
Depressionescitalopram 10mg$10Lexapro 10mg$400
Depressionfluoxetine 20mg$5Prozac 20mg$525
Hypertensionamlodipine besylate 10mg$5Norvasc 10mg$320
Hypertensionlosartan 50mg$10Cozaar 50mg$120
Blood clotsclopidogrel 75mg$10Plavix 75mg$200
Asthmamontelukast 10mg$10Singulair 10mg$250

Why are prescription drugs so expensive?

There could be several reasons why a particular prescription drug may be expensive:

The drug is new and there is no generic drug available

If there are no FDA (Food and Drug Administration) approved generic equivalents available for your medication, you will likely have to pay the brand-name price. New drugs, especially those that treat complex conditions like cancer or hepatitis C, can be extremely expensive.

A drug comes off-patent when the exclusivity period expires. This typically happens 20 years after the drug is first patented. After a drug comes off-patent, other drug manufacturers can make and sell generic versions of the drug. However, if there are no generic manufacturers for a particular drug, the price will remain high.

While brand name and generic drugs are equally as effective, there may be differences such as:

  • Color
  • Shape
  • Packaging
  • Dosage form (e.g. pill, capsule, patch, etc.)
  • Taste
  • Inactive ingredients
  • Flavorings

There is only one manufacturer

When there is only one manufacturer for a particular drug, that drug company can set the price as high as it wants.

Where the prescription drug is purchased

The prices of prescription drugs vary by pharmacy. For example, drugs purchased through mail-order pharmacies or online pharmacies may be cheaper than those purchased at a brick-and-mortar pharmacy. Local pharmacies may not necessarily have the lowest price for your medication.

A survey by Consumer Report concluded that drug prices could vary by as much as 10 times in the same city, so it is advisable to shop around for the lowest prices.

Why do medications cost so much without insurance?

Uninsured patients will generally need to pay the cash price for their prescription drugs. The cash price is the full price that a pharmaceutical company charges for a drug. If there is no generic drug alternative for your medication, the cash price for the brand-name drug could potentially be very high.

Are prescription drugs always cheaper with insurance?

Not necessarily. It may make financial sense to purchase the medication for cash, as the drug may not be covered under the health insurance company’s formula, you may not have met your deductible, or the cash price may be cheaper than the insurance copay. You may be better off buying the medication for the cash price without insurance if:

The drug is not covered in the health insurance company’s formulary

The health insurance company’s formulary may not cover the cost of the medication, meaning that the patient would need to pay for the entire cost of the drug.

You have not yet met your deductible

If you have not yet met your deductible, you will be responsible for paying the entire cost of the medication until you reach your deductible.

Your insurance company has high copays for the drug

Even if the medication is covered under the health insurance company’s formulary, you may be responsible for a high copay or coinsurance. In this case, it may make financial sense to pay the cash price for the medication.

In some cases, a pharmaceutical company will give a PBM a monetary incentive to choose their brand name version, which is more expensive, instead of the cheaper generic version which is cheaper for the patient. This kickback is known as a “clawback” when the PBM makes more money while the insured patient is required to pay a higher copay. Check with your healthcare provider if there is a generic alternative for the best price on your medication.

Which prescription drugs are the most expensive?

The most expensive prescription drugs are most commonly known as biological drugs which are breakthrough treatments for life-threatening or serious conditions. Biological drugs been genetically engineered or derived from living cells to treat diseases. They are often very effective, but also very costly.

Some examples of the most expensive prescriptions drugs are:

Zolgensma – Annual cost: $2,125,000

Zolgensma, manufactured by Novartis Gene Therapies EU Limited, is a gene therapy medication used to treat spinal muscular atrophy a rare disease that can cause respiratory issues, paralysis and progressive loss of movement. An annual supply of Zogensma costs around $2,125,000, or $177,000 a month.

Zokivny – Annual cost: $1,032,480

Zokivny is used to treat a rare and fatal genetic condition, Hutchinson-Gilford progeria syndrome, a condition that causes rapid aging in children. Zokivny, manufactured by Eiger BioPharmaceuticals, combats the buildup of harmful proteins and can extend the lives of those with progeria by up to two and a half years. An annual supply of this prescription medication is $1,032,480, or $86,040 a month.

Danyelza – Annual cost: $977,664

Danyelza, manufactured by Y-mAbs Therapeutics, Inc., is used to treat pediatric and adult patients with neuroblastoma in the bone or bone marrow, a rare form of cancer. Danyelza has an annual cost of $977,664, or $81,472 per month.

Who decides on the cost of prescription drugs?

Prescription drug prices are negotiated by pharmaceutical companies, pharmacy benefit managers and health insurance companies.

Pharmaceutical companies incur the research and development costs (R&D) associated with introducing a new drug to the market. They will manufacture and sell the drugs to patients.

Pharmacy benefit managers (PBMs) work in collaboration with health insurance companies and employers to administer their drug benefits. They negotiate discounts on the cost of the prescription drugs with the pharmaceutical companies, as well as rebates which provide favorable coverage for the pharmaceutical company’s drug, resulting in increased sales and utilization by patients who are covered by the health plan. These arrangements are not disclosed to patients. PBMs are known as the “middleman” between the pharmaceutical manufacturers, pharmacies, and insurance companies, influencing the insurance companies on which drugs to cover and how much patients will pay as part of their copay.

Health insurance companies will reimburse patients and/or their employers for a portion of the prescription drug costs. They are responsible for approving requests for treatment, setting the copays, and determining the prices with the PBMs which dictates how much covered patients will pay for the drugs.

Save money when buying prescription drugs without insurance

Fortunately, there are multiple options you can consider which may help you save money when purchasing your prescription drugs. While Americans are faced with the highest prescription drug prices in the world, there are still several ways to save on medications.

Generic drug alternatives

Always check if there is a generic alternative available for your medication as generic drug prices are generally much lower than brand-name drugs. Most brand-name drugs can be interchanged with generic drugs, with some exceptions such as drugs with a narrow therapeutic index. Speak with your healthcare provider to find out if there is a generic drug available for your treatment.

Mail-order pharmacies

Another way to save on prescription drugs is to use mail-order pharmacies. Many insurance companies have their own mail-order pharmacies and offer discounts for using them. The convenience of having medications delivered to your doorstep can be especially helpful for seniors or those with mobility issues.

Prescription drug discount cards

If you don’t have insurance, you can still get discounts on your prescription drugs by using a prescription drug discount card. These discount cards work by providing discounts on the cash price of medications at participating pharmacies.

Manufacturer coupons

Some pharmaceutical manufacturers may offer coupons or savings cards that can be used with or without insurance. These coupons can be found on the manufacturer’s website.

Prescription assistance programs

If you’re struggling to afford your medications, there are a number of prescription assistance programs that can help. These programs are usually run by pharmaceutical companies or non-profit organizations and can help cover the cost of medications for those who qualify.

Ask for a 90-day supply of medication

If you are taking a long-term maintenance medication, you may be able to save money by purchasing a 90-day supply of your medication instead of a 30-day supply.

How much does Xarelto cost with Medicare?

Without insurance, the cash price of Xarelto in 2022 is anywhere from $400-500 for a 30-day supply.  Patients who have prescription insurance through Medicare pay between $2-18 on average for Xarelto. The amount an individual pays for Xarelto depends on various factors such as:

  • Medicare coverage type
  • the insurer’s formulary tier list (list of covered drugs)
  • if the individual has reached their annual deductible amount
  • copayments or coinsurance

What is Xarelto?

Xarelto (rivaroxaban) is an anticoagulant (blood thinner) medication. The brand name Xarelto is owned by Bayer AG, Janssen Pharmaceuticals, Inc., and Johnson & Johnson.  In the United States, rivaroxaban was approved for medical use in 2011.

It works by inhibiting thrombin, a protein involved in the formation of blood clots. Xarelto is available as a tablet that can be taken by mouth with or without food.

Xarelto is used to:

  • prevent blood clots from forming in people who have undergone knee or hip replacement surgery
  • treat and reduce the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE)
  • reduce the risk of stroke and systemic embolism in people with nonvalvular atrial fibrillation

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Is there a generic version of Xarelto?

There is no generic version of Xarelto currently available in the United States. The earliest possible date that a generic version could be available is 2039, which is when the patent for Xarelto expires.

What’s the cheapest way to get Xarelto?

The best way to find the lowest price for Xarelto is to compare prices at different pharmacies. You can also try using a prescription drug discount card or prescription assistance programs. Manufacturer assistance programs help by providing discounts for eligible individuals. Other ways to save on Xarelto may include using a mail-order pharmacy or looking for a Xarelto coupon.

Some insurance plans may help with reducing the cost of Xarelto, but may also have higher copays, deductibles or premium fees. It’s always best to speak with your insurance company about coverage and costs before buying Xarelto.

You may be able to save money by switching to a Medicare Advantage Prescription Drug (MAPD) plan that includes prescription drug coverage, or by enrolling in a Medicare Part D prescription drug plan.

You may also try asking your healthcare provider for free Xarelto samples to help you decide if Xarelto is the right medication for you before purchasing.

Xarelto is an expensive medication but there are possible ways to reduce the cost.

Does Medicare cover Xarelto?

Medicare Part A (hospital insurance) does not cover Xarelto because it is not a hospital-administered medication.

Medicare Part B (medical insurance) does not cover Xarelto because it is considered an outpatient medication.

Medicare Part D plans (prescription drug plans) and Medicare Advantage plans with prescription drug coverage (MAPDs) may cover Xarelto.

If you have the Original Medicare and would like coverage for Xarelto, you may need to enroll in a stand-alone Part D plan or a Medicare Advantage Prescription Drug (MAPD) plan that includes prescription drug coverage.

Medicare Part D plans and Xarelto coverage

Medicare Part D plans (PDPs) and Medicare Advantage Prescription Drug (MAPD) plans are required to cover all FDA-approved drugs. Since Xarelto is an FDA-approved drug, it must be covered by all PDPs and MAPDs that offer prescription drug coverage.

Each plan has its own guidelines on what it will cover for each type of drug in its formulary (list of covered drugs). Some plans may also have Xarelto on a higher tier of their formulary (list of covered drugs), which may result in patients paying a higher coinsurance or copayment for the medication. Other plans may also exempt Xarelto from the annual deductible amount.

If an individual has a Medicare Part D prescription drug plan or a Medicare Advantage Prescription Drug (MAPD) plan, they will likely pay a monthly premium, an annual deductible, and coinsurance or copayments for their Xarelto medication. The average monthly premium for a Medicare Part D prescription drug plan in 2022 is $33, according to CMS. No Medicare drug plan may have a deductible of more than $480 in 2022 which means that you are responsible for the first $480 of out of pocket costs for your prescription drugs before your coverage commences.

Medicare Part D prescription drugs are the most common way of obtaining coverage from Medicare for prescription drugs such as Xarelto. If an individual has Medicare Part D, also called prescription drug coverage, they may be able to get Xarelto at a lower cost. Part D plans have a list of covered drugs (formulary drug list) and use tiered formularies. The cost of Xarelto depends on which tier the drug is placed in.

There are four tiers:

  • Preferred or Generic (lower-cost drugs)
  • Non-preferred or Brand-name prescription drugs (higher-cost drugs)
  • Specialty (very high-cost drugs)
  • Not Covered Drugs

If an individual has Medicare Part B, they may be able to get help with the costs of Xarelto through the Xarelto Savings Program. The Xarelto Savings Program offers free or low-cost medications to eligible patients. To see if you qualify for this program, visit the manufacturer’s website or speak with your doctor.

Xarelto and Medicare Advantage

Medicare Advantage plans (Medicare Part C) are offered by private insurance companies and are required to cover all of the same benefits as Original Medicare.

Some Medicare Advantage plans may also offer prescription drug coverage. If an individual has a Medicare Advantage plan that includes prescription drug coverage, they may be able to get Xarelto at a lower cost. Similar to Medicare Part D plans, the cost of Xarelto will depend on the tier of the drug in the formulary, and whether the individual has met their deductible amount yet. To see what your specific insurance plan covers, you can view your insurance plan’s formulary by contacting your insurance plan’s customer service department.

You may also compare Medicare Advantage plans that include prescription drug coverage on the Medicare website. When you compare plans, be sure to look at the total cost of the plan, not just the monthly premium.

Can Medigap plans help me save money on Xarelto?

No, Medigap plans do not cover prescription drugs.

Medigap plans are supplemental insurance plans that help cover some of the costs that Original Medicare does not cover. These plans do not cover prescription drugs, so they would not help an individual save money on Xarelto.

If you have a Medigap plan and are enrolled in a Medicare Part D plan or a Medicare Advantage Prescription Drug (MAPD) plan, your Medigap plan will not pay for any of the costs associated with your prescription drug coverage, including premiums, deductibles, coinsurance, and copayments.

How much does Xarelto cost with Medicare?

Medicare patients with Part D coverage pay on average $2-18 for Xarelto.

Xarelto assistance for Medicare patients

If you have been prescribed Xarelto and need help paying for the medication, there are a few options that may be able to help.

  • The Xarelto Savings Program offers low-cost medications to eligible patients. To see if you qualify for this program, visit the manufacturer’s website or speak with your doctor.
  • Patient Assistance Programs (PAPs) are programs offered by pharmaceutical companies to help patients who cannot afford their medications. Eligible patients may be able to get Xarelto for free or at a reduced cost.
  • You may also be eligible for Extra Help. Extra Help is a program offered by the Social Security Administration that helps eligible Medicare patients with the costs of prescription drugs, including premiums, deductibles, and coinsurance. To see if you qualify for Extra Help, visit the Social Security Administration website or call 1-800-772-1213. You can also contact your state’s Medicaid office to see if Extra Help is a program that helps people with limited income and resources pay for their prescription drugs.
  • Your doctor might be able to give you free samples of Xarelto to try. Doctors sometimes receive free samples from pharmaceutical companies to help their patients who cannot afford their medications.
  • There are also alternative medications available including Eliquis, Pradaxa and Savaysa.

 

24 hour pharmacy near me

If you are looking for a 24 hour pharmacy near you, there are a few ways to find one which we will list in this article.

We have listed the most popular 24-hr pharmacies in the United States. CVS, Walgreens, Rite Aid, Jewel-Osco, and Ralphs offer 24 hour pharmacy services at some locations.  As well, Albertsons, Giant Eagle, Hy-Vee, Kroger, Publix, Safeway and Walmart have late opening hours at some of their locations. You can use their store locator tool to find pharmacy locations near you. Most drugstores list their hours of operation and locations on their website.

Once you have found a 24 hour pharmacy near you, call them to make sure they are open and ask about their hours and health services.

Find a 24-hour pharmacy near me

Search for a 24 7 pharmacy near you by zip code or city. Go to Google Maps, enter keyword “pharmacy”, and change the hours of operation to 24/7.

Which major pharmacies are open 24 hours?

CVS

CVS pharmacy

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at some locations

CVS Pharmacy is one of the most popular pharmacy chains in the United States. 24-hour CVS locations can be found in most major cities. You can use their store locator tool to find a 24-hour CVS near you.

Walgreens

Walgreens pharmacy

Payment methods: Cash, credit, debit, gift cards and personal checks

Drive through option: Yes, at some locations

Walgreens Pharmacy is another large pharmacy chain in the United States. They also have 24-hour locations in most major cities. You can use their store locator tool to find a 24-hour Walgreens near you.

Rite Aid

Rite aid pharmacy

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at some locations

Rite Aid is a popular pharmacy chain with 24-hour locations across the United States. You can use their store locator tool to find a 24-hour Rite Aid near you.

Jewel-Osco

Jewel Osco pharmacy

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at some locations

Jewel-Osco Pharmacy is a 24-hour pharmacy chain located in the Midwest United States. You can use their store locator tool to find a 24-hour Jewel-Osco near you.

Ralphs

Ralphs pharmacy

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at some locations

Ralphs Pharmacy is a 24 hour pharmacy chain located in the Western United States. You can use their store locator tool to find a 24-hour Ralphs near you.

Pharmacy stores that are open late

Albertsons

Hours: varies by store

Payment methods: Cash, credit, debit, and gift cards

Drive through option: No, walk-in pick up only

Giant Eagle

Hours: varies by store

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at some locations

Hy-Vee

Hours: varies by store

Payment methods: Cash, credit, debit, gift cards and personal checks

Drive through option: Yes, at some locations

Kroger

Hours: varies by store

Payment methods: Cash, credit, debit, and gift cards

Drive through option: No, walk-in pick up only

Publix

Hours: varies by store

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at many locations

Safeway

Hours: varies by store

Payment methods: Cash, credit, debit, and gift cards

Drive through option: Yes, at many locations

Walmart

Hours: varies by store

Payment methods: Cash, credit card, debit, gift cards and personal check

Drive through option: Yes, at some locations

Latuda side effects and how to avoid them

Latuda is the brand name of an FDA-approved drug to treat mental illness. Latuda can cause adverse reactions. The most common side effects tend to be drowsiness and trouble sleeping, to serious movement disorders and worsening mental health. Learn more about the most common Latuda side effects and how to avoid them.

What is Latuda?

Latuda is a medication that belongs to a group of drugs called antipsychotics. It is used for the treatment of bipolar disorder and schizophrenia in adults. It is a central nervous system depressant, which means it reduces activity in parts of the brain. This reduced activity helps to ease the symptoms of both conditions.

Schizophrenia is a mental disorder that causes episodes of psychosis. In these periods you may see or hear things that aren’t really there, have delusional thoughts, and become unusually suspicious. Other symptoms can include difficulties thinking, social withdrawal, and a lack of motivation. Schizophrenia is thought to be caused by a mixture of genetics and events in your life.

Bipolar disorder, previously called manic depression, is another mental disorder. It causes periods of both depression and elevated mood. During the episodes of elevated mood, you may experience psychosis too, as well as excess energy and impulsive behavior. Bipolar disorder is also thought to be caused by both genetics and life events.

Latuda is prescribed to treat:

  • Depressive episodes in adults and children 10 years of age and older with bipolar 1 disorder
  • Depressive episodes in adults with bipolar 1 disorder in combination with mood stabilizer medications like lithium or valproate
  • Schizophrenia in adults and children 13 years of age and older

How does Latuda work?

Latuda contains an active ingredient called lurasidone, a type of atypical antipsychotic drug. When you swallow a Latuda tablet, it breaks down in your digestive tract and the lurasidone it contains is absorbed into your blood. The lurasidone is then transported to your brain in your bloodstream.

Once the lurasidone crosses the blood-brain barrier, it attaches to areas on your brain cells called receptors. These receptors are used to send messages between your brain cells and help to regulate your brain function. Chemicals produced by your brain, called neurotransmitters fit into the receptors, stimulating them and making them send a certain form of signal to the surrounding brain cells. By blocking some of your receptors, lurasidone reduces some areas of brain activity.

Lurasidone blocks receptors that are stimulated by the neurotransmitters dopamine and serotonin. These neurotransmitters help regulate areas of brain activity involved with mood, reward feedback, pleasure, cognition, learning, and memory. By reducing the signals sent by dopamine and serotonin, it is thought that lurasidone helps to normalize brain activity. And this has been shown to lessen the symptoms of schizophrenia and bipolar depression.

Latuda withdrawal

If you stop taking Latuda suddenly, you can experience withdrawal symptoms from the medication, called Latuda discontinuation syndrome. This can cause unpleasant withdrawal-like side effects, including nausea, restlessness, and uncontrolled muscle movements. In some cases, Latuda withdrawal can be severe.

Talk to your doctor if you want to stop taking Latuda. They may decrease your dose slowly to avoid Latuda discontinuation syndrome.

Latuda common side effects

The most common side effects of Latuda include:

  • Sleepiness or drowsiness
  • A runny nose
  • Nausea
  • Vomiting
  • Restlessness and feeling like you need to move (akathisia)
  • Muscle stiffness can slow your movements and make it difficult to move
  • Tremors
  • Problems sleeping (insomnia)
  • Weight gain

Latuda serious side effects

These are rarer, but can include:

  • An increased risk of suicidal thoughts and suicide, particularly in children, adolescents, and young adults (Latuda is not approved for use in pediatric patients with depression – FDA black-box warning)
  • An increased risk of strokes and death in elderly patients who have dementia-related psychosis (Latuda is not approved to treat dementia-related psychosis in older adults – FDA black-box warning)
  • Severe allergic reactions to the medication
  • Worsening episodes of mania or hypomania (manic episodes) in people with bipolar disorder
  • Neuroleptic Malignant Syndrome (NMS) – is a rare but potentially fatal condition caused by a reaction to the medication
  • Uncontrolled body movements (tardive dyskinesia), often in your face and tongue (these movements may not go away after you stop taking Latuda)
  • High blood sugar
  • High blood fats (cholesterol and triglycerides)
  • Abnormally high prolactin levels called hyperprolactinemia
  • A fall in white blood cell counts
  • A fall in blood pressure (orthostatic hypotension)
  • Seizures (convulsions)
  • Trouble swallowing can cause food or liquid to get into your lungs
  • Problems controlling the body temperature that can lead to you overheating and getting dehydrated
  • An increased risk of falls as Latuda can cause dizziness and sleepiness

Your doctor will assess your risk of side effects versus the benefits of taking Latuda. These aren’t all the side effects that Latuda can cause. To find out more, you can read more about Latuda side effects in the leaflet that comes with your medication. Talk to your doctor if you’re concerned about any side effects.

Latuda drug interactions

Latuda should not be taken with medicines called CYP3A4 inhibitors or CYP3A4 inducers, including:

  • Itraconazole, ketoconazole, or voriconazole, taken to treat fungal infections
  • Clarithromycin or rifampin, antibiotics taken to treat a range of bacterial infections
  • Ritonavir, taken to treat an HIV-1 infection
  • Avasimibe, taken to treat high cholesterol
  • Carbamazepine, phenobarbital, phenytoin, and rufinamide, taken for seizures
  • A herbal supplement called St John’s wort
  • Grapefruit juice

Talk to your doctor if you take the following medicines with Latuda:

  • Any other medications you’re taking to treat your bipolar disorder or schizophrenia
  • Any other medications that can affect your serotonin or dopamine levels such as antidepressants
  • Any antibiotics
  • Any medicines that lower your blood pressure

Latuda warnings & precautions

Don’t take Latuda if you:

  • Are allergic to the active ingredient lurasidone
  • Are allergic to any of the other ingredients found in Latuda (listed in the leaflet which comes with the medication)
  • Are under 18 years of age

Talk to your physician before taking Latuda if you:

  • Have diabetes
  • Have decreased kidney or liver function
  • Have heart disease or a family history of having an irregular heartbeat
  • Have a history of blood clots
  • Have a history of epilepsy or seizures
  • Have Parkinson’s disease or dementia
  • Often have suicidal thoughts or behaviors
  • Are pregnant or breastfeeding

How to avoid Latuda side effects

While completely avoiding Latuda side effects may not be possible, there are some things you can do to reduce their severity:

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional. Stick to the same timing for taking your medication and taking it consistently will make a big difference in how well Latuda works for you. Food will help your body absorb Latuda more efficiently. Eat at least 350 calories before taking Latuda.
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Refer to the medication guide for more drug information.

2. Keep cool

Your temperature may fluctuate when taking Latuda, to avoid this keep cool and stay hydrated. Keep a water bottle with you and refill it on a regular basis.

3. Avoid alcohol

Alcohol may worsen any side effects you may experience. Read our blog Latuda and alcohol: can they be used together? for more information.

4. Pay attention to your body

Paying attention to how your body feels when taking Latuda is important, taking particular attention to worsening symptoms or new symptoms. Talk to your doctor straight away for medical advice if you start to experience any side effects of Latuda when taking it.

5. Discuss medical history

Discussing your medical history with your prescribing healthcare provider is important to help them understand how well Latuda will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will also allow them to pick up any drug interactions with Latuda that may increase possible side effects.

Comparing Myrbetriq alternatives: which other medications can I take?

You may be looking for an alternative to Myrbetriq due to adverse effects or maybe it’s not working well enough to treat your symptoms. Symptoms of overactive bladder can negatively affect your life, sometimes for years. It can interrupt your sleep, disrupt your working life, and affect your confidence and wellbeing. The condition can affect men and women of any age. Choosing the right drug treatment for an overactive bladder may make all the difference, so know your treatment options. Let’s take a look at Myrbetriq before we dive into the alternatives.

What is Myrbetriq?

Myrbetriq is an FDA-approved prescription drug manufactured by Astellas Pharma. It is used to treat an overactive bladder (OAB) in adults and neurogenic detrusor overactivity (NDO) in children. OAB is a condition where you feel the need to urinate often and sometimes suddenly. You may feel a combination of:

  1. Need for frequent urination (urinary frequency)
  2. Suddenly needing to urinate (urge incontinence)
  3. Losing control of when you want to urinate (urinary incontinence)

Myrbetriq is available in two extended-release forms and may be prescribed alone or together with the drug solifenacin (Vesicare).

What is an overactive bladder?

An overactive bladder can be triggered by a range of causes. It often involves the muscle tissue in the wall of your bladder. This muscle is relaxed as your bladder fills, then it contracts and squeezes when you urinate. With an overactive bladder, your bladder muscles can contract more often even when your bladder isn’t full. This can cause the OAB symptoms of needing to urinate often, suddenly needing to urinate, not being able to control your urination and leakage. Myrbetriq helps with this as it relaxes your bladder muscles, providing relief from the symptoms of an overactive bladder.

How does Myrbetriq work?

The active ingredient in Myrbetriq is called mirabegron. This drug is classed as a beta-3 adrenergic agonist. Mirabegron relaxes the muscles in the wall of your bladder to reduce the symptoms of an overactive bladder. It does this by attaching itself to areas on the surface of the muscles called receptors (β3-adrenergic receptors). These receptors are stimulated by mirabegron, and they start a process that relaxes the bladder muscles.

Myrbetriq’s common side effects

The most common possible side effects caused by Myrbetriq are:

Unfortunately, in some instances, you could experience more severe side effects such as a severe rise in blood pressure. You may report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

Myrbetriq warnings & precautions

Don’t take Myrbetriq if you:

  • Are allergic to the active ingredient mirabegron
  • Are allergic to any of the other ingredients in Myrbetriq
  • If you have uncontrolled high blood pressure
  • Are under 18 years of age
  • Are pregnant or trying to become pregnant

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Alternatives to Myrbetriq for treatment of overactive bladder

The alternatives shown above are all anticholinergic drugs and work differently from Myrbetriq. Anticholinergic drugs work by relaxing smooth muscle tissue in your bladder. When this smooth muscle tissue contracts, it makes you want to urinate. A natural chemical in your body, called acetylcholine, causes your smooth muscle tissue to contract when it attaches to areas on the surface of the tissue called receptors. But anticholinergic drugs attach to these receptors first, blocking acetylcholine. This helps to stop your smooth muscle tissue from contracting, keeping it relaxed for longer so it can hold more urine.

Work with your healthcare provider to find out which medication is best for you. Always inform your doctor of any medical conditions you have, or medication you are taking including over-the-counter meds, to receive the most appropriate medical advice.

Botched States

Which states have the best and worst plastic surgeons?

Plastic surgery and other cosmetic procedures are increasingly popular in the US, with around 18 million procedures taking place each year, and almost $16.7 billion being spent on them.

And it’s not just limited to one demographic either, with more men going under the knife, and with procedures being popular across many different age ranges.

But which states are the most obsessed with cosmetic surgery? And which are home to the highest-rated, and which should perhaps be avoided?

To find out, NiceRx has analyzed reviews of surgeons from across the country, and taken a look at Google search volume to reveal the most popular procedures in 2022.

Highest rated surgeons

  1. Hawaii – 4.72 / 5

The state that is home to the best plastic surgeons in the country is Hawaii, where the local surgeons average a score of 4.72 out of 5, meaning you may need to hop on a plane if you want to go with the very best.

  1. Nevada – 4.71 / 5

Just 0.01 point behind Hawaii is the state of Nevada, with an average surgeon rating of 4.71 out of 5.00. The majority of surgeons here are based in Las Vegas, with the very highest-rated one being Richards Cosmetic Surgery.

  1. North Carolina – 4.67 / 5

In third place is the state of North Carolina with an average rating of 4.67 out of 5.00.

However, North Carolina has a greater number of surgeons to choose from than Hawaii and Nevada, with 150, compared to just 23 and 43 respectively.

Lowest rated surgeons

  1. North Dakota – 3.95 / 5

The only state where the local surgeons had an average rating of lower than 4.00 is North Dakota, with an average of 3.95. North Dakota is also amongst the states with the fewest surgeons, with just 27.

  1. Alaska – 4.07 / 5

The state with the second-lowest average rating is Alaska, at 4.07. There are even fewer options for those looking to go under the knife here, with just ten surgeons listed in the state.

  1. New Mexico – 4.22 / 5

Completing the three lowest-rated states for plastic surgeons is New Mexico, with an average rating of 4.22 out of 5.00. Despite being the fifth-largest state in the country, New Mexico has just 14 listed plastic surgeons.

Most obsessed

  1. New York – 17,688 cosmetic surgery searches per 100,000 people

When we turn to Google search volume, New Yorkers are those who spend the most time researching plastic surgery. Looking at searches for 100 different procedures, those in the Empire State made 17,688 searches per 100,000 people, more than in any other state.

  1. Washington, D.C. – 17,246 cosmetic surgery searches per 100,000 people

In second place is Washington, D.C., with 17,246 plastic surgery searches per 100,000 people, slightly fewer than in New York, but considerably more than the next state, California.

  1. California – 10,751 cosmetic surgery searches per 100,000 people

As the home of Hollywood, it’s perhaps not surprising to see that Californians are partial to a bit of cosmetic surgery, placing in third place here with 10,751 searches per 100,000 people.

Most popular type

  1. Laser Hair Removal – 4,998,000 annual searches

In terms of the most popular cosmetic procedures nationwide, the most searched by far is laser hair removal, with just below five million searches in the US in the last year. Laser hair removal promises a stubble-free life by using a laser to permanently remove unwanted body hair.

  1. Botox – 2,0220,000 annual searches

The second most popular form of cosmetic procedure in the US is botulinum toxin, better known as Botox, with just over two million searches in the last year. Botox relaxes the muscles in the face to help smooth out lines and wrinkles, although the effects only last for around three to four months.

  1. Liposuction – 1,676,000 annual searches

The top three most popular cosmetic procedures are completed by liposuction, with 1.7 million annual searches. Liposuction is a surgical procedure that involves using a suction technique to remove fat from certain areas of the body, such as the abdomen, hips, thighs, and buttocks.

Methodology

States with the highest-rated surgeons

All information is sourced from Top Plastic Surgeon Reviews which aggregates surgeon reviews from four sources:  Vitals, Healthgrades, Realself, and Google. To calculate an average score for each state, we took the grand total score of all surgeons within each state, dividing this by the total number of reviews for each state.

Note that these figures only relate to surgeons listed on these sites and states with no information were removed from this section.

Most plastic surgery obsessed states

We built a list of 100 different types of cosmetic surgery and used Google Ads Keyword Planner to find the total number of searches made for each of these between April 2021 and March 2022. This figure was then calculated per 100,000 people, using figures from the 2020 U.S. Census.

Most popular cosmetic surgery procedures

Using the same methodology and list of procedures as the above section, we found which procedures received the highest number of searches nationwide.

If you are unable to afford your medication, we may be able to assist. NiceRx provides access to FDA-approved brand-name medications, including Januvia, Janumet, Aubagio, Ozempic, and Trelegy Ellipta.

Xarelto side effects and how to avoid them

Xarelto is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to stop blood clots from forming. A blood clot is formed when some of your blood thickens and forms a gel-like plug in your body. It can block the flow of your blood, and in some cases lead to life-threatening conditions. Xarelto can cause adverse reactions like any other drug. Learn more about Xarelto’s side effects and how to avoid them.

What is Xarelto?

Xarelto is a brand name FDA-approved prescription blood thinner (anticoagulant) medication used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). It is used to reduce the risk of DVT and PE recurring. Xarelto belongs to a class of medications called Factor Xa inhibitors which reduce the chance of blood clots happening and also reduce the risk of coronary heart disease and peripheral artery disease.

It’s prescribed specifically to:

  • Reduce the risk of stroke and blood clots forming in people who have a condition called nonvalvular atrial fibrillation
  • Reduce the chances of a blood clot forming and causing deep vein thrombosis or a pulmonary embolism
  • Reduce the chances of a blood clot forming again in people who are at risk of blood clots after having been treated for them for at least six months
  • Reduce the chances of a blood clot forming in people who have had knee replacement surgery and hip replacement surgery
  • Reduce the risk of serious heart problems, heart attacks, or strokes in people with coronary artery disease
  • Reduce the risk of serious heart problems, heart attacks, or strokes in people with peripheral artery disease

You shouldn’t take Xarelto if you have an artificial heart valve.

How does Xarelto make you feel?

Xarelto will cause common side effects such as muscle pain, stomach pain, diarrhea, and feeling tired. Xarelto may also cause less common but more serious side effects such as low mood, anxiety, and depression. Speak to your doctor if you experience any of these side effects.

What doses of Xarelto are available?

Xarelto comes as a tablet that you swallow. Your dose, and how often you take your Xarelto, will be decided upon by the doctor who prescribes it to you. Xarelto is available in different oral tablet strengths:

  • Xarelto 2.5 mg tablets
  • Xarelto 10 mg tablets
  • Xarelto 15 mg tablets
  • Xarelto 20 mg tablets

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition. There is a higher risk of blood clots if Xarelto is stopped too soon. If you miss a dose, take it as soon as you remember. However, if it is near the time of your next dose, skip the missed dose. For additional safety information, read the full prescribing information and medication guide.

Xarelto active ingredients

The active ingredient in Xarelto is called rivaroxaban. It’s an anticoagulant drug, also called a blood thinner, that reduces the likelihood of clots forming in your blood.

When your blood clots, it goes through a chemical process that turns from a liquid to a thick gel. This chemical process is complex and has a number of steps that happen in sequence. Rivaroxaban works by interrupting one of these steps.

When you take Xarelto, rivaroxaban is absorbed into your blood. It attaches itself to and blocks an enzyme in your blood, called Factor Xa. This enzyme controls a step in the clotting process, and by blocking it, rivaroxaban makes it less likely your blood will clot.

Xarelto side effects

The most common side effects of Xarelto are:

  • Nosebleeds
  • Indigestion
  • Muscle pain
  • Tiredness
  • Stomach pain or discomfort
  • Diarrhea

In rare instances, Xarelto can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • An increased risk of serious bleeding that won’t stop, like a hemorrhage (bleeding from a ruptured blood vessel)
  • An increased risk of spinal or epidural hematoma (bleeding and blood clots in your spine) in patients who take Xarelto and who receive a spinal puncture or local anesthetic injection around their spine – this could result in paralysis
  • Spinal blood clot, symptoms include back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control
  • Vomiting blood that looks like coffee grounds
  • Tarry stools

These are not all the possible side effects of Xarelto. For more information, ask your doctor or healthcare professional about other potential side effects or consult the medication guide.

Does Xarelto cause fatigue?

Feeling tired is a side effect of taking Xarelto but not a common one. Fatigue affects just over 1% of people taking Xarelto for DVT.

Does Xarelto cause liver problems?

Xarelto can cause liver damage. This is more common in males over the age of 60 who have been taking Xarelto for over 6 months. Your doctor will carry out liver function tests if you are taking Xarelto long-term.

Does Xarelto cause hair loss?

Hair loss is not a side effect of taking Xarelto. Speak with your doctor for medical advice if you have concerns about hair loss while taking Xarelto.

Does Xarelto cause weight gain?

Weight gain is not a side effect of Taking Xarelto. Speak with your doctor for medical advice if you have concerns about weight gain while taking Xarelto.

Does Xarelto cause kidney problems?

Xarelto may cause a condition known as anticoagulant-related nephropathy, a type of acute kidney injury (AKI) caused by excessive anticoagulation.

Does Xarelto cause blood in your urine?

Xarelto may cause blood in your urine. Your urine may look brown, red, or pink in color.

Does Xarelto cause back pain?

Muscle pain, especially in the lower back is a common side effect of taking Xarelto.

Does Xarelto cause uncontrolled bleeding?

Most people who report bleeding as a side effect of Xarelto will report mild bleeding. Symptoms of mild bleeding may include bruising. Severe internal bleeding that can be fatal can also occur when taking Xarelto. Speak to your doctor if you have symptoms of bleeding.

Does Xarelto cause itching?

Itching is a side effect of Xarelto but not a common one. Itching affects around 2% of people taking Xarelto.

Does Xarelto cause skin rashes?

Xarelto can cause mild or more serious life-threatening allergic reactions. Common symptoms of an allergic reaction include skin rash.

What are the side effects of Xarelto 20 mg?

You will be more likely to experience side effects at higher doses of Xarelto. These will include back pain, bloody stool, nosebleeds, red or brown urine, headaches, fainting, stomach pain, loss of appetite, and yellowing of your eyes or skin.

What are the bad side effects of Xarelto?

Bad side effects of Xarelto include severe allergic reactions, spinal bleeding or rupture, and severe life-threatening internal bleeding. Speak to your doctor for medical advice about any concerns you may have about taking this medication.

What are the long-term side effects of Xarelto?

Long-term side effects of Xarelto includes liver and kidney problems, serious or life-threatening bleeding, a risk of the build-up of blood around the brain or spine after treatment with spinal injections, and changes in mood, anxiety, or depression.

What are the side effects after stopping Xarelto?

The main side effect after stopping Xarelto, especially if you stop Xarelto too early is the risk of developing blood clots. Talk to your doctor if you are considering stopping Xarelto treatment.

How long do Xarelto side effects last?

Some of the side effects of Xarelto may go in a couple of days to a few weeks from when you first started taking it. Xarelto has a half-life of 5 to 9 hours (the time it takes for half of this medication to leave your body) and takes around 24 hours to completely leave your system.

What are the side effects of Xarelto in the elderly?

Side effects of Xarelto in the elderly are the same as they are for younger patients but may be more common and potentially more severe. Speak to a healthcare professional if you are elderly and have been prescribed Xarelto.

RELATED: Side effects of Xarelto in the elderly

How to avoid Xarelto side effects

While completely avoiding Xarelto side effects may not be possible, there are some things you can do to reduce their severity:

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional. It is typically taken once a day, at the same time each day. Xarelto can be taken with or without food. Sticking to this timing and taking your medication consistently will make a big difference in how well Xarelto works for you.

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Refer to the medication guide for more drug information.

2. Store Xarelto correctly

Xarelto should be stored at room temperature in a dry place in its original container. Knowing how to properly store your medication is important to make sure it remains as effective as possible. Taking expired or improperly stored medication could result in the medication not working properly and may even cause unwanted side effects.

3. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Xarelto will work for you. Give them a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Xarelto that may increase possible side effects.

4. Pay attention to your body

Paying attention to how your body feels when taking Xarelto is important, taking particular attention to bleeding. Try to avoid sports or activities that may cause injury to you. Talk to your doctor straight away if you start to experience any side effects of Xarelto when taking it. Always seek medical advice if you are concerned about your medication.

Xarelto drug interactions

Xarelto can interact with other medications, including:

  • Any other anticoagulant medications, such as clopidogrel
  • Aspirin or aspirin-containing products
  • Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen
  • Any other medications or supplements that can increase your risk of bleeding, including any medications that contain warfarin, enoxaparin, or heparin
  • Any selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants
  • Any medications taken to treat fungal infections, particularly ketoconazole
  • Any antibiotics taken to treat a bacterial infection, particularly erythromycin or rifampicin
  • Any HIV/AIDS medications, particularly ritonavir
  • Any medications taken to treat seizures, particularly phenytoin or carbamazepine
  • A herbal supplement called St John’s Wort

Xarelto contraindications

You should not take Xarelto if you:

  • Are allergic to rivaroxaban or any other ingredients in the medication
  • Are pregnant or planning to become pregnant
  • Are breastfeeding or planning to breastfeed – Xarelto may pass into breast milk
  • Have had a recent spinal puncture or epidural catheter placement
  • Have an active internal bleeding disorder
  • Have a history of spinal surgery

Talk to your doctor before taking Xarelto if you:

  • Have or have had bleeding problems
  • Have liver disease
  • Have antiphospholipid syndrome
  • Have kidney disease or kidney problems
  • Are scheduled to have surgery
  • Are 65 years of age or older
  • Are taking any medications that could increase your risk of bleeding, including any medications that contain warfarin or heparin
  • Are taking any SSRI or SNRI antidepressants
  • Are taking any medications

Be sure to seek medical attention if you are concerned about any side effects you are experiencing.

What foods should I avoid when taking Xarelto?

You may need to avoid grapefruit and grapefruit juice as they may increase the level of Xarelto in your body.

Can you drink alcohol with Xarelto?

Moderate alcohol consumption is safe with Xarelto. You are advised however not to drink excessively as this could increase your risk of side effects.

RELATED: Xarelto and alcohol: can they be used together?

How much does Eliquis cost with Medicare?

In 2022, the manufacturer’s (Bristol-Myers Squibb) website listed the price of Eliquis as $522 for a 30-day supply without insurance.  Patients who have prescription insurance through Medicare pay $37 on average for Eliquis, according to the manufacturer of Eliquis. The manufacturer also states that some Medicare patients with Part D coverage may pay as little as $10 per month for Eliquis through the use of a Medicare Part D prescription drug plan or a Medicare Advantage Prescription Drug (MAPD) plan that includes prescription drug coverage.

The amount an individual pays for Eliquis depends on various factors such as:

  • the type of Medicare coverage
  • the formulary tier (list of covered drugs)
  • whether the individual has reached their annual deductible amount
  • coinsurance or copayments

What is Eliquis?

Eliquis (apixaban) is an anticoagulant (blood thinner) medication used to prevent strokes and blood clots in people with atrial fibrillation (afib, a heart rhythm disorder). Eliquis is also used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), two types of blood clots that can occur in the legs or lungs.

Eliquis works by inhibiting a protein called factor Xa. Factor Xa is involved in the clotting process. By inhibiting factor Xa, Eliquis decreases the formation of clots.

What about generic Eliquis?

There is no generic version of Eliquis currently available. The earliest possible date that a generic version could become available is December 2023, when the patent for Eliquis expires.

What’s the cheapest way to get Eliquis?

There are a few ways to save on the cost of your Eliquis prescription. One way is to use a prescription discount card, such as the ones offered by manufacturer assistance programs or independent organizations. Manufacturer assistance programs provide discounts for eligible individuals. Other ways to save include using a mail-order pharmacy or looking for an Eliquis coupon or other special offers.

Some insurance plans may help to reduce the cost of Eliquis but may have higher copays, deductibles or higher premium fees. You may be able to save money by switching to a Medicare Advantage Prescription Drug (MAPD) plan that includes prescription drug coverage, or by enrolling in a Medicare Part D prescription drug plan.

You can also ask your healthcare provider about the possibility of getting a sample pack of Eliquis from the manufacturer. This could help you decide if Eliquis is the right medication for you before you commit to paying for a full month’s supply.

Eliquis costs are high, but there are ways to reduce the cost. Talk to your healthcare provider about your options and compare costs between different pharmacies to find the best price.

Does Medicare cover Eliquis?

Medicare Part A (hospital insurance) does not cover Eliquis because it is not a hospital-administered medication.

Medicare Part B (medical insurance) does not cover Eliquis because it is considered an outpatient medication.

However, Medicare Part D plans (prescription drug plans) and Medicare Advantage plans with prescription drug coverage (MAPDs) may cover Eliquis.

If an individual has Original Medicare and they would like coverage for Eliquis, they will need to enroll in a stand-alone Part D plan or a Medicare Advantage Prescription Drug (MAPD) plan that includes prescription drug coverage.

Fortunately, there are Eliquis coupons available for Medicare consumers and people without health insurance to help significantly lower the cost of this medication.

Get your Eliquis medication for only $49 per month

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Medicare Part D plans and Eliquis coverage

Medicare Part D plans (PDPs) and Medicare Advantage Prescription Drug (MAPD) plans are required to cover all FDA-approved drugs. Since Eliquis is an FDA-approved drug, it must be covered by all PDPs and MAPDs that offer prescription drug coverage.

However, each plan has its own rules about how much it will cover for each type of drug in its formulary (list of covered drugs). Some plans may place Eliquis on a higher tier of their formulary (list of covered drugs), which means that patients will have to pay a higher coinsurance or copayment for the medication. Other plans may exempt Eliquis from the annual deductible amount.

If an individual has a Medicare Part D prescription drug plan or a Medicare Advantage Prescription Drug (MAPD) plan, they will likely pay a monthly premium, an annual deductible, and coinsurance or copayments for their Eliquis medication. The average monthly premium for a Medicare Part D prescription drug plan in 2022 is $33, according to CMS.  No Medicare drug plan may have a deductible of more than $480 in 2022 which means that you are responsible for the first $480 of out of pocket costs for your prescription drugs before your coverage commences.

Medicare Part D prescription drugs are the most common way of obtaining coverage from Medicare for prescription drugs such as Eliquis. If an individual has Medicare Part D, also called prescription drug coverage, they may be able to get Eliquis at a lower cost. Part D plans have a list of covered drugs (formulary drug list) and use tiered formularies. The cost of Eliquis depends on which tier the drug is placed in.

There are four tiers:

  • Preferred or Generic (lower-cost drugs)
  • Non-preferred or Brand-name (higher-cost drugs)
  • Specialty (very high-cost drugs)
  • Not Covered Drugs

If an individual has Medicare Part B, they may be able to get help with the costs of Eliquis through the Eliquis Access Program. The Eliquis Access Program offers free or low-cost medications to eligible patients. To see if you qualify for this program, visit the manufacturer’s website or speak with your doctor.

Eliquis and Medicare Advantage

Medicare Advantage plans (Medicare Part C) are an alternative to the Original Medicare. These plans are offered by private insurance companies and must cover all the same benefits as Original Medicare Some Medicare Advantage plans also offer prescription drug coverage. If an individual has a Medicare Advantage plan that includes prescription drug coverage, they may be able to get Eliquis at a lower cost. Like with Part D plans, the cost of Eliquis depends on which tier the drug is placed in and whether the individual has met their deductible. To see what your specific plan covers, you can view your plan’s formulary or contact your plan’s customer service department.

You can also compare Medicare Advantage plans that include prescription drug coverage on the Medicare website. When you compare plans, be sure to look at the total cost of the plan, not just the monthly premium. You should also consider whether the plan covers your preferred pharmacies and doctors.

Can Medigap plans help me save money on Eliquis?

No, Medigap plans cannot be used to help pay for prescription drugs. Medigap plans are supplemental insurance plans that can help cover some of the costs that Original Medicare does not cover, such as copayments, coinsurance, and deductibles. While Medigap plans cannot help with the cost of Eliquis specifically, they can help with some of the other costs associated with Medicare.

How much does Eliquis cost with Medicare?

Medicare patients with Part D coverage pay on average $37 for Eliquis while some Medicare Part D patients may as low as $10 for Eliquis, according to the manufacturer of Eliquis.

Eliquis assistance for Medicare patients

If you have Medicare and need help paying for Eliquis, there are a few options that may be able to help.

  • Eliquis coupons and Eliquis copay cards may be available to eligible individuals from the manufacturer.
  • The Eliquis Access Program offers free or low-cost medications to eligible patients. To see if you qualify for this program, visit the manufacturer’s website or speak with your doctor.
  • Patient Assistance Programs (PAPs) are programs offered by pharmaceutical companies to help people who cannot afford their medication. Eligible patients may be able to get Eliquis for free or at a reduced cost.
  • You may also be eligible for Extra Help. Extra Help is a program that helps people with limited income and resources pay for their prescription drugs. To see if you qualify for Extra Help, visit the Social Security Administration website or call 1-800-772-1213.
  • If you cannot afford your medication, your doctor may be able to give you samples of Eliquis to try. Doctors sometimes receive free samples from pharmaceutical companies. These samples can then be given to patients who cannot afford their medication.
  • There are also alternative medications available including Xarelto, Pradaxa and Savaysa.

 

Humira side effects and how to avoid them

Humira is a biologic medication used to treat autoimmune diseases like rheumatoid arthritis and similar inflammatory diseases like Crohn’s disease. Humira can cause adverse reactions ranging from joint pain to reactivation of hepatitis B. Learn more about Humira’s side effects and how to avoid them.

What is Humira?

Humira (adalimumab) is an injectable prescription drug manufactured by AbbVie. It is FDA-approved to treat autoimmune conditions like rheumatoid arthritis, Crohn’s disease, and psoriasis. This medicine belongs to a class of biologic medications known as tumor necrosis factor (TNF) blockers.

TNF is a protein in the body that can cause inflammation. Normally excess TNF in the blood is naturally controlled. But in people with certain immune conditions, TNF levels are higher, leading to excessive inflammation. Inflammation is harmful to your body when it is out of control as it can cause severe pain and swelling.

Humira causes a reaction in your immune system by binding to TNF and preventing it from triggering the inflammatory reaction. Other TNF blockers that are FDA-approved include:

What is Humira used for?

Humira can be used used to treat:

Humira can be used alone or with methotrexate.

How to take Humira?

You take your dose of Humira by injecting it under your skin as a subcutaneous injection, using either a prefilled syringe or an injectable pen. Don’t try to inject Humira yourself until you’ve been shown how to inject it and you’re confident you understand how to do it properly.

If you are being treated with Humira and you need to travel, it can be stored at room temperature, up to a maximum of 77°F (25°C), for up to 14 days (while protected from light).

Side effects of Humira

Humira is an effective treatment but like all prescription medications, it can cause side effects. Read the medication guide that comes with Humira and consult a healthcare professional for further medical advice.

People may experience the following common side effects of Humira:

  • Injection site reactions such as bruising or itching
  • Joint pain
  • Weight loss
  • Shortness of breath
  • Upper respiratory infections e.g. sinus pain
  • Coughing
  • Diarrhea
  • Fatigue
  • Stomach upset

Examples of the most serious side effects relating to taking Humira include:

  • Liver damage/liver problems – yellowing of the eyes or skin, right-sided abdominal pain, vomiting, and fatigue
  • Nervous system problems such as multiple sclerosis or Guillain-Barre syndrome with symptoms such as numbness and tingling in your hands and feet, vision changes, and dizziness
  • Allergic reactions ranging from having trouble breathing to hives
  • Immune system changes such as lupus-like syndrome to symptoms such as joint pain, skin rash, chest pain, or shortness of breath
  • Increased risks for infections – these include sepsis, tuberculosis, and other opportunistic infections due to viral, bacterial, or fungal infections
  • Increased risk of cancer, particularly lymphoma (cancers of the white blood cells) and skin cancer
  • Reactivation of a hepatitis B infection in people who carry the hepatitis B virus
  • Heart failure or worsening heart failure

How to avoid Humira side effects?

1. Discuss medical history and medications

Due to the possibility of serious side effects, you should discuss with your doctor if you:

  • Have previously had cancer
  • Have an infection, or a condition that makes it easier for you to get infections
  • Have infections that keep coming back
  • Have had mild heart failure, or another serious heart condition
  • Have a demyelinating disease, like multiple sclerosis
  • Have hepatitis B virus (HBV)
  • Are about to have surgery or a dental procedure
  • Are about to have a vaccination
  • Are over 65, as Humira can make it more likely you’ll get infections
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

You should always inform your pharmacist or healthcare professional about prescription medications and other medications you take including over-the-counter meds and supplements to prevent any drug interactions.

2. Rotate your injection site

The importance of rotating insulin injection sites is to maintain effective drug absorption. Small fatty lumps or hard lumps could develop in areas that are continuously used as injection sites. These can interfere with drug absorption and also cause discomfort. Rotate between injecting sites every two weeks, for example, left thigh, right thigh, right side of the abdomen, and left side of the abdomen.

3. Avoid infections

Humira makes patients more prone to infections. Wash your hands on a regular basis, avoid people with infections and wear a mask in public places.

4. No live vaccines

Live vaccines such as yellow fever, BCG, cholera, typhoid, and varicella should never be given to Humira patients. There is also an increase in the risk of serious infections when Humira is taken with abatacept (Orencia) and anakinra (Kineret).

5. Talk to your doctor about citrate-free Humira

If the pain of injecting Humira is too much for you there is a citrate-free Humira version that will cause less pain.

Your healthcare provider will assess the benefits of using Humira against your risk of side effects and provide you with full Humira drug information. Patients are encouraged to report negative side effects or adverse reactions to Humira to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

How to use an inhaler

Do you use inhalers for your asthma treatment or for chronic obstructive pulmonary disease (COPD)? Are you are using them correctly? Incorrect use makes inhalers less effective in controlling your asthma symptoms because the medication may not even be getting into the lungs. If you have asthma, it is important to make sure that your asthma inhaler technique is correct. It’s a good idea to bring your inhaler to your medical appointments. That way your health care provider can make sure you are using it correctly. Read on for a quick guide on how to use an inhaler.

Types of inhalers

Inhalers can deliver medicines to open the airway and let more air move in and out of your lungs. This means air can flow freely into your lungs to prevent asthma attacks, relieve symptoms during an asthma attack, or do both. There are two main types of inhaler devices.

Metered-dose inhalers (MDI)

Advair HFA, Alvesco, Atrovent HFA, Dulera, Flovent HFA, ProAir HFA, Proventil HFA, QVAR, Symbicort, Trelegy Ellipta, Anoro Ellipta, Spiriva Handihaler and Ventolin HFA, are examples of products available as an MDI.

This is the most commonly used type of inhaler in use since the 1950s. The inhaler can be described as boot-shaped with the mouthpiece sticking out at the bottom into which a pressurized canister is inserted. The aerosol canister contains corticosteroid medication.

A measured amount of medicine is delivered to your lungs by inserting the mouthpiece into your mouth and pushing down on the canister while inhaling. A counter on the inhaler shows you how many doses are remaining in the canister.

The most difficult but essential part of using an inhaler is to coordinate your inhalation with the release of medicine from your inhaler to ensure that the drug reaches your lungs.

To reduce the possibility that the medicine stays in your mouth, a holding chamber called a spacer can be attached to your MDI. Spacer devices make it easier to get the medicine into your lungs by holding the release of medicine. It creates more time for you to inhale slowly, deeply, and at your own pace to get the full dose into your lungs. Some MDIs, called breath-actuated inhalers, automatically release a puff of medicine when you inhale.

Be aware of the type of inhaler your doctor prescribes to you and double-check that you are using it correctly by demonstrating your technique. If anything is unclear on how to use your inhaler ask your doctor, pharmacist, or healthcare provider.

Types of inhalers

Steps to using an MDI (inhaler without a spacer)

Get the inhaler ready for use

  • Take the cap off
  • Look inside the mouthpiece and make sure there is nothing in it
  • Prime the inhaler. This simply means spraying it into the air. You need to do this when you use an inhaler for the first time, or if you haven’t used it for 2 weeks or more
  • Before each use shake the inhaler 10 to 15 times
  • Breathe out all the way

Breathe in slowly

  • Hold the inhaler upright with the mouthpiece down. Place your lips around the mouthpiece so that you form a tight seal around it and take a slow deep breath
  • As you start to slowly breathe in through your mouth press down on the inhaler one time
  • Keep breathing in slowly, as deeply as you can

Hold your breath

  • Take the inhaler out of your mouth. If you can, hold your breath as you slowly count to 10. This lets the medicine reach deep into your lungs
  • Pucker your lips and breathe out slowly through your mouth
  • If you are using inhaled, quick-relief medicine like Ventolin, wait about 1 minute before you take your second puff. You do not need to wait a minute for your next puff for other medicines such as steroids
  • Replace the cap on the mouthpiece and make sure it is firmly closed
  • After using your inhaler, rinse your mouth with water, gargle, and spit this helps reduce side effects from your medicine

Clean your inhaler

  • Remove the metal canister from the L-shaped plastic mouthpiece
  • Rinse only the mouthpiece and cap in warm water
  • Air-dry overnight
  • In the morning, put the canister back inside. Put the cap on
  • Do not rinse any other parts

Dry-powder inhaler

Accuhaler, Turbuhaler, HandiHaler, Ellipta, and Genuair are examples of dry powder inhalers.

This type of device doesn’t use a chemical propellant like an MDI to deliver medicine into your lungs. Instead, it contains a powdered formula that you draw into your lungs with a deep, fast inhalation.

How to use an inhaler

Steps to using a dry powder inhaler

  • Remove the cap
  • For a single-use device, load a capsule. Make sure you do not tilt the inhaler while you are loading the dose
  • Breathe out slowly (not into the mouthpiece)
  • Put the mouthpiece between your front teeth and close your lips around it
  • Breathe in through your mouth deeply for 2-3 seconds
  • Remove the inhaler. Hold your breath for as long as you can
  • Breathe out slowly
  • Make sure you close the inhaler after you use it

It is a matter of trial and error to find the best inhaler for you. It is a balance between the correct medication and the type of inhaler that suits your needs and your ability to use the inhaler correctly.

Your asthma specialist or other health care provider will provide you with training to use the device you choose correctly.

Can I try a nebulizer?

A nebulizer may be a better option if you have severe asthma. It is not technically an inhaler but is another option provided by your healthcare professional. Nebulizers let you take your medicine while breathing normally, but they are more time-consuming to set up and use than inhalers. This machine turns liquid medicine into a fine mist that you inhale through a mouthpiece, a mask that fits over your nose and mouth, or into your mouth alone.

When do I replace my inhaler?

On the canister of your MDI or on the side of your dry powder inhaler will be a counter. Keep an eye on the counter and replace the inhaler before you run out of medicine.

How do I store my inhaler?

Store your inhaler at room temperature. It may not work well if it is too cold. The medicine in the canister is under pressure. So make sure you do not get it too hot or puncture it.

Wegovy side effects and how to avoid them

Wegovy can cause adverse reactions. The more common side effects tend to be nausea and diarrhea to more serious side effects such as a risk of hypoglycemia. Learn more about Wegovy side effects here and how to avoid them.

What is Wegovy?

Wegovy is an FDA (U.S. Food and Drug Administration) approved prescription drug manufactured by Novo Nordisk, Inc. Wegovy is a higher-dose, 2.4 mg version of the diabetes drug Ozempic (semaglutide).

It is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated in combination with a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with a body mass index (BMI):

  • 30 kg/m2 or greater (obesity)
  • 27 kg/m2 or greater (overweight) who also have at least one weight-related medical condition such as type 2 diabetes, high blood pressure, or high cholesterol

GLP-1 is a physiological regulator of appetite and caloric intake, by blocking this hormone semaglutide affects appetite leading to lower body weight through decreased calorie intake.

Wegovy should not be used in combination with other semaglutide containing products or any other GLP-1 receptor agonist. The safety and efficacy of use with other products for weight loss have not been established. Also, Wegovy has not been studied in patients with a history of pancreatitis.

Semaglutide causes thyroid C-cell tumors in rodents at clinically relevant levels. It is not known if Wegovy causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as the human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined.

Wegovy is not recommended in patients with a personal or family history of MTC or in patients with multiple endocrine neoplasia syndrome type 2. It is important to know the potential risk of MTC and symptoms of thyroid tumors.

What doses of Wegovy are available?

Wegovy is available in prefilled injection form, in the following doses: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, or 2.4 mg.

The semaglutide injection is injected under the skin (subcutaneous) usually once every 7 days. The injection sites are the thigh, abdomen, or upper arm. The dose you receive is based on your medical condition and your response to treatment. If you miss your weekly dose of Wegovy and there are less than 3 days until your next dose, do not take the missed dose. The Wegovy injection can be stored at room temperature or in the refrigerator.

Start at 0.25 mg once weekly for 4 weeks. Increasing the dose 4 weekly until a dose of 2.4 mg is reached. The maintenance dose of Wegovy is 2.4 mg once weekly.

See the full prescribing information for the complete boxed warning. You are recommended to read the medication guide and advised to always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

RELATED:  Wegovy dosage

Wegovy active ingredients

Wegovy contains semaglutide as the active ingredient.

Wegovy common side effects

The most common side effects of Wegovy in clinical trials compared to placebo include:

  • Nausea
  • Diarrhea
  • Bloating
  • Indigestion
  • Constipation
  • Abdominal pain
  • Flatulence, gastroenteritis, and gastroesophageal reflux disease (heartburn)

How to avoid the common side effects of Wegovy

  • Eat bland, low-fat foods like crackers, toast, and rice
  • Eat foods that contain water, like soups and gelatin
  • Avoid lying down after you eat
  • Eat slowly
  • Go outdoors for fresh air

If after trying these tips, the side effects are still bothersome speak to your healthcare provider for medical advice.

Wegovy serious side effects

In rare instances, Wegovy can cause more serious side effects. These can include:

  • Risk of hypoglycemia (low blood sugar) in patients with type 2 diabetes, thyroid C-cell tumors/ thyroid cancer
  • Acute pancreatitis (inflammation of the pancreas)
  • Acute gallbladder disease
  • Acute kidney injury or renal impairment – monitor renal function when initiating or escalating doses if severe adverse gastrointestinal reactions occur
  • Allergic reactions
  • Diabetic retinopathy complications in patients with Type 2 Diabetes
  • Increase in heart rate
  • Suicidal thoughts

Your doctor will assess the benefits of using Wegovy against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions to Wegovy to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You should always inform your pharmacist or healthcare professional about other medications you take including over-the-counter meds and supplements to prevent any drug interactions. If you are pregnant, planning to become pregnant or breastfeeding inform your doctor immediately.

Generic vs brand name drugs

There are often a lot of questions surrounding generic and brand-name medication. Are generics really as effective? Which one is better? When is one preferable over the other? There are only two main differences between generic and brand-name drugs: different inactive ingredients, or preservatives and cost. Let’s take a deeper look into the differences between generic medications and brand-name versions of prescription drugs.

What is a generic drug?

A generic drug is a medicine that contains the same active ingredient as the branded medicine and is a chemical copy of the branded drug. e.g. the brand name product Glucophage is used to treat diabetes but its generic name is metformin.

Generic drugs can look quite different from their brand-name counterparts, despite having the same active ingredient, strength, form, uses, route of administration, and labeling. United States trademark laws do not allow generic drugs to look exactly the same as the equivalent brand-name drugs.

Generic drugs are versions of brand-name drugs and may offer cost-saving treatment options to patients. Pharmaceutical companies begin with exclusivity protection for many years to allow them to profit from their research and development of the drug. New drugs, incur significant costs in research, development, and clinical trials. After patent expiry, generic drug manufacturers can enter and gain market share.

Applications from generic drug companies submitted to the U.S. Food and Drug Administration (FDA) for approval must show that:

  • The generic drug is “pharmaceutically equivalent” to the brand
  • The manufacturer is capable of making the drug correctly
  • The manufacturer is capable of making the drug consistently
  • The “active ingredient” is the same as that of the brand
  • The right amount of the active ingredient gets to the place in the body where it has an effect
  • The “inactive” ingredients of the drug are safe i.e. fillers, binders, and flavors
  • The drug does not break down over time
  • The container in which the drug will be shipped and sold is appropriate
  • The label is the same as the brand-name drug’s label
  • Relevant patents or legal exclusivities are expired

What is a brand-name drug?

Brand medications are the first of their kind, the creators, the inventors. The pharmaceutical company that discovers this drug gets to “brand the name” of the drug. Pharmaceutical companies invest a lot of time and money to become the first to develop a drug. The process involves drug discovery research and development, manufacturing costs, and then finally marketing of the product.

The FDA approval process involves rigorous evaluation of clinical trial findings, examination of the drug’s purity, stability, strength, and manufacturing processes before approving the medication. Once the drug is granted FDA approval the company can give the medication a brand name and begin marketing. The brand is protected by a patent so other drug manufacturers cannot produce a generic version and duplicate the drug.

The patent gives the drug company an exclusivity period in which they can sell their drug products and get back the money invested during drug development and generate a profit. Like any business, drug companies need to generate a profit to survive.

Your pharmacist can answer any concerns you have about brand or generic medications and other medical advice. You can also visit the FDA website www.fda.gov or call 1-888-INFO-FDA for more information.

FAQs

Do all brand-name drugs have a generic equivalent?

No. Generic drugs usually become available after patents protecting a brand-name medicine expire.

Can I save money by asking my doctor for a generic alternative?

Yes. Lower cost is associated with generic medicines than brand-name drugs because studies and trials don’t have to be repeated to make generic drugs.

Is it always better to choose a generic over a brand-name medication?

No. For drugs with a narrow therapeutic index, it is better to stick with a brand-name drug if your healthcare provider recommends it.

Is my doctor aware of what consumers and health insurance costs are for drugs?

No, not always. Prescribing healthcare professionals can not keep track of drug prices due to the vast number of drugs available although they might be made aware by patients who can’t afford their copays.

Do generic drugs look the same as their brand-name counterparts?

No. Despite having the same active ingredient, quality standards, strength, uses, dosage form, route of administration, side effects and labeling both look quite different from one another.

Do generic drugs save the healthcare system money?

Yes. Generic drugs have lower prices and have saved the US healthcare system $253 billion in 2017 and more than $1 trillion in the past decade. In a recent study, it was found Medicare savings of $1 billion annually could be made if generic prescriptions were consistently provided over brand name ones.

Trulicity side effects and how to avoid them

Trulicity is a diabetes medication used for the treatment of type 2 diabetes mellitus. It is often prescribed with metformin alongside diet and exercise to help manage blood glucose levels. Trulicity isn’t used to treat type 1 diabetes. Just like other drugs, it can cause adverse effects. It’s important to talk to your healthcare professional for medical advice about possible side effects that trouble you or are persistent. Learn more about Trulicity side effects and how to avoid them.

What is Trulicity?

Trulicity is a brand-name drug manufactured by Eli Lilly. It is an FDA (Food and Drug Administration) approved prescription drug for adults who have type 2 diabetes. It helps to:

  • Reduce blood sugar levels when used alongside exercise and dietary changes
  • Reduce the risk of serious heart problems, such as strokes or heart attacks, in people with heart disease or who have risk factors for cardiovascular disease

If you have type 2 diabetes, you may not produce enough insulin, or you may even become resistant to insulin. If this happens, you will absorb less sugar from your blood, resulting in high blood sugar levels.

Trulicity can help you lower your blood glucose. It encourages your pancreas to secrete more insulin and reduces how much sugar is released into your blood. This can help to reduce your diabetes symptoms and the likelihood of developing other serious health conditions if taken alongside changes to your daily life, like increasing exercise and having a healthier diet.

Trulicity active ingredients

Trulicity is classed as a peptide-1 receptor agonist. The active ingredient dulaglutide is absorbed into your digestive system, which it has two effects. It binds with areas on some of your cells called glucagon-like peptide-1 (GLP-1) receptors. This encourages your pancreas to make more insulin, allowing cells in your body to more effectively remove sugar from your blood. At the same time, dulaglutide also reduces how much sugar your pancreas allows to be released into your blood. The combination of these two processes can reduce your blood sugar levels.

How to use Trulicity

Trulicity is usually taken once a week by injecting it under your skin using a prefilled injection pen. Each Trulicity pen holds one single dose of the drug. Use a new pen for each weekly dose. You can inject your dose of Trulicity into your upper arm, abdomen, or thigh. It is important to change the injection site every week. You can inject Trulicity whether you’ve eaten or not.

Trulicity has 4 dose options: 0.75 mg/0.5 mL solution in a single-dose pen, 1.5 mg/0.5 mL solution in a single-dose pen, 3 mg/0.5 mL solution in a single-dose pen and 4.5 mg/0.5 mL solution in a single-dose pen.

If a dose is missed, it can be taken as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose. If less than 3 days remain before the next scheduled dose, skip the missed dose and administer the next dose on the regularly scheduled day.

You may store the opened medicine pen or prefilled syringe in the refrigerator or at room temperature for up to 14 days.

RELATED: Does Trulicity need to be refrigerated?

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Common side effects of Trulicity

Common Trulicity side effects include nausea, vomiting, diarrhea, indigestion, constipation, abdominal pain (stomach pain), and reduced appetite leading to weight loss.

In clinical trials, 8% to 29% of people using Trulicity experienced some nausea during the first 2 to 3 days after they took their first dose. Nausea eased off after the first 2 weeks, but some people experienced nausea with Trulicity beyond their second week of treatment.

The best way to avoid these common side effects is to eat smaller meals and try splitting your 3 daily meals into 4 or smaller ones, stop eating when you feel full and choose foods that are not fatty but are bland such as toast, crackers, or rice.

More serious side effects of Trulicity include:

  • Low blood sugar (hypoglycemia) – your blood sugar falls too low, particularly when used with other medications like insulin or sulfonylurea. You can reduce your risk of low blood sugar levels by doing a few basic things. Sticking to a daily routine of meals, injecting your insulin at set times each day, and measuring your blood glucose using a blood glucose monitor to make sure you don’t inject insulin when your glucose levels are already low. See our blog on how to lower blood sugar fast for more information
  • Severe allergic reactions to the medication
  • Thyroid tumors and a type of thyroid cancer called medullary thyroid carcinoma
  • Inflammation of your pancreas (pancreatitis)
  • Kidney problems, including kidney failure
  • Severe stomach problems
  • Diabetic retinopathy (caused by damaged blood vessels in the eye, which may lead to vision loss)

Your pharmacist or healthcare provider can give you full drug information on Trulicity, including drug interactions with prescription drugs, over-the-counter medicines, and supplements. Before taking Trulicity, speak to your healthcare provider about any medical conditions you may have, including if you are pregnant or breastfeeding.

Generic Symbicort Inhaler approved by FDA for asthma and COPD

On March 15, 2022, the U.S. Food and Drug Administration (FDA) approved the first generic of Symbicort for the treatment of asthma and chronic obstructive pulmonary disease (COPD). This is great news for those who suffer from these conditions, as Generic Symbicort will be a much more affordable option than the brand name version. In this blog post, we will discuss the details of this announcement, as well as what it means for those who suffer from asthma or COPD. Asthma affects 25 million people, and more than 5 million of them are children. COPD affects more than 16 million, according to the National Heart, Lung, and Blood Institute.

Breyna will be the first generic version of Symbicort metered-dose inhaler and will be marketed and sold by Mylan Pharmaceuticals, Inc., a subsidiary of Viatris, in partnership with its drug delivery device partner Kindeva Drug Delivery LP. Mylan intends on launching Breyna in 2022 according to a press release from Viatris. According to Viatris, Breyna is a drug-device combination product, indicated for patients who are suffering from asthma or chronic obstructive pulmonary disease (COPD).

What is Symbicort generic inhaler?

Symbicort generic is a lower-cost version of the brand-name drug Symbicort and is just as effective. Similar to Symbicort, this generic version will contain a combination of an inhaled corticosteroid (budesonide) and a long-acting bronchodilator (formoterol). Symbicort is a combination of two drugs, budesonide and formoterol fumarate dihydrate. The inhaler is approved for 2 strengths: 160/4.5 mcg/actuation and 80/4.5 mcg/actuation. It is used to treat two pulmonary conditions:

  • asthma in people 6 years of age and older
  • maintenance treatment of airflow obstruction and reducing exacerbations for people with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema

Symbicort is a complex mixture of two drugs in a single inhaler. Budesonide is a corticosteroid that works by reducing inflammation in the lungs. Formoterol is a long-acting beta-agonist (LABA) that relaxes and opens air passages in the lungs, making it easier to breathe. It should not be used to treat acute asthma attacks.

What does this approval mean for individuals with asthma and COPD?

The U.S. Food and Drug Administration (FDA) approval of Symbicort generic means that it is just as safe and effective as the brand-name drug. This is great news for those who suffer from asthma or chronic obstructive pulmonary disease (COPD), as Symbicort generic will be a more affordable option for long-term maintenance treatment.

This FDA approval of Generic Symbicort is great news for those who suffer from asthma or COPD, as it will provide a much more affordable option. Inhalers can be very expensive, and the brand name Symbicort inhaler can cost over $300 per month. The generic version will be much cheaper, and will likely be available in late 2022.

When will generic budesonide/formoterol be available?

The manufacturer of Breyna (budesonide and formeterol), Viatris, has indicated that Breyna should be available sometime in 2022. The exact release date for the generic version of Symbicort is unknown at this time.

The manufacturer of Symbicort, AstraZeneca, is involved in litigation with Mylan (Viatris) and depending on the outcome of the lawsuit, the generic release date may be delayed.

How much will generic Symbicort cost once it’s available?

At this time it is not known how much the generic version of Symbicort will cost. However, generic drugs are typically cheaper than brand-name drugs because they don’t have to go through the costly process of research and development.

The upcoming generic competition is great news for sufferers of asthma and COPD as the brand name Symbicort is a very expensive drug that has generated over $3.5 billion in sales for AstraZeneca for the 12 months ending in January 2021.

Are there cheaper alternatives to Symbicort available?

There are several other prescription medication alternatives to Symbicort that are available to treat asthma and COPD. These medications have different strengths, dosages, and indications.

Compare Symbicort alternatives

Drug nameApproved usesSide effectsGeneric available
Advair Diskus (fluticasone/salmeterol)Asthma, COPDHoarseness, nausea, nasopharyngitis
Advair HFA (fluticasone/salmeterol)AsthmaHoarseness, nausea, nasopharyngitis
Asmanex HFA (mometasone)AsthmaHeadache, sinusitis, nasopharyngitis
Breo Ellipta (fluticasone/vilanterol)Asthma, COPDHeadache, oral thrush, nasopharyngitis
Breztri Aerosphere (budesonide/glycopyrrolate/formoterol)COPDBack pain, pneumonia, oral thrush
Dulera (mometasone/formoterol)AsthmaHeadache, sinusitis, nasopharyngitis
Flovent HFA (fluticasone)AsthmaSinusitis, upper respiratory infection, throat irritation
Pulmicort Flexhaler (budesonide)AsthmaNasopharyngitis, nasal congestion, nausea
Qvar Redihaler (beclomethasone)AsthmaNasopharyngitis, sore throat, oral thrush
Singulair (montelukast)Asthma, allergic rhinitisDizziness, stomach pain, headache
Spiriva Respimat (tiotropium)Asthma, COPDDry mouth, upper respiratory infection, sinusitis
Trelegy Ellipta (fluticasone/umeclidinium/vilanterol)Asthma, COPDBronchitis, nasopharyngitis, headache

Other common alternatives to Symbicort include:

It is recommended to obtain medical advice from your healthcare professional about any possible alternatives to Symbicort. Not all of these medications have generic alternatives available.

How much does brand-name Symbicort cost?

For people without insurance coverage for this medication, the estimated retail price for a 30-day supply of Symbicort according to the manufacturer is $303.42 (80/4.5 mcg) and $346.83 (160/4.5 mcg).

The manufacturer states that the average out-of-pocket cost for those with:

  • Commercial insurance coverage is around $33.22 per month
  • Medicare Part D coverage is around $31.03 per month
  • Medicaid coverage is around $.90-$1.82 per month and some states offer even lower co-pays or eliminate the co-pay

Why is Symbicort so expensive?

Symbicort is a brand-name drug with no generic alternatives on the market. Typically, brand-name drugs are more expensive than generic drugs as a single pharmaceutical company has a monopoly over the sale of the medication during the patent protection period.

Symbicort side effects

Common side effects of Symbicort include:

  • Throat irritation
  • Thrush in the throat and mouth
  • Lower respiratory tract infections
  • Inflammation of the inner linings in the sinuses
  • Upper respiratory tract infection

This is not a complete list of all possible side effects while using this medication. Speak with your healthcare provider if you experience any adverse reactions while using this medication.

How do I save money on Symbicort?

There are a few options to consider that could help you save money on Symbicort until the generic version is available:

  1. Patient assistance programs – find out if you are eligible for enrollment into the Symbicort patient assistance program.
  2. Ask your prescribing doctor for free samples of Symbicort – many pharmaceutical companies provide healthcare providers with free medication samples to provide to their patients to help them get started on the medication.
  3. Get medical advice from your healthcare professional and find out if there are any alternative treatment options – there are many Symbicort alternatives available including lower-cost generic alternatives.
  4. Shop around for the lowest price at multiple pharmacies – the price for Symbicort may vary by pharmacy so you should always check pricing at multiple pharmacies to find the lowest possible price for this medication.
  5. Symbicort coupons – check if there is a Symbicort manufacturer coupon that can help you save money when purchasing this medication.
  6. Get help from Medicaid – find out if you are eligible for a state Medicaid plan that may cover some or all of the cost of Symbicort.

Comparing Vyvanse alternatives: which other ADHD medications can I take?

One of the main reasons you may be looking for a Vyvanse alternative is that, like any drug, this medication can come with several side effects. Common side effects of Vyvanse include blurred vision, dry mouth, irritability, loss of appetite, and insomnia to more serious side effects such as high blood pressure. Vyvanse may not be working well for you to treat your symptoms of ADHD (Attention Deficit Hyperactivity Disorder) but there are plenty of other treatment options to look at. Read on to find out more. Let’s take a quick look at Vyvanse before we dive into the alternatives.

What is Vyvanse?

Vyvanse is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire PLC. Vyvanse is the brand name of lisdexamfetamine dimesylate, a derivative of amphetamine. It is a prescription drug belonging to a class of drugs known as Central Nervous System stimulants.

Vyvanse is used to treat ADHD (Attention Deficit Hyperactivity Disorder). It is a stimulant medication but is also classed as a Schedule II controlled substance. As a controlled substance, doctors usually prescribe small doses. It can be used to treat adult ADHD, adolescents, and children over the age of 6 years old.

The active ingredient in Vyvanse is called lisdexamfetamine dimesylate. By working on the central nervous system, Vyvanse increases activity in areas of the brain that help you with your concentration and behavior. It works specifically on the chemicals dopamine and norepinephrine in the brain. These neurotransmitters, dopamine, in particular, are involved in feelings of pleasure, focus, and finding things interesting. Stimulant medications reduce the symptoms of ADHD, making conditions such as inattention, poor decision-making, and poor impulse control much less of a daily problem.

Vyvanse can also be used to treat moderate to severe binge eating disorders. Vyvanse is not however recommended for weight loss and obesity.

Is there a generic for Vyvanse?

Generic Vyvanse is not yet available in the United States. There are other ADHD medications with generic alternatives available.

What ADHD medications are alternatives to Vyvanse?

Choosing the best medication for the treatment of ADHD can be a long process involving adjusting the dosage to achieve the greatest effect with the fewest side effects. Your doctor must take into consideration your medical and personal history e.g. mental health conditions, genetics, and past side effects as well as other factors.

Below are some alternative medications, some are stimulant medications like Vyvanse, and others are non-stimulants.

Stimulant Medications

Adderall (amphetamine and dextroamphetamine)

Adderall contains four different kinds of amphetamine salts – amphetamine sulfate, amphetamine aspartate, dextroamphetamine saccharate, and dextroamphetamine sulfate. In contrast, Vyvanse contains the prodrug lisdexamfetamine, which is metabolized into L- lysine, and dextroamphetamine once it is in the body.

As the primary active component in both medications is dextroamphetamine, they have similar effects. Differences are seen in the onset of action time. Vyvanse takes around three hours to work. If the chewable tablet is taken on an empty stomach it will take slightly longer. Adderall takes about two hours. The effects of both drugs persist for up to 16 hours. Unlike Vyvanse, Adderall is not approved for binge eating disorders. Adderall XR (extended-release) is a long-acting, once-daily formulation that is also available.

Concerta (methylphenidate)

Concerta is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) in children aged six to 18 years, and sometimes in adults too. Concerta is taken orally as a tablet.

Vyvanse and Concerta have different active ingredients. The active component of Concerta is methylphenidate which works in a similar way to Vyvanse as they belong to the same class of drugs. Concerta does not last as long as Vyvanse, with therapeutic effects lasting only 12 hours for Concerta, versus up to 16 hours for Vyvanse. Unlike Vyvanse, Concerta is not approved for binge eating disorders.

Ritalin (methylphenidate)

Ritalin is a central nervous system stimulant just like Vyvanse. Like Concerta the generic name for Ritalin is methylphenidate. Ritalin is used for the treatment of ADHD and has an additional indication for narcolepsy that Vyvanse does not have.

Vyvanse and Ritalin are from the same class of drugs but they work slightly differently. Vyvanse works to increase catecholamines in the neuronal synapse by stimulating their release, while Ritalin blocks the reuptake of the catecholamines to effectively leave more free catecholamines in the neuronal synapse.

Dexedrine (dextroamphetamine)

Dexedrine is a psychostimulant medication prescribed to treat attention deficit hyperactivity disorder (ADHD). Dexedrine also acts on the central nervous system, increasing the number of neurotransmitters, dopamine and norepinephrine in the brain. Dexedrine helps to improve a person’s focus and concentration and reduces hyperactivity and impulsive behavior.

Dexedrine is composed completely of dextroamphetamine. It is available in tablet form and as capsules called Dexedrine Spansule. Dexedrine tablets are short-acting and effective for four to six hours. They are usually taken two or three times per day. Dexedrine Spansule is extended-release, and so is effective for eight to 12 hours. When the capsule is taken, a first dose is released immediately, and the remaining medication is released gradually. It is taken once per day.

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Non-stimulant Medications

Strattera (atomoxetine)

The generic name for Strattera is atomoxetine. It belongs to the drug class known as serotonin-norepinephrine reuptake inhibitors (SNRIs) and is not a central nervous stimulant like Vyvanse.

Intuniv (guanfacine)

Intuniv is a prescription medicine used to treat ADHD alone or alongside ADHD stimulant medicine. As it belongs to a different class of drugs than Vyvanse, the side effect profile of this drug differs.

We have given you a few alternatives to Vyvanse to think about but you should always seek medical advice from your prescribing medical professional when changing medication. Never stop taking the medication without consulting your healthcare provider and always tell them what type of medications you are taking, including over-the-counter meds and supplements.

IBS vs colon cancer

It’s easy to get Irritable Bowel Syndrome (IBS) confused with many other gastrointestinal disorders, including colon cancer because they can present with similar symptoms. Despite similar symptoms, IBS does not put a person at higher risk of developing colon cancer but there are some additional warning signs of colon cancer to look out for. Knowing the difference between the symptoms of IBS and colon cancer is important so you can get treated as early as possible and save yourself a lot of worries.

What is IBS?

IBS is a chronic condition that affects the functioning of your bowels. The condition affects the large intestine, also known as the colon. According to The American College of Gastroenterology, IBS affects 10-15% of the U.S. population. It is a difficult condition to manage but effective treatment options are available alongside lifestyle changes.

Symptoms of IBS

  • Abdominal pain that is reoccurring
  • Changes in bowel movement e.g. constipation or diarrhea
  • Incomplete bowel movements
  • Bloating
  • Cramping
  • Mucus in stools

Diagnosis

To aid diagnosis of IBS, your doctor will first discuss your medical history with you including:

  • Current medications taken
  • Recent infections
  • Recent stressful events
  • Any diet and foods triggers you can identify

Family history is also important including a history of:

  • Celiac disease
  • Colon cancer
  • Inflammatory bowel disease (IBD)

Your healthcare provider will look for a certain pattern in your symptoms over time to diagnose IBS. You should contact your healthcare provider right away if your symptoms get worse or if you have new symptoms.

Treatment options

The American College of Gastroenterology guidelines consider the following treatments as appropriate for IBS:

  • Exercise, diet, and dietary changes
  • Soluble fiber in the diet
  • Interventions that modify the microbiota: prebiotics, synbiotics, probiotics, and antibiotics
  • Antispasmodics and peppermint oil
  • Antidepressants
  • Psychological interventions
  • Pro-secretory agents: linaclotide (Linzess), plecanatide (Trulance), and lubiprostone (Amitiza)
  • Eluxadoline (Viberzi)
  • Alosetron (Lotronex)
  • Rifaximin (Xifaxan)
  • Loperamide
  • Serotonergic agents
  • Polyethylene glycol (Plenvu)
  • 5-aminosalicylates

What is colon cancer?

Colon cancer or colorectal cancer is the third leading cause of cancer-related deaths in men and women according to The American Cancer Society. Colorectal cancer develops when you have growths in your colon or rectum. The terms colon cancer or rectal cancer can be used depending on where the cancer starts.

Symptoms of colon cancer

Some of the most common symptoms of colorectal cancer include:

  • Change in bowel habits
  • Diarrhea
  • Constipation
  • Incomplete bowel movement
  • Rectal bleeding with bright red blood
  • Blood in the stool making it look black
  • Cramping
  • Abdominal pain
  • Weakness and fatigue
  • Unexplained weight loss

Diagnosis

Some of the screening tests for colon cancer include:

  • Colonoscopy or sigmoidoscopy – detects polyps, to prevent them from developing into cancer cells
  • Biopsies can be taken if abnormalities are seen during a colonoscopy or sigmoidoscopy and examined under a microscope
  • A stool test – looks for blood in your stool
  • Blood tests to test for anemia, infections, and digestive problems
  • Imaging tests such as X-ray or CT scan to obtain detailed pictures of the colon

Colorectal cancer screening is important because colorectal cancer in its early stages usually doesn’t produce any symptoms.

Treatment options

Your doctor will talk with you about lifestyle risk factors such as obesity, poor diet, alcohol intake, lack of physical activity, and smoking, which are linked to colon cancer. Your doctor will also discuss in depth your personal/family history of:

  • Colorectal cancer or adenomatous polyps
  • Inflammatory bowel disease
  • Inherited syndromes
  • Type 2 diabetes
  • Race and ethnic background

Treatment for colorectal cancer is determined by the stage of cancer and other factors. Various types of treatment may be combined at the same time or used after one another. In the early stages, local treatment of surgically removing cancer may be carried out. This may move on to radiation therapy and chemotherapy or targeted therapies using drugs such as Erbitux.

The table below shows how IBS and colon cancer are similar and how they differ.

SymptomIBSColon Cancer
Abdominal cramp or painYesYes
Changes in bowel habitsYesYes
BloatingYesYes
Excess gasYesYes
Incomplete bowel movementYesYes
DiarrheaYesYes
ConstipationYesYes
Whitish mucus in stoolYesYes
Blood in stoolNoYes
Tiredness/FatigueNoYes
Rectal bleedingNoYes
Unexplained weight lossNoYes

Other conditions similar to IBS and colon cancer

In addition to colon cancer, your doctor will want to rule out inflammatory bowel disease (IBD) such as Crohn’s disease and ulcerative colitis which disrupt the gastrointestinal tract. This family of disorders shares symptoms with IBS and colon cancer.

IBD is a condition in which the colon is inflamed over a long period of time. This prolonged inflammation raises the risk of colorectal cancer. People who have had IBD for many years, especially if untreated, often develop abnormal cells that can change into cancer over time.

Always speak to your doctor about worsening symptoms or new symptoms that may arise.

How to lower blood sugar fast

High blood sugar, also known as hyperglycemia, can happen if you are a diabetic for many different reasons, including being unwell, eating more than planned, not producing enough insulin in your body, unplanned physical activity, and stress. Untreated hyperglycemia can lead to serious health problems.

The vast majority of hyperglycemia cases are mild but when things get serious you need to know what to do fast. If it is an emergency and you need to reduce blood sugar levels immediately, use insulin. An extra dose of insulin can be taken if you have either type 1 or type 2 diabetes. The amount depends on the situation and your doctor’s recommendation. It is important you know when to seek medical attention from an emergency room. Read on to find out how to lower blood sugar fast.

Take rapid-acting insulin

If it is an emergency and you need to lower blood sugar quickly, use insulin. An extra dose of insulin can be taken if you have either type 1 or type 2 diabetes. The amount depends on the situation and your doctor’s recommendation. It is important you know when to seek medical attention in an emergency.

Take your prescribed medication

Take your diabetes medication regularly as instructed by your doctor and check your blood sugar levels as instructed.

Monitoring your blood sugar levels

As a diabetic, monitoring your blood sugar level is unquestionably the best way to know what is going on inside your body. Keeping your blood glucose under tight control undoubtedly reduces the chance of developing complications. Using a blood glucose meter for glucose monitoring is an essential tool in your diabetes management. How often you check your blood sugar depends on the type of diabetes you have.

Individual blood glucose test strips are great for knowing immediately how your diabetes is controlled. It is equally important to know how you are doing over weeks and months. The A1c test gives us this information as it looks at how good your blood glucose control has been over a period of 3 months.

The A1c test is a great test for a diabetic woman who wants to get pregnant. You can find out if your blood glucose has been well controlled before conceiving. If it has not, you can wait until you have good control. In this way, you reduce the possibilities of complications with your baby.

When to check your blood sugar levels

Type 1 diabetes, adult: Check at least twice daily, up to 10 times a day. You should perform tests before breakfast, at fasting, before meals, sometimes 2 hours after meals, before and after physical activity, and at bedtime.

Type 1 diabetes, child: Check at least four times daily. You should perform tests before meals and at bedtime. Tests may also be required 1–2 hours after meals, before and after exercise, and overnight.

Type 2 diabetes, people using insulin or other management medications: The recommended frequency of testing varies depending on insulin dosage and the use of any additional medications.

Manage carb intake

Carbohydrates are the primary source of energy for muscles, and glucose is the carbohydrate that causes the pancreas to release insulin. Carbohydrates cause the triglyceride level to rise in the blood. However, this usually happens if the carbohydrate in your diet is largely refined, where your total calorie intake is high or where your blood sugar control is poor. When insulin isn’t present or is not effective more carbohydrate raises the blood glucose higher causing blood sugar spikes.

You need to choose your type of carbohydrate carefully. If you have too much-refined carbohydrates e.g white bread and not enough complex carbohydrates, your triglycerides can rise. The way to eat the right amount of carbohydrates without increasing your blood sugar is to eat low glycemic index (GI) and high fiber carbohydrates. Your healthcare provider or dietician will give you advice on creating a diabetes diet plan with the best foods tailored to you.

Read our blog on what foods to avoid with diabetes for more information.

Drink water

By drinking water when your blood sugar gets high, your body tries to flush out that excess sugar as quickly as possible. Drinking enough water could help you keep your blood sugar levels within a healthy range.

Exercise

With exercise, insulin levels can lower blood sugar and increase insulin sensitivity. While exercising, your body is better able to use insulin and helps move sugar from your blood into your cells for storage. During muscle contractions, your cells take up glucose for energy and use it whether insulin is available or not, resulting in lower blood sugar.

It is very important to remember that you should not exercise if ketones are present in your urine as this can make your blood sugar go even higher.

Always seek medical advice from your health care provider for your diabetes care.

Other ways to manage your blood sugar

  • Dietary changes
  • Monitor your body weight to keep within a healthy weight range to avoid obesity
  • Drink alcohol moderately
  • Keep a logbook of blood sugar readings
  • Becoming totally aware of your own symptoms for low/high blood glucose

FAQs

What are the symptoms of high blood sugar levels?

The following symptoms occur:

  • Headaches
  • Blurred vision
  • Excessive thirst
  • Dry mouth
  • Frequent urination
  • Tiredness
  • Weight loss
  • Fruity smell to your breath
  • Thrush and bladder infections

High sugar levels slowly erode the ability of cells in your pancreas to make insulin. Frequent and prolonged high blood sugar levels can lead to diabetic ketoacidosis (DKA). As the name suggests, your blood becomes acidic due to the presence of high levels of ketones. The smell of acetone on the breath is one of the classic ways your doctor can make a diagnosis.

Symptoms of ketoacidosis:

  • Extreme tiredness and drowsiness
  • Nausea and vomiting
  • Weakness
  • Rapid breathing
  • Confusion

Diabetic ketoacidosis is a medical emergency that needs to be treated immediately.

What are normal blood sugar levels?

The blood glucose level is the amount of glucose in the blood. According to the American Diabetes Association (ADA), healthy blood sugar levels for a person without diabetes are:

  • Fasting blood sugar level – under 100mg/dL (in the morning before eating)
  • 1 hour after eating 90-130mg/dL
  • 2 hours after eating 90-110mg/dL
  • 5 or more hours after eating 70-90mg/dL

What are the complications of high blood sugar levels?

Diabetes complications can occur if your diabetes is not treated correctly, issues it can cause are:

  • Heart disease leading to a heart attack
  • Kidney disease
  • Vision loss e.g. cataracts, glaucoma
  • Foot and skin problems e.g. dry skin, loss of elasticity of the skin, or ulcers on the feet
  • Blood vessel damage
  • Nerve damage

Some complications of diabetes can lead to life-threatening problems if they are not picked up and treated on time. Read our blog on the complications of diabetes for more detailed information.

What is pre-diabetes?

Prediabetes is when your blood sugar is high, but the blood test results are not high enough to be classified as diabetes. An oral glucose tolerance test is used to diagnose prediabetes with a blood sample.

Your healthcare professional will discuss your risk factors for diabetes such as your family history, other health conditions, and your current lifestyle. After gathering all this information advice will be given on how to bring your blood sugar levels into a healthy range. This will also bring additional health benefits.

Lifestyle changes including eating a healthy diet, and improving your knowledge of healthy foods and low GI foods are very important when you have been diagnosed as borderline diabetic. A dietitian can put together a pre-diabetes diet and meal plan with you by looking at:

  • Calorie intake, including high fiber, particularly soluble fiber, and wholegrain foods to keep you fuller for longer
  • Lowering your carb intake
  • Looking at low glycemic index foods (GI foods) e.g. lentils, legumes
  • Low-fat alternatives
  • Healthy fats e.g. olive oil
  • Omega-3 fatty acids and antioxidants e.g. salmon

Read our blog on top 20 best snacks for diabetics for ideas on healthy choices.

Your care team will also discuss ways to increase your physical activity, and how to keep your cholesterol and blood pressure under control to help reduce your risk of diabetes. Metformin is often recommended for individuals with prediabetes if healthy eating and lifestyle changes are not enough.

Which foods control blood sugar levels?

To lower blood sugar levels, and reduce blood sugar response some food choices are particularly useful to be included in a diabetic meal plan:

  • Non-starchy vegetables
  • Plain yogurt packed with healthy probiotics and no added sugar
  • Chia seeds
  • Chickpeas
  • Flaxseeds
  • Fatty fish
  • Blueberries

The aim is to achieve a diet balanced with nutrients and vitamins, like vitamin E, omega-3 fatty acids, and magnesium which control blood sugar levels and improve heart health.

What is the average blood sugar level?

The average blood sugar level differs based on age, how long you have had diabetes, medication taken and other medical illnesses you may have. The tables shown earlier in this blog give you an idea of the ideal levels, but your healthcare team will advise you on your ideal levels.

What medications can raise blood sugar levels?

Many types of medications and some OTC (over-the-counter) medications raise blood sugar levels, but this does not mean they can not be taken if they are needed. You must work with your doctor on the correct way to use them. Some prescription medicines that increase blood sugar levels are steroids, birth control pills, statins, drugs that treat mental health issues, medication for acne, and high doses of asthma medicines. Some OTC medicines that increase blood sugar levels include decongestants, cough syrups, and supplements.

Common medications that cause an increase in blood sugar levels are:

  • Beta-blockers e.g. atenolol
  • Diuretics
  • Corticosteroids e.g. prednisone for rheumatoid arthritis treatment
  • Over the counter supplements e.g. niacin
  • Antidepressants e.g. selective serotonin reuptake inhibitor drugs like citalopram

Which medications can be used to treat Type 2 diabetes?

There are several prescription drugs that are commonly used to treat Type 2 diabetes:

Can stress cause high blood sugar levels in non-diabetics?

When you are stressed the hormone cortisol is released. Cortisol blocks the effects of insulin in your body. This means sugar is not moved from the blood into the cells and can cause high blood sugar levels in non-diabetics. If cortisol is released too often or its effects last too long it raises insulin levels and can result in insulin resistance and type 2 diabetes.

High-risk factors, such as high blood pressure, a history of polycystic ovary syndrome (PCOS), or heart disease, and race should be taken into consideration.

What is hypoglycemia?

The condition of low blood sugar levels is called hypoglycemia. Having lower blood sugar levels when you have diabetes (also called diabetes mellitus) is a consequence of your diabetes treatment. As a diabetic, you are in constant combat with hyperglycemia which is responsible for most of the long-term and short-term complications of the disease. Hypoglycemia can occur because drugs and treatments are not always perfect. If you take too much of a certain drug, exercise too little, or don’t eat enough, your blood glucose can drop to low levels at which symptoms can develop.

When these symptoms develop eat a snack to raise levels e.g. fruit juice or honey. In some cases, a glucagon emergency kit may be needed.

Diabetes insipidus vs mellitus

Diabetes insipidus is not related to diabetes mellitus (type 1 diabetes or type 2 diabetes) despite the name. Diabetes Insipidus is a rare condition. It is caused due to problems related to a hormone called anti-diuretic hormone (ADH). There is no increase in blood sugar levels, unlike diabetes mellitus.

Diabetes mellitus and diabetes insipidus have very few similar symptoms. The only real similarity is the first word of their name. These diseases cause different problems in the human body and have very different treatments. Let us understand the main difference between diabetes insipidus vs. diabetes mellitus.

What is diabetes insipidus?

Diabetes insipidus is a hormone disorder. It occurs when there is a problem with the secretion of antidiuretic hormone (ADH) or vasopressin. It can also occur if your body doesn’t use the hormone effectively. There are four types of diabetes insipidus:

  1. Central diabetes insipidus – damaged pituitary gland or hypothalamus gland
  2. Nephrogenic diabetes insipidus – often caused by chronic kidney disease
  3. Dipsogenic diabetes insipidus – often caused by damage to the thirst mechanism
  4. Gestational diabetes insipidus – caused by an enzyme made by the placenta which destroys ADH in the mother

Symptoms of diabetes insipidus

The main symptoms of diabetes insipidus are:

  • Exhaustion
  • An extreme thirst that can not be quenched, known as polydipsia
  • Excessive urination known as polyuria

The amount of urine most people produce is 1-3 quarts(qt) per day. People who have diabetes insipidus may have urine production up to 20 quarts a day. They may have to get up multiple times during the night to urinate, they may wet the bed and can appear confused. Diabetes insipidus causes thirst due to dehydration from constant urination. This keeps electrolyte levels e.g. calcium and potassium in the body low, and those affected with diabetes insipidus are commonly tired.

What causes diabetes insipidus?

Diabetes insipidus has several causes. Damage to either the hypothalamus or the pituitary gland can cause diabetes insipidus. This can occur after a head injury, during brain surgery, or when a tumor grows on the glands. Kidney disease and hypercalcemia (excess calcium in the body) or taking certain drugs such as lithium can cause diabetes insipidus too.

How is diabetes insipidus diagnosed?

Diabetes insipidus can be diagnosed with blood tests to check sodium levels and urinalysis using a urine sample. This will be able to tell if your kidney is making enough concentrated urine and if it is dilute urine. Your healthcare professional may also order a water deprivation test and an MRI (magnetic resonance image) scan.

Diabetes insipidus treatment

Your healthcare professional may prescribe medicine to reduce your urine output. This medicine will help your body produce or use ADH more effectively. A drug called desmopressin is a synthetic form of ADH and can be used. Desmopressin comes as a tablet, as a shot, or as a nasal spray.

Medicines like hydrochlorothiazide (a water pill) may also help. Water pills help your body balance salt and water.

If your diabetes insipidus could be caused by tumors or abnormal growths on your hypothalamus or pituitary gland your doctor may suggest surgery to remove the growths.

If a medicine is causing diabetes insipidus, your doctor may prescribe an alternative that won’t cause excessive thirst and urination. Discuss which treatment option is best for you with your doctor.

Living with diabetes insipidus

There is no cure for diabetes insipidus, only management of symptoms to improve quality of life. Medicine can help prevent the constant thirst and excessive urination that comes with this condition.

What is diabetes mellitus?

Diabetes Mellitus is a condition that causes high blood sugar or high blood glucose levels in the blood.

Symptoms of diabetes mellitus

Having too much glucose in your blood can cause these early symptoms of diabetes:

  • Tiredness
  • Hunger
  • Urinating more often
  • Thirst
  • Dehydration
  • Blurred vision
  • Slow-healing cuts/sores
  • Yeast infections

What are the causes of type 1 and type 2 diabetes?

The most important hormone to understand in diabetes is insulin. It is made in your pancreas which is located just behind your stomach. Insulin is the major metabolic hormone of carbohydrate metabolism.

Your pancreas detects your glucose falling and turns off the release of insulin. This stops your blood sugar from going too low (hypoglycemia). At the same time, your liver begins to make more glucose in your blood. This whole system helps to keep the level of glucose in your body correctly.

Insulin is the only means that the body has of lowering blood glucose levels. When this system fails diabetes occurs. Each type of diabetes involves the pancreas not functioning properly.

How is diabetes mellitus diagnosed?

Tests to diagnose both forms of diabetes and :

  • Fasting blood sugar test – After an overnight fast your blood glucose level will be measured
  • Glucose tolerance test – After an overnight fast your blood glucose level will be measured, followed by a drink containing glucose. Your blood sugar will then be retested every half hour for two hours to see how your body is responding
  • Random blood sugar test – This test does not require an overnight fast but is taken any time of the day
  • Hemoglobin A1c testThis test measures the average blood sugar control over the last two to three months. Often used to check if a person has prediabetes

Diabetes mellitus treatment

The only treatment for type 1 diabetes is insulin. If you have this type of diabetes your body is unable to produce insulin, therefore you need to inject it directly into your body. As a result, there is no cure for type 1 diabetes.

A wide variety of diabetes medications is available if lifestyle changes do not work in the first instance. Most medications for type 2 diabetics are oral drugs. However, a few come as injections. Some people with type 2 diabetes may also need to use insulin.

Living with diabetes mellitus

Unfortunately, type 1 diabetes can not be prevented. You may lower your risk of developing type 2 diabetes by lifestyle changes and developing new routines, such as:

  • Keeping to a healthy weight to avoid obesity
  • Increase your activity levels to aid in weight loss
  • Eating a healthy diet to help control cholesterol levels
  • Reduce smoking and blood pressure

The table below shows some of the differences between diabetes insipidus and diabetes mellitus.

Diabetes InspidiusDiabetes Mellitus
CauseUsually caused by a hormone imbalanceType 1 - Autoimmune Disease Type 2 - Genetics, lifestyle, infection
Volume of urineExtremely excessiveExcessive
Blood glucose levels elevatedNoYes
Glucose in urineNoYes
Concentration of urineDilutedNormal
Cholesterol levelsNo increaseIncreased
HungerNormalExcessive hunger
Ketone formationNoYes

What is a prescription assistance program?

A prescription assistance program is a government or privately-funded program that helps low-income individuals who cannot afford their prescription medications. These programs are often run by pharmaceutical companies, and they offer access to medications for eligible patients who cannot afford them. We will discuss the different types of prescription assistance programs available, and how to apply for them.

Most drug programs are provided to people in need who cannot afford medical care, are under-insured or uninsured, and need financial assistance with accessing their prescribed medications. You may be eligible for free medicine if you do not have health insurance or do not have coverage for your medication. We cover the most common types of prescription assistance programs below.

Pharmaceutical company prescription assistance programs

These prescription assistance programs are offered by pharmaceutical companies to help people who cannot afford their brand-name medications. The eligibility requirements and the medications that are covered vary from program to program, so you will need to check the specifics of each program. However, most of these programs require that you have no prescription insurance coverage and meet certain income requirements.

Manufacturer copay assistance programs for prescription drugs

Manufacturer copay assistance programs are intended to help commercially insured individuals afford the cost of expensive prescription drugs, by covering a portion or all of the deductible and copay for some medications. This financial assistance is offered to eligible individuals who meet certain criteria set by the manufacturer.

Government prescription assistance programs

There are several different government prescription assistance programs available, each with its own set of eligibility requirements. Some programs are available to all Americans, while others are only available to people who live in specific states or who meet certain income requirements. The most common government prescription assistance programs are:

  • the Medicare Part D prescription drug coverage program
  • the Medicaid prescription drug coverage program
  • the Veterans Affairs prescription drug coverage program

State pharmaceutical prescription assistance programs (SPAP)

Most states have their own prescription assistance program, and the eligibility requirements vary from state to state. To find out if you are eligible for a prescription assistance program in your state, you can visit the website of the National Association of State Directors of Developmental Disabilities Services or contact your local social services or community health center.

State Pharmaceutical Assistance Programs (SPAPs) are programs run by the state that assist low-income individuals in paying for their prescription drugs.

How to apply for prescription assistance programs

To apply for a prescription assistance program, you will need to provide some information about yourself and your prescription medications. This information will usually include:

  • your name, address, and contact information
  • information about your prescription medications, including the name of the medication, the dosage, and how often you take it
  • proof of income (if required)
  • Once you have gathered this information, you can apply for prescription assistance programs in several ways:
  • online: many prescription assistance programs have online applications that you can complete
  • by mail: you can also apply for prescription assistance programs by mailing in an application
  • over the phone: some prescription assistance programs have toll-free numbers that you can call to apply
  • in person: you can also visit a local social service or community health center to apply for prescription assistance programs

Do I qualify for a prescription assistance program?

The eligibility requirements for prescription assistance programs vary from program to program, so it is important to check the specifics of each program. The most common eligibility requirements are:

  • you must be a U.S. citizen or legal resident
  • you must have no prescription insurance coverage
  • your health care insurance does not cover the medication cost
  • you must meet certain income requirements

If you need help accessing your medication from a prescription assistance program, NiceRx can help! Get started with your online enrollment and find out if you are qualified.

Biosimilar vs generic: which is better?

Biosimilar drugs are often confused with generic drugs. Biosimilars and generic drugs are versions of brand-name drugs and may offer cost-saving treatment options to patients. Brand manufacturers begin with exclusivity protection for many years to allow them to profit from their research and development of the drug. During this time no biosimilars or generics can compete with the brand. After patent expiry, biosimilars and generics can enter and gain market share.

Biosimilars and generics are both approved by the U.S. Food and Drug Administration (FDA) but biosimilars require a specific regulatory approach distinct from that of generics. The Biologics Price Competition and Innovation Act of 2009 shortened the FDA approval process for biosimilar drugs to avoid duplicating costly clinical trials.

Biosimilars are not generic medicines, and there are important differences between biosimilars and generic drugs. Read on to find out more.

What is a biosimilar drug?

It is a biological product that is very similar to another biological product known as the reference biologic (the original biologic drug).

e.g. the brand product Humira used to treat rheumatoid arthritis is the reference biologic and Amjevita is its biosimilar product manufactured by Amgen.

Biosimilar medicines have certain features:

  • Large complex molecules make them challenging and costly to produce
  • Biological medicines originate from living cells, such as humans, animals, or microorganisms, so they have sophisticated and costly manufacturing processes
  • Highly similar to the reference product but can not be identical as these drugs originate from living cells
  • Minor differences to the reference product within strict limits
  • A biosimilar has no clinically meaningful differences in safety, purity, and effectiveness from an existing FDA-approved reference product
  • Biosimilars are more complicated to develop and the FDA regulatory pathway for approval is more complex

Biological products can include a wide range of products including vaccines, blood components, gene therapy, tissues, and proteins, like monoclonal antibodies and cell signaling proteins.

What is a generic drug?

A generic drug is a medicine that contains the same active ingredient as the branded medicine and is a chemical copy of the branded drug.

e.g. the brand name drug Glucophage is used to treat diabetes but its generic drug product is metformin.

Generic drugs have certain features:

  • Small molecule structures
  • Its manufacturing process is easy and predictable
  • Created in a laboratory with chemically identical ingredients to their reference products
  • Provides the same clinical benefit as the brand name medicine
  • Minor differences to the reference product within strict limits
  • They go through FDA approval to show their safety and effectiveness.

Another important difference that clearly sets biosimilars and generics apart is interchangeability. The approval of a drug as a biosimilar does not automatically mean it is interchangeable with its reference product. A pharmacist can not substitute a biosimilar product with another product, unlike generics that can be automatically substituted with other generic versions. According to the FDA, a biosimilar product cannot be substituted at the pharmacy level without the intervention of the prescribing healthcare provider. For biosimilars to be approved as interchangeable, they must meet further criteria during the approval process, unlike generics.

Key differences between generic drugs and biosimilar drugs

FeatureBiosimilarsGenerics
FDA definitionA biosimilar is highly similar to its reference biological product and has no clinically relevant differences to the reference product in terms of safety, purity, and potencyA generic drug is identical to a branded drug in dosage form, safety, strength, route of administration, quality, performance characteristics, and intended use
Size & structureLarge and complexSmall and simple
ManufacturingBiological process using living cellsChemical synthesis using chemical ingredients in an ordered sequence
Administration routeInjectionOral
StabilityUnstable as sensitive to handling and storage conditionsStable
ImmunogenicityYesNo
FDA approval processPreclinical (animal) and clinical (human) data to establish safety and effectiveness are generally requiredPreclinical (animal) and clinical (human) data to establish safety and effectiveness are generally not required
Reference medicationReference drug ( the original) is an FDA approved biologicReference drug (brand name medication) is an FDA approved drug
NamingEach biosimilar has its own brand name consisting of the same non-brand name of the reference biologic plus a suffix of four lower case letters e.g. infliximab-axxq its reference product is Remicade (infliximab)The generic drug has the same chemical/active ingredient as the branded drug

ADD vs ADHD

Have you heard the term ADD used instead of ADHD and has it caused you confusion? That’s because ADD is an outdated term that is rarely used these days. The symptoms of the two conditions set them apart from one another, therefore it is important to define them separately. We cover the differences between the two terms, including their symptoms, diagnosis and treatment.

What is ADD?

ADD is the abbreviation for Attention Deficit Disorder. It was first used in 1980 to describe children that had a hard time paying attention and named the condition ADD in the Diagnostic and Statistical Manual of Mental Disorders. As time went on experts also noticed some of these children struggled with hyperactivity and impulsivity. At this point, all symptoms were combined into one group and renamed ADHD (Attention Deficit Hyperactivity Disorder) and the American Psychiatric Association (APA) stopped using the term ADD in 1987.

What is ADHD?

ADHD is the abbreviation of Attention Deficit Hyperactivity Disorder characterized by inattention, hyperactivity, and impulsivity. It is a neurodevelopmental disorder that is typically diagnosed in childhood, commonly in males but underdiagnosed in females. According to the Centers for Disease Control and Prevention, there are an estimated 6.4 million children and adolescents diagnosed with ADHD in the United States.

Mental health professionals have identified three types of ADHD, based on the main symptoms involved:

  • Inattentive type ADHD

Previously known as ADD and now sometimes described as ADHD with inattentive presentation)

  • Hyperactive-impulsive ADHD
  • Combination of inattentive and hyperactive-impulsive type ADHD

ADHD symptoms can vary from person to person, depending on the subtype of ADHD.

Inattentive type

Symptoms of inattention:

  • Disorganization
  • Struggle to pay close attention to details, which may result in frequent mistakes
  • Often does not follow through on instructions
  • Appear to not listen
  • Can get frustrated performing tasks or activities requiring mental effort
  • Distractibility
  • Misplace items
  • Careless mistakes
  • Forgetfulness
  • Daydreaming

Hyperactive/impulsive type

Symptoms of hyperactivity:

  • Behavior problems
  • Impulsive behaviors
  • Fidgeting with hands and feet or squirming
  • Trouble staying seated
  • Difficulty playing or doing leisure activities quietly
  • Excessive talkativeness, including interrupting in conversation
  • Difficulty waiting
  • Interrupt or intrude on others

Combination-type ADHD

The combined type of ADHD shows a mixture of inattentive and hyperactive/impulsive type symptoms and behaviors.

Diagnosis of ADHD

Diagnosing ADHD requires an in-depth analysis of an individual’s symptoms of ADHD, their medical history, including any mental health conditions, and their academic, social, and emotional development.

Children need to have 6 or more symptoms (5 or more for adult ADHD diagnosis) for at least 6 months and

  • Present with symptoms before the age of 12
  • Present with symptoms in at least two different settings, including at school, home, work, with friends, or during other activities
  • Present with symptoms severe enough to interfere with daily life at school, work, or in social situations and impact quality of life

This evaluation is completed by qualified clinicians who can then make an ADHD diagnosis based on criteria from the Diagnostic and Statistical Manual, 5th Edition (DSM-5), which is used by mental health professionals in the United States to diagnose all psychiatric conditions.

Treatment options

Treatments for ADHD may include medications such as:

These drugs reduce the symptoms of ADHD by working on the central nervous system. They increase activity in areas of the brain that help with concentration and behavior. They work specifically on the brain chemicals dopamine and norepinephrine. Dopamine in particular is involved in allowing you to feel pleasure, focus, and find things interesting.

  • Counseling or behavioral therapy – behavior therapy includes behavior-changing strategies like setting and following routines. Counseling allows individuals to talk through their difficulties and find solutions
  • Parental and educational support – parents, teachers, school counselors, and family members can learn behavior therapy to support the strategies suggested
  • ADHD education

Some useful websites to start are CHADD https://chadd.org and American Academy of Child & Adolescent Psychiatry www.aacap.org

Jardiance side effects and how to avoid them

Jardiance is used to control blood glucose levels and protect the heart in people with type 2 diabetes mellitus. It is often prescribed with other diabetes medications such as metformin. Jardiance can cause adverse reactions as can all medications. The more common side effects of Jardiance tend to be drowsiness and feeling more thirsty than usual. It’s important to talk to your healthcare professional for medical advice about possible side effects that trouble you or are persistent. Learn more about Jardiance side effects and how to avoid them.

What is Jardiance?

Jardiance is the brand name of a prescription drug manufactured by Boehringer Ingelheim Pharmaceuticals. It is an FDA-approved medicine prescribed to adults with type 2 diabetes and heart disease to:

  • Improve blood sugar levels  in adults with type 2 diabetes mellitus alongside diet and exercise
  • Lower the risk of cardiovascular death from a heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease

This medication can help you lower your blood sugar levels when taken alongside dietary and lifestyle changes. It causes you to excrete more sugar in your urine than you would normally. This lowers your blood sugar and helps to reduce your risk of health conditions like cardiovascular disease. Jardiance can not be used to treat type 1 diabetes or used during breastfeeding. It is not known if this drug passes into breast milk.

Jardiance active ingredients

The active ingredient in Jardiance is called empagliflozin. It is classed as a sodium-glucose co-transporter 2 inhibitor (SGLT2 inhibitor). It lowers your blood sugar levels by causing you to lose more sugar in your urine than you usually would.

Your kidneys help recycle sugar back into your blood from your urine with the help of a protein called sodium-glucose co-transporter 2 (SGLT-2). Empagliflozin blocks this protein from working, reducing how much sugar your kidneys recycle. This makes you lose more sugar in your urine, rather than it being recycled back into your blood.

Jardiance comes as an oral tablet that you take with water. Doses available are 10mg and 25 mg. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and take your next dose at the regular time.

Jardiance side effects

Common side effects of Jardiance include:

  • Feeling more thirsty than usual
  • Drowsiness
  • A skin rash – this may be itchy and include raised bumps and blisters that leak fluid, and may cause your skin to redden
  • An increase in cholesterol levels (this may show up in blood tests)
  • Vaginal yeast infection
  • Genital yeast infection in men
  • Raised cholesterol levels
  • Urinary tract infection (UTI)
  • Increased urination
  • Lightheadedness
  • Weight loss

In rare instances, Jardiance can cause more serious side effects, including:

  • Severe allergic reactions to the medication e.g. hives
  • A rare but serious bacterial infection that damages tissue under the skin (necrotizing fasciitis) in the area between the anus and genitals (perineum), called Fournier’s gangrene
  • Diabetic ketoacidosis, a potentially life-threatening condition where your body breaks down too much fat too quickly, causing you to produce high levels of blood acids called ketones
  • An increased risk of serious urinary tract infections
  • A high and potentially harmful increase in your cholesterol levels
  • Low blood pressure (hypotension)
  • Diabetic ketoacidosis symptoms such as stomach pain, unusual tiredness, trouble breathing
  • Kidney problems e.g. kidney disease and patients receiving dialysis
  • Low blood sugar (hypoglycemia) particularly when used with other medications like insulin or sulfonylurea
  • Dehydration

What are the worst side effects of Jardiance?

Jardiance can cause some common side effects such as vaginal yeast infections, genital yeast infections in men, and urinary tract infections. However, Jardiance can cause worse more serious side effects. These include serious allergic reactions, diabetic ketoacidosis, and hypoglycemia. Speak to your doctor for medical advice if you experience any of these side effects.

Does Jardiance cause any side effects on your eyes?

Side effects of Jardiance on the eyes have not been reported in people who took this medication. However, blurry vision and other eye problems can happen when your blood sugar is high.

What does Jardiance do to your perineum?

Jardiance may cause a bacterial infection, called necrotizing fasciitis of the perineum or Fournier’s gangrene. This can damage the tissue beneath the skin between and around the anus and genitals (perineum). This may lead to hospitalization. Speak to your doctor immediately if you have signs of fever, unusual tiredness or weakness, pain, redness, or swelling of the perineum between your anus and genitals.

Jardiance drug interactions

Jardiance can also interact with other medications, which can limit its effectiveness, including:

  • Any other diabetes medications, like insulin or sulfonylureas e.g glyburide
  • Other medications that can lower your blood sugar levels, like diuretics (water pills), corticosteroids, estrogens, oral contraceptives, nicotinic acid, and calcium channel blocking drugs

Talk with your health care provider for medical advice regarding any side effects or drug interactions you may have. Read the medication guide and instructions for use that come with Jardiance for the full drug information. You are encouraged to report the negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How to avoid Jardiance side effects

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional once daily at the same time each day with water. Taking your medication consistently will make a big difference in how well Jardiance works for you.

Your healthcare provider may adjust the dose of Jardiance or your other medications to find the best dosage for your specific needs.

2. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Jardiance will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Jardiance and help manage any possible side effects.

3. Reduce alcohol intake

Excessive alcohol intake puts you at a higher risk of developing chronic inflammation of the pancreas. This is known as pancreatitis and can lead to permanent damage to the pancreas and its ability to manage the production, storage, and release of insulin.

If you are planning to drink alcohol and you have diabetes, aim to always stay within the recommended guidelines. This is the safest way to drink alcohol.

4. Pay attention to your body

Paying attention to how your body feels when taking Jardiance is important, as uncontrolled blood sugar can be fatal. It is useful to keep a diary log of your blood glucose readings and how you are feeling.

Seek immediate medical attention if you feel your blood sugar levels are uncontrolled. Talk to your doctor straight away if you start to experience any side effects of Jardiance when taking it, and if you feel the medication is not working for you.

5. Store Jardiance correctly

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not store in the bathroom.

Knowing how to store your medication is important to make sure it remains as effective as possible. Using expired or improperly stored medication could result in the medication not working properly and even causing unwanted side effects.

 

Ozempic side effects and how to avoid them

Ozempic is used to control high blood sugar in people with type 2 diabetes mellitus. Just like other drugs, it can cause adverse reactions. The more common side effects of Ozempic tend to be diarrhea, nausea, vomiting, and stomach pain. It’s important to talk to your healthcare professional for medical advice about possible side effects that trouble you or are persistent. Learn more about Ozempic side effects and how to avoid them.

What is Ozempic?

Ozempic is an FDA-approved prescription drug made by Novo Nordisk. It is used for the treatment of type 2 diabetes to prevent blood sugar from rising after eating, by slowing the rate of digestion and the release of insulin in your body.

This medicine is also used to lower the risk of a heart attack in type 2 diabetics. It causes your pancreas to secrete more insulin, helping to lower your blood sugar and reduce your risk of major cardiovascular events, like heart attacks and strokes, if you have heart disease.

Ozempic can help you lower your blood sugar levels when used alongside dietary and lifestyle changes. Ozempic is not used to treat type 1 diabetes or diabetic ketoacidosis.

How does Ozempic work?

The active ingredient in Ozempic is semaglutide. It is classed as a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist). Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers glucagon secretion by selectively binding to and activating the GLP-1 receptor.

Unlike many other treatments for type 2 diabetes, semaglutide is not a type of insulin. It is a human hormone that acts on different parts of your body. Semaglutide encourages your pancreas to produce more insulin, helping to lower your blood sugar after you’ve eaten. It also appears to increase the growth of the cells in your pancreas that produce insulin (beta-cells).

The semaglutide injection is injected under the skin (subcutaneous) usually once every 7 days. The injection sites are the thigh, abdomen, or upper arm. The dose you receive is based on your medical condition and your response to treatment. If you miss your weekly dose of Ozempic and there are less than 3 days until your next dose, do not take the missed dose. The Ozempic injection can be stored at room temperature or in the refrigerator.

What happens if I miss a dose of Ozempic?

If you forget to take a dose of Ozempic, take it as soon as you remember. If, however it is nearly time for your next dose, do not take the missed dose. Take your next dose when you would normally take it. Do not double up your doses as this may risk an overdose.

Why have I been prescribed Ozempic?

Ozempic is a diabetes medication that is likely to have been prescribed because the combination of improving diet, increasing exercise, bodyweight reduction, and metformin medication has not achieved adequate blood sugar control for you.

Ozempic is not approved for people with type 1 diabetes and should not be taken by women who are pregnant or breastfeeding. Some of the advantages of taking Ozempic are suppression of hunger and modest weight loss, which are desirable for diabetics.

Do not use Ozempic if you have a personal or family history of thyroid tumors or thyroid cancer or if you have multiple endocrine neoplasia syndrome type 2.

Other common GLP-1 receptor agonists are:

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What are the side effects of Ozempic?

The most common side effects of Ozempic include:

In rare instances, Ozempic can cause more serious side effects, including:

  • An increased risk of thyroid tumors, symptoms such as hoarseness, a lump or swelling in the throat
  • Kidney problems, including kidney failure
  • Serious allergic reactions cause swelling under your skin, normally in your eyelids, lips, hands, or feet. Swelling of your mouth, tongue, or throat leading to shortness of breath
  • Inflammation of your pancreas (pancreatitis). Symptoms of pancreatitis include severe abdominal pain/stomach pain, nausea/vomiting that doesn’t stop
  • Changes in your vision
  • Very low blood sugar (hypoglycemia) causing shakiness, fast heartbeat

For medical advice about side effects, talk with your health care provider and also read the medication guide and instructions for use that comes with Ozempic.

Does Ozempic cause weight loss?

Ozempic is not FDA-approved for weight loss but may reduce your appetite which will help you to lose weight. Patients taking Ozempic in combination with changes to diet and lifestyle will lose on average 14 lbs over 6 to 12 months.

RELATED: Ozempic for weight loss

How long do Ozempic side effects last?

Milder side effects should stop within a couple of weeks of treatment with Ozempic.

Does Ozempic cause hair loss?

Hair loss is not a side effect of taking Ozempic. Hair loss may however occur as a symptom of high blood sugar levels and diabetes. Speak to your healthcare professional if you have concerns about hair loss when using Ozempic.

Does Ozempic cause headaches?

Headaches are a symptom of low blood sugar levels (hypoglycemia). Ozempic may cause low blood sugar when taken in combination with other medication for the treatment of diabetes.

Does Ozempic cause fatigue?

Fatigue or tiredness is a side effect of Ozempic, affecting around 5 % of individuals. Ozempic causes a loss of appetite which reduces calorie consumption. The reduction in energy intake causes fatigue.

Does Ozempic affect your eyes?

Diabetic retinopathy is a condition caused by diabetes and high blood sugar levels that damages the retina at the back of the eye. Patients with diabetic retinopathy are at an increased risk of bleeding or swelling in the back of the eye when using Ozempic.

What are the bad side effects of Ozempic?

Serious side effects of Ozempic include an increased risk of thyroid tumors, kidney failure, severe life-threatening allergic reactions, pancreatitis, and hypoglycemia.

What is the biggest side effect of Ozempic?

The biggest and most serious side effect of Ozempic are life-threatening allergic reactions. Symptoms include swelling of the face, lips, tongue, or throat, trouble breathing, fainting, dizziness, or a very fast heart rate.

Why do I feel so sick on Ozempic?

Slowing down of gastric emptying, stomach upset, and nausea are common side effects of Ozempic and the class of drugs it belongs to. These side effects will normally go away within a couple of weeks of starting treatment with Ozempic. Eat smaller meals to help reduce symptoms of an upset stomach.

Why does Ozempic make you tired?

Ozempic will cause a loss of appetite which will reduce your calorie consumption. The reduction in your energy intake will make you feel tired.

Do Ozempic side effects go away?

Most side effects from Ozempic are short-term and mild. Most of these side effects should go away within a few days or a couple of weeks. If you experience side effects that will not go away, speak to your doctor for medical advice.

Ozempic drug interactions

  • Any medications you take orally to reduce the risk of blood clots (oral anticoagulants) like warfarin
  • Insulin – Ozempic can be used alongside insulin, but your doctor may change the dose of insulin you take and/or how often you use insulin
  • Any other medications that are taken to treat type 2 diabetes

Ozempic warnings & precautions

Don’t take Ozempic if you:

  • Are allergic to the active ingredient semaglutide, or any of the other ingredients in Ozempic
  • Have had, or anyone in your family has had a type of thyroid cancer called medullary thyroid carcinoma (MTC)
  • Have an endocrine system condition called multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Have pancreatitis
  • Have type 1 diabetes (Ozempic is for type 2 diabetes only)
  • Are under 18 years of age

Talk to your doctor before taking Ozempic if you:

  • Have had any problems with your kidneys or pancrease
  • Have ever had diabetic retinopathy
  • Are currently pregnant or are planning to become pregnant
  • Are currently breastfeeding or are planning to breastfeed

Always speak to your healthcare professional for medical advice regarding drug interactions, taking supplements, taking over the counter (OTC) medications, and drinking alcohol when using Ozempic. Healthcare professionals are the most reliable and accurate source of drug information. They can also provide you with a  medication guide for each drug you take.

How to avoid Ozempic side effects

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional once per week, on the same day of the week, as a subcutaneous injection in the upper arm, abdomen, or thigh to prevent you from forgetting your dose. Taking your medication consistently will make a major difference in how well Ozempic will work for you.

Your healthcare professional may adjust the dose of Ozempic or your other medications to find the best dosage for your specific needs.

2. Rotating insulin injection sites

The importance of rotating insulin injection sites is to reduce reactions at the site of the injection, to maintain effective insulin absorption and reduce small fatty lumps or hard lumps that could develop in areas that are continuously used as injection sites. These can interfere with insulin absorption and also cause discomfort. Switching between injecting sites such as the left and right arm or right and left thigh, and moving injection sites within the area will help prevent problems.

3. Store Ozempic correctly

Ozempic should be stored correctly at room temperature (68 to 77 degrees Fahrenheit) and the needle disposed of correctly. Ozempic should be stored in a dry place in its original container.

Knowing how to store your prescription medication is essential in order to make sure the medication will remain as effective as possible. Using improperly stored or expired medication may result in the medication not working properly and potentially causing unwanted side effects.

RELATED: Does Ozempic need to be refrigerated?

4. Discuss medical history

Discussing your medical history with your healthcare professional is important to assist them understand how effectively Ozempic will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your healthcare provider will allow them to pick up any drug interactions with Ozempic and help manage any side effects.

5. Reduce alcohol intake

Excessive alcohol intake increases your chance of developing chronic inflammation of the pancreas called pancreatitis. This condition leads to permanent damage to the pancreas and its ability to manage the production, storage, and release of insulin.

If you are planning to drink alcohol and you have diabetes, aim to always stay within the recommended guidelines. This is the safest way to drink alcohol.

6. Pay attention to your body

Paying attention to how your body feels when taking Ozempic is important, as uncontrolled blood sugar can be fatal. Seek immediate medical attention if you feel your blood sugar levels are uncontrolled. Talk to your doctor straight away if you start experiencing any side effects of Ozempic when taking it, and if you feel the medication is not working for you.

Vyvanse side effects and how to avoid them

Vyvanse can cause adverse reactions. The more common side effects tend to be loss of appetite and stomach ache to more serious side effects such as new or worsening mental health issues. Learn more about Vyvanse side effects and how to avoid them.

What is Vyvanse?

Vyvanse is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire PLC. Vyvanse is the brand name of lisdexamfetamine dimesylate, a derivative of amphetamine.  It is a prescription drug belonging to a class of drugs known as Central Nervous System stimulants. Vyvanse is used to treat symptoms of Attention Deficit Hyperactivity Disorder (ADHD) and moderate to severe binge eating disorder. Vyvanse is not recommended for weight loss and obesity. Vyvanse is a prescription stimulant medication but is also classed as a Schedule II controlled substance. As a controlled substance, doctors usually prescribe small doses.

Other drugs included in the class of Central Nervous System stimulants include Adderall XR, Concerta (methylphenidate), and Ritalin. Vyvanse treats ADHD and binge eating disorders by increasing norepinephrine and dopamine levels, thereby altering the balance of chemicals in your brain.

How does Vyvanse work?

By working on the central nervous system, Vyvanse increases activity in areas of the brain that help you with your concentration and behavior. It works specifically on the brain chemicals dopamine and norepinephrine. Dopamine in particular is involved in feelings of pleasure, focus, and finding things interesting. Stimulant medications reduce the symptoms of ADHD making conditions such as inattention, poor decision making, and poor impulse control much less of a daily problem.

Vyvanse active ingredients

Vyvanse is similar to Adderall. The main difference is that Adderall is a mixture of four different kinds of amphetamine salts (one of which is dextroamphetamine) while Vyvanse only contains one type of amphetamine salt, called lisdexamfetamine.

Vyvanse is a prodrug, meaning lisdexamfetamine is converted into dexamphetamine once it is in the body. An advantage of Vyvanse is that it may less likely be abused. Vyvanse is a federally controlled substance because it has a high potential for drug abuse and can lead to dependence. You should store Vyvanse at room temperature, away from light and moisture, and from children and pets.

Vyvanse belongs to a class of drugs known as amphetamines, that work by blocking the reuptake of norepinephrine and dopamine into the presynaptic neuron and therefore increase the release of these monoamines into the extraneuronal space.

How long does a dose of Vyvanse last in your system?

Vyvanse will work for around 10 to 12 hours. After this levels will start to decrease and its effects will wear off. It will take up to 3 days before Vyvanse is cleared completely from your system. How long Vyvanse will work depends on factors such as your age, weight, or other medications you may be taking. If you suddenly stop taking Vyvanse you may get withdrawal symptoms (also known as the Vyvanse crash) such as anxiety, irritability, and fatigue.

Treatment for ADHD is commonly arranged by a specialist in the psychiatry department. You should always consult your healthcare provider when starting, stopping, or changing your dose.

What doses of Vyvanse are available?

Vyvanse is available in:

  • Capsule form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg
  • Chewable tablet form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg

To make swallowing easier, open the capsule and sprinkle the medicine into a glass of water or orange juice, or mix it with yogurt. Once the medicine has dissolved, drink or eat the mixture right away.

For additional safety information, read the full prescribing information and medication guide. Always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Vyvanse side effects

The most common side effects of Vyvanse in children, adolescents, and/or adults with ADHD are:

  • Anorexia
  • Anxiety
  • Dizziness, nausea
  • Blurred vision
  • Dry mouth
  • Irritability
  • Insomnia
  • Upper abdominal pain, stomach pain, vomiting, loss of appetite, decreased weight, diarrhea, constipation
  • Motor tics (repeated muscle movements)
  • Increased heart rate

In rare instances, Vyvanse can cause more serious side effects. These can include:

  • Serious cardiovascular reactions e.g. chest pain
  • Sudden death has been reported with CNS stimulant treatment at recommended doses in pediatric patients with structural heart defects or other serious heart problems
  • Sudden death, stroke, and heart attacks in adults
  • High blood pressure and increase in heart rate
  • Suppression of growth – monitor height and weight in pediatric patients
  • Circulation problems, such as skin color changes, a cold feeling including Raynaud’s phenomenon
  • Serotonin syndrome – an increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations
  • New or worsening psychosis, bipolar disorder, or mental health issues
  • Withdrawal symptoms if you suddenly stop using this medication – severe tiredness, sleep problems, mental/mood changes such as depression
  • Severe allergic reactions e.g. hives, shortness of breath

Your doctor will assess the benefits of using Vyvanse against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Vyvanse to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What are Vyvanse’s drug interactions?

Vyvanse can interact with other medications, including prescription drugs. In some instances, this can change how it and other medications work. It can even increase the likelihood and severity of some side effects. Medications that are known or thought to interact with Vyvanse include:

  • Monoamine oxidase inhibitors, MAOIs, (methylene blue, phenelzine, or selegiline)
  • Tricyclic antidepressants (desipramine or protriptyline)
  • Medications that affect your serotonin system (SSRI or SNRI antidepressants, triptans, fentanyl, or St. John’s Wort)

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How to avoid Vyvanse side effects

While completely avoiding Vyvanse side effects may not be possible, there are some things you can do to reduce their severity:

1. Stick to the recommended dosage

Take your prescribed Vyvanse dosage that has been recommended by your healthcare professional at the same time every day to prevent you from forgetting your dose. Taking your medication consistently will make a big difference in how well Vyvanse works for you.

ADHD medications can be very effective when you find the right dosage. A good measure is to track your impulse control on various doses to monitor how you are reacting to the dose.

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Refer to the medication guide for more drug information.

2. Store Vyvanse correctly

Vyvanse should be stored at room temperature in a dry place in its original container. Knowing how to properly store your medication is important to make sure it remains as effective as possible. Taking expired or improperly stored medication could result in the medication not working properly and may even cause unwanted side effects. It’s also important to leave the drying agent that comes in the bottle inside of the bottle to prevent excess moisture from affecting the medication. The bottle should be closed tightly.

3. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Vyvanse will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Vyvanse and help manage any possible side effects.

4. Pay attention to your body

Paying attention to how your body feels when taking Vyvanse is important. Talk to your doctor straight away if you start to experience any side effects of Vyvanse when taking it.

If you find it more helpful ask family and friends for an honest opinion on improvement or deterioration in your focus, concentration, and overall condition when taking Vyvanse.

5. Seek help

Work with a mental health professional to help you manage your problems and how you feel, think, and act. This will in turn help you manage your symptoms and side effects better. Simple steps such as leaving early for appointments to avoid the worry of arriving late or using a calendar to plan your week ahead are useful ways to manage your ADHD.

Eliquis side effects and how to avoid them

Eliquis can cause adverse reactions. The more common side effects tend to be mild bleeding issues such as nosebleeds and you may also bruise more easily. Learn more about the most common Eliquis side effects and how to avoid them.

What is Eliquis?

Eliquis is an FDA-approved brand-name drug. It is an anticoagulant, a type of drug that stops blood clotting (from a liquid to a thick gel).

Eliquis is indicated for the following conditions:

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib, or irregular heartbeat known as an arrhythmia)
  • Prevent deep vein thrombosis (DVT) in the legs and pulmonary embolism (PE) in the lungs of patients who have had hip replacement or knee replacement surgery
  • Treatment of deep vein thrombosis (DVT) in the legs
  • Treatment of pulmonary embolism (PE) in the lungs
  • Reduce the risk of recurrent DVT and PE

Eliquis (apixaban) is not recommended for patients with artificial heart valves.

Blood clotting is a normal process that happens when you’re injured. If you cut yourself, a clot forms to seal the cut to stop you from losing any more blood. But sometimes blood can clot inside your body where it shouldn’t, and this can cause problems. Clots can block the flow of blood, starve parts of the body of oxygen, and damage tissues. Depending on where blood clots form, they can cause deep vein thrombosis, heart attacks, or strokes. Sometimes Eliquis is called a blood thinner, as it helps to lower the chances of blood clots forming.

More information on what is Eliquis

How does Eliquis work?

The active ingredient in Eliquis is an anticoagulant called apixaban. As blood clots, it goes through a process of chemical reactions that turn it from a liquid into a thick gel. An enzyme called factor Xa is an important part of this process. The active ingredient apixaban attaches itself to factor Xa to stop it from working, reducing the likelihood of blood clots forming.

What doses of Eliquis are available?

Eliquis is available in the following doses: 2.5 mg tablets and 5 mg tablets.

The recommended dose of Eliquis is 5 mg orally twice daily. For patients 80 years of age or older, weighing 60 kg or less, or having serum creatinine equal to or above 1.5 mg/dL, the recommended dose is 2.5 mg orally twice daily. Eliquis starts working within 3 to 4 hours after you take your first dose. Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition. There is a higher risk of blood clots or a stroke if Eliquis (apixaban) is stopped too soon. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose.

Eliquis and bleeding

Your blood forms clots to plug cuts and injuries, stopping you from bleeding. Because Eliquis reduces blood clots, it can increase your risk of bleeding, which can be serious, or even fatal.

You should avoid taking other medications that increase your chances of bleeding with Eliqiuis. These include aspirin and other antiplatelet agents, other anticoagulants, heparin, selective serotonin reuptake inhibitors (SSRIs), antidepressants, serotonin-norepinephrine reuptake inhibitors (SNRIs), and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen.

If you’re taking Eliquis and you begin to bleed or you experience symptoms of blood loss, seek urgent medical attention.

Side effects of Eliquis

What are the most common side effects of Eliquis?

The most common side effects of Eliquis are related to bleeding, such as

  • Nosebleeds
  • Bleeding gums
  • Heavier menstrual bleeding
  • Unexpected vaginal bleeding

What are the bad side effects of Eliquis?

Serious side effects that can sometimes occur when taking Eliquis can include:

  • Serious allergic reactions to the medication. Symptoms include hives, chest pain, and trouble breathing
  • Bleeding in your brain and spinal column
  • Bleeding in your lungs
  • Bleeding into a muscle
  • Unusual bleeding
  • Vomiting blood that looks like coffee grounds
  • Tarry stools

The increased risk of bleeding problems may on occasion turn into major bleeding, causing life-threatening results. Eliquis can have side effects, although not everyone will experience them, or have the same ones. Most side effects caused by Eliquis are related to increased bleeding, as the medication prevents clotting. Inform your doctor if you are on Eliquis before you have any medical or dental procedures or surgery.

This isn’t a comprehensive list of all the side effects Eliquis can cause. Side effects depend on the dose you’re taking and the condition you’re taking Eliquis for. You can find more details on the side effects in the patient leaflet that comes with your medication. If you have any concerns about Eliquis’ side effects, talk to your physician or a pharmacist for medical advice.

Stopping Eliquis side effects

Discontinuing treatment with Eliquis will normally stop the side effects you are experiencing. However, if you need to reverse the effects of Eliquis you may be prescribed an antidote such as Andexanet alfa (Andexxa) by your doctor. It is important to know that stopping Eliquis treatment may actually increase the risk of side effects. Speak to your doctor for medical advice if you plan to stop your Eliquis treatment.

Eliquis and drug interactions

Eliquis and other medications can interact with each other. These drug interactions can change how the drugs work and can make side effects more likely. Don’t take Eliquis if you’re taking any other medications to prevent blood clotting, like Coumadin (warfarin), Plavix (clopidogrel), Lovenox (enoxaparin), and Xarelto (rivaroxaban). Talk to your physician if you’re taking any of the following:

  • An antifungal medicine e.g. itraconazole, ketoconazole
  • Antiviral medicines for HIV/AIDS e.g. ritonavir
  • Anti-inflammatory medicines e.g. naproxen
  • Pain medications
  • Medicines for high blood pressure or heart problems
  • Antidepressants
  • Medicines to prevent epilepsy or seizures e.g. carbamazepine, phenytoin
  • Medicines to treat tuberculosis
  • St John’s Wort

Before you take Eliquis tell your doctor if you:

  • Have kidney or liver problems
  • Have antiphospholipid syndrome 3
  • Have any other medical conditions
  • Have ever had bleeding problems
  • Have had a spinal puncture
  • Have had an epidural catheter, or if you are within 5 hours of its removal. It should not be taken by people receiving pain medications through an epidural catheter
  • Are pregnant or plan to become pregnant or are breastfeeding

Make sure you tell your prescribing physician about all medications you’re taking, including any over-the-counter drugs or supplements.

How to take Eliquis

Eliquis comes as a tablet that is taken orally, usually swallowed with water. It’s typically taken once a day, at the same time each day. Eliquis can be taken with or without food.

If you have difficulty swallowing tablets, Eliquis can be crushed into a powder. This powder can be mixed into water, 5% dextrose in water, apple juice, or into apple puree. Talk to your doctor if you need to take Eliquis in this way.

Your Eliquis dosage will be decided upon by your physician. This will vary depending on the condition you’re taking it for and your medical history. Always take your Eliquis as directed by the prescribing medical professional.

If you take too much Eliquis you may have an increased risk of bleeding. You must seek medical attention immediately if this happens. Take your Eliquis packaging with you, even if there are no tablets left.

If you forget to take your Eliquis, take your normal dose as soon as you remember. Take your next dose at the usual time, then continue as normal.

Don’t stop taking Eliquis without talking to your physician. Your risk of developing a blood clot could be higher if you stop your treatment too early.

How to avoid Eliquis side effects

While completely avoiding Eliquis side effects may not be possible, there are some things you can do to reduce their severity:

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional. It’s typically taken once a day, at the same time each day. Eliquis can be taken with or without food. Sticking to this timing and taking your medication consistently will make a big difference in how well Eliquis works for you.

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Refer to the medication guide for more drug information.

2. Store Eliquis correctly

Eliquis should be stored at room temperature in a dry place in its original container. Knowing how to properly store your medication is important to make sure it remains as effective as possible. Taking expired or improperly stored medication could result in the medication not working properly and may even cause unwanted side effects. It’s also important to leave the drying agent that comes in the bottle inside of the bottle to prevent excess moisture from affecting the medication. The bottle should be closed tightly.

3. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Elquis will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Eliquis that may increase possible side effects.

4. Pay attention to your body

Paying attention to how your body feels when taking Eliquis is important, taking particular attention to bleeding. Try to avoid sports or activities that may cause injury to you. Talk to your doctor straight away if you start to experience any side effects of Eliquis when taking it.

Linzess side effects and how to avoid them

Linzess can cause adverse reactions. The more common side effects tend to be mild and restricted to the bowels as the medication is not absorbed easily into your blood. Learn more about the most common Linzess side effects and how to avoid them.

What is Linzess?

Linzess (linaclotide) is the brand name of a prescription medication manufactured by AbbVie and Ironwood Pharmaceuticals. It is used to treat constipation but it is not a laxative. Most often it’s prescribed for:

  • Chronic idiopathic constipation (CIC)
  • Irritable bowel syndrome with constipation (IBSC)

Linzess helps with constipation by reducing any pain in the bowels and by causing more liquid to enter your bowels from your body. This softens your stools and makes them easier to pass. The medication is swallowed as a capsule when you have an empty stomach. It’s usually taken once a day, before your first meal.

If someone is constipated, they find it difficult to pass a stool. Their stools may be hard and dry, and they may feel bloated and in pain. This can lead to the development of hemorrhoids, anal fissures, and fecal impaction. Chronic constipation is constipation that lasts several weeks or longer. Irritable bowel syndrome (IBS) is a group of conditions that can cause abdominal pain and bowel problems, including constipation. You should not use linaclotide if you have a blockage in your intestines.

More information on what is Linzess

What doses of Linzess are available?

Linzess is available in capsule form, in the following doses: 72 mcg, 145 mcg, and 290 mcg.

The recommended Linzess dosage in adults will depend on the condition being treated. Linzess is not recommended for pediatric patients younger than 18 years of age. You should take this medication on an empty stomach at least 30 minutes before your first meal of the day.

Do not crush or chew the capsule or the contents of the capsule. If you have problems swallowing capsules whole or have a nasogastric or gastrostomy tube, refer to the full prescribing information for how to open the capsule, and how to take it with applesauce or water.

Linzess active ingredients

Linzess belongs to a group of medications called guanylate cyclase-C agonists. The active ingredient in Linzess is called linaclotide. Linaclotide isn’t easily absorbed by your body, but this is a good thing. It means the drug reaches your bowels where it can do its work, rather than being absorbed and dispersed around your body.

When linaclotide reaches your bowels it binds to the cells in the walls of your gut to stimulate bowel movements. Once there, it increases the amount of water and other fluids that pass from your body into your bowels, softening your stools. It does this by increasing the secretion of chloride and water. It also decreases the activity of sensory cells in your bowels, reducing any pain felt.

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Linzess side effects

From clinical trial data, typical side effects can include:

  • Gastrointestinal side effects such as diarrhea, bloating (abdominal distension), stomach pain, flatulence, dizziness
  • Infection side effects such as sinusitis, and upper respiratory tract infection

Less common side effects include:

  • Viral gastroenteritis
  • Allergic reactions e.g. hives
  • Severe diarrhea
  • Severe stomach pain

Although diarrhea is a common side effect of Linzess, it should pass. If it lasts for more than seven days, and you feel lightheaded, dizzy, or faint (signs of dehydration), or if your diarrhea is severe, stop taking the medication and contact your physician. Diarrhea caused by Linzess can stop other medications from working properly, especially medicines with exact doses. If side effects persist you may be offered an alternative drug such as Amitiza.

Prolonged diarrhea could stop birth control medication from working, so you should use other methods of contraception when taking Linzess. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-FDA-1088).

How to avoid Linzess side effects

While completely avoiding Linzess side effects may not be possible, there are some things you can do to reduce their severity:

1. Stick to the recommended dosage

Take your prescribed dose that has been recommended by your healthcare professional every morning 30 minutes before your first meal of the day. Sticking to this timing and taking your medication consistently will make a big difference in how well Linzess works for you.

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Refer to the medication guide for more drug information.

2. Store Linzess correctly

Linzess should be stored at room temperature in a dry place in its original container. Knowing how to properly store your medication is important to make sure it remains as effective as possible. Taking expired or improperly stored medication could result in the medication not working properly and may even cause unwanted side effects. It’s also important to leave the drying agent that comes in the bottle inside of the bottle to prevent excess moisture from affecting the medication. The bottle should be closed tightly.

3. Discuss medical history

Discussing your medical history with your healthcare provider is important to help them understand how well Linzess will work for you. Give a complete list of all the prescription drugs, including over-the-counter meds, supplements, and medical conditions you may have. Talking with your doctor will allow them to pick up any drug interactions with Linzess that may increase possible side effects.

4. Pay attention to your body

Paying attention to how your body feels when taking Linzess is important. Talk to your doctor straight away if you start to experience any side effects of Linzess when taking it.

Comparing Xarelto alternatives: which other blood thinners can I take?

Direct oral anticoagulants (DOACs) are blood thinner prescription drugs that have a rapid onset of action and require no blood monitoring. Xarelto is an FDA-approved drug in this category but Xarelto alternatives are available if you and your healthcare professional agree it’s needed. Let’s take a look at these.

What is Xarelto?

Xarelto contains the active ingredient rivaroxaban. It is a direct oral anticoagulant and works by blocking factor Xa in the blood clotting process.

It comes in tablet form and is taken by mouth. Xarelto is available in four strengths: 2.5 mg, 10 mg, 15 mg, and 20 mg. Your dosage will vary based on what you are being treated for. Xarelto is manufactured by Janssen Pharmaceuticals.

What conditions are treated with Xarelto?

Xarelto is indicated for the following conditions:

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib, or irregular heartbeat)
  • Prevent deep vein thrombosis (DVT) in the legs and pulmonary embolism (PE) in the lungs of patients who have had hip or knee replacement surgery
  • Treatment of deep vein thrombosis (DVT)
  • Treatment of pulmonary embolism (PE)
  • Reduce the risk of blood clots happening again in people who continue to be at risk for DVT or PE after receiving treatment for blood clots for at least 6 months
  • Prevention of DVT, which may lead to PE in patients undergoing knee or hip replacement surgery
  • Prevention of blood clots in certain people hospitalized for an acute illness and after discharge, who are at risk of getting blood clots due to the loss of or reduced ability to move around, and other risks for getting blood clots, and who do not have a high risk of bleeding

Xarelto can also be used with aspirin to:

  • Lower the risk of dangerous cardiovascular events such as death, heart attack, and stroke in patients with chronic coronary artery disease (CAD) or peripheral artery disease (PAD)
  • Reduce the risk of a serious reduction in blood flow to the legs, stroke, major amputation, and heart problems in patients with PAD (peripheral artery disease, a condition where the blood flow to the legs is reduced). Xarelto is not for use in people with artificial heart valves

What are the common side effects of blood thinners?

Anticoagulant medications can cause an increased risk of bleeding. The most common side effect of blood thinners include symptoms such as:

  • Nose bleeds
  • Heavier than normal menstrual bleeding
  • Gastrointestinal bleeding
  • A cut that does not stop bleeding
  • Bruising
  • Increased bleeding risk

What are the alternative meds to Xarelto?

Eliquis

Eliquis contains the active ingredient apixaban. It is a direct oral anticoagulant that works by blocking factor Xa just like Xarelto. Factor Xa produces thrombin, a fundamental component in the clotting process. By blocking factor Xa, Eliquis can reduce the production of clots.

Eliquis is available in two strengths: 2.5 mg and 5 mg. Your dosage will vary based on what you are being treated for. Eliquis is manufactured by Bristol-Myers Squibb.

Eliquis is indicated for the following conditions:

  • Reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation (AFib, or irregular heartbeat known as an arrhythmia)
  • Prevent deep vein thrombosis (DVT) in the legs and pulmonary embolism (PE) in the lungs of patients who have had hip or knee replacement surgery
  • Treatment of deep vein thrombosis (DVT) in the legs
  • Treatment of pulmonary embolism (PE) in the lungs
  • Reduce the risk of recurrent DVT and PE

Pradaxa

Pradaxa is a blood thinner (anticoagulant) medication prescribed to adults to lower the chance of blood clots forming. Specifically, it’s used to:

  • Lower the risk of blood clots that can cause strokes in people who have a medical condition called atrial fibrillation
  • To treat and prevent blood clots forming in veins in the legs (deep vein thrombosis) or lungs (pulmonary embolism)
  • To help lower the risk of blood clots forming in veins in the legs (deep vein thrombosis) or lungs (pulmonary embolism) of people who’ve had hip replacement surgery

Pradaxa can be taken to treat existing blood clots and to reduce the chances of blood clots forming. It works by interrupting a step in the blood clotting process. You take Pradaxa as an oral capsule, usually twice a day.

The active ingredient in Pradaxa is called dabigatran. It’s a blood thinner (anticoagulant) that stops your blood from clotting. Your blood clots by going through a complex chemical reaction with multiple steps. Some steps of this reaction use enzymes to help change your blood from a liquid to a gel. One of these enzymes is called thrombin.

Dabigatran works by blocking thrombin. When you swallow Pradaxa, molecules of dabigatran are absorbed in your blood, where they bind to thrombin. This stops thrombin from working and blocks a step of the clotting process.

Brilinta

Brilinta is a medication taken to reduce the risk of heart attacks, strokes, and death caused by blood clots. It’s prescribed to adults who:

  • Have previously had a heart attack
  • Have coronary artery disease (CAD) and who are at a high risk of having a heart attack or a stroke
  • Have acute coronary syndrome (ACS)
  • Have ACS and who have been treated with a stent

If you have CAD, ACS, or have a stent due to ACS, you may be at a greater risk of blood clots forming, and your doctor may prescribe Brilinta to you. Brilinta helps to stop your blood clotting, reducing your risk of a heart attack or stroke.

You take Brilinta as a tablet, that you swallow with water. Your doctor will decide upon your dose and how often you take your Brilinta.

The active ingredient in Brilinta is called ticagrelor, which reduces the risk of your blood clotting and causing a heart attack or a stroke. It works on the platelets in your blood, which are the substances that cause your blood to thicken and clot. Ticagrelor attaches to areas on the surface of your platelets called receptors. This stops them from being able to stick together and start the process that causes clotting.

Warfarin

Warfarin (Coumadin) is the oldest and most widely used blood thinner and requires regular blood tests to measure how fast your blood clots using the INR (International Normalized Ratio).

Warfarin works by decreasing the clotting ability of the blood. It is used to prevent blood clots from forming or growing in size in your blood and blood vessels.

It is prescribed for people:

  • With certain types of irregular heartbeat
  • With prosthetic (replacement or mechanical) heart valves
  • Who have suffered a life-threatening heart attack
  • To treat or prevent venous thrombosis
  • To treat or prevent pulmonary embolism

Plavix

Plavix is a brand-name prescription drug containing the active ingredient clopidogrel. Clopidogrel is a platelet inhibitor used to prevent cardiovascular events such as heart attack and stroke.

Plavix can be given to people who:

  • Have acute coronary syndrome (ACS)
  • Have had a heart attack or stroke in the past
  • Have peripheral artery disease (PAD)

Plavix is given in combination with daily aspirin.

Savaysa

Savaysa is a brand-name drug of edoxaban, an anticoagulant that works by blocking certain clotting proteins in your blood. Edoxaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation). It is also used to treat certain blood clots e.g. deep vein thrombosis or pulmonary embolus.

Is there a cheaper alternative to Xarelto?

Currently, Xarelto generic is not available in the United States. However, there are several cheaper alternatives to Xarelto available. Warfarin, known by the brand names Coumadin and Jantoven, is a comparable generic drug that can cost as little as $5 per month. Speak with your healthcare provider to find out if Warfarin is medically appropriate for you.

Final word

Some medicines can cause drug interactions with blood-thinning drugs and cause serious problems. Tell your healthcare provider about all the medicines you take. This includes over-the-counter medicines, supplements like vitamin K, minerals, or herbal supplements. Medical advice from a cardiologist or other healthcare professional must be taken when changing medications from one drug to another.

What is a biologic drug? Biologic vs Biosimilar

Biologic drugs provide more treatment options for patients who have serious health conditions or who have previously had no available treatment options. Biologics are produced from living organisms but just like conventional drugs, all biologic drugs and biosimilars must be approved by the Food and Drug Administration (FDA) for safety and effectiveness. The most well know biologic is the brand name drug Humira, active ingredient adalimumab, used for rheumatoid arthritis, psoriatic arthritis, psoriasis, ulcerative colitis, and ankylosing spondylitis. But what is a biologic drug? Let’s answer this question for you and find out more.

What is a biologic drug?

Biologics or biological medicines originate from living cells, such as humans, animals, or microorganisms using biotechnology, whereas chemically derived drugs are created in laboratories. Chemically derived or traditional drugs are described as small molecule drugs. Biologic drugs on the other hand are much larger in size, containing more complex molecules, making them challenging and costly to make. The growth of the cells in biologic medications can take several weeks and requires constant monitoring. The protein that makes up the drug is extracted and purified until the final biologic drug is obtained.

Biological products include a wide range of products including:

  • Vaccines
  • Blood components
  • Gene therapy
  • Tissues
  • Proteins, like monoclonal antibodies and cell signaling proteins

The manufacturing process of biological drugs makes it is impossible to guarantee that each batch of a biologic drug will be identical to the last, which means every dose of a biologic medicine has slight variations.

What conditions can biological medications treat?

Biologic therapies can be used to treat a number of different conditions such as:

Examples of a biologic and biosimilar drugs

Original biologic name (reference product)Biosimilar nameManufacturerFDA approval date
Neupogen (filgrastim)
Manufacturer: Amgen
FDA approval date: 2002
Zarxio
Nivestym
Releuko
Sandoz
Pfizer
2015
2018
Remicade (infliximab)
Manufacturer: Janssen
FDA approval date: 1998
Inflectra
Renflexis
Ixifi
Avsola
Calltrion
Samsung Bioepis
Pfizer
Amgen
2016
2017
2017
2019
Enbrel (etanercept)
Manufacturer: Amgen
FDA approval date: 1998
Erelzi
Eticovo
Sandoz
Samsung Bioepis
2016
2019
Humira (adalimumab)
Manufacturer: Abbvie
FDA approval date: 2002
Amjevita
Cyltezo
Hyrimoz
Hadlima
Abrilada
Hulio
Yusimry
Amgen
Boehringer Ingelheim
Sandoz
Samsung Bioepis
Pfizer
BGP Pharma ULC (Viatris)
Coherus BioSciences, Inc.
2016
2017
2018
2019
2019
2020
2021
Avastin (bevacizumab)
Manufacturer: Genentech
FDA approva datel: 2004
Mvasi
Zirabev
Alymsys
Amgen
Pfizer
Amneal
2017
2019
2022
Herceptin (trastuzumab)
Manufacturer: Roche
FDA approval date: 1998
Ogivri
Herzuma
Ontruzant
Trazimera
Kanjinti
Mylan and Biocons
Celltrion
Samsung Bioepis
Pfizer
Amgen
2017
2018
2019
2019
2019
Neulasta (pegfilgrastim)
Manufacturer: Amgen
FDA approval date: 2002
Fulphila
Udenyca
Ziextenzo
Nyvepria
Mylan and Biocons
Coherus Biosciences
Sandoz
Pfizer
2018
2018
2019
2020
Rituxan (rituximab)
Manufacturer: Genentech and Biogen
FDA approval date: 1997
Truxima
Ruxience
Riabni
Celltrion
Pfizer
Amgen
2018
2019
2020
Lucentis (ranibizumab)
Manufacturer date: Genentech
FDA approval: 2006
ByoovizSamsung Bioepis2021
Lantus (insulin glargine-yfgn)
Manufacturer date: Sanofi
FDA approval: 2000
Rezvoglar
Semglee
Eli Lilly
Mylan
2021
2021
Retacrit (epoetin alfa-epbx)
Manufacturer date: Pfizer
FDA approval: 2018
EpogenAmgen2021

According to figures from Statista, the top 10 best-selling biologics worldwide in 2020 were:

  • Humira (adalimumab) – used to treat rheumatoid arthritis, psoriatic arthritis, psoriasis, ulcerative colitis, and ankylosing spondylitis
  • Keytruda (pembrolizumab) – used to treat a range of cancers
  • Eylea (aflibercept) – a prescription medication given to adults to treat a range of eye conditions
  • Dupixent (dupilumab) – an injectable medicine used to reduce inflammation
  • Opdivo (nivolumab) – used to treat melanoma skin cancer
  • Avastin (bevacizumab) – a cancer medication that stops tumors from creating their own blood supply, starving them of blood, oxygen, and nutrients
  • Enbrel (etanercept) – used to treat autoimmune conditions by reducing inflammation
  • Rituxan (rituximab) – a prescription medication used to treat some types of cancer and certain autoimmune diseases
  • Herceptin (trastuzumab) – used to treat cancers called HER2 (human epidermal growth factor receptor 2) overexpressing cancers
  • Remicade (infliximab) – a medication used to treat specific autoimmune diseases, and some similar diseases

What are the side effects of biologic drugs?

Common side effects of biologic drugs include:

  • Injection site reactions – redness, itching, swelling, pain
  • Nausea, upset stomach
  • Headaches – more common in people who use biologic drugs
  • Infection – biologic meds raise your risk of infection because they weaken your immune system
  • Reactivation of infections – biologic medicines can cause the return of conditions like hepatitis B or tuberculosis (TB) if you have had them before

Less Common Side effects of biologics include:

  • Central nervous system issues – sudden vision problems, numbness, or tingling
  • Heart problems
  • Shortness of breath or sudden heart failure is possible
  • Some studies have suggested that biologic medicines may slightly raise your risk of certain types of cancer
  • Liver problems – symptoms of liver issues include yellowing of the skin or eyes
  • New joint pain – even though biologics are used to treat arthritis, they can sometimes cause new joint pain

Serious reactions are rare but may include:

  • Trouble breathing
  • A severe allergic reaction
  • Chest pain or tightness
  • Fever or chills
  • High or low blood pressure
  • Swelling of the face and hands

Your health care provider can share more information about biologics and if they’re the best treatment for you.

What is a biosimilar drug?

All biosimilar drugs are prescription drugs that can only be obtained by a health care professional. These drugs are very similar to their reference biologic. This is why biosimilar drugs are often confused with generic drugs. Let us clear up this confusion and dive into the topic of biosimilars and provide you with some useful information on what a biosimilar product is, examples of drugs in this category, and more.

What is a biosimilar drug?

A biosimilar drug is a biological product that is very similar to another biological product known as the reference biologic (the original biologic). The reference biological medicine is the first brand to market. eg. the brand name drug Humira manufactured by Abbvie is the reference biologic and Amjevita is its biosimilar manufactured by Amgen.

A biosimilar has no clinically meaningful differences in safety, purity, and effectiveness from an existing FDA-approved reference product.

Biological medicines originate from living cells, such as humans, animals, or microorganisms whereas chemically derived drugs are created in laboratories. Chemically derived or traditional drugs are described as small molecules, biologic drugs on the other hand are much larger in size, and have more complex structures making them challenging and costly to make.

Biological products can include a wide range of products including:

  • Vaccines
  • Blood components
  • Gene therapy
  • Tissues
  • Proteins, like monoclonal antibodies and cell signaling proteins

What makes a drug biosimilar?

Biosimilar medicines have certain characteristics:

  • Highly similar to the reference product
  • No difference in effectiveness to the reference product
  • Minor differences to the reference product within strict limits
  • Approved according to the same FDA (U.S. Food and Drug Administration) standards of quality safety and efficacy

In order to make biologic drugs more affordable and widely available to more people, the Biologics Price Competition and Innovation Act of 2009 was passed allowing the FDA to quicken the approval process for biosimilar drugs by using clinical trial evidence already gathered from the reference products.

Examples of medical conditions that use biological drugs for treatment:

Are biosimilars the same as generics?

No. Biosimilars and generics are different for a number of reasons:

  • Generic drugs are identical to the original brand name drug in chemical composition but biosimilar drugs are highly similar
  • Generic products are easily interchangeable with a brand product but biosimilars need special approval to do so
  • Generic drugs are copies of synthetic drugs, while biosimilars use living sources
  • Generic drugs are small molecules whereas biosimilars are large, complex molecules

One similarity they do share is they aim to provide cost-saving treatment options to patients.

What are the biosimilars to Neupogen?

The first biosimilar drug approved by the FDA for Neupogen (filgrastim) was Zarxio (filgrastim-sndz) in 2015. Filgrastim is a granulocyte colony-stimulating factor medicine that increases the number of neutrophil white blood cells your body produces. When you take Neupogen, the filgrastim it contains is absorbed into your bone marrow where it triggers the processes that cause your bone marrow to produce neutrophil white blood cells.

Zarxio is highly similar to the brand biologic and has no clinically meaningful differences with Neupogen in terms of safety, purity, and potency. In July 2018, FDA approval was granted to Pfizer’s Nivestym (filgrastim-aafi), another biosimilar to Amgen’s Neupogen.

What are the biosimilars to Remicade?

Remicade was originally approved in 1998. The first biosimilar to Remicade was approved by the FDA in 2016, made by Pfizer, and called Inflectra (infliximab-dyyb). It is used for the same indications as Remicade.

Other biosimilars to Remicade include:

  • Renflexis (infliximab-abda)
  • Ixifi (infliximab-qbtx)
  • Avsola (infliximab-axxq)

Remicade and Inflectra are prescribed for the same indications, including:

  • Rheumatoid arthritis
  • Crohn’s disease
  • Ankylosing spondylitis
  • Ulcerative colitis
  • Psoriatic arthritis
  • Plaque psoriasis.

What are the biosimilars to Enbrel?

The active ingredient in Enbrel is called etanercept. It helps to treat certain autoimmune diseases by reducing the inflammation they cause.

Erelzi (etanercept-szzs), was FDA-approved in 2016 as Enbrel’s first biosimilar, followed by a second biosimilar Eticovo in 2019.

Erelzi is used for the same five indications as Enbrel:

  • Rheumatoid arthritis
  • Polyarticular juvenile idiopathic arthritis
  • Psoriatic arthritis
  • Ankylosing spondylitis
  • Plaque psoriasis

What are biosimilars to Humira?

Humira was launched to market in December 2002 by Abbvie. It is a medication used to treat autoimmune diseases like rheumatoid arthritis, and similar inflammatory diseases like Crohn’s disease. Humira is injected under the skin. It can be easily taken at home using a pre-filled self-injecting syringe or pen device.

The first biosimilar to Humira was approved in 2016, called Amjevita (adalimumab-atto), a monoclonal antibody that has the same amino acid sequence as adalimumab. It is currently available in Europe only and will be launched in the US alongside the other biosimilars below in 2023.

Other Humira biosimilars are:

  • Hulio (adalimumab-fkjp)
  • Cyltezo (adalimumab-adbm)
  • Hyrimoz (adalimumab-adaz)
  • Abrilada (adalimumab-afzb)
  • Hadlima (adalimumab-bwwd

What are the biosimilars for cancer treatment?

In 2017, the first U.S. biosimilar for any cancer indication was approved by the FDA, Mvasi (bevacizumab-awwb) which is a biosimilar to Avastin (bevacizumab), followed by Zirabev (bevacizumab-bvzr) in 2019.

Herceptin another cancer treatment has five biosimilars that have been approved by the FDA:

  • Ogivri (trastuzumab-dkst) approved in Dec 2017
  • Herzuma (trastuzumab-pkrb) approved in Dec 2018
  • Ontruzant (trastuzumab-dttb) was approved in Jan 2019
  • Trazimera (trastuzumab-qyyp) approved March 2019
  • Kanjinti (trastuzumab-anns) approved June 2019

This medication helps by blocking human epidermal growth factor receptor 2, to prevent it from being stimulated and stopping the cancerous cells from multiplying and spreading. It may also help your immune system to kill your cancerous cells.

What are the biosimilars of Rituxan?

For cancers like non-Hodgkin’s lymphoma, Rituximab can reduce the number of cancerous lymphocytes you have. For chronic lymphocytic leukemia, rituximab can prevent the harmful buildup of lymphocytes. In the case of autoimmune diseases, rituximab can cause a fall in your lymphocyte levels. This reduces the amount of inflammation your lymphocyte white blood cells can trigger.

  • In 2018, the FDA approved Truxima (rituximab-abbs) injection from Celltrion as the first biosimilar to Rituxan (rituximab). Truxima is also the first US biosimilar overall to be approved for the treatment of non-Hodgkin’s lymphoma
  • The second biosimilar to Rituxan was approved in 2019 called Ruxience (rituximab-pvvr)
  • The third biosimilar Riabni (rituximab-arrx) was approved in 2020

The table below shows various biological medications and their biosimilars.

Can biosimilars be substituted for a reference biologic?

Your healthcare provider will be knowledgeable in which biological products are interchangeable. Once approved, a biosimilar needs to have special approval to be considered interchangeable with its brand name biologic drug.

For example, in 2021, the FDA granted Cyltezo an interchangeable product with Humira. Also in 2021, Semglee (insulin glargine) was approved as an interchangeable biologic with Lantus.

What are triglycerides?

Have you recently been told you have raised triglyceride levels but have many unanswered questions? Triglycerides are a measure of heart health and having a high level of triglycerides in your blood can increase your risk of heart disease. The first steps in treatment to lower triglyceride levels include eating a healthy diet and an increase in exercise, but if this is not enough medication options are available. Read on to learn more about triglycerides, including what causes high triglyceride levels and how to lower them.

What are triglycerides?

Triglycerides can be described as a type of fat scientifically known as a lipid found in your blood.

How are they different from cholesterol?

Triglycerides and cholesterol are different types of lipids that circulate in your blood:

  • Triglycerides are our main source of energy and store of calories for use when needed
  • Cholesterol is used to make cells in the body and certain hormones

How do triglycerides get into the blood?

Triglycerides are in some foods that we eat, such as meat, dairy products, cooking oils refined grains, sugary foods, and drinks. These foods go through your digestive system and triglycerides are absorbed by your intestines.

From there they are packaged together with proteins to form a chylomicron (lipoprotein), which is used as a vehicle to transport triglycerides to our tissues to be used for energy immediately or stored for later use in your fat cells.

Eating more calories than you burn and consuming high amounts of carbohydrate foods may lead to high triglyceride levels (hypertriglyceridemia).

What’s considered normal?

The National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III) guidelines divide triglyceride levels into four different classes:

  • Normal

Less than 150 milligrams per deciliter (mg/dL), or less than 1.7 millimoles per liter (mmol/L)

  • Borderline high

150 to 199 mg/dL (1.8 to 2.2 mmol/L)

  • High

200 to 499 mg/dL (2.3 to 5.6 mmol/L)

  • Very high

500 mg/dL or above (5.7 mmol/L or above)

Your doctor will carry out a simple blood test to determine your triglyceride level. This is normally part of a comprehensive cholesterol test known as a lipid panel that will give a complete picture of your lipid profile. A lipid panel will measure your low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and total cholesterol level. This test must be carried out in a fasted state.

What do high triglycerides do to your body?

High triglycerides can build up and clog up your blood vessels causing them damage, contributing to a build-up fatty plaques known as atherosclerosis. Blood flow is restricted through these narrowed blood vessels increasing the risk of stroke, heart attack, and heart disease. Inflammation of the pancreas (pancreatitis) can also occur with extremely high triglyceride levels.

High triglycerides can also be a sign of:

  • Metabolic syndrome – a condition when high blood pressure, obesity, and high blood sugar occur together, increasing your risk of heart disease
  • Hypothyroidism (low levels of thyroid)
  • Type 2 diabetes

High triglycerides can sometimes occur as a side effect of taking certain medications, such as:

  • Diuretics
  • Estrogen and progestin
  • Retinoids
  • Steroids
  • Beta-blockers

What is the best way to reduce triglycerides?

The American Heart Association emphasizes a healthy lifestyle to reduce levels and keep them low:

  • Increase your physical activity

30 minutes of moderate-intensity physical activity on five or more days

  • Avoid sugar and simple carbohydrates

Foods that contain high amounts of simple sugars, especially fructose raise triglyceride levels. Try opting for whole grains carbohydrates such as oats, brown rice and multi-grain bread instead of white flour foods

  • Reduce calorie intake and lose weight

Extra calories are converted to triglycerides and stored as fat

  • Choose healthier fats

Cooking with olive oil and canola oil is a better choice. Instead of red meat, try fish high in omega-3 fatty acids such as mackerel or salmon. Avoid foods such as cakes, cookies, and frozen pizzas that contain trans fats. Keep dietary fat to 25-35% of the total diet.

Alcohol is calorific and contains sugar. Even small amounts of alcohol can lead to changes in triglyceride levels.

What about medication?

If healthy lifestyle changes have not reduced your triglyceride levels enough your healthcare provider may recommend drug treatment. These drugs work in different ways to lower high cholesterol. The following drugs are available:

Statins

Fibrates

Fibrates aren’t used if you have severe kidney or liver disease.

Fish oil

These products contain more-active fatty acids than many nonprescription supplements.

Niacin is also known as nicotinic acid

  • Niaspan
  • Niacor
  • Nicotinex

There are also combination products containing niacin and a statin available such as Simcor (niacin/simvastatin) for patients.

Medications are helpful to reduce blood triglyceride levels but ultimately healthy lifestyle changes are very important for long-term benefit.

What are blood thinners?

Blood thinner medications prevent blood from sticking together (coagulation) which increases the amount of time it takes for your blood to clot. You might be given this medication after you have a stroke or to help you avoid another stroke or if you have a heart problem.

This guide will give you basic information about the topic to kick start your discussion with your healthcare professional about treatment options. While taking these medications, there is always some risk of serious bleeding which is why you should always get individual medical advice to receive the most appropriate treatment.

What are blood thinners and how do they work?

When you get hurt, blood cells called platelets gather at the injury site and form a blood clot. Platelets are sticky, and they form clumps creating a plug. Clotting factors are also released from platelets that help form a mesh to form the plug to close the wound.

The clotting process is essential when you’re injured. Sometimes, however, a blood clot can appear in an artery that supplies your heart or brain with oxygen-rich blood. When a clot blocks blood flow to your heart, it can cause a heart attack. If it blocks the blood flow to your brain, it can cause a stroke. The use of blood thinners in this group of patients is common. Warfarin (Coumadin) is the oldest and most widely used blood thinner and requires regular blood tests to measure how fast your blood clots using the INR (International Normalized Ratio).

Doctors have the option of prescribing a number of different types of blood thinners from two main categories of medications – antiplatelet drugs or anticoagulant drugs, which work at different stages of the blood clot formation process:

Antiplatelet

Antiplatelets prevent blood platelets from clumping and forming clots. These drugs act mainly on receptors and proteins that normally receive chemical signals causing cells to bind, to achieve this effect.

Anticoagulants

Anticoagulant drugs work by blocking the clotting process by targeting clotting factors such as thrombin, fibrin, and vitamin K.

Why do people take blood thinners?

Blood-thinning medications are used in patients who are at risk of developing blood clots that could block a blood vessel and disturb the flow of blood around the body. You will most likely be prescribed this medication if you have:

Generally, these medical conditions can cause blood clots. You also have a greater risk of blood clots if you’re overweight, recently had surgery, or have an artificial heart valve.

What are the common side effects of blood thinners?

Anticoagulant medications can increase your risk of bleeding. The most common side effect of blood thinners include symptoms such as:

  • Nose bleeds
  • Heavier than normal menstrual bleeding
  • A cut that does not stop bleeding
  • Bruising

Some medicines can interact with blood thinners and cause serious problems. Tell your healthcare provider about all medicines you take. This includes over-the-counter medicines, supplements like vitamin K, minerals, or herbal supplements.

What are antidepressants?

Antidepressant drugs commonly treat major depressive disorder and work by adjusting or rebalancing various chemicals in the brain. However, we know depression is not only caused by this and the condition is more complex. There are many antidepressants available to you, which ones are there? What are the side effects? How do they work? Read on to find out about the basics.

What do antidepressants treat?

Antidepressant drugs are used to treat the symptoms of depression, it affects people in many different ways and symptoms vary from person to person. Symptoms can range from low mood, and losing enjoyment in things you enjoy, to severe depression where you have suicidal thoughts. Antidepressants can help manage the symptoms of depression. By working with a healthcare professional you can find the right combination of medications and therapy for you.

They can also be used to treat a number of other conditions, including:

  • Obsessive-compulsive disorder (OCD)
  • Anxiety disorder
  • ADHD
  • Chronic pain

How do antidepressants work?

Antidepressant medications generally work by balancing neurotransmitters such as:

  • Serotonin
  • Norepinephrine (also called noradrenaline)
  • Dopamine

These chemicals are involved in mood regulation therefore by rebalancing their levels in the brain symptoms of depression can be prevented from worsening.

While antidepressants can treat the symptoms of depression, they do not always address its causes. This is why they’re usually used in combination with talk therapy (psychotherapy) to treat more severe depression or other mental health conditions.

How effective are antidepressants?

It can take a number of weeks to begin seeing improvements in your symptoms. The effects of an antidepressant can take time to kick in and any side effects you may experience will take time to ease off or become manageable. Everyone will react differently to various antidepressants and you may need to try a few before finding one that suits you. Dosage changes and medication changes are possible when on antidepressants.

A systematic review published in The Lancet looked at 21 antidepressants and found that most antidepressants were more effective than placebo but also that some were more effective than others.

What are the different types of antidepressants?

There are several classes of antidepressants:

Selective serotonin reuptake inhibitors (SSRIs)

SSRIs are the most widely prescribed type of antidepressant. They are usually prescribed over other antidepressants, as they tend to cause fewer side effects.

Examples of SSRIs

Serotonin-norepinephrine reuptake inhibitors (SNRIs)

SNRIs are similar to SSRIs. They were designed to be a more effective antidepressant than SSRIs but it seems that some people respond better to SSRIs, while others respond better to SNRIs.

Examples of SNRIs

Atypical antidepressants

Atypical antidepressants don’t fit into other classes of antidepressants, but target different neurotransmitters to change the brain chemistry and regulate mood.

Examples of Atypical antidepressants

Tricyclic antidepressants (TCAs)

TCAs are the traditional type of antidepressant. They are no longer usually recommended as the first treatment for depression because they can be more dangerous if an overdose is taken. They also cause more unpleasant side effects than SSRIs and SNRIs.

TCAs respond better to severe depression and can be used for other mental health conditions, such as OCD and bipolar disorder. Amitriptyline can also be used to treat chronic pain.

Examples of TCAs

Monoamine oxidase inhibitors (MAOIs)

MAOIs are an older type of antidepressant that is rarely used nowadays. They can cause potentially serious side effects so should be prescribed with caution.

Examples of MAOIs

What are the possible side effects of antidepressants?

Antidepressant drugs can have a range of different side effects.

  • Dry mouth
  • Weight gain
  • Sexual dysfunction
  • Sexual problems
  • Constipation
  • Drowsiness
  • Sedation
  • Changes in blood pressure
  • Suicidal thoughts

The most common side effects of antidepressants are usually mild. Side effects should improve within a few days or weeks of treatment, as the body gets used to the medicine.

Talk to your doctor before you stop taking antidepressants. It’s important that you do not stop taking antidepressants suddenly. This is to help prevent any withdrawal symptoms you might get as a reaction to coming off the medicine.

Getting help

Antidepressants are a useful option for depression but there are other ways to help you cope with your symptoms of depression. Your healthcare provider can discuss other means of help. There is a nationwide network of addiction treatment centers that use behavioral health and have medical care professionals to help treat substance use disorders and underlying mental health conditions.  If you’re concerned about yourself or a loved one’s alcohol use, joining a support group or a program such as Alcoholics Anonymous may help. The National Alliance on Mental Illness is also a useful resource that provides support and information to individuals with mental illness.

What are anticoagulants?

Anticoagulants, also described as blood thinners, are a group of drugs that reduce the ability of blood to clot. Anticoagulants are used if you are at increased risk of blood clots that could potentially block a blood vessel and disrupt the flow of blood around your body. This can lead to:

  • Stroke resulting from a blood clot that restricts the flow of blood to your brain
  • Ischemic attacks have similar symptoms to a stroke, but the effects usually last less than 24 hours
  • A heart attack resulting from a blood clot that blocks a blood vessel supplying your heart
  • Deep vein thrombosis (DVT), where a blood clot forms in one of the deep veins in your body, usually your legs
  • Pulmonary embolism, where a blood clot blocks one of the blood vessels around your lungs

What do anticoagulants treat?

You may be prescribed anticoagulants in some of the following situations:

  • Recent hip replacement or knee replacement surgery – as movement is limited and blood clots may form
  • Aortic valve replacement – as blood clots can form on the surface of the new heart valve
  • Atrial fibrillation – a type of irregular heartbeat (arrhythmia) that can cause blood clots to form in the heart
  • Antiphospholipid syndrome – where the immune system attacks fats and proteins in the blood vessels, causing the blood to clot
  • To treat blood clots, such as deep vein thrombosis  DVT or a pulmonary embolism or prevent recurrent venous thromboembolism

How do anticoagulants work?

When you get hurt, blood cells called platelets gather at the injury site and form a blood clot. These cells are sticky, and they form clumps creating a plug. Clotting factors are also released from platelets that help form a mesh to form the plug to close the wound.

The clotting process is essential when you’re injured. Sometimes, however, a blood clot can appear in an artery that supplies your heart or brain with oxygen-rich blood. When a clot blocks blood flow to your heart, it can cause a heart attack. If it blocks the blood flow to your brain, it can cause a stroke. The use of blood thinners in this group of patients is common. Warfarin (Coumadin) is the most widely used anticoagulation therapy.

What are the different types of anticoagulants?

Anticoagulants are closely related to antiplatelet drugs and thrombolytic drugs by manipulating the various pathways of blood coagulation. There are three main types of anticoagulant medications:

  • Vitamin K antagonists

Vitamin K helps your blood clot. You get it naturally from green leafy vegetables like broccoli and spinach. Vitamin K antagonists such as warfarin (Coumadin, Jantoven) block the amount of vitamin K available for the blood coagulation pathway to produce clotting factors II, VII, IX, and X. This reduces the blood’s ability to clot.

It is important to keep the amount of vitamin K in your diet low so that your doctor can calculate the right dose of daily warfarin for you. You’ll get blood tests so your doctor can track the effects of your dose and your diet. Your doctor will likely use the international normalized ratio test, or INR, to check on how well your blood can clot.

  • Direct Oral Anticoagulants (DOACs)

DOACs are faster acting than vitamin K antagonists, and can also be more predictable, meaning you may not need to have blood tests. On the other hand, these drugs tend to work for shorter periods, so you may need to take them twice a day, compared to once daily for other anticoagulants.

DOACs include:

Direct thrombin inhibitors: These drugs interfere with your body’s use of thrombin, a key enzyme that helps clot your blood. Though usually injected under the skin, you can take it in pill form as dabigatran (Pradaxa).

Direct factor Xa inhibitors: Factor Xa’s job is to activate prothrombin to thrombin. This type of anticoagulant stops the Xa factor in the clotting process from carrying out its job. These medications include apixaban (Eliquis), betrixaban (Bevyxxa), edoxaban (Lixiana, Savaysa), and rivaroxaban (Xarelto).

  • Low molecular weight heparins (LMWH)

Low molecular weight heparins are more predictable and last longer, which means your doctor doesn’t need to track its effects as closely as with other anticoagulants like warfarin. Low molecular weight heparin drugs include dalteparin (Fragmin) or enoxaparin (Lovenox). Doctors prescribe a fixed-dose based on your body weight. You inject this medication under your skin.

What are the potential side effects of anticoagulants?

Anticoagulant medications increase your risk of bleeding causing adverse effects such as:

  • Passing blood in your urine
  • Severe bruising
  • Long-lasting nosebleeds
  • Sudden severe back pain
  • Difficulty breathing or chest pain
  • In women, heavy or increased bleeding during your periods, or other bleeding from your vagina

Talk with your health care provider about any side effects you may experience. The American Heart Association is also a good resource to read more about anticoagulants.

Vyvanse weight loss and binge eating disorders

Vyvanse (lisdexamfetamine dimesylate), is a stimulant medication known mainly for treating attention deficit hyperactivity disorder (ADHD) but it also has the U.S. Food and Drug Administration (FDA) approval for the treatment of Binge Eating Disorder in adults. ADHD treatments are prescribed to control symptoms such as impulsive behavior and it is this effect that is thought to work well in binge eating disorders. The FDA and Shire Pharmaceuticals the manufacturers of the drug state firmly that Vyvanse is not a weight-loss drug. Let’s take a look at how Vyvanse works in more detail and how is it used in treating binge eating disorders.

What is Vyvanse?

Vyvanse is the brand name of lisdexamfetamine, an amphetamine, and also belongs to a class of drugs known as Central Nervous System (CNS) stimulants. This means it acts on your brain to increase activity and speed up mental and physical processes.

It is used to treat symptoms of

  • Adult ADHD (Attention Deficit Hyperactivity Disorder) and ADHD in children, 6 years of age and older
  • Moderate to severe binge eating disorder (BED) in adults

As a prescription stimulant medication, Vyvanse also falls into the category of a Schedule II controlled substance. This means there is a high potential of abuse with this drug leading to severe psychological and physical dependence. The FDA highlights this risk alongside possible heart problems and psychosis, which are more likely to occur when these stimulant medications are taken.

How does Vyvanse work?

When you swallow Vyvanse, your body converts the active ingredient lisdexamfetamine into a substance called dextroamphetamine. The dextroamphetamine is transported to your brain in your blood. It passes into your brain where it causes molecules called neurotransmitters to be released.

Neurotransmitters are produced naturally in your brain and body. They are signal molecules that allow messages to travel from nerve to nerve, regulating brain activity and playing a role in thinking and behavior.

Vyvanse causes your brain to release more neurotransmitters, like dopamine, norepinephrine, and serotonin, and slows down the speed at which they’re recycled. This causes levels of neurotransmitters to build up in your brain.

What are the key uses for Vyvanse?

Vyvanse for binge eating

Binge Eating Disorder (BED) is an eating disorder where you compulsively eat large amounts of food (binge eating). You may feel out of control when you do this, and you can not stop yourself. BED receives less media attention than other eating disorders, but it may be the most common eating disorder.

Unlike the similar eating disorder bulimia, people with BED don’t purge the food afterward (such as by vomiting). Because of this, it can result in weight gain and obesity. This can lead to health problems, but also mental health issues like feelings of guilt, low self-esteem, depression, and social isolation.

It’s thought that the increase in attention and control, and the decrease in impulsivity that Vyvanse can cause also help people reduce their binge eating.

Vyvanse for weight loss

While Vyvanse can cause weight loss as a side effect, it is not approved for weight loss by the FDA. Vyvanse should only be used to treat ADHD and BED.

While one side effect of Vyvanse suppresses the desire to eat, other effects such as increased heart rate and blood pressure and raised body temperature can also cause weight loss. These physical effects of the medication on the body can increase your metabolism and some people who still eat regularly while taking Vyvanse may experience weight loss without changes to their diet.

Vyvanse for ADHD

Attention deficit hyperactivity disorder (ADHD) affects the development of your brain. It’s usually diagnosed in childhood, often between the ages of six and 12.

ADHD symptoms include problems with paying attention, impulsive behavior, regulating emotions, mood swings, and can cause restlessness and excessive activity. It can make it difficult to focus, multitask, organize yourself, and manage your time. Because of this, ADHD can disrupt your school or professional life, and the lives of people around you.

Research has shown that Vyvanse can ease the symptoms of ADHD and improve the quality of your life. It’s thought that the increase in neurotransmitters it causes, improves your focus, attention, and reduces hyperactivity and impulsivity.

How long does Vyvanse last?

Vyvanse is slower acting and has a longer duration of effect than some other central nervous system stimulants. This is because your body must convert the active ingredient lisdexamfetamine into dextroamphetamine before Vyvanse has any impact. Vyvanse also contains an ingredient called lysine (an amino acid) that slows down how quickly lisdexamfetamine can be converted into dextroamphetamine. Vyvanse usually takes around two to 12 hours to affect you. Its effects can then last up to 14 hours.

How to make Vyvanse last longer?

Some people may find that Vyvanse doesn’t last for quite as long as they’d like it to. A quick search online reveals pages and pages of advice on what you can do to prolong the effects of Vyvanse, from eating large meals when you take it, to using magnesium supplements.

There’s no scientific research behind any of this advice, so it’s best if you ignore it. If you feel your Vyvanse dose isn’t right, you should talk to your doctor about changing it (never change your dose yourself). Learn more about how to make Vyvanse last longer.

What are the side effects of Vyvanse?

If you take Vyvanse you may experience side effects.

The most common side effects caused by Vyvanse in adults taking it for BED include:

The more serious side effects that Vyvanse can cause include:

  • Serious allergic reactions
  • Serious cardiovascular reactions (heart attacks, strokes, and even death)
  • Increases in heart rate and blood pressure
  • Any new or worsening mental health problems

Vyvanse sexual side effects

Vyvanse can cause some sexual side effects. These include erectile dysfunction and prolonged erections for men. Both men and women can experience changes in their desire for sex (libido) too, both decrease and increase.

These sexual side effects don’t occur for most people who take Vyvanse. You may experience them, you may not, you won’t know until you try Vyvanse. Talk to your physician if you’re worried about sexual side effects and if you experience them while taking Vyvanse.

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What precautions should you take with Vyvanse?

Vyvanse isn’t suitable for everyone. You should speak to a healthcare professional for medical advice. You shouldn’t take Vyvanse if you:

  • Are allergic to any of the ingredients found in Vyvanse including the active ingredient lisdexamfetamine
  • Are allergic to other amphetamine products
  • Are taking monoamine oxidase inhibitors (MAOIs) like linezolid, or have taken MAOIs in the last 14 days
  • Have serious heart problems, like structural cardiac abnormalities, cardiomyopathy, serious heart arrhythmia, or coronary artery disease
  • Are under six years of age for children with ADHD
  • Are under 18 years of age for adults with BED

It is important to talk to your physician before taking Vyvanse if you:

  • Have a severe kidney condition
  • Have a pre-existing psychotic disorder, or a history of depression, bipolar disorder, or manic episodes
  • Have an addiction to alcohol or any drugs
  • Are pregnant or breastfeeding
  • Are over 65 years of age

Vyvanse FAQs

Is Vyvanse addictive?

Lisdexamfetamine, the active ingredient in Vyvanse, is a controlled substance that can be abused and become habit-forming. Vyvanse has the potential to be addictive. However, when used as prescribed to treat a medical condition, Vyvanse shouldn’t become habit-forming.

Lisdexamfetamine is converted in your body into dextroamphetamine, which is an amphetamine. Amphetamines can be used as a recreational drug. This is where they aren’t used as prescribed or to treat an indicated medical condition.

Recreational use, particularly heavy use of amphetamines, can lead to physical dependence (addiction). It can alter the way your body works. You can also become more tolerant of them, requiring higher doses to get the desired effect.

Vyvanse has less potential to be used recreationally than other amphetamines, as it’s slower acting, and won’t be absorbed quicker if it’s crushed or ground up. If used as directed by a doctor to treat ADHD or BED, it shouldn’t become addictive. Research has also shown that long-term use of stimulants from childhood to treat conditions like ADHD reduces the chances of addiction. Your healthcare provider should assess your risk of Vyvanse addiction before prescribing and should monitor you while you take it.

What are Vyvanse’s drug interactions?

Vyvanse can interact with other medications, including prescription drugs. In some instances, this can change how it and other medications work. It can even increase the likelihood and severity of some side effects. Medications that are known or thought to interact with Vyvanse include:

What is the difference between Adderall and Vyvanse?

Adderall is a similar medication to Vyvanse. Both are central nervous system stimulants derived from amphetamines, and both are used to treat ADHD. Vyvanse is also used to treat BED, but Adderall isn’t.

Although the two medications are similar and work in a similar way, they contain different active ingredients. Adderall contains four different kinds of amphetamine salts, whereas Vyvanse only contains levoamphetamine, which is converted to dextroamphetamine inside your body.

Both Vyvanse and Adderall are effective treatments for ADHD, and they cause similar side effects. Vyvanse only has an effect once it’s been converted in your body, it’s thought to have a lower risk of abuse than Adderall.

How does Vyvanse make you feel?

People react to medications differently. Vyvanse can improve your focus, make you feel more alert, and help reduce impulsivity. It can have side effects though. Some people report that Vyvanse makes them feel tired, irritable, and nauseated. These side effects are felt less often than the benefits of Vyvanse.

How long does it take for Vyvanse to work?

This varies by person. It depends on your condition, your health, and how you react to the meds. For most people, Vyvanse takes between two to twelve hours to affect you.

How long does Vyvanse stay in your system?

This depends on how your body reacts to the medication and the dose you take. On average, Vyvanse stays in your blood for up to eight hours and in your urine for around three days.

Chantix and alcohol: can they be used together?

Cigarette smoking is less common than it was a decade ago, but among those with substance use disorders, it remains highly prevalent. In fact, roughly 40% of heavy-drinking smokers admit alcohol abuse was a factor in their unsuccessful attempts to quit smoking. Naturally, this leaves you confused and puzzled over whether or not a drug like Chantix can be mixed with alcohol. Unfortunately, the risks of combining Chantix with alcohol may be dangerous to people who struggle with addiction. Nicotine increases the rewarding effects of alcohol and vice versa. Both habits are major public health concerns and put users at increased risk for diseases like coronavirus. If you are someone who is curious about taking Chantix while using alcohol, continue reading.

What is Chantix?

Chantix is manufactured by Pfizer for smoking cessation in adults. It contains the active ingredient varenicline and is approved by the U.S. Food and Drug Administration (FDA) for adults who want or need to stop smoking.

What does Chantix do to make you quit smoking?

Firstly you need to understand how nicotine from cigarettes affects you. When you smoke, nicotine is sent to your brain, where it attaches to nicotine receptors. A chemical called dopamine is released, making you feel good. Your dopamine levels then drop. This makes you want another cigarette. Dopamine is part of the reward system in the brain because when it’s released, it makes you feel calmer and happier.

So, what happens when you take Chantix? Chantix binds to nicotine receptors in the brain, taking the place of nicotine. Dopamine is still released, but in much less quantity than in response to nicotine. Over time Chantix causes this reduction in dopamine to help people reduce their cravings for cigarettes, slowly leading to finally quitting smoking.

It is important to remember not to use Chantix with a nicotine patch or any other nicotine replacement product. It may cause nausea, vomiting, headache, dizziness, and tiredness to happen more frequently than if you just used a nicotine patch alone.

What is the most important information I should know about Chantix?

Nicotine withdrawal symptoms will occur when you try to quit smoking including depressed mood, difficulty concentrating, and irritability. Some people have even experienced suicidal thoughts when trying to quit smoking without medication. Sometimes quitting smoking can lead to worsening of your pre-existing mental health problems, such as depression. Report side effects involving varenicline to the FDA MedWatch FDA Adverse Event Reporting System.

Before starting Chantix tell your healthcare provider if you have ever had depression or other mental health problems. You should also tell your healthcare provider about any symptoms you have had on other occasions you have tried to quit smoking.

Why should I avoid alcohol while taking Chantix?

  • Chantix may make you feel sleepy, dizzy, or affect your ability to concentrate, making it hard to carry out activities safely. Be cautious when driving or operating machinery until you know how Chantix affects you
  • Higher rates of comorbidities such as mental health conditions and drug abuse are seen in people with alcohol dependence
  • The Chantix website strongly recommends reducing the amount of alcohol that you drink during treatment until you know how it affects your ability to tolerate alcohol. Some people have experienced aggressive behavior and other neuropsychiatric side effects on mood or thinking when drinking alcohol during treatment with Chantix

How effective is Chantix?

In a study published by The American Journal of Psychiatry, two prescription drugs, Chantix and naltrexone were given to 165 people for alcohol dependence. Participants taking both drugs together managed to cut their alcohol consumption from an average of seven beverages per day down to three. However, people taking just Chantix or a placebo reduced their alcohol use from seven drinks to four. Using Chantix alone produced similar results to using both medications at the same time. It is also important to note 20-25% of the patients in the study were also heavy drinkers.

JAMA Psychiatry published a trial finding that varenicline vs placebo resulted in a larger decrease in the percentage of heavy drinking days in men and a smaller decrease in women. No heavy drinking days were reported by 29% of men taking varenicline vs 6% taking placebo.

Six large clinical trials by Pfizer involving 3659 heavy smokers looked at the effectiveness of smoking cessation medications. The clinical trials found that Chantix helped more people quit smoking compared with the nicotine patch and sustained-release bupropion (Zyban). This study included people both with and without a history of mental health conditions.

Where to get help?

If you or your loved one is struggling with substance abuse or alcohol use disorder talk to your healthcare provider to discuss treatment options. Healthcare professionals can provide you with the most up-to-date and accurate information.

The National Institute on Drug Abuse is an online resource available for you or someone you are concerned about.

Vraylar and alcohol: can they be used together?

Alcohol use can make it extremely challenging to control the symptoms of schizophrenia and bipolar disorder. Studies have shown that people with these medical conditions struggle significantly more with substance abuse. Vraylar can help with schizophrenia and bipolar disorder but when taken with alcohol the side effects are amplified leading to possible life-threatening situations. Medical professionals advise against mixing these two substances. Read on to gain a better understanding of why it’s not a good idea to mix the two.

What is Vraylar?

Vraylar is the brand name of a prescription drug called cariprazine. Cariprazine rebalances dopamine and serotonin to improve thinking, mood, and behavior. It belongs to a class of drugs called atypical antipsychotics and is indicated for the treatment of bipolar disorder. Atypical antipsychotics are used in adults, on their own, or in combination with mood stabilizer drugs such as lithium. Other antipsychotic drugs in this drug class include quetiapine (Seroquel), aripiprazole (Abilify) risperidone, quetiapine, and olanzapine.

Vraylar is an FDA-approved atypical antipsychotic medication used to treat adult mental health conditions such as:

  • Schizophrenia
  • Short-term episodes of bipolar mania in people with bipolar disorder
  • Bipolar depressive episodes in people with bipolar disorder

Vraylar is not approved for use in older adults with dementia-related psychosis due to an increased risk of death. Missing doses of cariprazine may also cause a deterioration in symptoms. Using an app as a reminder may be a good way to prevent this from happening.

What are the side effects of Vraylar?

The most serious side effects of Vraylar include:

  • Tardive dyskinesia (uncontrollable slow or jerky movements)
  • Low white blood cell count
  • Increased prolactin levels causing missed periods in females
  • Neuroleptic malignant syndrome
  • Changes in your metabolism can lead to high blood sugar levels, high levels of cholesterol or triglycerides, and weight gain

More common side effects of Vraylar include:

  • Muscle stiffness
  • Drowsiness

Drug interactions and supplements

Vraylar can interact with different types of drugs. Some drugs include:

  • CYP3A4 inducers and inhibitors
  • Heart medications such as diltiazem (Cardizem) and verapamil (Isoptin) for the treatment of high blood pressure
  • Mood stabilizers like carbamazepine (Tegretol) and lithium
  • Opioid medication

This is not a complete list of drug interactions for Vraylar. Consult your healthcare provider for medical advice and tell them about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Is Vraylar safe in pregnancy and breastfeeding?

It is not known if Vraylar passes into breast milk. If you are breastfeeding or planning to breastfeed, or are pregnant or planning to become pregnant speak with your doctor about the risks and benefits of using Vraylar.

What can happen if I drink alcohol with Vraylar?

Increase in side effects and symptoms

Alcohol and Vraylar have many common side effects because they are both central nervous system depressants. Alcohol can cause a worsening of symptoms and side effects of bipolar disorder or schizophrenia. You are at an increased risk of some of the following side effects when you combine the two:

  • Low blood pressure
  • Reduced heart rate
  • Reduced rate of breathing
  • Sedation
  • Lightheadedness
  • More likely to fall
  • Seizures

You should avoid drinking alcohol as it may worsen the side effects of Vraylar. If you take atypical antipsychotics, talk with your healthcare provider before drinking any alcohol.

Increased risk of substance abuse

When you have depression, you have an increased risk of developing a substance use disorder. Therefore mixing antidepressants with alcohol can lead to alcohol abuse, increasing your potential to become alcohol dependent. If you drink and develop an addiction to alcohol, it will become more difficult for you to control your symptoms of depression and get your alcohol consumption under control. You may need more frequent and long-term treatment if you have both an alcohol use disorder and depression. Vraylar’s prescribing information doesn’t list alcohol as a contraindication or warning but is it strongly discouraged by healthcare professionals.

The combination of alcohol and antidepressants can be very challenging if someone is drinking, binge drinking, heavy drinking, or has an alcohol use disorder prior to taking the antidepressants. Furthermore, if someone decides to stop taking drugs for depression and starts drinking alcohol for symptom management instead, they can worsen their symptoms of depression, in some cases leading to suicidal thoughts.

Get help

The cocktail of symptoms of schizophrenia/bipolar disorder and alcohol withdrawal symptoms can be difficult to cope with, without medical advice and guidance. If you are worried about yourself or a loved one some of the following resources may be of help to you – SAMHSA – Substance Abuse and Mental Health Service or The National Institute of Mental Health. Your doctor or healthcare provider can also help you make decisions about your meds, provide drug information and discuss the adverse effects of combining Vraylar with alcohol.

Xifaxan and alcohol: can they be used together?

Drinking alcohol with Xifaxan should be considered carefully. If you are taking Xifaxan it means you have an infection that needs treating because your immune system is weak. Since drinking alcohol can lower your body’s immune system you risk prolonging the time it takes for your body to repair. Read on to find out how Xifaxan works and why it may be beneficial to not drink while taking the drug.

What is Xifaxan?

Xifaxan belongs to a class of drugs called antibiotics that targets bacterial infection in the intestines by disrupting its growth. It is manufactured by Salix Pharmaceuticals and contains the active ingredient rifaximin (derived from rifamycin). Xifaxan is a prescription medicine that is approved by the US Food and Drug Administration (FDA) to treat the symptoms of traveler’s diarrhea, hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D).

What is the dosage for Xifaxan?

  • Rifaximin 200 mg tablets, one three times a day for three days for adults to treat traveler’s diarrhea caused by Escherichia coli bacteria. In children use and dose must be determined by your doctor
  • Rifaximin 550 mg tablets, one twice daily are used to prevent episodes of hepatic encephalopathy (when the liver stops working and cannot remove toxic substances from the body) in adults who have liver disease or liver failure
  • Rifaximin 550 mg tablets, one three times a day for 14 days to treat irritable bowel syndrome with diarrhea. In children, the dose must be determined by your doctor

Do not take a double dose to make up for a missed dose. Take your next dose as usual. If you are not sure what to do after missing a dose, contact your healthcare provider.

The most common side effects of rifaximin include:

  • Nausea
  • Headache
  • Dizziness
  • Tiredness

Always consult a healthcare professional for medical advice if more serious side effects occur such as severe stomach pain along with watery or bloody diarrhea, or an allergic reaction to the drug causing hives on the skin.

What should I tell my doctor about before starting Xifaxan?

  • To minimize drug interactions inform your doctor about other prescribed medications and over-the-counter medications you may be taking to treat other medical conditions.   Cyclosporine is an important drug to mention. Any nutritional supplements and herbal products should be mentioned too
  • Inform your doctor if you have or have ever had liver disease
  • If you are pregnant, planning a pregnancy, or are breastfeeding

Get your Xifaxan medication for only $49 per month

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Is Xifaxan safe with alcohol?

Yes but pharmacists and healthcare professionals advise against it. A retrospective study by The American College of Gastroenterology showed an association between moderate alcohol consumption and small intestinal bacterial overgrowth. Just one drink per day for women and two for men is linked to small intestinal bacterial overgrowth leading to gastrointestinal symptoms like bloating, gas, abdominal pain, constipation, and diarrhea. This highlights that consuming even the slightest amount of alcohol could have an impact on your gut health.

Therefore drinking alcohol will impact negativity on the conditions Xifaxan is used to treat, particularly IBS-D and traveler’s diarrhea. Patients with cirrhosis i.e. liver disease are predisposed to intestinal bacterial overgrowth meaning patients with hepatic encephalopathy need to think carefully before drinking alcohol.

Is NiceRx Legit?

Many people are not aware that prescription assistance programs exist and NiceRx can help eligible individuals access these programs. U.S. pharmaceutical companies offer patient assistance programs but they are not actively marketed by them. It’s no surprise if this is the first time you have heard of them or have had challenges identifying the right programs and applying for assistance.

NiceRx is a legitimate company that provides courteous and professional assistance (Monday-Friday 8am-5pm EST) to people who cannot afford their medications, who may be insured, ineligible for Medicare, underinsured or uninsured. It’s a fact that Americans spend more on prescription drugs than any other country in the world, and we are here to help. Read on to find out how NiceRx can help you and assure you that it’s no scam!

What is NiceRx?

NiceRx is a service that works with your doctor’s office and the U.S. pharmaceutical companies that supply the medications. We are responsible for pre-qualifying you, completing the required paperwork, working with your doctor’s office, ordering, managing, tracking, on-time refilling of your medications, and renewal of your enrollment. Our advocates will identify all available sources of assistance for you. NiceRx makes the process of accessing FDA-approved prescription medications through pharmaceutical companies easier.

NiceRx is not an insurance plan or discount card. You can learn more about us.

What is a prescription assistance program?

Pharmaceutical companies in the U.S. offer patient assistance programs. These programs are available for eligible individuals who meet the income and insurance guidelines set by the pharmaceutical companies to receive their medications at a low cost, or for free.

NiceRx handles the entire process for you including the pre-qualification, ongoing application process, requesting refills on your behalf, and renewal of your enrollment in the program.

How does NiceRx work?

NiceRx is a full-service medication access company for individuals who are struggling to afford their prescription medication due to the high cost of the medication or copays.

You will complete your online enrollment securely on our website and will be notified in real-time if any of your medications are qualified for assistance. Once you become a NiceRx customer, we will start working with your doctor and the U.S. pharmaceutical companies to enroll you in the assistance program, handle your ongoing refills for your prescription drugs, and maintain enrollment with the assistance program.

You can learn more about how it worksGet Started with your online enrollment and find out if you are qualified for assistance.

How much does NiceRx cost?

NiceRx charges a service fee of $49 per month for each eligible medication we are able to assist with. There are no additional fees or costs for our service and the medications are supplied for free. There is no limit on the number of medications you can apply for. NiceRx provides access to over 1,500 FDA-approved medications, which you can apply for. The service fee applies to each eligible medication, so please remember if you were to enroll and be approved for e.g. two medications, then the cost will be $98 per month. You will not be charged for any medications we are unable to help with.

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What are the benefits of NiceRx?

NiceRx helps eligible individuals access over 1,500 FDA-approved brand-name medications at an affordable price. We work with your healthcare provider to save you time, money, and worry. We will request your ongoing refills and renew your enrollment when it’s due. We are here every step of the way for you.

What do we ask from you?

As a NiceRx customer, you can expect the following:

  • You will be required to provide all required documents for enrollment including income verification (eg. pay stubs, tax return, etc.) which can be uploaded securely online.
  • Once a year, you must provide us with the requested information about your medications and income to continue to qualify for the program.
  • You will pay a monthly service fee of $49 for each medication you’re approved for. There are no hidden or additional fees.

FAQ’s

What information do you need from me?

In order to complete the online enrollment form, you will need the following information on hand which will be required by the pharmaceutical companies:

  • Your name, address, date of birth, SSN
  • Insurance details
  • Income details
  • Physician details
  • Medication details
  • Payment details

How do you use and disclose protected health information about me?

NiceRx is committed to maintaining your privacy and we take our responsibility for safeguarding this information very seriously.

Protected Health Information (PHI) is the information we obtain to provide services to you that can identify you. PHI includes your name, medical conditions, health information, and other information we use to provide your prescriptions. We are required to adhere to the terms outlined in this Notice.

The following categories describe the ways that we use and disclose health information. Not every use or disclosure in a category will be listed. However, all of the ways we are permitted to use and disclose information will fall into one of the categories.

For Treatment. PHI obtained by NiceRx will be used so that appropriate persons and entities can dispense your prescription medications. We may disclose health information about you to patient assistance programs (“PAPs”), and to doctors, nurses, other health care providers who are involved in taking care of you.

For Payment. We may use or disclose your PHI to your insurer, payor, or other agents in order to bill and collect payment for items or services we provided to you. For example, we may contact your insurance company, health plan, or another third party to obtain payment for services we provided to you. We may also contact you about a payment or balance due.

For Health Care Operations. We may use and disclose health information about you for our day-to-day health care operations. For example, we may use your PHI to monitor the performance of the staff providing services to you. We may use your PHI to continually improve the quality and the effectiveness of the health care products and services that we provide to you. We may search various data providers and other healthcare providers in order to ensure we have accurate medical records as a means to ensure the highest quality of care.

You can learn more in our Notice of Privacy Practices and Privacy Policy.

Why do you need my doctor’s details?

We require your doctor’s details because your doctor will need to be involved in the application process. We will send your doctor a request for a prescription. Once we receive the signed prescription from your doctor, we can proceed to finalize the application with the pharmaceutical manufacturer. In some instances, we may require your assistance in expediting the request for the prescription from your doctor. In these instances, we will notify you if we are still waiting for your prescription and require your assistance.

Why do I need to chase my doctor for a prescription?

Once you complete your enrollment and send us the outstanding documentation, we proceed to request a prescription from your doctor. Generally, doctors’ offices do respond positively to requests for a prescription. We require a prescription from your doctor to progress your application. At times when we cannot get a positive response from your doctor, we may request your assistance. Ultimately, the faster we get the prescription from your doctor, the quicker you may receive your medication.

Why do you need my total household income when it’s just myself enrolling?

Each pharmaceutical company has its own eligibility criteria. Some require the total household income to determine if an individual is eligible to receive medication from them.

I don’t have a job and I have no income. Can I still apply?

Each pharmaceutical company has its own eligibility criteria. You may still apply if you don’t have a job, although you may be required to provide evidence of this (e.g., employment termination letter).

How will I know if my enrollment has been successful?

Once you complete and submit the online enrollment form, you will receive an email informing you of the outcome. If you are successfully qualified, you will be requested to sign and send back a Consent Form; this allows us to act on your behalf and progress with your application. In addition, you will receive a link to your ‘My Account’ page, where you will be required to upload requested documents (e.g., insurance card, IRS-1040, W2, IRS-1099, etc.).

What happens if my enrollment is unsuccessful? Can I reapply?

Yes. Pharmaceutical manufacturer programs change from time to time. Therefore, if you have been unsuccessful in the past, it does not mean you will be unsuccessful in the future. In addition, if your circumstances change, this could potentially change your eligibility for assistance. We recommend that you regularly check even if you are not qualified. There is no cost or charge for checking.

Why do I need to upload documents?

Documents requested are specific to the medication you are requesting assistance with and relate to the requirements set by the manufacturer. Without these documents, the application will be delayed so we strongly suggest uploading the required documents as soon as possible.

How do I upload my documents?

All applicants will have access to a ‘My Account’ page where you can review the application and upload any documents required. You can access your online account via a link in the email that we send you after you complete your online enrollment; otherwise, you can access it via the website account login.

Can I complete the enrollment and send my documents later?

Yes, however, we do not recommend this because it may lead to a delay in you receiving your medication.

If I have successfully enrolled and provided all information requested, can I still be rejected?

In a very small number of cases, this may actually happen. However, in our experience, this is very rare. Ultimately, the manufacturer has the final say in approving supply. We will always keep you updated and if there is a rejection, you will be fully refunded.

The Solo Living Index

Which are the best US states to live independently?

For many people living alone is a liberating experience, leaving them free to live life on their own terms and foster greater independence from others. It can also be an unfortunate necessity as we grow older. However, The rising cost of living can also make it difficult for some living on a single income to afford essentials like prescription medications, rent, food, and utility bills.

But which is the best US state to be a young single person, and which state is best for elderly singles? NiceRx has delved into the data, looking at cost of living and healthcare factors to reveal the best locations for the single life, both young and old.

Best-states-for-solo-living

⦁ Idaho
Solo living Score: 6.5/10

Taking the top spot on our list with a score of 6.5 is Idaho. Nicknamed the gem state because of its breathtaking landscapes, Idaho is perfect for solitary nature lovers. With wide-open spaces and friendly neighbors, it scored as one of the safest places in our index. The state also has a high number of group activities per 100,000 people.

⦁ Nebraska
Solo living Score: 6.4/10

One of the most affordable states for rent in our index, making it perfect to live comfortably on a single income, Nebraska ranks second with an overall score of 6.4. The state also ranks highly for the number of hospitals per 100,000 and is among the safest locations in our index too. Most of Nebraska’s population live rurally, so it’s an ideal state for those who wish to move to a place with a slower and more peaceful lifestyle.

⦁ Louisiana
Solo living Score: 6.3/10

Taking third place in our index is Louisiana with a score of 6.3. The state benefits from a relatively low cost of living and ranks in the top 10 lowest rent prices. As well as having a relatively high number of single-person households, Louisiana has one of the highest numbers of group activities per 100,00 people, solidifying its reputation as the festival capital of America and as an ideal place for those living on their own to meet new people.

Best-state-for

 

Lowest rent – Kentucky ($763 average monthly rent)

Affordability of housing is a chief concern, with rent prices differing drastically across states. The cheapest US state in terms of rent is Kentucky, with a median rent price of $763 per month for a 1 bedroom apartment in the bluegrass state.

Lowest Cost of living – New Mexico (63.9 cost of living index score)

One of the most important things to consider when moving to a new state is determining the amount of money you need to spend on food energy bills and taxes. In our index, New Mexico had the lowest cost of living index, with its residents giving it a cumulative score of 63.9 out of 100. This could be due to the fact it has some of the lowest state and local taxes in the country.

Safest state for solo living – Utah (67.2/100 safety score)

The crime rate is another important factor when thinking about moving to a new area, especially if you’re living alone. When looking into the safety of each state, Utah ranks as the most secure with an index score of 67.2 out of 100, according to submissions from its residents.

Most singletons – New Mexico (31.3% single-person households)

One key aspect of deciding which state to relocate to is finding like-minded people. In this case, people who also live independently. We found that New Mexico has the highest percentage of single-person households, with 31.3% living alone.

Number of group activities per 100,000 – Colorado (5.80)

Moving to a new state on your own can be a lonely experience for some and many people choose to join in with group activities, such as community volunteering projects and exercise classes, in order to make friends. With this in mind, we found Colorado has the highest number of group activities per 100,000 at 5.80.

Number of hospitals per 100,000 – Alaska (16.7)

Access to healthcare is vital to consider when thinking about moving to a new state. Alaska had the highest, with 16.7 per 100,000 people, perhaps due to its low population.

Number of health centers per million – Florida (6.47)

As well as hospitals, health centers play a key role in deciding where to relocate, in order to keep you healthy and happy in your new home state. Florida has the most health centers with 6.47 per million people.

Average annual health insurance cost – New Mexico ($6,088)

The cost of health insurance is essential to consider when thinking about which state to relocate to, as it’s important to give yourself financial protection in case of an accident or a serious illness. New Mexico has the cheapest average health insurance with a cost of $6,088 per year.

Best-for-elderly-solo-living

⦁ Utah
Solo living Score: 7.5/10

Coming first in our rankings is Utah with a score of 7.5. The state has a very low cost of assisted living coupled with a high number of assisted living facilities as well as scoring highly for healthcare quality. Utah’s thriving economy and ample opportunities for retirees to keep active make it an attractive location for older generations.

⦁ Idaho
Solo living Score: 6.6/10

With a score of 6.6, Idaho comes second in our index. Like Utah, Idaho has a high number of assisted living facilities per 100,000 people, twinned with a relatively low cost of assisted living. The state also ranks highly for healthcare quality. Known for its scenic beauty, Idaho is the perfect place for retirees who love to commune with nature.

⦁ Wisconsin
Solo living Score: 6.4/10

This state scored 6.4, taking it to third place in our index. Wisconsin scores relatively highly for both healthcare quality and accessibility. It also has a high number of assisted living facilities per 100,000 people. Famous for its cheese production and the Green Bay Packers, Wisconsin holds much more for retirees, with a strong sense of community and a passion for festivals as well as more than 500 golf courses, Wisconsin is an attractive destination for solo retirees.

Best-state-for

Assisted living facilities per 100,000 – Oklahoma (35 per 100,000 population)

An important factor to consider when choosing a state to move to as a single elderly person is perhaps choosing an assisted living facility, as they provide numerous benefits such as safety and the ability to socialize. With this in mind, Oklahoma takes the top spot for assisted living facilities, with 10 more per 100,000 than its closest competitor at 35 per 100,000.

Lowest cost for solo living – North Dakota ($29,149 per year)

Also, a key factor is the cost of assisted living facilities, as this can vary greatly by state as well as the fact that people are increasingly living longer. This may put a strain on many retirees’ pensions, especially if they’re only relying on a single pension. North Dakota ranks first in our index, with the lowest average cost of $29,149 per year.

Lowest pension needed to live comfortably – Mississippi ($44,758 per year)

Managing your finances can be difficult when you’re on a single fixed income, making it important to think about how far your pension will go in terms of the cost of living. Mississippi has the lowest average annual pension required to live comfortably at just $44,758 leaving many free to enjoy their retirement without money worries.

The best state for healthcare access – Hawaii

Access to healthcare can become a top priority for many elderly people wishing to relocate on their own. With this considered, the best state for healthcare access is Hawaii, coming top of our list.

The best state for healthcare quality – Hawaii

As well as having plenty of access to healthcare, it’s important that elderly people get the highest quality healthcare too. As with healthcare access, Hawaii also comes first in healthcare quality.

The best state for public health – California

Keeping healthy is vital in old age, with public health programs helping to prevent the biggest threats to the health and wellbeing of the population. California tops the ranking for public health, making it one of the most health-conscious states.

Assistance with prescription drug prices

NiceRx helps individuals access over 1,500 FDA-approved brand name medications including Ozempic, Linzess, Xarelto, Brilinta, Janumet XR and Januvia.

Methodology

We looked at each US state, ranking each on the following factors, giving them a normalized score out of 10 for each factor before taking a final average score across all ten. Note that some states had to be omitted due to a lack of data.

Median monthly rent for 1 bedroom
The average cost of a 1 bedroom apartment in each state in 2022 according to world population review.

Percentage of single-person households
The percentage of single-person households in each state as of 2019, taken from Statista.

Safety score
The average safety index scores of cities – grouped by state – according to Numbeo.

Cost of living
The average cost of living index scores of cities – grouped by state – according to Numbeo.

Activity groups
The number of events listed on eventbrite in each state for the month of March, per 100,000 people.

Hospitals
The number of hospitals in each state according to the Health Resources and Services Administration, per 100,000 people.

Number of health centers
The number of health centers in each state according to the Health Resources and Services Administration, per million people.

Average health insurance cost $
The average of per enrollee private health insurance spending on personal health care, per enrollee Medicaid spending on personal healthcare, and per-enrollee medicare spending on personal healthcare from 2019 or the latest data available from datausa.

Population Figures
The population totals by state according to world population review.

Number of assisted living facilities
The total number of assisted living facilities in each state in 2021 according to Consumer Affairs, per 100,000 of the state population.

The average yearly cost of assisted living
The average cost of an assisted living facility per year in each state, according to Consumer Affairs.

Average annual pension needed to live comfortably
The average yearly expenses of retirees to afford a reasonable standard of living by state, according to world population review.

Healthcare access rank
A state’s ranking based on adult and child wellness visits is taken from USA News 2021 Healthcare rankings.

Healthcare quality rank
A state’s ranking based on healthcare setting quality taken from USA News 2021 Healthcare rankings.

Public health rank
A state’s ranking based on health behaviors is taken from USA News 2021 Healthcare rankings.

Bipolar and alcohol

Bipolar disorder and alcohol abuse unfortunately have a strong link. Studies have shown that people with bipolar disorder have a 60% chance of developing a drinking problem at some point in their lives. With this statistic in mind, how do you feel about combining the two? What if you have bipolar disorder and want to enjoy alcohol occasionally? Experts believe that anyone with a substance use disorder such as alcohol abuse, drug abuse, or addiction should be screened for bipolar disorder. Read more to learn about bipolar disorder, alcohol use disorder (AUD), and the connection between these conditions.

What is bipolar disorder?

The National Institute of Mental Health describes bipolar disorder (often called manic depression) as a mental health disorder that occurs occasionally and at irregular intervals causing unusual, often extreme, and fluctuating changes in mood, energy, activity, and concentration or focus. Your diagnosis will normally be made by a healthcare provider that specializes in psychiatry.

Bipolar I disorder

The dominant symptom of bipolar I disorder is manic episodes that last 7 days which may or may not lead to hospitalization. Also, a depressive episode lasting typically two weeks will normally occur. These manic and depressive episodes can happen separately or at the same time. Psychosis (losing touch with reality), impulsivity, racing thoughts, mood swings, extreme irritation, and sleeping very little are some of the symptoms characterized by a manic episode.

Bipolar II disorder

The main symptom is depressive episodes with hypomania, but not complete manic episodes like Bipolar I. This disorder is slightly less intense than Bipolar I. Symptoms of bipolar disorder II are dominated by feeling down, being unable to make decisions, talking slowly, having little interest in activities, trouble falling asleep, or sleeping too much.

As you can see mood disorders or psychiatric disorders can be complex and difficult to handle due to the extreme changes in symptoms. When alcohol dependence is added into this you have a dual diagnosis or a co-occurring disorder and treatment becomes even more complicated. The co-morbidity of AUD in bipolar disorder can reach 45% and the odds ratio for AUD in bipolar I disorder is higher than for bipolar II disorder.

Treatment for bipolar

Mood stabilizers and antipsychotics are the commonly used drugs used to treat bipolar disorders. Mood stabilizers such as lithium (Lithobid), valproic acid (Depakene), and divalproex sodium (Depakote) can help extreme shifts in mood or reduce their intensity when they occur. Lithium also decreases the risk for suicide. Antipsychotic medications such as olanzapine (Zyprexa), lurasidone (Latuda), brexpiprazole (Rexulti), risperidone (Risperdal), and quetiapine (Seroquel XR) are commonly prescribed. Bipolar disorder treatment plans often include medications such as antidepressants alongside mood stabilizers.

What are the effects of drinking alcohol when you have bipolar?

Increases the intensity of your symptoms

Due to the impulsive and risk-taking behaviors of a bipolar condition the likelihood of alcohol abuse is higher as mentioned earlier. Developing an alcohol abuse disorder can worsen the symptoms of bipolar conditions and its side effects like dizziness, memory impairment, confusion, poor judgment, or increased risk for falls and injury. Individuals present with more manic symptoms than individuals with bipolar who do not drink alcohol. For this reason, even drinking alcohol sensibly can be a risk.

Dangerous drug interactions

There is a high possibility you are also on other psychiatric medications to treat your bipolar conditions. You may be on a drug cocktail of medications to treat bipolar, depression, and schizophrenia. Alcohol does not mix well with many medications, particularly those to treat mood disorders. The addition of alcohol can cause troublesome or even dangerous side effects.

Alcohol masks problems in your life

You sometimes hear people saying alcohol makes me more confident, it makes me forget about my worries or it takes the edge of racing thoughts. This only lasts for a moment, a few hours, or even a day. You are then back to where you were. As long you use alcohol to self-medicate your mental illness, you won’t take the time to develop your coping strategies and it will hinder your recovery. Masking your problems will only delay getting better.

Steps to recovery

Inpatient alcohol detox and rehab is normally the first step in recovery. Symptoms of bipolar and alcohol withdrawal can be difficult to cope with without medical supervision therefore many people seek an inpatient treatment facility. Outpatient care is also an option that requires extra support from your loved ones. Many interventions and treatment options can be put in place to help improve your quality of life. Group therapy with friends, family members, or others in the same position as you and cognitive behavioral therapy are to name a few.

If you are worried about yourself or a loved one some of the following resources may be of help to you – SAMHSA – Substance Abuse and Mental Health Service or The National Institute of Mental Health

Antidepressants and alcohol: can they be used together?

Taking antidepressants and drinking alcohol together are strongly discouraged by healthcare professionals. Both work on slowing down the central nervous system causing drowsiness, sedation, and impairment. When taken together however they can create health problems for you, impact your mental health further, cause challenges in your home life with loved ones, and other serious concerns. In the US, 13.8 million people received treatment for depression in 2020. People tend to forget that antidepressants can have dangerous side effects and interactions with alcohol because of how commonly they’re used. Read on to find out how drinking can make depression symptoms more severe and harder to treat.

How do antidepressants work?

Antidepressant medications generally work by balancing neurotransmitters such as serotonin, norepinephrine, dopamine, and gamma-aminobutyric acid in the brain. By rebalancing their levels symptoms of depression can be prevented from worsening.

What are the effects of alcohol on different types of antidepressants?

There are various classes of antidepressants:

Monoamine oxidase inhibitors (MAOIs)

Certain alcoholic beverages contain a substance called tyramine that can cause serious side effects if consumed while on an MAOI. Side effects include a sudden, dangerous increase in blood pressure. Doctors will advise you against alcohol use if you are taking an MAOI. Tyramine is also found in certain foods, so your healthcare provider will give you advice on which foods to avoid. Excessive tyramine in the body can also cause dangerously high blood pressure. Marplan (isocarboxazid), Nardil (phenelzine), and Emsam (selegiline) are commonly prescribed MAOIs.

Selective Serotonin Reuptake Inhibitors (SSRIs)

The most commonly prescribed SSRIs are Paxil (paroxetine), Prozac (fluoxetine) Lexapro (escitalopram), Trintellix (vortioxetine), Viibryd (vilazodone) and Zoloft (sertraline).

SSRIs don’t usually cause problems if someone drinks while taking them, but these medications can make patients drowsy, and alcohol can intensify this effect.

Serotonin-noradrenaline reuptake inhibitors (SNRIs)

SNRIs are similar to SSRIs and are intended to be more effective anti-depressant than SSRIs.  There is evidence that some people may respond better to SSRIs, while others respond better to SNRIs. Examples of SNRIs include Cymbalta (duloxetine), Pristiq (desvenlafaxine), Effexor (venlafaxine) and Fetzima (levomilnacipran).

Tricyclic antidepressants (TCA)

TCAs show their greatest side effects during the first few weeks of treatment. At this point, it is not a good idea to consume alcohol. A few weeks after side effects have passed it’s generally considered safe to drink small amounts of alcohol. Elavil (amitriptyline), Silenor (doxepin), and Pamelor (nortriptyline) are commonly prescribed TCAs.

How is my mental health affected by drinking alcohol?

Medication can worsen the effects of alcohol, while alcohol can worsen antidepressant side effects. When you have depression, you have an increased risk of developing a substance use disorder. Therefore mixing antidepressants with alcohol can lead to alcohol abuse, causing you to have the potential to become alcohol dependent. If you drink and develop an addiction to alcohol, it will become more difficult for you to control your symptoms of depression and get your alcohol consumption under control. You may need more frequent and long-term treatment if you have both an alcohol use disorder and depression.

The combination of alcohol and antidepressants can be very challenging if someone is drinking, binge drinking, heavy drinking, or has an alcohol use disorder prior to taking the antidepressants. Furthermore, if someone decides to stop taking drugs for depression and starts drinking alcohol for symptom management instead, they can worsen their symptoms of depression, in some cases leading to suicidal thoughts.

Getting help

Antidepressants are a useful option for depression but there are other ways to help you cope with your symptoms of depression. Your healthcare provider can discuss other means of help. There is a nationwide network of addiction treatment centers that use behavioral health and have medical care professionals to help treat substance use disorders and underlying mental health conditions.  If you’re concerned about your or a loved one’s alcohol use, joining a support group or a program such as Alcoholics Anonymous may help. The National Alliance on Mental Illness is also a useful resource that provides support and information to individuals with mental illness.

Switching from Eliquis to Xarelto

It is not uncommon to want to transition from one anticoagulant drug to another. There are many different reasons. It could be the cost, your personal preference, other medical conditions you may have, a hospital stay, bleeding complications, or you’ve had a procedure. Before switching from Eliquis to Xarelto, let’s take a brief look into how these two drugs work.

What are Eliquis and Xarelto?

Eliquis and Xarelto are brand names for blood thinners used to prevent blood clots. Both are prescription drugs approved by the FDA. Eliquis is manufactured by Bristol-Myers Squibb. Xarelto is made by Janssen Pharmaceuticals. Both drugs are direct oral anticoagulants (DOAC) classed as factor Xa inhibitors. They work by directly blocking a single blood clotting factor in the body called Factor Xa. In contrast, warfarin targets various clotting factors.

These drugs were developed as an alternative to warfarin (Coumadin) to reduce the need for regular blood tests for INR (International Normalized Ratio) monitoring to ensure levels remain in a therapeutic range. INR is a laboratory measurement of how long it takes blood to clot, therefore it monitors bleeding risk.

What do Eliquis and Xarelto treat?

Eliquis and Xarelto can be used for some of the following indications:

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib, or irregular heartbeat)
  • Prevent deep vein thrombosis (DVT) in the legs and pulmonary embolism (PE) in the lungs of patients who have had hip or knee replacement surgery
  • Treatment of deep vein thrombosis (DVT)
  • Treatment of pulmonary embolism (PE)

The American College of Cardiology, the American Heart Association, and the Heart Rhythm Society guidelines recommend direct oral anticoagulants (DOACs), such as apixaban (Eliquis), rivaroxaban (Xarelto) dabigatran (Pradaxa made by Boehringer Ingelheim), and edoxaban (Savaysa) for most people with atrial fibrillation (Afib). There are some exceptions e.g. people with mechanical heart valves and moderate to severe mitral-valve narrowing should still use warfarin. Warfarin and low molecular weight heparin (LMWH) are also referred to as Vitamin K antagonists.

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How do you switch between anticoagulants?

Your doctor will carry out a renal function test called creatinine clearance values (CrCl) before switching from some drugs. CrCl 30 is a value that shows moderate renal impairment. It is particularly important to have this test if you are taking an anticoagulant dose that is renally adjusted.

There are five scenarios that occur with DOAC therapy, switching from or to another anticoagulant:

  • Vitamin K antagonists to DOAC

e.g. warfarin to rivaroxaban – stop warfarin and rivaroxaban should be started when the INR is < 3.0.

  • DOAC to Vitamin K antagonists

e.g. dabigatran to warfarin.

If the CrCl level is >50 mL/min then start warfarin and stop dabigatran 3 days later.

If the CrCl level is 31 to 50 mL/min: start warfarin and stop dabigatran 2 days later.

If the CrCl level is 15 to 30 mL/min: start warfarin and stop dabigatran 1 day later.

  • DOAC to parenteral anticoagulant
  • Parenteral anticoagulant to DOAC
  • DOAC to DOAC

e.g. apixaban (Eliquis) to rivaroxaban (Xarelto).

Stop the current apixaban regimen and begin rivaroxaban at the time the next dose of apixaban is due. Due to the fast onset and offset of DOAC’s, bridging between treatments is generally not required.

The American Heart Association can give you more detailed guidelines on how to switch between anticoagulants.

Can I switch from Eliquis to Xarelto?

Yes, but it is necessary to have a consultation with your prescribing physician before switching from Eliquis to Xarelto. The best drug for you can only be determined by your healthcare provider.

When switching from Eliquis to anticoagulants other than warfarin, you must first discontinue Eliquis, and begin taking Xarelto at the time the next dose of Eliquis was due.

Blood pressure and alcohol

Blood pressure can be described as the measure of force your heart uses to pump blood around your entire body. This measurement takes into account the systolic blood pressure (when your heart muscle contracts) and the diastolic blood pressure (when your heart muscle relaxes). Keeping these two values in the normal range is important for your heart health. High blood pressure (hypertension) is known to be one of the risk factors for cardiovascular disease. Have you recently been diagnosed with high blood pressure? Has your doctor advised you on the amount of alcohol you can drink? How does drinking alcohol affect your blood pressure? Keep reading to find out the answers to these questions and more.

How does a person know if they have high blood pressure?

Drinking excessive alcohol is considered one of the most common causes of raised blood pressure, leading to other health problems. This is the reason why doctors will question a patient’s alcohol intake when a high blood pressure reading is measured. Many people don’t realize they have hypertension until they have it measured because early high blood pressure doesn’t bring on troublesome symptoms.

High blood pressure is defined per the 2017 American College of Cardiology/American Heart Association Blood Pressure guidelines as anything greater than or equal to 130/80 mm Hg. Anything below this value is considered normal blood pressure or normotensive. You may or may not have symptoms of high blood pressure. The only real way to know for sure is to have your blood pressure measured by a healthcare professional.

How does alcohol affect blood pressure?

Alcohol affects blood pressure in several different ways:

  • It causes blood vessels to constrict making them narrower and also causing more fluid to build up in the body. This combination causes increased blood pressure. i.e. a narrower blood vessel for blood flow causes increased pressure on the walls of the blood vessels
  • It prevents the blood pressure monitoring receptors in the body from working correctly. This means blood pressure levels can not be regulated correctly
  • Alcohol can be high in calories and may contribute to weight gain, another factor that increases the prevalence of high blood pressure
  • It increases the amount of calcium in the blood which constricts blood vessels further, leading to high blood pressure
  • It increases cortisol levels in the blood which has a knock-on effect to excrete less urine. This buildup of fluid pressure in the blood vessels increases blood pressure

High blood pressure can significantly increase cardiovascular risks such as your risk of stroke, heart attack, heart disease, heart rate abnormalities, or heart failure. You are also at a higher risk of kidney disease and vascular dementia.

Will quitting alcohol lower blood pressure?

Hypertension is one of the most preventable alcohol-related health risks. Reducing your alcohol consumption reduces your blood pressure. How do you know if you are a heavy drinker or a moderate drinker? Let us take a look at how the National Institute on Alcohol Abuse and Alcoholism defines it:

Heavy drinking  4 drinks on any day or more than 14 drinks per week for males. More than 3 drinks on any day or more than 7 drinks per week for females.

Binge drinking 5 or more drinks for males, or 4 or more drinks for females), in about 2 hours.

The 2020-2025 Dietary Guidelines for Americans describes:

Moderate drinking as 2 drinks or less in a day for men and 1 drink or less in a day for women.

The Lancet looked at systematic reviews specifically on the effect of a reduction of alcohol intake on blood pressure. It was found that people who drank two or fewer drinks per day, a reduction in alcohol was not linked with a significant reduction in blood pressure. However, in people who drank more than two drinks per day, a reduction in alcohol intake was associated with increased blood pressure reduction.

There is some evidence that moderate amounts of alcohol in particular red wine might help to slightly raise levels of good cholesterol, however physical activity can also boost your HDL cholesterol without the need for a glass of wine.

Drinking alcoholic beverages is both a tonic and a poison. Light-to-moderate alcohol consumption is typically safe but given the complex nature of the effects of alcohol on the body and the complexity of people who drink it, alcohol intake guidance should ideally be tailored.

Treatment for alcohol use disorder

Alcohol can have an impact on every system in the body causing health problems throughout the body: cardiovascular disease, liver disease, immune system problems, cancer, ulcers, and disturbance of the gastrointestinal system. Many of these problems can lead to life-threatening outcomes.

The treatment of alcohol dependency involves a variety of different methods. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute of Health (NIH) are both trusted sources you can access to get help for yourself or a loved one. A combination of medical advice from a health care provider, social, and family support is also essential.

Trintellix and alcohol: can they be used together?

Trintellix is a brand-name drug containing the active drug vortioxetine. It is an FDA-approved prescription medication used to treat the symptoms of a type of depression known as Major Depressive Disorder (MDD). Trintellix works in a unique way that doesn’t fit neatly into other antidepressant classes but has effects similar to selective serotonin reuptake inhibitors (SSRI). Trintellix is only used to treat major depressive disorder. It is not used to treat anxiety, attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), or bipolar disorder.

Taking Trintellix and drinking alcohol together is strongly discouraged by healthcare professionals. Both work on slowing down the central nervous system causing drowsiness, sedation, and impairment. When taken together however they can create health problems for you, impact your mental health further, cause challenges in your home life with loved ones, and other serious concerns. In the US, 13.8 million people received treatment for depression in 2020. Due to how commonly they’re used people tend to forget that antidepressants can have dangerous side effects and interactions with alcohol. Read on to find out how drinking alcohol can make symptoms of depression more severe and harder to treat when taking Trintellix.

What are the different types of antidepressants?

There are various classes of antidepressant medication. Below are the main ones:

Selective Serotonin Reuptake Inhibitors (SSRIs)

Trintellix falls into this category. Some other commonly prescribed SSRIs are Paxil (paroxetine), Prozac (fluoxetine) Lexapro (escitalopram), Zoloft (sertraline), and Celexa (citalopram).

Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)

SNRIs, work in a similar way to SSRIs. This type of antidepressant stops the brain from removing both the serotonin and norepinephrine that are released naturally. Norepinephrine enhances awareness and focus as well as allowing the brain to create and recall memories. SNRIs create a surplus of this chemical to help combat the fuzzy, distant feelings often associated with depression. Common SNRIs include, Cymbalta (duloxetine), Effexor (venlafaxine) and Pristiq (desvenlafaxine).

Monoamine oxidase inhibitors (MAOIs)

Certain alcoholic beverages contain a substance called tyramine that can cause serious side effects if consumed while on an MAOI. Side effects include a sudden dangerous increase in blood pressure. Doctors will advise you against alcohol use if you are taking an MAOI. Tyramine is also found in certain foods, so your healthcare provider will give you advice on which foods to avoid. Excessive tyramine in the body can also cause dangerously high blood pressure. Marplan (isocarboxazid), Nardil (phenelzine), and Emsam (selegiline) are commonly prescribed MAOIs. You should not use (MAOIs) with Trintellix.

Tricyclic antidepressants (TCAs)

TCAs show their greatest side effects during the first few weeks of treatment. At this point, it is not a good idea to consume alcohol. A few weeks after side effects have passed it’s generally considered safe to drink small amounts of alcohol but still not advised. Elavil (amitriptyline), Silenor (doxepin), and Pamelor (nortriptyline) are commonly prescribed TCAs.

Norepinephrine and dopamine reuptake inhibitors (NDRIs)

Drugs in this category include Wellbutrin SR and XL (bupropion).

How does Trintellix work?

It is thought Trintellix works by correcting the imbalance of serotonin. Serotonin is a neurotransmitter in the brain. Low levels of serotonin may be linked to symptoms of depression.

What are the side effects of Trintellix?

Common side effects of Trintellix include:

Mild side effects that have been reported with this drug include:

Serious side effects that have been reported with Trintellix include:

  • Risk of suicidal thoughts and behaviors in children and young adults
  • Serotonin syndrome (high levels of serotonin)

To minimize drug interactions and worsening of possible side effects you must inform your health care professional of other medical conditions you are taking prescription drugs to treat, over-the-counter medications or supplements such as St.John’s Wort. If you are breastfeeding and taking Trintellix, talk with your doctor about the potential risks and benefits. This article is not medical advice therefore always speak to your doctor about your health conditions.

Can you mix Trintellix and alcohol?

Trintellix’s prescribing information does not list alcohol as a contraindication or warning but is strongly discouraged by healthcare professionals. Trintellix can worsen the effects of alcohol, while alcohol can worsen the side effects of Trintellix. When you have depression, you have an increased risk of developing a substance use disorder. Therefore mixing antidepressants with alcohol can lead to alcohol abuse, increasing the potential to become alcohol dependent. If you drink and develop an addiction to alcohol, it will become more difficult for you to control your symptoms of depression and get your alcohol consumption under control. You may need more frequent and long-term treatment if you have both an alcohol use disorder and depression.

The combination of alcohol and antidepressants can be very challenging if someone is drinking, binge drinking, heavy drinking, or has an alcohol use disorder prior to taking antidepressants. Furthermore, if someone decides to stop taking drugs for depression and starts drinking alcohol for symptom management instead, they can worsen their symptoms of depression, in some cases leading to suicidal thoughts.

ADHD and alcohol

Research has shown there is a powerful link between attention deficit hyperactivity disorder (ADHD), alcohol misuse, and substance use disorders. If you have a diagnosis of both ADHD and alcohol use disorder, this is known as a co-occurring disorder. In 2019 8.8% of US children were diagnosed with ADHD. A Centers for Disease Control and Prevention report described ADHD diagnosis as the most prevalent among children aged 3-17 years. It usually begins in childhood, and often continues through adolescence into early adulthood and beyond. Adult ADHD figures in the US are estimated to be 2.5% by The American Psychiatric Association.

In this guide, we will discuss these links, how alcohol affects people with ADHD, its treatment, and how alcohol interacts with ADHD medications.

What causes ADHD?

ADHD can be caused by your genes. Parents and siblings of ADHD children are on average 4-5 times more likely to have the disorder than the general population. Research shows there is a reduction in dopamine involved in some chemical pathways in the brain in ADHD patients. Dopamine is a chemical that influences our behavior, encouraging our brain cells to take certain actions.

Some symptoms of ADHD:

  • Inattention
  • Poor decision making
  • Poor impulse control
  • Easily distracted
  • Interrupting
  • Frequent mood swings

How do we treat ADHD?

Short-acting central nervous system stimulant medications such as Adderall and Ritalin, as well as intermediate and long-acting stimulant medications such as  Vyvanse, Mydayis, Focalin XR and Concerta, reduce the symptoms of ADHD to make the condition much less of a daily problem. By working on the central nervous system they increase activity in areas of the brain that help with concentration and behavior. They work specifically on the brain chemicals dopamine and norepinephrine. Dopamine in particular is involved in allowing you to feel pleasure, focus, and find things interesting.

Treatment for ADHD is commonly arranged by a specialist in the psychiatry department. Non-medication treatment programs involving cognitive behavioral therapy and psychological counseling are also an option.

How does alcohol affect the brain in comparison to ADHD medication?

Alcohol has the opposite effect as a stimulant. It decreases central nervous system activity i.e. it is a depressant. Logic may make us think these drugs cancel each other’s effects. However, alcohol changes how your body processes ADHD medication when taken together leading to adverse side effects.

Stimulants will mask the effects of alcohol, causing you to drink more than you would regularly, even leading to binge drinking. While those struggling with ADHD may expect it to help them relax and tone down their hyperactivity, it often has the opposite effect. Additionally, alcohol’s effect on thinking, memory, and behavior is enhanced when a person has ADHD.

Why are people with ADHD more likely to abuse substances?

Drug use and increased alcohol consumption are seen to be common behaviors used as a means of self-medication to help ease the symptoms of ADHD. In the short term, alcohol abuse may solve your problems but this often leads to alcohol addiction causing a much greater issue. Teens and adults with ADHD often turn to substances during their teenage years.

Research data taken from 2005-2011 showed that in adolescents aged 12-17 years – 4.7% had an illicit drug use disorder and 4.2% had an alcohol use disorder in the past year.

Substance abuse allows sufferers to calm their thoughts so that they may better concentrate. They are more likely to overindulge in drugs or alcohol, without properly considering the consequences of doing so. Taking drugs and drinking alcohol may allow them to fit in with friends and colleagues.

Higher rates of comorbidities such as mental health conditions, alcohol dependence, and drug abuse are seen in people with ADHD developing in early adulthood.

Where to get help?

If you or your loved one has ADHD and is struggling with substance abuse talk to your healthcare provider. Get support, your doctor can help you make decisions that reduce your risk of misusing substances.

The National Institute on Drug Abuse is an online resource available for you or someone you are concerned about.

Diabetic Glucose Test Strips: Uses and Costs

According to the American Diabetes Association self-monitoring of blood glucose is the key to diabetes management. They recommend that you check your blood glucose roughly 6 to 10 times per day at the following times: before meals and snacks, at bedtime, occasionally after meals, before exercise, when low blood glucose is suspected, after treating low blood glucose until normal levels are reached and before critical tasks! That’s a minimum of 180 strips a month! The truth is diabetes costs money.

Did you know that in the US 38% of people with diabetes have rationed blood glucose testing supplies? Have you spent hundreds of dollars on blood glucose test strips to keep a close eye on your blood glucose levels? We know diabetic test strips are an essential tool in your diabetes care but why are they so expensive! Shopping around is the best way.

Fingerstick glucose meters with test strips are still mostly used to track blood sugar levels, although an increasing number of people with diabetes are now using continuous blood glucose monitors. For answers to questions about the costs, types of tests strips available, and more read on.

What are glucose test strips used for?

As a diabetic, you know that keeping your blood glucose levels under tight control undoubtedly reduces the chance of developing complications of diabetes. Meters and strips are essential medical supplies that are part of your diabetes management to give you an immediate reading of your blood sugar levels.

To take a blood sugar reading, you use a device called a lancet needle to poke your finger to draw a drop of blood. You then apply the drop of blood to a test strip which you then insert into the meter. Most meters produce a reading on the spot. The meter can also store results for later review by you and your doctor.

How do glucose test strips work?

The science behind how blood sugar test strips work is complicated but can be explained in simple terms. The chemicals in the strip (an enzyme and a mediator) react with glucose in your blood to create an electric current, causing electrons to travel to the meter. The meter determines how much glucose was required to generate that much electricity, and uses this to give your blood glucose number on the meter screen!

You simply insert a glucose test strip into the blood glucose meter brand they are designed for. Using a lancing device take your blood sample and place it on the end of the strip where a tiny sensor is enclosed to get a reading. Differences in strip brands are found in the amount of blood required, time to result, and cost.

You must also remember to carry out quality control checks of your blood glucose meter on a regular basis. You use a control solution to make sure the test strips and meter are working properly together.

Are blood glucose test strips covered by insurance?

Test strips are covered by most health insurers, as well as Medicare. But even with this coverage, test strips can often be very pricey, particularly if you have a high deductible health plan. This type of plan might need to pay over-the-counter prices for supplies until you meet the deductible. Your insurance might not cover the brand of test strips that you want. Many insurance plans specify the brands of meters and test strips you can choose from. That means brands not offered will cost much more.

You may need a specific meter that transmits readings to your insulin pump, or you may have switched insurance plans and don’t like the meters and strips covered by their new plans. There is a possible way around this. Your doctor might be able to help you get coverage for diabetes supplies by writing a Letter of Medical Necessity to the insurance company outlining your reasons for the specific request.

Where can I buy diabetic test strips?

You can buy glucose test strips over the counter in the US at independent retail pharmacies, Walmart or online from Amazon or eBay to name a few places.

How much do diabetic test strips cost?

The costs can vary dramatically, and they can add up, especially if you buy them without insurance. Prices change frequently due to offers or bulk buying of strips. To give you a rough idea of the price range, at the time of publication, Walmart showed the following brands at these comparative costs:

Contour Next test strips

  • For use with the range of CONTOUR NEXT blood glucose meters.
  • Only requires a tiny 0.6 microliters blood sample
  • 5-second result
  • 100 test strips $37.18

Freestyle lite test strips

  • For use only with FreeStyle Lite and Freestyle Freedom Lite Sytems
  • Blood sample of 0.3 microliters to perform the test
  • 60-second resample window
  • 100 test strips $48.00

Freestyle test strips

  • For use with FreeStyle (also known as FreeStyle 3 and FreeStyle 5), FreeStyle Flash, and FreeStyle Freedom m
  • Small blood sample size, only 0.3 microliter
  • Fast, 5-second average test time
  • 100 test strips $61.96

Accu-chek Aviva Plus test strips

  • For use with Accu-chek Aviva, Accu-chek Aviva Connect, Accu-chek Aviva Combo and Accu-chek Aviva Expert
  • 0.6 microliter blood sample
  • 100 test strips $49.83

Accu-chek smartview test strips

  • For use with Accu-chek Guide and Accu-chek Guide Me
  • less than 4-second test
  • 100 test strips $84.98

True Metrix blood glucose test strips

  • For use with True Metrix, True Metrix Air and True Metrix Go
  • A small blood sample, as little as 0. 5 microliters
  • 100 test strips $24.00

True track test strips

  • For use with Truetrack meter
  • 100 test strips $20.98

Onetouch Verio diabetic test strips

  • Suitable for use with One-Touch Verio Glucose Test meters
  • Requires just a tiny 0.4 microliter blood sample
  • Results in just 5 seconds
  • 100 test strips $49.66

One-Touch Ultra test strips

  • Compatible only with the OneTouch Ultra2 and OneTouch UltraMini meters (OneTouch Verio meters have their own brand of strips)
  • Requires just a tiny 0.4 microliter blood sample
  • Results in 5 seconds
  • 100 test strips $50.94

Accu-chek guide test strips

  • Compatible with all three Accu-Chek Guide meter models only (Accu-Chek Aviva and SmartView meters have their own specific strips)
  • Requires 0.6 microliter blood sample
  • Results in under 4 seconds
  • 100 test strips $34.94

ReliOn Premier test strips

  • Compatible with all ReliOn meter models
  • Requires small 0.5 microliter blood sample size
  • Results in 7 seconds
  • Allows fingertip or palm testing
  • 100 test strips $17.88

Prodigy test strips

  • Compatible with all Prodigy meter models: Voice, Pocket, and AutoCode
  • Need 0.7 microliter blood sample
  • Results in 7 seconds
  • Approved for alternate site testing (beyond just fingertips)
  • 100 test strips $13.45

Bayer Contour Next test strips 

  • Compatible with all Contour Next glucose meter models
  • Requires 0.6 microliter blood sample
  • Results in 5 seconds
  • Allows second-chance sampling
  • 100 test strips $37.18

Ketone test strips

  • A range of many different brands  e.g. ReliOn ketone test strips
  • 50 test strips $6.64

Concerta and alcohol: can they be used together?

Research has shown there is a powerful link between attention deficit hyperactivity disorder (ADHD), alcohol abuse, and substance use disorders. In 2019 8.8% of US children were diagnosed with ADHD. Adult ADHD figures in the US are estimated to be 2.5% by The American Psychiatric Association. Concerta is a commonly prescribed stimulant drug used to treat ADHD. Medical advice is not to combine Concerta with alcohol. Read on to find out why.

What is Concerta?

Concerta is the brand name of an extended-release form of methylphenidate. Methylphenidate is a central nervous system (CNS) stimulant that is classified as a Schedule II controlled substance. It is a long-acting stimulant, therefore you only need to take Concerta once daily for symptom relief.

Concerta treats the symptoms of ADHD such as inattention, poor decision making, and poor impulse control. It can also be used for the treatment of narcolepsy. By working on the central nervous system, Concerta increases activity in areas of your brain that help with concentration and behavior. It works specifically on the brain neurotransmitters dopamine and norepinephrine. Dopamine in particular is involved in allowing you to feel pleasure, focus, and find things interesting. Other prescription drug stimulants include Adderall and Ritalin.

What causes ADHD?

ADHD can be caused by your genes. Parents and siblings of ADHD children are on average 4-5 times more likely to have the disorder than the general population. Research shows there is a reduction in dopamine involved in some chemical pathways in the brain in ADHD patients. Dopamine is a chemical that influences our behavior, encouraging our brain cells to take certain actions.

How do we treat ADHD?

Treatment for ADHD is commonly arranged by a specialist in the psychiatry department. A prescription stimulant like Concerta is commonly started to treat symptoms. Non-medication treatment programs involving cognitive behavioral therapy and psychological counseling are also an option.

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How does taking Concerta and drinking alcohol at the same time affect you?

Alcohol has the opposite effect as a stimulant like Concerta. It decreases central nervous system activity i.e. it is a depressant. Logic may make us think these drugs cancel each other’s effects. However, alcohol changes how your body processes ADHD medication when taken together, leading to adverse side effects.

Stimulants will mask the effects of alcohol, causing you to drink more than you would regularly, even leading to binge drinking or alcohol poisoning. While those struggling with ADHD may expect it to help them relax and tone down their hyperactivity, it often has the opposite effect. Additionally, alcohol’s effect on thinking, memory, and behavior is enhanced when a person has ADHD.

Mixing methylphenidate with alcohol can have a wide range of cognitive and physical effects:

  • Changes in blood pressure
  • Changes in heart rate
  • Changes in reaction times
  • Lack of attention/focus
  • Impulsivity is heightened
  • Increased drowsiness
  • Judgment hampered
  • Increase of blackouts

The long term effects of taking Concerta with alcohol can include:

  • Organ harm, such as liver damage, and kidney failure
  • Cardiovascular problems such as high blood pressure, erratic heart rate, and heart attack

Why Are People With ADHD more likely to abuse substances?

Drug use and increased alcohol consumption are seen to be common behaviors used as a means of self-medication to help ease the symptoms of ADHD. In the short term, alcohol may solve your problems but this often leads to alcohol addiction causing a much greater issue. Teens and adults with ADHD often turn to substances during their teenage years.

Substance abuse allows sufferers to calm their thoughts so that they may better concentrate. They are more likely to overindulge in drugs or alcohol, without properly considering the consequences of doing so. Taking drugs and drinking alcohol may allow them to fit in with friends and colleagues.

Higher rates of comorbidities such as mental health conditions, alcohol dependence, and drug abuse are seen in people with ADHD. This normally develops in early adulthood. Approximately one-third of college students have abused stimulants like Concerta.

Where to get help?

Inpatient alcohol detox and rehab is normally the first step in recovery. Symptoms of ADHD and alcohol withdrawal symptoms can be difficult to cope with without medical supervision, therefore many people seek an inpatient treatment facility. Outpatient care is also an option that requires extra support from your loved ones. Many interventions and treatment options can be put in place to help improve your quality of life. Group therapy with friends, family members, or others in the same position as you and cognitive behavioral therapy are to name a few.

If you are worried about yourself or a loved one some of the following resources may be of help to you – SAMHSA – Substance Abuse and Mental Health Service or The National Institute of Mental HealthSAMHSA also provides a helpline. Your doctor or healthcare provider can also help you make decisions about your addiction treatment and advise in choosing a treatment center.

The Elder Fraud Report

The patterns and changes in fraud committed against elders

While the majority of us believe that we should look after the most vulnerable members of society, there are some who prey on those vulnerabilities for their own gain. There are many costs associated with later life, from prescription medications to treating the grandchildren, but losing money to fraud and scams shouldn’t be one of them.

Popular YouTube channels and videos featuring pranksters wasting the time of would-bescammers may have had a hand in the increase in awareness of fraud and scams which target the over 60s in particular. In fact, the term ‘elder fraud’ saw a substantial increase insearches in 2021 with 6,120 searches in the US, compared to 4,620 in the previous year; a rise of 32%.

What is elder fraud?

There are a number of types of elder fraud and targeted scams that can con people out of their money, with millions of elderly US citizens falling victim to it each year.

With the ever-evolving world of technology being somewhat confusing and intimidating for many elderly citizens, some may be more susceptible to falling victim to scams that involve technology.

From extortion to romance scams, there are numerous ways in which fraudsters target the elderly, many of which we will explore in this report, as well as the losses and prevalence of these frauds.

 

The states where elder fraud is most prevalent

Most prevalent elder fraud

Some states seem to have to deal with elder fraud more often than others, with there being thousands of incidents in each state during 2020. So, with this in mind, which states had the highest rate of elder fraud?

⦁ California – 12,534 victims
While California is known as the Golden State and is the home to the glitz and glamour of Hollywood, it is also the state with the largest number of elder fraud victims with more than 12,500 victims in the year of 2020.

⦁ Florida – 9,252 victims
From the Golden State to the Sunshine State, Florida is known for its aging population and sadly, this population is particularly vulnerable to fraud and scam attempts. With over 9,000 victims over the age of 60, Florida ranks second in terms of elder fraud prevalence.

⦁ Texas – 6,342 victims
The southern state of Texas ranks in third position in terms of states where elder fraud is most prevalent, with more than 6,000 victims during 2020.

 

The states where elder fraud is most costly

Most costly elder fraud

⦁ California – $152.64 million
As the state with the highest number of elder fraud victims, it is no surprise to see California sitting at the top of the table of states with the costliest elder fraud. At more than $152.6 million in financial losses, that equates to an average of $12,178 per victim.

⦁ Florida – $84.65 million
Following the pattern, Florida takes the second spot with elderly residents losing a huge $84.6 million during 2020. If we break this down between the 9,252 victims, that’s an average of $9,149 per person.

⦁ Texas – $69.76 million
Again, just as before, in third place is the state of Texas which saw a loss of $69.8 million, equating to an average loss of $11,000 per victim.

The most common types of elder fraud

Common types elder fraud

There are many ways in which elderly people are defrauded and scammed out of their hard-earned money, but which are the most common types?

⦁ Extortion – 23,100 victims
Sadly, the most common type of elder fraud is extortion, a method that involves the threat of harm, either physical or financial, or else threatening the release of sensitive data. Many of these extortion threats were committed via email, with a specific email extortion campaign taking place in 2020, threatening to infect the victim with COVID if they did not pay a set amount in cryptocurrency.

⦁ Non-payment/non-delivery – 14,534 victims
With so many of us having to rely on online shops and grocery deliveries made through online orders, the over 60s were getting online more than ever before during 2020. Unfortunately, this may have contributed to the large number of non-payment/non-delivery fraud victims, a fraud type that involves offering and advertising an item for sale with no intention of sending the item ordered when payment is made.

⦁ Tech support – 9,429 victims
If you have watched videos of pranksters wasting the time of fraudsters, it’s likely that you have witnessed a would-be tech support fraudster. This involves fraudsters posing as technical support workers, often claiming that the victim has a computer virus or that their online banking has been compromised. These scams often end with the victim unwittingly transferring money to the fraudster or even handing over online banking details.

The most costly types of elder fraud

Costly types of elder fraud

Each different type of elder fraud can cost victims millions of dollars every year, but which type of fraud has cost over 60s the most in 2020?

⦁ Confidence fraud/romance – $281.1 million
Playing on the vulnerabilities and even the good nature of the elderly victims, confidence fraud and romance scams use personal relationships to secure payments and even fraudulent investments. These relationships may involve the criminal impersonating a loved one or may involve them creating an online persona to win the trust of a victim. These scams cost victims a huge $281.1 million, equating to an average loss of $41,240 per victim.

⦁ BEC/EAC – $168.8 million
Business email compromise/email account compromise, otherwise known as BEC/EAC targets businesses and individuals respectively, fraudulently accessing email accounts and using them to transfer funds from the victim. With a total cost of $168.8 million during 2020, that equates to an average loss of $47,817 per victim.

⦁ Tech Support – $116.4 million
Tech support scams are particularly effective against elderly people as technology can often be intimidating for those of a mature age. Receiving a phone call to tell them that their laptop has a virus or they need to pay to update software can be confusing, so it’s no surprise that so much money is lost to these scams each year, with an average loss of $12,346 per victim in 2020.

Methodology:

All data is taken from a 2020 Elder Fraud Report produced by the Federal Bureau of Investigation.

Search volume was taken from Google Keywords Planner and relates to searches conducted in the United States in 2020 and 2021.

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Xarelto and alcohol: can they be used together?

A common question many people ask is can Xarelto and alcohol be used together? Xarelto (rivaroxaban) has been known as a simple and convenient drug you can take after a meal or snack. Does the same apply to drinks, in particular to alcohol? The official line from Janssen Pharmaceuticals, the Xarelto website, and the FDA is that patients do not need to change their dietary habits while taking this drug. So, in an ideal world, there’s no harm to drink alcohol while taking Xarelto. Its mechanism of action isn’t affected by alcohol consumption. This may be the case but in the real world, healthcare professionals recommend against alcohol consumption with Xarelto. Read on to find the reasons why. Firstly let’s give you a quick re-cap on what Xarelto is and how it works.

What is Xarelto and how does it work?

Xarelto is a blood thinner that treats and helps prevent blood clots that are related to certain conditions involving the heart and blood vessels. It is used to treat some of the following conditions:

The blood clotting process involves a range of different components such as platelets and clotting factors, these factors are named and numbered and all play an important role. The blood clotting process is essential when you’re injured. Sometimes, however, a blood clot can appear in an artery that supplies your heart, brain, or lungs or a deep vein in the lower leg. When a clot blocks blood flow to your heart, it can cause a heart attack. If it blocks the blood flow to your brain, it can cause a stroke. The use of blood thinners in this group of patients is common.

Xarelto stops blood clots from forming and getting larger by blocking Factor Xa in the blood clotting process. Xarelto is a new kind of oral anticoagulant that does not require routine blood tests, unlike older drugs like warfarin (Coumadin).

Why is it important to avoid alcohol while taking Xarelto?

Research shows that small quantities of alcohol may have anticoagulant properties, working almost like blood thinners. Ethanol the scientific name for alcohol has been found to reduce levels of fibrinogen, another protein involved in blood clotting. A study published in 2015 found that drinking 2-3 alcoholic drinks a day reduced the amount of fibrinogen in the blood by 14%. So if we combine both Xarelto and alcohol it may result in an intensified anticoagulant activity in your blood.

Why is this dangerous? Alcohol and Xarelto are blood thinners and when both are combined the risk of side effects increases, in particular, higher risk of minor to major bleeding problems.

Minor bleeding such as nosebleeds, bruising and bleeding gums may occur. Major bleeding events such as menstrual bleeding that is heavier than normal, coughing up blood, and severe headaches are possible too. Internal bleeding is the most dangerous because it is more difficult to detect and life-threatening.

You may have a higher risk of bleeding if you also take some of these drugs:

  • NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen
  • Aspirin or aspirin-containing products
  • Warfarin (Coumadin)
  • Drugs containing heparin
  • Other blood-thinning drugs

How much alcohol is safe to drink with Xarelto?

Your alcohol intake has differing effects on the body depending on how much is consumed with blood-thinning medications:

  • Occasional drinking with Xarelto does not put you at significant risk and does not appear to interfere with what Xarelto does.
  • In people who drink moderately, the effect of alcohol on platelets in the body is short-lived.

According to The U.S. Dietary Guidelines for American adults, moderate drinking is classed as follows:

  • For women – up to one drink per day
  • For men – up to two drinks per day

Exceeding the recommended guidelines of alcohol use is considered heavy drinking, and an excessive amount of alcohol (binge drinking) with Xarelto may result in extreme blood-thinning due to the combined effect.

Best type of insulin pumps

Insulin pumps are part of the rapid progression in diabetes management. In 2019 a review found over 350,000 people in the United States were using insulin pump therapy (also known as continuous subcutaneous insulin infusion (CSII) to control their diabetes. New technology to manage your diabetes can be overwhelming! Maybe you’ve just started using your insulin pump and you’re still getting to grips with your equipment and have some unanswered questions. Maybe you are in the early stages of considering an insulin pump. One area of confusion is what type of insulin is used in which pump.

How does insulin work?

The most important hormone to understand in diabetes is insulin. It is made in your pancreas which is located just behind your stomach.

Without getting too medical let’s look at how insulin works. Insulin travels in your blood through your body. It opens up cells in your body so that glucose can enter them. After glucose enters cells, the cells immediately use it for energy in the form of glycogen or convert it to fat for use later. When glucose leaves your blood and enters cells, your blood glucose level falls. Your pancreas detects your glucose falling and turns off the release of insulin. This stops your blood sugar from going too low and causing hypoglycemia. At the same time, your liver begins to make more glucose in your blood.

This whole system keeps your glucose levels correct. Insulin is the only means that the body has of lowering blood glucose levels. When this system fails diabetes occurs. Each type of diabetes involves the pancreas not functioning properly.

When you have type 1 diabetes the only choice of medication is insulin. If you have type 2 diabetes you may use insulin injections if diet and tablets are not working for you. Insulin pumps are an option for both types of diabetes.

How does insulin for pumps work?

The job of an insulin pump is to provide continuous delivery of insulin all day long. An insulin pump can replace your daily injections or long-acting insulin injections. This is because an insulin pump releases insulin when the body needs it, it works like a human pancreas. The settings on a pump allow the doses of insulin to be adjusted therefore you can tailor your insulin delivery.

A rapid-acting insulin is used in insulin pumps, occasionally Regular insulin. Rapid-acting insulin types are aspart (NovoLog), lispro (Humalog), and glulisine (Apidra). The reason for using short-acting insulin is that the pump can deliver a steady amount of insulin called basal insulin all day long. In addition at mealtimes, a bolus amount of insulin can be easily delivered with just a push of a button.

Let us look at the terms basal insulin and bolus insulin in more depth to understand how the insulin pump works to treat your diabetes.

Basal

The rate at which insulin slowly enters your body is called the basal rate. Basal insulin is given to you continuously throughout the day and night. Your basal insulin is usually a small amount and can vary depending on your needs e.g. physical activity. You determine your individual basal rates by measuring your blood sugar levels with a blood glucose meter. Most people check their blood sugar at least four times a day or may use a continuous glucose monitor (CGM). Many insurance companies require you to take readings four times a day as a policy.

Bolus

At mealtimes, you can push a button to deliver extra insulin called a bolus dose. You determine this amount by using your blood glucose reading and the amount of carbohydrate you plan on eating. Your Diabetes Care and Education Specialist will help you with calculating insulin doses and the amounts of boluses based on your carbohydrate intake, and how to set the pump. Sounds like too many calculations? Most pumps also have a bolus calculator function to help you.

Final word

We hope this blog has provided you with an answer to what type of insulin goes into an insulin pump and helps clear up any confusion. Remember your healthcare team is there to help and guide you with your insulin pump. You will need hands-on training from your healthcare team to operate your pump. You will be taught how to fill a pump reservoir, prime tubing, select an infusion site, change an infusion set, disconnect the device, calculate and program insulin doses, fix potential problems, create backup plans in case of pump failure, and prevent diabetic ketoacidosis.

What type of insulin goes into an insulin pump?

Do you have diabetes and are curious about insulin pumps? Are you struggling with daily injections? You can’t get your blood sugar levels to the correct level? Insulin pumps can offer lifestyle freedom and flexibility, so it’s no surprise you want to know more. There are many types of insulin pump brands on the market that can cause confusion. Read on to find out about the different types of insulin pumps available and the pros and cons of using pumps. You can use this information to talk with your healthcare provider, or your Diabetes Care and Education Specialist to work out which option is right for you.

Why are insulin pumps used?

You can think of an insulin pump as a human pancreas supplying your body with doses of insulin. When you have type 1 diabetes the only choice of medication is insulin. If you have type 2 diabetes you may use insulin injections if diet and tablets are not working for you.

For some people and you may be one of them, an insulin pump could be just what you need to get your blood sugar levels to target and reduce episodes of hypoglycemia. These devices are as close as you can currently get to the gradual administration of rapid-acting insulin that is normally taking place in the body. Insulin pump therapy may be the answer for patients who can not achieve good blood glucose levels with syringes, insulin pens, or insulin jet injectors.

How does an insulin pump work?

All pumps look like a small device about the size of a mobile phone and run off batteries with an inbuilt alarm to warn you if the battery is running low. There are many insulin pump brands on the market. The one you choose will depend on various factors. Speak with your healthcare provider to figure out which option is right for you.

When you use an insulin pump to treat your diabetes two different types of insulin dosages are used:

Basal

The rate at which insulin slowly enters your body is called the basal rate. Basal insulin is given to you continuously throughout the day and night. Your basal insulin is usually a small amount and can vary depending on your needs e.g. if you are exercising. You determine your individual basal rates by measuring your blood sugar levels with a blood glucose meter. Most people check blood sugar at least four times a day, or you may use a continuous glucose monitor (CGM). Many insurance companies require you to take readings four times a day as a policy.

Bolus

At mealtimes, you can push a button to deliver extra insulin called a bolus dose. You determine this amount by carbohydrate counting. Bolus insulin is a rapid-acting insulin. Your Diabetes Care and Education Specialist will help you with calculating insulin doses and the amounts of boluses based on your carbohydrate intake, and how to set the pump. Most pumps also have a bolus calculator function to help you.

What types of insulin pumps are there?

The best type of insulin pump depends on your lifestyle. The two main options available are a traditional pump or a tubeless pump (patch pump). Both types of pumps are attached to your body by a tiny tube called a cannula. Your cannula needs to be changed every 2-3 days regardless of which type of pump you use. Additionally, it is very important you move your cannula to a different part of your body each time you use it, to prevent injection bruises and bumps.

Traditional Insulin pumps

The parts that make up a traditional insulin pump

  • Insulin reservoir (or container) with a pumping mechanism
  • Tubing to attach to the body
  • Infusion set

The pump body contains buttons that allow you to program various bits of information e.g. amount of insulin for meals, specific types of basal rates, or stop the insulin infusion. The pump itself can be carried on your belt or pocket. If you want to hide it you can wear it under your clothes.

Insulin patch pumps

These are worn directly on the body and attached with an adhesive patch. Inside is a small case that contains a reservoir pumping mechanism, and an infusion set that is attached to a site on the body e.g. abdominal, leg, or arm. Patch pumps have no extra tubing which means the pump sits directly on your skin. It is controlled wirelessly by a separate device that allows the programming of insulin delivery.

Here are some examples of commonly used FDA approved insulin pumps:

  • Medtronic: Medtronic offers the Minimed 770G system (approved for type 1 diabetes for ages 2 and older) and the Minimed 630G system (approved for both type 1 and type 2 diabetes for ages 14 and older)
  • Omnipod: The Omnipod DASH system can be used by children and adults for both type 1 and type 2 diabetes
  • Tandem: Tandem makes the t:slim X2 insulin pump. This pump is intended for people with type 1 diabetes who are ages 6 and older

The pros and cons of insulin pumps

Pros

  • It often smoothes out the swings of glucose during the day because the insulin is administered slowly and in small doses
  • It is flexible because you can take the bolus dose just before a meal
  • You do not need to take daily injections
  • You can rapidly disconnect and reconnect the pump to take a shower or swim but it can take a little getting used to when worn to bed
  • It’s safe from overdosage because it has built-in proactive devices to prevent this from happening

Cons

  • Infections of the skin are possible because the infusion set is left in place for several days
  • Frequent testing of blood glucose is essential, at least four times a day (unless your pump has an inbuilt system for testing)
  • Only short-acting insulin is used in the pump so if insulin stops you may enter ketoacidosis rapidly
  • You may be allergic to the tape that holds the infusion set onto the skin
  • Commitment, time, and training is needed to use your pump correctly

Diabetes technology is a great way forward in diabetes management but requires a lot of time and effort, to begin with, and using a pump is definitely not a treatment to do on your own at the beginning. The American Diabetes Association state the one requirement for using a pump is that you and your caregivers are ready and willing to do what it takes to use the pump safely. You will need hands-on training from your diabetes care team. You will be taught how to fill a pump reservoir, prime tubing, select an infusion site, change an infusion set, disconnect the device, calculate and program insulin doses, fix potential problems, create backup plans in case of pump failure, and prevent diabetic ketoacidosis.

How to make Vyvanse last longer

Centers for Disease Control and Prevention report described ADHD diagnosis as most prevalent among children aged 3-17 years. It usually begins in childhood, and often continues through adolescence into early adulthood and beyond. Adult ADHD figures in the US are estimated to be 2.5% by The American Psychiatric Association.

Vyvanse is a commonly prescribed prescription medication used for the treatment of ADHD. As a controlled substance, doctors usually prescribe small doses of it. The effects of Vyvanse wear off over time and many patients search for ways to intensify Vyvanse throughout the day. You shouldn’t try to intensify the effect of Vyvanse on your body. Misuse of Vyvanse can have serious side effects, including heart problems and changes in heart rate.

What is Vyvanse?

Vyvanse is the brand name of lisdexamfetamine dimesylate, a derivative of amphetamine.  It is a prescription drug belonging to a class of drugs known as Central Nervous System stimulants. It is FDA approved to treat symptoms of Attention Deficit Hyperactivity Disorder (ADHD) and moderate to severe binge eating disorder. Vyvanse is not for weight loss. Vyvanse is a prescription stimulant medication but is also classed as a Schedule II controlled substance. As a controlled substance, doctors usually prescribe small doses.

Other drugs included in the class of Central Nervous System stimulants include Adderall XR, Concerta (methylphenidate), and Ritalin. Vyvanse treats ADHD and binge eating disorders by increasing norepinephrine and dopamine levels, thereby altering the balance of chemicals in your brain.

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How does Vyvanse work?

By working on the central nervous system Vyvanse increases activity in areas of the brain that help you with your concentration and behavior. It works specifically on the brain chemicals dopamine and norepinephrine. Dopamine in particular is involved in allowing you to feel pleasure, focus, and find things interesting. Stimulant medications reduce the symptoms of ADHD to make the condition much less of a daily problem such as inattention, poor decision making, and poor impulse control.

The most common side effects in adults taking Vyvanse are decreased appetite, dry mouth, and trouble sleeping. More severe side effects of Vyvanse are cardiovascular problems, such as a fast heart rate, increased blood pressure, or in rare cases, chest pain or heart attack.

How long does Vyvanse last in your system?

Vyvanse has the stimulant amphetamine but it also has a compound called lysine. Your body will need to absorb the lysine to reach the stimulant so the effects of Vyvanse can stay in your system for up to 14 hours.  The exact duration of action may vary from person to person, depending on factors such as age, weight, and how well the medication is tolerated. Vyvanse is typically taken once daily in the morning. It is important to take Vyvanse at the same time each day to maintain an even level of medication in the body.

Following the discontinuation of the medication, it will take up to 3 days before Vyvanse is cleared completely from your system. How long Vyvanse lasts in your system depends on factors such as your age, weight, or other medications you may be taking. If you suddenly stop taking Vyvanse, you may get withdrawal symptoms (also known as the Vyvanse crash) such as anxiety, irritability, and fatigue.

Treatment for ADHD is commonly arranged by a specialist in the psychiatry department. You should always consult your healthcare provider when starting, stopping, or changing your dose.

How long does it take for Vyvanse to work and reach its maximum effect in your system?

It will take about 3.5 hours for Vyvanse to work when taken on an empty stomach to reach its maximum level in your blood. If a Vyvanse chewable tablet is taken on an empty stomach it will take slightly longer to kick in.

For Vyvanse to start working in your body, lisdexamfetamine must react with your blood and be converted into the active drug dextroamphetamine. Vyvanse is a prodrug, meaning it is converted from an inactive form into an active form in your body by chemicals or enzymes.

The recommended starting dose of Vyvanse is 30 mg. Your doctor may periodically increase or decrease your dosage to help control ADHD symptoms and manage any side effects. You’ll work with your doctor to find an ADHD dose that’s best for you.

Vyvanse is a available in chewable tablet form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg & 60 mg.

Vyvanse is also available in capsule form in the following doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg & 70 mg.

Taking selective serotonin reuptake inhibitors (SSRIs) with Vyvanse may increase the risk of a rare condition called serotonin syndrome, which can cause death.

How to make Vyvanse last longer?

A commonly searched question is how to intensify Vyvanse or how to make Vyvanse last longer. An alternative way to look at the question would be to think about what you could do to improve the performance of the drug, here are some ways:

  • Exercise in any form e.g. walking the dog, taking a brisk walk, or weight training, will most certainly help to eliminate symptoms of depression and to make the effects of the medication last longer. It is scientifically proven that exercise can reduce depression and anxiety, alongside boosting your mood
  • Eliminate Vitamin C (also known as ascorbic acid) products from your diet e.g. grapefruit juice, oranges, and orange juice. Vitamin C delays the time it takes the body to absorb and convert Vyvanse into its active form
  • Remove any dairy or coffee-related food or liquid from your diet. This can influence the performance of the drug
  • Check your drug interactions. Speak to your pharmacist about the selection of drugs you take for other medical conditions. In particular, the interaction of Vyvanse and any other antidepressants e.g. monoamine oxidase inhibitors (MAOIs) can cause an increase in blood pressure
  • Combining magnesium supplements and ginkgo may help in intensifying Vyvanse
  • Increase the amount of protein in your diet, this can boost brain chemicals. Protein-rich foods help produce important neurotransmitters in preventing and treating depression and anxiety

How can I make Vyvanse work better?

Here are a few ways to make Vyvanse work better for you:

  • Working out the right dose for you. Speak to your doctor for medical advice to determine the best dose for you. You may need a higher dose. ADHD medications can be very effective when you find the right dosage. A good measure is to track your impulse control on various doses
  • Ask family and friends for an honest opinion on improvement or deterioration in your focus, concentration, and overall condition
  • Make changes in your lifestyle and approach to situations. Work with a mental health professional to help you manage your problems and about how you feel, think, and act. Simple steps such as leaving early for appointments to avoid the worry of arriving late or using a calendar to plan your week are useful ways to manage your ADHD

Ozempic and alcohol: can they be used together?

Surprisingly, it is extremely difficult to predict what effect Ozempic and drinking alcohol will have on an individual because of their own unique genetic makeup and tolerance levels. However, it is strongly recommended by healthcare professionals to avoid alcohol if you have type 1 diabetes or type 2 diabetes. Moderate amounts of alcohol may cause blood sugar to rise (hyperglycemia) but excessive alcohol can actually decrease your blood sugar levels (hypoglycemia).

If you are a diabetic with poorly controlled blood glucose levels, drinking alcohol will cause even more complications. Read on to find out about Ozempic and alcohol.

What is Ozempic?

Ozempic is an FDA-approved prescription drug made by Novo Nordisk. It is used for the treatment of type 2 diabetes to prevent your blood sugar from rising after eating, by slowing the rate of digestion and the release of insulin in your body. This medicine is also used to lower the risk of a heart attack in type 2 diabetics.

The active ingredient in Ozempic is semaglutide and it is classed as a Glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) medication. Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers glucagon secretion by selectively binding to and activating the GLP-1 receptor.

The drug itself is injected under the skin (subcutaneous) usually once every 7 days. The injection sites are the thigh, abdomen, or upper arm. Your dosage is based on your medical condition and your response to treatment. If you miss a weekly dose and there are less than 3 days until your next scheduled dose, do not take the missed dose. The injection can be stored at room temperature or in the refrigerator.

Why have I been prescribed Ozempic?

The number of medications available to treat type 2 diabetes in particular, is long and confusing. So, why have you been given a diabetes medication such as semaglutide? It has more than likely been prescribed for you because the combination of improving diet, increasing exercise, bodyweight reduction, and metformin medication has not achieved adequate blood sugar control for you.

Ozempic is not approved for people with Type 1 diabetes and shouldn’t be taken by women who are pregnant or breastfeeding. Some of the advantages of taking Ozempic are suppression of hunger and modest weight loss which are desirable for diabetics.

Do not use Ozempic if you have a personal or family history of medullary thyroid carcinoma (thyroid tumors or thyroid cancer) or if you have Multiple Endocrine Neoplasia syndrome type 2.

Other common GLP-1 receptor agonists are:

How does alcohol affect diabetes?

Alcohol interacts with diabetes medications causing low blood sugar (hypoglycemia). When you drink alcohol your liver will choose to remove the alcohol in your body over maintaining your blood sugar level leading to hypoglycemia. Low blood sugar makes you drowsy, confused and causes difficulty walking which are also signs of being drunk. The confusion of being drunk or hypoglycemic can be very unsafe, and a low sugar episode (hypoglycemia) could go unnoticed if you are drunk. Moderate amounts of alcohol may cause blood sugar to rise but excessive alcohol can actually decrease your blood sugar levels.

Alcohol is an appetite stimulant, so you may end up eating more calories and making less positive food choices. The calorie content of alcoholic drinks can be high and the nutrient content low, leading to an increase in calorie intake and weight gain.

Alcohol can also play a part in diabetic nerve damage, diabetic eye disease, and high blood triglycerides leading to complications.

Symptoms of low blood sugar are similar to the symptoms of too much alcohol:

  • Drowsiness
  • Confusion
  • Lack of coordination
  • Passing out

In the long run, it is a sensible idea to inform friends and family about your diabetes so they do not mistake these symptoms for you simply being drunk. If you pass out those around you need to know that this is a medical emergency.

Common side effects of Ozempic

The most common side effects caused by Ozempic may include:

  • Reactions at the site of injection
  • Allergic reactions
  • Low blood sugar (hypoglycemia) causing shakiness, fast heartbeat
  • Diarrhea
  • Constipation
  • Feeling and being sick
  • Tiredness

Some serious side effects with Ozempic may include:

  • Risk of thyroid cancer. Ozempic has caused thyroid cancer in animals. It’s unclear if this drug also increases thyroid cancer risk in humans
  • Serious allergic reactions cause swelling under your skin, normally in your eyelids, lips, hands, or feet. Swelling of your mouth, tongue, or throat leading to shortness of breath

What are the most common complications of diabetes?

Hypoglycemia

In simple terms, hypoglycemia is low blood sugar (blood glucose). You need to be particularly aware of the possibility of blood sugar levels dropping if you use insulin or take sulfonylureas, eat irregularly, exercise, and drink alcohol.

Diabetic ketoacidosis complications

Frequent and prolonged high blood sugar levels can lead to diabetic ketoacidosis. Your blood becomes acidic due to the presence of ketones. This is because your cells are starved for energy and your body begins to break down fat. This causes a fruity smell on your breath and is one of the classic ways your doctor can make a diagnosis of ketoacidosis.

Diabetic kidney disease

People with diabetes tend to develop some degree of kidney problems. In the US, diabetes is the leading cause of kidney failure in adults, making up half of all new cases.

Diabetes and heart disease

Diabetes and heart disease are undoubtedly linked. As a diabetic, you are twice as likely to have heart disease or a stroke than a non-diabetic. Cardiovascular disease is the number one cause of death in people living with diabetes.

Diabetic retinopathy

Diabetic retinopathy is more complicated and less treatable than other conditions. High sugar levels can damage the smaller blood vessels which supply the retina. They become weaker and small blisters can form that eventually burst, forming hard lumps. This is a sign that the blood supply to your eye is not as good as it should be.

Can drinking alcohol cause diabetes?

Excessive alcohol intake increases your chance of developing chronic inflammation of the pancreas called pancreatitis. This condition leads to permanent damage to the pancreas and its ability to manage the production, storage, and release of insulin. Pancreatitis can harm the ability of the pancreas to secrete insulin, which can potentially lead to type-2 diabetes. However, there are several other risk factors for type 2 diabetes including, your family history, age, and ethnic background. You are also more likely to develop diabetes if you are overweight. If you’re planning to drink alcohol and you have diabetes, aim to always stay within the recommended guidelines. This is the safest way to drink alcohol.

Always speak to your healthcare provider for medical advice regarding drug interactions, taking supplements, taking over-the-counter medications, and drinking alcohol when taking Ozempic. Healthcare professionals are the most reliable and accurate source of drug information. They can also provide you with a  medication guide for each drug you take.

What is a letter of medical necessity?

Has your health insurance denied you a service? It has happened to us all. Have you been asked to provide a Letter of Medical Necessity? Is this the first time you’ve heard this term? A Letter of Medical Necessity can be used as a powerful tool to make a request to your provider for a drug, a piece of equipment, or a service of medical necessity to you. Use this blog as a guide to understand what a letter of necessity is and how to go about writing one.

What is a medical necessity letter?

A letter of medical necessity provides evidence that services or medications may be the best thing or the only thing to improve your care. A letter of medical necessity states the claim made by your doctor to treat your medical condition with a specific test or treatment. It is an instruction and a legal document that states the doctor’s clinical decision-making recommendation. The recommended treatment must be described by your licensed healthcare provider.

When do you need a medical necessity letter?

They are typically written when a doctor says you need a certain treatment, but your insurance company disputes that fact. In this case, your doctor can write a letter of medical necessity. The letter of medical necessity is your best chance at getting approved.

What are the essential components of a medical necessity letter?

There are ten main points to include when putting together a medical necessity letter:

  • Personal details of the patient including insurer and policy number
  • Physician details and identification
  • Date of most recent assessment and specific diagnosis
  • Treatment
  • Duration of treatment
  • Relevant medical history
  • Reasons/argument why this treatment is medically necessary
  • Summary
  • Signature of the physician on their letterhead
  • Supporting evidence e.g. drugs full prescribing information, progress notes

A sample letter of medical necessity

It should be written on the physician’s letterhead and it must show a powerful argument for the medical need. The template letter below will give you a guide to producing a letter.

Name of Pharmacy Director/Payer Contact/ Medical Director

Name of Health Insurance Company

Full Address and ZIP Code

Patient Name

Patient Date of Birth/ Patient Date of Diagnosis, and ICD-10-CM code

Insurance Group Number /Policy Number

Policyholder Name

Date

Dear Payer Contact Name/Medical Director

Paragraph 1 – Letter reason statement

I am writing on behalf of my patient…

State patient name and age. Include any relevant information from the patient’s medical records and diagnosis. State the product name for medical necessity and treatment rationale. Refer to any enclosures enclosed in the letter.

Paragraph 2 – Patient Medical History and Diagnosis 

This letter provides information on medical history, diagnosis, and treatment rationale…

Include a background summary of the patient’s clinical notes and history, date of diagnosis, previous therapies, current therapies, specific diagnosis, and the length of time the patient has been under physician’s care.

Paragraph 3 – Treatment rationale

This treatment is medically necessary because…

Use supporting documentation and evidence to back up the reasons behind the recommendation of medication/product or service.

Paragraph 4 – Summary/ Closing statement

Please consider coverage of…

Brief, logical final argument. Include a phone number if additional information is needed.

Thank you for your prompt attention to this matter.

Signed by Physician

Physician name printed

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Latuda and alcohol: can they be used together?

Alcohol use can make it extremely challenging to control the symptoms of schizophrenia and bipolar disorder. Studies have shown that people with these medical conditions struggle significantly more with substance abuse. Latuda can help with schizophrenia and bipolar disorder but when taken with alcohol the side effects are amplified leading to possible life-threatening situations. Medical professionals advise against mixing the two substances. Read on to gain a better understanding of why it’s not a good idea to mix the two.

What is Latuda?

Latuda is the brand name of a prescription drug called lurasidone. It belongs to a class of drugs called atypical antipsychotics and is indicated for the treatment of bipolar disorder. Atypical antipsychotics are used in adults, alone or in combination with mood stabilizer drugs such as lithium or valproate. Other antipsychotic drugs in this drug class include quetiapine (Seroquel), and aripiprazole (Abilify).

Latuda is an FDA-approved atypical antipsychotic medication to treat two mental health conditions:

  • Depressive episodes related to bipolar 1 disorder
  • Schizophrenia

The dominant symptom of bipolar I disorder is manic episodes that last 7 days which may or may not lead to hospitalization. Also, a depressive episode referred to as bipolar depression lasting typically two weeks will normally occur. These manic and depressive episodes can happen separately or at the same time.

In children, 10 years of age and older Latuda is approved to treat major depressive episodes related to bipolar depression. For this purpose, Latuda may be used alone. Studies show that antidepressants may increase the risk of suicidal thoughts and behaviors in children and young adults.

  • Schizophrenia

Schizophrenia is a serious mental illness that changes how a person thinks, feels, and behaves. People with schizophrenia experience hallucinations, disordered thoughts, and delusions. Latuda is approved to treat adults and adolescents ages 13-17 years of age with schizophrenia. It is not approved for use in older adults with dementia-related psychosis due to an increased risk of death.

What are the side effects of Latuda?

The most serious side effects of Latuda include:

  • Tardive dyskinesia (uncontrollable slow or jerky movements)
  • Low white blood cell count
  • Increased prolactin levels causing missed periods in females
  • Neuroleptic malignant syndrome
  • Changes in your metabolism can lead to high blood sugar levels, high levels of cholesterol or triglycerides, and weight gain

The most common side effects of Latuda include:

  • Muscle stiffness
  • Drowsiness

Drug interactions and  supplements

Latuda can interact with different types of drugs. These drugs include:

  • Antifungal medications such as fluconazole
  • Antibiotics such as erythromycin (to treat bacterial infections)
  • Heart medications such as diltiazem (Cardizem) and verapamil (Isoptin) for the treatment of high blood pressure
  • Mood stabilizers like carbamazepine (Tegretol) and lithium
  • Grapefruit and grapefruit juice can increase Latuda concentrations in your body
  • St John’s wort can reduce the amount of Latuda in your body.

This is not a complete list of drug interactions for Latuda. Consult your healthcare provider for medical advice and tell them about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Is Latuda safe in pregnancy and breastfeeding

It’s not known if Latuda can pass into breast milk. If you’re breastfeeding or planning to breastfeed, or are pregnant or planning to become pregnant speak with your doctor about the risks and benefits of using Latuda.

What can happen if I drink alcohol with Latuda?

Alcohol and Latuda have many common side effects because they are both central nervous system depressants. Alcohol can cause a worsening of symptoms and side effects of bipolar disorder or schizophrenia. You are at increased risk of some of the following side effects when you combine the two:

  • Low blood pressure
  • Reduced heart rate
  • Reduced rate of breathing
  • Fall in body temperature
  • Fainting or sedation
  • More likely to fall
  • Seizures

The clinical studies of Latuda do not include people with a history of alcohol abuse which means no data showing the specific interaction between Latuda and alcohol use exists. According to Lupin Pharmaceuticals the manufacturers of Latuda, people should avoid drinking alcohol as it may worsen the side effects of Latuda. If you take atypical antipsychotics, talk with your healthcare provider before drinking any alcohol.

How to transfer a prescription to another pharmacy

One of the common tasks that occur in a pharmacy is the transfer of a prescription. It sometimes seems like a time-consuming process for you as a customer but in fact, it is straightforward.

This is a quick guide to prescription transfer and some of the common questions you might have along the way.

What does it mean to transfer a prescription?

When you want to transfer a prescription you are basically wanting to change your current pharmacy to a new pharmacy. Transferring prescriptions over to a new pharmacy is common and easy to do. It is an everyday occurrence in a pharmacy.

There are several reasons why you might decide to switch pharmacies. Maybe the new pharmacy is a local pharmacy within walking distance, has better prescription prices and service, offers more pharmacy services eg. focus on wellness, or has a mobile app that allows communication with them at your fingertips.

What is a prescription?

A prescription is an instruction order from your doctor to the pharmacist. It states the name of the medication, the required dosage, and strength, the duration, the number of refills as well as the directions for taking or applying it. Drugs that are classed as prescription only require a prescription. On the other hand, over-the-counter drugs can be purchased directly from a pharmacy.

How do I transfer my prescription to a new pharmacy?

This process is simple and effortless provided that you have all your prescription information and personal details. They must be accurate and up to date. If you are unsure your new pharmacy is there to help.

Essential information your new pharmacy will need:

  • Your name
  • Date of birth
  • Phone number
  • Prescription number (Rx number)
  • Name of the medications you would like to transfer
  • Your medical history
  • Insurance information
  • The pharmacy where you are filling the prescription currently and their phone number

The information above will allow a smooth prescription transfer with minimal time delays.

It is recommended when transferring to a new pharmacy that you transfer every prescription you have. This will allow the pharmacist in charge to see a full picture of your medication usage, spot potential adverse reactions between medications and take into account any over-the-counter medication you may be taking.

Before transferring pharmacy you must be certain the new pharmacy will offer your prescription. Specific medications can not transfer to a different pharmacy including Adderall, Concerta, Vyvanse, Oxycontin, Percocet, Vicodin, and certain Schedule II controlled substances. Additionally, other medications can only be transferred once, even if you have more than one refill left e.g. Ambien, testosterone, Ultram, and Xanax. After transferring them once, you’ll need a new prescription from your doctor to switch pharmacies again.

Your new pharmacy will generally take responsibility for making sure your prescriptions are transferred from the old pharmacy. The pharmacist can also contact your doctor to sort out refills. Some insurance plans have preferred pharmacies but your new pharmacy will know if this is the case.

Does a prescription transfer take long?

A transfer request can take a few hours or up to 24 hours. If it is urgent ringing the old pharmacy directly and requesting a faster process for whatever reason is the best solution.

Your new pharmacy will then contact you once the prescription has been transferred to them. They will then dispense your medication on your next prescription refill date advised by your doctor.

The Cost of a Cold

The US states where a common cold costs the least

The common cold is just that – common. The average adult suffers from two to three colds every year, dealing with symptoms such as a runny nose, coughing, and headaches. While it may be a common occurrence, many of us probably haven’t given much thought to how expensive it can be if you’re hoping to alleviate the symptoms.

Viruses that cause colds don’t respond to prescription medications like antibiotics, so many of us turn to things such as cold and flu tablets and cough syrups to manage the symptoms while our immune systems do the hard work. But the cost of these remedies can add up and can prove to be more costly in some states than others.

We looked at the cost of a number of products that can help to alleviate symptoms including Tylenol Cold+Flu Severe Day/Night Caplets, Vicks VapoRub Cough Suppressant Ointment, and Robitussin Cough + Chest Congestion DM MAX Relief Liquid, as well as the cost of a doctor’s visit.

The states where a cold costs you the least

Lowest cost state for colds

Looking at the cost of the three products as well as the average cost of a visit to a family practice for someone with insurance, we can see which states have the lowest prices for those suffering from a cold.

1. Arkansas – $49.57 total cost

The southern state of Arkansas tops the list as the cheapest state for the common cold. The product costs are low, but the factor that sits this state at the top of the table is the low cost of a doctor’s visit at $23.90 for an average visit to a family practice with insurance.

2. Mississippi – $49.71 total cost

Arkansas’s neighboring state of Mississippi has the same product costs and an average doctor’s visit cost of just 14 cents more than in Arkansas, making it a particularly close second.

3. South Carolina – $49.86 total cost

The state of South Carolina has some of the lowest product costs so those suffering from cold symptoms can treat them cheaply, placing the state in third place.

The states where a cold costs you the most

1. Massachusetts – $59.93 total cost

With high product costs and a relatively high cost for a doctor’s visit, Massachusetts tops the list as the most expensive state for a cold. As the home of Harvard University and political dynasties such as the Kennedy family, the state is known to be affluent with a high cost of living.

2. Colorado – $57.35 total cost

The Centennial State comes in as the second most expensive state for a cold with Coloradans paying nearly $8 more for a cold on average than Arkansans. While the cost of a cold is high in Colorado, so is household income as one of the wealthiest states.

3. Hawaii – $56.22 total cost

The state of Hawaii may be something of a paradise, but you can expect the price tag that goes along with that, with the island being the third most expensive state for a cold.

 

The average cost of a cold

When we look at the prices overall, we can see the average costs for each element. So what does the average cold look like in terms of price?

It is thought that the average adult gets two to three colds per year, so if we take an average of 2.5 colds per year, that would cost each individual $128.85 every year.

Average cost of a cold

The best states for paid sick days

Cost isn’t the only important thing when considering which states are the best to live in when you have a cold. We also looked at the number of paid sick days employees get on average in each state to discover which states offer the best support.

 

The following states all offer an average of 12.4 paid sick days per year to workers, making these the best states for paid sick leave:

  • Missouri
  • Nebraska
  • Iowa
  • Kansas
  • North Dakota
  • Minnesota

The worst states for paid sick days

At the other end of the scale, these states offer just 7.8 paid sick days on average to workers, making them the worst states for anyone dealing with a cold or any other illness that requires time off.

 

Best and worst states for paid sick days ranked

 

If you’re struggling to pay for your medication, we may be able to assist. NiceRx provides access to FDA-approved medications, including Entresto, Trulicity, Emgality, Dupixent, Trintellix and Vraylar.

Methodology:

 Looking at the US states, we delved into the cost of having a cold by combining the cost of popular cold relieving products with the average cost of a doctor’s visit.

The cost of products was taken from Target’s website, choosing a store in the capital city of each state, making sure to avoid stores on college campuses where prices are often marked up. We took the cost for the three products listed below:

  • Tylenol Cold+Flu Severe Day/Night Caplets – Acetaminophen – 24ct
  • Vicks VapoRub Cough Suppressant Ointment
  • Robitussin Cough + Chest Congestion DM MAX Relief Liquid – Dextromethorphan – Honey – 8 fl oz

The cost of the average visit to a family practice with insurance came from Stacker.

The average number of paid sick days came from Farah and Farah.

Alaska and South Dakota were omitted from the research due to a lack of data for these states.

Viibryd and alcohol: can they be used together?

Viibryd is an FDA-approved antidepressant medication. It contains the active ingredient vilazodone which is classed as a selective serotonin reuptake inhibitor (SSRI). It is used to treat major depressive disorder (MDD), a mental health condition. Depression is also a part of bipolar illness. People with bipolar disorder who take antidepressants may be at risk of alternating from symptoms of depression to mania. Symptoms of mania include an irritable mood, overconfidence, decreased need for sleep, racing thoughts, and risk-taking behavior.

If you have MDD, you may notice that it impacts your quality of life, including your relationships, social habits, sleep, and appetite. If you add alcohol into your life the potential for problems increases greatly. Mixing Viibryd and alcohol is strongly discouraged by healthcare professionals. Read on to find out more about this.

What are the different types of antidepressants?

There are various classes of antidepressant medication. Below are the main ones:

Selective Serotonin Reuptake Inhibitors (SSRIs)

Viibryd belongs to this category. It is thought to work by correcting the imbalance of serotonin, a neurotransmitter in your brain. Low levels of serotonin may be linked to symptoms of depression. Some other commonly prescribed SSRIs are Paxil (paroxetine), Prozac (fluoxetine) Lexapro (escitalopram), Zoloft (sertraline), and Celexa (citalopram).

Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)

These work similarly to SSRIs. This type of antidepressant stops the brain from removing both the serotonin and norepinephrine that are released naturally. Norepinephrine helps enhance awareness and focus, as well as allowing the brain to create and recall memories. SNRIs create a build-up of norepinephrine to help combat the fuzzy, distant feelings often associated with depression. Common SNRIs include, Cymbalta (duloxetine), Effexor (venlafaxine) and Pristiq (desvenlafaxine).

Monoamine oxidase inhibitors (MAOIs)

Certain alcoholic beverages contain a substance called tyramine that can cause serious side effects if consumed while taking MAOIs. Side effects include a sudden, dangerous increase in blood pressure. Doctors will advise you against alcohol use if you are taking an MAOI. Tyramine is also found in certain foods, so your healthcare provider will give you advice on which foods to avoid. Excessive tyramine in the body can also cause dangerously high blood pressure. Marplan (isocarboxazid), Nardil (phenelzine), and Emsam (selegiline) are commonly prescribed MAOIs.

Viibryd is contraindicated in patients taking MAOIs, or those within 14 days of stopping MAOIs. This includes MAOIs such as linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome.

Tricyclic antidepressants (TCA)

TCAs show their greatest side effects during the first few weeks of treatment. At this point, it is not a good idea to consume alcohol. A few weeks after side effects have passed it’s generally considered safe to drink small amounts of alcohol. Elavil (amitriptyline), Silenor (doxepin), and Pamelor (nortriptyline) are commonly prescribed TCAs.

Norepinephrine and dopamine reuptake inhibitors (NDRIs)

Drugs in this category include Wellbutrin SR and XL (bupropion).

What Are The Possible Side Effects Of Viibryd?

Common side effects of Viibryd include:

  • Diarrhea
  • Nausea
  • Dry mouth
  • Drowsiness
  • Trouble sleeping

Serious side effects include:

  • Glaucoma – symptoms of angle-closure glaucoma may include eye pain, changes in vision, swelling, or redness in or around the eye
  • Serotonin syndrome symptoms such as palpitations, or irregular heartbeats when taken with sumatriptan, rizatriptan, tramadol, St. John’s wort, triptans, buspirone, and MAOIs
  • Viibryd may increase the risk of bleeding events. The combined use of aspirin, non-steroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, or naproxen), warfarin, and other anti-coagulants may increase this risk. This may include gums that bleed more easily, nose bleeds, or gastrointestinal bleeding. Some cases have been life-threatening
  • Viibryd and other antidepressants may increase suicidal thoughts or actions in young adults, especially within the first few months of treatment, or when the dose is changed. Viibryd is not recommended for use in children

To minimize drug interactions and the worsening of possible side effects you must inform your health care professional about any other medical conditions you have. Tell them about any other prescription drugs, over-the-counter medications, or supplements you may be taking. If you are breastfeeding and taking Viibryd, talk with your doctor about the potential risks and benefits.

This article is not medical advice. You should always speak with your doctor about your health conditions before commencing any treatment as they can provide you with specific drug information for Viibryd.

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Can you mix Viibryd and alcohol?

Taking Viibryd with alcohol is strongly discouraged by healthcare professionals. Viibryd can worsen the effects of alcohol, while alcohol can worsen antidepressant side effects. When you have depression, you have an increased risk of developing a substance use disorder. Mixing Viibryd with alcohol can lead to alcohol abuse, causing you to have the potential to become alcohol dependent. If you drink and develop an addiction to alcohol, it will become more difficult for you to control your symptoms of depression and to get your alcohol consumption under control.

The combination of alcohol and antidepressants can be very challenging if someone is drinking, binge drinking, heavy drinking, or has an alcohol use disorder prior to taking the antidepressants. Furthermore, if someone decides to stop taking drugs for depression and starts drinking alcohol for symptom management instead, they can worsen their symptoms of depression, in some cases leading to suicidal thoughts.

Getting help

Antidepressants are a useful option for depression but there are other ways to help you cope with your mental health condition. Your healthcare provider can discuss other treatment options and provide you with health information about mental illness. If you are concerned about yourself or a loved one’s alcohol use, joining a support group or a program such as Alcoholics Anonymous may help. The National Alliance on Mental Illness is also a useful resource that provides support and information to individuals with mental illness.

Charitable Nations

The most philanthropic places in the US and worldwide

The effects of the pandemic turned the world’s attention towards giving back and helping others. More Americans joined volunteering programs than ever before, and donations to health charities soared.

In the climate of giving, which are the most generous countries, states, and celebrities?

To find out, NiceRx analyzed each US state and OECD country to find the most charitable states and nations. We also investigated the American health charities receiving the most donations and the world’s most philanthropic celebrities.

The most charitable states in the US

Most charitable nations in US

1. Oregon | Charitable Score: 7.68/10

Oregon is the most charitable state in the US overall and has a giving score of 66, which is based on public volunteering and charitable donations.

The residents of Oregon also made more Google searches for charities, volunteering, and donating than any other state! There were 46,000 searches in the last twelve months for every 100,000 people living in the state.

There are also 168 public charities operating in the state of Oregon for every 100,000 people.

2. Minnesota | Charitable Score: 7.06/10

Minnesota comes in second place for charity and giving, scoring 7.06/10 overall. Minnesota’s giving score is 68, based on volunteering and donations – the highest giving score out of the top three states!

People in Minnesota made 34,000 Google searches per 100,000, in the past twelve months for charity-related search terms.

In Minnesota, there are 167 charities per 100,000 people, ranging in causes from health charities to environmental organizations.

3. Vermont | Charitable Score: 6.46/10

Vermont ranks as one of America’s most charitable states with an overall score of 6.46. With a giving score of 55, Vermont ranks lower than most states in this category.

There were around 20,000 Google searches made for every 100,000 people in Vermont for charity-related searches.

Vermont has the most charities out of all US states. There are 306 active charities for every 100,000 people in the New England state.

1. Mississippi | Charitable Score: 2.02/10

Mississippi is America’s least charitable state, with an overall score of 2.02 out of 10. WalletHub gave Mississippi a giving score of 46. The only states with a lower score are New Mexico and Arizona.

Residents of Mississippi made 10,000 charity-related Google searches in the last twelve months for every 100,000 of the state’s population.

There are 87 active charities working in Mississippi for every 100,000 people.

2. Louisiana | Charitable Score: 2.67/10

Louisiana ranks as one of the nation’s least charitable states, scoring 2.67 out of 10. Louisiana’s giving score is 48, accounting for public volunteering, charities, and donations.

There were 13,000 Google searches for every 100,000 people in Louisiana over the last twelve months.

In the state of Louisiana, there are 101 active charities per 100,000 people.

3. New Mexico | Charitable Score: 2.8/10

New Mexico has the lowest giving score out of all US states according to research from WalletHub, which gave the state a score of 44.

There were 16,000 Google searches made in the past twelve months for charities and volunteering, for every 100,000 residents of New Mexico.

The state has 132 active operating charities for every 100,000 people.

 

The most charitable nations in the world

1. New Zealand | Charitable Score: 7.18/10

New Zealand is officially the world’s most charitable country, scoring 7.18 out of 10.

New Zealand’s giving index score is 47 – higher than most countries on the list. The giving score is based on helping strangers, volunteering time, and monetary donations.

In New Zealand, there were 54,000 charity-related Google searches for every 100,000 people in the last twelve months.

There are 0.69 4-star US-based charities in New Zealand, for every 100,000 of the population.

2. United Kingdom | Charitable Score:  6.99/10

The UK ranks in second place as one of the world’s most charitable nations.

Charities Aid Foundation determined the UK to have a giving score of 41, according to volunteer time, helpful acts, and monetary donations.

There were more charity-related Google searches in the UK than in any other country. In the past 12 months, United Kingdom residents made 64,000 Google searches for charity-related words and phrases.

In the UK, there are 0.1 4-star US-based charities for every 100,000 people.

3. Canada | Charitable Score:  6.17/10

Canada is one of the most giving countries in the world, scoring 6.17 out of 10 overall.

Canada’s giving index score from Charities Aid Foundation is 38, higher than most countries on the list.

Canadian residents made 53,000 Google searches for charities and volunteering for every 100,000 people in the last twelve months.

Canada has 0.3 US-based 4-star charities for every 100,000 of the population.

 

The least charitable nations in the world


1. Japan | Charitable Score:  1.13/10
Japan ranks as the least charitable nation in the world, with a score of just 1.13.

Japan has the lowest giving index score, at just twelve. Although, Charities Aid Foundation highlights this could be due to complex rules around charity donations in Japan, and high expectations of state provision.

There were 3,000 charity-related Google searches for every 100,000 people made from Japan in the last year.

There are 0.08 4-star US-based charities that work internationally in Japan for every 100,000 of the population.

2. South Korea | Charitable Score:  1.85/10

South Korea scores 1.85 out of 10 overall as one of the least charitable nations. South Korea’s giving index score is 22 – equal to Italy.

There were fewer Google searches for charities and volunteering in South Korea than in most other countries.

A total of around 1,000 searches for every 100,000 people were made in the last year and the only countries with fewer searches are Colombia and Turkey,

There are 0.08 4-star US-based charities working in South Korea for every 100,000 people in the country.

3. Italy | Charitable Score:  1.94/10

Italy is one of the lowest-scoring countries and least charitable countries in the world. Italy’s giving index score from Charities Aid Foundation is 22 – lower than most countries on the list.

For every 100,000 of Italy’s population, there were 3,000 charity-related Google searches in the last year

There are 0.07 4-star US-based charities that work internationally in Italy for every 100,000 people.

 

The most charitable celebrities

Investigating the donations and volunteering time of the public gives insight into which are the most generous states and countries. However, the income of ordinary people is sometimes just a fraction of the earnings of some celebrities.

Below are the most charitable celebs in the world, based on the number of charities each has supported, the number of causes supported, and the number of news articles written about celebrity charity efforts.

1. Sting | Country: United Kingdom | Score: 8.5/10

Sting, the British musician and former member of the Police, tops our list as the most philanthropic public figure in the world.

Sting has supported 158 charities, based in countries all over the world. The 46 causes Sting has supported include Parkinson’s Disease, anti-bullying and LGBT support.

There are 246 total news articles online about Sting’s charity efforts.

2. Elton John | Country: United Kingdom  | Charitable Score:  6.35/10

Often commended for donating hundreds of millions of dollars to charity organizations, Elton John ranks as one of the most charitable celebrities in the world.

The British musician has supported 64 charities and foundations and founded the Elton John AIDS Foundation.

Elton John has supported 33 charitable causes, including homelessness and cancer.

There are 445 articles online regarding Elton John’s charitable efforts – more than any other celebrity!

3. Annie Lennox | Country: United Kingdom  | Charitable Score:  5.64/10

British singer and member of Eurythmics, Annie Lennox is one of the world’s most giving celebrities.

Lennox has supported 86 charities in total, across 32 charitable causes. Lennox has given to organizations supporting environmental conservation, poverty, and human trafficking.

There are a total of 305 online news articles about Annie Lennox’s charity efforts.

The health charities getting the most donations

The COVID-19 pandemic put added pressure on many people’s physical and mental health. From limited access to healthcare to a lack of affordable medication, there has been an increasing demand for support from charities and organizations.

Below are the health charities that had the highest amount of donations in the latest fiscal year.

1. American Cancer Society |  Donations: $710M | Charitable commitment: 79%

The American Cancer Society received the most private donations out of all health charities in the States. The charity made $710 million in donations in a single year.

79% of all expenses from the American Cancer Society went directly towards its purpose of medical research and supporting cancer patients.

The Better Business Bureau Wise Giving Alliance’s recommended minimum for charitable commitment is 65%.

2. American Heart Association | Donations: $610M | Charitable commitment: 79%

The American Heart Association received an astonishing amount of private donations, totaling $610 million in a single fiscal year.

The American Heart Association dedicated 79% of its spending on directly supporting the charity’s purpose.

3. Patient Access Network Foundation | Donations: $434M | Charitable commitment: 97%

The Patient Access Network Foundation helps patients get the medication they need access to, despite a lack of insurance.

The charity received $434 million in donations in just one fiscal year, making it one of the most highly funded health charities in America.

97% of the network’s total expenses went directly towards supporting the cause, instead of management, marketing, and fundraising efforts.

 

Free Clinics: Helping those medically underinsured

Although some health charities provide support to the 41 million Americans who are medically uninsured or underinsured, free clinics are an essential part of the safety net.

The first free clinic opened in 1967, and clinics today are dedicated to offering medical services for disadvantaged people. They perform medical checks and procedures at a lower cost subsidized by the government and private donors, or for free.

Although free clinics bridge the gap between the economically disadvantaged and citizens with health insurance, the organizations operate on a local level and struggle to treat all patients that would benefit from their services. Most medical staff at free clinics are volunteers from the local medical community. The American Journal of Medical Studies recorded there are on average 156.7 volunteer staff and 6.9 paid employees per clinic – a statistic that is especially worrying in the current circumstances of Covid-19 which has left many less fortunate Americans struggling to access treatment.

The National Association of Free and Charitable Clinics, which oversees participating member free clinics in the country, reported that free clinics have requested over $16 million worth of funding since the start of the pandemic. Private companies have donated $4.25 million to date, showing the need for greater support.

Eliquis and alcohol: can they be used together?

Have you just picked up your Eliquis medication from the drug store? You may have noticed the alcohol warning labels. Alcohol and medicines don’t generally go together. Ideally, they should be like two sides of a coin never interacting! Here’s why taking Eliquis with alcohol isn’t a good idea. But let’s first start off by understanding what Eliquis is.

What is Eliquis?

Eliquis is a fairly new anticoagulant medication that was approved for use in 2012. In comparison warfarin (Coumadin) is the most widely used blood thinner that has been around since 1954. Eliquis works by blocking an important process in the body called blood clotting. It involves many complex steps that lead to coagulation (the process of blood thickening). The role of Eliquis is to eliminate blood clots and interfere in the blood clotting process in certain types of patients.

What is blood clotting?

When you get hurt, blood cells called platelets gather at the injury site and form a blood clot. These cells are sticky, and they form clumps creating a plug. Clotting factors are also released from platelets that help form a mesh to form the plug to close the wound.

The clotting process is essential when you’re injured. Sometimes, however, a blood clot can appear in blood vessels such as the aorta artery that supplies your heart or brain with oxygen-rich blood. When a clot blocks blood flow to your heart, it can cause a heart attack. If it blocks the blood flow to your brain, it can cause a stroke. Blood thinners like Eliquis are used to prevent strokes and potentially fatal blood clots.

The use of blood thinners such as Eliquis in groups of patients who have a higher risk of bleeding due to heart disease or heart conditions, risk of stroke, and high blood pressure is common.

How does Eliquis work?

Eliquis contains the active ingredient apixaban, an anticoagulant medicine that prevents blood clots from forming. Eliquis is classed as a Factor Xa inhibitor. It blocks the clotting factor called factor Xa which prevents clots from forming i.e. decreases blood clot production. Clots can be stopped from forming and getting larger, however, apixaban can not break up clots that are already there.

Other medications in this category include Xarelto (rivaroxaban), Savaysa (edoxaban), and Arixtra (fondaparinux).

Eliquis has several indications. Eliquis can be used to:

  • Reduce the risk of stroke and embolism in patients with atrial fibrillation
  • Prevent deep vein thrombosis (DVT)
  • Treat DVT
  • Treat pulmonary embolism
  • Reduce the risk of a recurrence of deep vein thrombosis and pulmonary embolism

Occasionally your healthcare provider will want to check the health of your kidneys when taking Eliquis, with a blood test. You do not need to have routine blood testing to check the amount of apixaban in your body.

Side effects with Eliquis

Bleeding is the most common and serious side effect of Eliquis. If you take Eliquis you have an increased risk of:

  • Bleeding gums when you brush your teeth
  • Nosebleeds
  • Bruising easily
  • Small cuts bleeding more than usual
  • Longer or heavier menstrual bleeding (women)

Is it safe to drink alcohol while taking Eliquis?

It is best to avoid alcohol while taking Eliquis. This is because it can increase the risk of bleeding in your stomach and intestines. If you do drink alcohol, the recommended alcohol consumption is no more than 1 drink a day for a woman, and no more than 2 drinks at a time for a man.

The risks of combining alcohol and blood thinners are even more dangerous if you also take another medication that also interacts with blood thinners. Drug interactions with the following medications are possible:

  • Antibiotics e.g. Biaxin
  • Antifungals e.g. Nizoral
  • Antidepressants e.g. Prozac
  • Anticonvulsants e.g. Equetro
  • Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen
  • Foods rich in vitamin K e.g. dark, leafy green vegetables
  • Cranberry juice

Does Eliquis affect how other medicines work?

You may have a higher risk of bleeding if you take Eliquis while you are taking other medicines that also lower your body’s ability to form clots. These include:

• Aspirin or products that contain aspirin

Other drugs may also affect how apixaban works in your body. It is very important to tell your doctor or anticoagulation clinic whenever you start or stop any medicine. This includes medicines you can buy without a prescription, herbal products, and vitamins.

Are there resources available to help me reduce my alcohol intake?

If you think excessive drinking such as binge drinking and heavy drinking is something you need help with The Substance Abuse and Mental Health Services Administration (SAMHSA) can be contacted.

Binge drinking is described as consuming 5 or more drinks (male), or 4 or more drinks (female), in about 2 hours and is the most common form of excessive drinking. Heavy drinking is defined as consuming more than 4 drinks on any day (male) or more than 3 drinks on any day (female)

If your alcohol intake looks excessive, seeking medical advice from a healthcare professional is recommended. They can help you access the correct medical attention for your alcohol use.

Humira and alcohol: can they be used together?

Alcohol and prescription drugs can interact harmfully even if they are not taken at the same time. You may be wondering if it is safe to take Humira and drink alcohol. There is no solid scientific evidence against this, but health professionals strongly advise not to consume alcohol when using Humira due to the risk of liver damage. To learn more about how Humira works and the dangers of combining it with alcohol read on.

What is Humira?

Humira (adalimumab) is an injectable prescription drug manufactured by AbbVie and is FDA-approved. It is used to treat autoimmune conditions like rheumatoid arthritis, Crohn’s disease, and psoriasis. The medication is a class of biologic medications known as tumor necrosis factor (TNF) blockers.

What is a TNF blocker?

TNF is a protein in the body that can cause inflammation. Normally excess TNF in the blood is naturally controlled. But, in people with certain immune conditions, TNF levels are higher leading to excessive inflammation. Inflammation is harmful to your body when it is out of control e.g. severe pain and swelling.

Humira causes a reaction in your immune system by binding to TNF and preventing it from triggering the inflammatory reaction. Other TNF blockers that are FDA approved include:

What is Humira used for?

Humira can be used used to treat:

  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Crohn’s disease
  • Ulcerative colitis
  • Plaque psoriasis
  • Polyarticular juvenile idiopathic arthritis
  • Psoriatic arthritis
  • Hidradenitis suppurativa
  • Uveitis

Side effects of Humira

Humira is an effective treatment but like all prescription medications, it can cause side effects. Side effects should always be discussed with healthcare professionals.

People may experience the following common side effects after taking Humira:

  • Injection site reactions e.g. bruising, or itching
  • Joint pain
  • Weight loss
  • Shortness of breath
  • Coughing
  • Diarrhea
  • Fatigue
  • Stomach upset

Examples of the most serious and less common side effects relating to taking Humira include:

  • Liver damage/liver problems – yellowing of the eyes or skin, right-sided abdominal pain, vomiting, and fatigue
  • Nervous system problems – numbness and tingling in hands and feet, vision changes, and dizziness
  • Allergic reactions – ranging from difficulty breathing to swelling of the eyes, lips, and face
  • Immune system changes – lupus-like reaction to including symptoms such as joint pain, rash on cheeks or arms, chest discomfort, or shortness of breath
  • Increased risks for infections – these include tuberculosis and other opportunistic infections due to viral, bacterial, or fungal illnesses

Live vaccines such as yellow fever, BCG, cholera, typhoid, varicella should never be given to Humira patients. There is also an increase in the risk of serious infections when Humira is taken with abatacept (Orencia) and anakinra (Kineret)

Can you drink alcohol with Humira?

Risk of liver damage

The main concern about alcohol and Humira use is damage to the liver. However, there is currently limited research on the safety of Humira and alcohol when taken together. This does not mean the combination is safe.

TNF inhibitor use alone can increase liver enzymes. When alcohol is added Humira may not work as effectively, or the drug is released into the system in higher doses. Either way, this may lead to complications and risk of severe liver injury.

Alcohol alone can also damage the liver. Because the liver breaks down alcohol, doctors believe it is possible that drinking alcohol could increase the risk of liver damage. However, scientists need to do more research.

While there is a lot of conflicting information, what researchers know for sure is that alcohol, autoimmune diseases, and TNF inhibitors can damage the liver on their own and when taken in combination. In addition, other medications used to treat and manage pain associated with autoimmune conditions cause organ damage.

Additionally, many patients who take Humira are also using methotrexate to treat their condition, particularly with rheumatoid arthritis. Most healthcare professionals recommend that people taking methotrexate limit or avoid alcohol consumption even in the absence of liver disease.

Commonly prescribed medications used with Humira

Humira is commonly used with a class of medications known as disease-modifying antirheumatic drugs (DMARDs).

Examples of DMARDs include:

Depending on the condition it’s being used to treat, Humira may or may not be used with other drugs.

Many patients who use Humira also use

  • Methotrexate to help control rheumatoid arthritis symptoms
  • Topical corticosteroids for the treatment of plaque psoriasis
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) for treatment of hidradenitis suppurativa

Possible alcohol drug interactions can occur with other medicines such as methotrexate, NSAIDs, and corticosteroids like prednisone (Deltasone). For example, methotrexate is broken down in the liver. In general, long-term use of methotrexate can also lead to liver toxicity. Most health care providers recommend that patients avoid or limit alcohol consumption when using methotrexate.

Final word

Overindulging in alcohol frequently puts you at risk for chronic liver damage and other health-related risks. When Humira is combined with excessive alcohol consumption, the risk for permanent organ damage is potentially increased. You should openly discuss your drinking habits and the importance of social life by balancing your condition with your healthcare provider. They can help you understand the risks of drinking alcohol based on your specific health history. This content is not intended to be a substitute for professional medical advice.

Vyvanse and alcohol: can they be used together?

So, you are wondering if it’s safe to take Vyvanse with alcohol? Drinking alcohol with prescription drugs is a common question. You are not alone in asking this. The truth is it’s problematic and it’s never a good idea to mix the two. Read on to find out what you need to know about the health risks of alcohol with Vyvanse.

What is Vyvanse?

Vyvanse is the brand name of lisdexamfetamine belonging to a class of drugs known as Central Nervous System stimulants (CNS stimulants). It is used to treat symptoms of Attention Deficit Hyperactivity Disorder (ADHD). It is also used to treat moderate to severe binge eating disorder (BED). Vyvanse is a prescription stimulant medication but is also classed as a Schedule II controlled substance. This puts Vyvanse into a category of drugs in which there is a high abuse risk leading to severe psychological and physical dependence.

The FDA warns of the risk of substance abuse with amphetamines. They also highlight that heart problem and psychosis is more likely to occur when these stimulant medications are taken for the treatment of ADHD.

The active ingredient in Vyvanse is called lisdexamfetamine dimesylate. It helps with brain activity by increasing the amount of norepinephrine and dopamine in your brain. These two substances are naturally produced in your brain and they help to send signals between your neurons.

What Substances are Considered Amphetamines?

Examples of prescription amphetamines include:

  • Methylphenidate (Concerta)
  • Methylphenidate (Ritalin, Ritalin SR)
  • Amphetamine and Dextroamphetamine (Adderall)

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Side effects of combining alcohol with Vyvanse

Drinking alcohol and taking stimulant medications such as Vyvanse often result in each substance working directly against one another. For instance, alcohol minimizes some of the stimulant effects of Vyvanse, and Vyvanse reduces some of the sedating effects of alcohol. An individual may continue to use more of one or both of the drugs to reach the desired effect, which may lead to a number of potentially dangerous results, including overdose.

Some of the common side effects of combining alcohol with Vyvanse

  • Sudden changes in blood pressure
  • Increased heart rate
  • Chest pains
  • Heart attack
  • Stroke
  • Risk of seizure
  • Hyperactivity
  • Feelings of euphoria

Dangers of Mixing Vyvanse and Alcohol

There are hidden dangers to the combination between alcohol use and Vyvanse. Combining the two substances has other long-term risks far beyond its short-term side effects, especially if you’re misusing prescribed Vyvanse or taking it without a medical reason.

Potential risks:

Alcohol Poisoning

Vyvanse stimulates the central nervous system (CNS). Alcohol is known to depress the central nervous system.

Mixing ADHD medication and alcohol means it takes a lot longer for your body to feel the symptoms of depression. To put it simply it will take you nearly twice as long to get drunk. That means you are consuming double the amount of alcohol you would normally drink, which could lead to alcohol poisoning or alcohol-related injuries. How can this happen?

Vyvanse has a more powerful stimulant effect than the sedative effects of alcohol. It can mask the feeling of being drunk when taken with alcohol, so you continue to drink more as the brain has no signal to stop you from drinking. Alcohol can also intensify many of the psychological side effects of Vyvanse.

Heart Issues

High blood pressure is one of the most significant risks of mixing an amphetamine with alcohol. Taken alone, Vyvanse can increase your heart rate, but add in alcohol and the side effects become even greater.

If you suffer from poor health, the risks are especially high. You could have health complications if you have heart problems. Very fast heart rates could lead to potentially severe side effects, such as sudden stroke, heart attack, and even death.

Increase in Risk-Taking Behaviors

Since Vyvanse minimizes the normal signs of drunkness some individuals may take part in more reckless behaviors such as:

  • Drink driving
  • Getting into a road traffic accident
  • Getting into a physical altercation
  • Self-harm
  • Harming others

All these behaviors may occur if individuals mix their Vyvanse and alcohol without realizing that they’re impaired. They become a danger to themselves and others around them.

Increased Chances of Psychosis

Mixing Vyvanse and alcohol can cause or worsen the signs and symptoms of psychosis such as hallucinations and delusions, severely disrupting perception, thinking, emotion and behavior. Individuals who have a mental health condition such as bipolar disorder or schizophrenia are even more severely affected.

Potential for Addiction

The combination of a stimulant and a depressant can lead to polysubstance abuse. Polysubstance abuse is a combination of drug and alcohol addiction. Both alcohol and ADHD medications are potentially addictive substances. Especially for those who are suffering from ADHD, who are already at a higher risk for developing substance abuse problems. The combination of stimulants and alcohol puts you at a higher risk of mental health problems, poor physical health, and severe addiction. This risk is increased when prescription drugs and alcohol are mixed.

Polysubstance abuse often means a more complicated detox and rehab process for you. SAMHSA’s National Helpline is a free, confidential information service for individuals and families facing mental and/or substance use disorders.

Blood thinners and alcohol: can they be used together?

You have probably experienced some unpleasant side effects if you’ve mixed drinking with prescription medication. Some combinations are more dangerous than others. Have you recently started taking blood-thinning medication following a stroke? or are you someone who has taken blood thinners for many years? Are you unsure of the risks associated with combining blood thinners and alcohol? Here we look at what you need to be aware of if you’re taking blood thinners and alcohol together.

What are blood thinners and how do they work?

When you get hurt, blood cells called platelets gather at the injury site and form a blood clot. These cells are sticky, and they form clumps creating a plug. Clotting factors are also released from platelets that help form a mesh to form the plug to close the wound.

The clotting process is essential when you’re injured. Sometimes, however, a blood clot can appear in an artery that supplies your heart or brain with oxygen-rich blood. When a clot blocks blood flow to your heart, it can cause a heart attack. If it blocks the blood flow to your brain, it can cause a stroke. The use of blood thinners in this group of patients is common. Warfarin (Coumadin) is the most widely used blood thinner.

Doctors have the option of prescribing three types of blood-thinning medications which work at different stages of the blood clot formation process:

Antiplatelets

These drugs prevent blood platelets from sticking and forming clots.

Anticoagulants

These drugs work by blocking the clotting process in the blood.

Fibrinolytics

  • Activase (Alteplase)
  • Streptokinase (Streptase)
  • Urokinase

These drugs work by breaking fibrin formation causing the clot to dissolve.

Blood-thinning medications are used in patients who are at risk of developing blood clots that could block a blood vessel and disturb the flow of blood around the body. You will most likely be prescribed this medication if you have conditions such as:

  • Atrial fibrillation, also known as an irregular heartbeat
  • Recent knee or hip replacement and are at risk of deep vein thrombosis (DVT) and pulmonary embolism
  • Heart disease

Generally, these medical conditions can cause blood clots and anticoagulant medications increase your risk of bleeding. Patients taking blood thinners to treat heart disease often also take medications, such as PraluentRepathaWelcholColestid, and Livalo which help to reduce cholesterol levels. As a side effect statins can reduce the level of platelets in your blood, suggesting these drugs might also act as mild anticoagulants.

What else thins your blood and increases your risk of bleeding? Drinking alcohol. Combine alcohol use and anticoagulants and there is an increased risk of bleeding.

Why is it a risk?

One of the functions of your liver is to break down alcohol and some medications. If your liver is busy working hard removing the alcohol instead of your blood thinner, the level of the drug in your blood will go up and raise your bleeding risk.

When the body’s ability to clot is reduced internal vessels may begin bleeding inside the body. When enough liver damage has been endured there is a risk of bleeding and shock.

The amount of alcohol consumption has differing effects on the body depending on how much is consumed with blood-thinning medications:

  • Occasional drinking with blood thinners and alcohol does not put you at significant risk and does not appear to interfere with the job of anticoagulants
  • An excessive amount of alcohol (binge drinking) in combination may result in extreme blood thinning due to their synergistic effect
  • Regular drinking can result in the blood becoming too thin. The drug loses its effectiveness e.g. gums, minor cuts, and scratches may bleed much more than they usually would
  • Drinking alcohol in moderate amounts has been shown to thin the blood, but medical professionals do not recommend drinking as a substitution for a prescription blood thinner

Is this a short-term effect?

Alcohol intake is the main factor determining how long the effects last. In people who drink moderately, the effect of alcohol on platelets is short-lived.

According to The U.S. Dietary Guidelines for American adults, moderate drinking is classed as follows:

  • For women – up to one drink per day
  • For men – up to two drinks per day

Examples of one drink include:

  • 12-ounce beer at 5% alcohol
  • A 5-ounce glass of wine at 12% alcohol
  • 1.5 ounces of hard liquor at 40% alcohol

If you drink heavily, there can be a rebound effect in that the bleeding risk increases, even after you’ve stopped drinking. Exceeding the recommended guidelines above is considered heavy drinking.

Side effects of mixing alcohol and blood thinners

These are the side effects associated with combining alcohol and anticoagulants:

  • Nosebleeds
  • Bleeding of gums
  • Continued bleeding from cuts or injury
  • Heavier menstrual flow
  • Easy bruising
  • Blood in urine, vomit, or stool
  • Lower blood pressure
  • Dizziness, fainting
  • Nausea and vomiting
  • Breathlessness
  • Chest pain
  • Confusion

Can alcohol thin your blood?

Yes, alcohol can thin your blood. It interferes with the clotting process in two ways:

  1. It disrupts blood cell production in the bone marrow reducing the number of platelets in the blood.
  2. It makes the platelets you do have less sticky.

Females retain more alcohol in the bloodstream than males, so they are at higher risk of developing problems from combining alcohol with medications.

Combining alcohol and medications also carries an increased risk for older adults. The speed at which the body breaks down alcohol slows with age, meaning that alcohol remains in the bloodstream for longer.

Although alcohol reduces blood clotting, it should never be used as a replacement for anticoagulants.

Treatment for alcohol use disorder

Alcohol can have an impact on every system in the body causing health problems throughout the body: cardiovascular disease, liver disease, immune system problems, cancer, ulcers, and disturbance of the gastrointestinal system. Many of these problems can lead to life-threatening outcomes.

The treatment of alcohol dependency involves a variety of different methods. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute of Health (NIH) are both trusted sources you can access to get help for yourself or a loved one. A combination of medical advice from a health care provider, social, and family support is also essential.

10 prescription drugs you should not drink alcohol with

Did you know that alcohol is the third-leading preventable cause of death in the United States? Alcohol-related deaths are estimated at 95,000 deaths per year in the United States. Problem drinking can take many forms, one of which is mixing alcohol with prescription drugs. Is this something you are worried about? Mixing alcohol and prescription drugs is a real danger. You’ve probably seen the warning on medicines you’ve taken. Let us look at 10 prescription drugs in particular that you should not take with alcohol.

What are prescription drugs?

Prescription drugs are medicines that can be given by your doctor with a medical prescription. These drugs are safe and effective when used under a doctor’s supervision. When prescription drugs are misused, they can commonly become addictive and dangerous, particularly when combined with alcohol. Drugs such as opioid painkillers, antidepressants, and stimulants are some of the most frequently abused prescription medications.

In contrast, over-the-counter medications do not require a prescription. These medicines can however still cause problems when combined with alcohol too. Some medications such as painkillers and cough, cold, and allergy remedies contain ingredients that can react with alcohol. For example, Tylenol Cold and Flu (acetaminophen/dextromethorphan/guaifenesin/phenylephrine) or an antihistamine such as Zyrtec (cetirizine) taken short-term with alcohol can cause health problems. Cold and allergy medications are taken innocently for immediate relief of symptoms but can also interact dangerously with alcohol causing liver damage and other serious side effects.

What are the side effects of prescription drugs and alcohol?

Most medications cause minor side effects on their own, such as drowsiness, nausea, vomiting, loss of coordination, and changes in blood pressure. Long-term side effects of prescription drugs such as heart problems and liver damage also are possible and vary from drug to drug. If we decide to mix alcohol with prescription medications potentially far more harmful interactions can happen in three ways:

  • Change the performance of the drug
  • Stop the drug from working completely
  • Increase the impact of the side effects of the drug

Let us look at specific prescription drugs that are most likely to interact dangerously with alcohol making them harmful.

Opioids

Drugs in this category include oxycodone, codeine, hydrocodone, and morphine. These are pain medications that are addictive making them dangerous enough when taken on their own. Illicit drugs in this category are heroin and cocaine which lead to substance abuse on a much greater scale.

The combination of opioid painkillers and alcohol dramatically increases drowsiness, confusion, hallucinations, and overdose. Taken together, alcohol and prescription pain medications cause slow breathing and loss of motor control. A 2017 study published in the American Society of Anesthesiologists showed that drinking even a modest amount of alcohol with one oxycodone tablet caused significant breathing problems.

Another study has shown that taking long-acting/extended-release opioid painkillers with alcohol can cause rapid release and absorption of the drug into the body leading to a fatal risk of overdose.

Antidepressants

Antidepressant drugs include escitalopramcitalopramfluoxetine, and sertraline. They work by correcting chemical imbalances in the brain that affect changes in mood and behavior. Alongside medication, talking therapy such as cognitive behavioral therapy may be offered as a tool for individuals to understand their mental health condition.

When you drink alcohol with anti-depressants they work less effectively and symptoms of depression can intensify. Cognitive processes like memory or thinking can be distorted. You may feel very drowsy or sedated. Older classes of antidepressants, called monoamine oxidase inhibitors are sometimes used for patients. This type of antidepressant can damage the heart when mixed with alcohol causing high blood pressure, increased risk of blood clots, and heart attack. This can all lead to lasting harm or can even be life-threatening.

Stimulants

Ritalin, Adderall, and Concerta are stimulants that when combined with alcohol mask the effect of alcohol. This makes it extremely difficult to judge a person’s level of intoxication, which can lead to overdrinking. An individual will experience an increase in heart rate, arrhythmia, and high blood pressure leading to a possible heart attack or stroke.

Antipsychotics

People who take antipsychotics like Seroquel or Zyprexa suffer from conditions like schizophrenia, personality disorder, and some forms of bipolar disorder. These conditions can be managed so the individual can lead a happy life but people who struggle with schizophrenia and other related conditions will likely abuse all kinds of substances, especially alcohol, and marijuana. Mixing alcohol with antipsychotics makes the prescription medicine less effective, so hallucinations and delusions may return. Antipsychotics can lead to sedation, sleepiness, or excessive fatigue, and drinking too much can enhance these effects.

Cholesterol medications

Alcohol and cholesterol-lowering medications e.g. AtorvastatinSimvastatin, and Rosuvastatin can lead to liver damage and internal bleeding. Just having one drink per day while taking cholesterol medications may increase your risk of developing problems.

Benzodiazepines

Benzodiazepines are used mainly as an anti-anxiety medication to relieve symptoms such as restlessness and feelings of danger/panic or intense worry. Alcohol and benzodiazepines, such as Xanax and Valium, together cause a synergistic effect that can make you pass out and stop breathing. A synergistic effect gives rise to a greater, more powerful effect than if the two substances worked alone. Side effects of mixing alcohol with Xanax include drowsiness, dizziness, memory loss, loss of consciousness, and death.

Arthritis medications

Mixing arthritis medications with alcohol can increase your risk for stomach ulcers and bleeding in the stomach, as well as liver problems. Medications for this condition include CelecoxibNaproxen, and Diclofenac, and should not be taken with alcohol.

Muscle relaxers

Muscle relaxants are generally used to treat spasms in the back and neck to help reduce pain. Drugs in this category work in different ways, some work on the central nervous system, and others work on the muscle directly.

Serious side effects are seen when combining these medications with alcohol, including drowsiness, slow breathing, memory loss, reduced motor control, and seizures. Medications such as carisoprodol, cyclobenzaprine, and metaxalone should not be taken with alcohol.

Sleeping pills

Mixing alcohol and sleeping pills is another dangerous combination. These drugs work in a way that slows down activity in the brain to aid a person in falling asleep. Combined with alcohol, coordination is seriously affected. Memory problems and disruption to the central nervous system result in passing out. Drugs such as AmbienLunesta, and Sonata are used to aid sleep.

Blood thinners

Heparin, Coumadin, and Lovenox are blood-thinning medications known as anticoagulants designed to reduce your blood’s ability to clot. At the same time, this means you are more likely to bleed easily.

Drinking while taking a blood thinner puts people at increased risk of a stroke or a heart attack. Even occasional drinking while taking a prescription blood thinner, can cause internal bleeding. Heavy drinking can also cause internal bleeding, and increase the risk of blood clot formation.

Some people may use prescription medications and alcohol together to intensify the effects of both substances deliberately. These patients must get help from a treatment center that specializes in substance abuse. The National Institute on Drug Abuse states “prescription painkillers, sedatives, antidepressants, and antipsychotics are the most commonly used drugs mixed with alcohol. There are many treatment options available for addiction treatment including detox.

So many of the interactions between drugs and alcohol are dangerous, you must never mix alcohol with any drugs without first consulting a physician. The effects of alcohol with prescription drugs are unpredictable causing health problems for you and in turn, worrying for loved ones. Getting help is essential if you or someone you care about is struggling with alcohol and prescription drug abuse.

Complications of diabetes

It is most important to realize if diabetes is not treated correctly, it can seriously affect your body. The first thing to remember is you can treat many of the possible problems from diabetes. Unquestionably treatment is most effective when complications are picked up early. Therefore attending regular checkups is vital.

Two types of complications can occur. Firstly, short-term complications (also known as acute) that occur rapidly in the body e.g. hypoglycemia. Secondly, long-term complications (also known as chronic) that take time to develop due to uncontrolled diabetes. Extensive studies in the US (the Diabetes Control and Complications Trial) have shown that any improvement in blood glucose control will reduce your risk of developing complications. For that reason we want you to understand what these complications are and how to avoid them. Read our following guide to the most common complications of diabetes and how to prevent them.

What are the complications of diabetes?

Hypoglycemia

In simple terms, hypoglycemia is low blood sugar (blood glucose). You need to be particularly aware of the possibility of blood sugar levels dropping if you use insulin or take sulfonylureas, eat irregularly, exercise, and drink alcohol.

If your blood sugar levels drop too far, you will experience the following symptoms:

  • Sweating, or feeling cold and clammy
  • Dizziness
  • Blurred vision
  • Looking pale
  • Drowsiness
  • Confusion
  • Irritable, upset, or angry
  • Tingling lips
  • Lightheadedness
  • Fast heart rate
  • Hunger

You can treat the problem with a glass of orange juice, glucose tablets, or sugar cubes as soon as you notice these symptoms. It is always advisable to keep a glucagon injection with you for an emergency.

Diabetic ketoacidosis complications

Frequent and prolonged high blood sugar levels can lead to diabetic ketoacidosis. Your blood becomes acidic due to the presence of ketones. This is because your cells are starved for energy and your body begins to break down fat. Ketone bodies (byproducts of fat breakdown) then build up in your body. This causes a fruity smell on your breath and is one of the classic ways your doctor can make a diagnosis.

Early symptoms of ketoacidosis:

  • Thirst or a very dry mouth
  • Frequent urination
  • High blood glucose (blood sugar) levels
  • High levels of ketones in the urine

Then other symptoms appear:

  • Constantly feeling tired
  • Dry or flushed skin
  • Nausea, vomiting, or abdominal pain
  • Difficulty breathing
  • Unable to concentrate
  • Confusion

You can use a urine test strip to easily detect ketones. Many experts advise checking your urine for ketones when your blood glucose is more than 240 mg/dL. You need to treat diabetic ketoacidosis immediately as it is a medical emergency.

Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNS)

What is HHNS? Let us break down this condition for you.

Hyperosmolar Hyperglycemic Nonketotic Syndrome is a serious complication of diabetes where you can find yourself with the highest blood glucose levels. Hyper means ‘above normal’. Osmolar means ‘concentration’. Nonketotic means no ketones are created in the blood. HHNS does not make your blood as acidic as ketoacidosis.

You will experience symptoms of weakness, thirst, decreased mental awareness, frequent urination, and rapid pulse.

This condition is most likely to occur in the elderly if they live alone and those who are unwell. A person with HHNS will have high blood sugar levels where their body will pass excess sugar in the urine. These groups can lose large quantities of fluids through sickness and diarrhea and not replace them. When you do not rehydrate your body your blood glucose continues to rise. You become increasingly confused and less mentally aware. Eventually, you will reach a point that sends you into a coma. Just like ketoacidosis, this condition is also a medical emergency.

Diabetic kidney disease

People with diabetes tend to develop some degree of kidney damage. In the US diabetes is the leading cause of kidney failure in adults, making up half of all new cases.

The kidney’s primary function is to remove excess water and waste from the body through your urine. The small vessels that do this job form a delicate network that filters out unwanted substances. This network can be damaged by high blood sugar levels, causing substances such as protein to enter your urine. To put it another way, it is like making holes in a tea strainer allowing larger tea leaves to appear in the cup. Finding protein in your urine is an early sign of diabetic kidney damage.

The microalbuminuria test is a urine test for albumin that your doctor will carry out to detect these early signs. Albumin is a protein and if found in your urine by this test your doctors will keep an eye on you to prevent more serious kidney damage or even kidney failure from happening in the long term.

Blood vessel damage

In the body, damage to blood vessels can occur when glucose levels are high. For a diabetic, this means possible complications with your blood circulation, foot problems, and heart disease.

Diabetic neuropathy

Another system of your body that is affected by diabetes is your nervous system. Nerve disease or neuropathy is seen most often in people that have had diabetes the longest. There are various forms of diabetic neuropathy:

  • Disorders linked to sensory nerves – this is the most common for diabetics and is particularly foot-related. You are unable to feel the position of your foot, as well as not being able to feel tingling or burning. This can cause pain and infections of the feet to go unnoticed, causing potentially serious problems
  • Disorders due to loss of motor nerves – this prevents your muscles from moving e.g. if the muscles to your face are affected then you may not be able to smile
  • Disorders of automatic nerves – muscles that move without you even knowing can be affected e.g. your heart pumping blood around your body

Foot and skin problems

You need to be aware of changes to your feet and skin that arise because of your diabetes.

Neuropathy makes your feet less sensitive to pain and temperature. When the ability to feel your feet reduces you are less likely to notice problems that occur. In the early stages, people often complain of pins and needles. As this progresses you are less likely to notice accidental injuries or infections. Poor care may turn breaks in the skin or small sores into deeper skin ulcers. Large or deep skin ulcers put you at risk of gangrene or foot amputation. The best way to tackle this is:

  • Get into the habit of checking your feet daily
  • See a chiropodist for corns, calluses, and toenail cutting
  • Get medical attention immediately if you see infections or ulcers developing

Skin problems in diabetics are caused by damage to small blood vessels. Most commonly dry skin and loss of elasticity occur due to neuropathy and a poor blood supply. This also means you sweat less so your skin is not protected by sweat and natural oils that keep your skin supple. Also, fungal infections are commonly seen in people with diabetes. Fungus likes moisture and high glucose levels.

Diabetes and heart disease

Diabetes and heart disease are undoubtedly linked. You are twice as likely to have heart disease or a stroke than non-diabetics. Cardiovascular disease is the number one cause of death in people living with diabetes. For this reason, doing all you can to prevent this problem from developing is essential. Make heart-healthy choices for instance:

  • Give up smoking
  • Keep your blood pressure under control
  • Pay attention to your cholesterol levels
  • Improve your diet
  • Exercise – moderately

Diabetic eye problems

Diabetic eye problems are the leading cause of vision loss among adults aged 20-74 in the US. For this reason, you must attend regular eye tests to prevent complications associated with diabetes. Eye tests are done by opticians or specialist ophthalmologists.

Cataracts

The buildup of sugar in the lens of your eye makes you prone to cataracts. It makes the lens of your eye cloudy, limiting the amount of light reaching the back of your eye. It is particularly bothersome in bright light. A simple operation to replace the damaged lens can be done, usually within a day. The results are generally excellent.

Glaucoma

Glaucoma is a build-up of pressure in your eye. High pressure can damage your optic nerve leading to gradual loss of sight. Diabetics are two times as likely to develop glaucoma than people without diabetes. Medical treatment can lower the pressure and save your eye.

Diabetic retinopathy

Both cataracts and glaucoma respond to treatment well. Diabetic retinopathy is more complicated and less treatable than the other conditions.

The retina at the back of your eye has a unique structure. The middle area allows you to see color and fine detail. The outer area picks up black and white allowing you to see in the dark. High sugar levels can damage the smaller blood vessels which supply the retina. They become weaker and small blisters can form that eventually burst, forming hard lumps. This is a sign that the blood supply to your eye is not as good as it should be. These hardened areas become yellowish in color and can last for years. This process causes your vision to become weaker.

Macular edema

Macular edema is a result of diabetic retinopathy. Fluid from your retina flows into the central structure of your eye (macular) by the process described above. This causes swelling of your eye and loss of vision. Laser treatment could be an option for diabetic retinopathy but has not been so successful for macular edema.

Diabetes and oral health

People with diabetes have a high risk of gum disease. If not treated it can cause your teeth to loosen or fall out. The early stages are not very noticeable. Your dentist will be the first one to point them out. Therefore regular dental checkups are essential.

Diabetes and hearing loss

Experiencing hearing problems is common for diabetics as the condition causes damage to nerves in the ear. Nerves in the inner ear can be damaged by high blood sugar and low blood sugar slows down the nerve signal from the inner ear to the brain.

Diabetes and Alzheimer’s

The risk of developing dementia may be increased by type 2 diabetes. Important research is needed into this as the full risks of developing dementia are not known.

Diabetes and depression

Dealing daily with diabetes can be challenging and people with diabetes are more likely to have depression than people without the condition. Having a mental health issue can make it harder to follow your treatment plan and take good care of yourself. If you are concerned about your mental health speak to your doctor. There is help available.

Gestational diabetes complications

A whole new group of important considerations arises during pregnancy. Gestational diabetes is a type of diabetes first seen in pregnancy for a woman who did not have diabetes before pregnancy. If you already have pre-gestational diabetes or develop gestational diabetes you will need to be aware of how to keep yourself and your baby healthy. To begin with, you should aim to be in the best possible health possible before conceiving. Equally important, your blood glucose level should be under control. In the long run, this will lead to a much smoother pregnancy.

Complications for the baby

Gestational diabetes can bring about the following complications in your baby:

  • Excess growth
  • Type 2 diabetes later in life
  • Low blood sugar
  • Death

Complications for the mother

Gestational diabetes can lead to the following complications for the mother:

  • Preeclampsia – high blood pressure during pregnancy and after labor
  • Future pregnancies with gestational diabetes

Outlook

You may be feeling concerned or even alarmed by the complications caused by diabetes. The good news is that by controlling your diabetes you can improve the outlook of complications enormously.

How to prevent diabetes complications

Above all, you need to commit to making changes in the long term to prevent diabetes complications. By and large, the steps you need to take are simple and basic. You need to follow a healthy eating plan, exercise regularly, and maintain a healthy body weight. It is important to keep blood glucose levels under control and take medication regularly. Also, attend your annual and regular checks with your healthcare team. It is possible for you to thrive with diabetes and not just live with it.

Complications of diabetes FAQs

What is the most common complication of diabetes?

There are several long term complications that can develop from diabetes. Heart disease is the number one cause of death in diabetics. Other chronic conditions which may develop if left without treatment include damage to nerves, retinopathy, gum disease, heart attacks, strokes, and sexual problems.

How do you feel when your blood sugar is too high?

High blood sugar is also known as hyperglycemia. Generally, there are two reasons this happens. Either your body does not have enough insulin or it cannot use the insulin it makes properly. The following symptoms occur:

  • Headaches
  • Blurred vision
  • Excessive thirst
  • Frequent urination
  • Fatigue
  • Weight loss

What are the three main diabetic emergencies?

  • Diabetic ketoacidosis – this occurs if your body is unable to produce enough insulin and starts to break down fat instead, causing ketones (blood acid build-up) to enter your bloodstream
  • Hyperosmolar Hyperglycemic Nonketotic Syndrome HHNS is typically caused by an infection or illness, resulting in rising blood sugar levels
  • Hyperglycemia without ketosis the body can reach extremely high levels of blood sugar without ketones 

At what sugar level should I go to the hospital?

The American Diabetes Association advises immediate hospital action if your blood sugar level is above 240mg/dL and ketones are present.

Is type 1 diabetes worse than type 2 diabetes?

No, neither type 1 diabetes or type 2 diabetes is worse than the other. Above all, how soon your diabetes was diagnosed, the progress of your diabetic complications, and any other medical conditions play a larger role in your diabetes.

Alcohol and diabetes

After a diabetes diagnosis, some people decide to give up alcohol but this will not suit everyone. It is important to follow some rules if you decide to drink alcohol. Alcohol can make some of the complications of type 1 diabetes and type 2 diabetes worse. Understanding what you are drinking and how alcohol changes your blood glucose levels is particularly important when you have diabetes.

The American Diabetes Association recommends you ask yourself three questions before drinking alcohol with diabetes:

  • Is my diabetes in good control?
  • Does my doctor agree that I can have alcohol?
  • Do I know how alcohol can affect me and my blood sugar?

How alcohol affects diabetes

Alcohol interacts with diabetes medications causing low blood sugar (hypoglycemia). When you drink alcohol your liver will choose to remove the alcohol in your body over maintaining your blood sugar level leading to hypoglycemia. Low blood sugar makes you drowsy, confused and causes difficulty walking which are also signs of being drunk. The confusion of being drunk or hypoglycemic can be very unsafe. A low sugar episode (hypoglycemia) could go unnoticed if you are drunk. Moderate amounts of alcohol may cause blood sugar to rise but excessive alcohol can actually decrease your blood sugar levels.

Alcohol is an appetite stimulant, so you may end up eating more calories and making less positive food choices. The calorie content of alcoholic drinks can be high and the nutrient content low, leading to an increase in calorie intake and weight gain.

Alcohol can also play a part in diabetic nerve damage, diabetic eye disease, and high blood triglycerides leading to complications.

Alcohol-induced hypoglycemia

Normally, the liver releases glucose to maintain blood sugar levels. When you drink alcohol your liver works to remove the alcohol from the blood instead of stabilizing your blood sugar levels. This can lead to dangerously low blood sugar levels in the body when you are a diabetic.

Symptoms of low blood sugar are similar to the symptoms of too much alcohol:

  • Drowsiness
  • Confusion
  • Lack of coordination
  • Passing out

In the long run, it is a sensible idea to inform friends and family about your diabetes so they do not mistake these symptoms for you simply being drunk. If you pass out those around you need to know that this is a medical emergency.

Your liver takes roughly 1 to 1.5 hours to break down 1 alcoholic drink. For that entire time, your risk of low blood sugar exists. Imagine if you have two drinks, the time is doubled to 2-3 hours, that you are at risk for low blood sugar levels. In short, the more alcohol you drink the higher the risk for dangerously low blood sugar levels.

How to drink alcohol safely

Some tips to stay safe while drinking alcohol:

  • Drink moderately. The American Diabetes Association describes moderate drinking as 1 drink for women per day and two drinks for men per day. One drink is equal to 1 1/4 oz of liquor, 12 oz of beer, or 5 oz of wine.
  • Drink alcohol with or just after food. The meal or snack should contain carbohydrates. Food slows down the rate at which alcohol is absorbed into the bloodstream.
  • Keep track of the amount you are drinking.
  • Track the alcohol and sugar content of your drinks.
  • Drink slowly and pace yourself.
  • Check your blood sugar levels before, during, and after drinking. You will have a clearer idea of how your body is responding.
  • Inform the people you are drinking with about your diabetes. The people around you need a good understanding of your condition to help you if needed.
  • Wear a medical alert piece of jewelry that says you have diabetes. This will inform people around you immediately about your condition in an emergency.

What can I drink?

The best types of alcohol for people with diabetes are those with low sugar or carbohydrate content, some examples are shown below.  Remember that it is not just sugar that interferes with your blood sugar levels but the alcohol itself. Moderation is the key. You must be aware that continuing to drink while struggling with diabetes can be detrimental to your health.

  • Low carb beer options such as; Miller Light (3.2 grams of carbs per 360ml bottle), Corrs Light (5 grams of carbs per 360ml bottle), Bud light (4.6grams of carbs per 360ml bottle), and Busch Ice and Busch Light (4.2 and 3.2 grams carbs respectively).
  • Red wine has a high antioxidant content which can provide heart health benefits. A 150ml serving of red wine gives 3.8 grams of carbs.
  • White wine, particularly champagne has a low carb content. The brut variety gives 1.7grams of carbs per 150ml and the extra brut contains 0.8grams of carbs per 150ml drink.
  • Hard liquors such as gin, vodka, rum, and whiskey when consumed on their own contain zero grams of carbs. If they are consumed with sugary mixers or sodas they can increase your blood sugar.
  • Traditional cocktail recipes are loaded with syrups and sugar making them unsuitable for diabetics. If cocktails are your drink of choice then opting for low sugar varieties will be better. A Martini made by mixing gin or vodka with dry vermouth in a 2-to-1 ratio will provide 0.2 grams of total carbs per 120-mL drink. A Vodka soda using club soda, or seltzer containing zero carbs is another option for cocktail lovers.

Before drinking you should know what a serving size is and how many calories and carbohydrates are in that serving. According to the USDA, the table below lists the calories and carbohydrates in commonly chosen alcoholic beverages:

BeverageServing sizeCarbohydrate (grams)Calories
Beer
Regular beer12 oz13150
Light beer12 oz5100
Non-alcoholic beer12 oz1260
Wine
Dry White, Red, Rose4 oztrace80
Sweet wine4 oz5105
Wine cooler12 oz30
Sparkling Wines
Champagne4 oz4100
Sweet kosher wine4 oz12132
Distilled Spirits
80 - proof
Gin, Rum, Vodka, Whiskey, Scotch
1.5 oztrace100
Dry Brandy, Cognac1 oztrace75
Cocktails
Bloody Mary5 oz5116
Daiquiri5 oz10281
Gin & Tonic7.5 oz16170
Manhattan2 oz2178
Margarita6 oz29205
Martini2.5 oztrace156
Pina Colada4.5 oz32245
Whiskey Sour3.5 oz14162
Mixers
non-caloric mixers (mineral water, sugar0free tonic, club soda, diet soda)any00
Tonic water4 oz1141
Tomato juice, Bloody Mary mix4 oz525
Juice ( orange, grapefruit, pineapple)4 oz1560

Alcohol and diabetes FAQs

Can drinking alcohol cause diabetes?

Excessive alcohol intake increases your chance of developing chronic inflammation of the pancreas called pancreatitis. This condition leads to permanent damage to the pancreas and its ability to manage the production, storage, and release of insulin. Pancreatitis can harm the ability of the pancreas to secrete insulin, which can potentially lead to type-2 diabetes. However, there are several other risk factors for type 2 diabetes including, your family history, age, and ethnic background. You are also more likely to develop diabetes if you are overweight. If you’re planning to drink alcohol and you have diabetes, aim to always stay within the recommended guidelines. This is the safest way to drink alcohol.

Can I drink alcohol while taking metformin?

When alcohol and metformin are taken together two things may happen to you; hypoglycemia or lactic acidosis. The symptoms of hypoglycemia may be life-threatening if not picked up quickly as they can be confused with being drunk. Lactic acidosis is rare but can result in a build-up of lactic acid in the body causing damage to the heart, kidneys, lungs, and blood vessels.

You should avoid the combination of metformin with excessive alcohol. Moderate drinking of  1 drink for women per day and two drinks for men per day is a sensible option when taking metformin.

Is red wine ok for diabetics?

Red wine is ok for diabetics, but moderation is the key. Red wine has been shown to reduce heart disease with well-controlled type 2 diabetes. In one study the participants were given either one glass of red wine, one glass of white wine, or a glass of water each day for 2 years. They were asked to follow a Mediterranean diet and ignore calorie intake.  At the end of the study, in comparison to the other groups, the red wine group had lower cholesterol levels and higher levels of good cholesterol (HDL), which we know is better for your health.

What alcohol is the lowest in sugar?

Tequila, gin, vodka, brandy, whiskey, and rum are the lowest in sugar. Spirits can be seen as sugar-free because they contain zero carbs. They are drunk in small volumes so the calorie content of these drinks is low.  Mixers such as fizzy drinks change the sugar content of spirits, something you need to watch out for. Drinking spirits neat, in moderation, is your best option!

What beer has no sugar?

Beers are generally low in sugar and contain oligosaccharides which is a type of sugar the body finds difficult to break down. The flip side is they tend to be high in calories and high in carbohydrates. Beers differ in sugar content depending on their differences in the fermentation process. For example, regular beers tend to be sugar-free, light beers have around 1 gram of sugar per can and non-alcoholic beers tend to usually have the highest sugar content of all.

Type 1 vs type 2 diabetes

What is the difference between type 1 and type 2 diabetes? You may already know that more than one form of diabetes exists, but Type 1 and type 2 diabetes are two separate conditions with some similarities. Each has its own symptoms, causes, and treatments. Diabetes arises when a person cannot make enough insulin or the insulin a person makes is ineffective at controlling blood sugar levels. The end goal for both types of diabetes is to keep blood sugar levels stable and reduce complications.  Let us take a look into both of these forms of diabetes.

How many people have diabetes?

The Centers for Disease Control and Prevention reports that more than 34 million people have diabetes in the US, of which 90-95% have type 2 diabetes and the remaining 5-10% have type 1 diabetes. Men and women develop diabetes at around the same rate. However, significant differences are seen among different races and ethnicities.

What are the causes of type 1 and type 2 diabetes?

The most important hormone to understand in diabetes is insulin. It is made in your pancreas which is located just behind your stomach.

Without getting too medical, insulin travels in your blood through your body. It opens up cells in your body so that glucose can enter them. After glucose enters cells, the cells immediately use it for energy in the form of glycogen or convert it to fat for use later. When glucose leaves your blood and enters cells, your blood glucose level falls. Your pancreas detects your glucose falling and turns off the release of insulin. This stops your blood sugar from going too low (hypoglycemia). At the same time, your liver begins to make more glucose in your blood.

This whole system in the body keeps the correct level of glucose. Insulin is the only means that the body has of lowering blood glucose levels. When this system fails diabetes occurs. Each type of diabetes involves the pancreas not functioning properly.

Type 1 diabetes

In type 1 diabetes you do not produce insulin. This is because your body mistakes your own healthy cells as foreign invaders and attacks the cells that produce insulin in the pancreas. Once these cells are attacked they are unable to produce insulin. We do not currently know why the immune system in type 1 diabetes does this but research is ongoing. Type 1 diabetes starts most commonly in younger patients but can occur at any age.

Type 2 diabetes

In type 2 diabetes you do produce insulin, but the body can not use it effectively. There is usually a combination of a part failure of insulin production and a reduced response to the hormone. This is known as insulin resistance. Research does not give us a clear idea why some people develop this and others don’t, but lifestyle factors, e.g. lack of exercise and excess body weight can contribute to type 2 diabetes.

What are the risk factors for type 1 and type 2 diabetes?

Type 1 diabetes risk factors include:

  • Parent or sibling with type 1 diabetes
  • Most commonly seen in children and younger people
  • Genetics affects the way the body produces or uses insulin
  • Exposure to some infections or viruses

Type 2 diabetes risk factors include:

  • Aged over 40 years
  • Smoking
  • Excessive belly fat
  • Physically inactive
  • Unhealthy diet
  • Gestational diabetes during pregnancy
  • Slightly raised blood glucose levels
  • Pre-diabetes
  • Immediate family member with type 2 diabetes
  • Polycystic ovary syndrome
  • Ethnicity group – Black, Hispanic, Native American Indian, Alaskan Natives, Pacific Islanders, and some people of Asian origin

What does diabetes do to the body?

Having diabetes means that glucose builds up in your bloodstream to a dangerous level. If this level is not reduced by medication and lifestyle changes eventually the body will be damaged. High glucose levels lead to complications such as kidney disease, foot problems, eye problems, and heart disease.

Type 1 vs type 2 diabetes symptoms

Type 1 diabetes symptoms:

  • Frequent urination
  • Increased thirst
  • Increased hunger
  • Blurred vision
  • Fatigue
  • More frequent infections
  • Weight loss
  • Dry skin
  • Slow-healing sores
  • Stomach pains, nausea, or vomiting

Type 2 diabetes symptoms:

  • Frequent urination
  • Increased thirst
  • Increased hunger
  • Blurred vision
  • Fatigue
  • More frequent infections
  • Numbness in hands, feet, or legs
  • Genital itching
  • Obesity

The signs and symptoms of type 1 and type 2 diabetes are similar but there are some differences:

  • Age of onset –  Type 1 diabetics are usually younger than type 2 diabetics
  • Weight –  Type 1 diabetics are likely to be normal weight but obesity is common in type 2 diabetics
  • Onset –  Type 1 diabetics have a sudden onset of diabetes but type 2 diabetics have slow progressing symptoms

How are type 1 and type 2 diabetes diagnosed?

Tests to diagnose both type 1 and type 2 diabetes

  • Fasting blood sugar test – After an overnight fast your blood glucose level will be measured
  • Glucose tolerance test – After an overnight fast your blood glucose level will be measured, followed by a drink containing glucose. Your blood sugar will then be retested every half hour for two hours to see how your body is responding
  • Random blood sugar test – This test does not require an overnight fast but is taken any time of the day
  • Hemoglobin A1c test – As a diabetic, you definitely need to know about this. Hemoglobin A1c measures the average blood sugar control over the last two to three months. When glucose attaches to hemoglobin in the bloodstream it is called Hemoglobin A1c. The more glucose in the blood, the more hemoglobin A1c forms. This form of hemoglobin remains in the blood for 2-3 months therefore it gives a good reflection on what is going on in the body rather than a single snapshot result. A1C test results are reported as a percentage. The American Diabetic Association diagnose diabetes as an A1C of greater than or equal to 6.5%

Type 1 vs Type 2 diabetes diagnosis chart

ResultA1c
NormalLess than 5.7%
Pre-diabetes5.7%-6.4%
Diabetes6.5% or higher

Test to diagnose type 1 diabetes only

  • Autoantibodies test – A blood test without fasting to look for autoantibodies linked with type 1 diabetes
  • Ketones test – A urine test to measure ketones

Type 1 vs type 2 diabetes treatment

Type 1 diabetes treatment                                                                                                                                                                                                                              

The only treatment for type 1 diabetes is insulin. If you have this type of diabetes your body is unable to produce insulin therefore you need to inject it directly into the body. As a result, there is no cure for type 1 diabetes. Insulin finely controls the amount of glucose in your blood. It allows glucose to enter cells so they can use it for energy and function. Insulin also plays an important role in growth in three main ways. Firstly by supporting fat and muscle to form. Secondly by allowing the storage of glucose in a form called glycogen for use when fuel isn’t coming in. Finally it blocks the breakdown of protein.

If you have type 1 diabetes you will inject insulin directly into soft tissue such as the stomach, upper arm, or buttocks several times a day. You have different ways to inject insulin, such as using a syringe, insulin pen, insulin pump, and jet injections. These are some of the most common brands of insulin available in the US:

Type 2 diabetes treatment

The first recommended treatment for type 2 diabetes is typically lifestyle changes, such as losing excess weight, getting regular exercise, and eating a healthier diet. If lifestyle changes do not work, then you may be prescribed medications to help lower your blood glucose. Most medications for type 2 diabetics are oral drugs. However, a few come as injections. Some people with type 2 diabetes may also need to use insulin. A wide variety of diabetes medications are available, these are some of the most common:

SGLT2 (Sodium-glucose transport protein 2) inhibitors examples include:

DPP-4 (Dipeptidyl peptidase 4) inhibitors examples include:

Alpha-glucosidase inhibitors examples include:

Glucagon-like peptides examples include:

Biguanides -the most common biguanide is metformin, examples include:

Meglitinides examples include:

  • Starlix
  • Prandin

Sulfonylureas examples include:

Can diet help type 1 and type 2 diabetes?

At its core, diabetes is all about how your body deals with the food and drink you consume. Changing your diet can help to reduce how much glucose is released into your blood at a time, and it can help improve insulin resistance.

Diet and type 1 diabetes

If you follow your treatment plan and take your insulin, you can eat a normal diet and there are no foods you need to avoid. Eating a healthy diet and keeping your weight down can lessen the risk of diabetes complications such as heart disease and stroke.

Diet and  type 2 diabetes

Changing your diet can be an effective way to control and manage type 2 diabetes. Eating a poor diet can increase your weight, blood pressure, and cholesterol. A diet high in fat, sugar, and refined carbohydrates may also contribute to insulin resistance. Making the right food choices can have a significant effect on your condition.

How to prevent type 1 and type 2 diabetes?

Unfortunately, type 1 diabetes can not be prevented. You may lower your risk of developing type 2 diabetes by lifestyle changes and developing new routines, such as:

  • Keeping to a healthy weight
  • Increase your activity levels
  • Eating a healthy diet
  • Reduce smoking

What is the outlook for people with type 1 and type 2 diabetes?

Diabetes is a chronic disease but on the whole, the prospects for someone with diabetes are better than ever before. A better understanding of diabetes and improvements in treatments can give you confidence that you really can be in control of your diabetes. It is equally important to take responsibility for your health by:

  • Paying close attention to your diet
  • Carrying out regular tests on your blood and urine to track your progress
  • Making time for exercise
  • Educating yourself about diabetes
  • Taking your medications routinely
  • Keeping a positive attitude

Type 1 vs type 2 diabetes FAQs

Which is worse, type 1 or type 2 diabetes?

It is sometimes thought that type 1 diabetes is worse as it starts suddenly and you need to inject insulin. On the other hand, type 2 diabetes starts much less dramatically and can initially be treated with lifestyle changes. Given that both types of diabetes have their challenges and complications one type can not be classed worse than the other.

Is type 1 or type 2 diabetes curable?

Type 1 and type 2 diabetes are lifelong conditions that can be significantly improved but not cured. You can reverse diabetes symptoms for some time, but there is always the chance they could return. Meal planning, healthy eating, exercising, and maintaining a healthy weight are essential habits to keep diabetes symptoms away. “Reverse” does not mean a forever cure. Diabetes is an ongoing disease.

Can type 2 diabetes turn to type 1?

No. Type 2 diabetes can not turn into type 1 diabetes since the two conditions have different causes.

How long can type 1 diabetes go untreated?

Type 1 diabetes can go untreated until you notice bothersome symptoms that lead to a blood sugar test by your doctor confirming a diagnosis. Untreated type 1 diabetes can cause heart disease, stroke, as well as eye and kidney diseases.

Can you get type 1 diabetes later in life?

Yes. Type 1 diabetes typically occurs in children and teens but can occur in adult life too. As an adult, it is not as straightforward to diagnose type 1 diabetes as the symptoms take longer to appear.

Best insulin injection sites

Insulin is your best friend if you have type 1 diabetes. If you are a type 2 diabetic you may need insulin later in your life. Injecting insulin is the only effective way of getting it into your bloodstream. Taking insulin orally as a tablet is not an option as it is partially destroyed by digestive juices and becomes less active.

There are generally five different forms of insulin:

  • Fast-acting – Apidra, Humalog, and Novolog. These begin to work about 15 minutes after injection
  • Short-acting (regular) – Humulin R and Novolin R. These begin to work within 30 minutes after injection
  • Intermediate-acting – Humulin N and Novolin N.  Generally these work two to four hours after injection
  • Long-acting – Levemir, Lantus, and Tresiba. Work several hours after injection
  • Premixed insulins – Novolog 70/30. Contains a combination of intermediate-acting insulin with regular insulin

Types of insulin injection

Several different devices are available to deliver insulin into your body. Let us take a look at these:

  • Syringe
  • Insulin pen
  • Insulin pump
  • Jet injections

Your diabetes team will help you decide which method is best for you. Additionally, they will show you how to give yourself the injections and explain how the equipment works.

Syringes

Injection by needle or syringe is a traditional but popular way to insert insulin into your body. A vial and a needle are the two basic requirements. You use the needle to draw up the insulin through the vial and inject. Novolog is an option with this method. Insulin needles and syringes come in different sizes depending on the dose of insulin you need.

Insulin pens

Another popular choice is insulin injection pens. They are both convenient and portable. Pens are straightforward to use and deliver accurate dosing. There are several types to choose from but on the whole, they are all quite similar. The Novolog Flexi-pen and the Humalog kwikpen are possible options. It is simply a matter of which suits you best.

Insulin pumps

An insulin pump works by providing a continuous flow of insulin through a thin tube and needle. It is placed underneath the skin on your abdomen. It is attached to a small computerized device the size of a deck of cards. The pump provides a changeable but constant background insulin dose almost like how your body normally would.

Insulin pumps use short-acting and rapid-acting insulin. Long-acting insulin is not used since the pump is programmed to deliver a small amount continuously to keep your blood sugar levels even. Pumps require a lot of input from patients alongside training to use the device correctly. Apidra and Humalog can be used in a pump device.

Jet injectors

You hold the device close against the skin and push a button that releases a jet of air that forces insulin through the skin due to the high pressure. The injection device takes in a large quantity of insulin, enough for multiple insulin treatments. You measure the amount of insulin delivered by rotating one part of the device.

Where to inject insulin

Where you inject the insulin helps determine how fast it works. You need to inject insulin under your skin rather than into a vein or muscle. The fatty tissue just under your skin is the ideal place for insulin to be absorbed gradually. If you inject the insulin deeper into your muscle your body will absorb it too quickly.  The effects may not last long and will additionally be more painful. Judging the depth correctly can be quite difficult, particularly if you are slim but it is important to master the technique to stay safe. The following areas are likely to have enough body fat to allow you to easily inject insulin:

insulin injection sites

Abdomen

This part of your body is easy to reach and insulin is absorbed more quickly and predictably in the abdomen. The area between the waist and the hipbones, about 2 inches away from the belly button is the best location. Areas around scars, moles, or skin blemishes should be avoided.

Thigh

Around 4 inches down from the top of your leg and 4 inches up from your knee is the ideal location.  Inject into the top and outer areas of your thigh. In this area the insulin is absorbed slowly. The inner thigh should be avoided as blood vessels are concentrated in that area.

Upper Arms

The fatty area on the back of your arm, between your shoulder and elbow, is another area suitable for injection. You need to inject into your less-used arm i.e. a right-handed person will inject into the left arm and vice versa. However, it can be tricky to reach on your own. Insulin is absorbed in a moderate speed from this site.

Lower back, hips, or buttocks

Draw an imaginary line across the top of the buttocks between the hips. This will give you a guide to the area best suited for injection. You must avoid injecting into the lower part of the buttocks.  Like the upper arms, this is also a difficult area to reach on your own. Insulin is absorbed slowest from this site.

Rotating insulin injection sites

The importance of rotating insulin injection sites is to maintain effective insulin absorption. Small fatty lumps or hard lumps could develop in areas that are continuously used as sites. These can interfere with insulin absorption and also cause discomfort. Switching between injecting sites, for example, left and right arm or right and left thigh, and moving injection sites within the area will help prevent problems.

How is insulin absorbed?

The site of the insulin injection is important because this decides how fast the insulin can work.

  • Abdomen – Insulin enters the bloodstream fastest here after an abdominal injection
  • Upper arms – The body absorbs insulin with moderate speed but slower than an injection in the abdomen
  • Lower back and thighs – Insulin enters the bloodstream slowest from these sites

How to inject insulin

  1. Gather together all your supplies – insulin, needle, syringe, and alcohol wipes
  2. Wash your hands with soap and water. Dry your hands thoroughly
  3. Clean your skin where you will inject the insulin with an alcohol wipe
  4. Roll the insulin bottle between the palms of your hands
  5. Draw the correct dose with the needle
  6. Take a fold of your skin. Pinch the skin and fat between your thumb and first finger
  7. Inject the needle at a right angle and push the insulin in
  8. Pull out the needle. Apply pressure on the site for 5-10secs
  9. Throw away your used inulin syringe carefully

Insulin injection sites complications

As part of your self-management care, you should be aware that lipo (lipohypertrophy) can be a complication with insulin injection sites:

  1. A lump or swelling under the skin where insulin has been repeatedly injected
  2. Fat and scar tissue form in these areas and become rubbery
  3. Insulin absorption in these areas can reduce or increase

If you develop lipo you are at a higher risk of unexplained low blood sugar, high blood sugar, or diabetic ketoacidosis.

Our do’s and don’ts for injecting insulin

Do’s:

  • Rotate the injection site if keeping the body part consistent
  • Inject insulin into the fatty area under the skin
  • Numb your skin with ice before swabbing it with alcohol
  • Wait for the alcohol to dry before injecting
  • Ask your doctor for a chart to track your injection sites
  • Recognize the warning signs of high blood sugar symptoms and low blood sugar symptoms

Don’ts:

  • Inject into roots of body hair
  • Stick to the same delivery device if it is not working for you
  • Store insulin incorrectly – you must store opened or unopened insulin at room temp for 1 month only

Safe needle disposal

Safe needle disposal is an important responsibility for a diabetic. This will be discussed with you by your healthcare provider. Regulations and procedures vary by location. Find out what your state requires by calling the Coalition for Safe Community Needle Disposal at 1-800-643-1643, or visit their site at http://www.safeneedledisposal.org 

Insulin injection sites FAQs

Where should you not inject insulin?

Insulin should not be injected into the muscle.  Also, do not inject insulin into areas where you have a wound or bruising.

What angle is insulin injected?

Patient information given by the American Diabetes Association advises the needle is inserted straight in at a 90-degree angle. You do not have to pinch up the skin unless you are using a longer needle (6.8 to 12.7 mm). Small children or very thin adults may need to inject at a 45-degree angle. Insulin should go into a fatty layer of your skin called the subcutaneous tissue.

How many units of insulin is normal?

You and your doctor will decide the best schedule and insulin dose for you. Your doctor may work out your first dose based on your weight. If you take long-acting insulin your doctor may work on 0.2 units for every 2.2 pounds. This may go up by 2-4 units every 3 days based on your target blood sugar level.

How can I get insulin without a needle?

An inhaled insulin product called Afrezza is available. Afrezza is a rapid-acting inhaled insulin that is administered at the beginning of each meal. It can be used by adults with type 1 or type 2 diabetes.

What size needle is used for insulin?

Needle size lengths for insulin available are 4mm, 6mm, 8mm, 10mm, and 12mm. Your doctor will advise you on the most suitable length for you.

Is it OK to inject cold insulin?

Manufacturers recommend storing your insulin in the refrigerator however injecting cold insulin can sometimes make the injection more painful. To avoid this, store the bottle of insulin you are using at room temperature. Insulin kept at room temperature will last approximately one month.

Is the keto diet good for diabetics?

It’s important to know that the American Diabetes Association (ADA) does not recommend any single diet over another to control your diabetes.

As an individual with different dietary needs, blood sugar levels, and target weight goals your diet needs to be tailor-made. Your focus should be to follow a healthy, balanced diet with plenty of fruit and vegetables. Carbohydrates should be spaced out over the day. Smaller meals should be eaten more often alongside following a personalized diet plan. Personalized diet plans can be created with your doctor or dietitian to make sure you follow a diet that’s suitable for you. In the following blog, we will go into more detail about one of the most talked-about diets surrounding diabetes, the keto diet, to help you make an informed decision for your health.

What is keto?

Keto is the shortened term for the full scientific word ‘ketosis’.

What is the keto diet?

The ketogenic (keto) diet, sometimes known as the keto plan, is high in fat, moderate in protein, and low in carbohydrates and can potentially change the way your body stores and uses energy. Eating more fats and protein and fewer carbohydrates causes our body to switch to using fat for fuel instead of burning sugar. This switch produces ‘ketones’ and reduces blood glucose levels. As glucose drops and ketone levels rise in the bloodstream, the body stops burning sugar and instead uses the ‘ketones’ as an alternative fuel. This is called being in ‘ketosis‘. A ketogenic diet may improve blood glucose (sugar) levels while also reducing the need for insulin, however, it does come with some risks that will be looked at later.

How does the keto diet affect diabetes?

Keto and diabetes are often talked about together because of the benefits this type of diet can bring to a diabetic:

  • The ketogenic diet has the potential to decrease blood glucose levels
  • Managing carbohydrate intake is often recommended for people with type 2 diabetes
  • It may help some people with type 2 diabetes because it allows the body to maintain glucose levels at a low but healthy level
  • Some people with type 2 diabetes who also follow a ketogenic diet may be able to reduce their need for medication
  • Beneficial to a person who is trying to lose weight

How to follow a keto diet

A low-carb diet is when you eat 100-150 grams of carbs per day. The keto diet goes even lower than this because the goal is to get into ketosis. Typically between 20-50 grams of carbohydrates is the goal for a keto diet. The nutrient breakdown on a ketogenic diet typically works out to be 70-75% of calories from fat, 20-25% from protein, and 5-10% from carbohydrates daily. 20-50 grams of carbohydrates can easily slip into your diet without you realizing it, so tracking your food with an app on your phone is a helpful way to keep you within your carbohydrate intake limit.

Ketogenic diets should consist of the following types of food:

  • Low-carb vegetables e.g. broccoli, kale, spinach
  • Eggs
  • Meat e.g. lamb, chicken, beef
  • Healthy fats e.g. avocados, flaxseeds
  • Fish e.g. mackerel
  • Berries e.g strawberries, raspberries

The most important carbs on a keto diet are green leafy vegetables as they are alkaline. As the ketogenic diet is acidic, green leafy vegetables help with reducing acidity in the body. You can add small amounts of berries and other low glycemic index fruits, but be careful you do not add too much.

Your focus when choosing fats for the keto diet should be heart-healthy fats such as salmon, avocado, nut butter e.g almond butter, nuts, eggs, cottage cheese, and seeds such as flaxseeds.

Keto diet risks

  • Changing your body’s primary energy source from carbohydrates to fat causes an increase in ketones in the blood
  • When you have too many ketones you may be at risk of developing diabetic ketoacidosis (DKA)
  • Short term side effects such as constipation, leg cramps, headaches
  • Long term side effects such as kidney damage, cardiovascular disease, and an increase in hypoglycemic episodes

Monitoring your diabetes

Your doctor will need to monitor both your blood glucose and ketone levels to make sure that your diet is not causing any negative effects. A high-fat diet needs to be closely monitored with regular testing and medication adjustments. Your doctor will be able to advise you on the most suitable testing plan for you.

Alternative diets for diabetics

The best diet for diabetics is not a straightforward answer. Keto diets may be the best for some people and other alternative diets may suit others better.

  • Plant-based diets for diabetics focus on eating food such as whole grains, beans, legumes, rice, and unprocessed breakfast cereals. The findings of a 2019 Harvard T.H. Chan School of Public Health study found that individuals who follow a plant-based diet lowered their risk of type 2 diabetes by 23%.
  • Mediterranean diets for diabetics contain a large amount of fish, whole-grain bread, fruits, vegetables, olive oil, herbs, and spices. There is evidence that the Mediterranean diet can help with weight loss.
  • Paleo-based diets for diabetics are based on eating foods from the earth. This diet contains fish and meat, vegetables and fruit, nuts and seeds, and some starchy plants.

There is no simple answer to which diet is best for a diabetic. The keto diet and alternative diets all need strict medical supervision.

Keto diet and diabetes FAQs

Can keto reverse diabetes?

Keto diets can lead to short-term improvements but strictly restricted dieting is unnatural and not sustainable for humans.  There are still many benefits of following low-carb diets, which include improved blood glucose control and reduced reliance on medication. This means lower doses of medication or less need to take the stronger medications that have greater side effects.

What is the one food that kills diabetes?

One food or food group alone can not kill off diabetes in the body. It is a combination of a controlled diet under the supervision of your doctor, exercise, and a healthy lifestyle. There is no cure for diabetes.

How long does it take to reverse diabetes on the keto diet?

A new study in The BMJ found that sticking to a low carb diet for six months showed higher rates of diabetes reversal with people who had type 2 diabetes.

Why is my blood sugar high when I don’t eat carbs?

Diabetes is a disease in which the body can not lower blood sugar levels. Diabetics are unable to break down glucose into energy. This is because there is not enough insulin to move the glucose (type 2 diabetes) or the insulin produced does not work properly (type 1 diabetes). Once the production of insulin slows or stops, your blood sugar remains high all the time. When you have diabetes your blood sugar can be high no matter when you had last eaten, because the glucose metabolism process isn’t working properly.

How do you lose belly fat on keto?

Carrying too much belly fat is harmful and has a strong link with diabetes. The keto diet is a good way to reduce belly fat alongside reducing your total weight and overall body fat much more than a low-fat diet. Follow our simple advice above to get started losing belly fat on keto.

How many carbs should a diabetic have in a day?

Studies show that restricting carbs may benefit people with diabetes. The lower your carb intake the greater the effect on your blood sugar levels and other health benefits. Again, carb intake is extremely individual and it also depends on the diet you are following. Please speak to your doctor to discuss the appropriate amount of carbs you should be eating.

Diabetes medications

Having a good grasp of the medication you are taking and how it works gives you more confidence in managing your diabetes. The number of medications available to treat type 2 diabetes in particular, is long and confusing at first. No single diabetes treatment is best for everyone and what works for one person may not work for another. Let us take a look at the various diabetes medications available, simplify how they work, and what common side effects they may have. This knowledge will allow you to discuss treatment options available with your doctor.

Type 1 diabetes medications

When you have type 1 diabetes the only choice of medication is insulin. If you have type 2 diabetes you may use insulin injections if diet and tablets are not working for you.

Insulin

There are different types of insulin but the basic difference is in how quickly they take effect, so they can be divided into:

  • Fast-acting – Apidra, Humalog, and Novolog, begin to work about 15 minutes after injection
  • Short-acting  (regular) – Humulin R and Novolin R work within 30 minutes after injection
  • Intermediate-acting – Humulin N and Novolin N generally work two to four hours after injection
  • Long-acting – Levemir, Lantus, and Tresiba works for several hours after injection
  • Premixed insulins – Novolog 70/30 contains a combination of intermediate-acting insulin with regular insulin

Other type 1 diabetes medications

An amylinomimetic drug called pramlintide can be used as an injection before meals. It works as follows:

  • Slows down the time it takes your stomach to empty
  • Reduces the release of sugar after meals
  • May reduce your appetite and help you lose weight

Symlin Pen is the brand available.

Type 2 diabetes medications

Biguanides

This class of drug is one of the earliest medications for diabetes. Biguanides such as metformin are used regularly as a first-line treatment for type 2 diabetes and are the most common medication used for diabetics. It is unsuitable for anyone with liver, kidney, or heart problems.

How do Biguanides work?

  • Slows down the absorption of glucose from your intestines
  • Reduces how much sugar your liver makes
  • Helps to reduce your insulin resistance

Advantages of Biguanides

  • No weight gain side effects
  • Very effective

The most common side effects caused by Biguanides include:

  • Decrease in vitamin B12 absorption
  • Bloating
  • Diarrhea
  • Nausea
  • Weight loss

Common Biguanides brands:

Meglitinides

How do Metiglinides work?

  • Stimulates the release of insulin from your pancreas

Advantages of Metiglinides:

  • Works quickly
  • Allows you to be flexible with your dose

The most common side effects caused by Meglitinides include:

Popular Meglitinide brands include:

  • Prandin (repaglinide)
  • Prandimet (repaglinide-metformin)
  • Starlix (nateglinide)

Sulfonylureas

How do Sulfonylureas work?

  • Stimulates the cells of your pancreas to make and release more insulin

Advantages of Sulfonylureas:

The most common side effects caused by Sulfonylureas:

  • Diarrhea
  • Feeling sick
  • Skin rashes
  • Itching
  • Weight gain
  • Low blood sugar (hypoglycemia)

As with insulin, Sulfonylureas can be classed as short, medium, or long-acting depending on how fast they work.

  • Short-acting – tolbutamide (Rastinon)
  • Medium-acting – glimepiride (Amaryl)
  • Long-acting – chloropropamide (Diabinese)

Glinides

How do Glinides work?

  • Stimulates your pancreas to produce more insulin

Advantages of Glinides:

  • Fast-acting

Possible side effects:

Common Glinides:

  • Prandin – repaglinide
  • Starlix -nateglinide

Thiazolidinediones

How do Thiazolidinediones work?

  • Causes changes in your muscle and fat cells where insulin resistance occurs

Advantages of Thiazolidinediones:

  • Does not cause low blood sugar
  • May protect beta cells in your pancreas

The most common side effects caused by Thiazolidinediones include:

  • Headaches
  • An increase in upper respiratory tract infections (like colds and throat infections)
  • Fluid build-up that causes swelling in your hands, feet, and ankles
  • Weight gain

Popular Thiazolidinediones include:

Alpha-glucosidase inhibitors

How do Alpha-glucosidase inhibitors work?

  • Interrupts the breakdown of carbohydrates into sugar in your gut, so it stops your body from absorbing glucose

Advantages of Alpha-glucosidase inhibitors:

  • Especially useful if you have type 2 diabetes where your blood sugar tends to be most out of control after eating

The most common side effects caused by Alpha-glucosidase inhibitors include:

  • Bloating
  • Gas
  • Diarrhea
  • Abdominal cramps
  • Stomach pain

Common brands include:

  • Glyset – miglitol
  • Precose – acarbose

Dopamine agonists

How do Dopamine agonists work?

  • It’s not known exactly how this drug works to treat type 2 diabetes. It may affect rhythms in your body and prevent insulin resistance

Advantages of Dopamine agonist:

  • Does not cause low blood sugar or weight gain

The most common side effects caused by Dopamine agonists include:

  • Heartburn
  • Feeling sick
  • Vomiting
  • Loss of appetite
  • Drowsiness
  • Dizziness

Common brands include:

Dipeptidyl peptidase-4 (DPP-4) inhibitors (Gliptins)

How do Dipeptidyl peptidase-4 work?

  • Blocks the production of an enzyme called Dipeptidyl peptidase-4 allowing your body to release more insulin

Advantages of Dipeptidyl peptidase-4:

  • Does not cause low blood sugar or weight gain
  • Possible beneficial effects on cholesterol levels

The most common side effects caused by DPP-4 inhibitors include:

  • Upper respiratory infection
  • Nausea
  • Headaches
  • Mild indigestion

Common brands:

  • Januvia – sitagliptin
  • Onglyza – saxagliptin
  • Galvus – vildagliptin

Glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) / Incretin memetics

How does it work?

  • An injected medicine that helps prevent your blood sugar from rising after eating by slowing the rate of digestion and the release of insulin

Advantages:

  • May suppress hunger
  • Modest weight loss

Side effects:

  • Nausea
  • Headache
  • Diarrhea
  • Low blood sugar

Common brands:

Amylin mimetics

How do Amylin mimetics work?

  • Helps control your glucose levels
  • Slows the movement of food through your stomach
  • Used with insulin injections

Advantages of Amylin mimetics:

  • May suppress hunger
  • It may help with some weight loss

Possible side effects:

  • Hypoglycemia (low blood sugar levels)
  • Nausea
  • Vomiting

Common brands:

  • Symlin – pramlintide

Sodium-glucose transporter (SGLT) 2 inhibitors

How do SGLT2 inhibitors work?

  • Sodium-glucose transporter SGLT2 inhibitors work by preventing your kidneys from holding on to glucose. Instead, your body gets rid of the glucose through your urine

Advantages of SGLT2 inhibitors:

  • These drugs may possibly reduce your risk of cardiovascular disease, heart failure, or chronic kidney disease. The ADA recommends SGLT2 inhibitors as a possible treatment option

The most common side effects caused by SGLT2 inhibitors include:

  • Nausea
  • Constipation
  • Dehydration
  • Risk of genital yeast infections
  • Risk of urinary tract infections
  • Low blood sugar (hypoglycemia)

Popular SGLT2 inhibitor brands include:

Bile acid sequestrants

How do Bile sequestrants work?

  • It is thought to lower glucose levels in your bloodstream by attaching itself to bile acids in your intestines
  • Researchers are still working to understand how exactly it works

Advantages Bile sequestrants:

  • Safer if you have liver problems

Side effects:

  • Gas
  • Constipation
  • Indigestion

Common brands:

  • Welchol – colesevelam

Combination Oral Pills

Over time as a type 2 diabetic, your medication will change as your diabetes progresses. You may require multiple medications to keep your blood sugar level stable and within the safe range. Combination oral pills combine the effects of two medications in one drug.

Examples of combination medications for type 2 diabetes:

  • Glucovance – metformin and glyburide
  • Metaglip – metformin and glipizide
  • Avandaryl – rosiglitazone and glimepiride
  • ACTOplus Met – pioglitazone and metformin
  • Avandamet – rosiglitazone and metformin
  • Duetact – pioglitazone and glimepiride

Other diabetes medications

Diabetes is much more than just blood glucose levels e.g type 2 diabetics have a higher risk of heart attacks and strokes, therefore medications to control blood pressure and cholesterol are very useful.

Here are some of the most widely used medications:

  • ACE inhibitors – they act on your kidneys to treat high blood pressure
  • AIIRA’s – reduces high blood pressure
  • Aspirin – reduces the stickiness of your blood, making you less prone to heart attacks and stroke
  • Statins – they lower your LDL cholesterol (considered as the bad cholesterol) and raise your HDL (considered as good cholesterol) helping to protect you against heart disease

Diabetes medication FAQs

What is the latest drug for diabetes?

The three latest drugs for diabetes are:

  • Rybelsus (semaglutide) is the first oral medication in the glucagon-like peptide-1 receptor agonists class of drugs, approved in 2019 for type 2 diabetics. It helps your pancreas to release the correct amount of insulin when your blood sugar levels are high
  • Baqsimi (glucagon) is the first glucagon therapy in a nasal powder that can treat severe hypoglycemia, without an injection
  • Victoza (liraglutide) is the first non-insulin drug to treat type 2 diabetes in children since metformin

Diabetes drugs being developed:

  • Imeglimin, the first in a new class of anti-diabetic medication that maintains beta-cell function in your pancreas and increases insulin production
  • Dasiglucagon HypoPal – a rescue pen for severe hypoglycemia (low blood sugar levels)

What is the safest drug for diabetes?

There is no evidence to suggest that one diabetes drug is safer than another.

What is the cheapest diabetic medicine?

Metformin.

Why are doctors not prescribing metformin anymore?

In June 2020, metformin extended-release tablets were recalled because of higher levels of NDNA (n-nitrosodimethylamine) than acceptable by the FDA. The FDA advises that you should continue to take extended-release metformin until your doctor or pharmacist gives you an alternative.

Should diabetics take aspirin daily?

Aspirin has proven to be an effective treatment for people with diabetes. The drug works on the platelets in your blood, reducing the risk of cardiovascular events. Since people with diabetes are two to four times more likely to develop cardiovascular problems, aspirin is commonly prescribed daily. Since 1997 the American Diabetes Association has recommended aspirin for diabetics. However, aspirin use in diabetics under 30 years of age has not been studied, and taking aspirin by diabetics under 21 years of age is not recommended.

Is there an insulin pill for diabetes?

Currently, the answer is no but there are drugs that are in early development to offer patients an alternative to injecting insulin. Several pharmaceutical companies are racing to be the first to launch insulin pills.

Do I need insulin with type 2 diabetes?

Type 2 diabetes can be treated in the first instance with diet and lifestyle changes, followed by oral medication if needed. However, most type 2 diabetics will eventually need to take insulin by injection. It is important to remember that type 2 diabetes is a progressive disease and medication changes will occur over the years.

Can you reverse diabetes?

Diabetes is a lifelong condition that can be significantly improved but not cured. You can reverse diabetes symptoms for some time, but there is always the chance they could return. Meal planning, healthy eating, exercising, and maintaining a healthy weight are essential to keep diabetes symptoms away.  “Reverse” does not mean a forever cure. Diabetes is an ongoing disease.

Understanding blood sugar

As a person with diabetes, you know that your blood sugar level rises but you need to understand why that is. This is where insulin resistance comes in. Most people who develop type 2 diabetes have insulin resistance for years before they are diagnosed with diabetes itself. When you have insulin resistance your body needs to produce more insulin than other people to keep your blood sugar within the normal range. Your body reacts by overproducing insulin from the beta cells in your pancreas. This causes your body to eventually burn out with the extra demand placed on it. Eventually, your pancreas becomes less efficient to tackle insulin resistance and results in Type 2 diabetes.

If you have Type 1 diabetes you can not produce any insulin at all or very little.

Reversing diabetes with food

A diet that helps you manage or reverse your diabetes should be centered around:

  • Healthy natural fats such as nuts, seeds, avocados, salmon, flaxseeds, and extra virgin olive oil
  • Fewer calories, particularly from carbohydrates
  • Lean protein such as chicken and turkey
  • Minimal alcohol
  • Minimal sweets/sugar

Ketogenic diets are sometimes useful to reverse symptoms of diabetes. Our other guides can teach you more about keto diets as well as alcohol consumption for diabetics. At NiceRx we want you to understand your condition and live the best life you can.

A calorie-controlled diet

Studies have found that nearly half the people who took part in a calorie-controlled diet reversed their diabetes. As a result, their blood glucose remained near the normal range for at least 6 months to a year. People who lost weight had lower levels of fat in their liver and pancreas, and for some of them that helped the beta cells in their pancreas that release insulin and control blood sugar to start working again.

In theory, losing weight is easy. Eat fewer calories than you use up, you lose weight. Losing weight is difficult for many reasons, but frustration by slow weight loss is probably the main reason. One way to keep yourself motivated is to focus your mind on the end goal – reversing your diabetes.

Exercise

There is a close link between a lack of physical activity and diabetes. At this point, you have probably already realized that successfully maintaining your weight loss requires a willingness to make exercise a regular part of your life. The best way to introduce exercise into your life is to go slow and steady. You need to select an activity that you enjoy and will continue to perform.  If you are in good shape, moderate exercise could be a light jog. If you are out of shape, moderate exercise for you may be slow walking. Your choice of activity must take into account your physical condition. Here are some exercise ideas as a starting point:

  • Walking – the most sustainable exercise as it requires no equipment apart from comfortable shoes
  • Dancing – taking a dance class at a local community center or gym
  • Swimming – low impact as it does not put pressure on your joints
  • Yoga

A study carried out in 2003 provides evidence for the benefits of walking. It showed diabetic patients who walked at least 2 hours a week had a 40% lower death rate than inactive diabetics.

Tips to start walking:

  • Find a walking buddy to make it fun
  • Take a daily lunchtime walk
  • Use the stairs instead of a lift
  • Set a daily step goal

Movement of any type can improve heart function. In addition, it helps control body fat which is especially good for diabetic patients. Talk to your doctor before making a plan new exercise to make sure you come up with one that is suitable for you.

Will reversing diabetes with exercise work?

A study carried out in the UK called DiRECT (Diabetes Remission Clinical Trial) shows some people can put their diabetes into remission. The people in the study followed a low-calorie, diet-based, weight management program working closely with their doctor. After a year, 46% achieved remission to a non-diabetic state and off antidiabetic drugs.

There is a good amount of evidence from a number of scientific studies that show that low carbohydrate diets are an effective option for treating diabetes.

Other measures to reverse diabetes

Bariatric surgery

Bariatric surgery is thought to be the most extreme way to reverse diabetes. You may get to this point if you have found it impossible to lose weight or are extremely overweight. Bariatric surgery changes how much food your body can take in by adjusting your stomach and digestive system. After surgery, your stomach will be smaller, will feel full with less food, and fewer calories are taken in. Bariatric surgery is recommended for patients with type 2 diabetes and a BMI (Body Mass Index) of 40 or over by The American Diabetes Association. This BMI value will differ depending on your ethnic group and if you suffer from other health problems. You must make permanent healthy changes to your diet and lifestyle for the long-term success of bariatric surgery.

Fasting

Fasting to reverse diabetes is simply going without food for a set amount of time. You can choose to eat between a set window of the day. For instance, between 12-8 pm and no food for the rest of the day. You could also fast a full 24 hours without eating followed by 24 hours of eating as usual. There are many different methods of fasting. A very small study in 2018 found that going without food for a set amount of time can help reverse type 2 diabetes. Still, more research is needed.

Reversing diabetes FAQs

How long does it take to reverse Type 2 diabetes?

As soon as possible after you are diagnosed start a weight loss plan. Success in reversing diabetes is seen particularly in those people who have had diabetes for a shorter amount of time.

Which medications are used to treat Type 2 diabetes?

Some of the most popular drugs that are used to treat Type 2 diabetes include:

Can walking cure diabetes?

Walking can not cure diabetes but can help keep your weight down. As a result, your diabetes symptoms and your quality of life will be improved.

Is fasting good for diabetes?

A study looked at three people with type 2 diabetes who used insulin and fasted three times a week. Within a month, insulin was no longer needed by these people. The sample size is far too small to make any strong conclusions. It is important to remember that fasting can reduce your calories and improve your diabetes. Fasting causes changes in your blood sugar levels. As a result, you need to work closely with your healthcare professional to find what works for you.

How much water should a diabetic drink?

Drinking water is important for everyone, particularly if you are diabetic. Water has many jobs in the body. One of them is to flush waste products out of your body. When you don’t drink enough water, the glucose in your bloodstream becomes concentrated leading to higher blood sugar levels. Even slight dehydration can affect you if you are diabetic. The U.S Dietary guidelines 2020-2025 do not recommend a specific daily water intake but do recommend plain water over added sugar varieties. Water intake varies greatly according to age, activity, and various individual factors. As a guide The Institute of Medicine suggests men drink about 3 liters of water a day and women 2.2 liters a day.

How much weight do I need to lose to reverse Type 2 diabetes?

There is no set amount of weight that guarantees the reversal of type 2 diabetes. Every person is unique so it is very specific to you. Weight loss and diabetes improvement go hand in hand as shown in many studies.

What are normal blood glucose levels?

Normal blood glucose levels for adults without diabetes are 90 to 110 mg/dL. Learn more about the symptoms of low and high blood sugar.

The goal of diabetes treatment is to keep your blood sugar level (also called blood glucose level) in your bloodstream as close as possible to normal. The closer you get to reaching this, the better you will feel, especially in the long term. Blood sugar tests will allow you to check that you are in your target range and your diabetes educator to know how well your diabetes care is managed. In time, as you check your levels, you will get to know which foods increase your blood sugar levels and how your medication and exercise affect your levels day to day. Keeping a log of your symptoms, the food you have eaten, activity, and stress levels will help manage your blood sugar levels. Other medical conditions you may have will also influence your blood sugar control. This information is valuable as it lets you know what works for you and what changes your healthcare provider needs to make to your treatment plan.

What are normal blood sugar levels?

The blood glucose level is the amount of glucose in the blood. According to the American Diabetes Association (ADA), the normal blood sugar levels for a person without diabetes are:

  • Fasting blood sugar level – under 100mg/dL (in the morning before eating)
  • 1 hour after eating 90-130mg/dL
  • 2 hours after eating 90-110mg/dL
  • 5 or more hours after eating 70-90mg/dL

Blood sugar level charts for people with diabetes

The American Diabetes Association suggests the following targets for most non-pregnant adults with diabetes:

Target blood sugar levels for pre-diabetics and diabetic adults

Type of patient (adult)FastingA1c (measured over a 3-month period)Oral glucose test (2 hour)
Prediabetes100mg/dL - 125mg/dL5.7%-6.4%140mg-199mg/dL
Diabetes126mg/dL or higher6.5% or higher200mg/dL

Children, teens, and adolescents with diabetes should aim to keep within these ranges:

Adolescent blood sugar level chart

AgeFastingBefore mealBefore exerciseBedtimeA1c (measured over 3-month period)
6-12 years old8-180mg/dL90-180mg/dLat least 150mg/dL100-180mg/dL8.0%
13-19 years old70-150mg/dL90-130mg/dLat least 150mg/dL90-150mg/dL7.5%

The A1c or HbA1c (the glucose-hemoglobin part of the red blood cell) test looks at how good your blood glucose control has been over a period of 3 months. These values are a guide. Your doctor will provide you with a personal management plan to determine your normal range.

Symptoms of low blood sugar levels

Low blood sugar is also as known as hypoglycemia or a hypoglycemic episode. Severe hypoglycemia is dangerous and needs to be treated right away. The brain works entirely on glucose for normal functioning. If levels drop too low, it starts to work less well.

Some symptoms of hypoglycemia:

  • Sweating, or cold and clammy
  • Dizziness
  • Blurred vision
  • Shakiness
  • Drowsy
  • Confusion
  • Irritable, upset, or angry
  • Tingling lips
  • Lightheadedness
  • Fast heart rate
  • Hunger

These symptoms cause you to lose the ability to think clearly and you may appear to be behaving oddly. The low blood sugar symptoms you get and how severe they are will vary from person to person. Recurrent episodes of hypoglycemia can lead to hypoglycemic unawareness, or the decreased ability to recognize the signs of hypoglycemia. If you have hypoglycemia unawareness or have low blood glucose often, a continuous glucose monitor (CGM) may be a good option.

What causes low blood sugar?

Low blood sugar episodes can be caused by many different reasons:

  • Irregular eating habits – eating later than you expected or planned or skipping meals
  • Drinking alcohol – alcohol can block your liver’s ability to release glucose
  • Exercise –  we hope you do exercise! Keep in mind exercise lowers blood sugar levels. Insulin dose or food intake adjustments are needed to match your physical activity
  • Medication side effects – diabetes medicines such as insulin and sulfonylureas carry a much higher risk of low blood sugar than all the others. The antimalarial drug Qualaquin (quinine) is another example
  • Other medical conditions – such as problems with your hormone levels, pancreas, liver, kidneys, adrenal glands, or heart can cause low blood sugar levels

What to do if your blood sugar gets too low

If your blood sugar level drops lower than 70 mg/dL, do one of the following; chew 4 glucose tablets, drink 4 ounces of fruit juice or regular soda (not diet), or chew 4 pieces of hard candy. Wait 15 minutes after taking one of these treatments. Measure your blood sugar again. Repeat the process until your blood sugar level reaches 70 mg/dL or above, then eat a snack if your next meal is 1 hour or more away.

You must remember that wherever you are, you always carry a readily available carbohydrate such as hard candy or glucose gel. This is most important if you are a driver or exercise regularly. Injectable glucagon is the best way to treat severe low blood sugar. A glucagon kit containing a glucagon injection is available by prescription. Let family members and co-workers know where you keep the glucagon kit and make sure they’ve been trained in how to use it.

Symptoms of high blood sugar levels

High blood sugar is also known as hyperglycemia. Generally, there are two reasons for this happening. Either the body does not have enough insulin or it cannot use insulin properly. The following symptoms occur:

  • Headaches
  • Blurred vision
  • Excessive thirst
  • Dry mouth
  • Frequent urination
  • Tiredness
  • Weight loss
  • Fruity smell to your breath
  • Thrush and bladder infections

High sugar levels slowly erode the ability of cells in your pancreas to make insulin. Frequent and prolonged high blood sugar levels can lead to diabetic ketoacidosis (DKA). As the name suggests, your blood becomes acidic due to the presence of high levels of ketones. The smell of acetone on the breath is one of the classic ways your doctor can make a diagnosis.

Symptoms of ketoacidosis:

  • Extreme tiredness and drowsiness
  • Nausea and vomiting
  • Weakness
  • Rapid breathing
  • Confusion

Diabetic ketoacidosis is a medical emergency that needs to be treated immediately.

What causes high blood sugar?

High blood sugar can happen for many different reasons, including being unwell, eating more than planned, not producing enough insulin in your body, unplanned physical activity, and stress. Untreated hyperglycemia can lead to serious health problems.

What to do if your blood sugar gets too high?

Check your blood sugar level. Is it above 180mg/dL or your own individual target level? If the answer is yes, drink a large glass of water and take a brisk walk. Serious complications can happen if your blood levels are high e.g. more than 3 times in 2 weeks. Always inform your healthcare team of high sugar levels.

Monitoring your blood sugar levels

As a diabetic, monitoring your blood sugar level is unquestionably the best way to know what is going on inside you. Keeping your blood glucose under tight control undoubtedly reduces the chance of developing complications. Using a blood glucose meter for glucose monitoring is an essential tool in your diabetes management. How often you check your blood sugar depends on the type of diabetes you have.

Individual blood glucose test strips are great for knowing immediately how your diabetes is controlled. It is equally important to know how you are doing over weeks and months. The A1c test gives us this information as it looks at how good your blood glucose control has been over a period of 3 months. An A1c value of 7% is the general goal for diabetic adults but can differ depending on age and other factors. If treatment is working this A1c test should show improvement.

The A1c test is a great test for a diabetic woman who wants to get pregnant. You can find out if your blood glucose has been well controlled before conceiving. If it has not, you can wait until you have good control. In this way, you reduce the possibilities of complications with your baby.

When to check your blood sugar levels

Type 1 diabetes, adult: Check at least twice daily, up to 10 times a day. You should perform tests before breakfast, at fasting, before meals, sometimes 2 hours after meals, before and after physical activity, and at bedtime.

Type 1 diabetes, child: Check at least four times daily. You should perform tests before meals and at bedtime. Tests may also be required 1–2 hours after meals, before and after exercise, and overnight.

Type 2 diabetes, people using insulin or other management medications: The recommended frequency of testing varies depending on insulin dosage and the use of any additional medications.

Managing your blood sugar

  • Dietary changes
  • Increase exercise
  • Keep a healthy weight
  • Drink alcohol moderately
  • Keep a logbook of blood sugar readings
  • Take your diabetes medication regularly
  • Becoming totally aware of your own symptoms for low/high blood glucose

Blood sugar levels FAQs

How to reduce blood sugar levels immediately?

If it is an emergency and you need to reduce blood sugar levels immediately, use insulin. An extra dose of insulin can be taken if you have either type 1 or type 2 diabetes. The amount depends on the situation and your doctor’s recommendation. It is important you know when to seek medical attention in an emergency.

What is the average blood sugar level?

Average blood sugar levels differ based on age, how long you have had diabetes, current medication, and other medical illnesses. Your healthcare team will take these into consideration to work out your ideal levels.

Which medications are commonly used to lower blood sugar levels?

Some of the most popular diabetes medications that are used to lower blood sugar levels include:

What medications can raise blood sugar levels?

Many types of medications and some OTC (over-the-counter) medications raise blood sugar levels, but this does not mean they can not be taken if they are needed. You must work with your doctor on the correct way to use them. Some prescription medicines that increase blood sugar levels are steroids, birth control pills, statins, drugs that treat mental health issues, medication for acne, and high doses of asthma medicines. Some OTC medicines that increase blood sugar levels include decongestants, cough syrups, and supplements.

Common medications that cause an increase in blood sugar levels are:

  • Beta-blockers e.g. atenolol
  • Diuretics
  • Corticosteroids e.g. prednisone for rheumatoid arthritis treatment
  • Over the counter supplements e.g. niacin
  • Antidepressants e.g. selective serotonin reuptake inhibitor drugs like citalopram

Can stress cause high blood sugar levels in non-diabetics?

When you are stressed the hormone cortisol is released. Cortisol blocks the effects of insulin in your body. This means sugar is not moved from the blood into the cells and can cause high blood sugar levels in non-diabetics. If cortisol is released too often or its effects last too long it raises insulin levels and can result in insulin resistance and type 2 diabetes.

How to reduce blood sugar levels during pregnancy?

Maintaining blood glucose levels for pregnant women can be tricky. The goal is to keep blood glucose levels stable whether you have diabetes before pregnancy or have gestational diabetes as a result of pregnancy. You need to watch your blood sugar levels more closely during pregnancy because if your levels get too high they can affect your baby. You will be given a blood glucose monitor.

A screening test for gestational diabetes is usually done in the second trimester between 24 and 28 weeks of pregnancy. If your levels get too low you will experience lightheadedness, confusion, and fainting. This is why it is so important for you to be in the best possible shape before you even try to conceive.

The five main ways to reduce your blood sugar levels during pregnancy are:

  • Eat a balanced diet with healthy food, more non-starchy vegetables, and whole grains like brown rice
  • Regular exercise (moderate)
  • Keep your weight down – obesity (body mass index (BMI) > 24) increases your risk of gestational diabetes
  • Test your blood glucose levels regularly
  • Take your medication e.g. insulin injections

High risk factors, such as high blood pressure, a history of polycystic ovary syndrome (PCOS) or heart disease, and race have to be taken into consideration (Hispanic and Pacific Islander women are at increased risk) You also need to work more closely with your doctor during this time to have a healthy pregnancy and to protect your baby’s health from birth defects. Checkups and follow up appointments are important to attend.

What is pre-diabetes?

Prediabetes is when your blood sugar is high, but the blood test results are not high enough to be classified as diabetes. An oral glucose tolerance test is used to diagnose prediabetes with a blood sample.

Your healthcare professional will discuss your risk factors of diabetes such as your family history, other health conditions, and your current lifestyle. After gathering all this information advice will be given on how to bring your blood sugar levels into a healthy range.

Lifestyle changes including eating a healthy diet and knowledge of low GI foods are very important when you have been diagnosed as borderline diabetic. A dietitian can put together a pre-diabetes diet and meal plan with you looking at:

  • Calorie intake
  • Low carb intake
  • Low glycemic index foods (GI foods) e.g. lentils
  • Low-fat alternatives
  • Healthy fats e.g. olive oil
  • Omega-3 fatty acids e.g. salmon

Read our blog on Top 20 best snacks for diabetics for ideas on healthy choices.

Your care team will also discuss ways to increase your physical activity, and how to keep your cholesterol and blood pressure under control to reduce your risk of diabetes. Metformin is often recommended for individuals with prediabetes if healthy eating and lifestyle changes are not enough.

What are the complications of high blood sugar levels?

Diabetes complications can occur if your diabetes is not treated correctly, issues it can cause are:

  • Heart disease leading to a heart attack
  • Kidney disease
  • Vision loss e.g. cataracts, glaucoma
  • Foot and skin problems e.g. dry skin, loss of elasticity of the skin, or ulcers on the feet
  • Blood vessel damage
  • Nerve damage

Some complications of diabetes can lead to life-threatening problems if they are not picked up and treated on time. Read our blog on the complications of diabetes for more detailed information.

Which foods raise blood sugar levels?

There are several foods that a person with diabetes should either avoid or eat only in moderation.

The following can cause blood sugar spikes:

  • Sugary drinks, such as soda, juices, and sports drinks
  • Food made from refined grains e.g. white rice, white bread, white pasta, crackers
  • Foods containing trans fats e.g. margarine, peanut butter, spreads, creamers, and frozen dinners
  • Food with added sugar e.g. yogurts, breakfast cereals, dried fruit
  • Honey and maple syrup
  • Flavored, sugary coffee drinks
  • French fries

Read our blog on what foods to avoid with diabetes for more information.

US mental health index

Which States are best-equipped to deal with mental illness?

Mental illnesses are a collection of disorders with a range of symptoms that sadly impact the lives of millions of Americans every year. In fact, according to John Hopkins Medicine, the number of adults who suffer from a diagnosable mental condition in any given year is estimated to be as high as one in four.

Consequently, there could be over 52 million Americans currently suffering from a mental disorder, ergo it would be extremely beneficial to live in a state that is well-equipped to cater for sufferers of mental health conditions.

To discover which states are the best for dealing with mental health issues, we took into account six different factors to calculate an overall score out of ten for each of the 50 states (as well as the District of Columbia).

These factors are: the percentage of the adult population experiencing any mental illness (AMI), the percentage of the adult population with serious thoughts of suicide, the percentage of adults suffering from mental illness who did not receive treatment, the percentage of the youth population to experience at least one major depressive episode, the percentage of the depressed youths who did not receive treatment, and the number of people in the population per mental health professional.

The best states for dealing with mental illness

Best states

1: District of Columbia – 7.52/10

Although it is not technically a state, the US capital district is home to almost 700,000 people, and they are all in a good position when it comes to their mental health compared with other areas of the country. Overall D.C. had the highest ranking anywhere in the country and scored 7.52/10, this is helped by being the state with the lowest percentage of young people experiencing a depressive episode (10.49%), additionally it scores highly in every other category.

2: Connecticut – 7.41/10

The northeast state of Connecticut comes in second place in the rankings with an overall score of 7.41/10, although Connecticut was not the top state in any one category it was extremely consistent across the board as it scored in the top twenty for four of the six categories. Mental health awareness amongst young people seems to be prevalent as only 43.9% of youths experiencing depression did not get treated, far lower than the national average of 57.78%.

3: New Jersey – 7.39/10

The third best state for dealing with mental illness is New Jersey which achieved an overall score of 7.39/10. New Jersey has the lowest rates of mental illness in both adults and youths anywhere in the country, with only 16.14% of adults suffering from any mental illness. However, those that are mentally ill in New Jersey are not that likely to get medical attention as 60% of adults did not receive treatment (this makes them the tenth worst state in this regard), this may be due to the high number of people per mental health professional. There are 500 New Jerseyites per mental health professional, this is 27 more than the national average.

 

The worst states for dealing with mental illness

Worst states

1: District of Columbia – 7.52/10 

Although it is not technically a state, the US capital district is home to almost 700,000 people, and they are all in a good position when it comes to their mental health compared with other areas of the country. Overall D.C. had the highest ranking anywhere in the country and scored 7.52/10, this is helped by being the state with the lowest percentage of young people experiencing a depressive episode (10.49%), additionally it scores highly in every other category.

2: Connecticut – 7.41/10

The northeast state of Connecticut comes in second place in the rankings with an overall score of 7.41/10, although Connecticut was not the top state in any one category it was extremely consistent across the board as it scored in the top twenty for four of the six categories. Mental health awareness amongst young people seems to be prevalent as only 43.9% of youths experiencing depression did not get treated, far lower than the national average of 57.78%.

3: New Jersey – 7.39/10

The third best state for dealing with mental illness is New Jersey which achieved an overall score of 7.39/10. New Jersey has the lowest rates of mental illness in both adults and youths anywhere in the country, with only 16.14% of adults suffering from any mental illness. However, those that are mentally ill in New Jersey are not that likely to get medical attention as 60% of adults did not receive treatment (this makes them the tenth worst state in this regard), this may be due to the high number of people per mental health professional. There are 500 New Jerseyites per mental health professional, this is 27 more than the national average.

 

The worst states for dealing with mental illness

Top worst

Adults Experiencing Mental Health Issues:

Best State: New Jersey – 16.14%

Worst State: Utah – 25.25%

 

Adults with serious thought of suicide:

Best State: New Jersey – 3.41%

Worst State: Utah – 5.99%

 

Mentally ill adults who did not receive treatment:

Best State: Vermont – 42.8%

Worst State: Hawaii – 65.8%

 

Young people with at least one major depressive episode:

Best State: District of Columbia – 10.49%

Worst State: Oregon – 16.34%

 

Young people with depressive episodes not receiving treatment:

Best state: Rhode Island: 39.5%

Worst State: North Carolina: 74.3%

 

Number of people in the population per mental health professional:

Best State: Massachusetts: 180 people per professional

Worst State: Alabama: 1,100 people per professional

 

State table

 

 

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Methodology

 

  • All data was collected from: https://mhanational.org/issues/2020/mental-health-america-adult-data
  • We chose six categories that we felt could give the best indication of the prevalence of mental health issues within each state, and the level of care available and utilized.
  • To create an overall score for each state we used a weighted index table to rank each factor out of ten and then create an overall average score.

 

The global prescription index

Like many other countries across the globe, Americans have to pay for prescription drugs, but how does the cost in the US compare to those around the world?

We would analyze OECD data to discover how much the cost of prescription medication has increased in the US over the past 10 years.

We will create an index that analyses and compares the cost of prescription drugs in the US to countries around the world.

A concept that creates a real talking point and allows us to draw global comparisons while maintaining relevancy and a voice within the health space.

Where in the world pays the most for their medication?

People often say that nothing is more important than your health, and they’re not wrong. When you’re unwell it can be difficult to enjoy life, and all that occupies your mind is getting better again. However, being unwell or having health conditions can not only be uncomfortable and problematic but can also put a big strain on your finances.

Whether you’re taking budesonide for your asthma or lisdexamfetamine for ADHD, the costs of your prescriptions can quickly add up. This has led many people to search for affordable medications online or even cross borders to purchase them at better prices.

With people going to such lengths to be able to afford their prescriptions, we wanted to find out just how much the average American spends on medication each year, and how this compares to people in other countries.

We’ve put together the Global Prescription Index to reveal which countries spend the most on their prescriptions, and how prices have changed over the years.

US spending on medication per year

The table below shows how much is spent on prescriptions per capita in the United States each year, from 2000 up to the most recent data from 2018. You can also see the year-on-year percent change in prescription spending.

US spending on medication per year

As of 2018, the average American spends $1,228.66 every year just on medication and pharmaceuticals. This is a difference of $687.86 since 2000, representing a 127.19% increase in that time.

This is a huge amount to be spending each year, especially when money is tight or if you’re trying to save enough for a deposit. For those on lower incomes, it poses a serious risk of falling into debt, especially if their condition begins to worsen.

The countries that spend the most on prescription medication

Below you can see the top ten countries that spent the most money on medication in 2018.

The countries that spend the most on prescription medication

 

1. The United States                                         $1,228.66

The USA is the country that spent the most on medication per capita in 2018, spending over $330 more per capita than any other country. This is a result of the rising cost of many prescription medications, leading to financial difficulties for many Americans, regardless of their insurance status.

2. Switzerland                                                    $893.88

Switzerland has the second-highest spending on prescriptions, having spent $893.88 per capita on medication in 2018. Switzerland has a very highly regarded healthcare system that requires all residents to have private health insurance by law. However, with average salaries in the country standing at around 124,000CHF (Approx. $134,410), this is relatively much more affordable than it might seem at first glance.

3. Germany                                                        $883.64

In third place is Germany, with a prescription medication spend per capita of $883.64, which is only a fraction less than is spent in Switzerland. This level of spending represents a considerably more attractive scenario than in the USA, as the ratio of cost is about $7 spent in the States for every $5 spent in Germany.

It’s also worth noting that Canada places fourth, spending $865.19 per capita on medication. Even with spending in the country being the fourth highest, Americans will still make the trip across the border to take advantage of the relatively lower prices. This highlights just how expensive medication in the US has become.

The countries where prescription spending has increased the most

Here we’ll look at the countries that experienced the greatest increase in spending on medication in the five years from 2013 to 2018.

The countries where prescription spending has increased the most

 

1. Costa Rica                                                                 70.56%

Costa Rica experienced by far the greatest increase in spending per capita on medication between 2013 and 2018, reaching 70.56% higher levels in the country. As a territory of the United States, it might be playing some catch-up, as actual levels of spending were only $275.04 per capita in 2018. That’s almost $1000 less than in the USA!

2. Latvia                                                                         52.13%

Latvia experienced the second-highest increase in spending on prescriptions and medication, with spending levels increasing by 52.13% in just five years. This brought the spending per capita on medication in the country to $491.72, which is still less than half the amount spent in the States.

3. Bulgaria                                                                     44.44%

In third place is Bulgaria, where the amount spent per capita on pharmaceuticals rose by 44.44% to $625.03. Despite being barely more than half the amount spent in the USA, this is actually relatively expensive as the average salary in Bulgaria is around 39,600BGN (Approx. $24,010). This means that medication costs could take up around 2.6% of your income in Bulgaria.

Meanwhile, the United States placed ninth with an increase of 23.56% over the five-year period. This is a considerable increase considering spending per capita in the US was already by far the highest in 2013 at $994.36 and has allowed the gap between the US and the next highest spending country to increase from $295.12 in 2013 to $334.79 in 2021.

Pharmaceutical spending by country

Here’s our full list of the 35 countries for which complete data was available. All countries are ranked according to the amount spent on medication per capita in 2018.

Pharmaceutical spending by country

Changes in pharmaceutical spending per capita by country

Below you can find the % changes in spending per capita on medication for each of the 35 countries, ranked from the highest increase to the greatest decrease.

Changes in pharmaceutical spending per capita per country

Methodology

We wanted to find out how much people spend on medication in the United States, and compare it with other countries around the world. To do this, we used OECD data on the amount spent on pharmaceuticals in 35 countries from 2013 up to 2018. The majority of countries did not have data for more recent years, so the most recent year with complete data was chosen, along with the previous 5 years in order to show how rates of spending had changed.

The data was ordered from highest 2018 spend to lowest and ranked accordingly. This allowed us to draw a direct comparison between the rate of spending in the US and that of other countries.

Next, we calculated the change in spending between 2013 and 2018 and presented it as a percentage figure. Again, we ranked the countries from the highest increase to the greatest decrease. This gave us insight into how spending on medication is changing from country to country.

If you’re struggling to pay for your medication, NiceRx may be able to assist. We provide access to affordable brand name medications, including JanuviaTrulicity, Dexilant, Amitiza and more.

Uninsured America

Where in the US do most people have no health insurance?

There’s nothing more important than our health. When we’re unwell our quality of life drastically decreases, we struggle to enjoy life and find it more difficult to work and earn a living. However, there’s still a large number of Americans who have no health insurance, and many people avoid seeing the doctor because they don’t have the money to spare for expensive medical bills.

Due to the high cost of medication and medical appointments, many people are putting themselves at risk by not seeking proper medical advice, and it’s fairly commonplace for Americans to drive hundreds of miles to Canada to find their medication at an affordable price. Thankfully, you can now buy most medications online at increasingly affordable prices, preventing you from overpaying on anything from insulin to lisdexamfetamine.

But, with so many Americans with no health cover, this is clearly still a serious nationwide issue. We wanted to find out where in the country the most people are uninsured. We’ve looked at data for every state and state capital to find the places that have the most and least health cover, as well as where the most people avoid visiting the doctors due to financial difficulties.

Where do the most people avoid seeing their doctor due to cost?

Here we can see the proportion of adults in each state that have avoided seeing the doctor for twelve months or more due to the cost of appointments.

Where do most people avoid seeing their doctor due to cost?

1. Mississippi – 19.2%

Mississippi is the state with the highest proportion of its adult population that has not seen a doctor for a year due to financial concerns, with as many as 19.2% of people falling into this category. That’s almost a fifth of the entire state’s adult population!

2. Texas – 17.9%

The second-largest state with the second-largest population, Texas also has the second-highest number of people not visiting the doctor due to cost, with 17.9% of the adult population. With a state population of almost 29 million, that’s a lot of Texans!

3. Louisiana – 17.6%

After Texas comes neighboring Louisiana, where 17.6% of adults have avoided visiting the doctor for a year or more.

This highlights the difficult choices that many people have to make about balancing their health and their finances, not just in these top few states, but across the entire country.

The states with the least health insurance cover

We’ve taken a look at rates of health insurance coverage across all 50 states, and these are the ten with the largest proportion of uninsured residents.

The states with the least insurance coverage

1. Texas – 17.3%

Texas takes the top spot for the state with the largest proportion of its population having no health insurance. Whether Texans forgo health cover for monetary reasons or are simply less concerned about being covered, that’s an incredibly large number of people at risk of falling ill without any idea of how they’ll be treated.

2. Oklahoma – 14.2%

In second place, with 14.2% of its population having no health insurance, is Oklahoma. Having also come tenth in terms of the number of people avoiding the doctors due to cost, Oklahoma’s residents could certainly benefit from more widespread and affordable healthcare.

3. Alaska – 13.7%

Alaska comes third with a sizeable 13.7% of residents not having any health cover. This vast northern state is known for its hardy inhabitants, but they need access to healthcare just like anyone else, and there’s clear room for improvement here.

The state capitals with the least health insurance

Here we take a closer look at the proportion of the population in each of the state capitals that has no health cover.

The states with the least health insurance

1. Trenton, NJ – 18.20%

Trenton comes out as the state capital where residents have the least health cover, with 18.2% being uninsured. This is a stark contrast to state-level cover, where only 7.73% of people have no health insurance. This demonstrates that even in a state where the vast majority have health cover, there are disadvantaged communities struggling to address their health needs.

2. Nashville, TN – 15.20%

The state capital with the second-highest proportion of uninsured residents is Nashville, where 15.2% of the population has no health cover. Again, Tennessee did not appear in the ten states with the least healthcare coverage, which illustrates how much health insurance rates can vary across within a single state.

3. Santa Fe, NM – 14.80%

In third place is the state capital of New Mexico, Santa Fe, where 14.8% of residents have no health insurance. This is 2% higher than the state level, where 12.8% of people are uninsured.

The states with the most health cover

These are the states where the most people are covered by health insurance:

The states with the most health coverage

1. Massachusetts – 97.20%

Massachusetts comes top of the list with only 2.8% of the population having no health cover.

2. Hawaii – 96.15%

In second place is Hawaii, where only 3.85% of people are with any health insurance.

3. Minnesota – 95.61%

Taking third place is Minnesota, with as few as 4.39% of its 5.61m population being uninsured.

The state capitals where the most people have health insurance

Here you can see the state capitals with the most insured populations:

The state capitals with the most health insurance

1. Montpelier, VT – 97.60%

The state capital with the highest proportion of residents having health insurance is Montpelier, VT, where only 2.4% of people have no health cover. Vermont was also the 4th most insured state with 95.45% of the population being covered by some form of health insurance.

2. Honolulu, HI – 96.51%

Honolulu is the state with the second-lowest rate of uninsured people, with only 3.49% of the population having no health insurance.

3. Boston, MA – 96.38%

With only 3.62% of the population being uninsured, Boston is the state capital with the third-highest level of health insurance cover.

See below for our full data on the rate of health insurance in all 50 states and state capitals, as well as the full data set for where the most people avoid seeing the doctor due to the cost.

US states with no health insurance

Methodology

We wanted to find out which states had the highest and lowest levels of health insurance cover. To find this out, we used data from datausa.io which gave us the percentage of the population of each state that was uninsured. This allowed us to rank the states according to this factor.

We then examined the data to find out which state capitals had the highest and lowest rates of insurance, and were, therefore, able to draw comparisons between the state-wide level of insurance cover and that of the capital. We also used the data to find out which state had the highest proportion of adults that don’t go to the doctors due to cost.

By finding these three factors, we were able to create a picture of the state of health insurance across the country.

Capitals

 

If you’re struggling to pay for your medication, we may be able to assist. NiceRx provides access to FDA-approved medications, including Eliquis, Lantus, Apidra, Entresto and Jardiance.

Can diabetics eat fruit?

The simple answer is yes, but we need to look at this deeper. Fruit can be part of a well-balanced diet for diabetics, having said that, if you are diabetic, you will need to be careful how much fruit you consume. Fruit is rich in carbohydrates and diabetics can have a difficult time breaking them down and digesting them normally. In the past, people with diabetes would simply be told to avoid eating fruit. Carbohydrates in fruit are broken down into simple sugars, impacting blood sugar levels directly – that is why the fruit you eat needs to be considered carefully. It is important to learn which fruits affect you the most.

Fruit and diabetes

The main type of nutrient that raises blood glucose levels is carbohydrates. Carbohydrates are found mainly in starchy and sugary foods including fruit. When broken down carbohydrates become simple sugars called fructose. Fructose enters the bloodstream and is metabolized quickly by the liver. In the process of it being broken down, fructose is capable of bypassing an enzyme that signals when cells have had too much sugar. Fructose can raise your blood sugar levels, but does this mean that fruit is bad for diabetics? The answer is no, but consideration does need to be taken on the type of fruit you eat.

The glycemic index of fruits

For a person with diabetes, one way to select safe and suitable fruits and other high-carbohydrate foods is to check the glycemic index (GI). To provide energy carbohydrates must be changed into glucose. Some are converted quickly (high GI foods) and some are converted slowly (low GI foods). Carbohydrates can be grouped into three groups – high, medium, and low GI foods. This is known as the glycemic index of foods. It is measured on a scale from 1 to 100. According to the American Diabetes Association (ADA) glycemic index scores are rated as; low 55 or below, moderate 56-69, and high 70 and above. Foods that digest rapidly cause less harm to your system and have a low glycemic index.

The glycemic load (GL) is another measurement that diabetics need to be aware of. It looks at how different serving sizes of different foods compare to each other. The combination of a low glycemic index and a low glycemic load is better for helping to control blood sugar levels in diabetics.

A note on fiber

The fiber in the body keeps your body in good working order. It passes through your body undigested and therefore adds no calories. Fiber is either soluble or insoluble and having a variety of both is good. Soluble fiber can dissolve in water and can lower blood glucose and fat levels (mainly cholesterol). Insoluble fiber also called ‘roughage’ cannot dissolve in water and helps prevent constipation. Foods containing fiber like fruit have been shown to create a feeling of fullness meaning you may eat less food and have fewer food-based cravings. As fiber is undigested by the body it does not affect your blood sugar levels. This is a benefit in managing your diabetes.

Best fruits for diabetics

The best fruits are those that have a low glycemic index, of 55 or less:

  • Apple
  • Banana
  • Strawberries
  • Blackberries
  • Pear
  • Peach
  • Cantelope

The most important aspect of these low glycemic index foods is that they are slow energy-producing carbohydrates and they contain fiber.

Fruits to avoid with diabetes

  • Pineapple
  • Raisins
  • Figs
  • Grapes
  • Mangoes
  • Watermelon

These fruits have a high glycemic index value therefore should be avoided as they cause a spike in blood sugar levels.

Best ways to eat fruit

  • Watch your portion sizes, especially with dried fruit
  • Choose fresh or frozen fruit when you can
  • When you eat dried or processed fruit, check the label
  • Go easy on the fruit juice. It’s high in carbs
  • Spread your fruit out over the day

How much fruit should you eat?

When deciding how much fruit to eat the glycemic index (GI) and glycemic load (GL) need to be considered. Eating low GI food will keep your blood sugar under control but the portion you consume will affect it too. A large serving of low GI food will usually raise your blood sugar as much as a small amount of high GI food. For example, a pear has a GI of 38 but a GL of 4, which is low. A candy bar with a GI of 55 may have a GL of 22 which is high. Being aware of both the glycemic rating and glycemic load can help you to avoid carbohydrates that absorb too quickly into your system.

In general, a single portion of fruit is one piece of whole fruit or a 1/2 cup of sliced fruit. This contains roughly 15 grams of carbohydrates, which is considered one carb serving. Most adults with diabetes should eat 3 to 4 carb servings per meal and 1 carb serving per snack, though you should check with your doctor to develop an individualized eating plan.

The serving size varies depending on the fruit. 15g of carbs from different fruits looks like this:

  • ½ medium apple or banana
  • 1 cup of blackberries or raspberries
  • 3/4 cup blueberries
  • 1 ¼ whole strawberries
  • 1/8 cup raisins

Health benefits of fruit

Fruit is high in fiber, nutrients, and oxidants as well as providing a great number of vitamins, minerals, and phytochemicals. Phytochemicals are powerful plant compounds that can help lower your risk of heart disease, cancer, and stroke, which is an added bonus because diabetics are normally at higher risk of these conditions. The fiber in fruit also gives you that feeling of fullness and helps to slow down your digestion. Eating fruits will help you to avoid overeating and to maintain a healthy body weight.

Fruit and diabetes FAQs

Can diabetics eat bananas?

Bananas like any other fruit need to be considered carefully by diabetics. As a rule, the more green the banana is the less sugar and more fiber it contains. And it won’t cause a spike in your blood sugar. The amount of sugar in a banana depends on its size and its ripeness.

Is cantaloupe good for diabetics?

Yes, cantaloupe is good for diabetics as the high amount of liquid provide a low glycemic load which means that your body digests it slow and it won’t cause a spike in blood sugar.

Are cherries good for diabetics?

While cherries can be a tasty and healthy part of your diet as cherries contain vitamin C, fiber and potassium, based on the glycemic index of cherries,  it is advisable to portion control when eating cherries.

Can type 2 diabetics eat fruit?

Yes. When choosing which fruit to eat consider its glycemic index and portion size – this is important.

Should diabetics eat grapes?

If you would like to eat grapes you can! As with any fruit you need to take into account its glycemic index. 1 cup serving of grapes is a sensible amount for you to eat.

What fruit has the most sugar?

  • One whole mango – 45g of sugar. Maybe eat a few slices instead.
  • Grapes – 1 cup has 23g of sugar. You could slice them in half and freeze them to make them last longer.
  • Cherries – 1 cup has 18g of sugar
  • Pear – medium-sized has 17g of sugar
  • Watermelon – medium wedge has 17g of sugar

What should diabetics eat for breakfast?

Studies have shown higher protein, higher fat, lower carbohydrate breakfasts are best for diabetics. This can help to improve your blood sugar control throughout the day and help with weight loss. A good breakfast should consist of fiber e.g wholegrain bread or oatmeal, lean protein such as eggs or fish, healthy fats, found in avocado or coconut, and non-starchy vegetables like leafy greens or peppers. For breakfast recipes visit Diabetes Food Hub in association with the American Diabetes Association.

What vegetables should diabetics avoid?

Vegetables are divided into two groups; starchy and non-starchy vegetables. Starchy vegetables such as potato, corn, peas, butter squash, and vegetable juices are higher in carbohydrates so should be avoided by diabetics.

What food lowers blood sugar?

Blood sugar can be lowered by a number of different foods; broccoli, seafood, pumpkin seeds, nuts, nut butter, okra, flaxseeds, beans and lentils, and kimchi are to name a few.

What should diabetics not eat?

It is a good idea to avoid some of the following foods as a diabetic; sugary beverages, trans fats (found in peanut butter, creamers, crackers) white bread, white rice and white pasta, fruit-flavored yogurt, and sweetened breakfast cereals. These foods can all increase your blood sugar levels.

6 best drinks for diabetics

Diabetes is when your body doesn’t use the insulin in your body properly. This can lead to higher blood sugar levels which can create other health problems.

If you are diabetic you need to think not only about the food you eat but also what you drink. Drinks that are high in sugar can lead to spikes in your blood sugar levels. These spikes can be dangerous if you have diabetes.

Here we will look at the best and worst as well as drinks to be cautious of if you are diabetic.

What kind of drinks can a diabetic drink?

When choosing a drink there are some things you need to take into consideration, as even healthy options can affect your diabetes. It’s always a good idea to read the food label on the packaging as this will tell you the contents of that food or drink. You need to be especially mindful of the sugar and carbohydrate content, as high concentrations of these can cause blood sugar spikes. Below is a recommended diabetic drinks list.

Best drinks for diabetics

1. Water

Water is the best drink for diabetics to keep hydrated, whether you have diabetes or not. Your body needs to maintain a healthy water balance for good physical and mental health. Water is readily available and also a good way to stop you from eating unhealthy snacks. The body can sometimes misread thirst as hunger, so next time you fancy a snack, try a glass of water instead and see if you still feel hungry after. Also, water does not contain any calories and so is a great way to stop you from putting on weight.

2. Flavored water

If you find plain water a bit boring you can add some flavor naturally by adding slices of citrus fruit such as orange or lemon. Try adding some berries, cucumber slices, herbs, or mint leaves. Doing this will add flavor without adding a lot of sugar or calories.

In one study it has been shown that adding aloe vera pulp to water may actually be of benefit to people with diabetes.

3. Tea

Tea is a good drink for diabetics, depending on which type you take and how you enjoy taking it. Whether you choose black, herbal, or green tea you should choose those without added sugars. Tea can be hydrating, but also has a range of reported health benefits

  • Green tea is reported to improve blood pressure and LDL cholesterol levels
  • Herbal tea is believed to have anti-inflammatory properties
  • Licorice root, which can be boiled for tea has been shown to lower blood sugar levels in lab rats and may have a similar benefit in people

It is advised however that patients with type 2 diabetes should limit their caffeine intake as consuming 500 mg of caffeine has been shown to increase blood glucose levels in a short period of time.

4. Coffee

There is debate as to whether coffee for people with diabetes is good or bad. Two studies conducted have reported conflicting results. In 2004, scientists who carried out a review concluded that coffee intake may have undesired short-term effects, but that long-term coffee drinking shows some benefits. In 2017, another study concluded that “five of the seven studies suggest caffeine intake increases blood glucose levels and prolongs the period of high blood glucose levels.” It is clear from these results that further research is needed to find out exactly how caffeine affects blood sugar levels.

Something to also think about is how you drink your coffee. Some barista coffees also contain flavored creamers and syrups that contain high levels of sugar. Black coffee is a better choice for people with diabetes as it has no sugar and is very low in calories.

5. Milk

Low-fat or skim milk is another good choice for hydration whether it be cow milk, coconut milk, rice milk, or nut milk. They all provide calories, vitamins, and minerals. Choose unsweetened versions, as these give a more blood sugar-friendly option.

Soy and rice milk add carbohydrates to your diet, so you must account for this in your meal planning. Many dairy milk alternatives lack vitamin D and calcium unless they’re fortified. Fortified nut or coconut milk are dairy-free, low sugar options.

Most unsweetened nut milk has little carbohydrates, but you should check the nutrition facts of your milk of choice and be mindful of how many carbs are in one serving. Knowing this is essential when managing your blood sugar.

6. Vegetable juice

Leafy green vegetables such as spinach or kale can be blended with celery and cucumber for a boost of vitamins and minerals that is also low in carbohydrates. You can add some berries for a better flavor, but be careful not to overdo them as berries contain sugar and carbohydrates too.

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Worst drinks for diabetics

1. Regular soda

You should avoid sugary drinks whenever possible. They raise your blood sugar levels but also account for a large portion of your daily recommended calorie intake. One regular-sized soft drink has the same sugar and calories as eating 10 teaspoons full of sugar.

Sugary drinks add little if any nutritional value to your diet. They have been shown to cause weight gain as well as dental problems. Excess weight is a known risk factor for developing type 2 diabetes. If you already have diabetes these drinks can lead to large spikes in your blood sugar levels, so it is best to avoid these drinks completely, or at the very least, limit your intake.

2. Energy drinks

The problem with energy drinks is that they can be high in sugars and caffeine and they can cause sudden increases in your blood sugar levels. They have also been shown to cause insulin resistance. Insulin resistance is known to increase your risk of developing type 2 diabetes and naturally is not advised if you already have diabetes.

3. Fruit juice

Even though fruit juices contain a large amount of natural sugar, you should be fine drinking them, as long as you don’t drink them too often. The problem with fruit juice is that all the good nutrients and fiber have been taken out of the fruit and all you’re left with is the sugary liquid. It is far better for you to eat the whole fruit.

If you do have to drink fruit juice our advice is to avoid fruit-flavored drinks, choose juices that are 100% fruit juice with no added sugars, limit your portion size to 4 ounces or 100 milliliters, or try adding your fruit juice to water instead.

Drinks to be cautious of

1. Electrolyte drinks

You need to be aware of popular hydration drinks and electrolyte drinks for diabetics that claim to be sugarless and healthy. In a lot of cases, sugarless means the sugar has been replaced by artificial sweeteners or other bad sugar substitutes. Bad sugar substitutes can be other forms of sugar such as fructose from corn syrup. Naturally, these electrolyte drinks can cause spikes in your blood sugar levels.

2. Diet soda

Whether diet soda is a healthy alternative is a matter for some debate. These drinks contain artificial sweeteners, which are marketed as a healthy sugar-free alternative to regular soda. Diet soda has been linked to an increase in insulin resistance, and metabolic syndrome, a cluster of conditions that includes increased blood pressure, cholesterol, blood sugar level, triglycerides, and weight gain. Further studies are needed but sugar-free sodas in moderation are safe for most people.

3. Protein drinks

Most protein drinks are used to maintain or build muscle mass, and there is plenty of choice on the market. However, a lot of these protein drinks also contain high carbohydrates and sugars. Whether a protein drink is suitable for a diabetic will depend on the carbohydrate and sugar content. It’s always best to read the small print so as to be clear on what quantities you’ll be getting from each portion. Remember to factor this into your daily calorie intake.

4. Alcohol

If you have diabetes you can still drink alcohol, but you will need to be careful as to how much you consume. Some facts with regards to alcohol and diabetes:

  • It has been found that men who drink alcohol have an increased risk for type 2 diabetes, while the effects on women vary depending on how much alcohol they consume. Current guidelines recommend one drink a day for women and two drinks a day for men.
  • High consumption of alcohol has been seen to increase type 2 diabetes and prediabetes.
  • The worst alcoholic drinks for diabetics are those high in sugar and carbohydrates. Beer contains carbohydrates and alcoholic mixers contain sugar, this could cause spikes in your blood sugar levels and cause weight increase. Mixers such as sparkling water are recommended rather than regular soda or other diet alternatives. Also, you should check the calorific content of the alcoholic drink before consumption.
  • Alcohol can cause a drop in blood sugar (hypoglycemia) by affecting how the liver produces glucose. Hypoglycemia symptoms can be similar to those of being drunk. Consuming alcohol with food can reduce the chance of hypoglycemia as it is absorbed into your body slower.
  • Overconsumption of alcohol can cause liver disease and other health-related problems. It is advised to always drink in moderation.
  • Alcohol can interact with your medication, check with your doctor to be safe.

Healthy homemade swaps

Sometimes what may seem to be a healthy drink can turn out to be not so good for you, especially when they are shop-bought. You can quite easily make your own healthier homemade versions which will not only be good for your diabetes but are also very tasty and satisfying. Here are a few examples:

1. Lemonade

This is an easy refreshing drink you can try. All you need is water, sliced lemons, and ice. It really doesn’t get any simpler than that.

2. Fruit smoothies

Pop some strawberries, blackberries, bananas, and ice in a blender, or choose another combination you prefer. This healthy option will have less than half the carbs in a smoothie you would buy in a store, and it will keep those hunger cravings away.

3. Hot chocolate

The problem with a lot of hot drinks from coffee houses is that they are high in sugars, carbs, and calories. An alternative way to enjoy your favorite hot drink is to simply use healthier options for ingredients such as almond or soy milk, zero-calorie sweetener, and dark chocolate if you must. It’ll taste just as good and be a much better option for your diabetes.

Drinks for diabetics FAQs

Is Coke Zero OK for diabetics?

So, Coke Zero contains zero calories and zero sugar. It does however contain artificial sweeteners, and as mentioned with diet soda, artificial sweeteners have been linked to insulin resistance and metabolic syndrome. Further studies are needed to evaluate their safety, but drinking in moderation should be safe for most people.

Is Gatorade good for a diabetic?

Gatorade has a high glycemic index of 89 that means that Gatorade will cause a spike in blood sugar levels which causes problems for diabetics who are recommended to avoid substantial changes in blood sugar levels.

Is ginger ale good for diabetics?

Ginger itself can be an effective addition to your diabetes treatment if you use it in moderation. Eating up to 4 grams per day may actually help to regulate insulin production and lower your blood sugar levels. Ginger ale however contains sugar, fructose, or artificial sweetener, all of which can cause blood sugar level spikes. As with other soda drinks, it is recommended to drink ginger ale in moderation.

What drink lowers blood sugar?

Drinking water regularly could lower blood sugar levels, rehydrate the blood, and reduce your diabetes risk. It’s always recommended to drink water and other zero-calorie drinks.

Can diabetics donate blood?

Donating blood is an act of kindness and a selfless way to help others in need. Blood donations allow blood transfusions to be given to people during surgery. Blood is also essential to treat a range of conditions. Sometimes a blood transfusion saves a life. In fact, 1 pint of blood donated can help up to 3 people, so a single donation could even save multiple lives.

However, blood is in short supply in the US. Blood cannot be made artificially, so all blood used in the healthcare system has to be donated. Someone in the US needs blood approximately every 2 seconds, but supplies are low in many areas of the country. The COVID-19 pandemic has made the situation even worse, as fewer people are now visiting blood banks to make donations.

Giving blood is one of the best ways you can help your community, but what about if you have diabetes? Can diabetics give blood?

Here we explain everything you need to know about donating blood for diabetics. We focus on whole blood donation, as this is the most common. But you can also donate blood platelets and blood plasma. The details are very similar for plasma and platelet donation, and what we say here broadly applies to all.

Is it safe for diabetics to donate blood?

It is only natural to be concerned about giving blood if you have diabetes.

Diabetics often have higher levels of glucose in their blood than non-diabetics. Blood with too much glucose does not store as well as blood with a standard level of glucose. You may also have higher levels of insulin in your blood if you inject insulin, plus you may have other diabetic medications present in your blood. So, is your blood safe to donate?

As a general rule, it is safe for diabetics to donate blood as long as:

  • Your diabetes is under control (you are taking medications and making lifestyle changes that keep your blood glucose within a safe range)
  • You are otherwise in good health and you meet the criteria for donating blood

If you plan to give blood, it is sensible to talk to your healthcare provider first to get their perspective and their advice.

Does it matter if I have type 1 diabetes or type 2 diabetes?

No. Put simply, it does not matter if you have type 1 or type 2 diabetes if you want to give blood. What matters is that you meet the above two requirements for giving blood with diabetes – that your diabetes is under control and that you meet the criteria for donating blood.

Factors that may prevent me from donating blood

If you have diabetes, the first factor that can prevent you from giving blood is that your diabetes is not sufficiently under control. If you struggle to keep your blood glucose levels within the target range set by your healthcare provider, your blood may not be suitable for donation and donation may not be right for you.

You also must meet the requirements of the blood bank or other organization you want to donate blood to. These can vary by blood bank or organization. Typically, you must weigh over 110 pounds and be:

  • In good health
  • Free of any symptoms of illness
  • Over 17 years of age (in most states)

You should check the eligibility requirements to give blood in the location you plan to donate in case they have any additional requirements.

Some medications can make you ineligible to donate blood. These include immunosuppressant and anticoagulant medications, but no diabetes medications should make you ineligible.

There is one exception to this. If you have previously taken insulin made from cows (bovine insulin) since 1980. This is because the insulin carries a (very low) risk of carrying Creutzfeldt–Jakob disease (also called mad cow disease). Speak to your healthcare provider if you have any concerns about this.

The blood donation process

The blood donation process will vary by location, but the following is typical. The process usually takes around 1 hour from start to finish.

Before you donate, you will be asked for your ID and to fill in paperwork, particularly if it is your first time as you will need to register as a blood donor. You will likely be asked a set series of questions about your health and will have your blood pressure, pulse rate, and temperature taken.

When you donate blood you will sit in a comfortable chair and a nurse or other healthcare worker will swab your arm to sanitize it. They will then insert a needle into a vein. Blood will drain out of the needle, through an IV tube, and into a collection bag. It takes around 8 to 10 minutes to donate a pint of blood, and you usually donate 1 pint at a time. If you donate blood platelets or plasma, an apheresis machine is used. It can also take longer – up to 2 hours at a time.

After donating, the nurse or other healthcare worker will remove the needle and apply a bandage to your arm. You will usually be asked to rest in place for 15 minutes and you may be offered snacks. You should bring your own diabetes-friendly snacks with you. After you have rested and if you feel fine, with no dizziness, you can leave.

Diabetics can usually give blood every 56 days, but you may have to wait longer if your blood glucose levels are disrupted after donating.

How to prepare for donating blood?

There are a few steps you can take in the days before you donate blood, including:

  • Eating a balanced diet that is rich in nutrition and low in the types of food that can disrupt your blood glucose levels (link to Foods to Avoid with Diabetes )
  • Eating iron-rich foods like meat, fish, nuts, seeds, beans, and green vegetables
  • Drinking plenty of water
  • Making sure you sleep well the night before your donation
  • Trying to avoid stress, strenuous activities, and tough exercise

You should also make sure you bring a source of ID with you on the day (like a passport or driving license) and a list of any medications you are taking. Also, take the equipment you usually use to measure your blood glucose at home just in case you are asked to measure your blood glucose before or after making your donation.

Monitoring blood glucose levels post-donation

You should pay close attention to your blood glucose levels after giving blood. Some type 1 diabetics have reported raised blood glucose levels 3-5 days after donating. Even if you have type 2 diabetes, it is sensible to stay on top of your blood glucose just to be sure.

It is recommended to eat iron-rich foods after giving blood, as your body will lose iron in the red blood cells you donate. Iron-rich foods include meat, nuts, and beans.

In general, you should also:

  • Avoid strenuous activity and exercise for 24 hours after donating
  • Rest if you feel lightheaded
  • Drink more fluids after donating blood – ideally water

Blood donations for diabetics FAQs

Can type 1 diabetics donate blood?

Yes. You can donate blood if you have type 1 diabetes as long as your diabetes is controlled, and your blood glucose levels are within safe limits. You must also be in good health otherwise and meet the donation criteria of the blood bank or organization where you plan to give blood.

Can type 2 diabetics donate blood?

You can donate blood if you have type 2 diabetes if your diabetes is controlled, and blood glucose levels are within safe limits. You will also need to be in good health generally. The blood bank or organization where you plan to donate blood will also provide specific eligibility criteria.

Can you donate blood if you take metformin?

Some medications can prevent you from giving blood, like anticoagulants, but no diabetes medications should prevent you from donating blood. The one exception to this is that you cannot give blood if you have taken insulin made from cows (bovine insulin) since 1980. Talk to your healthcare provider if you are concerned about this.

Can you donate plasma with diabetes?

Yes. You can donate blood plasma if you have diabetes as long as:

  • Your diabetes is controlled, and your blood glucose is within safe limits
  • You are otherwise in good health
  • You meet the eligibility criteria of the blood bank or organization where you plan to donate blood

Giving blood with diabetes

Giving blood is one of the most gracious and important acts you can do to help others. Donating blood is particularly beneficial now that reserves of blood in the US are so low. The good news is that you can give blood if you have diabetes, as long as your diabetes is under control and you are otherwise healthy.

At NiceRx, we want to help people better understand diabetes, how it affects peoples’ lives, and how you can treat diabetes. Read more about diabetes, as well as more about insulin and the top four diabetes medications:

If your doctor has prescribed a diabetes medication to you, you may be able to receive your prescription for only $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for prescription assistance.

Early signs of diabetes

How can you tell if you are – or a loved one is – developing diabetes?

It is not always easy. Diabetes symptoms can come on slowly and the warning signs of diabetes can be difficult to recognize. This is especially the case with type 2 diabetes. Type 1 diabetes symptoms usually appear and develop faster, but it can still take time to realize you have the condition.

If you are at risk of diabetes or are otherwise worried you may be developing it, it is important to know what early warning signs to look out for. To assist, here we explain what the early signs of diabetes are for both type 1 and type 2 diabetes.

Early symptoms of diabetes

Diabetes is a group of diseases that make it more difficult to absorb glucose from your blood. Glucose is released as you digest food and drink. It then passes into your bloodstream so it can be carried around your body and taken to the cells that use it for energy. This process is assisted by insulin – a hormone made by your pancreas and secreted into your blood.

If you have diabetes, this impacts the ability of your cells to absorb glucose. Specifically, your pancreas may not produce enough insulin, and/or your cells will become less sensitive to insulin (insulin resistance). This causes glucose to build up in your blood to a level that can begin to damage your body.

Having too much glucose in your blood can cause these early symptoms of diabetes:

  • Tiredness: The cells of your body stop receiving as much glucose as they need. They, therefore have less energy, making you feel tired.
  • Hunger: Your cells send signals saying they do not have enough glucose, which makes you feel hungry.
  • Peeing more often: One way for your body to remove excess glucose from your blood is for your kidneys to filter it out. Your kidneys make more urine to get rid of this glucose and you have to pee more often.
  • Thirst: Because diabetes makes you pee more often, your body loses more water, making you feel thirsty.
  • Dehydration, a dry mouth, itchy skin: As your body loses more water than usual, you can get dehydrated. Signs of this include having a dry mouth and dry and itchy skin.
  • Blurred vision: Having less water and fluids in your body can also cause blurring and other vision changes by making your eyes swell.
  • Slow-healing cuts/sores: Diabetes can cause nerve damage which slows down how fast your body heals.
  • Yeast infections: Both men and women can get outbreaks of yeast infections as the yeast feeds on excess glucose in areas of your body. This occurs most often in the mouth and armpits as well as around the genitals.

Early signs of type 1 diabetes

Type 1 diabetes is an autoimmune disorder. It is caused by your immune system mistakenly attacking the beta cells in your pancreas that produce insulin, in turn lowering how much insulin you have in your body.

It comes on quickly in most people, although the early signs of type 1 diabetes can be hard to spot or can be mistaken for something else at first. The condition most often emerges during childhood, so if you have diabetes in the family, you should watch for early warning signs of diabetes in your children.

As well as the above early symptoms of diabetes, the early warning signs of type 1 diabetes include:

  • Unexplained weight loss: As your cells receive less glucose, they begin to burn fat for energy instead. This can make you lose weight even though you have not changed what you are eating.
  • Nausea and vomiting: When your body burns fat for energy, your liver first converts stored fat into a type of fatty acid called ketones. The ketone fatty acids are then secreted into your blood so they can be transported in your bloodstream to your cells. If you have high levels of ketones in your blood it can make you feel sick and cause you to be sick. In severe cases, it can also lead to a life-threatening condition called diabetic ketoacidosis.
  • Sweet-smelling breath: Having high levels of ketones in your blood can make your breath smell sweet or fruity.

Early signs of type 2 diabetes

Type 2 diabetes is caused by cells in your body becoming resistant to insulin (insulin resistance). This means insulin stops working as well as it should, and your cells absorb less glucose from your blood. Sometimes your pancreas also begins to produce less insulin.

Insulin resistance is caused by a mixture of genetics and your lifestyle. Your genes can make it more likely that you will develop insulin resistance, but they do not guarantee it. Sometimes genetics is not involved at all.

Type 2 diabetes is sometimes called lifestyle diabetes, as you increase your chances of developing it if you:

  • Are overweight or obese
  • Store fat around your stomach
  • Are not physically active
  • Have a poor diet that is rich in sugary food, simple carbohydrates, saturated fat, and salt
  • Have high blood pressure
  • Have high levels of bad cholesterol and other fats in your blood called triglycerides
  • Have low levels of good cholesterol in your blood

Other risk factors for type 2 diabetes include:

  • Age – specifically being over 45 years old
  • A family history of diabetes
  • A history of heart disease or strokes
  • Being of African American, Native American, Alaska Native, Asian American, Hispanic/Latino, Native Hawaiian, or Pacific Islander descent

If you have, or a loved one has a combination of these risk factors you should look out for the early warning signs of diabetes above. It is also important to be aware of the following early signs of type 2 diabetes:

  • Tingling, numbness, and pain in your hands or feet: Type 2 diabetes can damage your nerves and circulation, which can cause tingling sensations, numbness, and pain in parts of your body. This often occurs in your hands and feet at first.
  • Areas of dark skin: Diabetes can cause you to develop a skin condition called acanthosis nigricans. It results in areas of dark, soft, velvety skin developing in creases on your body. This includes around your neck, armpits, groin, and around your buttocks.
  • Erectile dysfunction (ED): ED is when a man cannot get or maintain an erection that is hard enough for sex. Diabetes can cause circulation and nerve problems that can make ED more likely or worse.

Getting an early diagnosis

If you have any of the early signs of diabetes or any other reason to think you have diabetes, you should make an appointment to see your doctor right away. Diabetes is a serious condition that can harm your health and lead to severe complications, such as:

  • Nerve damage
  • Heart attacks
  • Strokes
  • Vision loss and blindness
  • The amputation of limbs

The good news is that diabetes can be treated and managed by making lifestyle changes and taking diabetes medications, like insulin. If you have diabetes you need to get it diagnosed as fast as possible so you can begin to treat it, to minimize the damage caused and your risk of complications.

Diabetes early warning signs FAQs

What are the 3 most common symptoms of undiagnosed diabetes?

The three most common early signs of diabetes are feeling hungrier than usual, feeling thirstier, and peeing more often.

What is usually the first sign of diabetes?

The first signs you are developing diabetes include feeling hungrier, thirstier, and peeing more than usual. Other early signs can include feeling tired, blurred vision, yeast infections, and having slow-healing cuts and sores.

Can you reverse early signs of diabetes?

You cannot reverse the early signs of type 1 diabetes, as it is an immune system disorder that cannot be cured. Treating type 1 diabetes can limit the damage it causes and reduce the risk of complications. Type 2 diabetes also cannot be cured, but by treating it you can reverse the symptoms of type 2 diabetes and help it to go into remission.

Can diabetes come on suddenly?

Type 1 diabetes can develop quickly – as fast as a couple of weeks. Type 2 diabetes can develop quickly in rare cases, but more often it develops slowly over time with symptoms emerging gradually.

Reducing your risk of diabetes complications

If you have diabetes, it is important to recognize the early warning signs and get a diagnosis as quickly as possible. The faster your diabetes is diagnosed, the sooner you can begin treating it – this will in turn reduce your risk of diabetes complications.

Keen to learn more about diabetes? Here we detail what you need to know about diabetes prevention and treatment, as well as more info on insulin and the top diabetes medications:

If your doctor has prescribed a diabetes medication to you, you may be able to receive your prescription for only $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for prescription assistance.

What is insulin resistance?

Insulin is a hormone that helps your body to transport glucose sugar from your blood into your cells. Insulin resistance is a condition where insulin stops working as well, meaning your cells do not absorb as much glucose as they should. Insulin resistance can lead to health problems like high blood glucose levels and type 2 diabetes.

The condition is common in the US, with between 26% and 32% of adults having some degree of insulin resistance. This number is rising too, and more and more children are also developing insulin resistance.

Here we explain everything you need to know about insulin resistance, including what causes it and how you can reverse insulin resistance.

Understanding insulin

Insulin is a hormone made by your pancreas, a small organ found behind your stomach. It has a range of functions in your body, but the two most important are to do with maintaining a healthy blood glucose level.

When you eat or drink, glucose sugar is released into your blood as you digest. Your blood then takes it around your body, delivering it to the cells that use it for energy. Insulin in your blood helps your cells absorb this glucose. Insulin molecules attach to the surface of your cells which triggers them to bring glucose transporting proteins to the surface. This then draws glucose into the cell.

If you have more glucose in your blood than your cells need, insulin also signals your liver to absorb and store the excess glucose. It can then be used later when your blood glucose has fallen.

If your cells become insulin resistant:

  • They absorb less glucose from your blood than they should
  • Your liver stops storing as much insulin as it should

What causes insulin resistance?

Insulin resistance causes cells in your muscles, fat, and liver to stop responding as well to insulin. It is not fully understood why this happens, but it is known that the following are associated with it and thought to be insulin resistance causes:

  • High levels of fat in your blood
  • Inflammation in your body
  • A high intake of fructose sugar (from foods that have added fructose sugar like candy, soda, sweetened yogurt, bread, and juice)
  • Being physically inactive

How does insulin resistance develop?

Unless insulin resistance is addressed, it usually worsens over time. As your cells become more resistant to insulin, the amount of glucose in your blood rises and your pancreas releases more insulin to deal with it.

But as insulin resistance continues to worsen, your pancreas must make higher levels of insulin to maintain a healthy blood glucose level. However, your pancreas can become stressed and a point is reached where it stops making more insulin. After this point, your blood glucose continues to rise and reaches a level that begins to harm your body. This can cause prediabetes. And as your blood sugar rises further you can develop type 2 diabetes (or gestational diabetes in pregnant women).

Insulin resistance is at the heart of diabetes and is the leading cause of prediabetes, gestational diabetes, and type 2 diabetes.

Risk factors for insulin resistance

A range of factors increases your risk of developing insulin resistance. Some risk factors are out of your control, but many you can control and you can take actions to address them.

Insulin resistance risk factors out of your control:

  • Genetics (your genes can make you more likely to develop insulin resistance, but do not guarantee it)
  • Age – being over 45 years old
  • A family history of prediabetes or type 2 diabetes
  • Obstructive sleep apnea
  • Polycystic ovary syndrome
  • A hormonal disorder, like Cushing’s syndrome or acromegaly
  • African American, Hispanic, Native American, Asian American, or Pacific Islander ancestry

Insulin resistance risk factors you can control:

  • Being overweight or obese
  • A large waist size and fat stored around your stomach
  • High bad cholesterol (LDL) and low good cholesterol (HDL) levels
  • High blood pressure
  • Being physically inactive – not taking regular physical exercise and spending large parts of the day sitting still
  • Eating a diet rich in sugar, refined carbohydrates, saturated fat, processed foods, and junk food
  • Smoking tobacco
  • High levels of stress for prolonged periods

Insulin resistance symptoms

One of the biggest problems with insulin resistance is that you may not know you have the condition without having a blood test. Insulin resistance initially causes no noticeable symptoms. In fact, the CDC estimates around 84% of US adults who have insulin resistance have not realized it.

Signs of insulin resistance only become noticeable once you have passed the point at which your pancreas is no longer producing enough insulin and you begin to develop prediabetes or type 2 diabetes. Early symptoms of diabetes include:

  • Feeling tired
  • Feeling hungrier and thirstier than usual
  • Peeing more often than usual

Read more about the early signs of diabetes.

Complications of insulin resistance

If insulin resistance is left untreated, it can lead to:

  • Extremely low blood glucose levels if your pancreas releases too much insulin (hypoglycemia)
  • High blood glucose levels as your pancreas no longer produces enough insulin (hyperglycemia)
  • Prediabetes
  • Type 2 diabetes
  • Heart attacks
  • Strokes
  • Kidney disease
  • Eye problems that can lead to vision loss and blindness
  • Nerve damage
  • Cancer
  • Alzheimer’s disease

How is insulin resistance diagnosed?

Insulin resistance is primarily diagnosed by using blood tests. Your doctor or another healthcare professional will take a sample of your blood, then use one or more of the following tests to find out how your body is handling glucose:

  1. Fasting plasma glucose test: This test measures how much glucose you have in your blood after you have not eaten for at least 8 hours. This shows if your baseline blood glucose is in the normal range or too high.
  2. Oral glucose tolerance test: First you take the fasting glucose test above, then you drink a sugary solution, and 2 hours later your blood is drawn again. This shows how your body copes with an influx of glucose and whether your blood glucose level remains elevated.
  3. Hemoglobin A1c test: This test measures your average blood glucose levels over the past 2 to 3 months and shows if your blood glucose has been too high over this period.

In addition to the above tests, a doctor will also ask you questions about your lifestyle, what you eat and drink, how much exercise you get, and your medical history as well as that of your family. They may also give you a physical exam (like taking your blood pressure and weight) and/or measure your cholesterol and triglyceride levels when they take your blood.

Can you prevent insulin resistance?

There are steps you can take to prevent your chances of developing insulin resistance. If you tick several risk factors for insulin resistance or have any other reason to think you are at risk of developing it, you can do the following:

  • Maintain a healthy weight – your BMI should be between 18.5 to 24.9 (talk to your doctor about how best to lose excess weight).
  • Exercise regularlyread more about regular exercise.
  • Eat a healthy diet – choose a diet rich in fresh fruit, vegetables, whole grains, pulses, legumes, nuts, lean meat, and fish. Reduce your intake of sugar, refined carbohydrates, saturated fat, salt, processed food, and junk food.
  • Quit smoking.
  • Reduce your stress levels – try to address causes of stress in your life and do not feel guilty about taking time to relax and enjoy yourself each week.

If you are worried you are at risk of insulin resistance, you should arrange to have regular blood tests with your doctor to stay on top of your blood glucose, cholesterol, and triglyceride levels.

Can you reverse insulin resistance?

The best news about insulin resistance is that it can be reversed. Making lifestyle changes can help improve insulin sensitivity and completely reverse the condition. Try:

  • Losing excess weight
  • Adopting a regular exercise routine
  • Reducing how much sugar, refined carbohydrates, saturated fat, salt, processed, and junk food you eat
  • Eating more fresh fruit and vegetables, whole grains, pulses and legumes, nuts, lean meat, and fish
  • Quitting smoking
  • Reducing your stress levels
  • Making sure you get enough sleep each night

If you have another medical condition that makes insulin resistance more likely such as sleep apnea, polycystic ovary syndrome, or a hormone disorder, treating your disorder can help reduce insulin resistance.

Type 2 diabetes medications can be used if you have developed type 2 diabetes. These medications may also be suitable insulin resistance treatments during earlier stages of the condition. These include:

Treating insulin resistance

Insulin resistance is a common condition. It is also one you should be aware of as it can lead to type 2 diabetes and a range of other health complications. Although insulin resistance is serious, it can be reversed through making lifestyle changes.

If you already have diabetes, lifestyle changes can also help to lower your insulin resistance and can help you manage your condition. Lifestyle changes are just one part of living with diabetes. Diabetes medications are also important in treating it.

If you have been prescribed diabetes medication, you may be able to receive your prescription for $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for prescription assistance.

The side effects of insulin

Diabetes is a group of diseases that cause your blood glucose levels to rise too high, harming your health. A range of medications can help you manage your blood glucose levels and reduce your risk of diabetes complications. However, as with all medications, those prescribed for diabetes can cause unwanted side effects.

The side effects caused by most insulins are usually mild. But in rarer instances, they can cause more serious side effects. Here we explain the different types of medications available for diabetes, the side effects they can cause, and what you can do to reduce the risk of any potential harm.

What medication is taken for diabetes?

The most widely used diabetes medications include:

  • Insulin: You can inject insulin to increase how much glucose your cells absorb. The insulin you inject is the same as the insulin that your pancreas naturally produces, except it can be tailored to be faster or longer acting. Insulin is the most widely used treatment for type 1 diabetes but can also be used to treat type 2 diabetes.
  • Sulfonylureas: A type of oral medication, sulfonylureas work by increasing how much insulin your pancreas produces, raising your insulin levels, and causing your cells to absorb more glucose from your blood. Sulfonylureas are used to treat type 2 diabetes.
  • Biguanides and metformin: Two similar classes of diabetes medication that reduce how much stored glucose is released into your blood and increase how much glucose your cells absorb. You take both medications orally as a tablet. They are used most often to treat type 2 diabetes but can also be used to treat type 1 diabetes.
  • Alpha-glucosidase inhibitors: A group of medications that reduce how much carbohydrate and sugar you break down and absorb when you digest food and drink. This reduces how much glucose sugar is released into your blood. Alpha-glucosidase inhibitors are taken orally as a tablet and are used to treat type 2 diabetes.
  • Thiazolidinediones: A form of type 2 diabetes medication, thiazolidinediones reduce how much fat is available to your cells for energy. This causes your cells to absorb more glucose from your blood for energy instead. You take thiazolidinediones orally as a tablet.
  • Meglitinides: Taken to increase the levels of insulin produced by your pancreas, meglitinides are used to treat type 2 diabetes. The medication is taken orally as a tablet.
  • SGLT2 inhibitors: Taken to reduce how much glucose is recycled back into your blood by your kidneys, causing more glucose than usual to be expelled in your urine. You take SGLT2 inhibitors as a tablet to treat type 2 diabetes.

Common side effects of diabetes medications

The most common side effects caused by diabetes medications may include:

  • Reactions at the site of injection
  • Allergic reactions
  • Swelling of your hands and feet
  • Weight gain
  • Low blood sugar (hypoglycemia)
  • Diarrhea
  • Feeling and being sick
  • Tiredness
  • Dizziness
  • A metallic taste in the mouth
  • Stomach pain and abdominal cramps
  • Headaches
  • Upper respiratory tract infections

Full details on the side effects for each group of insulin medication are given below, including details on rarer but more serious side effects and what you can do to minimize side effects.

Insulin side effects

The most common side effects caused by insulin include:

  • Reactions at the site of injection, such as itching, rashes, skin thickening, or pits forming in your skin (lipodystrophy)
  • Allergic reactions that can cause swelling of your face, tongue, or throat
  • Fluid build-up that causes swelling in your hands, feet, and ankles
  • Weight gain
  • Low blood sugar (hypoglycemia). This can cause you to feel tired, hungry, faint, and easily irritated. It may also cause excessive sweating and dizziness, make you tremble and shake, make your lips tingle, and can give you heart palpitations

Rarer, but more serious side effects caused by insulin include:

  • Serious allergic reactions to the medication that can cause anaphylaxis – a full-body allergic response that can be dangerous
  • Your blood potassium falling too low (hypokalemia) – this can cause you to feel tired and weak, as well as cause leg cramps and constipation. It can also increase the risk of an abnormal heart rhythm that can lead to heart failure
  • Extremely low blood sugar (hypoglycemia) – which can cause blurred vision, sleepiness, confusion, problems concentrating, seizures, loss of consciousness, and comas
  • Heart failure – this is more likely if you take insulin alongside another type of diabetes medication called thiazolidinediones

How can you reduce insulin side effects?

You will minimize your risk of insulin side effects by taking the medication exactly as described by the doctor who prescribed it to you. Talk to your doctor if you experience side effects, as they may decide to alter your prescription.

You can reduce your risk of low blood sugar levels by:

  • Sticking to a daily routine of meals
  • Injecting your insulin at set times each day
  • You can also measure your blood glucose using a blood glucose monitor to make sure you don’t inject insulin when your glucose levels are already low

Weight gain is a common side effect of insulin. Talk to your doctor about changes you can make to your lifestyle, like exercise and diet changes, to help reduce any weight gain.

If you try the above and still find your insulin is giving you unpleasant side effects, you should talk to your doctor about changing the type of insulin you take. There are multiple brands of insulin available. Although they are all similar they have differences and you may find you tolerate some better than others. Common insulin brands include:

Sulfonylureas side effects

The most common side effects caused by sulfonylureas include:

  • Diarrhea
  • Feeling sick
  • Skin rashes
  • Itching
  • Weight gain
  • Low blood sugar (hypoglycemia)

Rarer, but more serious side effects caused by sulfonylureas include:

  • Serious allergic reactions to the medication that can cause anaphylaxis – a full-body allergic response that can be dangerous
  • Inflammation of the liver that can reduce your liver function
  • A fall in red blood cell counts that can cause anemia
  • Extremely low blood sugar (hypoglycemia). This can cause blurred vision, sleepiness, confusion, problems concentrating, seizures, loss of consciousness, and comas

How can you reduce sulfonylureas’ side effects?

You can reduce your risk of side effects and low blood sugar levels by:

  • Taking your sulfonylurea medication exactly as described by your doctor who prescribed it to you
  • Sticking to a daily routine of meals at the same time each day
  • Taking your medication at set times each day

Sulfonylureas can cause some people to gain weight. It is important to talk to your doctor about changes you can make to your lifestyle to help reduce any weight gain. This includes both exercise and diet changes.

If you try the above and find you still have side effects that you cannot live with, talk to your doctor about trying an alternative brand of sulfonylurea. Popular sulfonylurea brands include:

If this does not help your doctor may switch you to another diabetes medication as several of the medications mentioned here can be used in place of sulfonylureas.

Biguanides and metformin side effects

The most common side effects caused by biguanides and metformin include:

  • Diarrhea
  • Feeling sick
  • Being sick
  • Tiredness
  • Dizziness
  • Changes in taste and a metallic taste in the mouth

Rarer, but more serious side effects caused by biguanides and metformin include:

  • A buildup of lactic acid in the blood (lactic acidosis) that can be dangerous and cause comas
  • Low vitamin B12 levels that can cause a vitamin B12 deficiency
  • Very low blood sugar (hypoglycemia), which can cause blurred vision, sleepiness, confusion, problems concentrating, seizures, loss of consciousness, and comas

How can you reduce biguanides and metformin side effects?

You can reduce the common digestive side effects caused by biguanides and metformin by taking your tablets before a meal or on a full stomach. If you take two or three doses of your medication a day, it can also help to spread your doses over the day with equal time between them.

To reduce your risk of low blood sugar levels and other side effects, make sure you:

  • Stick to a daily routine of meals
  • Take your medication at set times every day

Remember to always take your biguanides and metformin medication exactly as described by the doctor who prescribed it to you. Talk to your doctor if you still experience side effects as they may alter your prescription or the brand of medication. Popular biguanides and metformins include:

Alpha-glucosidase inhibitor side effects

The most common side effects caused by alpha-glucosidase inhibitors include:

  • Bloating
  • Gas
  • Diarrhea
  • Abdominal cramps
  • Stomach pain

Rarer, but more serious side effects caused by alpha-glucosidase inhibitors include:

  • Serious allergic reactions to the medication that can cause anaphylaxis
  • Inflammation of the liver that can reduce your liver function
  • A fall in blood platelets counts that can result in bleeding problems, as your blood cannot clot
  • Pockets of gas forming in your lungs (pneumatosis intestinalis)

How can you reduce alpha-glucosidase inhibitor side effects?

  • Take your medication exactly as directed by the doctor who prescribed it to you to minimize your chances of side effects
  • Most of the common side effects of alpha-glucosidase inhibitors affect your digestive system. These tend to be short-lasting and they often go away as your body gets used to the medication. It can help to start on a low dose and gradually build up to give your digestive system time to adjust to the medication

If side effects persist talk to your doctor about trying an alternative brand of alpha-glucosidase inhibitor. Common brands include:

If this still does not help, talk to your doctor about switching to an alternative type of diabetes medication.

Thiazolidinediones side effects

The most common side effects caused by thiazolidinediones include:

  • Headaches
  • An increase in upper respiratory tract infections (like colds and throat infections)
  • Fluid build-up that causes swelling in your hands, feet, and ankles
  • Weight gain

Rarer, but more serious side effects caused by thiazolidinediones include:

  • Heart failure when thiazolidinediones are taken with insulin
  • Bladder cancer
  • Serious allergic reactions to the medication that can cause anaphylaxis
  • An increased risk of broken bones in women
  • Incredibly low blood sugar (hypoglycemia) when used alongside other diabetes medications. This can cause blurred vision, sleepiness, confusion, problems concentrating, seizures, loss of consciousness, and comas

How can you reduce thiazolidinediones’ side effects?

  • Take your medication exactly as directed by the doctor who prescribed it to you to minimize your chances of side effects
  • You can reduce your risk of low blood sugar levels by sticking to a daily routine of meals and taking your medication at set times
  • Thiazolidinediones can cause weight gain, which you can address through making lifestyle changes, like eating a lower calorie diet and exercising regularly. Talk to your doctor about effective weight loss

If the above does not work for you and you still experience side effects talk to your doctor about trying an alternative brand of thiazolidinedione. Popular thiazolidinediones include:

If this does not help talk to your doctor about switching to an alternative diabetes medication. A range of other diabetes medications can be used in place of thiazolidinediones.

Meglitinides side effects

The most common side effects caused by meglitinides include:

  • Stomach pain
  • Indigestion
  • Feeling sick
  • Diarrhea
  • Weight gain
  • Low blood sugar (hypoglycemia). This can cause you to feel tired, hungry, and faint. You may also feel irritated and experience excess sweating and dizziness. You may even tremble and shake, feel your lips tingle, and experience heart palpitations

Rarer, but more serious side effects caused by meglitinides include:

  • Serious allergic reactions to the medication that can cause anaphylaxis
  • Very low blood sugar (hypoglycemia) when used alongside other diabetes medications, which can cause blurred vision, sleepiness, confusion, problems concentrating, seizures, loss of consciousness, and comas

How can you reduce meglitinide side effects?

  • You reduce your risk of side effects if you take your meglitinide medication exactly as directed by the doctor who prescribed it to you
  • You can reduce your risk of low blood sugar levels by keeping to a daily routine of having meals and taking your medication at set times to avoid spikes and falls in blood sugar

If you still experience side effects talk to your doctor about trying an alternative brand of meglitinide medication. Popular meglitinide brands include:

  • Prandin
  • Prandimet
  • Starlix

If this does not help, talk to your doctor about switching to an alternative diabetes medication.

SGLT2 inhibitors side effects

The most common side effects caused by SGLT2 inhibitors include:

  • Nausea
  • Constipation
  • Dehydration
  • Risk of genital yeast infections
  • Risk of urinary tract infections
  • Low blood sugar (hypoglycemia) – causing you to feel tired, hungry, faint, and easily irritated. You may also experience excessive sweating and dizziness. You may tremble and shake, your lips can tingle, and you might experience heart palpitations

Rarer, but more serious side effects caused by SGLT2 inhibitors include:

  • Inflammation of the pancreas
  • Diabetic ketoacidosis – a condition where high levels of ketones build up in your body, that can cause fatigue, confusion, vomiting, and swelling of the brain
  • A rare bacterial infection that damages the tissue under the skin in the area between the anus and genitals (necrotizing fasciitis)
  • Serious allergic reactions to the medication that can cause anaphylaxis, a full body allergic response that can be dangerous
  • Kidney failure
  • Hypoglycemia when used alongside other diabetes medications. This is very low blood sugar levels which can cause blurred vision, sleepiness, confusion, problems concentrating, seizures, loss of consciousness, and comas

How can you reduce SGLT2 inhibitor side effects?

  • Take your medication exactly as directed by the doctor who prescribed it to you
  • Keep to a daily routine of meals and medication at set times to avoid spikes and falls in blood sugar

If the side effects persist speak to your doctor about trying an alternative brand of SGLT2 inhibitor medication. Popular SGLT2 inhibitor brands include:

If this does not help talk to your doctor about switching to an alternative diabetes medication. Many of the other diabetes medications mentioned here can be used as an alternative to SGLT2 inhibitors.

Disclaimer

This article is for informational purposes only and does not constitute medical advice. If you are worried about the side effects of your diabetes medications or have any other concerns or questions about diabetes, talk to your doctor or pharmacist.

If your doctor has prescribed a diabetes medication to you, you may be able to receive your prescription for only $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for prescription assistance.

Top 20 best snacks for diabetics

Eating snacks between meals can stop your blood glucose levels from falling too low. And if you eat regular but small meals, this can also be a more effective way to manage your diabetes than eating a few large meals. Unfortunately choosing the right snacks is not always easy when you have diabetes, especially as most snack foods are high in sugar, fat, and salt.

To help you make the right choices, we explain what type of snacks are best for diabetics, list our 20 favorite diabetes-friendly snacks, and explain what type of snacks diabetics should avoid.

Understanding how food affects diabetes

Eating to manage your blood sugar

Diabetes is a condition that affects how your body deals with the food and drink you consume. It is also affected by factors like your body weight, your blood pressure, and your cholesterol levels. Making the right diet choices is therefore crucial. Whether you have type 1 diabetes, type 2 diabetes, or another form of diabetes. The main issue caused by your condition is that your body does not absorb as much glucose from your blood as it should. This causes glucose to build up in your blood to harmful levels.

The aim of your diet should be to avoid foods that release glucose quickly, thus preventing fast rises of blood glucose. Spikes in blood glucose can also be followed by sharp falls in blood glucose, particularly if you take a diabetic medication shortly before or after eating. This can put you at risk of hypoglycemia.

Eating to stop insulin resistance

Diabetes affects your diet, but your diet can also affect your diabetes. Being overweight, having high blood pressure, low levels of good cholesterol, and high levels of bad cholesterol and other blood fats (triglycerides) are all type 2 diabetes risk factors. They can make it more likely you will develop type 2 diabetes and can make existing type 2 diabetes worse.

It is thought that these risk factors make your body become increasingly resistant to insulin, so the insulin your body produces stops working as well. Insulin resistance can also be a problem if you have type 1 diabetes.

This means that maintaining a healthy body weight, blood pressure, cholesterol, and blood fat levels can help you manage both type 2 and type 1 diabetes.

What to consider when choosing a snack?

Because of the link between diet and diabetes, when choosing a snack, you want food or drink that:

  • Is low in sugar to prevent spikes in blood sugar levels
  • Is high in fiber, as this slows down digestion and causes glucose to be released more gradually
  • Is high in protein, as protein is filling and can cut hunger pangs
  • Is low in calories, to prevent weight gain
  • Is low in saturated fat, to prevent weight gain and high bad cholesterol and triglyceride levels
  • Is low in salt (sodium), to prevent rises in blood pressure
  • Is nutritious, to make sure your body is getting the vitamins, minerals, and other nutrients it needs
  • Is fun to eat, because snacking should be fun as well as sensible

It is of course a tall order to tick all these boxes, but the more goals a snack hits, the better. Here are 20 snacks we have selected to help you meet as many of these goals as possible:

Our top 20 snack ideas for diabetics

A handful of almonds

Almonds are a quick and simple snack that can help with diabetes. Research has shown that regularly eating almonds can help lower blood sugar levels and circulate insulin in people with diabetes.

Almonds are also rich in nutrients, protein, and healthy monounsaturated fats. They are quite high in calories however, so only eat a small handful as a portion and make sure you stick to unsweetened and unsalted nuts.

Hardboiled eggs with horseradish

Make your own deviled eggs by halving hard-boiled eggs and adding a teaspoon of horseradish on top to give them some kick.

Eggs are a true superfood. They are packed with nutrients, high in protein, low in carbs and sugar, and are filling. Using horseradish rather than mayonnaise adds extra taste but avoids the saturated fat found in mayonnaise. A single egg delivers around 150 calories however, so stick to one or two at a time.

Cheese on wholegrain crackers

A classic snack that is quick to prepare and tastes great. Cheese is also high in protein and can satisfy a hungry belly, but always opt for lower-fat cheeses and cheeses without added salt. Make sure the crackers are wholegrain and do not contain refined flour and added sugar that can cause blood sugar spikes.

Sliced apple with peanut butter

Slice up an apple with the skin still on and add a couple of teaspoons of peanut butter to spread onto the apple slices for a quick and tasty snack.

Apples are high in nutrients and fiber, while low in calories. Peanut butter is a great source of protein and healthy unsaturated fat. Importantly, it is also tasty and filling.

A bowl of popcorn

If you make the right choice, popcorn can be a low-calorie snack that can also pack a respectable amount of fiber. Because popcorn is low in calories but high in volume, it can fill your stomach too and stave off hunger pangs.

Make sure you opt for low-fat, low-sugar, and low-salt popcorn that does not have any added flavors or ingredients. Best of all, buy raw corn kernels to pop yourself at home.

Greek yogurt with berries

A small bowl of Greek yogurt with added berries (fresh or frozen) can make a tasty and satisfying snack.

Greek yogurt is lower in sugar than flavored yogurts and higher in protein than other natural yogurts, meaning it can curb your hunger more effectively. Berries are high in fiber, nutritious, low in calories, and add taste and variety to the yogurt.

A bowl of edamame

Edamame beans are soybeans still in the pod. You buy them in frozen bags and cook them simply by boiling until the pods begin to split open for a tasty, diabetes-friendly snack.

Edamame beans are low in calories but high in fiber and nutrients. In Japanese restaurants, edamame beans are served sprinkled in salt, but avoid doing this at home to protect your blood pressure.

Roasted chickpeas

You can roast chickpeas yourself at home with added seasoning like paprika, but you can also buy a range of brands of ready-made, diabetes-friendly roasted chickpeas. Roasted chickpeas are crunchy, tasty, and make a great alternative to chips.

Chickpeas are high in fiber and protein, making them filling despite being relatively low in calories. Research has also shown that regularly eating chickpeas can lower your blood sugar too.

Vegetables dipped in hummus

Continuing with chickpeas (hummus is a dip made from chickpeas), hummus can be a good source of protein and fiber if you choose your brand carefully. Combine it with sliced vegetables, like raw carrot, cucumber, and peppers, and you are adding nutrients and even more fiber.

You can make hummus at home or you can buy ready-made hummus. Always check the label to make sure you buy hummus without added salt or sugar.

A handful of olives

Olives make a quick and simple snack that is high in fiber and nutrients. Olives are also high in monounsaturated fats which have been shown to help reduce blood sugar levels over time.

Olives come in a wide range of colors and flavors, so have enough variety to keep them interesting. They can be relatively high in calories, so limit yourself to a small handful at a time.

Caprese salad

Caprese salad is a simple but tasty Italian salad that takes minutes to prepare. Layer slices of fresh tomato and mozzarella cheese across a plate, add basil leaves, then drizzle over a small amount of olive oil and/or balsamic vinegar, and you are good to go.

Tomatoes and basil are low in calories but nutritious, olive oil contains healthy monounsaturated fats, while mozzarella is relatively low in calories, fat, and salt as far as cheese goes. They combine to make a healthy, filling, visually appealing snack.

Salmon jerky

You can find a wide range of jerkies in your supermarket today. And while they all tend to be low in sugar and carbs, and high in protein, salmon jerky also contains important omega-3 fatty acids that can help reduce the risk of some complications of diabetes.

All jerkies can be high in salt, so whatever form you buy, try to buy a reduced salt alternative and eat only a few strips at a time.

Cottage cheese with fruit

Cottage cheese is low in sugar, carbs, fat and calories, but high in protein, making it a perfect food for diabetics. You can liven cottage cheese up and add more fiber and nutrients by adding fruit like berries, kiwi, pineapple, or slices of mango.

A wholegrain waffle with cinnamon and Greek yogurt

Wholegrain waffles are a healthier alternative to regular waffles. The wholegrain they contain is a more complex carbohydrate that is digested slower and releases glucose into your blood gradually.

Greek yogurt can add protein to your waffles as well as provide a complimentary texture. A sprinkling of cinnamon adds some taste but without added sugar or fat. Cinnamon is great for diabetes in particular, as research suggests it can help lower blood sugar over time.

Peanut butter and sugar-free jelly on whole grain bread

You can still eat peanut butter and jelly sandwiches if you have diabetes, just make sure you use wholegrain bread and sugar-free jelly.

Wholegrain bread is made from complex carbohydrates, so releases sugar slowly into your blood. Sugar-free jelly is a diabetic-friendly alternative to regular sugar-filled jelly.

Dark chocolate covered rice cakes

Sometimes when you crave a snack, you crave something sweet. Make sure you have some dark chocolate-covered rice cakes at hand for these occasions.

Dark chocolate contains less sugar and fat than white or milk chocolate and contains higher levels of healthy cocoa and antioxidants. Rice cakes are low in calories, but bulky which can help to fill your stomach and curb feelings of hunger.

Sugar-free hot chocolate

If you have a craving for chocolate, you can find plenty of sugar-free hot chocolate brands at your supermarket. A cup of sugar-free hot chocolate can satisfy your chocolate cravings but without sugar and fat.

Fruit or mint-flavored water

You might not think of water as a snack, but dehydration can create pangs that are mistaken for hunger. A glass of water can therefore stop you from eating unnecessarily. Staying properly hydrated is also important for diabetics, as dehydration can increase your blood sugar concentration as well as put a strain on your body.

You can add flavor to glasses of water by dropping in slices of fruit, like lemon or lime, or crushed mint leaves.

A cup of tea

Tea can help keep you hydrated and cut feelings of hunger. Some teas are also rich in antioxidants and other nutrients.

Good teas for diabetics include:

  • Green tea
  • Black tea without milk
  • Black tea with low-fat milk or vegan milk
  • Herbal teas
  • Fruit teas that have no added sugar or sweeteners

A cup of coffee

Coffee tastes so good it surely cannot be good for you too. Fortunately, it is. Coffee has high levels of a range of phytonutrients while caffeine can also reduce hunger.

While it was once thought that coffee increased insulin resistance, it is now thought that it is the cream, full-fat milk, sugar, syrups, and other sweeteners that are put into coffee that are responsible. To keep your cup of joe diabetes-friendly, take it black, with low-fat milk or vegan milk only. Do not be tempted to add any syrups or sweeteners.

What snacks should diabetics avoid?

You should avoid snacks high in sugar and simple carbohydrates that can cause spikes and crashes in your blood glucose. Simple carbohydrates are made from refined grains, like white rice and white flour.

You also need to steer clear of snacks that are high in saturated fats and salt, as these can contribute to insulin resistance. Stay away from:

Snacks high in sugar

The following snacks can cause spikes and crashes in your blood glucose:

  • Candy
  • Chocolate
  • Cakes
  • Donuts
  • Ice cream
  • Soda and other sugary beverages, including coffee with sugar and syrups
  • Fruit juice
  • High sugar dairy, such as fruit-flavored yogurts

Snacks high in simple/refined carbohydrates

Simple carbohydrates (also sometimes called refined carbohydrates) are digested quickly and rapidly release glucose into your blood. Snacks high in simple carbohydrates include:

  • Sandwiches made with white bread
  • Wraps made with white tortillas
  • Pastries
  • Bagels
  • Crackers
  • Chips
  • Pretzels

Snacks high in saturated fat and salt

Saturated fat is associated with high levels of bad cholesterol, high blood fat levels, and weight gain. Eating too much salt can also raise your blood pressure. Try to avoid:

  • Fast food, like slices of pizza
  • Any snacks that are fried, like French fries or churros
  • Snacks that contain red meat, like burgers
  • Processed meat, like hotdogs, sausages, and bacon
  • Full-fat dairy, like full-fat yogurt, cheese, and milk

Snacks for diabetics FAQs

Can diabetics snack between meals?

If you have diabetes, eating snacks between meals can help you avoid falls in blood sugar and can help you maintain a healthy blood sugar level.

However, you need to avoid snacks that are high in sugar and simple carbohydrates, to prevent spikes in blood sugar that can sabotage an otherwise diabetes-friendly diet. You should also avoid snacks that are high in salt and saturated fat, as these can contribute to insulin resistance. Aim for snacks that are nutritious and filling as well as high in fiber, protein, and other nutrients.

What snacks can diabetics eat at night?

Eating a snack before bed can help to stop your blood sugar from falling too low as you sleep and can help prevent the dawn effect where your blood glucose levels rise quickly when you wake. Try not to overeat before bed, to avoid blood sugar spikes and weight gain. Aim for snacks that are digested slowly and release glucose into your blood gradually.

Is peanut butter good for diabetics?

Yes. Generally, peanut butter is a good food choice for diabetics. Peanut butter is high in protein and healthy fats. It also tastes great and can liven up other foods like fruit. However, peanut butter is relatively high in calories, so you should limit yourself to a couple of teaspoons per serving. Not all peanut butter is equal too – make sure you buy a brand that does not have added salt or sugar.

Is watermelon good for diabetics?

Fruits are low in calories and nutrient-rich, and fresh fruit can make a healthy and convenient snack. Fruit can be high in sugar, but the fiber in fruit slows down how quickly the sugar is digested and released into your blood.

The carbohydrates and sugars in watermelon are broken down quickly for fruit. You may have heard that watermelon can cause spikes in blood glucose. The reality is that small amounts of watermelon likely will not cause unhealthy rises in blood glucose, but it is sensible to eat watermelon in small amounts until you know how your body reacts to it.

Is oatmeal good for diabetics?

Oatmeal is high in carbohydrates, leading people to worry that all those carbs will be quickly broken down to glucose. However, the oats in good quality oatmeal are a source of complex carbohydrates that are broken down slowly. The fiber content of oatmeal also slows how quickly glucose is released through digestion. Oatmeal is fine for diabetics in small portions of good quality oatmeal. Not instant oatmeal with added sugar. Never add sugar, honey, or other sweeteners to oatmeal. Add fresh fruit, berries, or cinnamon instead.

Is honey good for diabetics?

While honey is sometimes treated as a healthier alternative to sugar, the unfortunate truth is it is not. Honey is a source of sugar just like granulated sugar. It helps to think of honey as liquid sugar that can cause rapid rises in blood glucose. If you have diabetes it is advisable to steer clear of honey, syrup, agave nectar, and other sources of sugar.

Finding the right snack choices for you

Making the right snack choices can help you manage your diabetes. Bear in mind however that food affects people differently, so you may have to experiment to find the best snacks for you. Your diet is important, but it is only one part of living with diabetes. You can make other positive lifestyle changes that help (like getting regular exercise and drinking alcohol in moderation), but medications are central to controlling and living with your diabetes.

Read more about diabetes medications with NiceRx. Learn more about insulin and the top diabetes medications:

If your doctor has prescribed a diabetes medication to you, you may be able to receive your prescription for only $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for prescription assistance.

What foods to avoid with diabetes

Eating the right foods and avoiding the wrong foods in conjunction with physical activity can help you manage your blood sugar levels and reduce your risk of diabetic complications. Eating certain unhealthy foods can raise your insulin levels and blood sugar which could possibly cause inflammation and may increase your risk of disease.

Currently, around 11% of individuals in the United States have type 1 diabetes or type 2 diabetes, Around 35% of the adult population in the country have prediabetes and around 90% of adults with diabetes also are overweight or have obesity, as reported in the 2020–2025 Dietary Guidelines for Americans.

You should follow a diabetes diet meal plan that includes a mix of protein, carbohydrates, and healthy fats, and smaller portions of certain foods including refined carbohydrates and sugars. Eating healthy foods and a low-calorie diet can potentially help put type 2 diabetes into remission.

Understanding food and diabetes

Diabetes affects how your body deals with food, but what you eat can also affect your diabetes. Your diet also influences your risk of diabetes complications.

Eating to avoid high blood sugar

If you have diabetes, your cells do not absorb glucose as fast as they should, meaning glucose can build up to harmful levels in your blood. You need to eat sources of sugar and carbohydrates that are digested slowly and release sugar gradually so that they do not cause a spike in blood sugar, such as:

  • Fruit, vegetables, pulses, and legumes contain fiber alongside sugar and carbohydrates. This slows how quickly the sugar and carbs are digested.
  • Complex carbohydrates (wholewheat pasta and brown rice) are broken down slowly compared to refined carbohydrates (white bread, white pasta, and white rice) which can cause spikes in blood sugar.

Eating to avoid insulin resistance

Insulin resistance is when your insulin stops working as well as it should. It can be a problem for people with either Type 1 or Type 2 diabetes and is linked to high cholesterol levels and high blood pressure, as well as being overweight or obese. Eating foods low in saturated fat and salt can help you avoid insulin resistance.

Eating to reduce the risk of diabetes complications

Diabetes puts you at risk of developing further health complications, including serious ones like heart attacks and strokes. You can reduce your risk of these complications by cutting how much salt, sugar, and saturated fat you eat.

Foods to avoid with diabetes

If you have diabetes, you should avoid foods that are high in:

Sugar

If you have diabetes, eating too much sugar could lead to kidney damage. The kidneys are essential for filtering your blood. Once blood sugar levels reach a certain amount, the kidneys could potentially start to release the excess sugar into your urine.

Refined carbohydrates

Refined carbohydrates may contain starch, sugar, and fiber. Starches and sugars are considered high risk for people with diabetes because the body breaks these foods into glucose which is not desirable for diabetics.

Saturated fat

Foods that are high in saturated fats, including fried foods such as french fries, coconut oil and palm oil, are not healthy foods for diabetics to eat as they contain bad fat which increases the risk of heart disease.

Salt

Although salt does not affect blood glucose levels, it is recommended to limit the amount of salt you eat as part of your diabetes management plan because eating too much salt may raise your blood pressure.

17 types of foods and drinks for diabetics to avoid

Here you will find our top 15 foods and drinks for diabetics to cut from their diets:

White bread

You can eat bread if you have diabetes, just make sure it is not white bread. The flower in white bread has been refined to remove fiber, oils, and protein, leaving behind mostly carbohydrates. This reduces the nutritional content of white bread, but more importantly, it means your body digests the carbohydrates faster, causing spikes in blood sugar and insulin.

Diet soda

Drinking soda is an effective way to dump a huge amount of sugar straight into your bloodstream. Soda is digested fast and can contain a scary amount of sugar. One can of soda has around nine teaspoons of sugar in it. But is diet soda a diabetic-friendly alternative?

Unfortunately, diet soda is not a safe alternative for diabetes. The sweeteners in diet soda may not contain any calories, but research has shown they still cause your body to release insulin, making it difficult to manage your blood sugar, and increasing your risk of weight gain and insulin resistance.

Fruit smoothies

Despite what you might have read, you can eat fresh fruit if you have diabetes. Although fruit contains sugar, the fiber in fruit slows down how quickly it is digested and released into your blood. However, you should be careful to eat fruit in moderation, and not eat too much in one go to reduce your overall sugar intake.

Fruit smoothies are a drink to avoid. Much of the fiber in the fruits have been removed and smoothies can pack a lot of fruit into one drink. This means your body receives a huge dose of sugar without the fiber needed to slow how quickly it is released into your blood.

Fruit juices

Drinking fruit juice might sound like a convenient way to make sure you get your five-a-day, but fruit juice causes the same problems as fruit smoothies. Most of the fiber from the fruit is removed and a lot of fruit sugar is compressed into each drink. This means you digest fruit juice fast and your bloodstream receives a quick hit of a large amount of sugar.

Sports drinks

Sports drinks, like Gatorade, Perform and Powerade, are intended to rapidly release sugar and salts into your blood. This is beneficial if you are a high-level athlete who is training hard, but the exact opposite of what you need if you have diabetes.

Sports drinks are high in sugar, a source of extra calories, and for most people totally unnecessary. You only need to drink water to keep yourself hydrated.

Gluten-free foods

Gluten is a healthy source of protein for most people to eat. You only need to avoid gluten if you are gluten intolerant or have celiac disease.

Gluten is a tacky protein too – it helps to give foods bounce and elasticity. When you press a loaf of bread and it bounces back into shape, that is gluten. Gluten-free foods replace this gluten with other tacky substances which are often less healthy – this includes certain fats or carbohydrates. This means gluten-free foods are often higher in carbs and fats and lower in protein than gluten-containing foods.

Processed lunch meat

Slices of lunch meat or deli meat contain high levels of salt – just a couple of slices can pack over half your daily requirement of sodium. Too much salt in your diet increases your risk of high blood pressure and heart disease, so you need to avoid these meats. If you want meat in your sandwiches, opt for unsalted, lean meat like chicken or turkey, or choose fish instead.

Flavored yogurt

Flavored yogurt and yogurts with fruit are often advertised as healthy, low-fat treats. And while it is true that these yogurts may be low in fat, they are not healthy treats as they are usually laden with sugar. One small yogurt can contain six teaspoons of sugar or even more.

Flavored instant oatmeal

Home-made oatmeal is a good choice for diabetics as oats are a source of complex carbohydrates and contain fiber, so they release sugar slowly.

However, instant oatmeal (particularly flavored oatmeal) is a different story. The oats in instant oatmeal are usually pulverized or powdered, meaning they are digested faster and release sugar more quickly. Instant and flavored oatmeal often contains high levels of added sugar and/or salt too.

Mac n’ Cheese

Everyone loves mac n’ cheese, but diabetics should stay away from it. It is usually made with white pasta, full-fat milk, and cheese, and often has added white flour and salt. Pasta and flour are a source of carbohydrates, which will be quickly broken down in your digestive system to release a large amount of sugar quickly. The milk and cheese add saturated fat that can cause weight gain and contribute to insulin resistance, while the salt can increase your blood pressure.

Coffee-shop coffee

A steaming cup of joe with a little low-fat milk is a daily treat you do not need to feel guilty about. But the coffee you buy from coffee shops is usually laden with carb and sugar-rich milk. Any added cream or sugar can boost the fat and sugar content considerably. Stick to homemade coffee and avoid the temptation of coffee shops.

Fast food

We all know fast food is bad for us. Whether it is burgers and fries, pizza, fried chicken, or Chinese takeout, fast food is laden with sugar, saturated fat, and salt. Eating fast food can raise your blood sugar, blood fats, and blood pressure, as well as expand your waistline.

But an occasional treat is OK, right? That depends on how occasional. Research has shown people who eat fast food twice a week can have a level of insulin resistance twice as bad as people who stay away from fast food. If you do eat fast food as an occasional treat, make sure it really is occasional.

Honey

You can find a lot of unscientific claims about honey online, including the idea that honey is not as bad for you as other sugars because it is natural. Sadly, this is not the case. Most sugars are natural, and honey is almost pure fructose. Think of honey as liquid sugar and a food that diabetics should definitely steer clear of. The same goes for agave nectar and syrup.

Jams and jellies

These might seem like healthy choices packed with fruit, but jams and jellies contain heaps of sugar, both from the fruit and from the considerable amount that gets added when the jams and jellies are made.

High sugar cereals

Cereals with lots of sugar and little whole grains should be avoided. Stick to healthy cereals such as shredded whole wheat cereal with low-fat milk that doesn’t contain any added sugar or salt and is also high in fiber.

Alcohol

You need to drink alcohol carefully if you have diabetes. Alcohol is high in calories, simple carbohydrates, and sugar, so you need to drink in moderation and drink slowly to avoid blood sugar spikes. Drinking alcohol after you have taken insulin can also increase your risk of hypoglycemia (falls in blood sugar to low levels) as well.

Full-fat dairy products

You should do your best to avoid full-fat dairy products that are made with whole milk, including cream, ice cream, full-fat yogurt, cream cheese, and other types of full-fat cheeses. Consider healthier alternatives such as fat-free or reduced-fat dairy products instead.

Tips for healthy eating with diabetes

The following healthy eating tips can help you manage your blood glucose levels, keep your blood pressure and bad blood fats down, raise your good cholesterol, and help you lose excess weight.

Switch to healthier carbohydrates

Swap refined carbohydrates like white rice, white pasta, and white bread for brown rice, wholewheat pasta, quinoa, and wholegrain bread alternatives to make sure the carbohydrates you eat release sugar slowly.

Cut out sugary drinks

Cutting out sugary food from your diet entirely is difficult, but you should aim to reduce how much sugar you consume. One simple and effective way to do this is to cut out all sugary drinks, like soda, tea, and coffee with added sugar and syrups, energy drinks, and fruit juice.

Replace them with water, black coffee, or coffee with a small amount of low-fat milk, and herbal and fruit teas that do not have added sugar.

Choose healthier fats

Your body needs a certain amount of fat to be healthy, but not all fats are equal. Saturated fats, found in food like red meat, processed meat, and high-fat dairy products, can damage your health and worsen your diabetes. This is the same for trans fats, found in fast food, cakes, and baked goods.

Unsaturated fats, eaten in the right amounts are healthier and can help you manage your diabetes. Good sources of unsaturated fats are oily fish, olive oil, avocados, nuts, and seeds.

Eat good sources of protein

Your body needs protein to maintain itself. Foods high in protein can also be filling and can help cut hunger pangs. Stick to healthy sources of protein like beans, lentils, green vegetables, nuts, fish and shellfish, and lean meats like turkey and chicken. Avoid red meat, processed meat, and high-fat/high-sugar dairy.

Add plenty of fruit and vegetables to your diet

Fruit and vegetables are packed with vitamins and minerals. Eating plenty in your diet is associated with a lower weight, lower blood pressure, better cholesterol, and less chance of insulin resistance. It can also help to reduce your risk of diabetic complications. Try to include vegetables with every meal and eat fresh fruit if you are tempted to snack.

Snack sensibly

Speaking of snacks, you can snack if you have diabetes. But make sure you do not overeat and avoid snacks high in salt, sugar, or fat. Opt for snacks like fresh fruit, nuts, low-fat and low-sugar dairy, and hard-boiled eggs. Read more about the best snacks for diabetics.

Stay hydrated

Being dehydrated can put a strain on your body and can make you feel hungry, causing you to eat more. Dehydration can also increase the concentration of sugar in your blood. Make sure you drink plenty of water throughout the day.

Diabetes food FAQs

What foods are good for diabetics?

The best foods for diabetics are nutritious while being low in sugar, low in refined carbohydrates,  low in saturated fat, and low in salt. Makes sure your diet is based on plenty of fruit and vegetables, pulses and whole grains, beans, nuts, lean meat, and low-fat dairy.

The American Diabetes Association provides some of the best options:

  • Plant-based proteins such as tofu, seeds, nuts and beans
  • Chicken and other poultry
  • Fish and seafood containing omega-3 fatty acids, such as salmon, mackerel and tuna
  • Eggs and low-fat dairy

If you eat meat, try to always choose meat that is low in fat (eg. chicken breast) and trim the skin off of poultry.

Foods that contain high-quality carbohydrates and fiber such as nuts, legumes, beans, peas, and lentils may slow the absorption of glucose and help with weight loss which is favorable for diabetics.

The same report suggests that eating beans may help with weight loss and could help regulate blood pressure and cholesterol levels.

What fruits should diabetics avoid?

You can eat fresh fruit if you have diabetes, even watermelon, as the fiber it contains slows down how quickly the sugar is digested and released into your blood. Avoid fruit juice as most of the fiber has been removed. You should also avoid canned fruit in syrup or with added sugar.

Sugar can contribute to weight gain and increases the risk of heart disease and stroke.

Only eat small portions of dried fruit – as dried fruit is essentially shrunken fruit you can easily eat too much in one sitting.

Is watermelon bad for diabetics?

Fruit does contain sugar, but the fiber in fruit slows down how quickly the sugar is digested and released into your blood. The carbohydrates and sugars in watermelon are broken down more quickly than in other fruit. You will find many warnings online that watermelon can cause spikes in blood glucose.

The truth is that small amounts of watermelon will likely not cause unhealthy rises in blood glucose. But it is sensible to eat watermelon in small amounts until you know how your body reacts to it.

Are bananas bad for diabetics?

Bananas are richer in carbohydrates than most other fruit and this has led some people to advise diabetics not to eat them. But you can eat bananas if you have diabetes, as the carbohydrates are still digested relatively slowly. Just do not eat too many bananas at a time to make sure you do not overeat.

What vegetables are bad for diabetics?

Vegetables are a great source of nutrients and slow-release complex carbohydrates for diabetics. You should eat smaller portions of starchy vegetables like potatoes and corn, as they are rich in carbohydrates.

Eat more vegetables like leafy greens, broccoli, sprouts, peppers, asparagus, cauliflower, and eggplant. Avoid any vegetables with added fat, salt, or sugar.

Making the right lifestyle changes

Your diet can help you manage your diabetes and reduce your risk of complications. While it is of course important, it is only one part of living with diabetes. You can make other positive lifestyle changes which help, such as getting regular exercise.

People with diabetes can work with a registered dietitian or healthcare professional to develop a nutrition meal plan with optimal food choices that are right for them.

Uncontrolled diabetes could lead to serious consequences such as kidney disease, heart disease, blindness, and other complications.

As well, medications are also central to controlling and living with diabetes.

Read more about insulin and the top diabetes medications:

If your doctor has prescribed a diabetes medication to you, you may be able to receive your prescription for only $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for prescription assistance.